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1
Remington Pharmaceutical Industry
Origins and Evolution of Pharmaceutical Industry
The modern pharmaceutical industry is a highly competitive non-assembled1 global
industry. Its origins can be traced back to the nascent chemical industry of the late
nineteenth century in the Upper Rhine Valley near Basel, Switzerland when
dyestuffs were found to have antiseptic properties. A host of modern pharmaceutical
companies all started out as Rhine-based family dyestuff and chemical companies
e.g. Hoffman-La Roche, Sandoz, Ciba-Geigy (the product of a merger between Ciba
and Geiger), and Novartis2 etc. Most are still going strong today.
Over time many of these chemical companies moved into the production of
pharmaceuticals and other synthetic chemicals and they gradually evolved into
global players. The introduction and success of penicillin in the early forties and the
relative success of other innovative drugs, institutionalized research and
development (R&D) efforts in the industry 4. The industry expanded rapidly in the
sixties, benefiting from new discoveries and a lax regulatory environment. During
this period healthcare spending boomed as global economies prospered.
The industry witnessed major developments in the seventies with the introduction of
tighter regulatory controls, especially with the introduction of regulations governing
the manufacture of ‘generics’5. The new regulations revoked permanent patents and
established fixed periods on patent protection for branded products, a result of which
the market for ‘branded generics’6 emerged.
2
Brief Introduction
For over 100 years, Remington has been the definitive textbook and reference on the
science and practice of pharmacy. This Twenty-First Edition keeps pace with recent
changes in the pharmacy curriculum and professional pharmacy practice.
More than 95 new contributors and 5 new section editors provide fresh perspectives
on the field. New chapters include pharmacogenomics, application of ethical
principles to practice dilemmas, technology and automation, professional
communication, medication errors, re-engineering pharmacy practice, management
of special risk medicines, specialization in pharmacy practice, disease state
management, emergency patient care, and wound care.
Purchasers of this textbook are entitled to a new, fully indexed Bonus CD-ROM,
affording instant access to the full content of Remington in a convenient and
portable format.
A must-have resource for all in the pharmaceutical industry!
With over two decades of serving your healthcare needs and a vision to enhance the
quality of life, Remington Pharmaceuticals is committed to providing you with best
healthcare solutions. We develop and manufacture pharmaceutical medicines
through our dedicated R&D team and state-of-the-art manufacturing facilities to
ensure not only a healthier today but also, a healthier tomorrow!
Keeping in mind the need for provision of better healthcare services, Remington
aims at providing high-class medicines with greater access for the benefit of
everyone. The company dedicatedly works towards improving the quality of human
life through continuous innovation and hard-work to bring forth a stream of
medicinal products that contribute to the betterment of the society. Remington offers
a broad portfolio of medicines seeking to give maximum benefit to patients.
3
Among the medical professionals and other stakeholders, Remington is best known
for its dedicated people, passion for innovation through research and development
and quality healthcare solutions. Determined to always go beyond its reputation, the
recent development of its new state-of-the-art manufacturing facility is a testimony
of our continuous efforts to bring Remington to the global fore.
Company Information
With over two decades of serving your healthcare needs and a vision to enhance the
quality of life, Remington Pharmaceuticals is committed to providing you with best
healthcare solutions. We develop and manufacture pharmaceutical medicines
through our dedicated R&D team and state-of-the-art manufacturing facilities to
ensure not only a healthier today but also, a healthier tomorrow!
Keeping in mind the need for provision of better healthcare services, Remington
aims at providing high-class medicines with greater access for the benefit of
everyone. The company dedicatedly works towards improving the quality of human
life through continuous innovation and hard-work to bring forth a stream of
medicinal products that contribute to the betterment of the society. Remington offers
a broad portfolio of medicines seeking to give maximum benefit to patients.
Among the medical professionals and other stakeholders, Remington is best known
for its dedicated people, passion for innovation through research and development
and quality healthcare solutions. Determined to always go beyond its reputation, the
recent development of its new state-of-the-art manufacturing facility is a testimony
of our continuous efforts to bring Remington to the global fore.
With a diligent team and a cGMP compliant, 150,000 sq. ft. manufacturing facility
equipped with latest technology, Remington is devoted on ensuring that it delivers
and fulfils its commitments to the fullest. Strictly adhering to international
4
maintenance and monitoring standards and stringent quality control checks, the
company has established an edge over its competitors enabling it to become the
industry benchmark. According to the IMS, Switzerland (Q1, 2008), Remington is
ranked among the top 30 companies from 681 pharmaceutical companies in Pakistan
in terms of unit-wise sales.
Here at Remington, we uphold strong moral values and instill them in our team. We
inculcate an environment that is based on ethical workings and integrity. The
company has also been working towards providing healthcare services to those who
are impoverished and in places where they are non-existent. We believe in giving
back to the society and for that purpose, the company helped establish Pakistan’s
first private pharmaceutical college and has also been funding a number of NGOs
and other non-profit organization such as Red Cross and Ameer Begum Welfare
Trust (ABWT).
In a world that is rapidly growing, Remington’s dynamic thinking and forward-
looking attitude has made it more adaptable to the changing needs of people. The
company envisions growth and partnerships that stretch across the globe. An
infrastructure of global standards, a concatenate R&D team, technological
advancements, long-lasting customer relationships and a mindset geared towards
growth are the key ingredients that are bound to make the company a success in the
future as well.
Company Values
• Creativity leads to innovation which lays the foundation for success.
• Innovative and updated technology to produce the best quality products.
• Utmost care for employees, customers and the society we live in.
• Respect the employees and their contributions at workplace.
5
• Committed to the highest standards of ethics and integrity.
• Teamwork is the lifeblood of the organization.
• Trust in the relationships with clients.
Message from the C.E.O
I would like to thank everyone who has been directly or indirectly involved in
supporting our efforts to make Remington’s name synonymous to trust and quality.
