PG Degree Course in M.Sc. (Chemistry) Programme Code : PCHsrnmcollege.ac.in/event_img/84666c22dfc097ed3830efafb7dc38cf6… · nomenclature - pro-R and pro-S and Re and Si faces -

SRI S. RAMASAMY NAIDU MEMORIAL COLLEGE, SATTUR - 626 203

(An Autonomous, Co-educational and Linguistic Minority Institution Affiliated to Madurai Kamaraj University)

(Re-Accredited with Grade ‘A’ by NAAC)

PG Degree Course

in

M.Sc. (Chemistry)

Programme Code : PCH

OBE - Regulations 2020

(For I and II Semester)

Outcome Based Education

Under

Choice Based Credit System (CBCS)

(Those who joined in 2020-2021 and after)

SRNMC REGULATIONS (OBE) 2020 SYLLABUS

Department of Chemistry (Syllabus for those who joined in 2020-2021 and after) 1

Vision

To provide cognitive skills in chemical science and craft them with humanitarianism.

Mission

To afford students with a deep indulgence of chemical knowledge and a range of transferable skills.

To instil them about their responsibilities to tackle the societal challenges.

Programme Educational Objectives (PEOs)

PEO1 Successful profession in chemical sciences/ Industries/ public sectors /entrepreneurship.

PEO2 Leadership qualities with social consciousness and professional ethics

Programme Outcomes (POs)

PO1 Assimilate advanced knowledge in the core subject with relevant practical inputs.

PO2 Incorporate a more significant and superior knowledge in the major areas of chemistry –

Organic chemistry, Inorganic Chemistry and Physical Chemistry.

PO3 Apply reasoning informed by the contextual knowledge to assess societal, health, safety,

legal and cultural issues and the consequent responsibilities relevant to the professional practice.

PO4 Function effectively as an individual, and as a member or leader in diverse teams, and in

multidisciplinary settings.

PO5 Comprehend and write effective reports, design documentation and make effective presentations.

PO6 Demonstrate attitude, skills and knowledge of a well - groomed personality at work and social

environment.

PO7 Broaden professional foundation through activities such as teaching (seminars), internships, industrial

visits and projects.

PO8 Build up problem solving, decision-making and communication skills with the educated community.

Programme Specific Outcomes (PSOs)

Upon completion of the programme,

PSO1 The students are enabled to integrate the chemistry of many natural products, organic compounds,

inorganic compounds, intermediate compounds, drugs and biologically important compounds.

PSO2 The students will be proficient in the advanced level understanding of all the areas of chemistry, for

facing competitive exams like NET, SET, GATE, etc.,

PSO3 The students will be able to clearly articulate scientific information in oral, written and

electronic formats.

PSO4 The students will be skilled in examining specific phenomena theoretically and /or experimentally,

and the graduate is able to contribute to the generation of new scientific insights or to the innovation

of new applications of chemical research.

PSO5 The students will appreciate the central role of chemistry in our society and use this as a basis for

ethical behavior in issues facing chemistry including an understanding of safe handling of

chemicals, environmental issues and key issues of our society in energy, health and medicine.



Objectives

To enable the students

1. To gain knowledge on the basic and advanced level aspects in the different disciplines of

chemistry.

2. To get an exposure to the basics in nano chemistry and biochemistry.

3. To gain knowledge on the basic and advanced level experimental techniques.

4. To get an exposure on some current trends in chemistry.

Eligibility for Admission

B.Sc. degree with chemistry as the core subject and physics as one of the allied subjects; the other

allied subject may be any one of the following: Mathematics, Botany and Zoology.

Duration of the Course

The duration of the course shall be two academic years comprising four semesters with two

semesters in each academic year.

Courses of Study

1. Core subjects

2. Major elective subjects

Extra Credits Course:

1. This course is optional for students. If he/she selects this course and if he/she passes the course, then

2 extra credits will be added in his/her total credit to the degree, even otherwise, it won’t affect the

completion of degree.

2. The course is common to all UG Programmes.

3. The title of this course is “Model Paper for Competitive Examinations”

4. Examination for this course will be held at the end of the 6th semester examinations.

5. There is no internal examination and only external examination for this course.

6. Maximum marks for this course is 100.

7. There is no contact hours for this paper.

Scheme of Examination:

100 questions (multiple choice) - one mark for each.

Passing minimum is 50 marks.

Duration of the Examination is two hours.

Pattern of the Question Paper

Theory

Part A

Ten questions (Multiple choice) 10 x 1 = 10 marks

Two questions from each Unit

Part B

Five questions (either or type) 5 x 7 = 35 marks

One question from each Unit

Part C

Three questions (out of five) 3 x 10= 30 marks

One question from each unit

---------------

Total 75 Marks

---------------



Evaluation

The performance of the student is evaluated in terms of percentage of marks with a provision for

conversion to grade points. Evaluation for each course shall be done by a continuous internal assessment by

the concerned course teacher as well as by an end semester examination which will be written type

examination of 3 hours duration and will be consolidated at the end of the course. The ratio of marks to be

allotted to continuous internal assessment and to end semester examination is 25:75 (i.e. Internal 25 Marks

and external 75 Marks)

The components of continuous internal assessment are

Average of two tests 15 Marks

Seminar/Group Discussion 5 Marks

Assignment 5 Marks

Total 25 Marks

Passing Minimum

A) Theory

1. 50% of the aggregate (External+ Internal)

2. No separate passing minimum for Internal

3. 34 Marks out of 75 is the passing minimum for the External.

B) Practical

1. 50% of the aggregate (External+ Internal)

2. No separate passing minimum for Internal

3. 27 Marks out of 60 is the passing minimum for the External.

C) Project

1. 50% of the aggregate (Project Evaluation + Viva Voce+ Internal)

2. No separate passing minimum for internal.

3. 27 marks out of 60 is the passing minimum for the External.



M.Sc. (Chemistry) Course Pattern (Table - 1)

Semester Study

Components I II III IV V

Total

Hours

Total

Credits

No. of

Courses

Total

Marks

I

Core 5(5) 5(5) 5(4) - -

30 22 5 500 Elective - - - 5(4) -

Practical - - - - 10(4)

II

Core 5(5) 5(4) 5(5) - -

30 22 5 500 Elective - - - 5(4) -

Practical - - - - 10(4)

III

Core 5(5) 5(5) 5(5) - -

30 23 5 500 Elective - - - 5(4) -

Practical - - - - 10(4)

IV

Core 5(5) 5(5) 5(5) - -

30 23 5 500 Elective - - - 5(4) -

Project - - - - 10(4)

Extra Credit

Course

3



Course Structure - M.Sc. (Chemistry)

Sem

este

r

Core /

Elective /

Skill Based

Title of the Course Course Code

Contact Hrs.

Cre

dit

s

Ex

am

Hrs

.

