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Pathology lab- Sheet & slide
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Slide-1: Atrophy The slide show two testicular tissues.
The left one is normal in size.
The right one is small in size and this
called atrophy
Atrophy means: decrease in the size of an
organ, due to decrease in the size or
number of the cells of that organ or tissue.
Slide-2: Atrophy The slide show atrophy in the liver.
The central vein looks atrophic, and the
cells are small in the size, and there are
gaps (here cells are lost) between them.
Also we have a brown pigment (yellow-
brown, lipobrown, lipofuscin), this
pigment start to accumulate in cells such
as hepatocytes, kupffer cells, when these
cells start to die or atrophy.
Slide-3: Hypertrophy The slide show hypertrophy in the left
ventricle.
At some conditions when the tissue get
over-load, over-function, like in
hypertension, tissue will start to
accommodate.
Heart muscle cells can’t divide so they
will start to get hypertrophy (increase in
size).
Slide-4: Hyperplasia The normal size of prostatic gland is 3-4
cm in the diameter.
The slide shows large prostate which is
composed off nodules.
Nodules are not normally found, and they are
part of prostatic hyperplasia.
Slide-5: Hyperplasia The slide show a histological section of
the same hyperplastic prostate we have
talked about.
The epithelial lining is more stratified
and has more layers.
Also stroma starts to proliferate.
Pathology lab- Sheet & slide
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Slide-6: Metaplasia: The slide shows a tissue that supposed to
be an esophageal tissue.
Esophageal tissue: the normal lining of
esophagus, which is non-keratinized, stratified
squamous epithelium.
In the left side, we have columnar
epithelium lining mucosa -like which is
found in the stomach-, and this called
esophageal metaplasia.
In esophagus, in gastroesophageal reflux
disease, acid that is retained from the
stomach upward will cause chronic
irritation.
So mucosa accommodate to change it is
type, and become columnar, as gastric
mucosa.
And esophagus tissue will change from
non-keratinized to columnar epithelium.
Slide-7: Fatty change Intracellular accumulation may be
pathological or physiological.
The slide shows a liver with fatty
change.
Fatty droplets are accumulated in the
hepatocytes and kupffer cells
(macrophages of the liver).
Slide-8: Prussian blue reaction This reaction used in the demonstrating
of iron accumulated in the hepatocytes.
The cells will appear blue (blue
accumulation within hepatocytes and
kupffer cells of the liver, due to specific
condition that lead to increase in the iron
of the liver such as hemochromatosis,
hemosedrosis,…etc.
From the slide “A Prussian blue
reaction is seen in this iron stain of the
liver to demonstrate large amounts of
hemosiderin that are present within the
cytoplasm of the hepatocytes and
Kupffer cells.
Pathology lab- Sheet & slide
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Slide-9: Anthracosis The slide shows lung tissue with
anthracosis.
There are black coal pigments within
macrophages known as anthracotic
pigment, due to history of smoking; also
can be due to breathing only.
Slide-10: Acute inflammation As a sign of acute inflammation in the
peripheral blood there will be
“segmented neutrophils” which is
accumulated such as PMN’s.
PMN’s may have 3 or 5 loops.
Slide-11: Chronic inflammation As a sign of chronic inflammation
some inflammatory cells will go to the
tissue, such as plasma cells,
lymphocytes, and histiocytes (activated
macrophages).
Slide-12: Abscess formation In some cases of acute inflammation,
where it becomes aggravated, some
accumulations might take place theses
called abscess.
If the abscesses undergo liquefactive
necrosis the end result will be cavities
in the tissue.
The slide shows lung tissue, started with
pneumonia, the abscess formation, then
liqufactive necrosis, and end with
cavities.
Slide-13: Effusion Effusion: accumulation of fluid within
the body cavity.
Effusion might be exudate (rich in
protein) or transudate (not rich in
protein).
The slide shows a clear yellow fluid
within the pleural cavity, this fluid
usually 500 ml maximum, but here
there is a large amount of it, and this is
called “serous effusion”.
