tlie

U . S . DEPARTM ENT 0 1' H EALTH. EDUCATIO N . AN O W ll!:Ll'Al'U:

July 12, 1978 Vol. XXX, No. 14

Dr. Emilie Black Named NIGMS Ass't Director For Clinical Research

Dr. Emilie A. Black has been named assistant director for Clini­cal Research in the National Insti­tute of General Medical Sciences. She previou!ly served as director of the Institutl''s Clinical and Psy­chological Sciences Program.

Dr. Black joined NlGMS in De­cember 1968 as program adminis-

In addition to her other duties, Dr. Black will continue to administer N ICMS's research offorts in anesthesi­ology and burn, and trauma.

trator of Clinical ScienccH, Re­,.earch Grants Branch, and has since held positions as acting execu­tive secretary, General Medical Sci­ences Program P roject Committee, and as assistant chief for RGB Clinical Programs.

In her new position, she will serve as staff expert and advisor for clinically related activities to D r. Ruth L. Kirschstein, NIGMS Director.

She received her B.S. and )f.D. dt'srrees from George Washington l'niversity. Following an intern­ship and residency in internal med­icine at Garfield Hospital, she servt'd a residency in pediatrics at the D.C. Children's Hospital during which time she worked on the rick­<>lt.~ial viru,.es, especially Rocky Mountain spotted fever virus, and the use of broad spectrum antibi­otics.

From 1949 to 1966, while in private pediatric practice in the Bethesda area, Dr. Black l<crved concurrently as a medical officer

(See DR. BLACK, Page 1.1)

Clinical Nutrition Conference: A Projection for the l 980's

By Tom Flnin and Julie Klug

Participants in the Biomedical and Behavior al BaRis of Clinical Nutri­tion Conference affirmed the need for new knowledge concerning nutri­tion, as well us for program!; designed to promote public education in nutrition.

Cited as the brj!',crest supporter of nutrition research in the country, NIH hosted the national conference on June 19-20 with participants from other Federal agcndes and departments, academic authorities

Dr. Fredrickson Member Of Delegation to China

Dr. Donald S. Fredrickson, NIH Director, wa!; one of the high-level delegation of 11 ~t"ientists who flew to China for talks on science and technology.

H1•urled by Dr. Frank Press, President Carter's science advisor, the delegation wa!; in Pekini: from July Ii to 10.

The mission's four basic pur ­poses, according- to officials, was to e~tablish offit"ial i-ontacts in science and technolo,n•; to explain the C.S. Government'i; ~ience policy; to as­s1•PS China's pre~ent state of sci­ence and technology; and to sug­gest ways of expanding exchanges.

Contacts in areas of interest to the C'hinese agriculturl', enerey, and medical research, for example -were stressed.

on nutrition, and two outstanding paneh, one on consumer affairs, the other composed of Congre~sional staff.

Dr. Donald S. Fredrickson, NI H Director, greeted the particip1rnts and some 600 attendees of the con­ference, which was sponsored by the NIH Kutrition Coordinating Committee.

Noting improper nutrition as being directly linked to 6 of the 10 leading cause~ of death, Hale Champion, Under Secretary of HEW, spoke for HEW Secretary Joseph A. Califano, Jr.

Further introductory remarks addressing the potential of clinical nutrition were given by Or. Julius Richmond. R EW Assistant Secre­tary for Health. Dr. Artemis P . Simopoulos, NCC vice chairman and execut ive secretary, presented tho NIH program in clinical nutri­lion research, and Dr. S1•ymour Perry, NCC chairman, introduced and chaired the six scientific panels on .June 19.

(Continued 011. Page 8)

Among those participati1tg in the Clinical Nutrition Confe rence were Cleft to right I: Dr. Simopoulos; Dr. E. H. Ahrens , Jr. , Rockefeller University ; Dr. Dubos; Dr. Corald Caull, New York State Institute for Basic Research in Me1ttal Retardation ; Dr. Fredrickson; and Dr. Jules Hirsch, Rockefeller University.

NAT IO NAL I NSTITUTll!:8 0 1' H EALTH

Dr. Leon Jacobs Selected Director, Fogarty Center

Dr. Jacobs, who hH received several awards for research on toxoplasmosis and other infections, is preside1tt of the American Society of Parasitologists.

Dr. Donald S. Fredrickson, NIH Director, ha.~ announced the selec­tion of o~. Leon Jacobs as Director of the John E. Fogarty I nterna­tional Center for Advanced Study in the Health Sciences.

"I am pleased to announce the selection of Dr. Leon Jacobs as Director of the Center," Dr. Fred­l'il-kson said.

"All of us who have had the good fortune to work with Leon in his prt'sent position-as well as in his previou~ position as Deputy A~,ist­ant Secretary for Science in the Office of the Secretary, HEW­know of his vast knowledge and sage advice."

Established Contract Guidelines

Since 1972 Dr. Jacobs has served as Associate Dir1•etor of Collabora­tive Research in the Office of the Director, KIH, maintaining ~ur­veillance of the NJ 11 contracts pro­gram through the establishment of guidelines for the initiation and review of con tracts.

FIC fosters international cooper­ation and collaboration in the inter­ests of the health of mankind, and was the first Center for advanced study within t he Federal structure.

The Center coordinates intema­(Sce DR. JACOBS, Page ,4)

Page 2 July 12, 1978

ecord P ublished biweekly at Bethesda, Md., by the Editorial Operations Branch, Division of P ublic Information, for the information of employees of the National Institutes of Health, Department of Health, Education, and Welfare, and circulated by r equest to interested writers and to investi­gators in the field of biomedical and related research. The content is reprintable without permission. Pictures are available on request. The NIH R ecord reserves the right to make corrections, changes, or de­letions in submitted copy in conformity with the policies of the paper and the Department of Health, Education, and Welfare.

NIH Record Office . Bldg. 31, Room 2B-03. Phone 496-2125

Editor . . . . . ....... . ... .

Associate Editor

.. Frances W. Davis

. . . . . Heather Banks

Staff Correspondents

ADA, Judy Fouche; CC, Susan Gerhold; DCRT, Mary Hodges; DRG, Sue Meadows; DRR, Jerry Gordon; DRS, Arthur F. Moore; FIC, George Presson; NCI, Dr. Robert M. Hadsell; NEI, Julian Morris; NHLBI, Bill Sanders; NIA, Ann Dieffenbach; NIAID, Jeanne Winnick; NIAMDD, Diane Naedel; NICHD, Tina McIntosh; NIDR, Sue Burroughs; NIEHS, Hugh J . Lee; NIGMS, Wanda Warddell; NIMH, Betty Zubovic; NIN CDS, Carolyn Holstein; NLM, Roger L . Gilkeson.

Personnel Continues Phone Series With Special Theme

The telephone series of re­cordings on personnel topics will be available indefinitely on a 24-hour basis.

To hear topics featuring the theme, Employment Informa­tion and Career Development Opportun ities, call 496-4608 on the dates indicated:

Jvly 10-14-Preparing an Effective SF 171 and Inter­viewing for a Job

July 17-21-Office Skills Ca­reer Development Program

July 24-28-Apprent iceship Program

July 31-Aug. 4-Stride Pro­gram

Aug. 7-11- NIH Manage­ment Intern Program

A Few Concert Series Tickets Available for NIH Newcomers

FAES has withheld a limited number of tickets for the 1978-79 Chamber Music Series to give those NIH Staff Fellows and Clinical Associates arriving after July l an opportunity to subscribe to the con­cert series. Tickets for those eligi­ble will be available now through Aug. 15.

For more information and a sub­scription form, contact the FAES office, Bldg. 10, Rm. Bl-L-101, phone 496-5272.

The Foundation for Advanced Education in the Sciences will pre­sent eight concerts in its 1978-79 Chamber Music Series.

The concert dates are: Oct. 8, 1978-The Cleveland

Quartet with Richard Stolzman Nov. 4, 1978- Virtuosi di Roma Dec. S, 1978-Peter Serkin

FAES Graduate School Fall Semester Courses Listed in New Catalog

The FAES Graduate School at NIH has scheduled its courses for the fall semester. The evening classes sponsored by the Founda­tion for Advanced Education in the Sciences will be given on the NIH campus.

Courses are offered in biochem­istry, biology, genetics, chemistry, physics, mathematics, medicine, physiology, immunology, microbiol­ogy, nursing, psychology, psychia­try, statistics, languages, and ad­ministration, as well as courses of general interest.

It is often possible to transfer credits earned to other institut ions for degree work, and many courses are approved for AMA Category I credit.

Tuition is $26 per credit hour, and courses may be taken for credit or audit. Those students whose ex­penses will be paid by the Govern­ment should apply at once to their administrative offices for training assistance.

Classes will begin Sept. 18, with registration possible by mail now through Aug. 18, and in person from Sept. 13.

Catalogs are available in the FAES office in the Clinical Center, Bldg. 10, Room Bl-L-101. To have one sent, call 496-5272.

Jan. 21, 1979- The Vermeer String Quartet

Feb. 25, 1979-Sylvia Marcovici Mar. 18, 1979-The Trio di Mi­

lano Apr. 8, 1979- Laurence Lesser

and Samuel Sanders Apr. 29, 1979-Rudolf Firkusny

Apprenticeship Training Position Applications Accepted in Late July

Applications will be accepted in late July for the following appren­ticeship positions:

Carpenter E lectrician Painter Plumber Refrigeration and Air Condition­

ing Mechanic Sheet Metal Mechanic Stationary Engineer (Boiler

P lant Operator) There is one apprenticeship posi­

tion for each job listed above except for the last-there are two posi­tions for the Stationary Engineer job .

