2
404 " XBD=328 XHG=100 YBD=236 YHG=201>difficulties " XBD=398 XHG=355 YBD=236 YHG=202>in " XBD=496 XHG=424 YBD=237 YHG=202>the " XBD=803 XHG=523 YBD=237 YHG=204>maintenance " XBD=876 XHG=831 YBD=236 YHG=202>of " XBD=953 XHG=900 YBD=236 YHG=213>an " XBD=1180 XHG=980 YBD=246 YHG=202>adequate " XBD=1300 XHG=1209 YBD=237 YHG=211>con- " XBD=342 XHG=103 YBD=292 YHG=250>centration, " XBD=440 XHG=364 YBD=285 YHG=251>but " XBD=575 XHG=460 YBD=286 YHG=252>these " XBD=697 XHG=595 YBD=286 YHG=262>were " XBD=867 XHG=715 YBD=295 YHG=250>largely " XBD=1107 XHG=886 YBD=291 YHG=261>overcome, " XBD=1212 XHG=1130 YBD=285 YHG=251>and " XBD=1302 XHG=1231 YBD=284 YHG=250>the " XBD=351 XHG=102 YBD=343 YHG=298>application " XBD=419 XHG=374 YBD=334 YHG=299>of " XBD=642 XHG=438 YBD=345 YHG=299>penicillin " XBD=710 XHG=665 YBD=333 YHG=310>as " XBD=905 XHG=733 YBD=343 YHG=298>powder, " XBD=1107 XHG=931 YBD=332 YHG=298>solution " XBD=1174 XHG=1129 YBD=333 YHG=309>or " XBD=1300 XHG=1197 YBD=333 YHG=299>oint- " XBD=215 XHG=103 YBD=382 YHG=350>ment " XBD=396 XHG=242 YBD=393 YHG=348>proved " XBD=466 XHG=422 YBD=382 YHG=360>as " XBD=708 XHG=494 YBD=392 YHG=347>strikingly " XBD=949 XHG=734 YBD=380 YHG=346>successful " XBD=1019 XHG=975 YBD=380 YHG=357>as " XBD=1117 XHG=1046 YBD=381 YHG=346>did " XBD=1303 XHG=1143 YBD=391 YHG=346>general " XBD=432 XHG=103 YBD=431 YHG=395>administration " XBD=493 XHG=449 YBD=430 YHG=397>in " XBD=700 XHG=511 YBD=440 YHG=395>systemic " XBD=943 XHG=718 YBD=429 YHG=394>infections. " XBD=262 XHG=154 YBD=479 YHG=444>Here " XBD=339 XHG=279 YBD=479 YHG=456>we " XBD=461 XHG=355 YBD=479 YHG=446>have " XBD=504 XHG=479 YBD=478 YHG=455>a " XBD=738 XHG=523 YBD=478 YHG=444>substance " XBD=889 XHG=756 YBD=477 YHG=443>whose " XBD=1159 XHG=905 YBD=488 YHG=443>therapeutic " XBD=1302 XHG=1177 YBD=488 YHG=444>possi- " XBD=251 XHG=104 YBD=527 YHG=491>bilities " XBD=370 XHG=264 YBD=527 YHG=493>have " XBD=480 XHG=383 YBD=536 YHG=492>only " XBD=626 XHG=492 YBD=536 YHG=491>begun " XBD=682 XHG=638 YBD=524 YHG=494>to " XBD=747 XHG=696 YBD=524 YHG=491>be " XBD=962 XHG=760 YBD=536 YHG=490>explored, " XBD=1132 XHG=977 YBD=537 YHG=491>though " XBD=1304 XHG=1147 YBD=527 YHG=491>clinical " XBD=217 XHG=104 YBD=576 YHG=541>trials " XBD=413 XHG=256 YBD=575 YHG=540>started " XBD=564 XHG=449 YBD=574 YHG=540>three " XBD=717 XHG=602 YBD=584 YHG=549>years " XBD=843 XHG=756 YBD=584 YHG=550>ago. " XBD=1185 XHG=898 YBD=575 YHG=540>Practitioners " XBD=1304 XHG=1223 YBD=575 YHG=540>will " XBD=267 XHG=105 YBD=629 YHG=590>wonder " XBD=391 XHG=287 YBD=630 YHG=600>now, " XBD=449 XHG=414 YBD=622 YHG=587>if " XBD=566 XHG=465 YBD=632 YHG=588>they |>" XBD=785 XHG=586 YBD=622 YHG=588>have not " XBD=1018 XHG=806 YBD=623 YHG=589>wondered " XBD=1187 XHG=1039 YBD=630 YHG=589>before, " XBD=1304 XHG=1210 YBD=634 YHG=590>why " XBD=280 XHG=104 YBD=683 YHG=638>supplies " XBD=371 XHG=303 YBD=671 YHG=648>are " XBD=468 XHG=394 YBD=671 YHG=639>not " XBD=570 XHG=491 YBD=680 YHG=639>yet " XBD=787 XHG=585 YBD=681 YHG=636>generally " XBD=1020 XHG=810 YBD=678 YHG=636>available, " XBD=1127 XHG=1045 YBD=672 YHG=638>and " XBD=1230 XHG=1149 YBD=671 YHG=637>will " XBD=1303 XHG=1253 YBD=671 YHG=638>be " XBD=389 XHG=104 YBD=731 YHG=685>disappointed " XBD=459 XHG=414 YBD=719 YHG=687>to " XBD=584 XHG=486 YBD=719 YHG=685>read " XBD=676 XHG=606 YBD=719 YHG=684>the " XBD=905 XHG=697 YBD=721 YHG=685>FLOREYS’ " XBD=1115 XHG=930 YBD=730 YHG=685>tailpiece " XBD=1303 XHG=1137 YBD=731 YHG=685>holding " XBD=177 XHG=105 YBD=768 YHG=737>out " XBD=247 XHG=193 YBD=768 YHG=745>no " XBD=471 XHG=263 YBD=779 YHG=736>prospects " XBD=534 XHG=488 YBD=768 YHG=733>of " XBD=616 XHG=545 YBD=768 YHG=734>the " XBD=819 XHG=633 YBD=779 YHG=734>shortage " XBD=953 XHG=835 YBD=779 YHG=734>being " XBD=1068 XHG=970 YBD=769 YHG=745>soon " XBD=1300 XHG=1083 YBD=769 YHG=734>remedied. " XBD=188 XHG=104 YBD=817 YHG=782>The " XBD=298 XHG=207 YBD=817 YHG=783>best " XBD=375 XHG=315 YBD=817 YHG=793>we " XBD=471 XHG=395 YBD=817 YHG=794>can " XBD=595 XHG=489 