Inaugural Reward Deficiency Syndrome Summit · Canadian Adults with and Without a History of Traumatic Brain Injuries 13:00-13:20 Gabriela Ilie, St. Michael’s Hospital, Canada Presentation

RDS-Summit

November 16-18, 2015San Francisco, USA

Inaugural

Reward Deficiency Syndrome Summit

Reward Deficiency Syndrome (RDS) in the 21st Century: Epigenetics, Neurogenetic, Neuroimaging Tools for Therapy and Recovery

Sponsors

Program at Glance

November 16, 2015 @ SIERRA B

08:30-09:00 Registrations

09:00-09:30 Introduction to the Reward Deficiency Syndrome Summit

09:30-12:20 Keynote Session I

12:20-17:00 Scientific Session I

17:00-18:00 Special Evening Movie I


09:00-10:40 Keynote Session II

11:00-15:40 Scientific Session II

16:00-17:00 Special Evening Movie II


09:30-11:30 Scientific Session III

Kenneth BlumUniversity of Florida, USA

Presentation on: “Dopamine Resistance” in Brain Reward Circuitry as a Function of Genetic Addiction Risk Score (Garspdx) Polymorphisms in RDS: Synaptamine Complex Variant (Kb220z) Induced “Dopamine Sensitivity” as a Pro-recovery Agent

Kenneth Blum is widely designated as Father of Psychiatric Genetics because of the DRD2 gene and its correlation with various psychiatric disorders including the “Reward Deficiency Syndrome (RDS)” which term he has coined. He is also known as the “Father of Neuro-Nutrient Therapy” for his discovery of successful nutrient therapy for RDS. He holds numerous domestic and foreign patents and is co-founder and Chairman & Chief Scientific Officer (CSO) of LifeGen Inc. He is a former Full Professor in the Department of Pharmacology, University of Texas Health Science Center, San Antonio, Texas; Volunteer Professor in the Department of Psychiatry & McKnight Brain Institute, University of Florida College of Medicine, Gainesville, Florida and Adjunct Full Professor of Psychiatry at the University of Vermont College of Medicine, Burlington, Vermont. He currently serves as Neuroscience advisor for Dominion Diagnostics LLC, North Kingstown, Rhode Island, Malibu Beach Recovery Center, Malibu Beach California, and is the Scientific Director of PATH Foundation, New York. He is an honorary Faculty of IIOAB, India. He has been recently appointed CSO of G&G Holistic Addiction Treatment Centers in North Miami Beach Florida. To his credit he has over 400 publications in peer reviewed journals, 14 books and has received many awards including a Lifetime Achievement Award from the National Institute of Holistic Addiction Studies.

Keynote Session I @ SIERRA BMonday, November 16, 2015DAY 1

David E. Smith is recognized as a national leader in the treatment of addictive disease, the psychopharmacology of drugs, new research strategies in the management of drug abuse problems, and appropriate prescribing practices for physicians. He teaches that addiction is a primary medical illness which is best treated in a multidisciplinary fashion, utilizing the group process and the 12-Step programs of Alcoholics Anonymous, Narcotics Anonymous and Cocaine Anonymous. He lectures on the management of psychoactive drug dependence, including cocaine, alcohol and prescription drugs. He also speaks on the subjects of impaired and recovering clinicians, substance abuse in the workplace, dual diagnosis disorders, and substance abuse and the criminal justice system, among many other topics. He provides medical review of DOT and private industry drug testing and prescription drug plans, and legal consultation. Dr. Smith founded the Haight Ashbury Free Clinics in 1967, inaugurating the principle of “Health Care is a Right, not a Privilege”. He has served on federal, state and local bodies addressing substance use, abuse and treatment, and has received numerous awards, including the 2013 Peter E. Haas Award from the University of California Berkeley. He lectures extensively and is the author/co-author of over 360 professional articles and books, including Unchain Your Brain: 10 Steps to Breaking the Addictions that Steal Your Life, with Dr. Daniel Amen.

