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PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

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Page 1: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

PATRICIA RONAN & DOMINIC HARBINSON

Acupuncture and SchizophreniaChoices for collecting evidence:

Limitations and Significance

Page 2: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Research Context

Audience & Funders: Western Medical CAM – BAcC & Medical Harmony Charities – Sir Charles Jessell Fund University - CCCU limited understanding of acupuncture many sceptics bio-pharmacological competition economics of medical research

Page 3: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

The problem with acupuncture ....

PhilosophyTerminologyNo standard approach (5 element / stems &

branches / TCM etc...)No standard treatment (even within individual

approaches)Problems regarding ShamTherapist effect

Page 4: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

The problem with schizophrenia

• Difficult to define• Difficult to diagnose• Arguments about validity of the condition• Complex condition• Confounded by antipsychotic medicine and

other associated treatments• Lifestyle factors• ?unpredictable client group

Page 5: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Challenge 1

How to do this research? RCT Experimental study Delphi Feasibility study Case study

Best Research approach – who’s right?

Page 6: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Challenge 2

Recruitment

Psychotic vs schizophrenic?Forensic vs acute vs primary careAllies and sceptics Busyness of teamsGeographical area

Page 7: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Challenge 3

Time and Money Acupuncturists not employed by NHS or university Too long and bias if PR trained Acceptability of such a study to NHS & NHS funders Time to write a bid vs PhD timescale Experience and credibility of researchers and

academic institution Allies in all camps

Page 8: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Challenge 4

The ethics process We loved it! Not! Guidance 60 pages long NHS process changed again halfway through University process as well (and different) Peer review and academic arguments about best

research approach

Page 9: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Challenge 5

Administration Research Passport – great, but... Interpretation of new rules Co-ordination of honorary contracts / letters of access Signatures Local rules, paperwork and access IT training

Page 10: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Challenge 6

Recruitment in real life Getting the teams on board Orientation & room bookings Clinicians understanding/portrayal of the study? Patient reaction to information What worked best? Co-ordination of first information sessions, consent,

interviews and timetable

Page 11: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

And suddenly......

We had 10 participants and a schedule for interviews that meant the acupuncture could begin on January 18th 2010.

Page 12: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

But then.......

It snowed ........

Page 13: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance
Page 15: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Data Collection

Case Study Approach PANSS QoL SQLS PSQI History (case notes, medication, diet) STRICTA Observational data

Page 16: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Themes

• Sleep – Time in bed • Energy• Weight• Diet• Addictions and cravings• Exercise• Isolation• Sex• Hallucinations, Anxiety & Paranoia• Side Effects

Page 17: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Changes so far...

• Sleep & Energy: improvements in most• Weight: improvements for 2 or 3• Diet: improvements for 2 or 3• Exercise: improvements for most• Socialisation & work: improvements for most•  Sex: improvements for most• Use of Addictive substances: decreased use for most• Muscular Tension : decreasing• Anxiety: decreasing• Paranoia : decreasing• Hallucinations : decreasing• Side-effects: decreasing

Page 18: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Initial Reflections and Quandaries

Differences between what participants report to acupuncturists and to researcher

What to treat: Physical illness / symptom / what participant wants treated?

Getting up, getting there: how to deal with motivation and excessive sleep

Addictions, motivation and schizophrenia

Page 19: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Reflections on Methods

STRICTA: Helpful, but differences in acupuncture approach / philosophy?

Triangulation : helpfulness of variety of collection methods – acupuncturists, case notes, interviews, carers

Researcher / Nurse / Person?Recruitment: culture & understanding of

research and acupuncture

Page 20: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Reflections on Methods

PANSS – helpful, but problems in validationPANSS – helpful before QoL InterviewQoL – good & quick method of capturing

picture, but: ? Christmas ? Inclusion of sex, weight & excretion ? Consistency of information given – e.g. PSQI vs QoL,

Int 1 vs Int 2, embarrassment

Page 21: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Diagnosis

Syndrome D W

Liver Depression Qi Stagnation 6 1Heart Fire 1Heart-Kidney not Harmonised 2Stomach Yin & Spleen Qi Deficiency 1Spleen Qi Deficiency generating Dampness 2 1Kidney Deficiency / Kidney Qi not Firm 1 1Phlegm-Fire Harassing the Mind 4Liver & Heart Blood Deficiency 2 1Liver Yang Rising 2Liver & Kidney Yin Deficiency 2Kidney Failing to Receive Qi 1Lung & Kidney Deficiency leading to Phlegm in the Lung 1Local Stagnation of Qi & Blood 3 1

Page 22: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Acupuncture Treatment

• Points used – same as used everywhere else!• Du 20; Liv 3; GB 34; LI 4; GB 21; SJ 5; P 8; Sp 6;

St 8-36-40; Ren 4-6-12-17; Kid 3-6-7-10 back shu/outer Bl points

• Ear acupuncture • Ashi points – vs pain/tension • Other Treatments:• Cupping / TDP lamp / relaxation tapes / ear seeds

/ herbal teas• Advice: diet, exercise, mental patterns, dating,

alcohol, salt pipe

Page 23: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

The Up & Down Sides

Ups Treating twice a week Very good attendance Actually managed to

effect some positive change!

Really great health centre

Downs Moving rooms each day Travel Stricta NHS Budgets being cut

Page 24: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Surprise!

Young age group

Weak pulses

Good attendance

Gains in main complaints are v difficult to make & hold because the problems are so deep-rooted

Will it stand the test of time?

Page 25: PATRICIA RONAN & DOMINIC HARBINSON Acupuncture and Schizophrenia Choices for collecting evidence: Limitations and Significance

Patricia Ronan Dominic Harbinson

Social Work, Community & Mental Health

Canterbury Christ Church University

CanterburyKentCT1 [email protected]

07903 054699

21 Hospital LaneCanterburyKentCT1 2PE

[email protected]. canterburyacupuncture

.co.uk

07903 363912

Contact Details