YBD=829 YHG=783>hope " XBD=676 XHG=613 YBD=818 YHG=782>for " XBD=728 XHG=695 YBD=818 YHG=784>is " XBD=905 XHG=748 YBD=829 YHG=783>enough " XBD=987 XHG=924 YBD=818 YHG=783>for " XBD=1107 XHG=1005 YBD=818 YHG=782>local " XBD=1301 XHG=1126 YBD=829 YHG=782>applica- " XBD=192 XHG=105 YBD=868 YHG=832>tion " XBD=284 XHG=211 YBD=867 YHG=835>not " XBD=374 XHG=303 YBD=867 YHG=835>too " XBD=488 XHG=393 YBD=878 YHG=832>long " XBD=650 XHG=508 YBD=874 YHG=833>ahead, " XBD=733 XHG=670 YBD=868 YHG=832>for " XBD=777 XHG=753 YBD=867 YHG=845>a " XBD=972 XHG=796 YBD=868 YHG=833>mastoid " XBD=1138 XHG=990 YBD=867 YHG=833>wound " XBD=1234 XHG=1157 YBD=866 YHG=843>can " XBD=1303 XHG=1253 YBD=867 YHG=831>be " XBD=254 XHG=106 YBD=926 YHG=880>locally " XBD=436 XHG=276 YBD=916 YHG=882>treated " XBD=560 XHG=460 YBD=916 YHG=883>with " XBD=725 XHG=588 YBD=924 YHG=884>15,000 " XBD=905 XHG=751 YBD=917 YHG=882>Oxford " XBD=1050 XHG=928 YBD=923 YHG=882>units, " XBD=1253 XHG=1078 YBD=916 YHG=882>whereas " XBD=1304 XHG=1279 YBD=916 YHG=893>a " XBD=430 XHG=105 YBD=976 YHG=930>staphylococcal " XBD=708 XHG=464 YBD=977 YHG=931>septicaemia " XBD=838 XHG=742 YBD=975 YHG=942>may " XBD=973 XHG=871 YBD=966 YHG=931>need " XBD=1099 XHG=1006 YBD=964 YHG=931>that " XBD=1304 XHG=1133 YBD=965 YHG=934>amount " XBD=292 XHG=106 YBD=1025 YHG=978>3-hourly " XBD=367 XHG=304 YBD=1014 YHG=978>for " XBD=522 XHG=379 YBD=1015 YHG=980>weeks. " XBD=660 XHG=577 YBD=1014 YHG=980>The " XBD=872 XHG=673 YBD=1014 YHG=979>technical " XBD=1111 XHG=884 YBD=1014 YHG=979>difficulties " XBD=1301 XHG=1124 YBD=1024 YHG=978>of large- " XBD=210 XHG=106 YBD=1063 YHG=1028>scale " XBD=510 XHG=228 YBD=1063 YHG=1027>manufacture " XBD=634 XHG=528 YBD=1063 YHG=1029>have " XBD=722 XHG=653 YBD=1074 YHG=1032>yet " XBD=785 XHG=741 YBD=1063 YHG=1032>to " XBD=854 XHG=804 YBD=1063 YHG=1028>be " XBD=1082 XHG=874 YBD=1063 YHG=1040>overcome " XBD=1183 XHG=1101 YBD=1063 YHG=1028>and " XBD=1305 XHG=1201 YBD=1063 YHG=1039>even " XBD=149 XHG=107 YBD=1112 YHG=1078>in " XBD=232 XHG=162 YBD=1112 YHG=1078>the " XBD=481 XHG=246 YBD=1122 YHG=1076>laboratory " XBD=616 XHG=495 YBD=1112 YHG=1078>much " XBD=772 XHG=632 YBD=1113 YHG=1077>skilled " XBD=896 XHG=786 YBD=1112 YHG=1078>work " XBD=1045 XHG=910 YBD=1124 YHG=1078>brings " XBD=1135 XHG=1059 YBD=1113 YHG=1078>but " XBD=1173 XHG=1149 YBD=1112 YHG=1090>a " XBD=1306 XHG=1188 YBD=1112 YHG=1077>small " XBD=255 XHG=104 YBD=1160 YHG=1129>return. " XBD=394 XHG=308 YBD=1161 YHG=1126>The " XBD=508 XHG=407 YBD=1172 YHG=1127>drug " XBD=555 XHG=521 YBD=1160 YHG=1127>is " XBD=707 XHG=567 YBD=1172 YHG=1127>highly " XBD=925 XHG=719 YBD=1162 YHG=1126>labile-it " XBD=971 XHG=937 YBD=1161 YHG=1127>is " XBD=1138 XHG=983 YBD=1172 YHG=1127>readily " XBD=1305 XHG=1151 YBD=1162 YHG=1127>broken " XBD=222 XHG=104 YBD=1210 YHG=1175>down " XBD=297 XHG=240 YBD=1220 YHG=1175>by " XBD=425 XHG=314 YBD=1210 YHG=1175>acids " XBD=527 XHG=444 YBD=1210 YHG=1176>and " XBD=701 XHG=545 YBD=1218 YHG=1176>alkalis, " XBD=778 XHG=721 YBD=1221 YHG=1176>by " XBD=903 XHG=795 YBD=1218 YHG=1176>heat, " XBD=980 XHG=924 YBD=1222 YHG=1176>by " XBD=1152 XHG=1000 YBD=1211 YHG=1177>certain " XBD=1305 XHG=1170 YBD=1221 YHG=1176>heavy " XBD=259 XHG=103 YBD=1266 YHG=1224>metals, " XBD=367 XHG=285 YBD=1259 YHG=1225>and " XBD=517 XHG=394 YBD=1268 YHG=1225>(most " XBD=691 XHG=541 YBD=1260 YHG=1226>serious " XBD=762 XHG=717 YBD=1260 YHG=1225>of |>" XBD=852 XHG=783 YBD=1274 YHG=1225>all) " XBD=937 XHG=881 YBD=1271 YHG=1226>by " XBD=1086 XHG=961 YBD=1271 YHG=1237>many " XBD=1304 XHG=1110 YBD=1260 YHG=1225>bacterial " XBD=289 XHG=102 YBD=1319 YHG=1284>enzymes " XBD=433 XHG=303 YBD=1309 YHG=1273>which " XBD=586 XHG=447 YBD=1309 YHG=1285>means " XBD=694 XHG=601 YBD=1310 YHG=1275>that " XBD=949 XHG=708 YBD=1321 YHG=1275>production " XBD=1072 XHG=962 YBD=1309 YHG=1277>must " XBD=1137 XHG=1087 YBD=1309 YHG=1274>be " XBD=1307 XHG=1152 YBD=1309 YHG=1275>carried " XBD=176 XHG=103 YBD=1358 YHG=1326>out " XBD=297 XHG=198 YBD=1358 YHG=1323>with " XBD=436 XHG=320 