To be eligible employee must: • Have been employed at J\"'JH

for 1 year as of close of business Aug. 14, 1978;

• Be in a permanent full-time position, or if part-time, be willing to be reassigned to a full-time position; and

• Be in a nonprofessional job series ( one grade promotions).

Refer to the upcoming July 24 NIH Merit Promotion Vacancy Listing on NIH Bulletin Boards or in B/ J/ D pe1·sonnel offices for ap­plication procedures.

Women May Apply

For more information, employees may attend the scheduled question­and-answer session in Wilson Hall, Bldg. 1, on either Wednesday, July 26, at 4 p.m., or Thursday, Aug. 11, at 9 a.m.

Women are encouraged to apply.

Rebecca Wilner has been appointed personnel officer for the Office of the Director, Fogarty International Center and the Office of Administration Per­sonnel Office. She joined the NIH Division of Personnel Management in 1970. Ms. Wilner has worked as a personnel generalist in the personnel offices of the National Eye Institute, the Division of Research Resources, and served as personnel officer for the Division of Research Services. She re­ceived both B.S. and M.A. degrees in public administration from American University.

THE NIB RECORD

Confidential Counseling Is Available to Employees

The issue of confidentiality in counseling is raised repeatedly in reference to the Employee Assist­ance Program. Fear of repercus­sions is one of the major obstacles to seeking counseling.

Information given during the counseling sessions remains totally confidential under all circum­stances.

Jf an employee's job performance deteriorates to the point of super­visory referral t o the EAP, then, of course, such action is docu­mented by the supervisor along with information relating to poor job performance. This documenta­tion is available to the employee, and he/ she may receive copies for his records.

Offer Assistance

The referral is an attempt to offer assistance and is not a disci­plinary action.

For self-referred individuals, confidentiality is strictly respected unless the person wants his or her supervisor to know about the coun­seling and/ or needs time off to attend weekly sessions. Should the latter be the case, a release of in­formation signed by the employee authorizes the counselor to reveal 011/y attendance or outside referral if indicated.

Call 496-2738 for further infor­mation or to make an appointment.

Sign Up for R& W Trip To Orioles/ Yankees Game

See the Baby Birds take on last year's world champions, the Big Bad Yankees, at Mem­orial Stadium, on Monday eve­ning, Aug. 14. Watch your favorites-Reggie, Thurmond, Craig, Willie, and their awe­some pitching staff-take on the surging Oriole team.

Charter Bus Included

Gather your family and friends for an evening of fun in Baltimore: $5.75 includes reserved seats, round trip bus fare, and service charge. Buses will leave Bldg. 31C at 6 :15 p.m. and return following the game.

A limited supply of tickets is available, so hurry- sign up at the R&W Activities Desk in Bldg. 31 NOW!

NIAID Honors Six Employees

Dr. Ken neth Sell, scientific direc­tor of the National Institute of Allergy and Infectious Diseases, re­cently presented 30-year length of service awards to C. Elwood Clag­gett, Dr. Louis S. Diamond, Rod­ney H . Duvall, Louise P. Kendrick, Dr. Eugene C. Weinbach, and Ser­rah C. Wood.

THE NIH RECORD July 12, 1978 Page S

Aid PEF, Win a Prize for Guessing Total Health's Angels 24-Hour Relay Mileage

The NI H Health's Angels will be r unn ing in the Runner's World East Coast 24-Hour Relay Race at Ft. Meade, Md. The NIH team of speedsters is expected to run be­tween 240 and 280 miles-a mile at a time per team member. They w ill run at the r ate of 5 :20 and 6 :00 minutes a mile starting Saturday, Aug. 5, at high noon and finish ing Sunday, Aug. 6, 24 hours later.

TRAINING TIPS The following courses are being

sponsored by the Executive and Management Development Branch in the next 2 months:

Super11isor11 Time Management for Super­

visors-July 11 and 12 Concepts of Classification and

F .E.S.- July 18 and 19 Management of Conflict and

Agreement-July 26-28 Communication Issues- Aug,

7-9 Super visory and Managerial

Effectiveness-Sept. 12-14 M arwge1·ial

Understanding and Managing Stress-Sept. 7 and 8

F or more information call Sace­lia Damuth, 496-6371.

Automated Typewriting Workshops To Be Held

The Graduate School, U.S. De­partment of Agriculture, is now offering daytime workshops in au­tomated typewriting.

Classes -at beginning, intermedi­ate, and advanced levels on mag­netic keyboards include the Mem­ory Typewriter, Mag Card A, and Mag Car II.

The workshops will be helrl in ,July, August, and September. Tui­t ion is $8,5 per course, and includes all books and course materials.

For information and brochures, call 447-7124.

Here's the pitch: For $1 you can guess how far our team will run.

The person with the closest guess to the total number of miles and yards (1760 yards per mile) will receive a $50 U.S. Savings Bond from the R&W Association.

Drop your guess--or guesses--off with a $1 check per guess-in the fish bowls (envelopes provided) at any R&W Gift Shop. Be sure to in­clude name, and NIH Building and Room number. · For the past 2 years Health's

Angels have won individual awards in this national event. Come out and cheer the team on. F ort Meade is off the Baltimore-Washington Parkway on Route 198.

Blood Bank, Red Cross Sponsor Joint Summer Drive at Landow Bldg.

The Clinical Center Blood Bank and the Montgomery County Chap­ter of the American Red Cross are sponsoring a joint summer blood drive on Wednesday, ,J uly 19, from 9 :30 a.m. to 3: 15 p.m. in Confer­ence Room C418/414 of the Landow Bldg., 7910 Woodmont Avenue, Bethesda.

This drive seeks to recruit new blood donors and make it conven­ient for regular hlood donors in the Landow Bldg. to CQntinue their donations.

The blood will be used to support patient care at the CC as well as in the Metropolitan Washing-ton area p/1,s keeping up the Blood Assur­ance Program for NIH employees.

Help make this summer season a safe one for those who need blood. Be a volunteer blood donor at the Landow Bldg.

For information or an appoint­ment, call the CC Blood Bank, Bldg. l0A, Room 1E33, 496-J048 or 1049, between 8 a.m. and 5 p.m., Monday through F r iday.

L to r, Steve Weise and Pat Harwood teamed up in Mixed Doubles to defeat Millie Steckman and Ray Chen.

Finals of the 1978 Spring Tournament were held J11ne 11 on the NIH tennis co11rts. ln a replay of last year's final, James Hamilton (11 defeated Antonio Rene to retain the Men 's "A" Singles title.

David Anderson ( r ) was the Men's " B" Singles Champion with a straight set victory over Ted Breitman.

1978

NIH

Spring

Tennis

Tournament

Finals

In Women's Singles, Nona Rene ( I) had to retire with a 7 - 6 , 2 -0 lead to give the t itle to defending Spring Tournament Champion Bonnie Kal­berer.

L to r, Brad Lindgren and Richard Broadwell , last year's Men's Doubles runners­up, captured first place this time in a three-set victory over Peter Rene and Steve Weise.

From left, Pat Harwood and Flora Feld w ere Women's Doubles Champions over Nancie Doran and Joan Casey.

Page 4 July 12, 1978 THE NIH RECORD

Norman Mills Shows He 'Can Dolt'­Rises From Animal Caretaker to A-. 0.

There are not too many NIH employees around who have started at the GS-~ level and, by dint of self-motivation and sheer persistence, sur­faced with a college degree and an appointment as an administrative officer.

Norman E . Mills, administrative officer of the Division of Research Resources, joined NIH as an ani­mal caretaker in 1955, and was one of the original group of partici­pants in the Stride program launched by NIH in 1972.

Graduated in 1976

He majored in personnel man­agement at American University and says, "It was quite a shock to be competing with men and women 20 to 25 years younger." He com­pleted the course requirements in 3½ years, graduating in 1976-ap­proximately 23 years after receiv­ing his diploma from Cardoza High School.

Although the native-born Wash­ingtonian was offered athletic scholarships as an outstanding swimmer by three colleges upon graduation from high school, he had no interest in higher education at that time.

After working for 2 years as a truck driver, Mr. Mills became a Civil Service employee at NIH as a GS-1 animal caretaker for the Na­tional Institute of Neurological Diseases and Blindness under Dr. Maitland Baldwin, chief of Surgi­cal Neurology.

Did Medical Photography

An amateur photographer, Mr. Mills convinced Dr. Baldwin in 1960 that he was capable of doing medical photography.

He eventually set up a labora­tory in the Bldg. 9 animal area, where he photographed and proc­essed most of the gross histological specimens of chimpanzees and rhesus monkeys. In 1966 he re­ceived a Superior Performance Award for his efforts.

In addition to his photography and laboratory assistant work, the energetic medical biology techni­cian also taught autopsy prepara­tion and embalming procedures to new laboratory employees. In 1970, he became a full-time laboratory photographer for the Institute.

Coordinates Move

He came to DRR in 1973 as a Stride employee participant and, upon receiving his B.S. degree in personnel management from Amer­ican University, was made assist­ant administrative officer in 1976. He subsequently won a Special Achievement Award that same year for his efforts in coordinating a major move of the Division.