It is with the untiring efforts of our Research & Development, Production, Quality
Assurance, Material Management, Engineering, Sales & Marketing, Regulatory
Affairs, Human Resource and Corporate Finance teams, that we have achieved
many valuable milestones in the short history of the Company.
Not only Remington, but the whole Pharmaceutical industry in Pakistan is at the
crossroads to be counted or to be neglected in the global arena. At Remington we
have committed all our energies towards making ourselves a recognized leader in
the global pharmaceutical industry by providing quality medicines at an affordable
price.
The new millennium represents the promise of a better future and the reality of rapid
and unpredictable change. To excel, those who will manage, must combine logic
with intuition and solid academic training with bold vision.
Dr. Khokhar is one of the leading figures in the pharmaceutical sector of the
country. He has represented the industry on various national and international
forums. He has been elected Chairman of Pakistan Pharmaceutical Manufacturer's
Association (PPMA) twice and has been the President of Pakistan Pharmacist
Association (PPA), Punjab. He represented PPMA on the Registration and Licensing
Boards, Ministry of Health - Pakistan.
6
He has been a member of various national policy making bodies, including the
Committee for Monitoring Drugs Sector (CMDS), the Board of Governors of
Pakistan Medical Research Council (PMRC), the Central Pharmacy Council, the
Governing Council of Pakistan Council of Scientific and Industrial Research
(PCSIR). He has also been a member of the Pakistan Pharmacopoeia Committee, the
National Formulary Committee, the Good Manufacturing Practice Award
Committee and the Private Sector Advisory Council - constituted by the Prime
Minister of Pakistan. On behalf of the Government of Pakistan and the Company,
Dr. Khokhar has attended numerous conferences in North America, Europe and
Asia.
Over his illustrious career, Dr. Khokhar has also contributed significantly in the
education sector of Pakistan. He has been on the Board of Studies and the Board of
Faculty of Pharmacy at the University of Punjab. He was nominated a member of
the Study Group on Pharmacy Education, by the Higher Education Commission
(HEC), Pakistan. He was also instrumental in helping start the first ever private
sector pharmacy institution in Pakistan.
Dr. Khokhar's contributions are not only limited to the corporate and the education
sectors, but also stretch to the field of sports. He is the Life President of Pakistan
Gymnastic Federation (PGF) and has always strived to raise the profile of the sport
in Pakistan. He has also participated in the activities of the Pakistan Olympic
Association, the body which represents Pakistan on the International Olympic
Association.
Along with his accomplishments in the corporate sector, Dr. Khokhar is recognized
as one of the most eminent pharmacists in Pakistan. After completing his B.
Pharmacy from the University of Punjab, he completed his MPhil in Pharmacy from
the University of Wales. He pursued his doctorate at King's College London, where
7
he joined the Research Group of Professor Arnold H. Beckett - an eminent scientist
of world repute. His outstanding contributions during and after his Ph.D. were
greatly appreciated by his co-researchers, he also authored several research papers in
international journals.
Vision and Mission
Remington Pharmaceuticals was established with a vision to enhance the quality of
health care services in Pakistan. Today, we have not only become the benchmark in
producing superior quality medicines while adhering to the international standards,
but we have also contributed significantly in upgrading the healthcare services in
many parts of rural and urban Pakistan.
Ophthalmology is an expertise area that Remington pharmaceutical now
successfully dominates. Our product brand portfolio covers a wide range of
therapeutic areas, the major ones being Ophthalmic medicines, Anti-infective,
Dermatology and Anti? Ulcerant products
According to the data released by IMS (Switzerland) for the first quarter of 2005,
Remington Pharmaceuticals is ranked 17th (Unit wise) among the 596
pharmaceutical companies in Pakistan.
Credit to Success
We conduct ourselves with the utmost Integrity in all our dealings
Good is the enemy of Great. We must strive for Excellence
Innovative thinking leads to out-of-the-box solutions. Always add value!
Perseverance should be a habit. Never ever give up!
People are our guiding beacon. Promptly deliver to their needs
8
Trust Regmination
We strive for excellence in every mile we run. Nothing takes our attention more than
delivering quality products to doctors, pharmacists and patients. That is why today,
Remington is taking care of millions of people trusting our medicines for their
wellbeing.
Our manufacturing facilities are designed to ensure our commitment to quality at
every step of the production process. Computerized building management systems
provide required environment round the clock and, in addition to that, extensive
equipment automation ensuring Quality by Design.
We work hard as a team so that you can be rest assured of getting the highest quality
medicine from Remington.
Structu ral Industry Analysis (Porter’s Five Forces)
This section provides a summary positional analysis of the pharmaceutical industry
using Porter’s Five Forces model (see diagram below)
9
• Barrier to entry: High (Pharmaceuticals). Cost of R&D and patent limitations
• Industry Competition: High. Advantages gained by first mover advantage
(patents)
• Suppliers: supplier power is low
• Buyers: buyer power is low
• Substitutes: low (with patents) medium (after patent expiry)
Overall, the pharmaceutical industry shows an upward trend in its core markets. The
industry remains highly valued has a favorable market position with strong financial
make-up and strong earnings growth. Its future potential demand trend is positive
and despite increased competition the industry still shows a continuing upward
growth momentum. Datamonitor’s9 forecast of the leading 16 pharmaceutical
companies for 2001 to 2007 suggests that combined sales will grow at a minimum
rate of 5.2 percent based on the potential of their product pipeline.
Products
Remington manufactures and markets pharmaceutical drugs. A manufacturing
facility equipped with state-of-the-art technology and an extremely competent R&D
team ensures that the products provided by the company meet international
standards and are of the highest quality. The company’s product base covers a wide
range of therapeutic areas. We make sure that our medicinal products exactly fulfill
the requirements of both physicians and patients. Through continuous innovation,
we aim to keep broadening our product mix to serve an increasingly large number of
therapeutic areas. We focus on upholding and furthering our brand name and in
becoming a market-wide leader in the pharmaceutical industry.