Pathology lab- Sheet & slide
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Now take a break and enjoy
reading this page.
Humanist announcement:
بهدف ذلكو ,أطلقت مجموعة أطباء و أكثر حملة من عيوني حياة
8عدد من القرنيات خالل تحطيم رقم قياسي جديد في جمع أكبر
0220-20-02سيكون يوم حضور الحكم من غينيس هو .ساعات
. 9- 2الساعة من السيتي مولفي
الرقم القياسي السابق سجل في الواليات المتحدة األمريكية تقريبا
قرنية ليس فقط لدخول 0444لجمع بمساعدتكم سنسعى ,2666
رنية و ال ق 054جينيس بل ألن األردن بحاجة سنويا إلى ما يقارب
0644لخارج تقريبا و تكلفة استيرادها من ا,054إال يتوفر منها
دينار أردني .
عملمن يود التبرع بقرنيته بعد عمر طويل ان شاء هللا التواصل
.أو مع إبراهيم الشنطي ء شاهيناو مع شيمغول االزاسيل
:بعض األسئلة التي تكررت
وثيقة التبرع غير الزامية في حال معارضة األهل و هم غير .0
.ةملزمون بتطبيقها قانوني
من الناحية الشرعية لدينا فتوى شرعية من دائرة االفتاء بجواز .6
و سيشاركنا بالحملة كل , ر و هو من باب الصدقة الجاريةهذا االم
. كتور محمد نوح قضاة و الشيخ محمد العريفيمن الد
أخذ القرنية ال يؤدي إلى أي تشويه لدى المتبرع.3
.ساهم في أن يرى غيرك النور
Find the ten differences:
Maze game :P :
Sudoku:
Special quote:
“A Friend in need is a friend indeed”
Pathology lab- Sheet & slide
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Slide-14:Serosanguinous
effusion The slide shows right and left lung.
There is a bloody red effusion.
This demonstrates an accumulation of
RBC’S + a transudate, and this is named
Serosanguinous effusion.
Slide-15: Fibrinous exudate When the effusion start to
accumulate, and fibers start to
approach, the viscera and right
peritonea of the lung start to organize,
and give fibrous tissue.
This is called fibrinous exudate,
because it is rich in protein.
Slide-16: Ulcer Means discontinuity of certain
tissue.(for the picture refer to the soft
copy of the slides)
Slide-17: Gangrene The leg looks: 1.brown in color.
2. has certain ulcer.
and this is called gangrene.
When tissue has decreased blood
supply in some conditions, like
diabetes, the tissue will start to have
coagulative necrosis, if the bacterial
infection is superimposed, this will
result in liqufactive necrosis, at the
end gangrene will result, and this is
called wet gangrene.
Slide-18: Granulation tissue When the tissue is injured, the body
will start to form new tissue, with
proliferation of new small blood
vessels, fibrous tissue, and infiltrated
inflammatory cells.
The slide shows multiple blood
vessels, fibroblast in the stroma, and
some infiltrated inflammatory cells.
Pathology lab- Sheet & slide
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Slide-19: Scar formation One of the healing mechanisms.
The slide shows lung with alveolar
spaces, and normal alveolar lining.( At
the bottom of the picture)
(At the top of the picture), there is
some eosinophilic bodies, and this is
called scares.
Scar formation start due to
accumulation of collagen strands,
which will start to organize, and give
scar as healing process.
Slide-20: Pulmonary
granulomas. The expanded area indicates the
pulmonary granulomas
The expanded area is due to:
1. Multinucleated giant cells
(Histiocytes).
2. A band of fibroblast.
3. Infiltrated inflammatory cells
such as plasma cells, and
lymphocytes.
It is not caseating granuloma.
Slide-21: Caseating granuloma The central is a pink acelluar area
composed of a shadow of cells.
The central is surrounded by :
1. Plasma cells
2. Lymphocytes
3. Infiltrated inflammatory cells.
Done by:
Ibrahim Shanti
Ibrahim Sabri