On Dec. 4, 1977, Mr. Mills was appointed DRR administrative offi­cer.

A deeply religious man, Mr. Mills is an active member of the

On the way up the career ladder, Mr. Mills performed the duties of a medi­cal photographer as well as a biology technician.

Edward Lambert Retires From Dental Institute

Edward C. Lambert, mechanical engineering- technician, National Institute of Dental Research, re­cently retired after 34 years of Government service.

Mr. Lambert served in the U.S. Navy before joining the Naval Ord­nance Laboratory as an instrument maker in 1948.

He transferred to the Division of Research Services' Laboratory Aids Branch of NIH in 1957, and shortly thereafter was assigned to NIDR where he remained for the balance of his career.

Responsible for Instruments

Responsible for designing and fabricating many special instru­ments for use in the ultrastructure studies of calcified tissues, Mr. Lambert a lso provided assistance to all the laboratories of the Den ta! Institute's Intramural Programs.

Evangel Temple Church. Re re­side_s with his family in Landover, Md., and expects to have both of his daughters in college simultane­ously within a few years.

He still retains his interest in photography and occasionally does some professional work for commu­nity functions.

The 43-year-old administrator says he has acquired a philosophy in recent years which may explain his rise in the NIH ranks. "Think positively," Mr. Mills admonishes.

"Never look down at anybody or anything. Never use the words, 'I can't,' and repeat the following to yourself every day: I can do it . . . I am doing it . . . damn it, it's done!"

NIAID Expands lnternat'I Health Efforts, Seeks To Link U.S., Foreign Investigators

The National Institute of Allergy and Infectious Diseases is expanding its efforts in international health by assisting research centers in devel­oping countries and by encouraging and strengthening scientific linkages between the U .S. and foreign in­vestigators.

These new efforts will consist of two interrelated activities: Inter­national Program Projects Grants and International Exploratory/De­velopmental Research Grants.

The programs will emphasize re­search related t o medical problems important to developing countries. NIAID is interested in research on tropical diseases involving medical protozoology, entomology, helmin­thology, malacology, mycology, vi­rology, and bacteriology.

Emphasise Infectious Diseases

Special attention will be given to infectious diseases, including those emphasized in the WHO Special Program for Research and Train­ing in Tropical Diseases- malaria, schistosomiasis, filariasis, trypano­somiasis, leishmaniasis, and leprosy.

However, the program does not exclude other disease categories equally important to developing countries.

International Program Projects Grants will be aimed at establish-

DR. JACOBS (Continued from Page J)

tional conferences and administers international exchange fellowship, senior international fellowship, and scholars-in-residence programs.

Dr. Jacobs replaces Dr. Milo D. Leavitt, Jr., who has been Director of the Center since 1968. Dr. Leav­itt has assumed duties as assistant for medical program development and evaluation with the National Institute on Aging, carrying out a long-standing desire on his part to become involved in medical pro­grams on aging.

Dr. Leavitt has just returned from an in-depth survey of 10 de­partments of geriatric medicine in the United Kingdom to identify in­stitutions having potential for re­search and postdoctoral opportuni­ties of interest to NIA.

An internationally known para­sitologist, Dr. Jacobs was a re­search parasitolr,gist at NIH, serv­ing as chief of several sections and laboratories from 1956 to 1964.

Held Previous Posts

He was acting scientific director of the National Institute of Allergy and Infectious Diseases for 1 year before becoming scientific director of the Division of Biologics Stand­ards-now the Bureau of Biologics in the Food and Drug Administra­tion.

From 1967 to 1969 he was Dep­uty Assistant Secretary for Science

ing a program in International Collaboration in Infectious Diseases Research that will link u.s·. insti­tut ions to research units at over-seas sites.

These grants, which will replace the current International Centers for Medical Research, focus on in­fectious diseases and the immunol­ogy of those diseases.

A major portion of the research must be conducted in a foreign country, and it must be relevant to one or more important health prob­lems of that country.

Through the International Ex­ploratory/Developmental Research Grants, NIAID will be encouraging additional linkages between U .S. and foreign investigators with com­mon research interests in infectious diseases and immunology.

Considered under this arrange­ment will be receipt of individual research proposals from a U.S. in­vestigator involving collabo·ration with a foreign affiliate at an over­seas site.

Purpo~e of the collaborntion will be to identify and investigate com­mon areas of interest in infectious diseases and the immunology of these diseases. However, these grants are not intended to provide Jong-term support but, rather, to encourage the development of pro­gram project grants.

Prospective applicants for one or both of the International Programs may submit a letter of intent for program information on or before Nov. ), 1978. However, this letter is not a prerequisite to submitting a grant proposal.

Application kits containing a spe­cial format with accompanying in­structions for each of the new pro­grams are available from Dr. Earl S. Beck, NIAID, Room 749, West­wood Bldg., Bethesda, Md. 20014.

Deadline for receipt of proposals has been set for Jan. 15, 1979.

in the Office of t he Secretary, HEW, returning to NIH in 1969 as Assistant Director for Collabo­rative Research. In 1972 he was named Associate Director for such research.

For his studies on toxoplasmosis and other infections, he has re­ceived the Washington Academy of Sciences Award for Scientific Achievement in the Biological Sci­ences, the Arthur S. Flemming Award, and the Henry Baldwin Ward Medal of the American So­ciety of Parasitologists.

Dr. Jacobs received his B.A. de­gree from Brooklyn College and his M.A. and Ph.D. degrees from George Washington University.

THE NIH RECORD

Environmental Chemical Effects on Mother's Milk Will Be Studied

The National Institute of Envi­ronmental Health Sciences, in co­operation with two North Carolina hospitals, has begun the first study of its kind in the United States to determine whether the presence of environmental chemicals in mot h­er's milk has any effects on the growth and development of chil­dren from birth to 6 months.

The 2-year epidemiologic study was developed jointly by Drs. Wal­ter J. Rogan and Beth Gladen of the Biometty Branch along with Dr. James McKinney, head of the Chemistry Section, all at NIEHS.

Earlier studies have found vary­ing amounts of environmental chemicals in the breast milk of U.S. mothers, but whether these chemi­cals, particularly the polychlorin­atcd biphenyls (PCB's), have any effect on nursing children has never been studied directly.

Currently pa rticipating in t he study are Wake Medical Center, Raleigh, and Pitt County Memorial Hospital in Greenville, N.C. A third North Carolina hospital will soon be added.

Each mother who enrolls in the study as a volunteer will initially be interviewed concerning her gen­eral health and eating patterns during pregnancy and asked to sup­ply a sample of the milk or formula that the baby is fed.

Measure Contaminants

Contaminant levels will be meas­ured in placenta, cord blood, and the mother's serum at the time the baby is delivered. The children will be evaluated serially over the first 6 months of life with particular attention paid to their growth and development , and breast milk or formula will be collected.

Prior to leaving the hospital, each infant will be given a Brazel­ton Neonatal Behavior Assessment, and at 6 months, a Bayley Scales of Development will be adminis­tered. Data on bottle fed and breast fed infants will be compared, and dose-response relationships will be estimated.

Data from the study will be ana­lyzed at NIEHS after chemical analyses are performed under con­tracts at laboratories in Wisconsin and California.

Dr. Rogan said, "We know from earlier studies that the milk of mothers in the United States con­tains varying amounts of environ­mental pollutants, including PCB's, DDT, and DDE.

"All of these agents are toxic to some degree. However, there has never been a study designed to compare the amount of such com­pounds ingested by breast fed ba­bies and their bottle fed contempo­raries. Also, the question of trans­placental exposure has not been explored adequately."

J uly 12, 1978 Page 5

Limited Copies Available: Workshop Proceedings On Sugar Substitutes

The proceedings of an interna­tional workshop to evaluate sugar substitutes which do not cause tooth decay are now available.

The conference was supported by a grant from t he National Caries Program of. the National Institute of Dental Research to Dr. James H. Shaw of the H arvard School of Dental Medicine.

Reconu11e11d Future Research

After 23 scientific reports were presented and discussed--on sub­jects ranging from the role of sugar in nuttition and tooth decay, and sweet perception and its influ­ence on food selection, to SUj!"ar 's varied uses in commercial food preparation and the economics of the international sugar market­the participants formed task forces and made recommendations for fu­ture research and action.

Publish Consensus

The published recommendations represent the consensus of the task forces, mad~ up of participants from Government, industry, and health and research groups. The diversity of backgrounds meant that not all recommendations were unanimous.

The recommendations included: • That snack foods manufactured

with suga,· content carry a warn­ing label stating that frequent use of the product between meals may be detrimental to dental health

• That food and beverage labels should state the total amount of sugar in the product

• That research be conducted to identify the most cariogenic foods and ways to reformulate them to reduce cariogenicity

• That the food industry develop noncariogenic snacks

• That nutrition counseling and other techniques be tested to see how they affect eating patterns and tooth decay incidence

• That studies be undertaken on mechanisms of sweet taste and per­ception

• That a test system be devel­oped for determininl!' cariogenicity more quickly and reliably than ani­mal tests now used.

The proceedings, edited by Dr. Shaw of Harvard and Dr. Gerassi­mos G. Roussos of NIDR, appeared as a special supplement to the Feeding, W eight, and Obesity Ab­stracts.

A limited number of copies are available from the NIDR Office of Scientific and Health Reports. In quantity, the book can be pur­chased for $15 a copy from Infor­mation Retrieval , Inc., 1911 Jeffer­son Davis Highway, Arlington, Va. 222.02.