YBD=1358 YHG=1324>strict " XBD=623 XHG=459 YBD=1369 YHG=1325>asepsis. " XBD=815 XHG=676 YBD=1359 YHG=1324>Funds " XBD=899 XHG=837 YBD=1359 YHG=1323>for " XBD=1104 XHG=921 YBD=1359 YHG=1324>research " XBD=1194 XHG=1126 YBD=1359 YHG=1336>are " XBD=1306 XHG=1218 YBD=1358 YHG=1324>said " XBD=147 XHG=103 YBD=1407 YHG=1375>to " XBD=221 XHG=171 YBD=1407 YHG=1372>be " XBD=390 XHG=245 YBD=1418 YHG=1372>ample, " XBD=499 XHG=416 YBD=1408 YHG=1373>and " XBD=712 XHG=522 YBD=1419 YHG=1374>Imperial " XBD=937 XHG=736 YBD=1408 YHG=1373>Chemical " XBD=1185 XHG=960 YBD=1408 YHG=1373>Industries " XBD=1303 XHG=1208 YBD=1408 YHG=1373>Ltd. " XBD=148 XHG=104 YBD=1456 YHG=1432>as " XBD=256 XHG=167 YBD=1456 YHG=1420>well " XBD=318 XHG=273 YBD=1456 YHG=1433>as " XBD=408 XHG=337 YBD=1456 YHG=1422>the " XBD=516 XHG=427 YBD=1457 YHG=1433>new " XBD=800 XHG=534 YBD=1468 YHG=1423>Therapeutic " XBD=1021 XHG=820 YBD=1457 YHG=1423>Research " XBD=1306 XHG=1040 YBD=1468 YHG=1422>Corporation " XBD=172 XHG=104 YBD=1505 YHG=1481>are " XBD=396 XHG=214 YBD=1516 YHG=1470>tackling " XBD=511 XHG=440 YBD=1505 YHG=1472>the " XBD=822 XHG=556 YBD=1517 YHG=1471>outstanding " XBD=1080 XHG=866 YBD=1517 YHG=1472>problems. " XBD=1191 XHG=1134 YBD=1506 YHG=1471>At " XBD=1305 XHG=1235 YBD=1506 YHG=1472>the " XBD=267 XHG=103 YBD=1565 YHG=1522>request " XBD=330 XHG=284 YBD=1555 YHG=1519>of " XBD=416 XHG=344 YBD=1555 YHG=1521>the " XBD=625 XHG=434 YBD=1565 YHG=1520>Ministry " XBD=689 XHG=643 YBD=1555 YHG=1520>of " XBD=872 XHG=704 YBD=1566 YHG=1520>Supply, " XBD=917 XHG=892 YBD=1554 YHG=1532>a " XBD=1178 XHG=935 YBD=1566 YHG=1520>production " XBD=1314 XHG=1198 YBD=1555 YHG=1532>com-- " XBD=245 XHG=103 YBD=1604 YHG=1569>mittee " XBD=302 XHG=257 YBD=1604 YHG=1571>to " XBD=517 XHG=315 YBD=1615 YHG=1569>integrate " XBD=644 XHG=530 YBD=1604 YHG=1570>these " XBD=797 XHG=658 YBD=1604 YHG=1569>efforts " XBD=884 XHG=811 YBD=1604 YHG=1570>has " XBD=1000 XHG=898 YBD=1604 YHG=1569>been " XBD=1075 XHG=1014 YBD=1604 YHG=1572>set " XBD=1158 XHG=1089 YBD=1615 YHG=1581>up, " XBD=1304 XHG=1172 YBD=1615 YHG=1581>repre- " XBD=263 XHG=104 YBD=1665 YHG=1618>senting " XBD=357 XHG=285 YBD=1653 YHG=1618>the " XBD=534 XHG=380 YBD=1654 YHG=1618>British " XBD=668 XHG=558 YBD=1653 YHG=1618>firms " XBD=912 XHG=691 YBD=1653 YHG=1619>interested " XBD=1017 XHG=935 YBD=1653 YHG=1620>and " XBD=1111 XHG=1039 YBD=1653 YHG=1619>the " XBD=1305 XHG=1133 YBD=1654 YHG=1619>Medical " XBD=307 XHG=105 YBD=1703 YHG=1668>Research " XBD=507 XHG=329 YBD=1703 YHG=1667>Council. " XBD=769 XHG=556 YBD=1702 YHG=1668>American " XBD=899 XHG=789 YBD=1702 YHG=1667>firms " XBD=1099 XHG=920 YBD=1713 YHG=1668>working " XBD=1174 XHG=1121 YBD=1703 YHG=1680>on " XBD=1303 XHG=1194 YBD=1713 YHG=1669>peni- " XBD=213 XHG=107 YBD=1751 YHG=1717>cillin " XBD=340 XHG=233 YBD=1752 YHG=1717>have " XBD=460 XHG=360 YBD=1763 YHG=1717>kept " XBD=552 XHG=482 YBD=1752 YHG=1717>the " XBD=686 XHG=574 YBD=1752 YHG=1716>MRC " XBD=906 XHG=707 YBD=1751 YHG=1716>informed " XBD=972 XHG=927 YBD=1751 YHG=1716>of " XBD=1094 XHG=989 YBD=1752 YHG=1718>their " XBD=1302 XHG=1115 YBD=1762 YHG=1717>findings. " XBD=155 XHG=105 YBD=1801 YHG=1767>In " XBD=243 XHG=172 YBD=1801 YHG=1767>the " XBD=397 XHG=263 YBD=1802 YHG=1766>States " XBD=470 XHG=416 YBD=1801 YHG=1766>all " XBD=559 XHG=489 YBD=1801 YHG=1767>the " XBD=782 XHG=578 YBD=1812 YHG=1766>penicillin " XBD=917 XHG=799 YBD=1801 YHG=1766>made " XBD=969 XHG=936 YBD=1801 YHG=1767>is " XBD=1131 XHG=987 YBD=1811 YHG=1766>pooled " XBD=1232 XHG=1150 YBD=1801 YHG=1767>and " XBD=1304 XHG=1250 YBD=1801 YHG=1767>its " XBD=173 XHG=103 YBD=1851 YHG=1828>use " XBD=223 XHG=189 YBD=1850 YHG=1816>is " XBD=463 XHG=242 YBD=1851 YHG=1816>controlled " XBD=537 XHG=480 YBD=1861 YHG=1816>by " XBD=577 XHG=553 YBD=1851 YHG=1828>a " XBD=852 XHG=596 YBD=1858 YHG=1816>committee ; " XBD=957 XHG=886 YBD=1850 YHG=1816>the " XBD=1085 XHG=973 YBD=1851 YHG=1816>MRC " XBD=1135 XHG=1102 YBD=1850 YHG=1816>is " XBD=1304 XHG=1154 YBD=1862 YHG=1817>setting " XBD=159 XHG=103 