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OCTOBER 2020, ISSUE 88 WELCOME As we head into the nal month of autumn, we've seen somewhat of an upswing in activity as we all adjust to the new virtual and remote event paradigms. We would like to thank everyone who joined us for analytica virtual 2020 and those who made our own event presented by Rigaku Analytical Devices—Transforming workows with handheld Raman—success. Also, a special thank you to those who joined us for our Virtual XRF School. Our next session will be held Jan. 26–28, 2021. You can view more details and register here. November also promises to be a productive month. On Nov. 9–10, the Product Quality Research Institute (PQRI) will host the live virtual 4th PQRI Workshop on ICH Q3D Elemental Impurities Requirements. As the implementation of the ICH Q3D guideline went into full effect in the United States and Europe in 2018 for all pharmaceutical products, this workshop will provide an overview of—and update on—implementation experiences since the 2017 PQRI Workshop and review ongoing work in the industry to resolve challenges involved in the global implementation of Elemental Impurities (EI) guidelines and standards. Our XRF applications scientists, Glenn Williams, Ph.D. and Thanh Nguyen, Ph.D will be presenting XRF data for the PQI Phase 2 Elemental Impurity Collaborative Study from 11:45 AM–12:15 PM on Nov. 10. You can register here. In the meantime, we present the latest news and applications in X-ray material science. Enjoy! UPCOMING RIGAKU EVENTS MS&T 2020 November 2–6, 2020 Virtual Event JASIS 2020 November 11–13, 2020 Tokyo, Japan IPMI 44th Annual Conference November 16–17, 2020 Virtual Event VIEW MORE UPCOMING RIGAKU WEBINARS TOPIQ | Rigaku EDXRF Analyzers in the Petroleum Industry November 10, 9 AM and 8 PM | CDT In this webinar, we highlight Rigaku EDXRF analyzers used upstream, midstream and downstream in the petroleum industry for the measurement of sulfur, chlorine and metals in crude and fuel oils, including automotive, aviation and marine fuels. Lubricating oils are also discussed, followed by a summary of the ASTM and other international standard test methods covered by the Rigaku EDXRF product line. Read More > X-ray Computed Tomography for Materials & Life Sciences 8: Metrology Applications December 16, 1 PM | CDT Basics of metrology analysis and a number of X-ray CT application examples will be discussed. Examples include size and shape measurements of metal and plastic parts, tolerancing evaluation, comparison of nominal (CAD) and actual (CT) or a golden standard and a test subject. We will also introduce available resources to learn more about X-ray CT metrology. Read More > VIEW MORE FEATURED JOURNALS & REPORTS Defect structure analysis in single crystal substrates using XRTmicron By Katsuhiko Inaba, Rigaku Corporation For more than 50 years, X-ray topography (XRT) has been an indispensable industrial and research tool for crystal growth of functional materials, since crystalline defects, such as dislocations, stacking faults, etc., can be detected with this technique non-destructively. Industrial demand for almost dislocation-free Si has greatly contributed to this technique, providing important insights for the improvement of crystal quality. Read More > FEATURED PRODUCTS XRTmicron Rigaku XRTmicron is a fast, high-resolution laboratory X-ray topography system for non- destructive dislocation imaging. Various types of dislocations and non-uniformity within single crystal wafers (such as Si, SiC, GaN, Ge, GaAs, quartz, sapphire, rutile, calcium uoride etc.) can be imaged across wafers up to 300 mm in diameter. X-ray topography is a widely used dislocation analysis technique for both research and development and process control by various single crystal, wafer and device manufacturers. Read More > NANOPIX mini Rigaku NANOPIX mini is the world's rst benchtop small-angle X-ray scattering (SAXS) system that is engineered to deliver automatic nanoparticle size distribution analysis for both quality control and research and development applications. Nanoparticle size, size distribution, and particle shape are the key pieces of information obtained from SAXS. Read More > FEATURED APPLICATION NOTES Lead Analysis in Gasoline Rigaku Corporation Lead (Pb), in the form of alkyl lead such as tetraethyl lead, used to be added to gasoline as an antiknock additive to increase the octane rating. However, alkyl lead is highly poisonous. Gasoline with alkyl lead, called leaded gasoline, causes air pollution. Nowadays, most countries, except in Africa, ban leaded gasoline for vehicles. Alkyl lead is still used as an additive in aviation gasoline. Read More > Organic Chlorides in Crude Applied Rigaku Technologies Chlorides in crude contribute to corrosion in the piping at reneries during cracking as well as mid-stream in pipelines. Organic chlorides do not naturally occur in crude; however, inorganic chlorides in the form of salts as well as residual organic chlorides from various natural sources as well as adulteration can contaminate