Marks

L T P Int. Ext. Total

I

Core-I

Organic Chemistry - I

Stereochemistry and reaction

mechanism-I

P20CHC11 5 - - 5 3 25 75 100

Core-II

Inorganic Chemistry – I

(Inorganic Spectroscopy,

Coordination Chemistry

and Nano Chemistry)

P20CHC12 5 - - 5 3 25 75 100

Core-III

Physical Chemistry-I

Thermodynamics and

electrochemistry

P20CHC13 5 - - 4 3 25 75 100

Elective-I a) Environmental Chemistry

b) Bio Chemistry

P20CHE11

P20CHE12 5 - - 4 3 25 75 100

Core-IV (P) Practical-I Inorganic Chemistry P20CHC1P1 - - 10 4 6 40 60 100

Total 20 - 10 22 - - - 500

II

Core-V

Organic Chemistry-II Natural

products, conformational analysis

and reaction mechanism-II

P20CHC21 5 - - 5 3 25 75 100

Core-VI Inorganic Chemistry-II

Bioorganic and Nuclear chemistry P20CHC22 5 - - 4 3 25 75 100

Core-VII

Physical Chemistry-II

Quantum, catalysis and molecular

spectroscopy-I

P20CHC23 5 - - 5 3 25 75 100

Elective-II a) Analytical chemistry

b) Applied chemistry

P20CHE21

P20CHE22 5 - - 4 3 25 75 100

Core-VIII (P) Practical-II Organic Chemistry P20CHC2P1 - - 10 4 3 40 60 100

Total 20 - 10 22 - - - 500



Core Course I - Organic Chemistry - I (Stereochemistry and Reaction Mechanism-I)

Programme Programme Code Semester Course Code Hours Credits

M.Sc. Chemistry PCH I P20CHC11 5 5

Course Learning Outcomes:

At the end of the course, students will be able to

CLO1 Understand the relationship between structure of the compound and its reactivity and various

types of Aromaticity and Applications of Huckel‟s theory.

CLO2 Predict the stability of compounds and criteria for aromaticity in non- benzenoid molecules and

other advanced polycyclic aromatics.

CLO3 Obtain knowledge about stereochemistry, Aromaticity and different types of Reactive

intermediates.

CLO4 Categorize different types of Reactive intermediates and its properties and Stereo specfic and

stereo selective reaction.

CLO5 Sketch and analyze the stereochemistry of various organic compounds.

UNIT-I ELECTRON DISPLACEMENT AND STRUCTURE-REACTIVITY CORRELATION

Inductive and field effects – bond distances - bond energies – delocalised bonds - cross conjugation–

rules of resonance effect -steric inhibition of resonance–hyper conjugation - hydrogen bonding–addition

compound–EDA complexes -inclusion compounds. Quantitative treatment of the effect of structure on

reactivity – The Hammett relationship - significance of reaction and substituent constants - application of

the Hammett equation in reaction mechanism – significance of sigma and rho - limitations and deviation -

Taft equation.

UNIT- II STEREOCHEMISTRY –I

Symmetry elements - Concept of chirality, necessary and sufficient conditions for chirality–

Relationship between substrate symmetry and chirality-Projection formulae– Wedge, Fischer, Sawhorse and

Newmann - Optical isomerism due to centre of chirality - Molecules with one stereogenic centre (chiral

centre) and molecules with more than one chiral centre – Chirality in molecules with non-carbon

stereocenters (N, S and P) - calculation of number of stereoisomers - properties of enantiomers and

diastereoisomers – erythro and threo nomenclature – Cahn- Ingold - Prelog system of designation of

configuration . Methods of determining configuration – Separation of enantiomeric mixtures (kinetic,

enzymatic, chromatographic resolutions) – Resolution of racemic modification.

Geometrical isomerism: E-Z nomenclature-determination of configuration of geometrical isomers

using physical and chemical methods–stereoisomerism in monocyclic compounds (upto six membered ring).

UNIT -III STEREOCHEMISTRY II

Prochirality and prosteroisomerism, enantiotopic and diastereotopic ligands and faces and their

nomenclature - pro-R and pro-S and Re and Si faces - Stereospecfic and stereoselective reactions -

Asymmetric synthesis; Cram and Prelog rule - Optical isomerism due to axial chirality - biphenyl, Allenes

and spiranes - Molecules with planar chirality – paracyclophanes, trans-cyclooctene and ansa compounds.

Chiral catalysts and reagents.



UNIT –IV AROMATIC CHARACTER

Aromatic character in benzene, six membered rings, five, seven and eight membered rings – other

systems with aromatic sextets–Huckel’s rule–Craigs rule–concept of homoaromaticity and antiaromaticity-

systems with 2,4,8 and 10 electrons – systems with more than 10 electrons – Mobius aromaticity – Alternant

and nonalternant hydrocarbons-Chemistry of cyclopentadienyl anion– Fulvene, Azulene, Tropolones,

Sydnones and Annulenes. Novel ring system: Nomenclature of bicyclic and tricyclic systems- chemistry of

adamantane, diamantane (congressane), cubane and catenanes - Heteraromatic molecules- synthesis and

reactivity of quinoline, isoquinoline, and skraup synthesis – Fischer indole synthesis.

UNIT–V INTRODUCTION TO REACTION MECHANISM

Reaction intermediates–free radicals, carbenes, nitrenes, carbanions, carbocations formation and

stability of reaction intermediates–methods of determination of reaction mechanism- Thermodynamic and

kinetic requirements of a reaction -kinetic and thermodynamic control of chemical reaction – – Intermediate

versus transition state – Analysis of product and intermediate - Isotopic labeling – Stereochemical studies –

Crossover experiments – Kinetic methods– Isotopic and substituent effects - Kinetic and non kinetic methods

for determining organic reaction mechanism–principle of microscopic reversibility – Hammond postulate-

Partial rate factors - ortho/para ratio .

Text Books:

1. G.R. Chatwal (2012), Reaction mechanism and reagents in organic chemistry, 5th Edition, Himalaya

Publishing House.

2. D.Nasipuri (2011), Stereochemistry of Organic compounds, Principles and Application, 3rd Edition,

Wiley eastern Ltd., New Delhi.

3. P.S. Kalsi (2005), Stereochemistry conformation and Mechanism, 5th Edition,

New Age International Publishers.

4. I.L. Finar (2012), Organic chemistry Vol-II, 5th Edition, ELBS Longmann.

5. V.K Ahluwalia (2007), Organic reaction mechanism, 3rd Edition, Narosa publishing House, New Delhi.

Reference Books:

1. Peter Sykes (1988), Guide book to Mechanism in Organic chemistry, Reprint, Orient longmann Ltd.,

New Delhi.

2. R.T.Morrison and R.N. Boyd (2012), Organic chemistry, 7th Edition, Prentice, Hall.

3. E.S. Gould (2006), Mechanism and Structure of Organic Chemistry, 2nd Edition, Holt, Rinehart and

Winston Inc, New York.