10
Products for International Market
Remington manufactures and markets pharmaceutical drugs. A manufacturing
facility equipped with state-of-the-art technology and an extremely competent R&D
team ensures that the products provided by the company meet international
standards and are of the highest quality. The company’s product base covers a wide
range of therapeutic areas. We make sure that our medicinal products exactly fulfill
the requirements of both physicians and patients. Through continuous innovation,
we aim to keep broadening our product mix to serve an increasingly large number of
therapeutic areas. We focus on upholding and furthering our brand name and in
becoming a market-wide leader in the pharmaceutical industry.
ANTHELMINITIC
GENERIC NAME BRAND NAME PRODUCT TYPEPACK
SIZEPACK TYPE
Piperazine REMIPAR
ELIXIR
Syrup 30ml Glass Bottle
ANTI-ANAEMIC
GENERIC NAMEBRAND
NAME
PRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Iron (III) Hydroxide
Polymaltose Complex
FEMTOL Syrup 60ml Glass
Bottle
11
Iron (III) Hydroxide Polymaltose
Complex
FEMTOL Tablets 10’s Blister
Iron (III) Hydroxide Polymaltose
Complex
FEMTOL-F Tablets 10’s Blister
ANTI-ASTHMATIC
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Ketotifen ASFEN Syrup 60ml Glass
Bottle
Ketotifen ASFEN Tablets 30’s Blister
Montelukast REMIKAIR 4mg Sachet 28’s Aluminiu
m
Montelukast REMIKAIR 4mg /
5mg / 10mg
Tablets 14’s Blister
ANTI-BACTERIAL QUINOLONE
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Ciprofloxacin ROCIP 250mg /
500mg
Tablets 10’s Blister
Levofloxacin KOBEXIN 250mg /
500mg
Tablets 10’s Blister
Moxifloxacin OCUMOX Tablets 5’s Blister
Norfloxacin BACTINOR Tablets 14’s Blister
12
Ofloxacin CIOF Tablets 10’s Blister
Sparfloxacin Q-LOX 100mg /
200mg
Tablets 10’s Blister
ANTI-BIOTIC / ANTI-INFECTIVE
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Amoxycillin WISEP Drops 10ml Glass
Bottle
Amoxycillin WISEP Suspension 60ml Glass
Bottle
Amoxycillin WISEP Tablets 100’s Blister
Amoxycillin WISEP-1000 Tablets 10’s Blister
Amoxycillin WISEP-DS Suspension 60ml Glass
Bottle
Amoxycillin WISEP-DS Tablets 20’s Blister
Amoxicillin-Clavulanic
Acid
MAGNICILLIN Tablets 6’s Blister
Amoxicillin-Clavulanic
Acid
MAGNICILLIN Suspension 60ml Glass
Bottle
Amoxycillin-
Flucloxacillin
FLOMOXIN Capsules 20’s Plastic
Bottle
Amoxycillin- FLOMOXIN Suspension 45ml Glass
13
Flucloxacillin Bottle
Azithromycin MACRO-AZ Capsules 10’s Plastic
Bottle
Azithromycin MACRO-AZ Suspension 15ml Glass
Bottle
Cefadroxil DROXIL Capsules 12’s Plastic
Bottle
Cefadroxil DROXIL Suspension 60ml Glass
Bottle
Cefadroxil DROXIL-1000 Tablets 10’s Blister
Cefadroxil DROXIL-DS Suspension 60ml Glass
Bottle
Cefixime ZYLOFIXIM Capsules 5’s Plastic
Bottle
Cefixime ZYLOFIXIM Suspension 30ml Glass
Bottle
Cefixime ZYLOFIXIM-DS Suspension 30ml Glass
Bottle
Cephradine ZEFLIN Capsules 12’s Plastic
Bottle
Cephradine ZEFLIN Suspension 60ml Glass
Bottle
Cephradine ZEFLIN-DS Capsules 12’s Plastic
14
Bottle
Cephradine ZEFLIN-DS Suspension 60ml Glass
Bottle
Doxycycline Hyclate VOXIN Tablets 20’s Blister
Fosfomycin MIFOS Capsules 10’s Blister
Fosfomycin MIFOS Suspension 60ml Blister
ANTI-CONVULSANT
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Gabapentine NEUROGAB 200mg /
400mg / 600mg
Tablets 10’s Blister
ANTI-DIABETIC
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Glimepiride DIARID 1mg / 2mg /3mg /
4mg
Tablets 20’s Blister
Glimepiride-Metformin DIARID-M 1mg-500mg Tablets 30’s Blister
Pioglitazone XOGLIT 15mg / 30mg /
45mg
Tablets 14’s Blister
Pioglitazone-Metformin XOGLIT-M 15mg-500mg Tablets 28’s Blister
Pioglitazone-Metformin XOGLIT-M 15mg-850mg Tablets 14’s Blister
ANTI-EMETIC
15
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Domperidone KOMETIC Suspension 120ml Glass Bottle
Domperidone KOMETIC Tablets 50’s Blister
ANTI-HISTAMINE
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Cetrizine ZINOLUR Tablets 10’s Blister
Loratidine TILORA Syrup 60ml Glass Bottle
Loratidine TILORA Tablets 10’s Blister
ANTI-OBESITY
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Sibutramine LOWBEST 10mg /
15mg
Capsules 14’s Blister
ANTI-PEPTIC ULCERANT
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Cimetidine SEMAG Tablets 10’s Blister
Famotidine TINOPEP 20mg Tablets 20’s Blister
Famotidine TINOPEP 40mg Tablets 10’s Blister
Omeprazole INGIS Capsules 14’s Plastic
16
Bottle
Pantoprazole PANTO Tablets 14’s Blister