Two NCI Staff Groups Receive Awards For Extraordinary Service and Support

L to r, front row: NCI de puty director Dr. Guy R. New ell ; NCI Director Dr. Arthur C. Upton; and acting associate director, OIA , Dr. Gregory T . O'Conor. Back row, I to r, ICRDB awardees : Mary Cinkan, Elaine Campbell , Kathleen McManus, Donna Wicker, Dr. Dianne Tingley, Richard Amacher, with Dr. John Schne ider, ICRDB director. Als , receiving awards, but not present, w ere Samue l Tancredi and Barry Goldfarb.

NCI Directo1· D1·. Arthur C. Up­ton recently presented group cash awards at two ceremonies honor­ing the staffs of the International Cancer Research Data Bank and the Mail and Files Unit, both in the Office of the Director, National Cancer Institute.

3 - Year Effort Cited

The nine recipients of the ICRDB award were cited for the extraor­dinary amount of work performed for the 3-year period from April 1, 1974, shortly after the ICRDB was established and placed in the Office of International Affairs.

"The high level of performance required for this rapid initial im­plementation of the ICRDB plans by a very small staff was an out­standing accomplishment which significantly exceeded expectations and normal work loads.

Praises Dedication

"I wholeheartedly support and recommend this cash award to a dedicated and effective cadre of outstanding NCI employees,'' Dr. Gregory T. O'Conor, associate di­rector for International A ff airs and di rector of the Division of Cancer Cause and Prevention, wrote in his

recommendation for the award. The ICRDB's primary objective

is to promote the exchange of in­formation on cancer research throughout the world.

The statement in support of the group award to six members of the Bldg. 31 Mail and Files Unit pointed out that there had been a "dramatic increase in workload" since 1974, often requiring long hours of overtime.

Often Work Overtime

"Despite the fact that no addi­tional positions have been allocated to this unit, the group of six em­ployees has managed to keep pace with daily mail deliveries, classify­ing of materials, and filing re­quests. They have worked overtime many evenings and weekends to prevent a filing backlog, often at a sacrifice of their personal plans," NCI administrative officer Thomas L. Kearns said in the awards state­ment.

Others Also Complime nt

He also cited the many compli­ments the Mail and Files Unit has received from other NCI offices , attesting to the unit's reliability and efficiency.

Front row , I to r: Calvin B. Baldwin, NCI executive officer, and NCI Director Dr. A rthur C. Upton. Back row, J to r, Mail and Files awardees: Ceorge Miller, Mary Goins, Ele nora Barnett, Juanita Standard, Allison Lum, and James Ridgely, su pervisor.

Page 6 THE NIB RECORD

SUMMER COMES TO NIH • • • By Lisa Carrigan

Have you noticed some new faces lately? Probably, because NIH employs approximately 700 young people in t he Summer Employment Program. Different criteria are used to select participants in nine separate youth programs.

Summer employment at NIH is designed to give young adults valuable experience as well as a chance t o learn about Government activi­ties.

According to Joyce Schools, NIH Summer Employment coordinator, approximately 4,000 applications were received for 700 summer em­ployment positions this year. Science-related jobs are t he most sought after, and the ratio of applications received is large.

Recent policy has emphasized hiring minor­ity, disadvantaged, and handicapped st udents.

The process of procuring summer employ­ment by the Federal Government begins during the early part of the year.

Occasionally students wander into the NIH employment office in J une and ask for a sum­mer job. They are told to try again next year and not to miss any deadlines.

Procedures for the Federal Summer Intern­ship Program begin in November. Colleges and universities have until Nov. 5 to respond if t hey are interested in participating.

The name of the school is then placed on a list. Government agencies, departments, and branches choose schools from which they would like to receive applications. Not just any stu­dent in a chosen school may submit an applica-

Jody Hochberg agonises over the mailbox, checking to see if his rejection or acceptance notice has yet been delivered. For the past 2 summers he has received acceptance notices. A graduate student from N.Y. Stale University, working under Dr. Ted Theodore of NIAID, he is labeling compounds which cross cell membranes. "The job I have now is exactly what I want to be doing when I have finished with my education," he says.

tion. Applicants are normally matched to jobs which will give t hem exper ience in their major fields.

During J anuary a special nominating com­mittee or board selects two nominees. E ach university or school may use its own nominat,. ing procedures.

The names of the nominees and other perti­nent data are forwarded to t he agency or office where a summer Job is available in the nomi­nee's major field. The decisions are made in the spring.

For another program, t he Civil Ser vice Sum­mer E mployment Examination applicants must file by Jan. 27 and take t he test on a specified Saturday in February. Candidates must score above 70 to be considered for employment.

Students wishing to be employed at NIH must send an application along with the test scores directly to the NIH personnel office. Here the student's name is placed on a roster according to his/ her score on the Summer Em­p loyment Examination. Clerical positions are filled from this list.

Some of this year's NIH summer e mployees demon­strate many of the necessary ste ps an applicant must take before gaining e mployme nt at NIH. Here, Federal Summer Intern Lisa Carrigan circles a deadline on the calendar. Most of the summer jobs require that early deadlines be met. Ms. Car­rigan is a junior at The Ceorge Washington Uni­versity. Presently she is working in the Office of Communications, 00.

Doria Law (I) and Craig Sakai, both sophomores at the University of Maryland, say it's easy to get lost on one's first day of work. Mr. Sakai is majoring in biochemistry, and Ms. Law's field is biology. Both work for NEI as clerk typists. Last yea r Ms. Law wanted to work for the Federal Covernment, but she took the wrong test. This year she took the Summer Employment Examination and was called for a job while she was studying for final exams.

!I

After finding the right place, more forms must be filled out. Joyce Schools, the Summer Employment coordinator (I ) , hands focelyn De Laine some NIH literature. Ms. Delaine, who attends the University of the District of Columbia, is majoring in special education. She is a clerk typist in the Stay-in­School program.

Photos by Heather Banks

July 12, 1978 Page 7

BRINGING 700 NEWCOMERS

I

Transportation is needed, so Shauna Johnson (I) and Jacqueline Taylor (r) check the carpool loca­tor board. Both are Stay-in-School students work­ing in the Photo Services department as photo assistants. Ms. Johnson is majoring in media tech­nology at the University of the District of Colum­bia. Ms. Taylor is a Howard University student majoring in physical therapy.

A program for professional school students, the Commissioned Officers Student Training Extern Program (COSTEP) is a year-round program, with three time segments in which a student can gain experience in his/her field.

The summer portion, May through August, requires applications to be in by Feb. 1. The September to December segment has a May 1 deadline; and for January to April, Oct. 1 is the deadline.

This summer more than 475 students have been placed across the country in various PHS divisions. In the past, more than 14 percent of the summer COSTEP employees have returned to PHS work upon graduation from profes­sional school. Students from medical, dental, and veterinary schools are accepted as well as students who have completed 2 years of study in pharmacy, therapy, dietetics, nursing, sani­tary ~cience, medical records administration, or engineering. Also, students enrolled in mas­ters or doctoral programs in health-related fields are eligible for COSTEP.

Approximately 100 COSTEP students are employed at NIH this summer.

Filling out SF-171 is a project for a long a~er­noon. /on Meisner, a senior physics major at Yale University, is now working under Dr. William Hagins in NIAMDD on vision oriented research. This is his fifth summer working at NIH. "I've learned as much working here as I have in any of the classes I've taken at school," he says.

Settling in to do some research is COSTEP em­ployee Michael Neremberg. After completing his first year at Yale University School of Medicine , Mr. Nere mberg is working with Dr. Alfred Singer of NCI observing immune cell inte ractions in anti­body production. A native of Wilmette, Ill. , he did his undergraduate work at The University of Chi­cago. This is his first summer at NIH.

The Stay-in-School Program assists many Washington area students in continuing their education by allowing them to work 16 hours per week during the school year and full time in t he summer. Many students between 16-21 start as summer aids and become Stay-in­School employees during the school year.

The Junior Fellowship P rogram is comprised of students who are graduating from high school in the spring. Once selected, the fellows can continue their summer employment in sub­sequent summers, rotating to different agencies each year.

The Graduate Program is an aid for recruit­ing temporary, professional full-time employ­ee.;. Positions in this program arc in scientific or analytical areas.

The Handicapped Students Program provides job, for the mentally retarded or severely han­dicapped students. They hold positions in cleri­cal, technical, or professional areas.

Senior high school students are eligible to work at NIH through a program administered by American University. NIH selects students from a list of eligibles compiled by American University. The program is financed by con­tributions from the Washing-ton Academy of Sciences, the National Space Club, and the Chemical Society of Washington.

All of the programs for summer employment are intended to educate students and offer them experience they could not find in a classroom.

Marilyn Yick works in the personnel office as a clerk typist Stay-in-School student. Ms. Yick has just graduated from Woodrow Wilson High School and will attend The George W ashington University in the fall. From her part- time experience at NIH during the· school year, Ms. Yick says, " I've learned how things operate in a Government agency."

Page 8 July 12, 1978

CLINICAL NUTRITION CONFERENCE PROJECTION (Continued from, Page 1)

Dr. J . Michael McGinnis, HEW Deputy Assistant Secretary for Health and chairman of the HEW Nutrition Coordinating Committee, chaired the second day's proceed­ings on the Federal, Congressional, and Consumer Aspects of Nutrition Research and Education.

