Life Sciences Statistics 2009- 2010 UNITED KINGDO M

Life Sciences Statistics 2009-2010

UNITED KINGDO

M

About Us

The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology,Pharmaceutical and Medical Device industries. The UK Life Sciences database is a part of Biotechgate.www.biotechgate.comwww.ukbiotech.com

Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.com

Status of the Sector

590 Total Biotechnology Companies

183 Biotech - Therapeutics

358 Biotech – R&D Services

49 Biotech - Other

>32'000 Employees

>1'000 R&D Employees

85% Percentage of SME's

13% Percentage of Companies Publicly Owned

GBP 250 m Financing / Capital Raised

173 Products Available for Out-licensing

Source: www.biotechgate.com

Key Activities of Biotechnology Companies

AgroBio 1%

Bioinformatics and

Bioelectronics 4%Contract

Research and Manufacturing

17%

Cosmetics 1%

Diagnostics and Analytical

Services 19%

Drug Delivery 4%

Environment 2%

Food and Nutraceuticals

1%

Genomics and Proteomics

7%

Industrial Biotechnology

1%

Other Services and

Suppliers 23%

Therapeutics 19%

Veterinary 1%


Biotechnology Companies in the UKBreakdown by subcategory based on 949 entries by 590 companies

Biotechnology Company Size

1-10:27%

11-50:39%

51-250:19%

>25015%

Size of Biotechnology Companies in the UK(by number of employees)

Company Foundation Timeline

710 12

1612 11 11

52

61

9

1817

14

10 14

7

10

85

2

1

1 12

2

0

5

10

15

20

25

30

35

Biotechnology - Therapeutics Biotechnology / R&D Services Biotechnology - other

Company Foundations in the UK


Company Ownership

Private / independent

76%

Public 13%

Subsidiary 11%

Public, Private and Subsidiary Companies in the UK


Sources of Company Foundations

Independent foundation

43%

Management buy-out (MBO)

0.5%Merger

2%

Spin-off from company

4%

Spin-off from public institution /

NPO 2%

Spin-off from university

22%

Subsidiary 18%

Other 9%

Sources of Company Foundations in the UK


Products in the Pipeline

104

45

84

33

0 20 40 60 80 100 120

Discovery & Preclinical

Phase I

Phase II

Phase III


UK Biotechnology Pipeline

5 Largest Therapeutic Biotech Company Financing Rounds

Company Date Currency Amount (millions) Type

Amarin Corporation plc 20.10.2009 USD 70 n/a

Proximagen Neuroscience plc 05.06.2009 GBP 50 Post-IPO

Allergy Therapeutics 12.06.2009 GBP 22.4 Other

Oxagen Limited 24.11.2009 GBP 16 Equity - Second stage

Circassia Limited 11.12.2009 GBP 15 Equity - Later stage


Biotechnology in Selected Countries

Austria Canada France Germany Italy Switzerland U.K.

Biotech companies 75 673 341 801 465 287 590

Therapeutic biotech companies 24 173 79 122 52 70 183

New companies founded in 2009 0 4 5 4 1 5 3

Companies founded 2000 - 2009 39 144 149 270 97 118 197

% of companies with <10 employees 31% 35% 35% 28% 31% 36% 27%

Biotech products in development 51 306 741 225 142 215 266

% publicly listed companies 1% 18% 6% 4% 3% 5% 13%


About Biotechgate

Biotechgate contains over 18’000 high-quality company profiles including company descriptions, contact information, product pipeline information, financing rounds and management details. Profiles are regularly updated by the companies themselves and an experienced database team to ensure the accuracy and relevance of the data.

Monthly Subscription to Biotechgate Companies: EUR 250Annual Subscription to Biotechgate Companies: EUR 1490Annual Subscription to Biotechgate Licensing Deals: EUR 995

To register for free or learn more about the different subscription options, please visit www.biotechgate.com.

Terms of Use

The „UK Life Sciences Survey“ is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation include the figures and information entered in this database and we do not guarantee any accuracy hereof.

A new categorization system was installed during 2007; therefore, subsequent surveys cannot be directly compared with surveys of years prior to 2007.

The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions.

Biotechgatec/o Venture Valuation VV AGKasernenstrasse 11 +41 (43) 321 86 608004 Zurich [email protected] www.venturevaluation.com

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Life Sciences Statistics 2009- 2010 UNITED KINGDO M