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Jornada sobre INVESTIGACIÓN CLÍNICA EN PEDIATRÍA
Cristina CalvoHospital Universitario La Paz
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INDEX 1. Research structure
1. Clinical Trials Unit
2. Pediatric ResearchGroups
2. Research Networks
RESEARCH STRUCTURE
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CLINICAL TRIALS UNIT (UCICEC)
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LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC)
DIRECTORY ON PEDIATRIC RESEARCH UNITS
2º FLOOR Mother & child hospital.
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LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC)Areas of Pediatric Clinical Trials Alberto Borobia
Clinical Pharmacologist• Allergy• Anesthesia and Resuscitation• Clinical Pharmacology• Biochemistry• Cardiology• Children's Cardiology• Cardiac surgery for children• General Surgery• Maxillofacial Surgery• Orthopedic Surgery and Traumatology• Pediatric surgery• Pediatric Intensive Care• Dermatology• Digestive / Gastroenterology• Endocrinology• Nursing• Pharmacy• Clinical Pharmacology• Gynecology• Pediatric Hemato-oncology• Hematology• Hepatology• Pediatric Infectious-Tropical Diseases and Vaccines• Immunology
• Immunology• Medical and Molecular Genetic Institute• Internal Medicine• Microbiology• Nephrology• Neonatology• Pneumology• Neurology• Child nutrition• Obstetrics / Gynecology• Ophthalmology• Oncology• General Pediatrics• Psychiatry• Radiology• Rehabilitation• Rheumatology• Traumatology• Childhood Pain Unit• Electrophysiology Sleep Unit• HIV Unit• Pediatric Emergencies
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LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC)
FACILITIES
8 beds2 simultaneous admissions phase I.
Personnel trained in Advance Life Support
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20 Physicians in the dayshift, 10 of themalso make guards (24-hour shift)
15 Nurses of pediatric hospitalizationplants accustomed to the management ofchildren, distributed among all shifts and allspecialties. At least 1 nurse per specialtyand shift.
In morning shifts, 6 nurses participating inCT are also added from the externalconsultations of the pediatric specialties
LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC)
PERSONNEL
UCICEC PEDIATRIC UNITS
Permanent: 6Non-permanent: 7Partial time: 15
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14 CT in Phase 1 with evaluation PK/PD
7 CT Phase I-II in which blood samples areprocessed for cell immunity
LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC)
SUBJECTS & PATIENTS
POPULATION PHARMACODYNAMIC / PHARMACOKINETIC
Healthy volunteers Patients Adopters, inmigrants and
refugees Tertiary reference center
of all especialities.
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LA PAZ: PEDIATRIC CLINICAL TRIAL UNIT (UCICEC)
EXPERIENCE (5 LAST YEARS)
Phase
Number of studies I II III IV Observational Individual research
Pharmaceutical company 10 47 142 32 141
Independent group 4 12 22 20 159
AREAS & RESEARCH GROUPS
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PEDIATRIC RESEARCH GROUPS INFECCIOUS DISEASES & IMMUNITY AREA
PATOLOGÍA INFECCIOSA RESPIRATORIA, SISTÉMICA Y NEUROLÓGICA EN LA INFANCIA, Y RESPUESTA INMUNOLÓGICA DEL HUÉSPEDCristina Calvo Rey
INFECCIONES SISTÉMICAS EN PEDIATRÍA; VIH, TUBERCULOSIS, PATOLOGÍA IMPORTADA Y ENFERMEDADES EMERGENTESMaría José Mellado Peña
INVESTIGACIÓN TRASLACIONAL EN CÁNCER INFANTIL, TRASPLANTE HEMATOPOYÉTICO Y TERAPIA CELULARAntonio Pérez Martínez
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PEDIATRIC RESEARCH GROUPSPATHOLOGY OF LARGE SYSTEMS
NEONATOLOGÍAAdelina Pellicer
HEPATOLOGÍA MOLECULARPaloma Jara Vega
CIRUGÍA DE MALFORMACIONES CONGÉNITASLeopoldo Martínez Martínez
TRASPLANTESFrancisco Hernandez Oliveros
SURGERY, TRANSPLANTATION AND HEALTH TECHNOLOGY
Networks
European Reference Network in Pediatric Transplantation
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TRASPLANTCHILD
Facilitating patient empowerment
Health Care Improvement
Improvement of the results of the procedures and the quality of life (clinical guidelines).
Identify areas of research and innovation
Spread Knowledge
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IDIPAZ FOUNDATION
EXECUTIVE COMMITTEE
HOSPITAL UNIVERSITARIO 12
DE OCTUBREDaniel Blázquez
HOSPITALUNIVERSITARIO Y
POLITÉCNICO LA FEEduardo Montesinos
HOSPITAL INFANTIL UNIVERSITARIO
NIÑO JESÚSLucas Moreno
HOSPITAL UNIVERSITARIO VALL D’HEBRONCarlos Rodrigo
HOSPITAL UNIVERSITARIO LA
PAZJosé Luis Narro
THEMATIC NETWORKS
CLINICAL LEADERS OF CONSOLIDATED/THEMATIC CENTRES
GENERAL COORDINATOR
Federico Martinón
HOSPITAL SANT JOAN DE DÉU
Joana Claverol
HOSPITAL CLÍNICO UNIVERSITARIO DE
SANTIAGO DE COMPOSTELA
María Gómez Reino
RED DE INVESTIGACIÓN
TRALACIONAL EN INFECTOLOGÍA
PEDIÁTRICA (RITIP)
Cristina Calvo
RED DE SALUD MATERNO INFANTIL Y DESARROLLO (SAMID)Fernando Cabañas
MANAGEMENT LEADERS
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SAMID NETWORK
RETICS financiada por el PN I+D+I 2013-2016, ISCIII - Subdirección General de Evaluación y Fomento de la Investigación y el Fondo Europeo de Desarrollo Regional (FEDER), ref. RD16/0022.
Maximo Vento &Fernando Cabañas
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SAMID NETWORK
Fernando Cabañas
Leopoldo Martínez
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RITIP NETWORKTraslational Research Network in Pediatric Infectious Diseases
Cristina Calvo &Federico Martinón
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RITIP NETWORK
Cristina Calvo
Mª José Mellado
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TEDDY networkTask-force in Europe for Drug Development for the Young
Mª José Mellado
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TEDDY networkTask-force in Europe for Drug Development for the Young
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Working in GroupWorking in NetworkWorking in Europe
THANK YOU