YBD=1912 YHG=1878>up " XBD=205 XHG=181 YBD=1900 YHG=1878>a " XBD=378 XHG=228 YBD=1900 YHG=1865>similar " XBD=641 XHG=402 YBD=1910 YHG=1865>controlling " XBD=895 XHG=665 YBD=1900 YHG=1865>committee " XBD=1023 XHG=918 YBD=1900 YHG=1865>here. |>" XBD=138 XHG=132 YBD=1933 YHG=1928>’ " XBD=283 XHG=154 YBD=1951 YHG=1915>While " XBD=388 XHG=305 YBD=1950 YHG=1915>this " XBD=598 XHG=412 YBD=1960 YHG=1916>shortage " XBD=737 XHG=621 YBD=1949 YHG=1914>holds " XBD=1018 XHG=759 YBD=1960 YHG=1926>upprogress " XBD=1099 XHG=1040 YBD=1948 YHG=1926>we " XBD=1198 XHG=1123 YBD=1949 YHG=1926>can " XBD=1304 XHG=1221 YBD=1950 YHG=1915>still " XBD=207 XHG=102 YBD=2011 YHG=1965>hope " XBD=290 XHG=228 YBD=2000 YHG=1964>for " XBD=338 XHG=313 YBD=1999 YHG=1977>a " XBD=562 XHG=361 YBD=2000 YHG=1965>short-cut " XBD=629 XHG=586 YBD=1999 YHG=1976>or " XBD=677 XHG=652 YBD=1999 YHG=1975>a " XBD=904 XHG=701 YBD=1998 YHG=1963>collateral " XBD=1174 XHG=927 YBD=1999 YHG=1964>circulation. " XBD=1303 XHG=1229 YBD=2000 YHG=1964>We " XBD=155 XHG=103 YBD=2049 YHG=2026>no " XBD=309 XHG=172 YBD=2060 YHG=2014>longer " XBD=432 XHG=326 YBD=2049 YHG=2015>have " XBD=494 XHG=448 YBD=2049 YHG=2017>to " XBD=671 XHG=512 YBD=2059 YHG=2014>depend " XBD=742 XHG=688 YBD=2048 YHG=2025>on " XBD=1022 XHG=758 YBD=2048 YHG=2013>willow-trees " XBD=1101 XHG=1038 YBD=2048 YHG=2012>for " XBD=1191 XHG=1118 YBD=2048 YHG=2026>our " XBD=1301 XHG=1209 YBD=2059 YHG=2026>sup- " XBD=201 XHG=102 YBD=2110 YHG=2063>plies " XBD=264 XHG=219 YBD=2099 YHG=2063>of " XBD=519 XHG=279 YBD=2109 YHG=2063>salicylates, " XBD=584 XHG=540 YBD=2098 YHG=2075>so " XBD=696 XHG=602 YBD=2108 YHG=2063>why " XBD=823 XHG=713 YBD=2098 YHG=2066>must " XBD=899 XHG=841 YBD=2097 YHG=2074>we " XBD=1003 XHG=916 YBD=2108 YHG=2062>rely " XBD=1073 XHG=1020 YBD=2098 YHG=2075>on " XBD=1161 XHG=1091 YBD=2097 YHG=2064>the " XBD=1301 XHG=1179 YBD=2098 YHG=2063>much " XBD=212 XHG=103 YBD=2149 YHG=2125>more " XBD=459 XHG=237 YBD=2159 YHG=2113>capricious " XBD=736 XHG=483 YBD=2147 YHG=2113>Penicillium |>" XBD=932 XHG=760 YBD=2148 YHG=2117>notatitm " XBD=1018 XHG=955 YBD=2147 YHG=2112>for " XBD=1115 XHG=1042 YBD=2147 YHG=2124>our " XBD=1299 XHG=1139 YBD=2158 YHG=2112>penicil- lin . " XBD=571 XHG=250 YBD=2207 YHG=2162>Unfortunately " XBD=677 XHG=607 YBD=2196 YHG=2162>the " XBD=915 XHG=716 YBD=2207 YHG=2162>synthesis " XBD=998 XHG=953 YBD=2197 YHG=2161>of " XBD=1182 XHG=1031 YBD=2208 YHG=2162>aspirin " XBD=1301 XHG=1219 YBD=2198 YHG=2174>was " XBD=245 XHG=104 YBD=2259 YHG=2212>simple " XBD=478 XHG=263 YBD=2258 YHG=2212>compared " XBD=594 XHG=494 YBD=2246 YHG=2212>with " XBD=704 XHG=610 YBD=2246 YHG=2212>that " XBD=766 XHG=721 YBD=2246 YHG=2211>of " XBD=991 XHG=777 YBD=2257 YHG=2211>penicillin, " XBD=1080 XHG=1010 YBD=2246 YHG=2213>the " XBD=1300 XHG=1099 YBD=2246 YHG=2215>structure " XBD=149 XHG=104 YBD=2296 YHG=2260>of " XBD=305 XHG=176 YBD=2296 YHG=2261>which " XBD=371 XHG=337 YBD=2295 YHG=2262>is " XBD=501 XHG=404 YBD=2306 YHG=2260>only " XBD=622 XHG=531 YBD=2295 YHG=2272>now " XBD=869 XHG=652 YBD=2306 YHG=2261>beginning " XBD=944 XHG=899 YBD=2294 YHG=2264>to " XBD=1026 XHG=976 YBD=2295 YHG=2261>be " XBD=1297 XHG=1057 YBD=2295 YHG=2260>elucidated. " XBD=259 XHG=103 YBD=2355 YHG=2309>Lately, " XBD=436 XHG=282 YBD=2345 YHG=2310>Oxford workers " XBD=781 XHG=644 YBD=2344 YHG=2310>1 have " XBD=993 XHG=801 YBD=2345 YHG=2310>obtained " XBD=1036 XHG=1013 YBD=2344 YHG=2322>a " XBD=1301 XHG=1057 YBD=2345 YHG=2310>substantial " XBD=196 XHG=102 YBD=2405 YHG=2363>part " XBD=273 XHG=227 YBD=2394 YHG=2359>of " XBD=370 XHG=299 YBD=2394 YHG=2360>the " XBD=605 XHG=402 YBD=2405 YHG=2359>penicillin " XBD=829 XHG=636 YBD=2394 YHG=2359>molecule " XBD=898 XHG=855 YBD=2393 YHG=2360>in " XBD=1154 XHG=925 YBD=2405 YHG=2359>crystalline " XBD=1298 XHG=1181 YBD=2395 YHG=2358>form. " XBD=198 XHG=102 YBD=2443 YHG=2409>This " XBD=672 XHG=236 YBD=2454 YHG=2409>nitrogen-containing " XBD=953 XHG=712 YBD=2454 YHG=2409>compound, " XBD=1298 XHG=992 YBD=2454 YHG=2408>penicillamine, " XBD=307 