Sex-linked Traits with The Flintstones

Geneticists have succeeded in sequencing the genes on the sex chromosomes of Bedrock’s most famous couple, Fred and Wilma Flintstone. Shocking discoveries have been made - the secrets of Bedrock can now be revealed!

Directions: Analyze Figure 1 to identify the genotypes and phenotypes for Fred and Wilma Flintstone. Records results in Figure 2.

1. Identify all of the traits in which Wilma has a heterozygous genotype.

2. Is Fred lying when he tells Wilma that he thinks her hair is a gorgeous shade of red? Use the words genotype and allele in your answer.

3. Does Wilma get angry when Fred screams, “WILMAAAAA....”? Use the words genotype and allele in your answer.

4. Fred and Wilma’s daughter, Pebbles, has a headache. Wilma blames Fred because he has a family history of migraines. Does Pebbles have a migraine, or just a normal headache? Use a Punnett square to provide evidence.

5. If Fred and Wilma had a son, what is the probability of having normal vision? Use a Punnett square to provide evidence.

Name: _____________________________________________ Date: ___________________ Period: ________

Freshmen Biology- Honors

Sex-linked Traits with The Flintstones

Geneticists have succeeded in sequencing the genes on the sex chromosomes of Bedrock’s most famous couple, Fred and Wilma Flintstone. Shocking discoveries have been made - the secrets of Bedrock can now be revealed.

Directions: Analyze Figure 1 to complete Figure 2.

DominantDominant RecessiveRecessive

Allele Phenotype Allele Phenotype

O predisposed to obesity o not predisposed to obesity

N normal vision n red-green colorblind

B normal hair growth b baldness

H normal blood clotting h abnormal blood clotting (hemophilia)

D normal hearing d deafness

P pigmented eyes p non-pigmented eyes (red)

E faulty tooth enamel e normal tooth enamel

S sweat glands present s sweat glands absent

M not predisposed to migraines m predisposed to migraines

Name: _____________________________________________ Date: ___________________ Period: ________

Sex-linked Traits with The Flintstones

Geneticists have succeeded in sequencing the genes on the sex chromosomes of Bedrock’s most famous couple, Fred and Wilma Flintstone. Shocking discoveries have been made - the secrets of Bedrock can now be revealed!

Directions: Analyze Figure 1 to identify the genotypes and phenotypes for Fred and Wilma Flintstone.

FredFred WilmaWilma

Genotype Phenotype Genotype Phenotype

XOY obesity no obesity

color blind XNXn

XBY bald

XHY XHXh

XDY deaf

red eyes XPXp

XEY XeXe

XsY XSXs

migraines XMXM

Name: _____________________________________________ Date: ___________________ Period: ________

Sex-linked Traits with The Flintstones

Geneticists have succeeded in sequencing the genes on the sex chromosomes of Bedrock’s most famous couple, Fred and Wilma Flintstone. Shocking discoveries have been made - the secrets of Bedrock can now be revealed.

Directions: Analyze Figure 1 to complete Figure 2.

DominantDominant RecessiveRecessive

Allele Phenotype Allele Phenotype

O predisposed to obesity o not predisposed to obesity

N normal vision n red-green colorblind

B normal hair growth b baldness

H normal blood clotting h abnormal blood clotting (hemophilia)

D normal hearing d deafness

P pigmented eyes p non-pigmented eyes (red)

E faulty tooth enamel e normal tooth enamel

S sweat glands present s sweat glands absent

M not predisposed to migraines m predisposed to migraines

Name: _____________________________________________ Date: ___________________ Period: ________

Figure 1 Figure 2

6. Fred and Wilma’s neighbors, Barney and Betty Rubble, have a colorblind son, BamBam. Barney and Betty are confused because they both have no problem seeing color.

a. What is the genotype of BamBam?

b. Explain which parent is to blame for Bam Bam being colorblind. Use the terms genotype and allele in your answer.

d. Fred and Wilma are worried because BamBam is Pebbles’s boyfriend. Pebbles can see color. If Pebbles and BamBam have a baby what is the probability of the baby being colorblind? Use a Punnett square to provide evidence.

7. Fred and Wilma’s daughter, Pebbles, marries her first love, BamBam. BamBam is the son of Barney and Betty. Pebbles is worried that their daughter, Lexi, is going to bald like Wilma. Wilma tells Pebbles she has nothing to worry about because BamBam and his parents have normal hair.

a. Make a pedigree of this family, identify each member, and label their genotypes.

b. Is Lexi bald? Explain your answer using the terms genotype and allele.

c. Explain how it would be possible for Lexi to have a bald daughter? Use a Punnett square to provide evidence.

Name: _____________________________________________ Date: ___________________ Period: ________

Freshmen Biology- Honors