Concur in Need for Studies

As a Projection for the 1980's, the subtitle of the conference, the participants concurred that the greatest promise for solution to nutrition-related diseases and im­proved health will be in fundamen­tal studies concerning t he absorp­tion, metabolism, and mechanism of action of nutritional factors, the biological control of such processes, and the identification of as yet un­known nutrients and their metabo­lites.

Of equal importance will be in­vestigations into the interaction of nutrition with stress, disease, hor­mones, imbalance of nutrients, drugs, and other environmental factors.

Members of the consumer panel challenged the role of the scientific community in raising the "QI"­questioning intellect--of the Amer­ican public about nutrition.

Billions Spent on Advertising

They noted the billions of dollars spent on food advertising and the attendant "misnutrition" as well as malnutrition evident in the U.S.

Consumers should have an input in determining nutrition research priorities, but they must not forget that nutrition is a complex and dif­ficult science, cautioned Kristen McNutt of the Senate Committee on Agriculture, Nutrition, and Forestry.

Johanna Dwyer, Director of the Francis Stern Nutrition Center, chided the bench scientists for adopting attitudes ranging from intellectual humility ("we don't know anything") to superior under­standing ("too difficult to explain").

They should rather adopt a "tell it like it is" attitude, educating the consumer and involving him in the research process ("here's what we know, here's what we don't know").

Amplify Con$umer Ideas

Chaired by Chris Hitt of the Sen­ate Nutrition Subcommittee, the Congressional staff panel amplified the thoughts of the consumer advo­cates. Scientists have the option of becoming more involved in educat­ing and informing Congress and the public how nutrition research dollars are spent and what should be established as nutrition research goals and priorities.

Failing that option, the federally­supported scientific community may find itself with dwindling influence on the future direction of nutrition

research. Present research as reviewed by

the six panels covered the evolvin g concepts of clinical nutrition.

Significant developments in the area of genetic disease and nutrient interaction include elucidation of the defect in the control mecha­n isms regulating cholesterol bio­synthesis in familial hypercholes­terolemia, defects of transport mechanisms resulting in a higher than normal requirement for a nu­trient, and defects in binding affin­ity of an enzyme for a coenzyme resulting in a higher than normal requirement for a vitamin.

Question Biochemical Differences

An important question in nutri­tional science is in the area of bio­chemical differences, either inborn or environmentally induced. Detect­ing such differences and using nu­trition to overcome many of the detr imental effects offers a clear opportunity for improving health.

As demonstrated by the panel­ists, nutrition can irrevocably affect developmental processes.

For example, undernutrition dur­ing early life can permanently re­duce the number of brain cells, whereas overnutrition may lead to increased numbers of fat cells with consequent predisposition to obesity throughout life.

Researchers are far from know­ing all there is to know, and addi­tional nutrients or nutrition-related factors are still being discovered. Additional trace elements are being found to be essential for growth and well-being.

Anticipate Clinical Applications

The clinical applications of these discoveries can be anticipated. An example is the recent discovery of a dihydroxy metabolite of vitamin D which functions as a honnone in the control of calcium and phos­phorus metabolism. It is now being utilized in the treatment of bone diseases.

The Conference found that the status of nutrition research re­mains an urgent and complex sit­uation.

As Senatoi· Henrv Bellmon of Oklahoma observed in his opening address, "Most of us do not have the luxury of waiting for a decade or two before decidin_g what to eat."

And yet, as Dr. Rene Dubos of Rockefeller University stated in his keynote speech, "Biological and so­cial factors inhibit the definition of an ideal diet for the average per­son. . . . Each person has nutri­tional requirements as unique as his fingerprints."

Afraid To Assert Yourself? Call 496-2738

Employee Assistance Program

A Las Vegas, Nev. , television host ( I) interviews Drs. Sarah C. Kaiser and Ceorge Kih:es of NIAMDD's Digestive Disease and Nutrition Program about research advances. The two program directors appeared on the ABC station after being awarded Certificates of Special Recognition from the American Castroenterological Association during Digestive Disease Weck.

Proceedings of Workshop Concerning Blood Plasma Fraction Studies Issued

A new publication, Proceedings of the International Workshop on Technology for Protein Separation and Improvement of Blood Pla,qm.a Fractionation, DH"RW Publication No. (NIH ) 78-1422, is now avail­able.

These published proceedings are a result of a workshop held in Res­ton, Va., Sept. 7-9, 1977.

Workshop Jointly Sponsored

The workshop was jointly spon­sored by the National Heart, Lung, and Blood Institute; Bureau of Bio­logics, FDA; Fogarty International Center; and Bureau of Community Health Services, HSA.

International interest in techno­lo_gical advances in plasma frac­tionation was demonstrated by the attendance of representatives from 19 other countries.

This workshop represents the Division of Blood Diseases and Re­sources initiative to address a na­tional need, mandated by Congress, to support the study of fractiona­tion of blood and clinical investiga­tion of plasma fractions, including research on the use of blood prod­ucts and management of blood re­sources.

Consider 5 Main Topics

Participants in the workshop ad­dressed five main topics: 1) bio­chemical engineerin_g studies, 2) assessment of innovative methods in plasma fractionation, 3) a pro­spective survey of new or improved proteins for potential cl inical use, 4) a survey of new methods of protein separation with potential for large-scale applications, and 5) regulatory, safety, and quality is­sues.

This 561-pal:!e publication is available at $6.75 from the Super-

THE NIH RECORD

Louretta Doherty Ends 18 Years at NIH; Leaves Staff Fond Memories

Louretta Doherty, for many years secretary t o the di1·ector of the Division of Extramural Af­fairs, National Heart, Lung, and Blood Institute, has retired after 18 years at N IH.

She came to the campus in 1960 as a grants a ssistant with the Di­vision of Research Grants Research Grants Review Branch, then worked as a fellowships assistant in its Ca reer Development Review Branch before joining the NHLBI staff in 1963.

Over the years, the consistent excellence of her work has earned Ms. Doherty numerous commenda­tions, including a Superior Per­formance Award.

Those who have known or worked with her will remember most fondly the courtesy, pleasant disposition, and sense of humor that never seemed to desert her, even dul'ing

The box Ms. Doherty is opening con­tains a chime clock--one of the gifts she received at the recent reception in her honor attended by friends and co-workers.

memorable flaps or on dark, rainy :v!onday mornings at \Vestwood.

A native of Joliet, Ill., Ms. Do­herty received her undez·graduate training at DePaul University, Chi­cago, and Northern Illinois Uni­versity. She holds a law degree from DePaul, passed the Illinois Bar examination, and was licensed to practice law in Chicago.

She intends to spend the summer "just loafing around," an indulg­ence she seldom permitted herself at NIH. This fall, presumably well rested and refreshed, she plans to do some traveling. But no 10 coun­tries in 10 days for her: slow and easy would seen. to be her new speed.

intendent of Documents, U.S. Gov­ernment Printing Office, Washing­ton, D.C. 20402, stock number 017-043-00087-1.

Everybody complains of his lack of memory, but nobody of his want of j udgment.-La Rochefoucauld

THE NIH RECORD

Wayne Levillain Retires; Biolab Technician Recalls Years of Change at NIH

After 38 years at NCI, Wayne Levil­lain leaves with fond memories and assurances that he will be missed.

When Wayne Levillain was a boy in Washington, D.C., his family decided he was wasting his time in school; he'd be better off with a job. He hecame one of a crew known as the "bull gang," general helpers in the animal rooms of the old National Cancer Institute labs down on 25th and E Streets.

At the end of June 1978, Mr. Levillain retired as a biolab techni­cian in a descendant of the same lal>-the Division of Cancer Biology and Diagnosis' Laboratory of Mo­lecular Biology. Thirty-eight years had elapsed.

In the course of those years, Mr. Levillain became a surgical techni­cian during his only years away from ~IH, a 4-year stint during World War II with the Army Med­ical Corps at O'Reilly General Hos­pital, Springfield, Mo.

Became Interested in Education

He acquired a new interest in education and took the equivalent of a degree in coUege-level science courses.

He worked under the renowned Dr. Walter Heston, whose DRS mouse classification system is now used across the United States. With Dr. Heston, who retired from NCI in 1975, he assisted in developing prototype equipment used in gel electrophoresis.

The changes that come inevitably with increasing size have been those most notable to Wayne Levil­lain. "T remember when a little building known as Top Cottage stood where the Clinical Center is now. Everyone in Cancer used to get together for dances and par­ties. Work used to get done by call­ing someone on the phone. Now it takes paperwork and a month's t ime."

Not that he became one of the crotchey old-timers, grumbling about the past. "I never met any­one who knew more about how NIH

July 12, 1978

The American Type Culture Collection Develops Resources With NIH Support

( Second of a Two-Part Series)

As noted in the previous issue of the NIH Record (June 27, 1978), "the most diverse collection of reference micro-organisms, viruses, and cell cultures in the world is maintained, authenticated, and perserved at the American Type Culture Collection in Rockville."

New resources arc being devel­oped by the ATCC.

A new Lung Cell Resource Facil­ity is being developed by the A TCC Cell Culture Department with sup­port from the National Heart, Lung, and Blood Institute. An ad­visory committee of experts has been organized by the A TCC to assist in this effort.

The central goals of the program are to develop, char acterize, ex­pand, and distribute populations of lung cells for use in studies of lung biochemistry, function , develop­ment, and/or pathophysiology.