XHG=104 YBD=2503 YHG=2458>produced " XBD=380 XHG=324 YBD=2502 YHG=2458>by " XBD=624 XHG=396 YBD=2503 YHG=2457>hydrolysis " XBD=686 XHG=642 YBD=2492 YHG=2457>of " XBD=912 XHG=699 YBD=2503 YHG=2457>penicillin, " XBD=1101 XHG=931 YBD=2503 YHG=2468>appears " XBD=1161 XHG=1117 YBD=2492 YHG=2460>to " XBD=1229 XHG=1179 YBD=2492 YHG=2458>be " XBD=1300 XHG=1246 YBD=2492 YHG=2469>an " XBD=359 XHG=101 YBD=2548 YHG=2507>amino-acid, " XBD=463 XHG=388 YBD=2541 YHG=2507>but " XBD=588 XHG=489 YBD=2541 YHG=2507>with " XBD=834 XHG=613 YBD=2553 YHG=2508>properties " XBD=958 XHG=860 YBD=2553 YHG=2519>very " XBD=1169 XHG=983 YBD=2542 YHG=2506>different " XBD=1299 XHG=1195 YBD=2541 YHG=2506>from " XBD=173 XHG=103 YBD=2589 YHG=2555>the " XBD=346 XHG=198 YBD=2590 YHG=2556>known " XBD=648 XHG=372 YBD=2597 YHG=2556>amino-acids, " XBD=905 XHG=676 YBD=2602 YHG=2557>suggesting " XBD=955 XHG=931 YBD=2591 YHG=2569>a " XBD=1150 XHG=980 YBD=2591 YHG=2555>relation " XBD=1221 XHG=1175 YBD=2591 YHG=2559>to " XBD=1300 XHG=1247 YBD=2590 YHG=2568>an " XBD=375 XHG=101 YBD=2649 YHG=2604>amino-sugar " XBD=482 XHG=400 YBD=2639 YHG=2605>and " XBD=683 XHG=506 YBD=2639 YHG=2605>ascorbic " XBD=810 XHG=708 YBD=2639 YHG=2606>acid. " XBD=1045 XHG=864 YBD=2640 YHG=2605>Another " XBD=1300 XHG=1070 YBD=2650 YHG=2605>crystalline " XBD=488 XHG=104 YBD=2698 YHG=2653>product-penillic " XBD=727 XHG=512 YBD=2688 YHG=2654>acid-has " XBD=852 XHG=746 YBD=2688 YHG=2654>since " XBD=975 XHG=873 YBD=2688 YHG=2654>been produced " XBD=1301 XHG=1211 YBD=2698 YHG=2654>2 by " XBD=195 XHG=101 YBD=2736 YHG=2701>acid " XBD=483 XHG=215 YBD=2736 YHG=2702>inactivation " XBD=551 XHG=506 YBD=2736 YHG=2702>of " XBD=782 XHG=569 YBD=2747 YHG=2702>penicillin, " XBD=884 XHG=803 YBD=2737 YHG=2703>and " XBD=984 XHG=902 YBD=2737 YHG=2703>this " XBD=1082 XHG=1003 YBD=2736 YHG=2702>will " XBD=1301 XHG=1102 YBD=2748 YHG=2702>probably " XBD=227 XHG=103 YBD=2795 YHG=2761>prove " XBD=294 XHG=250 YBD=2784 YHG=2753>to " XBD=369 XHG=319 YBD=2784 YHG=2750>be " XBD=418 XHG=393 YBD=2785 YHG=2762>a " XBD=569 XHG=440 YBD=2796 YHG=2750>larger " XBD=685 XHG=592 YBD=2796 YHG=2754>part " XBD=754 XHG=710 YBD=2786 YHG=2751>of " XBD=844 XHG=774 YBD=2786 YHG=2752>the " XBD=1069 XHG=867 YBD=2797 YHG=2751>penicillin " XBD=1298 XHG=1093 YBD=2787 YHG=2751>molecule. " XBD=229 XHG=99 YBD=2834 YHG=2800>These " XBD=328 XHG=261 YBD=2834 YHG=2810>are " XBD=547 XHG=359 YBD=2834 YHG=2798>valuable " XBD=688 XHG=579 YBD=2845 YHG=2803>steps " XBD=894 XHG=718 YBD=2836 YHG=2801>towards " XBD=994 XHG=924 YBD=2835 YHG=2801>the " XBD=1226 XHG=1025 YBD=2835 YHG=2801>short-cut " XBD=1303 XHG=1258 YBD=2834 YHG=2800>of " XBD=316 XHG=101 YBD=2893 YHG=2848>synthesis, " XBD=417 XHG=341 YBD=2882 YHG=2848>but " XBD=551 XHG=440 YBD=2893 YHG=2847>early " XBD=680 XHG=574 YBD=2884 YHG=2860>ones. " XBD=818 XHG=735 YBD=2883 YHG=2850>The " XBD=956 XHG=842 YBD=2884 YHG=2850>other " XBD=1128 XHG=980 YBD=2883 YHG=2850>chance " XBD=1184 XHG=1150 YBD=2883 YHG=2851>is " XBD=1300 XHG=1207 YBD=2884 YHG=2850>that " XBD=273 XHG=100 YBD=2931 YHG=2897>another " XBD=517 XHG=286 YBD=2942 YHG=2897>compound " XBD=608 XHG=529 YBD=2931 YHG=2897>will " XBD=670 XHG=620 YBD=2931 YHG=2898>be " XBD=810 XHG=682 YBD=2932 YHG=2898>found " XBD=950 XHG=821 YBD=2932 YHG=2899>which " XBD=1041 XHG=963 YBD=2932 YHG=2898>will " XBD=1101 XHG=1051 YBD=2932 YHG=2898>be " XBD=1154 XHG=1111 YBD=2932 YHG=2910>as " XBD=1298 XHG=1164 YBD=2942 YHG=2900>upset- " XBD=189 XHG=102 YBD=2991 YHG=2946>ting " XBD=254 XHG=208 YBD=2991 YHG=2948>to " XBD=469 XHG=274 YBD=2979 YHG=2945>bacterial " XBD=745 XHG=489 YBD=2981 YHG=2937>metabolism " XBD=809 XHG=765 YBD=2980 YHG=2958>as " XBD=1033 XHG=829 YBD=2992 YHG=2946>penicillin " XBD=1129 XHG=1054 YBD=2981 YHG=2947>but " XBD=1230 XHG=1149 YBD=2980 YHG=2946>will " XBD=1300 XHG=1250 YBD=2980 YHG=2946>be " XBD=229 XHG=100 YBD=3040 YHG=2994>.easily " XBD=380 XHG=249 YBD=3030 YHG=2994>made. " XBD=517 XHG=435 YBD=3028 YHG=2994>Yet " XBD=621 XHG=539 YBD=3031 YHG=2994>this " XBD=772 