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Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen [email protected] Division of Behavioral and Social Research (BSR), NIA http://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/Behavio ralAndSocialResearch/ National Institute on Aging

Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen [email protected] Division of Behavioral

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Page 1: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Opportunities for Neuroeconomists at the National Institute on Aging

and through NIH-wide initiatives

Lis [email protected]

Division of Behavioral and Social Research (BSR), NIAhttp://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/BehavioralAndSocialResearch/

National Institute on Aging

Page 2: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Research Priorities at BSR/NIA

• Neuroeconomics and Decision Research *• Social Neuroscience of Aging * • Behavioral Economics• Mechanisms of Behavior Change *• Integrating genetics into behavioral models • Economic Phenotypes *• Economics of Aging (Health and Retirement) • Training Interdisciplinary Scientists – need good K and F32

applicants bridging econ/psych/neuroscience *review

National Institute on Aging

Page 3: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Understanding NIA

• Aging-relevant research is NOT just the study of older people

• Lifecourse perspective – aging as a process that unfolds; early life factors impacting trajectories of health and (subjective/economic) well-being in mid-late life

• Aging-relevant phenomena – self-regulation, motivation, delay discounting, susceptibility to fraud, social influences on decision making – through a lifecourse lens

• Changing demographic of population impacts structure of institutions, policies, and choices of individuals

National Institute on Aging

Page 4: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Resources at NIA

• Recent RFAs (inactive) reflect our ongoing interest in: – Neuroeconomics of Aging

http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-06-011.html

– Social Neuroscience of Aging http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-09-006.html

• Priority areas for research training http://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/BehavioralAndSocialResearch/PriorityAreas.htm

• Workshop Reports highlight needs for future research in these and related areas, including genetic approaches: http://www.nia.nih.gov/ResearchInformation/ExtramuralPrograms/BehavioralAndSocialResearch/CMW.htm

National Institute on Aging

Page 5: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Emerging Opportunities at NIA

National Institute on Aging

http://hrsonline.isr.umich.edu/

• Genotyping 20,000 individuals with longitudinal survey data on health and economic behaviors

• Lab-based methods (imaging) most likely to find heritable phenotypes closely linked to biology

• But only very large samples will allow genetic model estimation and replication

• Critical need for lab-survey interface around economic phenotypes

Page 6: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Emerging Opportunities at NIA

National Institute on Aging

• Network to advance Decision Neuroscience of Aging• Over five years this network grant will support scientific

meetings, intensive training workshops for researchers at all stages, and a pilot grant competition for researchers new to the field.

• Core Network Personnel: Laura Carstensen (Stanford), Samuel McClure (Stanford), Gregory Samanez Larkin (Vanderbildt), Camelia Kuhnen (Northwestern), David Laibson (Harvard)

Page 7: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

“In this economy, it’s crucial to begin everysentence with ‘in this economy.’”

Page 8: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

NIH-wide initiatives

Science of Behavior Changehttp://nihroadmap.nih.gov/behaviorchange/index.asp

OppNethttp://oppnet.nih.gov

Health Economicshttp://nihroadmap.nih.gov/healtheconomics/

National Institute on Aging

Page 9: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Science of Behavior ChangeNIH Roadmap Program

• Trans-NIH initiative to focus on approaches to improving initiation and maintenance of positive health behaviors

• Leveraging advances in emerging basic behavioral and social science domains

• NIH Directors approved Roadmap funding for developmental activities including planning meetings.

• DPCPSI, FIC, NCCAM, NCI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCR, NIDDK, NIGMS, NIMH, NINDS, NINR, OBSSR

National Institute on Aging

Page 10: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Poor Health Behaviors Kill

Schroeder et al. (2007, NEJM)

Page 11: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Behavior Change is Powerful

A 7% weight reduction and 2.5 hour per week activity increase led to a 58% reduction in the cumulative incidence of Type 2 diabetes in insulin-resistant individuals (Diabetes Prevention Program Research Group, 2002).

Page 12: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Balkanization of Behavior Change

Neuroscience

BehavioralScience

Economics

Policy

Smoking Cessation

Genetics

Medication Adherence

Increase Exercise

ModerateDrinking

FinancialPlanning

17 different ICs support research in (very specific areas of) behavior change.

Page 13: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Emergence of Transdisciplinary Science

Neuroscience

BehavioralScience

Economics

Policy

Behavior Change

Genetics

Relevant science is rapidly emerging but is not optimally focused on Behavior Change.

Behavior

GeneticsBehavioralEconomics

NeuroeconomicsCognitiv

e/Affective

Neuroscience

Page 14: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral
Page 15: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

SOBC Roadmap RFA-RM-10-002 Focused on Mechanisms of Change

Mechanisms of decision-makinge.g., risk perception, temporal discounting

Mechanisms of control and self-monitoring: e.g., executive function, interoceptive awareness, emotion regulation;

Mechanisms of social and cultural transmission of behaviors and of interpersonal transaction: e.g., contagion, mimicry, modeling, norms, peer effects, competition;

Structural mechanisms: e.g., choice architectures, defaults, environmental affordances;

Neurobiological and genetic mechanisms: e.g., related to these processes, including those associated with individual differences in biophysiologic capacity or psychological resilience/vulnerability.

National Institute on Aging

Page 16: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral
Page 17: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

OppNet: Mission and GoalsOppNet: Mission and Goals

• To strengthen basic Behavioral and Social Science Research (b-BSSR) across NIH institutes, innovating beyond existing investments

• Build a body of knowledge about the nature of behavior and social systems, focused on basic mechanisms of behavior and social processes

• Three domains:• Behavioral and Social Processes (e.g., learning, social cognition, group processes,

migration patterns)

• Biobehavioral and Biosocial Research (e.g., social, cognitive, affective and economic neurosciences)

• Methodology and measurement (e.g., data collection, modeling, research design)

Page 18: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

OppNet FY2011 FOAsRFA-AG-11-010 BASIC RESEARCH ON SELF-REGULATION (R21)2 yr; $275K total direct costs. Due Date: January 6, 2011 * Related to SOBC1) to precisely identify and operationally reconcile the basic processes and mechanisms involved in self-regulation of cognition, emotion, and behavior, and refine their measurement and theoretical conceptualizations, 2) to assess relations among various self-regulatory functions and their sub-components, and 3) to systematically characterize changes in self-regulatory functions over time, across different social and environmental contexts, and across the lifespan

CAPACITY BUILDINGRFA-CA-10-017 Due Date: December 14, 2010Scientific meetings for creating interdisciplinary research teams in emerging b-BSSR (R13)2 year; $50K/year direct

RFA-NR-11-002 Due Date: January 6, 2011 Short-term Interdisciplinary Research Education Program for New Investigators (R25) 1 year; $150K direct costs.

Page 19: Opportunities for Neuroeconomists at the National Institute on Aging and through NIH-wide initiatives Lis Nielsen nielsenli@nia.nih.gov Division of Behavioral

Research Community Input Shapes OppNet’s Directions:

OppNet Meeting: Expanding Opportunities inBasic Behavioral and Social Science

Research

Thursday and Friday, October 28-29, 2010Hyatt Regency Washington on Capitol Hill

400 New Jersey Avenue, NWWashington, DC 20001

Free registrationVisit OppNet’s website for more information: http://oppnet.nih.gov