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    Nervous System (part 2)reported by: tahseen raza p ahmad

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    Protection of the Central Nervous System

    Scalp and skin(epithelium)

    Skull and vertebral column(bone)

    Meninges(membranes)

    Cerebrospinal fluid(watery cushion)

    Blood brain barrier

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    Meninges

    Dura mater (tough or hard mother)

    Double-layered external covering

    Periosteum attached to surface of the skull

    Meningeal layer outer covering of the brain andspinal cord

    Folds inward in several areas

    falx cerebri

    Outermost layer

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    Meninges

    Arachnoid layer

    Middle layer

    Web-like

    Pia mater (gentle mother)

    Internal layer

    Clings to the surface of the brain and spinal cord

    following every fold

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    Cerebrospinal Fluid (CSF)

    Similar to blood plasma composition

    Formed by the choroid plexus

    Forms a watery cushion to protect the brain Circulated in arachnoid space, ventricles, and

    central canal of the spinal cord

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    Ventricles and Location of the

    Cerebrospinal Fluid

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    Ventricles and Location of the Cerebrospinal Fluid

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    Blood Brain Barrier

    Includes the least permeable capillaries of the body

    Excludes many potentially harmful substances

    Useless against some substances

    Fats and fat soluble molecules

    Respiratory gases

    Alcohol

    Nicotine

    Anesthesia

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    Spinal Cord

    Extends from themedulla oblongata tothe region of T12

    Below T12 is thecauda equina (horsetail) (a collection ofspinal nerves)

    Enlargements occurin the cervical andlumbar regions

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    Spinal Cord Anatomy

    Exterior white mater conduction tracts

    Figure 7.19

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    Spinal Cord Anatomy

    Internal gray matter - mostly cell bodies

    Dorsal (posterior) horns

    Anterior (ventral) horns

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    Spinal Cord Anatomy

    Central canal filled with cerebrospinal fluid

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    Peripheral Nervous System

    Nerves and ganglia (neuronal cell bodies)

    outside the central nervous system

    Nerve is a bundle of neuron fibers Neuron fibers are bundled by connective tissue

    (endoneurium)

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    Structure of a Nerve

    Endoneurium

    surrounds each fiber

    Groups of fibers are

    bound into fascicles by

    perineurium

    Fascicles are bound

    together by epineurium

    Figure 7.20

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    Classification of Nerves

    Mixed nerves

    carrying both sensory and motor fibers

    e.g. spinal nerves Afferent (sensory) nerves carry impulses

    toward the CNS

    Efferent (motor) nerves carry impulses awayfrom the CNS

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    Distribution of Cranial Nerves

    sensory for smell

    sensory for vision

    motor fibers to eye

    muscles

    motor fiber to eye

    muscles

    sensory for the

    face; motor fibers

    to chewing

    muscles

    motor fibers to

    eye muscles

    sensory for taste;

    motor fibers to the

    face

    sensory for

    balance and

    hearing

    sensory for taste;

    motor fibers to the

    pharynx

    sensory and motor

    fibers for pharynx,

    larynx, and viscera

    motor fibers to neck

    and upper back

    motor fibers to tongue

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    Spinal Nerves

    There is a pair of spinal nerves at the level of

    each vertebrae for a total of 31 pairs

    Spinal nerves are formed by the combinationof the ventral and dorsal roots of the spinal

    cord

    Spinal nerves are named for the region from

    which they arise

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    Anatomy of Spinal Nerves

    Spinal nerves divide soonafter leaving the spinal

    cord

    Dorsal rami serve the

    skin and muscles ofthe posterior trunk

    Ventral rami forms a

    complex of networks

    (plexus) for the

    anterior

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    Spinal Nerves

    Cervical

    Body Areas Served

    Result of Damage to

    Plexus or its Nerves

    Diaphragm and

    muscles of shoulder

    and neck

    Respiratory paralysis

    Brachial

    Deltoid muscle of shoulder;

    Triceps and extensor

    muscles of the forearm

    Paralysis and atrophy

    of deltoid muscle

    Wristdrop- inability to

    extend hand at wrist

    Lumbar

    Lower abdomen, buttocks

    anterior thighs, and skin of

    antereomedial legand thigh;

