Nexus Drugs Private Limited Caring for health !!

… Ready to Fillpre-formulation intermediates …

Nexus Drugs Private LimitedCompany Profile

Nexus Drugs Private Limited

Caring for health !!



Welcome to Nexus Drugs

Private LimitedYour Search for Pharma Pellets of Enteric and Sustained quality ends here. We provide complete solutions for delayed and controlled release pellets. Innovation of Pharma Pellets is ongoing process in our R&D.

SpecializationCustomized solution for your formulation Development for specialized combination Product Dosages.

Our VisionMeaningful relation with end-user of Pellets and understanding our customer needs. We continuously strive to help our customers to sharpen their competitive edge by making medicines cost effective and affordable to enhance their business value.

Our StrengthsWe have Strong Customer Base and have CRAMS with major Pharma companies. Our clients are spread around the globe.



About Us Innovation in the field of medicine and pharmaceuticals is an ongoing process. The

objective is to provide cost effective quality medicines to mitigate the sufferings of mankind.

Nexus Drugs is a fast growing organization established by a team of dedicated professionals with an experience in the pharmaceutical industry with specific reference to the development and manufacture of various modified release pellets.

The company’s forte is the customized development and manufacture of modified release pellets of various Active Pharmaceutical Ingredients (APIs) including different combination blends in “Ready-To-Fill” in capsules.

A team of qualified and experienced technical personnel, well equipped manufacturing facility and Quality Control, documentation system conforming to GMP requirements, have been instrumental in maintaining our premium position in the Pharma Industry for the manufacture of pellets.



Manufacturing

We have the best infrastructure to manufacture products of world-class quality, conforming to GMP norms.

Nexus Drugs Private Limited has adequate production capacities with specialized equipment's to meet the growing market demand.

The salient features are:

Eco-friendly surroundings.Unidirectional flow of materials.Production on campaign basis.Air handling units to meet class 100,000.Corridors at highest positive pressure.Purified water generation system to meet pharmacopeial requirements.Oil and moisture free compressed air.Capacity to manufacture 0.5 - 500 kg batch size.Annual capacity of 600 MT.



Quality

The Quality department at Nexus Drugs follows GLP recommendations and fulfills the requirement of Standards of the Regulatory authorities.

The Lab is well equipped with latest qualified test Instruments, qualified and experienced Chemists, who believe in the mission for quality not only in our products, but at each process stage.

The Quality Assurance department ensures that the products are manufactured and tested as per the requirements of GMP and ISO 9001:2008 Quality Management Systems.

Our quality policy covers:Qualified VendorsQualified Equipment'sQualified personnelWell documented training ProgramValidationsApproved sampling and testing proceduresCalibrations of monitoring and measuring equipment'sChange Control and Deviation ControlSafety, Health and Environment



Product Development

Product development activities are headed by well experienced professionals having extensive knowledge on different polymers behavior and their usage in the Drug delivery systems.

Nexus Drugs Private Limited has dedicated areas for product development and scale up studies before commercialization.

At Nexus Drugs Private Limited Product development activity is an on-going process and statistically compare the in-vitro drug release profiles against the originator products or as per market samples, where required we develop the products as per customer specifications or in-house specifications based on literature.

Commercialization takes place after successful stability studies and validations as per ICH guidelines.



InfrastructureNexus Drugs Private Limited owns a state-of-the-art infrastructural set-up. With a registered office in Hyderabad, India, the manufacturing site is located in Pashamylaram, Patancheru, Medak District, A.P., India. This production facility is amongst the largest manufacturers of omeprazole pellets in India. The production plant is constructed as per the cGMP guidelines. Further, it also meets all the regulatory requirements of US FDA,WHO GMP, EDQM etc.

The production unit is equipped with all types of manufacturing equipment's viz.:

Fluid bed coaters Pulvarisers Coating pans Sifters Tray dryers Homogenizer Double cone blender

Nexus Drugs Private Limited has established a countrywide sales and marketing network in India and abroad through professionally trained and highly motivated professionals. Furthermore, the manufacturing unit is well connected with efficient logistic network by air as well as sea to supply products to all places.