Ranitidine RANIFUR Tablets 10’s Blister
Ranitidine RANIFUR-DS Tablets 10’s Blister
Lansoprazole ZOXILAN Capsules 14’s Plastic
Bottle
ANTI-RHEUMATIC
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Diclofenac Potassium FLAMY 50mg Tablets 20’s Blister
Diclofenac Potassium FLAMY 100mg Tablets 10’s Blister
Diclofenac Sodium KONAC Tablets 20’s Blister
Flurbiprofen FLURIBEC Tablets 30’s Blister
Leflunomide RHEUMID 10mg /
20mg
Tablets 30’s Blister
Meloxicam MELOX 7.5mg / 15mg Tablets 10’s Blister
Piroxicam KEMROX 10mg / 20mg Capsules 1’s Blister
ANTI-VIRAL
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Ribavrin VIROFF 100mg / 200mg / Capsules 10’s Blister
17
400mg
Ribavrin VIROFF 600mg Tablets 10’s Blister
Ribavrin VIROFF 50mg / 100mg Syrup 60ml Glass
Bottle
CARDIOVASCULAR
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
Simvastatin-Ezetimibe TIMVAST PLUS 10mg-10mg /
20mg-10mg
Tablets 7’s
Simvastatin-Ezetimibe TIMVAST PLUS 40mg-10mg Tablets 10’s
Rosuvastatin ROSULIP 5mg / 10mg / 20mg Tablets 10’s
Candesartan KANPRESS 8mg Tablets 14’s
Candesartan KANPRESS 16mg Tablets 28’s
Candesartan-
Hydrochlorothiazide
KANPRESS PLUS Tablets 28’s
Clopidogrel-Aspirin CEGREL-A 75mg-75mg / 75mg-
150mg
Tablets 10’s
Lisinopril-
Hydrochlorothiazide
ZIDOPRIL Tablets 28’s
Ramipril RAPRIL 1.25mg / 2.5mg / 5mg /
10mg
Tablets 28’s
Amlodipine-Atorvastatin MYODIP 5mg-10mg / 5mg-Tablets 7’s
18
20mg
Amlodipine-Atorvastatin MYODIP 10mg-10mg Tablets 10’s
Valsartan VALZAR 80mg / 160mg Tablets 14’s
Valsartan-
Hydrochlorothiazide
VALZAR PLUS 80mg-12.5mg Tablets 28’s
Valsartan-
Hydrochlorothiazide
VALZAR PLUS 160mg-25mg Tablets 14’s
COUGH & COLD PREPARATIONS
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Ammonium Chloride REMISOLE
EXPECTORANT
Syrup 60ml /
120ml
Glass
Bottle
DERMATOLOGY
GENERIC NAME BRAND NAMEPRODUCT
TYPEPACK SIZE PACK TYPE
Benzyl Banzoate S.P. LOTION Lotion 60ml /
120ml
Glass Bottle
Flucinolone Acetonide CINOL Cream 15gm Aluminium
Tube
Flucinolone Acetonide CINOL Ointment 15gm Aluminium
Tube
19
Flucinolone Acetonide-
Neomycin
CINOL-N Cream 15gm Aluminium
Tube
Flucinolone Acetonide-
Neomycin
CINOL-N Ointment 15gm Aluminium
Tube
Miconazole Nitrate MONITIN Cream 30gm Aluminium
Tube
Miconazole Nitrate GYNO MONITIN Cream 20gm Aluminium
Tube
Miconazole Nitrate-
Diflucortolone
MONICORT Cream 10gm Aluminium
Tube
Polymyxin B. Sulfate-Zinc
Bacitracin
ZYLOSPORE Ointment 10gm/20gm Aluminium
Tube
Salicylic Acid-Sulphur SEPRODERM Ointment 20gm Glass Bottle
EAR, NOSE & THROAT
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
Betamethasone BETADROP Ear Drops 7.5ml
Betamethasone-Neomycin BETADROP-N Ear Drops 7.5ml
Chloramphenicol REMICOL Ear Drops 10ml
Ciprofloxacin-Lignocaine LIGNOCIP Ear Drops 5ml
20
Ciprofloxacin OTOCIP Ear Drops 5ml
Dexamethasone-Ciprofloxacin DEXCIP Ear
Suspension
5ml
Fluticasone Propionate FLUTEX Nasal Spray 15ml
Gentamicin OPTAGEN Ear Drops 7.5ml
Gentamicin-Hydrocotisone OPTAGEN-HC Ear Drops 5ml
Levofloxacin-
Dexamethasone
LEFODEX Ear
Suspension
5ml
Ofloxacin 0.3% KUNOXY Ear Drops 5ml
Ofloxacin 0.6% KUNOXY Plus Ear Drops 5ml
Polymyxin-Neomycin-
Hydrocortisone Acetate
POLYSPORE-HC Ear
Suspension
5ml
Polymyxin B-Lignocaine OTOCAINE Ear Drops 5ml
Sodium Cromoglycate NOSOCROM Nasal Spray 15ml
21
Sodium Cromoglycate-
Xylometazoline
NOSOCROM -X Nasal Spray 13ml
Tobramycin TOBEC Ear Drops 5ml
Tobramycin-Dexamethasone TOBEC-D Ear Drops 5ml
Triamcinolone Acetonide NOSOLONE-AQ Nasal Spray 15ml
EYE DROPS
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
Atropine Sulphate OPTA ATROPINE Solution 10ml
Betamethasone BETADROP Solution 7.5ml
Betamethasone-Neomycin BETADROP-N Solution 7.5ml
Chloramphenicol OPTACHLOR Solution 10ml
Chloramphenicol-Dexamethasone METHACHLOR Solution 5ml
Ciprofloxacin ROCIP Solution 5ml
22
Dexamethasone OPTADEX Solution 5ml
Dexamethasone-Neomycin OPTADEX-N Solution 5ml
Dexamethasone-Neomycin-
Polymyxin B.
STERIBIOL Suspension 5ml
Dexamethasone-Sulphacetamide METHASUL Solution 5ml
Dexamethasone-Polymyxin B.-
Neomycin
POLYDEX Solution 5ml
Diclofenac Sodium KONAC Solution 5ml
Flourometholone-
Tetrahydrozoline
FEMICON Suspension 5ml
Gentamicin OPTAGEN Solution 7.5ml
Gentamicin-Hydrocortisone OPTAGEN-HC Solution 5ml
H.P.M.C. HICEL Solution 5ml
Latanoprost PROSTILET Solution 2.5ml
Latanoprost-Timolol PROSTILET-T Solution 2.5ml
23
Moxifloxacin OCUMOX Solution 5ml
Norfloxacin BACTINOR Solution 5ml
Ofloxacin CIOF Solution 5ml
Prednisolone-Neomycin-
Polymyxin B.
