Introducing Intuvo 9000 GC System€¦ · Introducing Intuvo 9000 GC System • A completely re-imagined integrated system of GC consumables, MS services and software • New paradigm

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Introducing Intuvo 9000 GC System

• A completely re-imagined

integrated system of GC

consumables, MS

services and software

• New paradigm streamlining

the way GC is done

• Better Business Outcome

• Easier

• Faster

• Smaller

• Smarter

• Greener

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Innovating a New Path to GC Productivity

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Direct

heating

A whole new way to GC


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No-trim

column

Direct

heating



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No-trim

column

Direct

heating



Ferrule-free click-and-run

connections

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Disposable

Guard chip

No-trim

column

Direct

heating




connections

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Disposable

Guard chip

No-trim

column

Direct

heating

Modular

Intuvo flow chips A whole new way to GC



connections

Flexible Compatible Design Configurable to any application

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• SSL, MMI, GSV, LSV inlets

• FID, TCD, ECD, NPD, FPD,

NCD, SCD detectors

• SQ and TQ mass spectrometers

• Headspace, thermal desorption,

purge and trap samplers

• 16-, 50-, 150-position

auto-injectors and trays

Seamless Method Migration to Intuvo Preserving method and SOP investments

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1x10

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+ TIC Scan 12 CAL 10 (20000 ppb) - Apr 30.d

Counts (%) vs. Acquisition Time (min)

4 4.5 5 5.5 6 6.5 7 7.5 8 8.5 9 9.5 10 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5 18 18.5 19 19.5 20 20.5 21 21.5 22 22.5 23 23.5 24

1x10

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+ TIC Scan 12 Cal-10 (Dec 10) 20000 ppb .D


4 4.5 5 5.5 6 6.5 7 7.5 8 8.5 9 9.5 10 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5 18 18.5 19 19.5 20 20.5 21 21.5 22 22.5 23 23.5 24

83 SVOC by US EPA 8270

1x10

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+ TIC Scan 12 Cal-10 (Dec 10) 20000 ppb .D


4 4.5 5 5.5 6 6.5 7 7.5 8 8.5 9 9.5 10 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5 18 18.5 19 19.5 20 20.5 21 21.5 22 22.5 23 23.5 24

1x10

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+ TIC Scan 12 CAL 10 (20000 ppb) - Apr 30.d


4 4.5 5 5.5 6 6.5 7 7.5 8 8.5 9 9.5 10 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5 18 18.5 19 19.5 20 20.5 21 21.5 22 22.5 23 23.5 24

Seamless Method Migration to Intuvo No business disruption

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Intuvo

7890

83 SVOC by US EPA 8270

Innovating the GC Flow Path

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To detector

Conventional

flow path

Inlet

Gold seal

Nuts and ferrules

Classic capillary

column


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To detector

Conventional

flow path

Intuvo

flow path

Inlet Inlet

Guard chip

Gold seal

Nuts and ferrules

Classic capillary

column


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Click-and-run

direct

connections

To detector

To detector

Conventional

flow path

Intuvo

flow path

Inlet Inlet

Guard chip

Intuvo planar

column

Gold seal

Nuts and ferrules

Classic capillary

column

Flow

chip

Click-and-Run Direct Connections Eliminating connection uncertainty

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• No more ferrules

• Direct face seal connections

• Audible and tactile click lets

you know connection is made

• Easier to train

• Less unplanned downtime

• Fewer batch reruns and

precious samples lost

A New Portfolio of GC Consumables

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UI Inlet Liners Guard Chip

No-trim

column

Intuvo

Flow

Chips

Smart Keys

Tools &

Accessories

Intuvo Flow Chips

July 10, 2017

Confidentiality Label

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• Modular microfluidic

chips

• Configures flow path from

inlet to detector

• Provides ferrule-free

connections

• Volumes, restrictions and

flow rates are known

precisely eliminating the

need for complicated flow

calculators

Flow Chips

Inlet

Connections*

connect

guard chip column

Split flow from guard chip two columns

CFT Connections**

Mid-column backflush

Post column backflush

Detector Connections*

Connect column GC detector(s)

Connect column MS

Split column flow multiple detectors

Detector “Tails” * Detector-specific flow

path

*- minimum requirement

**- optional accessory

Autonomous Leak Checking Avoiding unplanned downtime

Microfluidic-enabled 6th generation EPC modules allow hands-free leak

checking to confirm and document leak-free operation autonomously.

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Fast Direct Heating and Cooling Every single minute counts

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• Fast, efficient heating

• Ballistic cooling

• Smaller footprint

“We are the police – we need answers

fast. Even 1 minute faster cool-down

would be valuable…”

Ultra Fast GC It’s All About How Well You GC Fast

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min 0 0.5 1 1.5 2 2.5

pA

0

500

1000

1500

2000

2500

3000

C5

C6

C7 C8 C9

C10

C11

C12

C14

C15

C16

C17

C18

C20 C24 C28 C32 C36 C40 C44

5 replicate overlay of ASTM D7798 SimDist standard mix

Recovery

C5 0.9

C6 0.9

C7 1.0

C8 1.0

C9 1.0

C10 1.0

C11 1.0

C12 1.0

C14 1.0

C15 1.0

C16 1.0

C17 1.0

C18 1.0

C20 1.0

C24 1.0

C28 1.0

C32 1.0

C36 1.0

C40 1.0

C44 0.9

• Excellent retention time and

area count reproducibility

• No concern for cold spots

Efficient, Even Direct Heating

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0.00

0.50

1.00

1.50

2.00

2.50

0 10 20 30 40 50 60 70 80

Rela

tive

Resp

on

se

Compound Number

7890Intuvo

Benzo[b]fluouranthene

Benzo[k]fluoranthene

Benzo[a]pyrene

Perylene-d12(ISTD)