ProductsSl.No Product Name Strength Therapeutic Use

01. Omeprazole Pellets 7.50%, 8.50%, 10% & 20.0% Anti Ulcerative

02. Esomeprazole Mg Pellets 8.50%, 22.0% & 22.50 % Anti Ulcerative

03. Lansoprazole Pellets 8.50% Anti Ulcerative

04. Pantoprazole Sodium Pellets 15.0 % , & 22.50 % Anti Ulcerative

05. Itraconazole Pellets 22.0% & 35.0% Anti Fungal

06. Rabeprazole Sodium Pellets 8.50% & 11.20% Anti Ulcerative

07. Venlafaxine HCl SR Pellets 25.0% & 30.0% Central Nervous System

08. Diltiazem HCl SR Pellets 50.0 % Anti Hypertensive

09. Domperidone SR Pellets 10.0%, 30.0% & 40.0% Anti Emetic

10. Domperidone Pellets 20.0% Anti Emetic

11. Tamsulosin HCl CR Pellets 0.15% & 0.18% Benign Prostatic Hyperplasia

12. Metoprolol Succinate ER Pellets 44.0% Cardiac

13. Mebevarine HCl ER Pellets 48.0% Anti-Spasmodic

14. Ambroxol HCl SR Pellets 27.0% Respiratory

15. Itopride HCl SR Pellets 60.0% Anti-Emetic

16. Orlistat Pellets 50.0% Anti-Obesity

17. Duloxetine HCl Pellets 9.0% & 15.0% Anti-Depressant

18. Indomethacin SR Pellets 27.0% Anti-Inflammatory,Analgesic

19. Potassium Chloride SR Pellets 84.0% Anti-nutrition

20. Trihexy Phenidyl HCl SR Pellets 3.0% Anti-Parkinson

21. Blend Pellets of Rabeprazole Sodium EC Pellets + Domperidone SR Pellets 20mg + 30mg Anti-Ulcerative + Anti Emetic

22. Blended Pellets of Pantoprazole Pellets + Domperidone SR Pellets 40mg + 30mg Anti-Ulcerative + Anti Emetic

23. Propanolol HCl SR Pellets 54.0% Anti-Hypertension

24. Atorvastatin Pellets 7.82%, 10.0%, 15.63% & 20.0% Anti-Hypertension

25. Clopidogrel Bi Sulphate Pellets 50.0% Cardiovascular,Coronary Artery

26. Diclofenac Sodium SR Pellets 33.3%, 40.0% & 50.0% Anti-Inflammatory, Analgesic

27. Ketoprofen SR Pellets 70.0% Anti-Inflammatory,Analgesic



Forecasting for next 5 yearsTu

rnov

er [R

s.Cr

ores

]

Financial Year2012-13

2013-14

2014-15

2015-16

2016-17

2017-180

10

20

30

40

50

60

70

8.512

20

30

45

60



Research & Development Research & DevelopmentIntense Research and Development efforts have been a great strength of Nexus Drugs Private Limited. The company has developed ultra-modern R&D center integrated with the production facility. The center has capabilities to support constant research. The various aspects of R&D are carried out by highly skilled scientists.

To carry out research and analytic experiments, the R&D center is equipped with different types of equipment's. Some of them are:

Well equipped pilot scale equipment's Fluid Bed Coater Sifter Pulverizer Coating pan



Research & Development

Expertise of the R& D center

Process Development for existing products Modified drug release pellets with focus on 'Non-infringing Process

Development' Analytical Development Development of New Products and processes

This Ensures

Smooth technological transfers Effective and safe environmental technology Cost reduction processes Competence in providing DMF / Tech. pack along with the "Product

Development Report"



Value Proposition

Value to customer

Tackle high cost and low productivity of R&D

Leverage on intellectual capital and lower cost of research in India

A partner with process research abilities, quality driven, environmental friendly and low cost manufacturing capabilities

Contract Research

Contract research & manufacturing

*Note: In the pyramid shown above, for a particular level-all the benefits of the levels below it are also applicable.

For example: At contract research level, all benefits mentioned against lease option are also applicable

Customer requirements



Committed to Deliver …

NetworkProcess

knowledge

Human Capital

Track recordEnd-to-end

CustomervalueInfrastructure

Specific information on contract research facilities and capabilities can be furnished upon request

contact: [email protected]

THANK YOU

mailto:[email protected]

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Nexus Drugs Private Limited Caring for health !!