1
The 1 Marquette University, Amader Gram 2 Md Kamrul Hasan 1 , GM Tanimul Ahsan 1 , Amit Kumar Saha 1 , Sheikh Iqbal Ahmed 1 , Richard Love 2 Blood sample from heel prick Photo courtesy of Chitose Suzuki for Boston University Photography Step 1: Collect the data from finger tip, ear helix, hand, and lip Send these spectra from the spectrometer to mobile using Bluetooth. If the spectrometer has Wi-Fi support then we can send the data directly to the cloud. Step 2: If smart phone receives the spectra then it will preprocess the data and send to the cloud for decision making Step 3: The cloud computer run the algorithm and send the decision within very short period of time to the smart phone app. Mobile application will show the result to the user, store the data for the future. System Architecture Hemoglobin (Hb) level is an important bio-marker for evaluating health condition. Thalassemia and sickle cell diseases are most common genetic diseases. Sickle cell patients and premature infants who have anemia need to check their hemoglobin level very frequently. Motivation Current invasive Hb measurement technology does venipuncture. Blood tests need the blood sample in medical laboratories. It requires laboratory equipment and facilities, specific specimen of blood, cost and time. Spectrum analysis give higher accuracy level value. Small size spectrometer are available in the market. Finger tip, ear helix, hand and lower lip are considered as expected location to collect spectrum. Proposed Data Collection System Develop smartphone supported mobile spectrometer. That can be easily attached with smartphone camera Make the device cheaper and affordable Mobile app to collect, preprocess the data. Our Vision: Mobile Supported Cheap Hardware and Accurate Result Blood sample from finger tip Optical fiber probe will be used UV-vis range light is considered Wavelength 300nm – 700nm Light absorption technology 12.5 g/dL HB Level Develop the mobile spectrometer that will be Cheaper and user friendly Easily attached with mobile cover Able to collect the spectrum faster Able to send accurate data using the mobile app Final Goal Cloud based solution for Data collection Response to mobile devices Algorithm design Maintain privacy and security This pictures are taken from internet as dummy presentation. Data Analysis Spectrum data can be transferred to computer through USB. Noise free spectra are considered Absorption picks are evaluated Personalized data are analyzed in this phase Second Phase: Build the System and Algorithm Algorithm Design Machine learning algorithms are applied For each person, spectra from different locations are considered Other physiological data like age, gender, blood pressure, heart beat are also recorded Blood Spectrum Collection Spectrum data are taken from liquid blood of each person. Different dilution of liquid blood are tested. Spectrometer will be used for spectrum collection First Phase: Develop the Fundamental Theory Data Analysis and Algorithm Design Matlab tools are used Outlier data are removed Mathematical model are made Algorithmic steps are determined Test the result with original Hb level 12.5 g/dL HB Level 1 12.5 g/dL HB Level 3 2 Cloud computer and database Data collection should be easier Spectrum needs to be accurate Preprocessing should be faster Data transfer and result shown should be with in couple of second Better result (~95% accuracy) The Poster is presented in IEEE Computers, Software, and Applications Conference Poster Session (COMPSAC 2016), Atlanta, Georgia, USA June 10-14, 2016 Disclaimer: The pictures are dummy and used to understand what type of device are planning to make for the end users. We are aiming to make the devices cheaper and user friendly. Thanks to the authorities for sharing these pictures in Google. Spectrum from finger tip Spectrum from ear helix Spectrum from hand Spectrum from lip Desktop computer will process the data using machine learning algorithm Spectrum are sent to mobile application Preprocessed data are sent to cloud Response from the cloud Dummy Picture-II : We can build the mobile spectrometer and put it inside the mobile cover that will allow us to easily attached with smart phone. Dummy Picture-I : We can develop a separate spectrometer having this shape so that we can attach it in front of the mobile camera. Image source: nbcnews.com Image source: verisante.com/aura/ Photo by Chitose Suzuki Photo by Chitose Suzuki

Md Kamrul Hasan , GM Tanimul Ahsan , Amit Kumar Saha

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The

1Marquette University, Amader Gram2

M d K a m r u l H a s a n 1 , G M Ta n i m u l A h s a n 1 , A m i t K u m a r S a h a 1 , S h e i k h I q b a l A h m e d 1 , R i c h a r d L o v e 2

Blood sample from heel prick

Photo courtesy of Chitose

Suzuki for Boston University

Photography

Step 1:• Collect the data from finger tip, ear helix,

hand, and lip

• Send these spectra from the spectrometer to

mobile using Bluetooth.