XHG=642 YBD=3040 YHG=2996>might " XBD=912 XHG=794 YBD=3030 YHG=3006>mean " XBD=1003 XHG=933 YBD=3029 YHG=2995>the " XBD=1104 XHG=1024 YBD=3030 YHG=2994>loss " XBD=1172 XHG=1127 YBD=3029 YHG=2994>of " XBD=1300 XHG=1189 YBD=3030 YHG=2996>what " XBD=233 XHG=104 YBD=3090 YHG=3044>might " XBD=302 XHG=253 YBD=3078 YHG=3044>be " XBD=347 XHG=322 YBD=3078 YHG=3055>a " XBD=547 XHG=365 YBD=3088 YHG=3043>triumph " XBD=628 XHG=565 YBD=3078 YHG=3042>for " XBD=798 XHG=647 YBD=3078 YHG=3044>British " XBD=1146 XHG=817 YBD=3090 YHG=3044>bacteriologists, " XBD=1298 XHG=1168 YBD=3078 YHG=3044>chem- " XBD=190 XHG=99 YBD=3134 YHG=3093>ists, " XBD=314 XHG=213 YBD=3138 YHG=3093>drug " XBD=656 XHG=335 YBD=3127 YHG=3092>manufacturers " XBD=760 XHG=678 YBD=3127 YHG=3092>and " XBD=996 XHG=781 YBD=3127 YHG=3092>clinicians. " XBD=1298 XHG=1050 YBD=3134 YHG=3092>Meanwhile, " XBD=288 XHG=104 YBD=3176 YHG=3142>however " XBD=429 XHG=306 YBD=3175 YHG=3141>much " XBD=507 XHG=447 YBD=3175 YHG=3152>we " XBD=659 XHG=526 YBD=3175 YHG=3141>would " XBD=758 XHG=677 YBD=3175 YHG=3141>like " XBD=801 XHG=777 YBD=3174 YHG=3152>a " XBD=895 XHG=819 YBD=3187 YHG=3140>few " XBD=1111 XHG=913 YBD=3186 YHG=3152>grammes " XBD=1175 XHG=1130 YBD=3176 YHG=3141>of " XBD=1299 XHG=1189 YBD=3186 YHG=3141>peni- |>" XBD=212 XHG=101 YBD=3233 YHG=3190>cillin " XBD=286 XHG=223 YBD=3224 YHG=3189>for " XBD=352 XHG=298 YBD=3224 YHG=3201>an " XBD=591 XHG=364 YBD=3224 YHG=3188>individual " XBD=772 XHG=602 YBD=3234 YHG=3189>patient, " XBD=819 XHG=786 YBD=3222 YHG=3189>it " XBD=865 XHG=831 YBD=3223 YHG=3183>is " XBD=984 XHG=877 YBD=3234 YHG=3190>right " XBD=1089 XHG=996 YBD=3224 YHG=3191>that " XBD=1172 XHG=1102 YBD=3224 YHG=3190>the " XBD=1302 XHG=1185 YBD=3224 YHG=3188>small " XBD=274 XHG=100 YBD=3273 YHG=3242>amount " XBD=415 XHG=294 YBD=3273 YHG=3239>made " XBD=581 XHG=436 YBD=3273 YHG=3238>should " XBD=652 XHG=602 YBD=3282 YHG=3249>go " XBD=719 XHG=673 YBD=3271 YHG=3240>to " XBD=810 XHG=740 YBD=3272 YHG=3238>the " XBD=1022 XHG=834 YBD=3272 YHG=3238>chemists " XBD=1104 XHG=1042 YBD=3272 YHG=3237>for " XBD=1301 XHG=1126 YBD=3282 YHG=3238>analysis " XBD=149 XHG=99 YBD=3322 YHG=3299>or " XBD=224 XHG=174 YBD=3322 YHG=3287>be " XBD=395 XHG=250 YBD=3332 YHG=3287>pooled " XBD=503 XHG=421 YBD=3321 YHG=3287>and " XBD=628 XHG=528 YBD=3321 YHG=3286>used " XBD=696 XHG=652 YBD=3320 YHG=3286>in " XBD=914 XHG=722 YBD=3331 YHG=3284>carefully " XBD=1114 XHG=939 YBD=3331 YHG=3285>planned " XBD=1296 XHG=1141 YBD=3321 YHG=3286>clinical " XBD=215 XHG=98 YBD=3370 YHG=3335>trials " XBD=358 XHG=231 YBD=3370 YHG=3336>under " XBD=443 XHG=373 YBD=3370 YHG=3336>the " XBD=533 XHG=460 YBD=3380 YHG=3347>eye " XBD=594 XHG=549 YBD=3371 YHG=3335>of " XBD=631 XHG=606 YBD=3370 YHG=3347>a " XBD=759 XHG=646 YBD=3370 YHG=3334>MRC " XBD=1016 XHG=776 YBD=3369 YHG=3335>committee. 1. Abraham, E. P., Chain, E., Baker, W. and Robinson, R. Nature, Lond. Jan. 23, 1943; p. 107. 2. Duffin, W. M. and Smith, S. Ibid, Feb. 27, 1943, p. 251. PHYSICAL APPROACH TO THE BRAIN " XBD=1469 XHG=1416 YBD=326 YHG=291>IN " XBD=1575 XHG=1504 YBD=326 YHG=291>the " XBD=1702 XHG=1608 YBD=326 YHG=290>field " XBD=1782 XHG=1740 YBD=326 YHG=291>of " XBD=1969 XHG=1817 YBD=325 YHG=290>mental " XBD=2182 XHG=2002 YBD=325 YHG=290>disorder " XBD=2356 XHG=2216 YBD=324 YHG=289>failure " XBD=2425 XHG=2384 YBD=324 YHG=293>to " XBD=2527 XHG=2455 YBD=335 YHG=290>plan " XBD=1619 XHG=1365 YBD=385 YHG=340>therapeutic " XBD=1905 XHG=1637 YBD=385 YHG=330>experiments " XBD=2000 XHG=1926 YBD=374 YHG=339>has " XBD=2090 XHG=2024 YBD=373 YHG=338>led " XBD=2163 XHG=2118 YBD=373 YHG=342>to " XBD=2312 XHG=2192 YBD=374 YHG=338>much " XBD=2526 XHG=2341 YBD=374 YHG=337>confusion. " XBD=1534 XHG=1365 YBD=429 YHG=388>Insulin, " XBD=1753 XHG=1567 YBD=434 YHG=385>leptazol, " XBD=1985 XHG=1788 YBD=422 YHG=387>electrical " XBD=2285 XHG=2020 YBD=428 YHG=388>convulsions, " XBD=2398 XHG=2319 YBD=421 YHG=387>and " XBD=2526 XHG=2425 YBD=421 YHG=386>leuco. " XBD=1483 XHG=1364 YBD=482 YHG=440>tomy " XBD=1602 