BIOPRED Suspension 5ml
Prednisolone Acetate MILDOPRED Suspension 5ml
Prednisolone Acetate FORTIPRED Suspension 5ml
Prednisolone-Chloramphenicol PREDNICOL Suspension 10ml
Prednisolone-Sulphacetamide MYDOSONE Suspension 5ml
Pyrilamine Maleate-
Phenylephrine
DECON-A Solution 15ml
Sodium Cromoglycate HISTALYN Solution 5ml
Sodium Cromoglycate-
Tetrahydrozoline
HISTAZOLIN Solution 15ml
24
Sulphacetamide Sodium OPTACID 10% / 20%
30%
Solution 10ml
Timolol BLOTIM 0.25% / 0.5% Solution 5ml
Tobramycin NEBRA Solution 5ml
Tropicamide MYDROMIDE Solution 5ml
EYE OINTMENT
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZEPACK TYPE
Acyclovir LOVIR Ointment 4.5gm Aluminium
Tube
Atropine Sulphate MYDRA Ointment 3gm Aluminium
Tube
Betamethasone-Neomycin BETA-N Ointment 3gm Aluminium
Tube
Chloramphenicol OPTACHLOR Ointment 5gm Aluminium
Tube
Chloramphenicol-
Dexamethasone
METHACHLOR Ointment 3gm Aluminium
Tube
Chlorobutanol T-WET Ointment 3.5gm Aluminium
Tube
25
Ciprofloxacin ROCIP Ointment 3.5gm Aluminium
Tube
Dexamethasone-
Sulphacetamide
METHASUL Ointment 3.5gm Aluminium
Tube
Neomycin - Polymyxin B.
-Dexamethasone
STERIBIOL Ointment 3.5gm Aluminium
Tube
Oxytetracycline-
Polymyxin B.
XINOXY Ointment 3gm Aluminium
Tube
Polymyxin-Neomycin-
Zinc Bacitracin
TRIMIN Ointment 5gm Aluminium
Tube
Polymyxin B.-
Zinc Bacitracin
ZYLOSPORE Ointment 4gm Aluminium
Tube
Polymyxin B.-
Zinc Bacitracin -
Neomycin -
Hydrocortisone
POLYSPORE-HC Ointment 3gm Aluminium
Tube
Prednisolone-Neomycin-
Polymyxin B
BIOPRED Ointment 3.5gm Aluminium
Tube
Prednisolone-
Sulphacetamide
MYDOSONE Ointment 3.5gm Aluminium
Tube
Tobramycin NEBRA Ointment 5gm Aluminium
Tube
GASTROPROKINETICS
GENERIC NAME BRAND NAME PRODUCT PACK PACK
26
TYPE SIZE TYPE
Itopride TOPRID Tablets 10’s Blister
MUSCLE RELAXANT
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Orphenadrine
Citrate-Paracetamol
FLEXODIN Tablets 100’s Blister
NON NARCOTIC ANALGESIC
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Mefenamic Acid FEBRIN Tablets 100’s Blister
Mefenamic Acid FEBRIN-DS Tablets 100’s Blister
VITAMINS
GENERIC NAME BRAND NAMEPRODUCT
TYPE
PACK
SIZE
PACK
TYPE
Alfacalcidol DOLBON 0.25mcg / 0.5mcg /
1mcg
Tablets 10’s Tablet
Thiamine-Riboflavine-
Pyridoxine-Nicotinamide
PLEXOVIT Syrup 60ml /
120ml
Glass
Bottle
B-Compound
Lysine Syrup
PLEXOVIT-L Syrup 60ml /
120ml
Glass
Bottle
Antioxidant Vitamins
(Beta Carotene, C, E),
VISAVIT Tablets 30’s Plastic
27
Mineral (Zn, Cu, Se),
Folic Acid and
Vitamin D
Bottle
Antioxidant Vitamins
(Beta Carotene, C, E),
Mineral (Zn, Cu, Se),
Folic Acid and
Vitamin D
VISAVIT PLUS Tablets 30’s Plastic
Bottle
Multi Vitamin VITONE Syrup 60ml /
120ml
Glass
Bottle
Multi Vitamin VITONE FORTE Syrup 120ml Glass
Bottle
Multi Vitamin VITONE FORTE Tablets 20’s Plastic
Bottle
International Business
Licensing & Alliances Various Coutries
We at Remington Pharmaceuticals understand the need for collaborative
development and marketing of drugs to achieve higher growth levels. Be that
through in-licensing or co-marketing, we seek to enhance our presence both
regionally and globally by partnering in areas where we can leverage on our
complementary expertise and exploit synergies.
Remington Pharmaceuticals is one of the leading pharmaceutical companies in
Pakistan and with the commencement of a cGMP compliant, 150,000 sq. ft., multi-
drug manufacturing facility we are augmenting our presence in the Asian, Middle
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Eastern and African markets. Built on strong foundations of commitment to
excellence, today, Remington’s strong brand has become synonymous to highest
standards.
Our key strength areas include:
Our team’s in-depth know-how and expertise right from rapid drug
registrations to generating substantial sales in short spans of time.
Our proven business model and strategic understanding of the markets assist
our partners gain forceful market entry across the region.
Our successful track record of carrying out R&D, manufacturing quality drugs
and the marketing skills of our team puts us in a strong position to
successfully execute launches in multiple therapeutic areas.
Our close working relationship with regulatory authorities, medical
professionals and other related associations & societies allows us to introduce
our partner products on a fast track.
Manufacturing Process
Recognition and Appreciation
Our manufacturing facility boasts enhanced production capacities for Eye and Ear
Drops, Ointments, Liquid (Oral) Medicines, Coated and Uncoated Tablets, Capsules
and External Preparations for various therapeutic categories.