• If the spectrometer has Wi-Fi support then we

can send the data directly to the cloud.

Step 2:

• If smart phone receives the spectra then it

will preprocess the data and send to the

cloud for decision making

Step 3:

• The cloud computer run the algorithm and

send the decision within very short period

of time to the smart phone app.

• Mobile application will show the result to

the user, store the data for the future.

System Architecture

• Hemoglobin (Hb) level is an

important bio-marker for

evaluating health condition.

• Thalassemia and sickle cell

diseases are most common

genetic diseases.

• Sickle cell patients and

premature infants who have

anemia need to check their

hemoglobin level very

frequently.

Motivation• Current invasive Hb

measurement technology does

venipuncture.

• Blood tests need the blood

sample in medical laboratories.

• It requires laboratory equipment

and facilities, specific specimen

of blood, cost and time.

• Spectrum analysis give higher

accuracy level value.

• Small size spectrometer are

available in the market.

• Finger tip, ear helix, hand

and lower lip are considered

as expected location to

collect spectrum.

Proposed Data Collection System• Develop smartphone supported mobile

spectrometer.

• That can be easily attached with

smartphone camera

• Make the device cheaper and affordable

• Mobile app to collect, preprocess the data.

Our Vision: Mobile Supported Cheap Hardware and Accurate Result

Blood sample from finger tip

• Optical fiber probe will be used

• UV-vis range light is considered

• Wavelength 300nm – 700nm

• Light absorption technology

12.5g/dL

HB Level

• Develop the mobile spectrometer that will be • Cheaper and user friendly

• Easily attached with mobile cover

• Able to collect the spectrum faster

• Able to send accurate data using the mobile app

Final Goal

• Cloud based solution for• Data collection

• Response to mobile devices

• Algorithm design

• Maintain privacy and security

This

pic

ture

s are

taken f

rom

inte

rnet

as

dum

my p

rese

nta

tion.

• Data Analysis• Spectrum data can be transferred to

computer through USB.

• Noise free spectra are considered

• Absorption picks are evaluated

• Personalized data are analyzed in this phase

Second Phase: Build the System and Algorithm• Algorithm Design

• Machine learning algorithms are applied

• For each person, spectra from different

locations are considered

• Other physiological data like age, gender,

blood pressure, heart beat are also recorded

• Blood Spectrum Collection • Spectrum data are taken from liquid blood

of each person.

• Different dilution of liquid blood are tested.

• Spectrometer will be used for spectrum

collection

First Phase: Develop the Fundamental Theory

• Data Analysis and Algorithm Design• Matlab tools are used

• Outlier data are removed

• Mathematical model are made

• Algorithmic steps are determined

• Test the result with original Hb level

12.5g/dL

HB Level

112.5g/dL

HB Level

3 2

Cloud computer and database

• Data collection should be easier

• Spectrum needs to be accurate

• Preprocessing should be faster

• Data transfer and result shown should be

with in couple of second

• Better result (~95% accuracy)

The Poster is presented in IEEE Computers, Software, and Applications

Conference Poster Session (COMPSAC 2016), Atlanta, Georgia, USA

June 10-14, 2016

Disclaimer: The pictures are dummy and used to understand what type of device are planning to make for the end users. We are aiming to make the devices cheaper

and user friendly. Thanks to the authorities for sharing these pictures in Google.

Spectrum from finger tip Spectrum from ear helix

Spectrum from hand Spectrum from lip

Desktop computer will process the data

using machine learning algorithm

Spectrum are sent to

mobile application

Preprocessed data

are sent to cloud

Response from

the cloud

Dummy Picture-II : We can build the mobile spectrometer and put it inside the mobile cover that will allow us to easily attached with smart phone.

Dummy Picture-I : We can develop a separate spectrometer having this shape so that we can attach it in front of the mobile camera.

Image source: nbcnews.com

Image s

ourc

e:

veri

sante

.com

/aura

/

Photo by Chitose Suzuki

Photo by Chitose Suzuki