LIPID PROFILEBy Micheal and Christian

Quantitative analysis of the lipid metabolism markers in the blood

It includes levels of total cholesterol, LDL, HDL,VLDL, Triglycerides and others

Most of the factors included are considered as risk factors, HDL is a protective factor

What’s Lipid Profile?

A blood sample is taken through venipuncture

Blood is usually obtained for the median cubital vein

It will be analyzed in the lab to determine the quantities of all factors we are interested in

Patient should fast 9-12 hrs before

How is it performed?

The risk of developing coronary heart disease is the major cause for ordering a lipid profile

If the results are normal, it is recommended every five years starting age 20

However if the patient has diabetes, CVD, or Hypertension then it is performed more regularly under a doctor’s surveillance.

When to get one?

LDL : <130mg/dl (lower is better)

VLDL : 2-30 mg/dl

HDL : >40-60 mg/dl (higher is better)

Total Cholesterol : <200 mg/dl

Triglyceride : 10-150 mg/dl (lower is better)

Normal Values

Can be inherited, but preventable and treatable

High correlation with heart disease according to the Framingham Studies

Very dangerous, especially in patients with hypertension, CVD, or diabetes

High Cholesterol, LDL, VLDL, Triglycerides

Obesity Diabetes Hypothyrodism Kidney Disease Lots of alcohol Smoking and sedentary lifestyle Some medications : estrogen, birth control

pills, diuretic

Causes

Good cholesterol

Small new subtype with apo-cIII might increase CVD risks

Anti-thrombotic, anti-inflammatory , anti-sclerotic

We should higher our HDL

HDL

Do not smoke

Exercise

Choose healthy fats

Lose weight

Do not drink alot

How to boost HDL

Fresh Nuts

Fish in general

Olive oil

Avocado and other healthy fats

Oatmeal and fibers

HDL friendly foods

Cholesterol : 310 mg/dl (high > 200)

LDL 241mg/dl (high >130)

HDL : 37 mg/dl (normal)

Triglycerides : 150 mg/dl (Upper boundary at 150)

Our Patient

Therefore one could easily infer that with all the elevated lipid profile indicators, she is at high risk of developing CVD’s

This risk factor combined with others which the patient has (smoking, obesity) should be of the doctor’s interest

She needs management of her risk factors

Our Patient

http://www.nlm.nih.gov/medlineplus/ency/article/003491.htm

http://www.sparkpeople.com/resource/slideshow.asp?show=50

http://www.mayoclinic.com/health/hdl-cholesterol/CL00030

References

Micheal and Christian

THANK YOU