4. E.l.Eliel (Reprint 2011), Stereo chemistry of Organic compounds, Mc Graw Hill

5. Jerry March (2013), Advanced Organic Chemistry, 6th Edition, John Wiley and Sons., New York.



Core Course II - Inorganic Chemistry – I

(Inorganic Spectroscopy, Coordination Chemistry and Nano Chemistry)





CLO1 Identify the principles, structure and reactivity of selected coordination complexes.

CLO2 Interpret their electronic spectra and magnetic properties.

CLO3 Understand the key features of coordination compounds, including, the variety of structures,

coordination numbers, ligands, chelates, bonding, and stability of complexes .

CLO4 Use Crystal Field Theory to understand the magnetic properties (and in simple terms the color) of

coordination compounds.

CLO5 Recognize the different types of nanomaterials, properties, and applications of advanced

functional nanomaterials.

UNIT -I CO-ORDINATION CHEMISTRY-I

Basics of co-ordination compounds-IUPAC nomenclature of co-ordination compounds–isomerism

in co-ordination compounds–types of ligand monodentate, ambidentate and macrocyclic ligands–chelate

and its applications–detection of complex formation in solution–stepwise stability constant-overall stability

constant-factors affecting stability constant in solution–determination of stability constant by

spectrophotometric, polorographic and potentiometric and Job’s method.

UNIT-II CO-ORDINATION CHEMISTRY-II

Theories of bonding: VB theory and CFT theory – splitting of d-orbitals in Oh, Td, square planar

and tetragonal distortion –Jahn-Teller distortions – CFSE calculation in terms of Dq – factors affecting

crystal field splitting energy– spectrochemical series – applications of CFSE – MOT diagram of octahedral,

Td and square planar complexes – effect of p-donor and p-acceptor ligands – magnetic properties of

transition metal complexes – calculation of spin-only magnetic moments –orbital contribution to the

magnetic moment – spin orbit coupling.

UNIT- III ELECTRONIC SPECTRA OF TRANSITION METAL COMPLEXES

Types of electronic transition- d-d transition- charge transfer transition.- L-S coupling- Microstates

–Term symbol-selection rules – mechanism of breakdown of selection rules- bandwidths and shapes- Jahn

Teller effect –Orgel diagram --Tanabo-sugano diagram for various dn configuration-Racah parameter-

evaluation of 10Dq -Nephelauxetic ratio( ß) for Co(III)and Cr(III) complexes.

UNIT- IV APPLICATION OF SPECTROSCOPY TO THE STUDY OF INORGANIC

COMPOUNDS

Mossbauer spectroscopy

Mossbauer effect- resonance absorption-Doppler effect- Doppler velocity –isomer shift-magnetic

hyperfine splitting-application of Mossbauer spectroscopy in the study of iron and tin complexes. NMR

Spectroscopy: Multinuclear NMR- 31P, 19F and15N NMR – introduction –application in structural problem-

(ClF3 , SF4 , PF5, BrF5, P4S3, PF3(NH2)) evaluation of rate constants –NMR of fluxional molecules –NMR of

paramagnetic molecules- contact shifts and shift reagents.



UNIT-V NANOCHEMISTRY

Basic idea of nanoscience–dimensional in nano structures-,0D,1D,2D and 3D ,synthesis of nano

materials -chemical method, sol gel , chemical vapour deposition- ball milling-plasma arcing-

electrodeposition- thermolysis. Carbon nanotubes: Types of carbon nano tubes- structure, properties and

applications of single walled carbon nano tubes. Nano Shells: Introduction-types- properties and

applications in Ion selective film, gold nanoshell for blood Immunoassay - cancer detection and therapy.

Nano polymers: Conductive polymer and block copolymer. Applications of nano materials- Insulation

material-machine tools-high power magnets-motor vehicle and aircrafts.

Text books:

1. James E. Huheey, Ellen A. Keitler and Richard L. Keitler (1993), Inorganic Chemistry-principles of

structure and reactivity, 4th Edition, Harper Collins College Publishers.

2. J. D Lee (1996), Concise inorganic chemistry, 5th Edition, Black well science Ltd.

3. B.K Sharma (2005), Spectroscopy, 17th Edition, Geol Publishing House, Meerut.

4. Asim k Das & mahuda Das (2014), Fundamental concepts of inorganic chemistry, 1st Edition,

CBS Publishers & Distributors pvt Ltd, New Delhi.

5. Mick Wilson (2008), Nanotechnology, 1st Edition, Overseas Press India Private Limited, New Delhi.

Reference Books:

1. K.F. Purcell and J.C. Koltz (1980), An Introduction to Inorganic Chemistry, 1st Edition, W.B. Saunders

Company, Philadelpha.

2. Alan G Sharpe (Reprint 2005), Inorganic Chemistry., 3rd Edition, Pearson education Ltd, Singapore.

3. Charles P. Poolee Jr. and Franck Owens (2006), Introduction to Nanotechnology, 1st Edition,

John-Wiley and Sons., New York.

4. R.D Madan (Reprinted 2002), Modern Inorganic Chemistry, S. Chand &company Ltd.

5. F. A Cotton and Wilkinson (1998), Advanced Inorganic chemistry, 4th Edition, John Wiley and sons.,

New York.



Core Course III - Physical Chemistry – I

Thermodynamics and Electrochemistry





CLO1 Validate the significance of molecular partition function and thermodynamics law.

CLO2 Acquire the knowledge of the concept of various types of equilibria.

CLO3 Interpret the wave function and apply operators to obtain an information about a particles physical

properties such as position, momentum and energy.

CLO4 Impart the knowledge on an essential aspects of electrochemical cells, EMF and application of

EMF measurement.

CLO5 Apply electrochemistry concept to create the structure of electrical double layer and analyse the

significance.

UNIT-I CHEMICAL THERMODYNAMICS

Second law of thermodynamics, concept of entropy. Gibbs-Helmholtz equation, Maxwell relations

and thermodynamic equation of state. Partial molar quantities – Chemical potential, its variation with

temperature and pressure, Gibbs Duhem equation. Experimental determinations of fugacity of real gases

(Graphical, from state equation, approximate and generalized methods).Third law of thermodynamics –

Nernst theorem, absolute entropies, determinations of absolute entropies, exception to third law and

unattainability of absolute zero.

UNIT-II CHEMICAL AND PHASE EQUILIBRIA

Spontaneous reactions, free energy of a spontaneous reaction, role of temperature, standard free

energy change of a reaction. Thermodynamic derivation for the law of chemical equilibrium, Van’t Hoff’s

reaction isotherm. Temperature dependence of equilibrium constant, Integrated form of the Van’t Hoff

equation. Relation between Kp and Kc. De Donder’s concept of degree of advancement of a reaction.

Gibbs phase rule - its thermodynamic derivation. Application of phase rule to three component

systems - systems composed of two solids and a liquid (crystallization of pure components only, hydrate and

double salt formation ). Formation of one pair, two pairs and three pairs of partially miscible liquids.

