Life Sciences Statistics 2009-2010

Life Sciences Statistics 2009-2010

Germany

About Us

The following statistical information has been obtained from Biotechgate. Biotechgate is a global, comprehensive, Life Sciences database encompassing the Biotechnology,Pharmaceutical and Medical Device industries. The GermanLife Sciences database is a part of Biotechgate.www.biotechgate.comwww.germanbiotech.com

Biotechgate is owned and operated by Venture Valuation AG, a Zurich based company specializing in independent assessment and valuation of technology-driven companies in high growth industries, such as the Life Sciences (Biotech, Pharma, Medtech), ICT, high-tech, Nanotech, Cleantech and Renewable energy. www.venturevaluation.com

Status of the Sector

801 Total Biotechnology Companies

122 Biotech - Therapeutics

539 Biotech – R&D Services

140 Biotech - Other

>119'000 Employees

>1'000 R&D Employees

90% Percentage of SME's

4% Percentage of Companies Publicly Owned

EUR 129 m Financing / Capital Raised

151 Products Available for Out-licensing Source: www.biotechgate.com

Key Activities of Biotechnology Companies

AgroBio 4%

Bioinformatics and

Bioelectronics 6%

Contract Research and Manufacturing

12%

Cosmetics 1%

Diagnostics and Analytical

Services 24%Drug Delivery

2%

Environment 3%

Food and Nutraceuticals

3%

Genomics and Proteomics

8%

Industrial Biotechnology

1%

Other Services and Suppliers

27%

Therapeutics 8%

Veterinary 1%

Source: www.biotechgate.com

Biotechnology Companies in GermanyBreakdown by subcategory based on 1468 entries by 801 companies

Biotechnology Company Size

1-10:28%

11-50:47%

51-250:15%

>25010%

Size of Biotechnology Companies in Germany(by number of employees)


Company Foundation Timeline

614 14

6 6 3 6 7 7 4 2

27

41 37

21 24

1418 12

5 81

11

62

2

31

3

1 11

-5

5

15

25

35

45

55

65

Biotechnology - Therapeutics Biotechnology / R&D Services Biotechnology - other

Company Foundations in Germany


Company Ownership

Private / independent

88%

Public 4%

Subsidiary 8%

Public, Private and Subsidiary Companies in Germany


Sources of Company Foundations

Independent foundation

56%

Management buy-out (MBO)

2%

Merger 1%

Spin-off from company

3%

Spin-off from public

institution / NPO 7%

Spin-off from university

15%

Subsidiary 10% Other

6%

Company Foundations in Germany


Products in the Pipeline

122

35

52

16

0 20 40 60 80 100 120 140

Discovery & Preclinical

Phase I

Phase II

Phase III


German Biotechnology Pipeline

5 Largest Therapeutic Biotech Company Financing Rounds (Private Companies Only)

Company Date Currency Amount (millions) Type

Probiodrug AG 02.11.2009 EUR 36 Equity – Start-up stage

Curetis AG 07.12.2009 EUR 18.5 Equity - First stage

Activaero GmbH 29.10.2009 EUR 10.7 Equity - First stage

KeyNeurotek Pharmaceuticals AG 07.04.2009 EUR 8.2 Equity - Second stage

InterMed Discovery GmbH 13.01.2009 EUR 7.44 Equity - Second stage


Biotechnology in Selected Countries

Austria Canada France Germany Italy Switzerland U.K.

Biotech companies 75 673 341 801 465 287 590

Therapeutic biotech companies 24 173 79 122 52 70 183

New companies founded in 2009 0 4 5 4 1 5 3

Companies founded 2000 - 2009 39 144 149 270 97 118 197

% of companies with <10 employees 31% 35% 35% 28% 31% 36% 27%

Biotech products in development 51 306 741 225 142 215 266

% publicly listed companies 1% 18% 6% 4% 3% 5% 13%


About Biotechgate

Biotechgate contains over 18’000 high-quality company profiles including company descriptions, contact information, product pipeline information, financing rounds and management details. Profiles are regularly updated by the companies themselves and an experienced database team to ensure the accuracy and relevance of the data.

To register for free or learn more about the different subscription options, please visit www.biotechgate.com.

Terms of Use

The „German Life Sciences Survey“ is based on data entered in the Biotechgate Database available at www.biotechgate.com. The statistics and graphs in this presentation include the figures and information entered in this database and we do not guarantee any accuracy hereof.

A new categorization system was installed during 2007; therefore, subsequent surveys cannot be directly compared with surveys of years prior to 2007.

The use of the figures and graphs provided in this report is free of charge for any presentations as long as www.biotechgate.com is clearly cited as the source. For all other uses please contact us for terms and conditions.

Biotechgatec/o Venture Valuation VV AGKasernenstrasse 11 +41 (43) 321 86 608004 Zurich [email protected] www.venturevaluation.com

Documents

Life Sciences Statistics 2009-2010