Leukocoria 2016fix

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    Diska Astarini

    I11109083

    LEUKOCORIA

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    DEFINITION

    LeukocoriaA wite !u!i""ar# re$e% &"eukos'

    wite( kore' !u!i")( !ink*wite( or#e""ow*wite !u!i""ar# re$ection+

    Nor,a" re$e%  re- re$e%

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    Nor,a" re- re$e%

    Leukocoria .i"atera" Leukocoria uni"atera"

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    Clinical

    diferentials?

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    Leucocoria

    • TUMOR

     –Retinoblastoma (most common cause--58%)

    • D!LO"M#T$L

     –"ersistent &'er'lastic 'rimar& itreous• (nd most common cause--8%)

     –Coats disease (*+%)

     –Retrolental ,bro'lasia (--5%)

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    • .#/CT.O# –Laral 0ranulomatosis (*+%)

    • D1#R$T.! –cataract

    • TR$UM$ –Retino'at& o2 'rematurit& (5%)

     –Lon0-standin0 retinal detacment

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    RETINO/LATOARetino."asto,a is te ,ostco,,on intraocu"ar ,a"i2nantneo!"as, o ci"-oo- a4ectin2

    1'50(000 to 1'36(000 ci"-ren+Te tu,or occurs ,ostre7uent"# witin te rst 5#ears o "ie an- ,a# een .e

    oun- at .irt+

    i2ns' "eukocoria( stra.is,us(!oor ision( s!ontaneous#!e,a( or a re-( !ainu" e#e+

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    RETINO/LATOAA /

    C

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    RETINO/LATOAA /

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    RETINO/LATOATreat,ent o!tion'

    •  Intraenous ce,otera!#•  Enuc"eation

    •  Ra-iation tera!#•  Lasertera!#•  Cr#otera!#

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    RETINO/LATOA * Ce,otera!#

    PRETREATMENT

    a,e "esion atertwo c#c"es o

    ce,otera!#

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    TO;OCARIAITo%ocariasis   a ne,ato-einection (Toxocara canis)

    Retina" -a,a2e is te resu"t o teost

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    TO;OCARIAI

    =resent 'Occu"ar s#,!to,s ' re-ness(!oto!o.ia > !ain+

    Leukocoria( stra.is,us( -ecrease-ision( $oaters+

    O!ta",ic !#sica" e%a,ination '

    A "ar2e !eri!era" &anterior)retina" or coroi- in$a,,ator#,ass( associate- wit aitreoretina" reaction  secon-ar#retina" -etac,ent+

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    TO;OCARIAI

    A white intravitreous mass of a

    toxocaral eosinophilic granuloma

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    CATARACTCataract  an# o!acit# in te "ensFactors ' a2in2( trau,a( to%ins(s#ste,ic -isease &suc as

    -ia.etes)( s,okin2( an- ere-it#+

    Ci"-oo-  con2enita" cataractsi2n '

     "eukocoria a.sent re- !u!i""ar# re$e%  a.nor,a" e#e ,oe,ents&n#sta2,us) tra.is,us

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    COAT? DIEAECon0enital retinal telan0iectasis(Coats3 disease) is an idio'aticretinal ascular disorder tat usuall&

    afects &oun0 male 'atientsunilaterall& in teir ,rst or seconddecade o2 li2e4 No tu,or ,ass+ Retinal telan0iectasia4

    Retinal ca'illar& non'er2usion4 Dilated interca'illar& s'aces4 Li'id e6udate4 7ubretinal uid Retinal detacment

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    COAT? DIEAEA

    A+ Coat?s -isease in ci"-ren/+ ascu"ar a.nor,a"ities wit

    aneur#s,a" -i"atation(

    te"an2iectasia( e%u-ation( an-seere "i!i- -e!osition in te

    /

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    COAT? DIEAE * Treat,ent

     "otocoa0ulation Cr&otera'&

    nucleated   later sta0e seere

    Obliterate

    telangiectasia

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    ETINO=AT@ OF =REATURIT&RO=)

    • Retino'at& o2'rematurit& (RO") 9as2ormerl& :no9n as

    retrolental ,bro'lasia4• Disorder o2 te

    deelo'in0 retinalasculature resultin02rom interru'tion o2normal 'ro0ression o2ne9l& 2ormin0 retinalessels4

    Occurs in teincom letel

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    RIK FACTOR

    •  'rematurit& < lo9 0estational a0e = > 9ee:s• Lo9 birt 9ei0t•

    &'ero6ia < &'o6ia• i0 Li0t e6'osure• !itamin de,cienc&

    • "ostnatal se'sis• Mecanical entilation

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    RETINO=AT@OF =REATURIT &RO=)

    LOCATION Bone 1 *

    centre- on-isc( 5% -isc

    to oea-istance

    Bone 5 * outer"i,it e7uator

    te,!ora""#(ora nasa""#

    Bone 3 *te,!ora"

    !eri!era"crescent

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    RETINO=AT@OF =REATURIT &RO=)

     Treatment @•  Laser 'otocoa0ulation•  Cr&otera'&•  !itrectom& sur0er&

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    TENT @=ER=LATIC =RIARU &=@=)

    "ersistent &'er'lastic 'rimar&itreous (""!) is a con0enitalanomal& in 9ic te 'rimar&itreous 2ails to re0ress in utero4

     i0l& ascular mesenc&mal tissuenurtures te deelo'in0 lens durin0intrauterine li2e4 .n ""!A temesenc&mal tissue (,broascular)2orms a mass beind te lens4

     $ 0ra&-&ello9 retrolental membranema& 'roduce leu:ocoriaA 9it tesubseBuent sus'icion o2

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    =ERITENT @=ER=LATIC=RIAR

    ITREOU &=@=)i2n 'Leukocoria,a"" e#e &,icro!ta",ia)

    E!iso-es o intraocu"ar&intraitreous) e,orra2e+

    Retina" -etac,ent  traction ro, .roascu"ar

    ,ass+

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    NORRIE? DIEAE#orrie diseaseA or te 'ro0ressieoculoacousticocerebral de0enerationo2 #orrieA is a rareA -lin:ed recessie

    eritable disorder caracteri;ed b&bilateral leu:ocoria caused b& retinaldetacment4$fected bo&s classicall& ae a triad

    o2 blindnessA dea2nessA and mentalretardation4 $''arent at birt or inearl& in2anc&A te ocular ,ndin0susuall& 'ro0ress to 'tisis bulbi4

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    RETINAL DETAC@ENT$ retinal detacment (RD)

    describes te se'aration o2 teneurosensor& retina (#7R) 2romte retinal 'i0ment e'itelium

    (R") caused b& a brea:do9n o2te 2orces tat attac te #7R tote R"4

    To%ocariasis( =@=( RO=(Coat?s -isease

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    RETINAL DETAC@ENT

     Treatment@•Cr&otera'&• laser 'otocoa0ulation usin0 a

    slit-lam' delier& s&stem and• laser usin0 te indirecto'talmosco'ic delier& s&stem

    combined 9it scleral indentation4

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    CONCLUION

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    T@ANK OU

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    UETION

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