UNIT–III BASIC PRINCIPLES OF QUANTUM MECHANICS

Failure of classical mechanics-introduction of quantum mechanics- Planck’s explanation about black- body

radiation, de-Broglie’s concept of matter waves ( Experimental technique and verification), Compton effect,

Heisenberg’s uncertainty principle, Postulates of quantum mechanics, Operators (addition, subtraction,

multiplication, commutator, Hermitian, Hamiltonian and linear operators), Rules for setting up the following

quantum mechanical operators - position, momentum, kinetic energy, potential energy, total energy, angular

momentum, raising and lowering of spin angular momentum. Problems on evaluation of commutators and

find expressions of some operators. Simple problems based on to find out the eigen values and eigen

functions. Orthogonality and normalization of wave functions. Significance of Ψ and Ψ2.



UNIT-IV ELECTROCHEMISTRY - I

Theory of electrolytic conductance – inter ionic attraction, ionic atmosphere, thickness of ionic

atmosphere. Debye Huckel - Onsager conductance equation – its derivation and experimental verification,

deviations and modifications-Debye Falkenhagen and Wein effects.

Mean ionic activity and activity coefficients of strong electrolytes. Liquid junction potential and

membrane potential. Construction and working of metal-metal ion electrode, hydrogen electrode, calomel

electrode and oxidation- reduction electrode.

Types of cells - Electrochemical cells – primary cells (Dry cell, Daniel and Leclanche),

secondary cells (Nickel-Cadmium cell, lithium ion and lead acid) and fuel cells(hydrogen, oxygen fuel

cell). Experimental determination of EMF of cells. Derivation of Nernst equation and its significance.

Applications of EMF measurements- determination of equilibrium constant, pH and solubility product.

UNIT-V ELECTROCHEMISTRY - II

The electrical double layer- structure of electrical double layer and zeta potential. Perrin, Gouy-Chapmen

and Stern models. Butler-Volmer equation - Tafel equation. Over voltage, theories of over voltage, Types of

over voltage (Hydrogen over voltage, oxygen over voltage and metal overvoltage, importance and factors

affecting over voltage. Diffusion over potential and problem. Potentiometric titrations – principles and types

(acid- base, redox and precipitation).Conductometric titrations – principles and types (acid – base and

precipitation).

Text Books:

1. B.R.Puri, L.R.Sharma, M.S.Pathania (2012), Principles of Physical chemistry, 45th Edition,

Vishal publishing Co, New Delhi.

2. Gurdeep Raj (2004), Advanced Physical Chemitry, 30th Edition, Goel Publishing Col. Meerut.

3. R.K. Prasad (2008), Quantum Chemistry, 3rd Edition, New Age International Publishers, New Delhi.

4. S. Slasstone (1942), An Introduction to Electrochemistry, 10th Edition, East West Press (P) Ltd,

New Delhi.

Reference Books :

1. S.Glasstone (1947), Thermodynamic for Chemists, 3rd Edition, East West Press (P) Ltd., New Delhi.

2. J. Rajaram and J.C. Kuriakose (1999), Thermodynamics, 3rd Edition,

Shoban Lal Nagin, Chand & Co, New Delhi.

3. D.N. Bajpai (1992), Advanced Physical chemistry, 1st Edition, S.Chand &Company Ltd, New Delhi.

4. B.K. Sharma (1998), Electrochemistry, 5th Edition, Goel Publishing House, Meerut.

5. Dr J.N. Gurtu & A.Gurtu (2015), Advanced Physical Chemistry, 2nd Edition, Pragati Prakashan.

6. Allen J. Bard, Larry R.Faulkner (2001,)Electrochemical Method fundamentals and Application,2ndEdition,

John Wiley &Sons. Inc, New York.



Elective Course I(a) - Environmental Chemistry


M.Sc. Chemistry PCH I P20CHE11 5 4



CLO1 Study the ecological factors, functions and pollution in ecosystem.

CLO2 Acquire knowledge on different methods for the analysis of pollutants.

CLO3 Create awareness on air, soil and radioactive pollution.

CLO4 Provide knowledge in the prevention and remediation on different types of pollution.

CLO5

UNIT- I INTRODUCTION AND CLASSIFICATION OF POLLUTION

Introduction, definitions – environment, environmental science, environmental education. Types of

environment and its components. Definitions- ecology, ecosystem. Types and components of ecosystem.

Cycling of minerals, elements and gases –Phosphate cycle-Carbon cycle- Nitrogen Cycle- Hydrological

cycle. Sources, effects and control measures of various pollution - air pollution-water pollution- soil

pollution- radioactive pollution- thermal pollution- noise pollution- marine pollution.

UNIT-II ANALYSIS OF POLLUTANT

Neutron activation analysis-Anodic stripping voltametry-Atomic absorption spectrophotometry - X-

Ray Fluorescence - Inductively-Coupled Plasma Emission Spectroscopy (ICPES) - non-dispersive infrared

spectrometry -Fourier transform infrared spectroscopy- chemiluminescence

UNIT-III AIR POLLUTION

Introduction – sources of air pollution – air pollutants – classification and effects of air pollutants –

Units of measurements-oxides of nitrogen, sulphur and carbon, Hydrocarbons- acid rain-effects and control-

hydrogen sulphide – effects and control- carbon mono oxide – effects and control- photochemical smog –

effects and control – fly ash – effects and control – green house effect – global warming – effects and control

– ozone layer – ozone depletion – choloro fluoro carbons – effects and control.

UNIT- IV SOIL & RADIOACTIVE POLLUTION

Introduction- types of soil on the basis of its texture- sources of soil pollution- fertilizers and

pesticides- soil sediments as pollutant. Soil erosion –types- harmful effects-causes and its control measures.

Radioactive Pollution- Introduction, Sources of radioactive pollution and its effects. Disposal of radioactive

wastes.

UNIT- V INDUSTRIAL POLLUTION & CHEMICAL TOXICOLOGY

Introduction-causes of industrial pollution–thermal power plants-nuclear power reactors-fertilizers

and chemical industry-pulp and paper industries – agro based industries-cement industry. Toxic chemicals in

the environment –biochemical effects of arsenic, cadmium, lead, mercury and cyanide- bio-ware agents.

Recycle, Reuse, disposal and management of industrial waste.

Text Books:

1. A.K.De (Reprint 2010), Environmental Chemistry, 7th Edition, New Age International.

2. B.K.Sharma (2007), Environmental Chemistry, 11th Edition, Goel.



Elective Course I(b) - Bio Chemistry


M.Sc. Chemistry PCH I P20CHE12 5 4



CLO1 Understand the biological role of enzymes in living organism

CLO2 Teach the concept of metabolism and storage of energy with suitable examples

CLO3 Teach the concept of genetic information transmission

CLO4 Acquire the knowledge on role of metals in medicine and treatment of cancer using Pt based drugs

CLO5 Learn the principles, structures and folding of Biomolecules and their conformational analysis

UNIT-I ENZYMES

Classifications, nomenclature, properties of enzymes, some features of active sites of enzymes,

enzyme kinetics-Michaelis-Menton model-, Lineweaver-Burk and Hoftsee plot significance of Km and

Vmax Values -Enzyme inhibition-competitive and non-competitive. Allosteric interaction-Mechanism of

enzyme action .Lysozyme and carboxypeptidase.

