k7_1.Nervous System(Pa)

7/23/2019 k7_1.Nervous System(Pa)

1/43

NERVOUS SYSTEMNERVOUS SYSTEM

. CENTRAL :. CENTRAL :

- COMPLEX- COMPLEX

- CONTROLE- CONTROLEORGANORGAN

INDIVIDUALINDIVIDUAL

. PERIFER.. PERIFER.


2/43

NERVOUS SYSTEMNERVOUS SYSTEM

COMPONENT:COMPONENT:

NEURONNEURON

GLIAGLIA

MICROGLIAMICROGLIA

CON.TISSUECON.TISSUE

BLOOD VESSELBLOOD VESSEL


3/43

NEURONNEURON

BODY (PERICARION)BODY (PERICARION)

- NEUROfILAMIN- NEUROfILAMIN

- MICROTUBULUS- MICROTUBULUS- LISOSOM- LISOSOM

- MITROCHONDRIA- MITROCHONDRIA

- RET.ENDOPASMIC- RET.ENDOPASMIC

- NUCLEUS/NUCLEOLUS- NUCLEUS/NUCLEOLUS


4/43

NEURONNEURON

AXON & DENDRITAXON & DENDRIT

PROSESSUS OF NEURONPROSESSUS OF NEURON

ELECTRIC IMPULSELECTRIC IMPULS PERICARIONPERICARION


5/43

GLIA CELLGLIA CELL

- ASTROCYTEASTROCYTE

- OLIGIDENDRITOLIGIDENDRIT

-

EPENDEMALEPENDEMAL- PLEXUS CHOROIDALISPLEXUS CHOROIDALIS


6/43

MICROGLIA CELLMICROGLIA CELL

LIKE MACPHAGE AND MONCYTELIKE MACPHAGE AND MONCYTE

PHAGOCYTE.PHAGOCYTE.

CON.TISSUECON.TISSUE::- MENINGEN- MENINGEN

- PHERIACULAR FBLAST- PHERIACULAR FBLAST

BLOOD ESSELBLOOD ESSEL! OTHER! OTHER


7/43

REAC.N.CELLREAC.N.CELL TRAUMATRAUMA

NEURON : AXON DEMAGENEURON : AXON DEMAGE KROMAKROMA

TOLISISTOLISIS REGENERATION (-)REGENERATION (-)

ASTROCYTE : - HIPERPLASI & HIPERASTROCYTE : - HIPERPLASI & HIPER TROPHYTROPHY GLIOSISGLIOSIS FIBROTICFIBROTIC

MICROGLIA :MICROGLIA :

PHAGOCYTEPHAGOCYTE OLIGODENDRIT & EPENDIMALOLIGODENDRIT & EPENDIMAL

MINIMAL REACTIONMINIMAL REACTION DEMAGEDEMAGE


8/43

INTRA CRANIAL LESIONINTRA CRANIAL LESION

OEDEMA:OEDEMA:

DIFFUSA - HICAPNIA" HIPOXIADIFFUSA - HICAPNIA" HIPOXIA

ASC.ASODILTION.ASC.ASODILTION. - ASOGENIC- ASOGENIC AS.PERMAS.PERM

- CYTOTOXIS- CYTOTOXIS AS.DAGE.AS.DAGE.

- ENTR.DAGE- ENTR.DAGE INTERALINTERAL LOCAL - INF"TRMA"NEOPL"AS.DGLOCAL - INF"TRMA"NEOPL"AS.DG


9/43

IN.CR.LESSIONIN.CR.LESSION

P.IN.CR.## - OL.##P.IN.CR.## - OL.## SPEACE $SPEACE $

% COMPENSATION : CSF $" B.OL.$% COMPENSATION : CSF $" B.OL.$ BRAIN ATROPHY.BRAIN ATROPHY.