The manufacturing facility is equipped with the latest technology including
automated and dedicated process control systems, computerized HVAC/dust control
mechanism, computerized Building Management System (BMS) and, process–water
and waste–water management systems providing with a ready compliance to cGMP,
ISO 9001:2000(E) and ISO 14001. Delegates from Europe and the US have visited
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and admired the quality standards maintained at Remington’s production facilities.
This has led us to formalize transnational relationships and enhance our strategic
partnerships.
Contract Manufacturing
Remington’s dedicated and competent R&D team, a state-of-the-art manufacturing
plant that meets the highest international standards coupled with the company’s vast
experience and expertise in Pharmaceutical Manufacturing and its strong ethical
values ensuring protection of intellectual property rights enable it to provide with a
complete outsourcing solution.
Using cGMP compliant and regulatory authorities’ approved manufacturing
processes, our production facility boasts enhanced production capacities for Eye and
Ear Drops, Ointments, Liquid (Oral) Medicines, Coated and Uncoated Tablets,
Capsules and External Preparations for various therapeutic categories.
At Remington, an ISO 9001:2000(E) certified company, a planned and systematic
pattern of all means and actions is designed to ensure that its products meet the
established standard specifications, legal requirements and the organization’s quality
objectives.
Contract manufacturing carries significant advantages some of which include:
Low Upfront Cost due to minimal capital requirement and a legal and tax presence not
being necessary
Flexibility through being able to ramp up production volumes rapidly
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Fast-track Processing as a consequence of short lead-team for final production
Access to External Expertise
Greater Adaptability to the ever changing demands of the market allowing for greater
revenue growth
The company provides tailored services to meet the clients’ needs by making
available the requested information including the following reports:
Inventory levels & movements
Batch monitoring & reports
Quality assurance reports
We strive to create a win-win situation by providing cost-effective and profitable
solutions for our partners.
Production Capacity
The annual production capacity of each section running on two 8 hour shifts, which
can be extended up to three shifts daily, is as follows:
Capsules 30 million capsules
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Dry Syrups 12 million bottles
Ear Drops 12 million bottles
Eye Drops 60 million bottles
Eye Ointments 12 million tubes
Lotions 14 million bottles
Skin Ointments 12 million jars & tubes
Syrups 60 million bottles
Tablets 800 million tablets
Quality by Design
The manufacturing team is committed to produce highest quality products which can
meet the needs of both doctors and patients. The team strives to manufacture
products that are cost-effective through best utilization of their resources, reduced
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down-time and by extensively applying planned-preventive maintenance program
with coordination of a highly skilled engineering team.
Our production facilities meet the regulatory requirements of cGMP and regulatory
authorities. All the manufacturing activities are performed according to the approved
procedures as required by cGMP and ISO 9001:2000(E) quality management
system.
In addition to quality assurance department's procedures at every stage of
production, in-process checks are also imposed, the results of which are
continuously monitored and recorded. Materials are procured from approved
suppliers through documented procedures, are quarantined until tested and released
for use by the manufacturing department. These materials are dispensed under
strictly controlled conditions supervised by our Quality Assurance team.
QUALITY ASSURANCE
At Remington the core quality management groups cut across all functional
departments to coordinate and monitor the implementation of the quality policy and
quality management system. The quality assurance team effectively focuses on each
step starting from the raw material souring to packing and storing of the finished
products.
Internal Quality Assurance
External Quality Assurance
Effectiveness and Suitability of Quality System
Being an ISO 9001:2000(E) certified company, we have extended our efforts to the
Total Quality Management Program for the benefit of the organization itself, its
members and of the society as a whole.
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To run the quality system effectively and produce highest standard products, all the
required human, material, technical and financial resources are periodically and
thoroughly reviewed. The prime objective is the effective management of our
operations and substantiation of activities within the organization. These resources
include but are not limited to:
Human Resource Skills
Design and Development Equipment
Inspection, Testing and Examination Equipment
Instrumentation and Computer Software
Here at Remington, a planned and systematic pattern of all means and actions is
designed to ensure that our products meet the established standard specifications,
legal requirements and the organization’s quality objectives.
Collaboration Opportunities
Partnering with European / US Companies
For global and specialist pharmaceutical companies looking to enter the Asian,
Middle Eastern and African markets, Remington offers its unique platform to
partner in these regions.
With a vast knowledge of the region, Remington can streamline the difficulties
faced when launching a product in the aforementioned regions. Our team is well
versed in dealing with geographic areas where lack of information on market trends,
healthcare policies and reforms, and local doctors & patients are some of the main
challenges. Using our vast experience we successfully tackle these challenges hence
de-risking the market entry of our partners’ products and providing a perfect
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platform to achieve high growth. We have a step-by-step market entry process that
involves initiating the process by carrying out comprehensive top-down market
analysis followed by formulating optimal strategies for entering a given market.
We appreciate that each partner is unique in its culture and business model; hence
we strive to provide customised solutions to contribute to our business partners'
success. To share the market entry risks, we also co-invest with our partners.
In summary, we are interested in sales and marketing partnerships and are keen to
explore licensing opportunities to create regional successes. We are not limited by
speciality areas and evaluate diverse opportunities to add to our portfolio of products
to expand our therapeutic and geographic coverage. Licensing innovative and ‘first
time’ products in the region across multiple therapeutic classes is of particular
interest to us.
We deal with our partners with highest level of integrity and strive to build long-
lasting, mutually beneficial relationships that add value for us and for our partners.
Research and Development
Remington Pharmaceuticals has developed one of the most progressed and sensitive
R&D facility in the country. The core strength of our team is our foresightedness
that enables us to come up with the desired product at the apposite time. The in-
depth knowledge of the industry, science and the technology help us develop new
and effective products for the most pernicious diseases.
