New Emerging Ingredients

SSW 2008

Ingredients with Potential

• Energy• Heart Health and Bone

Health • Antioxidants• Protect against UV radiation• Cognitive Ability• Digestive Health• Lactose Intolerance• Immune Support

Health Applications for Young and Old

Age-related nutrition targets needs ofInfants, children, young and maturing adults, and aging seniors

Page 3

Application ExamplesProbiotic BC30

Natural Vitamin K2

CardioHealth

HealthyBones

Geleijnse et al., Journal of Nutrition (2004)

When consuming daily 45 μg dietary K2 you have:• 50% reduction of arterial calcification• 50% reduction of cardiovascular death• 25% reduction of all cause mortality

as compared to low intake of dietary K2!

Natural Vitamin K2

CardioHealth

HealthyBones

Prevention of arterial calcification by vitamin K2 in a rat model

• Model: 4 rats (♂)• Diet: warfarin + vitamin K1• Treatment duration: 4 weeks• Measurement: calcification by von Kossa

• Model: 4 rats (♂)• Diet: warfarin + vitamin K2• Treatment duration: 4 weeks• Measurement: calcification by von Kossa

New Grape Seed ExtractChange in blood pressure (Lu et al., 2007)

LowerBlood Pressure “

mm

Hq

p = 0.003 p < 0.05

Diastolic Systolic

8

Sardines Pork Beef Olive oil Poultry Broccoli Butter Safflower oil

Cheese

0

1

2

3

4

5

6

7

Coenzyme Q10 content in food

[Source: Kamei et al., Internat. J. Vit. Nutr. Res. 56 (1986) 57-63,

"The Distribution and Content of Ubiquinone in Foods"]

mg/

1 00g

r

• Lycopene : an antioxidant-rich carotenoid found in tomatoes and other fruits• CAP approved from FDA as natural color

• fewer allergic reactions compared with insect-derived additives• At least three artificial red dyes have adverse affects on children’s behaviors. ---

McCann et. al.; Lancet Early Online Publication 2007

• Strong clinical support for health benefits• Qualified health claim against prostate cancer• Clinical support for UV protection – beauty from within• Evidence of reduced blood pressure• Reduction of oxidative stress

The Color of Health

100% NaturalCertified Koshernon-GMOGRASVegetarian

OH

OHLutein

Lycopene

2.43

- 0.28

-0.5

0.0

0.5

1.0

1.5

2.0

2.5

3.0

Placebo PS

• PHOSPATIDYL SERINE

CognitiveFunction

Collagen BreakdownUV Protection

Collagen and elastin degenerate with age, setting the stage for the appearance of wrinkles, creases, folds, and furrows.

Illustration by Renée Gordon. Source: National Institute on Aging.

• inhibiting inflammation, as well as cellular and DNA damage caused by excess free radicals (oxidative stress)

• preferentially absorbing the harmful UV rays, including UVA!

• nourishing and strengthening collagen and elastin bonds

Nutrients Can Protect the Skin by: