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Load the nodes and modes with query pathway into memory

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START. Load the nodes and modes with query pathway into memory. Retrieve protein sequence for each node. i = i +1, looping. last pathway in pathway_db. no. yes. - PowerPoint PPT Presentation

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Page 1: Load the nodes and modes with query pathway into memory
Page 2: Load the nodes and modes with query pathway into memory
Page 3: Load the nodes and modes with query pathway into memory

Loa

d th

e no

des

and

mod

es w

ith q

uery

pat

hway

in

to m

emor

y i =

i +

1, lo

opin

g

last

pat

hway

in

path

way

_db

Ret

riev

e pr

otei

n se

quen

ce f

or e

ach

node

noye

s

For

each

nod

e, f

ind

orth

ogon

al n

ode

in

the

com

pari

ng p

athw

ay. A

lign

the

mod

es a

nd n

odes

bas

ed o

n th

e or

thog

onal

nod

es

Sort

the

hits

by

over

all s

core

Gen

erat

e ov

eral

l sco

re b

y su

mm

ariz

ing

all t

he m

atch

ed

node

s an

d m

atch

ed m

odes

Gen

erat

e gr

aphi

c ou

tput

Dis

play

the

scre

en

STA

RT

EN

D

Page 4: Load the nodes and modes with query pathway into memory
Page 5: Load the nodes and modes with query pathway into memory

Loa

d th

e no

des

and

mod

es w

ith q

uery

pat

hway

into

m

emor

y

j = j

+1,

loop

ing

for

all p

rote

in n

odes

last

pro

tein

in

quer

y pa

thw

ay

in

pa

thw

ay_d

b

Ret

riev

e pr

otei

n se

quen

ce f

or e

ach

node

noye

s

For

each

nod

e, B

LA

STp

vs. p

rote

in_d

b to

fin

d or

thog

onal

nod

e in

the

mat

chin

g sp

ecie

sFi

t eac

h or

thol

ogou

s pr

otei

n in

to th

e hi

t pa

thw

ay, i

nher

it al

l int

erac

tion

mod

es

Stor

e th

ose

top-

hits

in th

e m

atch

ing

spec

ies

that

is a

bove

thre

shol

dFo

r ea

ch m

atch

ing

spec

ies,

gen

erat

e gr

aphi

c ou

tput

Dis

play

on

the

scre

en a

ccor

ding

to th

e or

der

of o

vera

ll sc

ore

STA

RT

E

ND