David E. SmithUniversity of California at San Francisco, USA

Presentation on: Process Addictions and Addiction Transfer

Keynote Session I : 09:30-12:20

09:30-09:55 09:55-10:20

RDS Summit | Nov 16-18, 2015 | San Francisco, USA 3

Monday, November 16, 2015DAY 1

Presentation on: Reward Deficiency Syndrome in Sports Psychiatry

David Baron is currently Professor and Vice Chair, and Chief of Psychiatry at University Hospital at the Keck School of Medicine, University of Southern California. Dr. Baron is also the Director of the Global Center for Exercise, Psychiatry and Sport at USC and Chairman of the Section on Exercise, Psychiatry and Sport for the World Psychiatric Association/World Health Organization. He is also a current member of the Executive Board of Directors for the International Society of Sports Psychiatrists and the 2010 Consumer Council of America “Top Doc” for Sport Psychiatry. Dr. Baron is the former Deputy Clinical Director of the National Institute of Mental Health and Chair of the Department Psychiatry at the NIH graduate school 1989-1997 and Temple University (1998-2010). He developed, and holds the copyright on the only validated depression screener specifical for athletes (BDSA), which is currently in use in over 7 countries. He has over 30 years of clinical experience in sports medicine and sports psychiatry and has worked with athletes of all ages and levels of competition including NCAA, Olympic, and professional. He has published over 130 peer reviewed publications and presented over 300 scientific presentations in the US and over 30 invited international talks, many in the area of Doping in Sports and Depression, Drug Use and Concussion in athletes. His current clinical and research interests are in the neuropsychiatric sequel of recurrent sub-clinical concussion and TBI in athletes, specifically focused on developing more sensitive, user-friendly screening instruments and methods, and increasing public awareness of this growing problem.

Panayotis K. ThanosUniversity of Buffalo, USA

Presentation on: Dopamine D2, Obesity and Reward Deficiency Syndrome

Panayotis K. Thanos is interested in translational research utilizing various rodent models of psychopathology to better understand the mechanisms involved in substance use disorders (SUD) and addiction including the role of dopamine signaling, genes, environment, as well brain circuit mapping and connectivity changes in food, drug and alcohol abuse. Dr. Thanos is the Director of the Behavioral Neuropharmacology and Neuroimaging Lab and has authored more than 85 peer reviewed articles on reward and addiction.

10:20-10:45 11:05-11:30

Coffee Break: 10:45-11:05

David BaronKeck School of Medicine at USC, USA


Keynote Session I @ SIERRA B


In his 35-year career at VA/UCSF, Dr. Banys has developed two addiction fellowships, has engaged in direct clinical care, research, and teaching of UCSF psychiatry residents and substance abuse physician fellows. Most recently he spent 2½ years living and working in Hanoi to assist in scaling up methadone programs and to develop community screenings for depression. He is a section co-editor (Special Problems) for the 2014 edition of the ASAM Textbook of Addiction Medicine. He is a member of Lt. Governor Gavin Newsom’s Blue Ribbon Commission (BRC) on marijuana law reform, and has written a series of marijuana reform-related briefings available on the BRC and CSAM websites.

John J. Giordano is the former president and founder of the prestigious G & G Holistic Addiction Treatment Center, a 62 bed in-patient/out-patient JACHO accredited addiction treatment facility. He is a therapist, a Certified Addiction Professional (CAP), a Master Addictions Counselor (MAC), and a Certified Criminal Justice Specialist (CCJS). He also earned a Masters Certification in Neuro linguistics Programming (NLP), and is a Certified Eye Movement Desensitization and Reprocessing (EMDR) Specialist and a professional expert witness for the state and federal government. He is also a Karate Grand Master 10th degree black belt. He is also certified in Traditional Indian Medicine as well as Mindfulness and Powerful Mind-Body Awareness Therapy Skills. Most recently, he was awarded an Honorary Doctorate of Humane Letters from Mount Sinai University. His Influential book, Proven Holistic Treatment for Addiction & Chronic Relapse, is being utilized by several state hospitals and numerous treatment centers across the country.