UNIT-II GENERATION AND STORAGE OF METABOLIC ENERGY

Metabolism-basic concepts and design: glycolysis-citric acid cycle-oxidative phosphorylation-

pentose pathway and gluoneogenesis. Glycogen and disaccharide metabolism, fatty acid metabolism –amino

acid degradation and urea cycle-photosynthesis

UNIT-III INFORMATION, STORAGE, TRANSMISSION OF GENETIC INFORMATION

DNA-Genetic role structure and replication: messenger RNA and transcription genetic code and

gene protein relationship-protein synthesis, control of gene expression - Eukaryotic chromosomes,

Recombinant DNA technology and viruses.

UNIT-IV BIO-INORGANIC CHEMISTRY

Metals in Medicine: Toxicity of Fe, Cu, As, Hg, Pb, Cd, Al, Ca. Metals used in

Diagnosis:Radiodiagnostic agenta, neutron capture theraphy, MRI, X ray contrast agents. Anticancer activity

of platinum complexes: different types of active platinum complexes, toxic effects of anticancer Pt-

Complexes, mechanism of anticancer activity, nonactivity of trans-platin.

UNIT-V BIOPHYSICAL ASPECTS

Biomolecular structures - proteins - classification - conformational analysis - Ramchandran map -

nucleic acids - DNA-RNA structure and folding- protein folding - molecular forces in folding -

macromolecular-ligand interactions - binding affinities - protein-lipid interaction – biomembranes-Structural

and conformational analysis of biomacromolecules– X- Crystallography of Biomolecules- spectroscopic

methods - fluorescence– Circular Dichroism - microscopic methods – Electron Microscopy– AFM –

thermodynamics and kinetics of Biomolecular interactions - ITC - SPR – QCM.



Text Books :

1. J.L. Jain (2001), Fundamentals of Biochemistry, 5th Edition, S.Chand & company Limited, New Delhi.

2. I. Bertini, H.B.Gray S.J.Leppard and J.S Valentine (2007), Bioinorganic Chemistry, 1st Edition,

Viva Books Pvt Ltd.

3. A.L.Lehninger (1990), Biochemistry, 1st Edition, CBS publishers .

4. K.F. Purcell and J.C. Koltz (2019), An Introduction to Inorganic Chemistry, 1st Edition,

W.B. Saunders Company, Philadelpha 1980.

Reference Books:

1. B.D.Hames and N.M.Hooper (2003), Biochemistry, 1st Edition, Viva Books Ltd.

2. J.M. Berg, J.L.Tymoczko and L.Stryer (20020, Biochemistry, 5th Edition, W.H.Freeman and company,

New York.

3. Asim.K.Das (Reprinted 2013), Bio-inorganic Chemistry, 1st Edition, Books&Allied Pvt Ltd, Kolkata.



Core Course IV - Practical I - Inorganic Chemistry - I


M.Sc. Chemistry PCH I P20CHC1P1 10 4

1. SEMI-MICRO QUALITATIVE ANALYSIS: Analysis of mixtures containing two familiar and two

less familiar cations from the following W, Pb, Se, Mo, Cu, Cd, Bi,V,Ce, Th,Zr Mn, Ni, Co, Zn, Ca,

Ba, Sr, Li, Mg (insoluble and interfering an ion may be avoided).

2. INORGANIC PREPARATIONS: preparation of at least 5 inorganic complexes.

3. QUANTITATIVE ANALYSIS: separation and estimation of mixtures by volumetric and

gravimetric methods, some recommended mixtures are

i) Cu and Ni

ii) Fe and Ni

iii) Ca and Ba

iv) Cu and Zn

v) Fe and Cu

4. ESTIMATIONS: Estimation of Cu & Mg by EDTA Method (class work only)

Reference Books:

1. J. Bassett et al (1997), Vogel’s Text Book of Quantitative Chemical Analysis, 5th Edition,

ELBS, Longmann, U.K.

2. V.V. Ramanujam (2008), Inorganic Semi micro Qualitative Analysis, 3rd Edition,

The National Publishing Co, Chennai.



Core Course V - Organic Chemistry – II

(Natural Products, Conformational Analysis And Reaction Mechanism – II)


M.Sc. Chemistry PCH II P20CHE21 5 5



CLO1 Understand Neighbouring group participation and effect of structure, leaving group and solvent on

reactivity.

CLO2 Recall the concept of addition to multiple bonds.

CLO3 Know the principle of UV, IR and Mass spectroscopy and execute their application in organic

chemistry.

CLO4 Interpret about the chemistry of carbohydrates, proteins and terpenoids.

CLO5 Analyze the concept of conformational analysis.

UNIT- I ALIPHATIC NUCLEOPHILIC SUBSTITUTION

Nucleophilicity and basicity – SN1and SN2 mechanisms – Effect of substrate structure - Effect of

solvent - Effect of the attacking nucleophile – Effect of the leaving group –Effect of the reaction medium –

stereo chemistry of nucleophilic reaction -ambident nucleophiles – ambident substrates– neighbouring group

participation by n, π and σ bonds–SNi mechanism- nucleophilic substitution at an allylic and a vinylic

carbon. Classical and nonclassical carbocations, phenonium ions, norbornyl system (study only).

Aliphatic electrophilic substitution: Electrophilic substitution at saturated carbon – SE1,SE2 and SEi

mechanism.

Elimination: Elimination - E1, E2 and E1CB mechanism – stereochemistry of Elimination reaction –

orientation of the double bond– Effect of changes in the substrates base, leaving group and medium on E1,

E2, and E1CB reactions – elimination Vs substitution – pyrolytic cis eliminations – Bredts rule - dehydration

of alcohols – dehydro halogenation – cope elemination.

UNIT- II ADDITION TO MULTIPLE BONDS

Electrophilic, nucleophilic and free radical additions - addition to conjugated systems – orientation

of the addendum - stereochemical factors in reactions like addition of hydrogen, halogens, hydrogen halides

and hypohalous acids, hydroboration and hydroxylation - epoxidation. Addition to carbonyl groups –

mechanism - Aldol condensation – Perkin reaction - Knoevenagel reaction - Mannich reaction - Cannizaro

reaction – Benzoin condensation - Claisen ester condensation –Darzen’s reaction - Reformatsky reaction -

Wittig reaction – Grignard reactions.

Addition to α,β -Unsaturated carbonyl groups : Addition of Grignard reagents to α,β-unsaturated

carbonyl compounds – Michael addition – Diels-Alder reaction .

UNIT- III SPECTROSCOPY I

UV Spectroscopy: Principle- instrumentation and sampling techniques - absorption spectra of

conjugated dienes – α,β - unsaturated carbonyl compounds–Woodward-Fieser rules -Scott’s rules for

aromatic carbonyls.