Emphasis is on cell Jines der ived from normal and abnormal (but n ot cancerous) lung tissues of the human and various laboratory ani­mals.

This is part of an over-all ATCC research program on the develop­ment and study of functional types of cultured cells.

Test Cells for NfH

Remaining supplies (low-pas­sage) of the human diploid lung cell line, WI-38, have also been de­posited with the A TCC. The cells have been characterized, expanded, and tested for NIH under contract with the Division of Research Re­tources.

Special low-passa~e lots are available for vaccine purposes through an NIH Use Committee. Characterized lots at slightly higher passage levels are available for research purposes.

Other human diploid lines avail­able for general distribution are MRC-5 and IMR-90.

works," remarked Dr. Michael GotLesman, of the LMB. "And he knows because he's on good, cor­dial working terms with everyone here. His flexibility when the lab changed emphasis from animal ge­netics to molecular structure was most impressive. We'll miss him."

A sentiment echoed without res­ervation by his chief, Dr. Ira Pas­tan, and others. "He's reliable and conscientious and he will definitely be missed," Dr. Pastan noted.

Mr. Levillain has the future pretty clearly mapped out. "My wife Virginia and I plan to do a lot of traveling. I've read about the Florida Keys and the Grand Canyon, and now we hope to see them." And, he adds, he plans to do a lot of fishing, the kind of fishing that has won h im trophies in the past. "You can't leave that out."

The ATCC also characterizes, stores, and distributes additional diploid lines from the human, mon­key, and rabbit for the Bureau of Biologics, F ood and Drug Adminis­tration.

The Cell Culture Department is also engaged in the development of new systems for the culture of pan­creatic epithelium for the National Cancer Institute, and recently the A TCC was awarded a contract by NCI for the development a nd char­acterization of differentiated cells from various leukemias, bone mar­row, and other tissues.

Conducts Virological Assays

Virological assays on some of the derived cells will be carried out in collaboration with the Virology De­partment.

The ATCC has established a Cell Source Information Bank to pro­vide information to investigators about potential sources for special­ized types of cultured cell strains and lines. The role of the CSIB is solely that of a clearing house and referral service.

Information on the sources and unique characteristics of special­ized cells is currently available only upon direct inquiry but may be de­veloped into published fo1·m at a later date.

The ATCC Virology Department is incorporating into its collection the viral reagents formedy distrib­uted by the Research Resources Branch of the National Institute

This electron micrograph typifies some of the functional types of cells sought in lung tissue culture lines for the new Lung Cell Resource Facility at the ATCC. The photograph shows macro­phages ( M ) , type I pneumocytes ( I ) , type 2 pneumocytes ( 11 ) , fibroblasts (Fl, and seve ral additional cell types.

Page 9

Dr. Alan A. Schreier Is New Grants Associate

Dr. Alan A. Schreier has joined the NIH Grants Associates Pro­gram for a year of training in health science administration.

The Grants Associates Program prepares biomedi­cal and behavioral scientists for roles as health science administrators.

Dr. Schreier graduated from the University of Chi­cago in 1967, re­ceiving a B.S. de-

Dr. Schreier gree in physics. He then went to the

Massachusetts Institute of Tech­nology where he earned a Ph.D. degree in biophysics in 1973 with a thesis on nucleic enzymology and structure.

Before coming to NIH, he was a postdoctoral fellow at Stanford University Medical School's depart­ment of biochemistry where he studied protein structure and mo­tility from 1973 to 1977.

He has also worked in an indus­trial R & D environment, with the Nicolet Technology Corporation of Mountain View, Calif., where he participated in the development of new NMR spectrometer systems, 1977-78.

He is the recipient of an NIH Predoctoral Fellowship, an Ameri­can Cancer Society Postdoctoral Fellowship, and an NIH Postdoc­toral Fellowship.

of Allergy and Infectious Diseases. Initially, this will include 4 major

groups of viruses (68 enteroviruses, 31 adenoviruses, 90 rhinoviruses, and 70 arboviruses) plus their re­spective homologous antisera. As the reagents are being accessioned the A TCC is performing assays for potency.

The A TCC will store, catalogue, and distribute the reagents and, when necessary, will replenish de­pleted stocks or stocks with low via­bility. This is being carried out with contract support from NIAID.

A program to establish a com­plete reference collection of DNA and RNA oncogenic viruses is also being carried out by the Virology Department with contract support from NCI.

Representative lots of the onco­genic viruses supplied to research­ers by the Office of Program Re­sou1·ces and Logistics of the Viral Oncology Program are being thor­oughly characterized by the ATCC and are being preserved as refer­ence reagents for eventual distribu­tion.

Further information about the A TCC resources can be secured from Dr. Richard Donovick, Dir ec­tor, 12301 Parklawn Drive, Rock­ville, Md. 20852, telephone (301) 881-2600.

Page 10 July 12, 1978

K3YGG Provides Aid in Real, Simulated Emergencies; 'In Vitro Carcinogenesis' Makes 805 Radio Contacts During 24-Hour Exercise And 4 Technical Reports

During a 24-hour period beginning at 2 p.m. on June 24, the NIH Radio Amateur Club demonstrated its ability to provide emergency communica­t ions by participating in the annual American Radio Relay League field day.

From a location in the Multi Level Parking garage, and pow­ered by a portable gasoline genera­tor furnished by the Grounds Main­tenance and Landscaping Branch, DES, 13 club members operating in shifts were able to make 805 in­dividual contacts-a rate of more than one every 2 minutes.

The 2, 10, 15, 20, and 80 meter FCC-authorized amateur radio fre­quencies were used, and both CW (code) and phone (voice) modes were employed.

Also Monitor CB

As a further demonstration of capabilities in an emergency situa­tion, area police, fire, and CR chan­nels were monitored.

Contacts were recorded from 45 of the 48 continental United States, five Canadian provinces including Newfoundland, several ships at sea, and one contact each in the South Pacific, Mexico, and Great Britain.

Began in 1963

In the 15 years since the incep­tion of NIHRAC, the club has dealt with real, not ju5t simulated emer­gencies.

In fact, just after NIHRAC began operating K3YGG in 1963-with partia l support from the P lant Safety Branch and from the NIH West Africa Research Unit-Dr. Victor Zeve in Ghana sought help in obtaining medical supplies a nd equipment.

Emergency in Africa

Through NIHRAC, Dr. Zeve, with h is own 2-way radio equip­ment to offset the lack of tele­phones, contacted colleagues at NCI concerning medicines needed to aid his sort, suffering from an asth­matic condition.

Later, a schedule of twice-weekly contacts was set up, greatly reduc­ing the time lag in obtaining essen­tial supplies and equipment for the researchers then in Africa.

Since that time cardiograms have been transmitted, numerous re­quests for special medicines and treatment have been received and refcne<l to appropriate sources.

OSCARS Boost Range

Eight OSCARS (Orbital Satel­lites Carrying Amateur Radio) have been launched by NASA, and two remain active, greatly extend­ing the range of broadcast and re­ception.

About half of the visitors to the field day operations were CB'ers, contacted on their own frequencies, who expressed interest and stopped by. Beginner's license exams can

Dr. William Hook inspects the porta­ble antenna located atop the Multi Level Parking garage.

With an aerial lift, better known as a cherry-picker , loaned by the Shops Branch, Division of Engineering Serv­ices, extra support was provided for high frequency wire antennas and a VHF antenna.

Taking the first shift at the start of the 24-hour field day are NIHRAC members (I to r) Leonard Aberbach, Pat Silva, Dr. Robert Silva, and Dr. Victor Zeve.

be g iven by mail. Visitors are welcome at the club's

regular meetings in Bldg. 10, Room B2-N104, at noon each Thursday. Call Leonard Aberbach, 496-4131, for further information.

Now Available at NCI Availability of a report, In Vitro

Carcinogenesis, was recently an­nounced by the National Cancer Institute.

The report provides a gu ide to the literature, recent advances, and procedures for short term studies of carcinogenesis ( cancer causa­tion) in laboratory systems.

The publication is based on pre­sentations made at the seminar and workshop held at t he Given Insti­tute of Pathobiology, University of Colorado in Aspen, July 18-23, 1976.

In Vitro Carcinogenesis is one of the series of Technical Reports published by the Institute's Car­cinogenesis Testing Program. Cop­ies are available from the Office of Cancer Communications, NCI, Be­thesda, Md. 20014.

The program has also recently published reports on animal tests of four ~ompounds for carcinogen­icity.

Used in Dyes, Explosives

An ingredient in explosives and an intermediate in dye manufac­ture, 2,4-dinitrot oluene, was given in feed to mice and rats for 78 weeks.

According to the report from NCI, 2,4-dinit rotoluene caused be­n ign tumors in male and female rats. The benign tumors were not considered a sufficient basis for establishing carcinogenicity, how­ever.

The test produced no evidence of carcinogenicity of the compound in mice.

A naturally occurring nitro chemical found in plants, nuts, and fungi, 3-nitropropionic acid, was given by stomach tube to rats and mice for periods between 104 and ll0 weeks.

The NCI report indicated that 3-nitropropionic acid was not car ­cinogenic in female rats or in male or female mice under the test con­ditions.

In male rats there was an in­creased occurrence of liver and pancreas tumors, primarily benign, but no conclusive evidence that the chemical was carcinogenic.