% DECOMTION% DECOMTION : CRISIS.: CRISIS. PAPILPAPIL

OEDEMA" OMITUS" PAIN (HEAD)"OEDEMA" OMITUS" PAIN (HEAD)"

SENSORIUM $SENSORIUM $ COMACOMA


10/43

IN.CR.LESSIONIN.CR.LESSION

EPILEPSI : - LOCAL (SENSORIC)EPILEPSI : - LOCAL (SENSORIC)

- GENAL (NEOPL"ABSCES)- GENAL (NEOPL"ABSCES)

HIDOCEPHALUS : FOSA POST.HIDOCEPHALUS : FOSA POST. ENTR.I AND AUA DUCT (DAGE)ENTR.I AND AUA DUCT (DAGE)

SITEMIC : HIPTSI" BRADI CARDIA"SITEMIC : HIPTSI" BRADI CARDIA"

PULMONAL OEDEMA" ULC.GIT/TUPULMONAL OEDEMA" ULC.GIT/TU (BLOODY)" ACUTE PANCRTIS.(BLOODY)" ACUTE PANCRTIS.


11/43

CEREBRAL DEMAGECEREBRAL DEMAGE

GUN SHOT: - COMPRESION -- CONTUGUN SHOT: - COMPRESION -- CONTU

SIOSIO FRATURE.FRATURE. - PENETRATION -- INTRA- PENETRATION -- INTRA

CRANIAL (LOCAL)CRANIAL (LOCAL) INFECTION.INFECTION.

- PERFORATING ' HIGH- PERFORATING ' HIGH

RISKRISK DEAD/INF & EPILEPSIDEAD/INF & EPILEPSI


12/43

CEREBRAL DEMAGECEREBRAL DEMAGE

NON GUN SHOT.NON GUN SHOT.

% PRIMER LOCAL% PRIMER LOCAL CONTUSIO"CONTUSIO"

TRAUMA CRAN. NERE" PITTARY"TRAUMA CRAN. NERE" PITTARY"

BRAIN STEAM.BRAIN STEAM.

DIFFUSA DIFFUSA PROS.NEURONPROS.NEURON

DEMAGEDEMAGE SMALL BLID.IN THESMALL BLID.IN THEC.COLSUM AND BRAIN STEEMC.COLSUM AND BRAIN STEEM

DISTAL AXON DEG.(DIFFUSA)DISTAL AXON DEG.(DIFFUSA)


13/43

CERABRAL DEMAGECERABRAL DEMAGE

% SCUNDER (TRAUMA COMPTION)% SCUNDER (TRAUMA COMPTION)

INTRA CR.BLD" TR.EX.CR.ART" I.INTRA CR.BLD" TR.EX.CR.ART" I.

CR.HERNIASI" HIPOXIA (HIPOTENCR.HERNIASI" HIPOXIA (HIPOTEN SION" INCR.INTR.CR.TENTION" FATSION" INCR.INTR.CR.TENTION" FAT

EMBOLISM" TRAUMATIC NECK BL.EMBOLISM" TRAUMATIC NECK BL.

ESSEL AND RESPIRATORY OBSTR.ESSEL AND RESPIRATORY OBSTR.


14/43


15/43

TR.SPINALIS TRAUMATIC.TR.SPINALIS TRAUMATIC.

PARA/TETRAPLEGIAPARA/TETRAPLEGIA

* + (TR.ACCIDENT)" MAN $* YRS* + (TR.ACCIDENT)" MAN $* YRS

TYPE : OPEN AND CLOSED.TYPE : OPEN AND CLOSED.

COMPL.:COMPL.: DEG.ANT.RETR." POSTDEG.ANT.RETR." POST

TR.SIRINGOMYELIA" PARAPLEGIATR.SIRINGOMYELIA" PARAPLEGIA

T.U.INF." CHES PAIN" MUSCLET.U.INF." CHES PAIN" MUSCLEEAKNESS.EAKNESS.


16/43

COMPR.M.SP AND BRANCHCOMPR.M.SP AND BRANCH

ETIOL : - PROLAPS DISC.INT.ERTB.ETIOL : - PROLAPS DISC.INT.ERTB.

