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Nervous System (part 2)reported by: tahseen raza p ahmad
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Protection of the Central Nervous System
Scalp and skin(epithelium)
Skull and vertebral column(bone)
Meninges(membranes)
Cerebrospinal fluid(watery cushion)
Blood brain barrier
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Meninges
Dura mater (tough or hard mother)
Double-layered external covering
Periosteum attached to surface of the skull
Meningeal layer outer covering of the brain andspinal cord
Folds inward in several areas
falx cerebri
Outermost layer
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Meninges
Arachnoid layer
Middle layer
Web-like
Pia mater (gentle mother)
Internal layer
Clings to the surface of the brain and spinal cord
following every fold
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Cerebrospinal Fluid (CSF)
Similar to blood plasma composition
Formed by the choroid plexus
Forms a watery cushion to protect the brain Circulated in arachnoid space, ventricles, and
central canal of the spinal cord
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Ventricles and Location of the
Cerebrospinal Fluid
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Ventricles and Location of the Cerebrospinal Fluid
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Blood Brain Barrier
Includes the least permeable capillaries of the body
Excludes many potentially harmful substances
Useless against some substances
Fats and fat soluble molecules
Respiratory gases
Alcohol
Nicotine
Anesthesia
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Spinal Cord
Extends from themedulla oblongata tothe region of T12
Below T12 is thecauda equina (horsetail) (a collection ofspinal nerves)
Enlargements occurin the cervical andlumbar regions
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Spinal Cord Anatomy
Exterior white mater conduction tracts
Figure 7.19
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Spinal Cord Anatomy
Internal gray matter - mostly cell bodies
Dorsal (posterior) horns
Anterior (ventral) horns
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Spinal Cord Anatomy
Central canal filled with cerebrospinal fluid
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Peripheral Nervous System
Nerves and ganglia (neuronal cell bodies)
outside the central nervous system
Nerve is a bundle of neuron fibers Neuron fibers are bundled by connective tissue
(endoneurium)
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Structure of a Nerve
Endoneurium
surrounds each fiber
Groups of fibers are
bound into fascicles by
perineurium
Fascicles are bound
together by epineurium
Figure 7.20
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Classification of Nerves
Mixed nerves
carrying both sensory and motor fibers
e.g. spinal nerves Afferent (sensory) nerves carry impulses
toward the CNS
Efferent (motor) nerves carry impulses awayfrom the CNS
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Distribution of Cranial Nerves
sensory for smell
sensory for vision
motor fibers to eye
muscles
motor fiber to eye
muscles
sensory for the
face; motor fibers
to chewing
muscles
motor fibers to
eye muscles
sensory for taste;
motor fibers to the
face
sensory for
balance and
hearing
sensory for taste;
motor fibers to the
pharynx
sensory and motor
fibers for pharynx,
larynx, and viscera
motor fibers to neck
and upper back
motor fibers to tongue
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Spinal Nerves
There is a pair of spinal nerves at the level of
each vertebrae for a total of 31 pairs
Spinal nerves are formed by the combinationof the ventral and dorsal roots of the spinal
cord
Spinal nerves are named for the region from
which they arise
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Anatomy of Spinal Nerves
Spinal nerves divide soonafter leaving the spinal
cord
Dorsal rami serve the
skin and muscles ofthe posterior trunk
Ventral rami forms a
complex of networks
(plexus) for the
anterior
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Spinal Nerves
Cervical
Body Areas Served
Result of Damage to
Plexus or its Nerves
Diaphragm and
muscles of shoulder
and neck
Respiratory paralysis
Brachial
Deltoid muscle of shoulder;
Triceps and extensor
muscles of the forearm
Paralysis and atrophy
of deltoid muscle
Wristdrop- inability to
extend hand at wrist
Lumbar
Lower abdomen, buttocks
anterior thighs, and skin of
antereomedial legand thigh;
Adductor muscles of medial
thigh and small hip muscles;
skin of medial thigh and hip joint
Inability to extend leg
and flex hip; loss of
cutaneous sensation
Inability to adduct
thigh
Sacral
Lower trunk and posterior
surface of thigh (and leg);
Lateral aspect of leg andfoot
Inability to extend hip