Another compound, 1-nitronaph­thalene is a chemical intermediate in dye manufacture, and has a variety of other commercial uses. This compound was given in feed to rats and mice for 78 weeks.

NCI reported that 1-nitronaph­thalene was not found carcinogenic under the test conditions.

Chloropicl"in, developed as tear gas and cunently used as a n agri­cultural fumigant in stored grain and soil, was given orally by stom­ach tube to rats and mice for 78 weeks.

THE NIH RECORD

Symbols in, HEW' s Seal

THE HEW SEAL

Most NIH'ers have seen t he HEW seal many t imes, on station­ery, publications, and other mate­rials. But have you ever looked closely at the HEW seal? Do you know what the symbols mean?

The bald eagle stands for the United States. The staff of Aescu­lapius, at the center, is the accepted symbol for medicine or health. Aesculapius is the god of medicine in classical mythology. T he snake is the symbol of renewal and re­generation, probably because it sheds its skin.

The open book symbolizes educa­tion; the surrounding chain repre­sents strength or coordinated wel­fare.

The Latin motto inscribed on the scroll, Spes Anchora Vitae, means "hope is the anchor of life."

Designed by Sculptor

The designer of the seal was Thomas Hudson Jones, the sculptor who created the Tomb of the Un­known Soldier in 1931. He worked for the Army's Institute of Her­aldry at Cameron Station, Va., from 1944 until 1962 and designed sculpture and medals for many agencies and officials. He died in 1969 at the age of 77.

He created the World War II Victory Medal, to which all veter­ans of the conflict are entitled, and the medal for the President's A ward for Distinguished Federal Civilian Service.

The first HEW Secretary, Ovet a Culp Hobby, submitted the design of the official seal soon after the Department was established in April 1953, and President Dwight D. Eisenhower approved the design Dec. 17, 1953.

According to an NCI report sum­mary, the bioassay of chloropicrin did not give con clusive evidence for carcinogenicity in mice. In :rats, the test was inadequate because of short survival time of dosed ani­mals.

Copies of these four bioassay r e­ports on tests by the Institute's Carcinogenesis Testing Program may also be obtained from the Of­fice of Cancer Communications, NCI, Bethesda, Md. 20014.

THE NIH RECORD

DR. BLACK (Continued from Page 1)

with the Montgomel'y County Health Department and as Beau­voir Elem en tal'y School physician.

From 1963 she was a medical officer with the D.C. Department of Public Health. She also organized and operated a sick children's clinic at the Southwest Heal th Center in Washington, D.C.

Dr. Black has been a clinical instructor in pediatrics at G.W.U. since 1950, and in June 1975 re­ceived a general alumni association award for 25 years of meritorious service as a member of its faculty.

Since 1966, she has been on the senior advisory staff of D.C. Chil ­dren's Hospital as well as consult­ant in pediatrics at Suburban Hos­pital.

Helen Riches Retires From NIDR; Served As Planning Officer

Helen M. Riches recently retired from the National Institute of Den­tal l{esearch.

She began her Government ca­reer in 1944 as a cryptanalyst, and worked for several year~ in the De­partment of the Air Force and the Central Intelligence Agency.

Mrs. Riches joined the staff of the Office of Program Planning, NIH, in 1963. In 1964 she trans­fened to NIDR, and in November 1973 became the Institute's plan­nin~ officer, a position sh<:? held at the time of her retirement .

Mrs. Riches plans to work as a consultant and to pursue her inter­ests in the arts and human ities.

NIH Visiting Scientists Program Participants 6/12-Dr. Liang-Hsien Eli Hahn,

Taiwan, Laboratory of Molecular Biology. Sponsor: Dr. Kenneth Ya­mada, NCI, Bg. 37. Rm. 4E16.

6/12-Dr. John L. Plummer, Australia, Laboratory of Pharma­cology. Sponsor: Dr. J. R. Bend, NIEHS, Research Triangle Park, N.C.

6/ 18-Dr. Sarah Ben-Or, Israel, Endocrinology and Reproduction Research Branch. Sponsor: Dr. Kevin Catt, NICHD, Bg. 10, Rm. 12N212.

6/ 18-Dr. Jagdish Gulati, United States, Laboratory of Physical Bi­ology. Sponsor : Dr. Richard Po­dolsky, NIAMDD, Bg. 6, Rm. 110.

6/ 26- Dr. Menashe Ben-David, Israel, Endocrinology and Repro­duction Research Branch. Sponsor: Dr. Andreas Chrambach, NICHD, Bg. 10, Rm. 121'212.

6/ 26-Dr. Takahisa Shindo, Ja­pan, Laboratory of Kidney and Electrolyte Metabolism. Sponsor: Dr. Kenneth Spring, NHLBI, Bg. 10, Rm. 6N310.

July 12, 1978

Heart Disease Experts Evaluate and Update 1971 Task Force Report

Dr. Fishman 11) and Dr. Levy look over the recommendations made by the recent working group of expert cardiologists on the 1971 Task Force Report.

A working group of cardiovascu­lar disease experts, convened to evaluate and update the Report of the 1971 Task Force on Arterio­sclerosis, recently submitted their findings and recommendations to Dr. Robert I. Levy, Director of the National Heart, Lung, and Blood I nstitute.

Reexamine 1971 Report

Chaired by Dr. Alfred P. Fish­man, University of Pennsylvania School of Medicine, the group de­termined the extent to which rec­ommendations of the 1971 Task Force had been implemented and to evaluate their impact on re­search and clinical progress toward prevention and control of arterio­sclerosi~ and its complications.

The group was asked to decide whether the 1971 i:eport was still timely as a basis for future pro­gram planning by NHLBI or should a second task force similar to the first be established to extend or redefine earlier goals and prior­ities.

The working group noted that the 1971 Task Force had done its job exceptionally well. It had de­veloped sound research strategies for combating a disease nearly ubiquitous among American adults and whose complications, such as heart attacks, sudden cardiac death, and strokes, account for some 85 percent of aJl disability and death from cardiovascular dis­orders.

Many Task Force recommenda­tions had been put into effect by the Institute, including:

• Initiation of clinical trials to

6/26--Dr. Takashi Uchiyama, Japan, Metabolism B,·anch. Spon­so1·: Dr. Thomas A. Waldmann, NCT, Bg. 10, Rm. 4N117.

6/ 26-Dr. Shigekazu Uga, Ja­pan, Laboratory of Vision Re­search. Sponsor: Dr. Toichiro Ku­wahara, NEI, Bg. 6, Rm. 227.

July 26 Is Seminar Nomination Deadline

July 26 is the deadline for B/I/ D Directors' nominations for the 1978-79 Grants Associates Seminar Series.

These weekly seminars, begin­ning Sept. 18, will cover a wide variety of topics related to extra­mural programs.

Those intP.rested should forwa1·rl their c.v.'s through their immediate supervisors to their respective B/ I/D Directors.

Directors are asked to select for nomination no more than two nom­inees by forwarding those c.v.'s with a memo of endorsement to A. Robert Polcari, Executive Secre­tary, Grants Associates Program, Westwood Bldg., Room 2A-03.

Or. William Raub, Acting Asso­ciate Director for NTH Extramural Research and Training, wiJI make the final selection.

ascertain whether modification of certain factors known to increase risk from premature arteriosclero­sis could reduce morbidity and mor­tality.

• Initiation of clinical trials as­sessing the relative roles of medical and ~urgical treatment in patients with angina pectoris or other clini­cal manifestations of coronary heart disease.

• Intensification of research seek­ing- safe, sensitive, non-invasive methods for detecting arteriosclero­sis.

• Expansion of research on l!'e­netic factors in arteriosclerosis or predisposing conditions.

• Increased research emphasis on mechanisms of blood-vessel in­jury an<l repair.

• Development of animal models of arteriosclerosis.

• E stablishment of special re­~earch and clinical facilities to at­tack specific ·problems posed by pre­cursors of arteriosclerosis.

• Expansion of research con­cerned with health education and attitudes.

These efforts have produced nu­merous research and clinical ad­vances. They have also opened up a variety of promising new avenues for exploration and numerous re­search opportunities that should be explored.

Need To Redefine Priorities

The working group concluded that the time was ripe for a second task force to help redefine goals and priori tics.

The report, entitled A rferiosc/er­osis: The Report of the 1977 Work­ing Group to Review the 1971 Re­port b11 the NH f.,J Task F'orce on Arteriosclerosis ( DREW Publica­tion No. (NIH) 78-1/\26), is avail­able on request from the Public Inquiries and Reports Branch, NHLBI, Bldir. 31, Rm. 5A-03, tele­phone 496-4236.

Page 11

Menopause: Topic of TV Simulcast From NIH, S.C. For Public, Professionals

Menopause: An Update was the subject of a live medical presenta­tion via satellite yesterday, July 11, from 5 :30 to 8 p.m., as part of the REACH program (Research, Education, and Community Healt h ).

REACH brings togethet· scien­tists from NIH and the Medical University of South Carolina to discuss the latest findings in medi­cal research and their implications for a variety of health problems. Monthly programs are planned.

The live telecast, along with vid­eotaped segments, enabled two-way interaction between panelists at NlH and at MUSC.

Viewers were also able to ask questions of panelists via toll-free telephone.

Host-moderators of the program were Dr. Griff T. Ross of NIH and Dr. Estelle R. Ramey, professor of physiolog-y and biophysics, George­town University.