crude. Contracts at the pipelines may contain clauses limiting the amount of organic chloride allowed in the crude. Read More > Polymorph Monitoring with the Rigaku Progeny 1064 nm Handheld Raman Analyzer Rigaku Analytical Devices Polymorphs are chemicals with the same atomic components but the physical arrangement of the molecules differ. The differences in their structures cause polymorphs to behave differently—and within the pharmaceutical industry—this means bioavailability changes. It is important to differentiate polymorph types in any pharmaceutical formulation because a change in the polymorph will affect physical properties from particle size to solubility and have distinct impact on bioavailability of the drug. Read More > FEATURED VIDEO & USEFUL LINK OF THE MONTH Synchrotron X-ray Diffraction Analysis Learn about the work and facilities in X-ray diffraction at the Centre for Nano Production and Micro Analysis at the Danish Technological Institute. Polymer Properties Database This web-based library gives a brief overview of the most common resins, plastics and elastomers, their properties, uses, and manufacture. It also provides information about products made of plastics like bers, textiles, lms, seals and products that are formulated with resins like adhesives, sealants, and coatings. MATERIALS ANALYSIS IN THE NEWS September 22, 2020: Electrochemical reactions, which will play an important role in the future of energy supply, can now be explained in detail, thanks to measurements carried out by TU Wien and DESY. A special material made of lanthanum, strontium, iron and oxygen can be switched back and forth between two different states: In one state the material is catalytically extremely active, in the other less so. September 22, 2020: PSI scientists have gained a fundamental understanding of a highly promising material that could be suited to future data storage applications. Their experiments with strontium-iridium oxide, Sr 2 IrO 4 , investigated both the magnetic and electronic properties of the material as a thin lm. The study was enabled by sophisticated X-ray scattering, a technology where PSI researchers are amongst the world experts. The results are published in the journal Proceedings of the National Academy of Sciences. September 22, 2020: The term "quantum materials" was introduced to highlight the exotic properties of unconventional superconductors, heavy-fermion systems and multifunctional oxides, but the denition has broadened in recent times. With this in mind, "The 2020 Quantum Materials Roadmap" review has been published in Journal of Physics: Materials. October 1, 2020: Technion researchers have developed accurate radiation sources that are expected to lead to breakthroughs in a variety of elds, including the analysis of chemicals and biological materials, medical imaging, X-ray equipment for security screening, and other uses of accurate X-ray sources. October 1, 2020: A Hokkaido University research group has successfully demonstrated that carbon-carbon (C-C) covalent bonds expand and contract exibly in response to light and heat. The team found bond exibility by designing and synthesizing an organic compound that self-assembles into a cage-like structure when exposed to light. They then focused on the bond length between two particular carbon atoms at the molecule's core using X-ray analysis and Raman spectroscopy, and found this cyclization process had contracted this bond. October 1, 2020: Materials scientists at Imperial College have contributed to two Henry Royce Institute-led roadmaps detailing how to reach net-zero carbon emissions by 2050. October 14, 2020: Researchers from POSTECH demonstrate a novel physical phenomenon by controlling variations of the atomic structure. They have revealed the mechanism behind making materials used in new memory devices by using articial intelligence. October 15, 2020: Magnesium silicide (Mg 2 Si) is a thermoelectric material that can convert heat into electricity. Though it is known that adding antimony impurities enhances the performance of Mg 2 Si, the mechanisms underlying this effect are unclear. Now, scientists from Japan shed light on the effects of these impurities at the atomic level, taking us closer to arriving at a practical way of eciently harvesting waste heat from cars and thermal power plants to produce clean energy. October 16, 2020: A research group led by Prof. Zhang Yongsheng from the Institute of Solid State Physics, Hefei Institutes of Physical Science successfully explained the novel physical mechanisms behind pyrite-type ZnSe 2 . October 13, 2020: Researchers at Penn State and the University of Cincinnati received a $500,000 National Science Foundation (NSF) grant to advance quality control methods for parts produced through additive manufacturing, or 3D printing. The grant will support three years of experimental research and model development. Subscribe to Rigaku newsletters! 2020 — Rigaku Corporation and its Global Subsidiaries. All Rights Reserved. 9009 New Trails Drive, The Woodlands, TX 77381, United States