We have on our R&D team scientists with vast knowledgebase. To keep up with the
pace of today’s fast growing pharmaceutical industry, the R&D team regularly
participates in technical programs and seminars so that they are better able to tackle
new challenges and help develop better products. To facilitate the R&D team,
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Remington’s laboratory is designed and equipped to meet international standards.
The R&D team is working on developing multi-therapeutic products pipeline.
At Remington Pharmaceutical we are committed to thrive and bring forth new
products which will help us in serving the humanity in a more effective way. With a
dedicated R&D team and facilities of international standards, we believe that
together we will be able to meet the challenges and continue our drive towards
progress.
COMPANY’S MARKETING & DISTRIBUTION
Laborate follows push strategy with robust distribution system as follows:
The sale generated by company to distributor is termed as Primary sales. Laborate
doesn’t believe in advertisement. It has aggressive and vibrant field force to promote
their products in the market especially to stockiest, retailers as follows:
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Respnesibility
Valuing the community we live in and the environment has always been an integral
part of Remington’s policy. Remington considers itself a part of the community and
has always strived to make a difference for the betterment of the wider populace
through not only providing quality medicines at affordable prices but also, by giving
something back to the community. We have always made sure that our business
operations are carried out in a manner that protection of the environment remains
one of our top most priorities. Remington is moving towards becoming a carbon-
neutral company by offsetting its carbon emissions through the deployment of
renewable energies for power generation.
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Community Support
Remington donates regularly to the NGOs and other foundations to help those who
are in dire need so that they can become responsible citizens and equally contribute
for the advancement of the country. The company continuously supports non-profit/
charitable organizations like Red Cross and ABWT.
The Indian Ocean Tsunami struck in the year 2004 killing millions of people in
areas including India, Sri Lanka, Indonesia and Thailand. Remington stepped up for
the support of all those affected by what was one of the deadliest natural disasters in
history. The company worked with international organizations like the Red Cross to
provide both financial aid and medical provisions to the aforementioned tsunami-
struck areas.
The year 2005, in a time of crisis when the whole country especially the Northern
areas were jolted by strong quakes, being a responsible part of the community,
Remington was among the first few to extend their full financial and emotional
support to the quake-affected people. The company made unrelenting efforts at
making medical provisions available to those affected and helped in the
reconstruction of quake-torn houses.
We believe that education plays a vital role in better equipping the youth to make
positive contributions to the society as a whole and bringing about development.
One of Remington’s keys strengths have been its vast knowledge base and we are
committed on empowering our younger generation with that knowledge and more
and for that purpose, in the 90s the company helped establish Pakistan’s very first
private pharmaceutical college in Lahore. The college aims at providing quality
education and in departing invaluable knowledge to the budding youth of the
country. Our senior management team also regularly gives seminars and conducts
workshops at local public institutions.
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We also promote healthy living and encourage people of all ages to engage in sports.
Recently Remington held a Polo Tournament for this very purpose. Special training
camps were held for younger people so that they make healthy activities a part of
their routines from an early age. The team at Remington also actively participated in
the tournament which served as an effective means for team-building. Remington
has also sponsored a polo team on a number of occasions.
Environment
The world is witnessing increasing globalization with the global markets evolving
continuously. Remington not only strives to adapt itself to the changing needs of the
world but also, in upholding strong values that inculcate in the team an
understanding of the need to protect the environment through clean and efficient
means of manufacturing and production. We believe that through a cleaner
environment we can better ensure a healthier tomorrow.
Analysis of Key Industry Participants and Strategy
This section provides a descriptive overview on the top three pharmaceutical firms
worldwide.
Pfizer\Pharmacia:
After its merger with Warner-Lambert in July 2000, Pfizer became the world’s
largest pharmaceutical company. The strong commercial potential of Pfizer’s
product portfolio and its strong products pipeline, has caused Pfizer to invest heavily
in product support, global sales force expansion and increased R&D spend. In April
2003 the merger of Pfizer Inc. and Pharmacia Corporation was announced. The
estimated $60 billion merger consolidates Pfizer’s position as the world's largest
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pharmaceutical company. The merged entity will control 11% of the global
pharmaceutical market, from 8%, with annual revenue estimated to increase from
$32 billion to $46 billion. The new Pfizer will also control 50% more of the market
than its closest rival, the world's second largest drug company, GlaxoSmithKline10.
The European Commission approved the merger but demanded that the firm divest
pharmaceuticals in nine different areas in response anti-competitive charges.
GlaxoSmithKline:
The December 2000 merger of GlaxoWellcome and SmithKline Beecham created
the GlaxoSmithKline, the world's second largest pharmaceutical company with a
global market share of 7%. GSK has global pharmaceutical sales of over $22bn and
also the largest share in several therapeutic areas, including the vaccine and over-
the-counter products (OTC).
However, GSK is still arguably a more global company (in terms of spread) than
Pfizer, given that GSK generates a far higher proportion of its sales outside the
North American market. GSK is ahead of Pfizer in every other region outside North
America. GSK generated a relatively high $6.0bn, or 26.6% of its sales, in the
European market in the year to September 2002 compared to Pfizer's $3.8bn
(16.9%). The region in which Pfizer's market share is closest to GSK's is Africa,
Asia and Australasia; this is due mainly to GSK’s strong position in the large
Japanese market, which has been targeted by Pfizer for future growth.
Merck & Co:
Merck is the third-largest global pharmaceutical company. Excluding organic
growth, for Merck to rival the top two it will have to acquire at least one of the 15
leading pharmaceutical firms in the world - a smaller acquisition would not gain it
sufficient market share to overtake either Pfizer or GSK. While it has not gone for a
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full-blown merger, Merck, like other drug companies, has increased the number of
collaborations with external and biotech firms. It has so far signed close to 50 deals
with research partners in the past 5 years. Merck has also teamed with Schering-
Plough to develop respiratory drugs. Merck's strategy is to focus on breakthrough
drugs, rather than go the consolidation route or imitate competitors with so-called
"me-too" products. Unfortunately its current product pipeline is rather weak and
Merck may come under increased pressure to merge as a means of gaining market
share and growth. Analysts believe Merck’s ideal merger candidate would be
Johnson & Johnson due to the little overlap with Merck’s pharmaceutical portfolio.