Peter BanysUniversity of California at San Francisco, USA

John J. GiordanoNational Institute For Holistic

Addiction Studies, USA

Presentation on: The Evolving Landscape of International Drug Policy Reforms and Cannabis Legalization in California

Presentation on: Comprehensive Holistic Approaches in Addiction Medicine

11:30-11:55 11:55-12:20


Keynote Session I @ SIERRA B

Substance Abuse


Lunch Break: 13:20-14:20 @ Tiburon-Sausalito

Presentation on: Polysubstance Use and Brain Function. Why Bother? Dieter J. Meyerhoff, University of California at San Francisco, USA

12:2

0-12

:40

Presentation on: Interactions Between Methamphetamine and Stress: A Dangerous Combination Bryan K. Yamamoto, Indiana University School of Medicine, USA

12:4

0-13

:00

Presentation on: Mental Health and Substance Use Correlates in a Population Sample of Canadian Adults with and Without a History of Traumatic Brain Injuries Gabriela Ilie, St. Michael’s Hospital, Canada

13:0

0-13

:20

Presentation on: Role of A5 Subunit Containing Nicotinic Receptors in Key Circuits Involved In Nicotinic Addiction and Beyond Rouba Kozak, Pfizer Inc., USA

14:2

0-14

:40

Presentation on: Quality of Life of Users of Psychoactive Substances, Relatives and Non-Users Tais de Campos Moreira, Federal University of Health Sciences of Porto Alegre /UFCSPA, Brazil

14:4

0-15

:00

Presentation on: The Concerning State of Opioid Addiction Trials and Guidelines: To Whom Does this Evidence Apply Zainab Samaan, McMaster University, Canada

15:0

0-15

:20

Presentation on: Medication Abuse in Europe: Which Pharmacoepidemiological Ressources? Maryse Lapeyre Mestre, University of Toulouse, France

15:2

0-15

:40

Presentation on: “This is your Brain on Drugs”: Adolescent Substance Use Prevention Through Neuroscience EducationSion K. Harris, Boston Children’s Hospital, USA

15:4

0-16

:00


Reception: 18:00-19:00

Michael R. DeLeon, Steered Straight, Inc., USAAn American EpidemicSpecial Evening Movie

17:00-18:00

David E. Smith, University of California at San Francisco, USADieter J. Meyerhoff, University of California at San Francisco, USASession Chairs:


Scientific Session I @ SIERRA B: 12:20-17:00

Presentation on: Family Members Affected by a Relative’s Substance Misuse Looking for Social Support: Who Are They? Maria de Fatima Padin, Federal University of Sao Paul, Brazil

16:2

0-16

:40

Presentation on: ADAR2-Dependent GluA2 Editing Regulates Cocaine Seeking Ghazaleh Sadri Vakili, Mass General Institute for Neurodegenerative Disease, USA

16:4

0-17

:00

Tuesday, November 17, 2015DAY 2

Rajendra D. BadgaiyanUniversity of Minnesota, USA

Presentation on: Dopamine Neurotransmission In Reward Deficiency Syndrome

Rajendra D. Badgaiyan is the Director and Principal Investigator of Molecular and Functional Brain Imaging Laboratory and Director of the University Laboratory for Advanced Radiochemistry. He graduated from Gandhi Medical College, Bhopal in India and completed his psychiatry residency training at Harvard Medical School. He had postdoctoral training in cognitive neuroscience at University of Oregon, University of Pittsburgh and Harvard University. He also had training in molecular imaging at Massachusetts General Hospital, Boston, and clinical research training at MIT. He is board certified in General Psychiatry and in Addiction Medicine. He is a member of a numerous National and International Scientific Societies. He is the Editor-in-Chief of 7 international scientific journals and a member of the editorial board of over 40 other scientific publications. He has organized a number of International conferences and symposia.