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  • OCTOBER 2020, ISSUE 88

    WELCOME

    As we head into the �nal month of autumn, we've seen somewhat of an upswing in activity aswe all adjust to the new virtual and remote event paradigms. We would like to thank everyonewho joined us for analytica virtual 2020 and those who made our own event presented byRigaku Analytical Devices—Transforming work�ows with handheld Raman—success.

    Also, a special thank you to those who joined us for our Virtual XRF School. Our next sessionwill be held Jan. 26–28, 2021. You can view more details and register here.

    November also promises to be a productive month. On Nov. 9–10, the Product QualityResearch Institute (PQRI) will host the live virtual 4th PQRI Workshop on ICH Q3D ElementalImpurities Requirements. As the implementation of the ICH Q3D guideline went into full effectin the United States and Europe in 2018 for all pharmaceutical products, this workshop willprovide an overview of—and update on—implementation experiences since the 2017 PQRIWorkshop and review ongoing work in the industry to resolve challenges involved in the globalimplementation of Elemental Impurities (EI) guidelines and standards.  Our XRF applications scientists, Glenn Williams, Ph.D. and Thanh Nguyen, Ph.D will bepresenting XRF data for the PQI Phase 2 Elemental Impurity Collaborative Study from 11:45AM–12:15 PM on Nov. 10. You can register here.

    In the meantime, we present the latest news and applications in X-ray material science.

    Enjoy!

    UPCOMING RIGAKU EVENTS

    MS&T 2020  November 2–6, 2020

     Virtual Event

    JASIS 2020 November 11–13, 2020

     Tokyo, Japan

    IPMI 44th AnnualConference

    November 16–17, 2020Virtual Event

    VIEW MORE

    UPCOMING RIGAKU WEBINARS

    TOPIQ | Rigaku EDXRF Analyzers in the Petroleum IndustryNovember 10, 9 AM and 8 PM | CDTIn this webinar, we highlight Rigaku EDXRF analyzers used upstream, midstream anddownstream in the petroleum industry for the measurement of sulfur, chlorine and metals incrude and fuel oils, including automotive, aviation and marine fuels. Lubricating oils are alsodiscussed, followed by a summary of the ASTM and other international standard testmethods covered by the Rigaku EDXRF product line.Read More >

    X-ray Computed Tomography for Materials & Life Sciences 8: MetrologyApplicationsDecember 16, 1 PM | CDTBasics of metrology analysis and a number of X-ray CT application examples will bediscussed. Examples include size and shape measurements of metal and plastic parts,tolerancing evaluation, comparison of nominal (CAD) and actual (CT) or a golden standardand a test subject. We will also introduce available resources to learn more about X-ray CTmetrology.Read More >

    VIEW MORE

    FEATURED JOURNALS & REPORTS

    Defect structure analysis in single crystalsubstrates using XRTmicronBy Katsuhiko Inaba, Rigaku Corporation

    For more than 50 years, X-ray topography (XRT) has been anindispensable industrial and research tool for crystal growthof functional materials, since crystalline defects, such asdislocations, stacking faults, etc., can be detected with thistechnique non-destructively. Industrial demand for almostdislocation-free Si has greatly contributed to this technique,providing important insights for the improvement of crystalquality.Read More >

    FEATURED PRODUCTS

    XRTmicron

    Rigaku XRTmicron is a fast, high-resolutionlaboratory X-ray topography system for non-destructive dislocation imaging. Varioustypes of dislocations and non-uniformitywithin single crystal wafers (such as Si, SiC,GaN, Ge, GaAs, quartz, sapphire, rutile,calcium �uoride etc.) can be imaged acrosswafers up to 300 mm in diameter. X-raytopography is a widely used dislocationanalysis technique for both research anddevelopment and process control by varioussingle crystal, wafer and devicemanufacturers.Read More >

    NANOPIX mini

    Rigaku NANOPIX mini is the world's �rstbenchtop small-angle X-ray scattering(SAXS) system that is engineered to deliverautomatic nanoparticle size distributionanalysis for both quality control and researchand development applications. Nanoparticlesize, size distribution, and particle shape arethe key pieces of information obtained fromSAXS.Read More >

    FEATURED APPLICATION NOTES

    Lead Analysis in GasolineRigaku Corporation

    Lead (Pb), in the form of alkyl lead such as tetraethyl lead,used to be added to gasoline as an antiknock additive toincrease the octane rating. However, alkyl lead is highlypoisonous. Gasoline with alkyl lead, called leaded gasoline,causes air pollution. Nowadays, most countries, except inAfrica, ban leaded gasoline for vehicles. Alkyl lead is still usedas an additive in aviation gasoline.Read More >