XHG=1498 YBD=471 YHG=437>have " XBD=1730 XHG=1619 YBD=471 YHG=448>come " XBD=1799 XHG=1746 YBD=471 YHG=448>on " XBD=1884 XHG=1814 YBD=471 YHG=436>the " XBD=2012 XHG=1900 YBD=481 YHG=440>stage " XBD=2070 XHG=2028 YBD=470 YHG=437>in " XBD=2194 XHG=2085 YBD=477 YHG=440>turn, " XBD=2287 XHG=2213 YBD=470 YHG=436>but " XBD=2410 XHG=2302 YBD=469 YHG=436>there " XBD=2454 XHG=2424 YBD=468 YHG=435>is " XBD=2528 XHG=2467 YBD=470 YHG=435>still " XBD=1628 XHG=1366 YBD=530 YHG=488>controversy " XBD=1779 XHG=1652 YBD=520 YHG=486>about " XBD=1907 XHG=1803 YBD=519 YHG=486>their " XBD=2096 XHG=1932 YBD=529 YHG=485>efficacy " XBD=2202 XHG=2120 YBD=519 YHG=485>and " XBD=2295 XHG=2226 YBD=518 YHG=484>the " XBD=2527 XHG=2319 YBD=518 YHG=483>indications " XBD=1427 XHG=1364 YBD=569 YHG=533>for " XBD=1559 XHG=1454 YBD=569 YHG=534>their " XBD=1668 XHG=1587 YBD=569 YHG=546>use. " XBD=1821 XHG=1740 YBD=569 YHG=534>Yet " XBD=1907 XHG=1856 YBD=568 YHG=534>R. " XBD=1987 XHG=1940 YBD=568 YHG=533>A. |>" XBD=2209 XHG=2011 YBD=568 YHG=533>FisHER’s " XBD=2347 XHG=2242 YBD=567 YHG=533>book " XBD=2408 XHG=2376 YBD=566 YHG=532>is " XBD=2528 XHG=2435 YBD=578 YHG=531>fairly " XBD=1512 XHG=1365 YBD=628 YHG=583>widely " XBD=1635 XHG=1538 YBD=617 YHG=583>read " XBD=1809 XHG=1663 YBD=628 YHG=595>among " XBD=1997 XHG=1837 YBD=618 YHG=583>doctors " XBD=2108 XHG=2026 YBD=617 YHG=583>and " XBD=2357 XHG=2139 YBD=627 YHG=580>biologists, " XBD=2455 XHG=2382 YBD=615 YHG=580>and " XBD=2526 XHG=2479 YBD=616 YHG=570>ex. " XBD=1547 XHG=1365 YBD=676 YHG=631>perience " XBD=1617 XHG=1572 YBD=666 YHG=634>at " XBD=1914 XHG=1643 YBD=666 YHG=632>Rothamsted " XBD=2082 XHG=1939 YBD=666 YHG=631>should " XBD=2219 XHG=2107 YBD=665 YHG=642>serve " XBD=2287 XHG=2244 YBD=664 YHG=642>as " XBD=2339 XHG=2315 YBD=664 YHG=642>a " XBD=2528 XHG=2361 YBD=665 YHG=629>reminder " XBD=1460 XHG=1365 YBD=714 YHG=680>that " XBD=1709 XHG=1499 YBD=724 YHG=679>biological " XBD=2021 XHG=1753 YBD=725 YHG=680>experiments " XBD=2166 XHG=2064 YBD=714 YHG=680>need " XBD=2253 XHG=2209 YBD=713 YHG=682>to " XBD=2338 XHG=2289 YBD=713 YHG=679>be " XBD=2526 XHG=2369 YBD=723 YHG=678>planned. " XBD=1531 XHG=1366 YBD=762 YHG=728>LIONEL " XBD=1787 XHG=1557 YBD=770 YHG=729>PENROSE,1 " XBD=2028 XHG=1814 YBD=773 YHG=728>surveying " XBD=2151 XHG=2054 YBD=762 YHG=728>with " XBD=2204 XHG=2180 YBD=762 YHG=740>a " XBD=2399 XHG=2231 YBD=762 YHG=726>suitable " XBD=2527 XHG=2420 YBD=762 YHG=728>statis. " XBD=1463 XHG=1365 YBD=811 YHG=776>tical " XBD=1714 XHG=1499 YBD=823 YHG=777>technique " XBD=1820 XHG=1750 YBD=812 YHG=778>the " XBD=1957 XHG=1860 YBD=812 YHG=778>1600 " XBD=2172 XHG=1993 YBD=822 YHG=777>patients " XBD=2297 XHG=2209 YBD=811 YHG=776>who " XBD=2417 XHG=2340 YBD=811 YHG=776>had " XBD=2528 XHG=2451 YBD=812 YHG=776>been " XBD=1682 XHG=1366 YBD=872 YHG=826>given &dquo;shock " XBD=1970 XHG=1709 YBD=861 YHG=825>treatment &dquo; " XBD=2051 XHG=2007 YBD=860 YHG=827>in " XBD=2157 XHG=2087 YBD=860 YHG=826>the " XBD=2337 XHG=2186 YBD=860 YHG=825>mental " XBD=2529 XHG=2364 YBD=871 YHG=825>hospitals " XBD=1412 XHG=1366 YBD=910 YHG=874>of " XBD=1778 XHG=1428 YBD=910 YHG=875>Ontario-which " XBD=1900 XHG=1796 YBD=909 YHG=876>have " XBD=1968 XHG=1915 YBD=909 YHG=887>an " XBD=2150 XHG=1982 YBD=920 YHG=886>average " XBD=2212 XHG=2166 YBD=909 YHG=874>of " XBD=2371 XHG=2229 YBD=916 YHG=876>16,000, " XBD=2528 XHG=2381 YBD=920 YHG=875>patients " XBD=1408 XHG=1365 YBD=958 YHG=924>in " XBD=1903 XHG=1437 YBD=964 YHG=924>residence-concludes " XBD=2086 XHG=1931 YBD=958 YHG=923>that &dquo; " XBD=2245 XHG=2104 YBD=971 YHG=924>taking " XBD=2331 XHG=2277 YBD=957 YHG=923>all " XBD=2423 XHG=2357 YBD=957 YHG=924>the " XBD=2545 XHG=2449 YBD=960 YHG=922>facts’ " XBD=1564 XHG=1366 YBD=1018 YHG=973>together, " XBD=1779 XHG=1584 YBD=1014 YHG=973>however, " XBD=1847 XHG=1798 YBD=1007 YHG=961>it " XBD=1889 XHG=1855 YBD=1007 YHG=973>is " XBD=2121 XHG=1913 YBD=1019 YHG=960>probably " XBD=2214 XHG=2130 YBD=1007 YHG=972>safe " XBD=2275 XHG=2231 YBD=1007 YHG=976>to " XBD=2443 