IR Spectroscopy: Principle- instrumentation and sampling techniques, Molecular vibrations –

vibrational frequency - factors influencing group frequencies – quantitative studies.



Mass Spectrometry: Principle – type of ions – base peak – parent ion, meta stable and isotopic peaks

– nitrogen rule – fragmentation - general rules - pattern of fragmentation for compounds such as

hydrocarbons, amines, alcohols, ketones, acids, phenols and nitro compounds – McLafferty rearrangement –

Retro Diels-Alder reaction.

UNIT- IV CARBOHYDRATES, AMINOACIDS, PROTEINS AND TERPENOIDS

Carbohydrates: Methods used for determination of ring size – structure elucidation of maltose,

lactose and cellobiose - a brief study of starch and cellulose (structure only). Terpenoids:

Classification of terpenoids – structural elucidation of Camphor, α-pinene, zingiberene, lanosterol and

squalene.

Aminoacids and Proteins: General structure of amino acids - peptides –representation of peptide

bond-determination of the amino acid sequence of a polypeptide chain- Classification of proteins – structure

of (primary, secondary, tertiary and quaternary) peptides - structural elucidation of glutathione and oxytocin

UNIT -V CONFORMATIONAL ANALYSIS

Configuration and Conformation – Conformation of ethane, 1,2-dicholoroethane and n-butane-

conformational analysis–stereoelectronic and steric factors - conformation of simple acyclic compounds-

conformation of monosubtituted and disubstituted cyclohexanes –conformation of acyclic and cyclic

systems with their physical and chemical properties – conformational free energy – Curtin- Hammett

principle - Quantitative treatment of Mobile system - Eliel-Ro equation – conformations and reactivity of

cyclohexanones, conformation of decalins.

Text books:

1. G.R. Chatwal (2012), Reaction mechanism and reagents in organic chemistry, 5th Edition,

Himalaya Publishing House, Mumbai.

2. V.K. Ahluwalia (2007), Organic reaction mechanism, 3rd Edition, Narosa publishing House, New Delhi.

3. Somorendra Nath Sanyal (2003), Reactions, Rearrangements and Reagents, 4th Edition,

Bharati Bhawan Publishers.

4. Y.R.Sharma (2013), Elementary organic spectroscopy principles and chemical applications, 5th Edition

S.Chand and company Ltd, New Delhi.

5. P.S.Kalsi (2005), Stereochemistry conformation and Mechanism, 6th Edition, New age international

Publishers

6. G.R. Chatwal (Reprint 2010), Organic chemistry of natural products, 4th Edition, Himalaya Publishing

House, Mumbai.

Reference Books:

1. D.Nasipuri (1994), Stereochemistry of Organic Compounds, Principles and Applications , 2nd Edition,

New Age International (P) Ltd.

2. E.S. Gould (1959), Mechanism and Structure of Organic Chemistry, 1st Edition, Henry Holt& Co.,

New York ,

3. William Kemp (1991), Organic Spectroscopy, 3rd Edition, ELBS.

4. Robert M.Silverstein, Francis X. Webster (2013), Spectrometric Identification of Organic Compounds,

6th Edition, John Wiley and Sons Inc., New York.

5. P.S. Kalsi (2009), Spectroscopy of Organic Compounds, 6th Edition, New Age International Publishers.

6. Jerry March (2004), Advanced Organic Chemistry, 4th Edition, John Wiley and Sons, New York.

7. E.l.Eliel (Reprint 2008), Stereo chemistry of carbon compounds, Mc Graw Hill.



Core Course VI - Inorganic Chemistry – II (Bioorganic and Nuclear Chemistry)





CLO1 Utilize the principles of Metal ions binding to biomolecules and understanding their functions of

biological systems.

CLO2 Define the importance of inorganic elements in vital systems.

CLO3 Identify various types of nuclear changes or processes including fission, fusion and

decay reactions.

CLO4 Practice proper isotopic notation to write down and balance a nuclear reaction.

CLO5 Use different methods such as Cyclic voltammetry, TGA, Fluorimetry, Nepheometry, Turbidimetry for

estimation of different metal ions and their oxidation states.

UNIT -I BIO – INORGANIC CHEMISTRY–I

Porphyrin ring system – metalloporphyrins – hemoglobin and myoglobin structures and work functions

– synthetic oxygen carriers – cytochromes and its types – structure and work functions in respiration –

chlorophyll – structure – photosynthetic sequence – iron sulphur proteins [ non – heme iron protein] – copper

containing proteins – classification – blue copper proteins – structure of blue copper electron transferases,

copper proteins as Oxidases .

UNIT -II BIO – INORGANIC CHEMISTRY – II

Structure and function of enzyme: carboxypeptidase A–carbonic anhydrase – inhibition and poisoning

– corin ring system – vitamin B12 and B12 Coenzymes – in – vivo and in – vitro nitrogen fixation – essential

and trace elements in biological systems- metal ion toxicity(Cu, Cd Fe, Pb, Hg, Cr) and its detoxification -

sodium and potassium ions pumps –chelate therapy – cis platin.

UNIT- III STRUCTURE OF NUCLEUS AND RADIOACTIVE DECAY

Composition of the nucleus –nuclear Size, shape and density-principle, radial and magnetic

quantum numbers n/p ratio- stability of nucleus packing fraction--mass defect and binding energy.

Radioactive decay: Group displacement law – decay series – rate of disintegration -half life period -average

life period – secular and transient equilibria - theories of alpha decay, beta decay, gamma emission, internal

conversion and electron capture - Auger effect.

UNIT- IV NUCLEAR FISSION AND FUSION AND APPLICATION RADIOACTIVE ISOTOPES:

Bethe's notation of nuclear process - nuclear reaction energies (Q-values) – fission-energy release

in nuclear fission-mass distribution of fission products-theory of nuclear fission -fissile and fertile isotopes –

energy from nuclear fusion-thermonuclear reaction instars - nuclear reactor--breeder reactor- waste disposal

management. Applications of radioactive isotopes: - chemical investigations-age determination-medical

field-agriculture and analytical techniques.



UNIT- V ANALYTICAL METHODS

Electro analytical Techniques: Electrogravimetry, Theory of electro gravimetric analysis -

electrolytic separation and determination of metal ions. Coulometry – Coulometric titrations. Voltametry:

Cyclic voltammetry. Amperometry: Amperometric titrations. Thermo analytical Methods: Principle and

applications of TGA and DTA. Spectro analytical Methods: principle and applications of Fluorimetry,

Nepheometry, Turbidimetry – Flame photometry and Atomic absorptions spectroscopy.

Text books:

1. James E. Huheey, Ellen A. Keitler and Richard L. Keitler (2003), Inorganic Chemistry-principles of

structure and reactivity, 4th Edition, Harper Collins College Publishers.

