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Materials and Engineering ScienceMaterials and Engineering ScienceANSTOANSTO
website:website:http://www.ansto.gov.au/ansto/matengsci/index.htmlhttp://www.ansto.gov.au/ansto/matengsci/index.html
Suzanne V SmithSuzanne V Smith
[email protected]@ansto.gov.au
Radioanalytical and Chemical Radioanalytical and Chemical AnalysisAnalysis
Expertise
• Experience in development of targetry,
design and execution of radiotracer studies.
• Development of routine methods and training
in use of relevant techniques is also
available.
Radioanalytical and Chemical Radioanalytical and Chemical AnalysisAnalysis
Facilities
• Gamma counter – (0 - 2000 keV; small and large sampling)
• Alpha, beta and gamma spectrometry – (28 and 50% efficiency)
• Graphite furnace atomic absorption spectroscopy
• Inductively coupled plasma-mass spectrometry (ICP-MS), and
• Clean room facilities.
Nanotechnology Nanotechnology Controlled Release of Drugs.Controlled Release of Drugs.
≈ 20 m
Novel technology for production nanoparticles.
Encapsulation and release of molecules under controlled conditions≈ 0.05 m
Selective Inorganic SorbentsSelective Inorganic Sorbents
Microporous inorganic adsorbents that have unique metal ion binding affinity.
Investigating their application for radioisotope separation.
Images: Alexandra Bush
Image: Victor Luca
MicrobiologyMicrobiology
• Research/synthesis of bio-inorganic
composites (live rocks).• Characterisation of biological systems.
• Culturing of fastidious microbes -
magnetotactic bacteria
• Novel bioreactors – culturing cells requiring
high pO2
– E.g hepatocytes
Top: magnetotactic bacterium with a chain of magnetosomes (dark inclusions).
Bottom: higher magnification of the magnetosomes in the cell. Images from Tony Taylor
Integrated Suite of Characterisation Integrated Suite of Characterisation Capabilities and ExpertiseCapabilities and Expertise
• Scanning electron microscopy (SEM)• spatial/topological info., resolution 3.5 nm• chemical info., spatial limit ~1 micron
• Transmission electron microscopy (TEM)• spatial/structural/topological info., resolution 0.1 nm• chemical/valence/bonding info., spatial limit ~10 nm
• Structure and texture analysis•X-ray diffraction (XRD) •Neutron diffraction
• Nuclear Magnetic Resonance Spectroscopy (NMR)
•Atomic force microscopy (AFM)
International Collaborations International Collaborations Radiometal tracersRadiometal tracers
Apply ANU/ANSTO patent - radiolabelling technology – Harvard Medical School, USA – Humanized
Antibodies– Cambridge University, UK – Humanized
Antibodies– TRIUMF, Canada – RNA
Apply ANSTO Radioplatinum Patent Technology– Paterson Cancer Institute, UK– Harvard Medical School, USA– NECSA, South Africa