- NEOPLASM- NEOPLASM

- SKLETAL DISTR.- SKLETAL DISTR.- INFECTION- INFECTION

- ASC.DISEASE- ASC.DISEASE

- TRAUMATIC.- TRAUMATIC.


17/43

HYDOCEPHALUS.HYDOCEPHALUS.

INTRA CR. C.S.F. INCREAST.INTRA CR. C.S.F. INCREAST.

TYPE : - PRIMERTYPE : - PRIMERCSF OBSTRUCT" ABCSF OBSTRUCT" AB

SORBT.DISTURB.(ARACHNOSORBT.DISTURB.(ARACHNOID ILLI)" PROD.CSF INCR.ID ILLI)" PROD.CSF INCR.

- SCUNDER- SCUNDER COMPSATOIRCOMPSATOIR

( INFARK" ATROPHY )( INFARK" ATROPHY )


18/43

SIRINGOMYELIASIRINGOMYELIA

ETIOL : - DISTR.MEDULLA GROTH.ETIOL : - DISTR.MEDULLA GROTH.

- DISTR.CSF.CIRCULATION- DISTR.CSF.CIRCULATION

- TISSUE DESTR. (TRAUMA M.- TISSUE DESTR. (TRAUMA M. SPINALIS" NEOPLAM)SPINALIS" NEOPLAM)

CLINIC:- MUSCLE EAKNESSCLINIC:- MUSCLE EAKNESS

- LIMBUS ATROPHY- LIMBUS ATROPHY

- ANASTESIA.- ANASTESIA.


19/43

CEREBRO VASC.DISEASECEREBRO VASC.DISEASE

STROKESTROKE

CEREBRAL INFARKCEREBRAL INFARK

I.CRANIAL BLD.I.CRANIAL BLD. SYSTEMIC HYPERTENTION & CNSSYSTEMIC HYPERTENTION & CNS

M.SP.INFARKM.SP.INFARK

NEONATUS I.CRANIAL BLD.NEONATUS I.CRANIAL BLD. CEREBRO ASCULAR MALFORM.CEREBRO ASCULAR MALFORM.


20/43

CNS INFECTION.CNS INFECTION.

BACTERIABACTERIA LEPTO" PACHYMYTISLEPTO" PACHYMYTIS

CEREBRAL ABSCESCEREBRAL ABSCES

TUBERCULOSETUBERCULOSE SYPHYLISSYPHYLIS

IRALIRAL

YEASTYEAST PARASITPARASIT


21/43

DEMYELINATINGDEMYELINATING

TYPE : - PRIMERTYPE : - PRIMER

- SCUNDER- SCUNDER

MULTIPLE SCLEROSISMULTIPLE SCLEROSIS

####PATH : - LIPID MYELIN DISTR.PATH : - LIPID MYELIN DISTR.

- AUTOIMUN DISTR.- AUTOIMUN DISTR.

- POISON- POISON CNSCNS

- CNS IRAL INFECTION- CNS IRAL INFECTION


22/43

DEMYELINATINGDEMYELINATING

CLINIC : - * ' * YRSCLINIC : - * ' * YRS

- PARESTESIA (*+)- PARESTESIA (*+)

- OPTIC NEURITIS (*+)- OPTIC NEURITIS (*+) - DIPLOPIA (,*+)- DIPLOPIA (,*+)

- DISTR.OF .URRIA FS (0+)- DISTR.OF .URRIA FS (0+)

- ERTIGO (0+)- ERTIGO (0+) MORF : - MULTIPLE ON CNSMORF : - MULTIPLE ON CNS


23/43

METABOLIC DISTR.METABOLIC DISTR.