2. P.W.Atkins, Overton, Rourke, Weller, Armstrong (Reprinted 2011), Inorganic Chemistry, 4th Edition,

Oxford University Press.

3. U.N.Dash (1991), Nuclear Chemistry, 1st Edition, Sultan Chand and Sons, New Delhi

4. H.I. Arnikar (1987), Essential of Nuclear Chemistry, 3rd Edition, Wiley Eastern Ltd., New Delhi.

5. Gurdeep R.Chatwal (2008), Instrumental Methods of chemical Analysis, 5th Edition,

Himalaya Publishing House.

Reference Books:

1. Asim.K.Das (Reprinted 2013), Bio-inorganic Chemistry, 1st Edition, Books &Allied Pvt Ltd, Kolkata.

2. M.N. Hughes (1984), The Inorganic Chemistry of Biological process, 2nd Edition, Wiley Intersciences,

New York.

3. S.Glasstone (1967), Source Book on Atomic Energy, 3rd Edition, Van Nostrand Reinhold Company,

New York.

4. G. Friedlander (1981), Nuclear and Radiochemistry, John-Wiley and Sons, Inc., New York.

5. D.A .Skoog and D.M. Weat (1982), Fundamentals of Analytical Chemistry, 1st Edition,

Saunders College Publishing co Philadelphia.



Core Course VII - Physical Chemistry – II

(Quantum, Catalysis and Molecular Spectroscopy-I)


M.Sc. Chemistry PCH II P20CHC23 5 5



CLO1 Apply the technique of separation of variable to solve problems in more than one dimension and

to understand the role of degeneracy of electron shell structure in atom.

CLO2 Apply the approximation methods to obtain energies and wave function for quantum mechanical

system.

CLO3 Acquire the knowledge of theoretical background of statistical thermodynamics.

CLO4 Understand the chemistry associated with the use of catalyst, enzyme and evaluating the reaction

mechanism & rate expression for catalytic reaction.

CLO5 Analyse and interpret spectroscopic data by IR.

UNIT- I APPLICATION OF QUANTUM MECHANICS TO SIMPLE SYSTEMS

Derivation of Schrodinger wave equation (SWE). Application of SWE to simple systems - particle

moving in one dimensional box, particle moving in a 3-D box- degeneracy – distortion, particle moving in a

ring, rigid rotator, simple harmonic oscillator. Rotation of molecule and their spectra, Radial wave function

and radial probability distribution function. Shapes of various atomic orbitals. The concept of tunneling,

shapes of the barrier and tunneling in hydrogen transfer reactions.

UNIT- II APPROXIMATION METHODS IN QUANTUM MECHANICS

Need for approximation methods (variation and Perturbation methods). Perturbation corrections-first

order correction. Schrodinger equation for He atom. Variation theorem- application to hydrogen and He

atoms. Hartee - Fock Self Consistent Field (HFSCF) theory- application to He atom, HFSCF method of

many electron system. Electron spin and Pauli principle, anti symmetric nature of the wave functions, Slater

rules and Born-Oppenheimer approximation. The Linear combination of atomic orbital approximation

(LCAO) and MO method for hydrogen molecule (H2).

UNIT- III STATISTICAL THERMODYNAMICS-I

Aims of statistical thermodynamics, definitions of state of a system, ensembles and their types,

micro and macro states, thermodynamic probability. Derivation of Boltzmann distribution law. Quantum

statistics – derivation of Fermi-Dirac and Bose-Einstein statistics. Comparison of Maxwell-Boltzmann,

Bose-Einstein and Fermi-Dirac statistics, bosons and fermions. Problems on distribution laws-photon gas

and electron gas. Boltzmann-Planck equation.

UNIT- IV CATALYSIS

Catalysis - Types, characteristics and theory of catalysis. Heterogeneous catalysis- kinetics,

retardation and effect of temperature. Mechanism of Heterogeneous catalysis- Langmuir – Heinshelwood

and Langmuir – Rideal- mechanism- Classification of catalysis. Enzyme catalysis – characteristics- factors

governing the rate of enzyme reaction- Mechanism and its kinetics (Michaelis Menten equation), Line

weaver - Burk plot and Eadie’s plot. Acid–Base catalysis –Mechanism and its kinetics. Hammett and

Bronsted equation, Acidity function. .



UNIT-V MOLECULAR SPECTROSCOPY-I

Electromagnetic spectrum. Types of molecular energies. Absorption and emission of radiation.

Einstein’s coefficient-induced emission and absorption. Rotational spectra of rigid diatomic molecules-

isotope effect in rotational spectra. Microwave spectrometer. Information derived from rotational spectra.

Infrared spectroscopy: Vibrational energy of diatomic molecule-infrared selection rules-diatomic vibrating

rotator. Vibrations of polyatomic molecules - overtone, combination and difference bands. Concept of group

frequencies - coupling interaction. Fermi resonance-FT-IR.

Text Books:

1. A.K.Chandra (2002), Introductory Quantum chemistry, 4th Edition, Tata McGraw –Hill

Publishing Company Limited, New Delhi.

2. B.R. Puri, LR. Sharma, M.S. Pathania (2012), Principles of Physical Chemistry, 45th Edition,

Vishal Publishing Co. New Delhi.

3. Gurdeep Raj (2004), Advanced Physical chemistry, 30th Edition, Goel Publishing Co, Meerut.

4. Colin N. Banwell and Elaine M.McCash (2003), Fundamentals of molecular spectroscopy, 4th Edition,

Tata McGraw- Hill Publishing Company Limited.

Reference Books:

1. R.K.Prasad (2006), Quantum chemistry, 3rd Edition, New Age International Publishers, New Delhi.

2. G.Aruldhas (2009), Molecular structure and spectroscopy, 2nd Edition, PHI Learning (P) Limited,

New Delhi.

3. A.W.Adamson (1990), Physical chemistry of surfaces, 5th Edition, John Wiley & sons, New York.



Elective Course II(a) - Analytical Chemistry





CLO1 The primary objective is to provide knowledge on the background in the analytical chemistry and

apply the concept to analyze the data.

CLO2 Impart the knowledge about principles of precipitation techniques.

CLO3 Understand the various concepts in chromatography and execute the techniques to identify the

components.

CLO4 Understand the basic principle and instrumentation of thermo analytical technique and assess the

thermal stability of a compound.

CLO5 Demonstrate in detail the elcetro analytical and spectro analytical methods and apply the methods to

predict the configuration of some simple compounds.

UNIT-I PRECIPITATION TECHNIQUES

Introduction-properties of precipitates and precipitating reagents –colloidal precipitates,

Coprecipitation-post precipitation –precipitates from homogeneous solution – surface adsorption –drying and

ignition of precipitates –application of gravimetric methods

UNIT-II SOLVENT EXTRACTION

Chromatography- Introduction, classification of chromatographic methods, column

chromatography techniques- columns, adsorbents, methods, HPLC techniques-adsorbents, detection

methods, estimations, GC-MS techniques-methods, principles and uses.