    Organic Chlorides in CrudeApplied Rigaku Technologies

    Chlorides in crude contribute to corrosion in the piping atre�neries during cracking as well as mid-stream in pipelines.Organic chlorides do not naturally occur in crude; however,inorganic chlorides in the form of salts as well as residualorganic chlorides from various natural sources as well asadulteration can contaminate crude. Contracts at thepipelines may contain clauses limiting the amount of organicchloride allowed in the crude.Read More >

    Polymorph Monitoring with the Rigaku Progeny1064 nm Handheld Raman AnalyzerRigaku Analytical Devices

    Polymorphs are chemicals with the same atomic componentsbut the physical arrangement of the molecules differ. Thedifferences in their structures cause polymorphs to behavedifferently—and within the pharmaceutical industry—thismeans bioavailability changes. It is important to differentiatepolymorph types in any pharmaceutical formulation becausea change in the polymorph will affect physical properties fromparticle size to solubility and have distinct impact onbioavailability of the drug.Read More >

    FEATURED VIDEO & USEFUL LINK OF THEMONTH

    Synchrotron X-ray Diffraction Analysis

    Learn about the work and facilities in X-raydiffraction at the Centre for Nano Productionand Micro Analysis at the DanishTechnological Institute.

    Polymer Properties Database

    This web-based library gives a briefoverview of the most common resins,plastics and elastomers, their properties,uses, and manufacture. It also providesinformation about products made ofplastics like �bers, textiles, �lms, seals andproducts that are formulated with resinslike adhesives, sealants, and coatings.

    MATERIALS ANALYSIS IN THE NEWS

    September 22, 2020: Electrochemical reactions, which will play an important role in the futureof energy supply, can now be explained in detail, thanks to measurements carried out by TUWien and DESY. A special material made of lanthanum, strontium, iron and oxygen can beswitched back and forth between two different states: In one state the material is catalyticallyextremely active, in the other less so.

    September 22, 2020: PSI scientists have gained a fundamental understanding of a highlypromising material that could be suited to future data storage applications. Their experimentswith strontium-iridium oxide, Sr2IrO4, investigated both the magnetic and electronic properties

    of the material as a thin �lm. The study was enabled by sophisticated X-ray scattering, atechnology where PSI researchers are amongst the world experts. The results are published inthe journal Proceedings of the National Academy of Sciences.

    September 22, 2020: The term "quantum materials" was introduced to highlight the exoticproperties of unconventional superconductors, heavy-fermion systems and multifunctionaloxides, but the de�nition has broadened in recent times. With this in mind, "The 2020 QuantumMaterials Roadmap" review has been published in Journal of Physics: Materials.

    October 1, 2020: Technion researchers have developed accurate radiation sources that areexpected to lead to breakthroughs in a variety of �elds, including the analysis of chemicalsand biological materials, medical imaging, X-ray equipment for security screening, and otheruses of accurate X-ray sources.

    October 1, 2020: A Hokkaido University research group has successfully demonstrated thatcarbon-carbon (C-C) covalent bonds expand and contract �exibly in response to light andheat. The team found bond �exibility by designing and synthesizing an organic compoundthat self-assembles into a cage-like structure when exposed to light. They then focused on thebond length between two particular carbon atoms at the molecule's core using X-ray analysisand Raman spectroscopy, and found this cyclization process had contracted this bond.

    October 1, 2020: Materials scientists at Imperial College have contributed to two Henry RoyceInstitute-led roadmaps detailing how to reach net-zero carbon emissions by 2050.

    October 14, 2020: Researchers from POSTECH demonstrate a novel physical phenomenon bycontrolling variations of the atomic structure. They have revealed the mechanism behindmaking materials used in new memory devices by using arti�cial intelligence.

    October 15, 2020: Magnesium silicide (Mg2Si) is a thermoelectric material that can convert

    heat into electricity. Though it is known that adding antimony impurities enhances theperformance of Mg2Si, the mechanisms underlying this effect are unclear. Now, scientists

    from Japan shed light on the effects of these impurities at the atomic level, taking us closer toarriving at a practical way of e�ciently harvesting waste heat from cars and thermal powerplants to produce clean energy.

    October 16, 2020: A research group led by Prof. Zhang Yongsheng from the Institute of SolidState Physics, Hefei Institutes of Physical Science successfully explained the novel physicalmechanisms behind pyrite-type ZnSe2.

    October 13, 2020: Researchers at Penn State and the University of Cincinnati received a$500,000 National Science Foundation (NSF) grant to advance quality control methods forparts produced through additive manufacturing, or 3D printing. The grant will support threeyears of experimental research and model development.

    Subscribe to Rigaku newsletters!

    2020 — Rigaku Corporation and its Global Subsidiaries. All Rights Reserved.

    9009 New Trails Drive, The Woodlands, TX 77381, United States

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