LIMBIC SYSTEMNBIO 401

Friday, December 3, 2010Robinson

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

HYPOTHALAMUS

F igu re 3

anterior posterior

Location of the m edial forebrain bundle in asagittal section of a rat brain.

Hypothalamus

Inputs: -amygdala (via stria terminalis & direct) -hippocampus (via fornix) -septal nuclei (via medial forebrain bundle) -brainstem & spinal cord (via medial forebrain bundle)

Hypothalamus

Outputs: -amygdala (via stria terminalis) -hippocampus (via fornix) -septal nuclei (via medial forebrain bundle) -brainstem & spinal cord sympathetic and parasympathetic preganglionic neurons -pituitary (neural & humoral) -anterior thalamus (to prefrontal, orbital, & cingulate cortex)

INFUNDIBULUM(stalk of pituitary)

OPTICCHIASM

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Amygdala

Inputs: -cortex (orbital, cingulate, entorhinal, & temporal) -hypothalamus (via stria terminalis & directly) -hippocampus -brainstem -septal nuclei -thalamus

Amygdala

Outputs: -cortex (orbital, cingulate, entorhinal, & temporal) -hypothalamus (via stria terminalis & directly) -hippocampus -septal nuclei -thalamus

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Hippocampus

Inputs: -entorhinal cortex (receives input from cingulate, orbital, & prefrontal cortex) -amygdala (via fornix) -hypothalamus (via fornix)

Hippocampus

Outputs: -entorhinal cortex (receives input from cingulate, orbital, & prefrontal cortex) -anterior thalamus (to prefrontal, orbital, & cingulate cortex) -amygdala (via fornix) -hypothalamus (via fornix)

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Cingulate cortex

Inputs:

-VP (somatosensory) thalamus (pain)

-anterior thalamus (to orbital cortex)

-amygdala

Cingulate cortex

Outputs:

-entorhinal cortex

-amygdala

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

(tohippocampus)

Nucleus accumbens

Inputs:

-amygdala

Nucleus accumbens

Outputs:

-basal ganglia

1)Hypothalamus

2)Amygdala

3)Hippocampus

4)Cingulate cortex

5)Nucleus accumbens

6)Septal nuclei

Septal Nuclei

Inputs:

-hippocampus (via fornix)

-amygdala

-medial midbrain reticular formation

Septal Nuclei

Outputs:

-hippocampus (via fornix)

-hypothalamus (via stria terminalis)

-amygdala (via medial forebrain bundle)

Papez Circuit

FIG U R E 14

Ende