ETIO : - TOXIETIO : - TOXI

- DEFECIENCY- DEFECIENCY

- METABOLIC DISEASE- METABOLIC DISEASE

FIRST STFIRST ST REERSIBLEREERSIBLE

GENETIC ##GENETIC ##

EXPL : - KERN ICTERUS" LISO1OMAL"EXPL : - KERN ICTERUS" LISO1OMAL"

ENCPTI HEPATIC" ILSON"ENCPTI HEPATIC" ILSON"

REYE SYNDROMEREYE SYNDROME


24/43

CONGTAL DISEASE OF CNSCONGTAL DISEASE OF CNS

2- + X BIRTH2- + X BIRTH

NEURAL TUBE & MAL.FOSA POST. ##NEURAL TUBE & MAL.FOSA POST. ##

ETIO : - GEN MALFORMATIONETIO : - GEN MALFORMATION - MATERNAL INF.- MATERNAL INF.

- RADIATION- RADIATION

- POISON- POISON

- METAB.DISORDER- METAB.DISORDER


25/43

ARNOLD CHIARI SYND.ARNOLD CHIARI SYND.

LOC. : - CEREBELLUMLOC. : - CEREBELLUM

- BRAIN ST.- BRAIN ST. - MED.SP.- MED.SP.

- FOSA POST.- FOSA POST.MENINGO MYEMENINGO MYE

LOCELE.LOCELE.


26/43

DANDY WALKER DISEASEDANDY WALKER DISEASE

FOSA POSTERIORFOSA POSTERIOR

HEMISFERE CEREBELAR (N)" BUT TPHEMISFERE CEREBELAR (N)" BUT TP ERMIS (-)/HIPOPL.ERMIS (-)/HIPOPL.

FOR.EMTR.IFOR.EMTR.I CLOSEDCLOSED


27/43

CONG. D. (OTHER)CONG. D. (OTHER)

AGENESIS/DISGENESISAGENESIS/DISGENESIS

MIGRATION DISTR.& CORTICOGESISMIGRATION DISTR.& CORTICOGESIS DESTRUCTIE LESSIONDESTRUCTIE LESSION

FACOMATOSISFACOMATOSIS

CHOMOSOMAL DISORDERCHOMOSOMAL DISORDER


28/43

CNS DEGENERATIONCNS DEGENERATION

ATAXIA FRIEDREICHATAXIA FRIEDREICH

CEREBELAR CORTEX ATROPHYCEREBELAR CORTEX ATROPHY CER.OLIOPONTO ATROPHYCER.OLIOPONTO ATROPHY

SHY-DRAGER SYNDROMESHY-DRAGER SYNDROME


29/43

MOTOR NEURON DISEASEMOTOR NEURON DISEASE

LAT.AMIOTROPHIC SCLEROTICLAT.AMIOTROPHIC SCLEROTIC

MYONAL ATROPHY PROGRESSIAMYONAL ATROPHY PROGRESSIA BULBAR PALSY PROGRESSIABULBAR PALSY PROGRESSIA

PARKINSON DISEASEPARKINSON DISEASE


30/43

DEMENTIADEMENTIA

ETIOETIO : - D.ORGANIC PRIMER: - D.ORGANIC PRIMER

- CEREBRO ASC.DISEASE- CEREBRO ASC.DISEASE

- INFECTION - I.CR.LESION- INFECTION - I.CR.LESION - HYDROCEPHALUS- HYDROCEPHALUS

- DRUG & TOXIN- DRUG & TOXIN

- METAB.DIS. ' IT.DEFF.- METAB.DIS. ' IT.DEFF.- PARANEOPLASTIC SYNDR.- PARANEOPLASTIC SYNDR.


31/43

DEMENTIADEMENTIA

AL1HEIMERAL1HEIMER PICKPICK

HUNTINGTONHUNTINGTON

PUGILISTICAPUGILISTICA( PUNCH - DRUNK SYNDROMA )( PUNCH - DRUNK SYNDROMA )


32/43

CNS NEOPLASMCNS NEOPLASM

ADULT : - GLIOBLASTOMAADULT : - GLIOBLASTOMA

- MENINGIOMA- MENINGIOMA - ASTROCYTOMA- ASTROCYTOMA

- SCHANOMA- SCHANOMA

- E.T.C.- E.T.C.