SWOT Analysis and Strategy Review
Since inception in 1849, Pfizer has grown from a small family firm with two
employees into a global enterprise with 95,000 employees on six continents. Pfizer
has increasingly focused its efforts on R&D and this remains its core business
strategy. Pfizer’s strengths lie in its strong pipeline of innovative pharmaceutical
compounds and strong marketing capabilities. Pfizer's performance is characterized
not only by size, but also by growth. In 1999, Pfizer achieved 20% revenue growth.
Pfizer has also set records in each of the past three years to 2003 with the most
successful product launches in pharmaceutical history Lipitor, Viagra and Celebrex.
Pfizer’s strength in R&D, marketing, and sales has made them a partner of choice
for many companies in the pharmaceutical industry and they are involved in a wide
variety of research collaborations and a large number of licensing agreements with
universities, institutes and organizations.
An outline SWOT analysis of the world’s largest pharmaceutical firm follows next.
Strengths
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• R&D innovation with a broad therapeutic coverage
• Marketing strength in major geographical and therapeutic areas
• Existing Patent protection for a number of years on key products
Opportunities
• Decreasing development time through favorable R&D collaborations and
internal efforts
• Emergence of integrated global markets and globalization for new products
• Co-marketing agreements with companies wishing to capitalize on Pfizer's
marketing strengths, providing Pfizer with strong products and therefore
revenue growth
Weaknesses
• Discontinuation of products in the latter stages of development
• Co-marketing agreements can limit Pfizer's global presence
• Increased size and operational complexity makes Pfizer a less agile company
Threats
• Increased competition for core products like Viagra as its high cost
encourages use of cheap alternative treatments
• An increase in the number of safety issues surrounding Viagra
• Competition from products similar to Pfizer's in R&D that reach the market
close to or before Pfizer's products
• The new economic potential of emergent China, India and competition in
diverse regional markets.
Constraints
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1. Found a little bit difficulty initially in meeting with the company guide to get
the assignments due to his busy schedule.
2. Company didn’t want to involve trainees in their business directly.
3. Most of the chemist doesn’t provide their Sales information easily.
Strategy adopted :
1. Strictly follow work-timings from 9:00 a. m to 6:00 p.m.
2. Zeal to learn from existing employees.
3. Passion & Dedication towards work to prove myself.
4. Cooperation and assistance to other employees in their work.
5. Effective Communication and presentation skills.
6. Started sending professional-mails to get the assignments and submission of
reports of the tasks thus making them (Company guide, Chemists and
Retailers) aware the significance of this project in our professional life.
Critique and Analytical Review of
Pfizer’s StrategyPfizer has done quite well historically and analysis has revealed that they are
looking to position Themselves strategically for the future. But as we enter a new
era in the pharmaceutical industry With increased patent risks and lower marginal
product returns, pharmaceutical firms like Pfizer Must restructure their huge
organizational mass to reduce structural inefficiencies, cut costs Which is required to
43
enable them compete better in the changing global environment. Due to it Massive
R&D push, Pfizer suffers a relatively high rate of discontinuation in pre-approval
Products and more focus are required to reduce resource wastage. Pfizer’s lack of
promising
Products in its early stage pipeline have left its combined pipeline relatively weaker.
This pipeline Deficit will not manifest for a number of years yet, and Pfizer is
perhaps well positioned than Most to ensure that it balances its R&D pipeline before
it becomes a cause for concern in future.
Pfizer’s imbalanced geographical presence (the US accounts for over 60% of
Pfizer’s market Area) may cause potential geographic limitations and can limit
revenue growth should US Demand weakens.
While the numbers of co-marketing and collaborative agreements, which Pfizer has
established, Are currently proving very favorable, agreements that geographically
limit Pfizer’s activities will Ultimately reduce its long term potential and must be
guarded against.
Finally, the economic emergence of mass production economies like India and
China into the Pharmaceutical fray will require new containment strategies. While
this is not an immediate Threat, over time the nature of competition will change and
the big pharmaceutical firms must Develop strategies to enable them reduce threats
and seize the opportunities that are created in Increasingly integrated global markets.
Going forwards, I recommend that Pfizer actions a resource\competence based
analysis of it’s Innate capabilities, those characteristics that offer Pfizer distinct
competitive advantage over its Industry rivals. There may be a role for using
‘McKinsey’s 7S Framework’ to determine the firm’s Core advantages.
On the period of internship I observed Job Descriptions and Responsibilities of the
Employees were Multi-tasking. The environment of the workplace is entirely
different From the concepts which I studied in books. So I found that to survive in
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the cut-throat Competitive era we need to develop multi-tasking skills along with
dynamic personality And strong communication skills.
Conclusion
The Pharmaceutical industry has a lot of yet untapped potential and it will be
interesting to see How the industry matures over the long term. Undoubtedly, the
long history and global expertise Of firms like Pfizer, GSK and Merck will stand
them in good stated to create and benefit from Emerging global opportunities.
Notwithstanding its strengths, complacency must be guarded Against because
smaller, agile and innovative firms are on the prowl and all it takes for the small
Upstarts are a Superdrug that can change the entire face of the industry. We’ve seen
it in happen In the Information & Communications industry, for all we know
pharmaceuticals may just be Next.
Recommendations
There are few recommendations from my side which can be beneficial for the
company
Employees should be trained according to the changing standards of the
Organization.
Company should conduct survey from time to time according to which
changes can
Be introduced in the organization to stay updated in the market.
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They should introduce creativity into the work, so that the employees can do
their Work passionately.
Employees should be more involved in decision making to become more
Differentiated.
Leanings from IP:
Learning beyond classroom
Platform for implementing theoretical concepts
Exposure to corporate culture
Experience under belt
Insight of actual strengths and weaknesses
Developing a network
Refinement of Career goals
Soft skill development
Impart Winning Edge
Feather in the cap as PPO