Timothy D. Brewerton, MD, DFAPA, FAED, DFAACAP is Clinical Professor of Psychiatry & Behavioral Sciences at the MUSC (Charleston), and Executive Medical Director of the Hearth Center for Eating Disorders (Columbia, SC). He is triple board certified in general, child/adolescent and forensic psychiatry; Distinguished Fellow of the APA and the AACAP; Founding Fellow of the Academy of Eating Disorders; former president of the Eating Disorders Research Society; author of over 140 articles/book chapters; Editor of the Clinical Handbook of Eating Disorders: An Integrated Approach (2004), Co-editor of Eating Disorders, Addictions, and Substance Use Disorders: Research, Clinical and Treatment Perspectives (2014).

Timothy D. BrewertonThe Hearth Center for Eating Disorders, USA

Presentation on: Are Eating Disorders Reward Deficiency Syndromes?

09:00-09:25 09:25-09:50

Keynote Session II : 09:00-11:00


Keynote Session II @ SIERRA B


Marcelo FeboUniversity of Florida, USA

Presentation on: Resting State Functional Connectivity in Rat Brain During Extended Daily Access to Cocaine and Abstinence

Marcelo Febo completed his PhD at the University of Puerto Rico Medical School and postdoctoral studies at the University of Massachusetts Medical Center. His work focuses on measuring in vivo functional and structural changes in the rat brain following chronic drug exposure. Over the past decade he has pursued this goal through the use of high field functional magnetic resonance imaging in awake rats and mice. He has been funded early in his career by the National Institute on Drug Abuse to examine the relationship between cocaine sensitization and alterations in maternal brain activity. He is presently Program Director of Translational Research Imaging at the University of Florida Brain Institute and is also a faculty member of the Department of Psychiatry.

Giulio Maria Pasinetti Mount Sinai School of Medicine, USA

Presentation on: Novel Prophylactic and Therapeutic Interventions for Stress-Induced Depression

Giulio Maria Pasinetti is a Professor of Psychiatry, Professor of Neuroscience and Professor of Geriatrics and Adult Development, in the Department of Psychiatry at Mount Sinai School of Medicine, New York. He graduated from Milan University School of Medicine in 1982, and he received his PhD from the University of Milan in 1988. He joined the Mount Sinai School of Medicine’s faculty in 1996 and has consistently maintained an outstanding record of excellence and exceptional productivity.He was also recently awarded with an NIH funded research grant supporting a ‘’Center of Excellence for Research in Complementary and Alternative Medicine in Alzheimer’s disease,’’ of which he is the Principal Investigator and Director. The NIH funded Center is the first in the country exploring the potential beneficial role of natural grape -derived polyphenolic compounds implicated in mechanisms associated with the prevention of Alzheimer’s disease (AD) neuropathology. He also serves as the Director of the Basic and Biomedical Research and Training Program, GRECC James J. Peters Veterans Affairs Medical Center at the Bronx VA.

09:50-10:15 10:15-10:40



Keynote Session II @ SIERRA B


Addiction Treatment

Alcoholism

Presentation on: Greater Mesolimbic Loss-Sensitivity in Young Adult Social Drinkers at Risk for Alcohol Dependence Jane E. Joseph, Medical University of South Carolina, USA

15:0

0-15

:20

Presentation on: Dopaminergic Pathways in Alcohol Dependence: First Data on Indian Population Meera Vaswani, All India Institute of Medical Sciences, India

15:2

0-15

:40


Presentation on: Similarities and Differences in Neurocognitive and Neuroimaging Findings among Internet Gaming Disorder and Alcohol Use Disorder Jung Seok Choi, Seoul National University College of Medicine, South Korea

14:4

0-15

:00

Presentation on: Promoting Epigenetic Networks using Biopsycho-Spiritual Approaches for Treating Prescription Opioid AddictionDeborah Matteliano, State University of New York, USA