Indeno[1,2,3-cd]pyrene

Dibenz[a,h]anthracene

Benzo[ghi]perylene

0

20

40

60

80

100

120

17 18 19 20 21 22 23

PAHs0.098ug/mL9000/5977A(scan)

High molecular

weight PAH

compounds also

have largely identical

response factors

Even high molecular

weight compounds such

as Benzo(ghi)perylene

(mol wt 276 amu) have

excellent peak shape

Optimizing Lab Space Supporting lean laboratory thinking

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Less than half:

• Power consumption

• Heat output into laboratory

• Laboratory bench footprint

• Lower operating costs

• Higher efficiency

• Greener

Modular Intuvo Flow Chips High purity inert silica flow path

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• Inert

• Modular, configurable

• Click-and-run connections

Intuvo Flow Chip

cross section

Thermally conductive

proprietary alloy

High purity

silica channel

Intuvo ultra inert

treatment

Carrier

gas

Intuvo Inert Flow Path Optimized for active compounds

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5 ppb Injection of pesticide mix

TQ MRM Transitions Chrysene-d12

EPN

Pyroclostrobin

Perylene-d12

Phosalone

Coumaphos

Agilent 7000 TQ/MS

Intuvo Guard Chip and No-trim Columns Running more, maintaining less

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• Simple disposable design

• No column trimming

• Retention time reproducibility

• Less maintenance time

• Less recalibration and

requalification

• Less unplanned downtime

Intuvo Guard Chip and No-trim Columns No retention time shifts after maintenance

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0.5 min

Shifts beyond

retention time

window

Pesticide mix injected before and

after 300 mm column trim

0.5 min

Maintaining

retention times

Pesticide mix injected before and

after guard chip change

Conventional Column Intuvo Column

Intuvo Guard Chip Protect, don’t repair

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• US EPA 8270D SVOC in soil

• Tailing factor slowly increases

during 240 soil extract

injections

• Guard chip replacement

restores analytical

performance and

extends column life

EPATailngFactorLimit

0.0

0.5

1.0

1.5

2.0

2.5

0 50 100 150 200 250 300 350 400

TailingFactor

NumberofMatrixInjections

BenzidineChange guard chip:

No clipping

Intuvo Columns Maintain Integrity

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Example

• US EPA 8270D SVOC in soil

• 30-m columns

• Conventional column clipped

0.3-m every second day:

Lasted 4 weeks

• Intuvo guard chip replaced every

second day:

Lasted 6 weeks

• No trimming, fewer column

replacements, fewer

recalibrations:

3x less maintenance

Intuvo Smart Keys Self aware

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• Flow Chips and Columns

• Smart: Informs how Intuvo is

configured

• Easy: Sets method context and

parameter defaults – no

complex calculators needed

Accessing the Power of Innovation Transforming the user experience

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New mobilized generation

• Expectations of remote mobile

connection

• Technology accessed through

interactive graphic SW and

apps

Make technology accessible

• Interface meeting today’s

expectations

Intuvo Graphical User Interface

• System status

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• System status

• Real-time

chromatograms

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min.0.6 0.8 1.0 1.2 1.4 1.6 1.8

pA

0

500

1000

1500

2000

2500

3000


• System status

• Real-time

chromatograms

• Step-by-step user

maintenance and

troubleshooting

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• System status

• Real-time

chromatograms

• Step-by-step user

maintenance and

troubleshooting

• Finding parts fast

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ReplaceInletLiner

FindInletParts

InletLinerPartNumber8001-

0101

Internet of Things A full suite of customer support

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• Intuvo serves up a web

homepage

• User help for

Maintenance,

troubleshooting and

diagnostics

• Accessible through any

approved PC or mobile

device securely on

internal network

Keep Connected Tablet or phone connectivity

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Go Mobile

Check instrument and batch

status remotely

Confirm laboratory operations

while out of the laboratory

Connect to any instrument with

a single mobile device

Intuvo Graphical User Interface Interactive maintenance

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Remove lock nut and septum

Replace liner

Step 1: Remove lock nut

A Gateway of Information at Your Fingertips Whenever and wherever you are

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• On-line

resources

• Agilent University

• YouTube

• Agilent.com

• Agilent GC

community

Agilent CrossLab Services for Intuvo A streamlined service experience

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Intuvo 9000 GC Health Report

Installation and familiarization

Compliance services

Education

An Ideal Partner for Mass Spectrometry

• Guard chip protection of

column and MS ion source

• Retention time stability after

changing guard chip

• Easy and reliable backflush

• Leak-free click-and-run

connections

• Fast direct heating and cooling

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Intuvo 9000 GC System Appealing to all stakeholders

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Operator and Scientist

• Simpler operation, less training, fewer mistakes

• Innovative enabling technology: Future of GC

Lab Manager

• Less unplanned downtime and disruption

• Delivering results with confidence

Business Executive

• A better financial return on innovation

• Improved operations and business continuity

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Documents

Introducing Intuvo 9000 GC System€¦ · Introducing Intuvo 9000 GC System • A completely re-imagined integrated system of GC consumables, MS services and software • New paradigm