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THAI J GASTROENTEROL 2014 Vol. 16 No. 2 May - Aug. 2015 107 Patho Corner Klaikeaw N Address for Correspondence: Naruemon Klaikeaw, M.D., Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. Case 1 A 19-year-old male presented with lower abdominal cramps, fever and mucous bloody diarrhea about four weeks. On endoscopic examination, small mucosal ulcers covered with yellowish exudates are observed. The mucosal lining between the ulcers appears normal. Biopsy results colitis with erosion and increased eosinophilic infiltration. There are clumps of large round organisms in fibrinonecrotic tissue overlying the mucosa, morpho- logically consistent with trophozoites of Amoeba (Figure 1-2). Figure 1.

Patho THAI J G 2014 Vol. 16 No. 2 Corner - · PDF fileTHAI J GASTROENTEROL 2014 Vol. 16 No. 2 May - Aug. 2015 107 Klaikeaw N Patho Corner ... Answer for patho corner Case 1 = Amoebiasis

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Page 1: Patho THAI J G 2014 Vol. 16 No. 2 Corner - · PDF fileTHAI J GASTROENTEROL 2014 Vol. 16 No. 2 May - Aug. 2015 107 Klaikeaw N Patho Corner ... Answer for patho corner Case 1 = Amoebiasis

THAI J GASTROENTEROL 2014Vol. 16 No. 2

May - Aug. 2015107

Klaikeaw NPathoCorner

Klaikeaw N

Address for Correspondence: Naruemon Klaikeaw, M.D., Department of Pathology, Faculty of Medicine, Chulalongkorn

University, Bangkok 10330, Thailand.

Case 1

A 19-year-old male presented with lower abdominal cramps, fever and mucous bloody diarrhea about four

weeks. On endoscopic examination, small mucosal ulcers covered with yellowish exudates are observed. The

mucosal lining between the ulcers appears normal. Biopsy results colitis with erosion and increased eosinophilic

infiltration. There are clumps of large round organisms in fibrinonecrotic tissue overlying the mucosa, morpho-

logically consistent with trophozoites of Amoeba (Figure 1-2).

Figure 1.

Page 2: Patho THAI J G 2014 Vol. 16 No. 2 Corner - · PDF fileTHAI J GASTROENTEROL 2014 Vol. 16 No. 2 May - Aug. 2015 107 Klaikeaw N Patho Corner ... Answer for patho corner Case 1 = Amoebiasis

THAI JGASTROENTEROL

2015108

Patho Corner

Case 2

A 20-year-old Cambodian male presented with chronic diarrhea with leg edema, HIV testing was non-reac-

tive. The stool tests were initially negative. EGD finding revealed normal. The colonoscopic findings included

scalloping appearance, mucosal cracking, and redness of mucosa. The pathology revealed inflamed colonic mu-

cosa with increased eosinophilic infiltration. A worm was identified by its characteristic stichosome, which is

muscular oesophagus surrounded by rows of secretory cells called stichocytes (Figure 3).

What is the most likely diagnosis ?

(Answer see page 109)

What is the most likely diagnosis?

(Answer see page 109)

Figure 2.

Figure 3.

Page 3: Patho THAI J G 2014 Vol. 16 No. 2 Corner - · PDF fileTHAI J GASTROENTEROL 2014 Vol. 16 No. 2 May - Aug. 2015 107 Klaikeaw N Patho Corner ... Answer for patho corner Case 1 = Amoebiasis

THAI J GASTROENTEROL 2014Vol. 16 No. 2

May - Aug. 2015109

Klaikeaw N

Case 3

A 40-year-old male presented with chronic diarrhea, HIV testing was positive. EGD finding revealed nor-

mal. The duodenal biopsies were performed and reported of inflamed small bowel mucosa with dense eosino-

philic inflammation containing adult worm, morphologically consistent with Strongyloides sp. (Figure 4).

What is the most likely diagnosis?

(Answer see page 109)

Answer for patho corner

Case 1 = Amoebiasis.

Case 2 = Capillariasis.

Case 3 = Strongyloidosis.

Figure 4.