UNIT-III ELECTRO ANALYTICAL METHODS

Voltammetry: Cyclic voltammetry – stripping voltammetry - chronopoteniometry. Amperometry:

Amperometric titrations.

Coulometry: Electrolytic cell-working electrodes-auxiliary electrode and reference electrode-

coulometric titrations

Electrogravimetry, theory of eletrogravimetric analysis- electrolytic separation and Applications.

UNIT-IV THERMOANALYTICAL METHODS

Thermogravimetry (TG): Theory and principles- factors affecting TG curves-Instrumentation and

Applications of TG.

Differential Thermal Analysis (DTA): Theory and principles- factors affecting DTA curves-

Instrumentation and Applications of DTA.

Application of TGA and DTA to the following compounds-crystalline coppersulphate, calcium oxalate

monohydrate, calcium acetate monohydrate, zinc hexafluosilicate-complementary nature of DTA and TGA.

Differential Scanning Calorimetry (DSC): principle-phase transition study and application of DSC

in forensic laboratory.



UNIT-V SPECTROANALYTICAL METHODS

Colorimetry: Beer and Lambert’s law-terminology-condition for a satisfactory colorimetric

analysis-method of colour measurement or comparison-principles of colorimetric determinations of NH3, Cr,

Cu, Fe, Mn-simultaneous spectrophotometer determination of Cr and Mn.

Nephelometry and turbidimetry: principle-determination of sulphate and phosphate

fluorimetry: principle-application of fluorimetry in the determination of Cd,Ca,and Zn and determination of

codeine and morphine in a mixture

Flame spectrometry: theory- interferences-AAS-applications in the determination of Mg+2 and

Ca+2 in tap water,V in lubricating oil, trace lead in a ferrous alloy and trace elements in contaminated soil.

Text Books:

1. R. Gopalan (2003), Elements of analytical Chemistry, 3rd Edition, Sultan Chand & sons, New Delhi.

2. Gurdeep chatwal (2012), Instrumental method of chemical analysis, 5th Edition,

Himalaya publishing House, Mumbai.

Reference Books:

1. D.A.Skoog, D.M.West and F.J.Hollar (1996), Fundamentals of Analytical Chemistry, 7th Edition,

Harcourt College Publishers.

2. H.H.Williard,L.L.Merritt and J.A.Dean (1988), Instrumental Methods of Analysis, 1st Edition,

East-West press, New Delhi.

3. U.N Dash(2013), Analytical chemistry, 3rd Edition, Sultan Chand & sons, New Delhi.

4. J. Bassett et al (1997), Vogel’s Text Book of Quantitative Chemical Analysis, 5th Edition,

ELBS, Longmann, U.K.

5. J.G. Dick (1973), Analytical chemistry, 1st Edition, Tata-McGraw Hill.



Elective Course II(b) - Applied Chemistry





CLO1 Understand the chemistry of dairy and leather processing and apply the concept to predict the quality

of dairy and leather.

CLO2 Acquire knowledge about functions of Portland cement.

CLO3 Learn about the technology and applications of polymers.

CLO4 Know the significance of bomb scene management and locate hidden explosives.

CLO5

Unit-I: Dairy Chemistry

Composition and structure of milk - factors affecting the composition of milk - Properties of milk-

Flavour and Aroma, Density of milk - Effect of heat on milk, Milk Processing - Clarification, Pasteurization-

Homogenization. Milk products – Butter, Ice cream, Sweeteners.

Unit-II: Leather Chemistry

Introduction – structure of skins and hides - Leather Processing – cleaning and soaking, liming and

degreasing, fleshing, Shaving – Leather Tanning – Vegetable and Chrome Tanning. Leather finishing.

Tannery effluents – pollution and control.

Unit – III: Portland Cement

Manufacture of cement, Dry and Wet process, Important process parameters for

manufacturing a good cement clinker. Characteristics of the constitutional compounds of cement.

Additives for cement, Properties, General composition, Testing of cement, Chemical & physical

requirement.

Unit – IV: Polymer Science and Technology

Manufacturing process - raw materials - composition and Engineering uses of the following:

Polyethylene (PVC), Teflon -- synthetic fibres (Nylon66, Nylon 6, Terylene) - natural Rubber- Refining of

crude rubber - Vulcanization of rubber and Synthetic rubbers (BunaS, Neoprene) - fertilizers(Nitrogen and

phosphate)- Organic insecticides (DDT,BHC)

Unit – V: Forensic Chemistry

Classification of explosives – low explosives and high explosives. Homemade explosives. Military

explosives. Blasting agents.

Synthesis and characteristics of TNT, PETN and RDX. Explosion process. Blast waves.

Bomb scene management.

Searching the scene of explosion. Mechanism of explosion. Post blast residue collection and analysis.

Blast injuries. Detection of hidden explosives.

Text Books:

1. K. Bagavathi Sundari (2008), Applied Chemistry, MJP Publication.

2. V.R.Gowarikar, N.V.Viswanathan and Jayadev Sreedher (1986), Polymer Science, 4th Edition,

Wiley Eastern Ltd., New Delhi.



Core Course VIII (P) - Practical I - Organic Chemistry - I


M.Sc. Chemistry PCH II P20CHC2P1 10 4

QUALITATIVE ANALYSIS

Separation and analysis of two component mixtures. Identification of the components and

preparation of solid derivative.

QUANTITATIVE ANALYSIS

a. Estimation of glucose by Lane and Eynon method.

b. Estimation of glucose by Bertrand method.

c. Estimation of glycine.

d. Estimation of formaldehyde.

e. Estimation of ethylmethyl ketone.

f. Estimation of acetone.

g. Estimation of ascorbic acid.

ORGANIC PREPARATIONS: (ONLY FOR CLASS WORK)

About 5 (five) two stage preparations:

a. p-Nitroaniline from acetanilide.

b. Anthranilic acid from phthalimide.

c. m-Nitrobenzoic acid from methyl benzoate.

d. Benzanilide from benzophenone.

e. Acetylsalicylic acid from salicylic acid.

Reference books:

1. A.I. Vogel (1966), Small Scale Preparations, 2nd Edition, ELSB.

2. V.Venkateswaran, R.Veerasamy, A.R Kulandaivelu (1995), Basic principles of practical Chemistry,

1st Edition, Sultan chand & sons Publishers, New Delhi.

3. S. Murugan (1988), A Laboratory Manual of Organic Chemistry, 3rd Edition, Bharathi Press.

4. J.N Gurtu and R.Kapoor (1982), Advanced experimental Chemistry, 2nd Edition,

S.Chand and Company Limited, New Delhi.

Ms K. Rajasulochana (Dr D.K. Nathan)

Chairman Dean-Academic Affairs

Documents

PG Degree Course in M.Sc. (Chemistry) Programme Code : PCHsrnmcollege.ac.in/event_img/84666c22dfc097ed3830efafb7dc38cf6… · nomenclature - pro-R and pro-S and Re and Si faces -