11:2

0-11

:40

Presentation on: An Assessment of Outcomes Measure Implementation in the Addiction Treatment Space Alexander K. Moler, Alexandra L. Carlin, The Coalition Against Drug Abuse, USA

Presentation on: Modeling RecoveryBrett C. Ginsburg, The University of Texas Health Science Center at San Antonio, USA

11:4

0-12

:00

Presentation on: Getting In and Out Whole: Connecting with Patients Emotional Pain in the Psychiatric SettingJudith Van Sant, Our Lady of Lourdes School of Nursing, USA

12:0

0-12

:20

12:2

0-12

:40

Presentation on: Integrating Substance Use and Eating Disorder Treatment: Adapting Evidence Based TreatmentsTherese K. Killeen, University of South Carolina, USA

12:4

0-13

:00

Presentation on: Opioid Medications: Efficacy and Risks Norman S. Miller, Bear River Health at Walloon Lake, USA

11:0

0-11

:20

Presentation on: Motivational Interviewing - Patient - Centered Communication in Brief Health Care EncountersTatjana Petrova, Chicago State University, USA

14:0

0-14

:20

Presentation on: Mechanisms of Pain and Opioid PharmacologyThersilla Oberbarnscheidt, Central Michigan University, USA

14:2

0-14

:40

Norman S. Miller, Bear River Health at Walloon Lake, USADeborah Matteliano, University at Buffalo, USASession Chairs:


Scientific Session II @ SIERRA B: 11:00-15:40

DAY 3 Wednesday November 18, 2015

Presentation on: Expression of Reward Reficiency Syndrome Depends on More than Dopamine David Nussbaum, University of Toronto, Canada

09:3

0-09

:50

Presentation on: Fetal Alcohol Spectrum Disorder-Can Prenatal Nutrition Strategy Make a Difference for Brain Development? Miyoung Suh, University of Manitoba, Canada

09:5

0-10

:10

Presentation on: Reward Deficiency Syndrome: Attentional/Arousal Subtypes, Limitations of Current Diagnostic Nosology, and Future Research Edward J. Modestino, Massachusetts College of Pharmacy and Health Sciences, USA

10:1

0-10

:30

Presentation on: The Oxidative Stress Induced Nitric Oxide Dependent Mitochondrial DNA Overproliferation and Deletion in the Context of the Cancer and Neurodegeneration: Recent Challenge Gjumrakch Aliev, GALLY International Biomedical Research Consulting LLC., USA10

:30-

10:5

0


Gregory A. Smith,MD, Pain MD Productions, USAhttp://drgregorysmith.com/

American Addict 2Special Evening Movie16:00-17:00

Presentation on: Role of Mesolimbic Dopamine in Food and Drug RewardValentina Bassareo, University of Cagliari, Italy

11:1

0-11

:30

10:5

0-11

:10

Presentation on: A Glutamatergic Reward Input from the Dorsal Raphe to the Ventral Tegmental Dopamine NeuronsMarisela Morales, National Institute on Drug Abuse, USA

Edward J. Modestino, Massachusetts College of Pharmacy and Health Sciences, USADavid Nussbaum, University of Toronto, CanadaSession Chairs:

Departures


Scientific Session III @ SIERRA B: 09:30-11:30

Neurobiology of RDS


Notes

We wish to meet you again at

RDS Summit- 2016

# 2088 B2 Walsh Avenue, Santa Clara, CA 95050, USAPh: +1-408-426-4832, +1-408-426-4833; Toll Free: +1-844-395-4102

Fax: +1-408-426-4869Email: [email protected]

[email protected] Web: www.unitedscientificgroup.com

www.blumsrewarddeficiencysyndrome.com/summit

UNITED Scientific Group

Documents

Inaugural Reward Deficiency Syndrome Summit · Canadian Adults with and Without a History of Traumatic Brain Injuries 13:00-13:20 Gabriela Ilie, St. Michael’s Hospital, Canada Presentation