Missiles are often cited with their maximum engagement range, which is very misleading. A missile's effective range is dependent on factors such as altitude, speed, position, and direction of the target aircraft as well as those of the attacking aircraft. For example the Vympel R-77 has stated range of 100 km. That is only true for a head-on, non-evading target at high altitude. At low altitude, the effective range is reduced by as much as 75%–80% to 20–25 km. If the target is taking evasive action, or in stern-chase position, the effective range is further reduced. See Air-to-Air missile non-comparison table for more information. The effective range of an air-to-air missile is known as the "no-escape zone", noting the range at which the target can not outrun the missile once launched.

Poorly-trained pilots are known to fire their missiles at maximum-range engagement with poor results. In the 1998–2000 Eritrean-Ethiopian War, fighters from both sides shot over a dozen medium-range R-27 (AA-10 Alamo) missiles at distance with little effect. But when better-trained Ethiopian Su-27 pilots gave chase and attacked with short-range R-73 (AA-11 Archer) missiles, the results were often deadly to the Eritrean aircraft. [1]

A missile is also subject to a minimum range, before which it cannot maneuver effectively. In order to maneuver sufficiently from a poor launch angle at short ranges to hit its target, some missiles use thrust vectoring, which allow the missile to start turning "off the rail", before its motor has accelerated it up to high enough speeds for its small aerodynamic surfaces to be useful.