33/43


CHILD : - ASTROCYTOMA ##CHILD : - ASTROCYTOMA ##

- MEDULOBLASTOMA ##- MEDULOBLASTOMA ## - EPENDINOMA- EPENDINOMA

- E.T.C- E.T.C


34/43


ETIOETIO : - 3: - 3

FCTRFCTR : - GENETIC: - GENETIC

- CHEMIC- CHEMIC- IRAL- IRAL

- RADIATION- RADIATION

- IMMUN SUPRETION- IMMUN SUPRETION- TRAUMATIC- TRAUMATIC


35/43

PERIPHERAL N. SYSTEM.PERIPHERAL N. SYSTEM.

TYPETYPE : - MYELIN (4): - MYELIN (4)

% ' ,5 MRM% ' ,5 MRM

% SCHAN CELL% SCHAN CELL THICKTHICK

TRANSMITION ##TRANSMITION ##

- MYELIN (-)- MYELIN (-) *"0 - 2 MRM*"0 - 2 MRM

TRANSON $$TRANSON $$


36/43

TRMATIC REAC. P.N.STRMATIC REAC. P.N.S

AXONAL DEG.(ALLERIAN)AXONAL DEG.(ALLERIAN)

SEGMENTAL DEMYELINISATIONSEGMENTAL DEMYELINISATION- PRIMER - ALLERGIC - NEUROPHA- PRIMER - ALLERGIC - NEUROPHA

TIC HYPERTROPHYTIC HYPERTROPHY

DISTAL AXON DEGENERATIONDISTAL AXON DEGENERATION


37/43

PERIPHERE NEUROPATHYPERIPHERE NEUROPATHY

FORMFORM : - MONONEUROPATHY: - MONONEUROPATHY

- M.N.PATHY MULTIPLEX- M.N.PATHY MULTIPLEX - POLYNEUROPATHY- POLYNEUROPATHY

- MIXED- MIXED


38/43

PNS NEOPLASMPNS NEOPLASM

TRAUMATIC NEUROMATRAUMATIC NEUROMA

SCHANNOMASCHANNOMA NEUROFIBROMANEUROFIBROMA

GANGLION CYSTGANGLION CYST

MALIGNANT NEOPLASMMALIGNANT NEOPLASM


39/43

MYONAL NERVE DISTR.MYONAL NERVE DISTR.

NEUROGENICNEUROGENIC

MYIOPATHYMYIOPATHY

NEUROMUSCULAR TRANS.DISTR.NEUROMUSCULAR TRANS.DISTR.


40/43

MYONAL NERVE DISTR.MYONAL NERVE DISTR.

NEUROGENIC :NEUROGENIC :

- MOTOR NEURON- MOTOR NEURON

- MUSK.SPLIS ATROPHY- MUSK.SPLIS ATROPHY- PERIPHER NEUROPATHY- PERIPHER NEUROPATHY

- SPINAL DISTR.(ETC)- SPINAL DISTR.(ETC)


41/43

MOTOR NEURONE DISTR.MOTOR NEURONE DISTR.

DEG. PROGRESIEDEG. PROGRESIE

ANT.HORN MED.SPINALISANT.HORN MED.SPINALIS

ATROPHY DEGENERATIPATROPHY DEGENERATIP FACICULASI & MYONAL EAKNESSFACICULASI & MYONAL EAKNESS


42/43

MUSC.SPINALIS ATROPHYMUSC.SPINALIS ATROPHY

DEGENERATIIE DISEASEDEGENERATIIE DISEASE

HEREDITERHEREDITER

MOTOR NEURONE CNSMOTOR NEURONE CNSTYPE : ," " 2 AND TYPE : ," " 2 AND


43/43

TYPE 1.TYPE 1.

ERDNIGERDNIG

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k7_1.Nervous System(Pa)