    Adductor muscles of medial

    thigh and small hip muscles;

    skin of medial thigh and hip joint

    Inability to extend leg

    and flex hip; loss of

    cutaneous sensation

    Inability to adduct

    thigh

    Sacral

    Lower trunk and posterior

    surface of thigh (and leg);

    Lateral aspect of leg andfoot

    Inability to extend hip

    and flex knee;sciatica

    Footdrop- inability to

    dorsiflex foot

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    Examples of Nerve Distribution

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    Autonomic Nervous System

    The involuntary branch of the nervous system

    Consists of only motor nerves

    Regulates cardiac muscles, smooth musclesand glands

    Divided into two divisions

    Sympathetic division

    Parasympathetic division

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    Differences Between Somatic and

    Autonomic Nervous Systems

    Nerves

    Somatic one motor neuron

    Autonomic preganglionic and postganglionic

    nerves

    Effector organs

    Somatic skeletal muscle

    Autonomic smooth muscle, cardiac muscle,and glands

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    Differences Between Somatic and

    Autonomic Nervous Systems

    Nerurotransmitters

    Somatic always use acetylcholine

    Autominic use acetylcholine, epinephrine, or

    norepinephrine

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    Comparison of Somatic and Autonomic Nervous Systems

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    Anatomy of the Sympathetic Division

    Originates from T1 through L2

    Ganglia are at the sympathetic

    trunk (near the spinal cord)

    Short pre-ganglionic neuron andlong postganglionic neuron

    transmit impulse from CNS to the

    effector

    Norepinephrine and epinephrine

    are neurotransmitters to the

    effector organs

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    Sympathetic Pathways

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    Anatomy of the Parasympathetic

    Division Originates from the brain stem and S1 through

    S4

    Terminal ganglia are at the effector organs

    Always uses acetylcholine as a

    neurotransmitter

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    Anatomy of the Autonomic Nervous System

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    Autonomic Functioning

    Sympathetic fight-or-flight

    Response to unusual stimulus

    Takes over to increase activities

    Remembered as the E division = exercise,

    excitement, emergency, and embarrassment

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    Autonomic Functioning

    Parasympathetic housekeeping activites

    Conserves energy

    Maintains daily necessary body functions

    Remember as the D division - digestion,

    defecation, and diuresis

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    Development Aspects of the Nervous System

    The nervous system is formed during the firstmonth of embryonic development

    Any maternal infection can have extremely harmful

    effects

    The hypothalamus is one of the last areas of the

    brain to develop

    No more neurons are formed after birth, but

    growth and maturation continues for several years The brain reaches maximum weight as a young

    adult

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    Fetal

    Maternal measles or rubella often causes

    deafness

    Smoking decreases the amount of oxygen may

    lead possible brain damage to a smoking mother

    infant

    Harmful Effects on Nervous System

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    Aged

    Orthostatic hypotension A type of low blood pressure resulting from changes in

    body position

    Arteriosclerosis and high blood pressure

    Decreases supply of oxygen to brain neurons which if

    gradual may lead to senility, characterized by

    forgetfulness, irritability, difficulty in concentrating and

    thinking clearly and confusion

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    Alzheimers Disease

    Progressive degenerative braindisease

    Mostly seen in the elderly, but may

    begin in middle age Structural changes in the brain

    include abnormal protein deposits

    and twisted fibers within neurons

    Victims experience memory loss,

    irritability, confusion and ultimately,

    hallucinations and death

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    Parkinson's Disease

    Typical on people in their

    50s and 60s

    Dopamine-releasingneuron degeneration

    Causes overactiveness

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    Huntingtons Disease

    Strikes middle age which leads to massive

    degeneration of the basal nuclei and later of

    the cerebral cortex

    Symptoms are wild, jerky and almost

    continuous flapping movements

    Mental deterioration occurs

    Essentially symptoms of huntingtons disease is

    the opposite of parkinsons disease

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    Cerebrovascular Accident (CVA)

    Commonly called a stroke

    The result of a ruptured blood vessel

    supplying a region of the brain Brain tissue supplied with oxygen from that

    blood source dies

    Loss of some functions or death may result

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    Traumatic Brain Injuries

    Concussion

    Slight brain injury

    No permanent brain damage

    Contusion

    Nervous tissue destruction occurs

    Nervous tissue does not regenerate

    Cerebral edema

    Swelling from the inflammatory response

    May compress and kill brain tissue