Senator Strom Thurmond of South Carolina p1·esented a taped welcome to the audience.

The first portion of the program, Menopause: What It I s, was seen by the public in South Carolina and southeastern states served by the Southern Educational Commu­nications Association. Panelists in­cluded Dr. J. Richard Sosnowski at MUSC, and Drs. Mortime1· B. Lipsett and Stanley Korenman at NIH.

The second portion of the pro­gram, for medical audiences, was shown over closed circuit, at 38 member institutions of the Health Communications Network, Division of Continuing Education, Medical U niversity of South Ca1·olina; at the Lister Hill Center, National Library of Medicine, Bethesda, Md.

Also, at The Greater Cleveland Hospital Association and t he Ohio Valley Medical Microwave System ( 76 hospitals with 23 receiver sites) ; and other facilities in the 1-1 states served by the Southern Educational Communications Asso­ciation.

Presentations during the second portion of the prog-ram included:

From NIH: Hormonal Features of the Peri-Menopausal and Meno­pausal Period (Dr. Stanley G. Kor­enman) ; and Indications and Risks of E strogen in the Menopause (Dr. Mortimer B. T,ipsett) .

From MUSC: Some Psychologic and Metabolic Aspects of the Cli­maclerium (Dr. H. Olive r Will iam­son); and Endomctrial Carcinoma (Dr. Paul B. Underwood, Jr.).

For further information on the scdes of prog-rams, contact the Di­vision of Continuing Education, Medical University of South Caro­lina, 171 Ashley Ave., Charleston, s.c. 29403 (803-792-4431).

Page 12

Dr. Frederic C. Bartter Receives the Koch Award From Endocrine Society

Dr. Frederic C. Bartter, chief of the Nat ional Heart, Lung, and Blood Jnstitute's Hypertension­Endocrine Branch, has been named 1978 recipient of the Fred Conrad Koch Award, the highest honor be­stowed by The Endocrine Society.

Dr. Bartter was cited for orig­inal research in clinical and exper­imental endocrinology performed

, over the past 35 years. He is internationally known for

his contributions on the role of the renin-angiotensin-aldosterone sys­tem in the regulation of blood pressure; the part played by adre­nocortical and pituitary hormones in the maintenance of fluid and electrolyte balance; and the roles

Dr. Bartter's extracurricular inte rest in mushrooms, upon which he became an expert, led to his participation in clinical studies of thioctic acid as an antidote for accidental poisoning by a common, potentially deadly species: Amanita phallo ides, also known as "the death c up."

of parathyroid hormone, thyrocal­citonin, and other factors in cal­cium, phosphorus, and bone metab­olism.

Born in Manila, the Philippines, Dr. Bartter earned his B.A. and M.D. degrees at Harvard. He joined the Public Health Service in 1942 as Director of Laboratories for the USPHS Hospital at Sheepshead Bay, N.Y.

He served with the Pim Ameri­can Sanitary Bureau, then joined the staff of the NIH Laboratory of Tropical Diseases in 1945.

He has headed the NHLBI H}•­pertension-Endocrine Branch since 1951, and served as the Institute's clinical director from 1971 to 1976.

During his 36 years with PHS, Dr. Bartter has conducted basic and clinical research in a variety of fields, including biochemistry, tropical medicine, pediatrics, and medicine as well as endocrinology.

In 1962, Dr. Bartter, with Dr. Pacita Pronove and other col­leagues, defined a disorder charac­terized by hyperplasia of renin­secreting cells of the kidney, exces-

J uly 12, 1978

PHS 180th Anniversary Ceremony Features Talks By Califano, Richmond

To celebrate the 180th anniver­sary of t he Public Health Service­founded July 16, 1798-a formal ceremony will be held on Wednes­day, July 26, from 3 to 4:30 p.m., at the Clinical Center Masur Audi­torium, featuring talks by HE°W Secretary Joseph A. Califano, Jr., and PHS Surgeon General Dr. Julius B. Richmond.

All employees are invited to hear Secretary Califano discuss Future Directions of PHS, and Dr. Rich­mond speak about Highlights of the 180 Years.

Following the ceremony, a recep­tion will be held from 5 to 7 p.m. at the Naval Officers' Club, Na­tional Naval Medical Center.

All are invited to both events, but a reservation and $5 fee are re­qui red for the reception. The fee and r eservation must be in by July 13. For further information, con­tact the Administrative Services Center/ OM, 443-2516, in Room 5-77, Parklawn Bldg.

Complex Carbohydrates: July Conf. Considers Role in Bio Recognition

The Role of Complex Carbohy­drates in Biological Recognition will be the topic of a conferenr.e July 17-19 in Wilson Hall, Bldg. 1, beginning at 8 :30 a.m.

Thirty speakers from six coun­tries will gather for the 3-day ses­sion to review recent advances in the knowledge of complex carbohy­drales and their role in such phe­nomena as hormone actions, toxic­ity reactions, the immune response, and cellular adhesion.

The conference was organized by Fogarty Scholar-in-Residence Dr. Nathan Sharon and Dr. Victor Ginsburg of NIAMDD. Dr. Sharon comes from the Weizmann Institute of Science in Rehovoth, hrael, where he has headed the biophysics department since 1973.

The conference is being spon­sored by the National Cancer Insti­tute, the National Institute of Allergy and Infectious Diseases, the National Institute of Al·thritis, Metabol ism, and Digestive Dis­eases, the National Institute of Dental Research, and the Fogarty Jnternational Center.

Pre-registration is preferred, and can be made by calling the FIG at 301-496-2516.

sive aldosterone production, and potassium depletion. Now known as Bartter's syndrome, the condition proved to be relatively common once Dr. Bartter's group devised re, liable methods for its detection.

Two Recent Explosions Are Reminder of Need For Safety Practices

Because explosions in two NIH laboratories recently occurred as a result of unsafe handling of chemi­cals, a thorough review of safety practices by everyone handling chemicals has been suggested.

This recommendation was made by Dr. Rudolf G. Wanner, associate director for Environmental Health and Safety, Division of Research Services.

At the scene of the fh·st explo­sion, the NIH Fire Department re­sponded to a 2 a.m. call on smoke odor and located the source as a Clinical Center laboratory.

Entrance to the laboratory was delayed. The door lock had been changed and did not yiC>ld to the NIH master key system.

When entrance was finally gained through an escape hatch and a neighboring lab, firemen found a smoldering stack of papel· directly over an exploded refrigerator.

Some of the contents were thrown out; but fortunately, con­tainers with radioactive material and flammable liquid remained un­damaged.

Also, exterior windows were broken, and several bottles in an adjoining laboratory were shat­tered.

The cause of the explosion was a beaker with isopentane residue, stored in the refrigerator 6 hours earlier. An explosive vapor mixture developed inside and detonated, ig­nited by an electrical spark from the thermostat.

The other explosion occurred dur­ing working hours at a National Institute of Environmental Health Sciences laboratory. It involved several test tubes containing per­chlo1·ic acid and an employee suf­fered face injuries.

The fume hood was not suitabie for work with perchloric acid. The test tubes were placed near the front edge of the hood without a safety shield.

Safety Glasses Essential

Safety glasses were not worn by the injured employee. Other chemi­cals were stored in the hood, and one bottle with picric acid was broken.

Since this explosion, Christopher Hunt, NIEHS safety officer, has initiated a system to ensu re safer handling of perchloric acid: the chemical has been placed on a con­trol list and protocol requires pe1·­mission for its use.

Only explosion-proof refrigera­tors are safe for storage of flam­mables and explosives. Employees handling chemicals should always use safety glasses, shields, and hoods designed for work with toxic, corrosive, and explodable chemi-

TIIE NIii RECORD

Dr. Clarence J. Gibbs has been elected to membership in the Washington ( D.C. ) Academy of Medicine. It is the latest honor for the noted micro­biologist who, within the past year, has received the Distinguished Alumni Award in Medical Arts from Catholic University and an honorary doctorate in medicine from the Faculte de Medi­cine, University of Marse ille, France. Dr. Gibbs, recipient of the DHEW Distinguished Service Awarcf, is deputy chief of the NINCOS l aboratory of Central Nervous System Studies.

Conferees Consider Role Of Saliva in Prevention Of Dental Caries

The National Caries Program, National Institute of Dental Re­search, sponsored an international conference on the role of saliva in the prevention of dental caries in June at the State University of New York a t Stony Brook.

The conference was unusual in that it pointed out a new direction in dental research- a shift toward dealing with the oral cavity as an ecosystem in which oral bacteria and host factors interact rather than focusing on specific organisms as potentia l agents of oral disease.

Key points evolving from the con­ference were the recognition that a large amount of exact information about structure and composition of saliva now exists; and that new sophisticated tools and techniques for separating and identifying sali­vary factors are now available, making it possible to begin to look at the functions of specific salivary components.

Also, two clearly identified com­pounds in saliva, affecting calculus formation and caries, have now been identified- statherin and sia­lin.

The proceedings of this confer­ence will be published soon.

cals, according to Dr. Wanner. The Environmental Safety

Branch, DRS, will provide con sul­tation on the safe handling, stor­age, and disposal of all chemicals, and is available for assist ance in problem areas.

Dr. Bartter is author or co­author of more than 300 publica­tions and has received numerous honors and awards, including the Meritorious Service Medal of NIH. * U.S. GOVERNMENT PR INTING OFFICE, 1978 260·901/ 21