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Research of polymer based bio-sensors PhD student introduction abor Orb´ an Gergely M´ arton, PhD ICNP RCNS HAS 25 May 2017

PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

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Page 1: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Research of polymer based bio-sensorsPhD student introduction

Gabor Orban

Gergely Marton, PhD ICNP RCNS HAS

25 May 2017

Page 2: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Educations - Bachelor degree

BUTE - electrical engineer

microelectronics

Institute of Technical Physicsand Materials Science, HAS

bioelectrical activity of brainmeasuring options

Gabor Orban Research of polymer based bio-sensors 2 / 9

Page 3: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Educations - Bachelor degree

BUTE - electrical engineer

microelectronics

Institute of Technical Physicsand Materials Science, HAS

bioelectrical activity of brainmeasuring optionsdesign a polymer based microelectrodesystem

Gabor Orban Research of polymer based bio-sensors 3 / 9

Page 4: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Educations - Bachelor degree

BUTE - electrical engineer

microelectronics

Institute of Technical Physicsand Materials Science, HAS

bioelectrical activity of brainmeasuring optionsdesign a polymer basedmicroelectrode systemin vivo validation

Gabor Orban Research of polymer based bio-sensors 4 / 9

Page 5: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Educations - Master degree

BUTE - electrical engineer

smart system integration

Institute of CognitiveNeuroscience and Psychology,RCNS, HAS

flexible electrode insertionmethod

Department of Oral Diagnostics,FD, SE

dental researchpolymer based electrodebioelectrical activityNervus trigeminus

[Henry Gtay: Anatomy of the Human Body, 1918]

Gabor Orban Research of polymer based bio-sensors 5 / 9

Page 6: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

From brain electrodes to a dental research

Anatomy of the tooth

Dentin recording

Pain from tooth nerve

Neuroplasticity

[www.budadent.hu, 2016]

Gabor Orban Research of polymer based bio-sensors 6 / 9

Page 7: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Motivation and goals

Application of dentin recording

Measuring the dental nerve activity in high resolution on the dentinsurface allows us to scan the inflammation process into the pulp becauseof the neuroplasticity.

scan the process of the neuroplasticity

localization of the source of the pain stimulus

numerical method of toothache

Remaining Dentin Thickness

Measuring the impedance of the dentin in high resolution on the dentinsurface allows us to calculate the remaining dentin thickness.

Gabor Orban Research of polymer based bio-sensors 7 / 9

Page 8: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

PhD thesis goals

develop an electrode system to measure:

remaining dentin thickness during a dental interventionpulp vitality with measuring the dental nerve activities on the surfaceof dentindental pain because of the neuroplasticity

in vivo validation of the electrode

using the electrode to develop a tool for clinical applications

Gabor Orban Research of polymer based bio-sensors 8 / 9

Page 9: PhD student introduction G abor Orb anatdi.uni-obuda.hu/.../7-hazikonferencia-2017-orban-gabor.pdf · 2017. 5. 30. · PLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely,

Publications

A Multimodal, SU-8-Platinum - Polyimide Microelectrode Array forChronic In Vivo NeurophysiologyPLOS ONE 10:(12) Paper e0145307. 16 p. (2015), Marton Gergely, Orban Gabor, Kiss Marcell, Fiath Richard,

Pongracz Anita, Ulbert Istvan

A polymer-based spiky microelectrode array for electrocorticographyMICROSYSTEM TECHNOLOGIES 21:(3) pp. 619-624. (2015), Gergely Marton, Marcell Kiss, Gabor Orban, Anita

Pongracz, Istvan Ulbert

A Novel Polyimide – Platinum – SU-8 Microelectrode Array forVarious Electrophysiological ApplicationsPROCEDIA ENGINEERING 87: pp. 380-383. (2014) Eurosensors 2014, Gergely Marton, Gabor Orban, Marcell Kiss,

Anita Pongracz, Istvan Ulbert

MEMS erzekelok a neurofiziologiabanMTA Termeszettudomanyi Kutatokozpont Doktori Konferencia, Budapest, 2014. pp. 56-57. (ISBN:978-963-7067-28-0),

Marton Gergely, Orban Gabor, Fiath Richard, Bakos Istvan, Fekete Zoltan, Pongracz Anita, Ulbert Istvan

Gabor Orban Research of polymer based bio-sensors 9 / 9