and flex knee;sciatica
Footdrop- inability to
dorsiflex foot
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Examples of Nerve Distribution
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Autonomic Nervous System
The involuntary branch of the nervous system
Consists of only motor nerves
Regulates cardiac muscles, smooth musclesand glands
Divided into two divisions
Sympathetic division
Parasympathetic division
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Differences Between Somatic and
Autonomic Nervous Systems
Nerves
Somatic one motor neuron
Autonomic preganglionic and postganglionic
nerves
Effector organs
Somatic skeletal muscle
Autonomic smooth muscle, cardiac muscle,and glands
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Differences Between Somatic and
Autonomic Nervous Systems
Nerurotransmitters
Somatic always use acetylcholine
Autominic use acetylcholine, epinephrine, or
norepinephrine
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Comparison of Somatic and Autonomic Nervous Systems
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Anatomy of the Sympathetic Division
Originates from T1 through L2
Ganglia are at the sympathetic
trunk (near the spinal cord)
Short pre-ganglionic neuron andlong postganglionic neuron
transmit impulse from CNS to the
effector
Norepinephrine and epinephrine
are neurotransmitters to the
effector organs
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Sympathetic Pathways
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Anatomy of the Parasympathetic
Division Originates from the brain stem and S1 through
S4
Terminal ganglia are at the effector organs
Always uses acetylcholine as a
neurotransmitter
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Anatomy of the Autonomic Nervous System
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Autonomic Functioning
Sympathetic fight-or-flight
Response to unusual stimulus
Takes over to increase activities
Remembered as the E division = exercise,
excitement, emergency, and embarrassment
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Autonomic Functioning
Parasympathetic housekeeping activites
Conserves energy
Maintains daily necessary body functions
Remember as the D division - digestion,
defecation, and diuresis
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Development Aspects of the Nervous System
The nervous system is formed during the firstmonth of embryonic development
Any maternal infection can have extremely harmful
effects
The hypothalamus is one of the last areas of the
brain to develop
No more neurons are formed after birth, but
growth and maturation continues for several years The brain reaches maximum weight as a young
adult
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Fetal
Maternal measles or rubella often causes
deafness
Smoking decreases the amount of oxygen may
lead possible brain damage to a smoking mother
infant
Harmful Effects on Nervous System
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Aged
Orthostatic hypotension A type of low blood pressure resulting from changes in
body position
Arteriosclerosis and high blood pressure
Decreases supply of oxygen to brain neurons which if
gradual may lead to senility, characterized by
forgetfulness, irritability, difficulty in concentrating and
thinking clearly and confusion
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Alzheimers Disease
Progressive degenerative braindisease
Mostly seen in the elderly, but may
begin in middle age Structural changes in the brain
include abnormal protein deposits
and twisted fibers within neurons
Victims experience memory loss,
irritability, confusion and ultimately,
hallucinations and death
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Parkinson's Disease
Typical on people in their
50s and 60s
Dopamine-releasingneuron degeneration
Causes overactiveness
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Huntingtons Disease
Strikes middle age which leads to massive
degeneration of the basal nuclei and later of
the cerebral cortex
Symptoms are wild, jerky and almost
continuous flapping movements
Mental deterioration occurs
Essentially symptoms of huntingtons disease is
the opposite of parkinsons disease
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Cerebrovascular Accident (CVA)
Commonly called a stroke
The result of a ruptured blood vessel
supplying a region of the brain Brain tissue supplied with oxygen from that
blood source dies
Loss of some functions or death may result
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Traumatic Brain Injuries
Concussion
Slight brain injury
No permanent brain damage
Contusion
Nervous tissue destruction occurs
Nervous tissue does not regenerate
Cerebral edema
Swelling from the inflammatory response
May compress and kill brain tissue