MATERI GENETIK, ALUR INFORMASI GENETIK DAN …blog.ub.ac.id/puspitt/files/2012/12/topik2.EDIT_.-materi-genetik... · KROMOSOM Jumlah kromosom Setiap sel somatik mengandung satu set

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  • MATERI GENETIK, ALUR INFORMASIGENETIK DAN EKSPRESI GEN

  • THE CHEMICAL NATURE OF THEGENETIC MATERIAL

    The genetic material is consisted of :

    Chromosomes

    Genes

    called as NUCLEOPROTEIN

    reside along the chromosome

  • KROMOSOM

    Jumlah kromosom Setiap sel somatik mengandung satu set

    kromosom yg diwariskan dr induk maternal(betina) dan satu set kromosom pasangannya(kromosom homolog) dr induk paternal(jantan) Set rangkap disebut DIPLOID (2n) gamet (1/2 dr sel somatis, HAPLOID (n)

    Jumlah kromosom Setiap sel somatik mengandung satu set

    kromosom yg diwariskan dr induk maternal(betina) dan satu set kromosom pasangannya(kromosom homolog) dr induk paternal(jantan) Set rangkap disebut DIPLOID (2n) gamet (1/2 dr sel somatis, HAPLOID (n)

  • Chromosomes

    The essential part of a chromosomeis a single very long strand of DNA.This DNA contains all the geneticinformation for creating and runningthe organism.

    The DNA is supported and neatlypackaged by proteins bound to it.At different times, these proteinscause the DNA to be spread out likespaghetti in a bowl, or tightlycondensed into the X-shapedchromosomes we can see in themicroscope.

    Each chromosome has a centralconstricted region called acentromere that serves as anattachment point for the machineryof mitosis.

    The essential part of a chromosomeis a single very long strand of DNA.This DNA contains all the geneticinformation for creating and runningthe organism.

    The DNA is supported and neatlypackaged by proteins bound to it.At different times, these proteinscause the DNA to be spread out likespaghetti in a bowl, or tightlycondensed into the X-shapedchromosomes we can see in themicroscope.

    Each chromosome has a centralconstricted region called acentromere that serves as anattachment point for the machineryof mitosis.

  • Morfologi Kromosom

  • Chromosome in generalChromosome in general(size, shape and number)(size, shape and number)

    - Diploid organisms = 2n- Two copies of autosomes

    with sex chromosomes- diploid organisms have two cell-types

    somatic cells = bodys cellsgerm cells = gametes

    - human bodies ~= 1014 cellsmany cell divisions => mitosis

    - sexual reproductionrequire haploid (n) cells => meiosis

    - Diploid organisms = 2n- Two copies of autosomes

    with sex chromosomes- diploid organisms have two cell-types

    somatic cells = bodys cellsgerm cells = gametes

    - human bodies ~= 1014 cellsmany cell divisions => mitosis

    - sexual reproductionrequire haploid (n) cells => meiosis

    Human chromosomes =22 pairs of autosomes + sex chromosome (XX or XY)

  • Double helix DNA

  • GENE EXPRESSION

    DNA

    RNA POPULATION

    BIOSPHERIC PHENOTYPE

    PROTEIN

    CELL EFFECT TISSUE

    ORGANISM

  • DNA

    DNA Replication

    CENTRAL DOGMAFrancis Crick, 1958

    DNA

    RNA PROTEIN

    Transcription

    Translation

  • TRANSCRIPTION

  • REMOVALOF INTRONS