XHG=2294 YBD=1007 YHG=983>assume " XBD=2529 XHG=2458 YBD=1009 YHG=973>that " XBD=1408 XHG=1366 YBD=1056 YHG=1023>in " XBD=1709 XHG=1438 YBD=1067 YHG=1034>consequence " XBD=1782 XHG=1737 YBD=1057 YHG=1021>of " XBD=1879 XHG=1808 YBD=1056 YHG=1022>the " XBD=2034 XHG=1910 YBD=1057 YHG=1022>shock " XBD=2238 XHG=2064 YBD=1067 YHG=1022>therapy " XBD=2376 XHG=2269 YBD=1056 YHG=1022>work " XBD=2530 XHG=2407 YBD=1059 YHG=1022>carried " XBD=1441 XHG=1367 YBD=1107 YHG=1074>out " XBD=1605 XHG=1460 YBD=1117 YHG=1071>during " XBD=1694 XHG=1624 YBD=1105 YHG=1072>the " XBD=1830 XHG=1715 YBD=1116 YHG=1082>years " XBD=2024 XHG=1853 YBD=1106 YHG=1072>1938-41 " XBD=2160 XHG=2045 YBD=1105 YHG=1071>there " XBD=2281 XHG=2181 YBD=1105 YHG=1082>were " XBD=2344 XHG=2300 YBD=1105 YHG=1074>at " XBD=2456 XHG=2363 YBD=1106 YHG=1070>least " XBD=2529 XHG=2476 YBD=1108 YHG=1073>100 " XBD=1547 XHG=1367 YBD=1166 YHG=1121>patients " XBD=1686 XHG=1568 YBD=1155 YHG=1120>fewer " XBD=1761 XHG=1708 YBD=1155 YHG=1132>on " XBD=1852 XHG=1781 YBD=1157 YHG=1121>the " XBD=1999 XHG=1873 YBD=1155 YHG=1120>books " XBD=2066 XHG=2022 YBD=1154 YHG=1119>of " XBD=2154 XHG=2084 YBD=1154 YHG=1120>the " XBD=2344 XHG=2177 YBD=1156 YHG=1120>Ontario " XBD=2529 XHG=2363 YBD=1167 YHG=1120>hospitals " XBD=1513 XHG=1367 YBD=1217 YHG=1170>during " XBD=1602 XHG=1532 YBD=1204 YHG=1169>the " XBD=1717 XHG=1622 YBD=1215 YHG=1181>year " XBD=1912 XHG=1739 YBD=1204 YHG=1170>1941-42 " XBD=2035 XHG=1932 YBD=1204 YHG=1169>than " XBD=2166 XHG=2052 YBD=1204 YHG=1169>there " XBD=2318 XHG=2186 YBD=1204 YHG=1170>would " XBD=2435 XHG=2336 YBD=1204 YHG=1170>have " XBD=2531 XHG=2453 YBD=1206 YHG=1170>been " XBD=1405 XHG=1366 YBD=1253 YHG=1214>if " XBD=1477 XHG=1423 YBD=1254 YHG=1230>no " XBD=1601 XHG=1503 YBD=1253 YHG=1219>such " XBD=1783 XHG=1626 YBD=1264 YHG=1218>specific " XBD=2029 XHG=1807 YBD=1253 YHG=1221>treatment " XBD=2135 XHG=2052 YBD=1254 YHG=1219>had " XBD=2260 XHG=2160 YBD=1253 YHG=1218>been " XBD=2438 XHG=2285 YBD=1265 YHG=1218>given.&dquo; " XBD=2530 XHG=2484 YBD=1255 YHG=1220>He " XBD=1454 XHG=1369 YBD=1303 YHG=1268>also " XBD=1598 XHG=1469 YBD=1303 YHG=1267>found " XBD=1705 XHG=1612 YBD=1302 YHG=1269>that " XBD=1907 XHG=1721 YBD=1302 YHG=1267>valuable " XBD=1967 XHG=1922 YBD=1302 YHG=1279>as " XBD=2052 XHG=1982 YBD=1302 YHG=1268>the " XBD=2235 XHG=2067 YBD=1302 YHG=1268>method " XBD=2283 XHG=2249 YBD=1301 YHG=1268>is " XBD=2362 XHG=2297 YBD=1303 YHG=1260>for " XBD=2530 XHG=2374 YBD=1304 YHG=1268>affective " XBD=1584 XHG=1368 YBD=1363 YHG=1318>psychoses " XBD=1646 XHG=1604 YBD=1352 YHG=1318>in " XBD=1830 XHG=1666 YBD=1363 YHG=1328>persons " XBD=1937 XHG=1850 YBD=1351 YHG=1317>first " XBD=2158 XHG=1958 YBD=1351 YHG=1317>admitted " XBD=2357 XHG=2179 YBD=1352 YHG=1318>between " XBD=2441 XHG=2376 YBD=1352 YHG=1318>the " XBD=2530 XHG=2459 YBD=1363 YHG=1312>ages " XBD=1414 XHG=1368 YBD=1401 YHG=1366>of " XBD=1483 XHG=1432 YBD=1401 YHG=1368>40 " XBD=1586 XHG=1506 YBD=1401 YHG=1367>and " XBD=1657 XHG=1609 YBD=1402 YHG=1368>59 " XBD=1807 XHG=1680 YBD=1412 YHG=1378>years, " XBD=1855 XHG=1833 YBD=1379 YHG=1365>&dquo; " XBD=1973 XHG=1874 YBD=1411 YHG=1377>very " XBD=2099 XHG=1992 YBD=1400 YHG=1365>little " XBD=2289 XHG=2121 YBD=1411 YHG=1369>support " XBD=2344 XHG=2311 YBD=1401 YHG=1367>is " XBD=2531 XHG=2365 YBD=1412 YHG=1367>provided " XBD=1430 XHG=1367 YBD=1451 YHG=1415>for " XBD=1522 XHG=1451 YBD=1450 YHG=1416>the " XBD=1656 XHG=1543 YBD=1457 YHG=1417>view, " XBD=1869 XHG=1678 YBD=1460 YHG=1415>formerly " XBD=2032 XHG=1888 YBD=1460 YHG=1415>widely " XBD=2157 XHG=2051 YBD=1455 YHG=1415>held, " XBD=2273 XHG=2180 YBD=1450 YHG=1415>that " XBD=2415 XHG=2294 YBD=1450 YHG=1416>shock " XBD=2529 XHG=2432 YBD=1452 YHG=1419>treat- " XBD=1482 XHG=1367 YBD=1500 YHG=1468>ment " XBD=1578 XHG=1506 YBD=1499 YHG=1466>has " XBD=1721 XHG=1603 YBD=1499 YHG=1464>value " XBD=1788 XHG=1744 YBD=1499 YHG=1466>in " XBD=2150 XHG=1812 YBD=1510 YHG=1464>schizophrenia.&dquo; " XBD=2331 XHG=2206 YBD=1499 YHG=1464>These " XBD=2531 XHG=2355 YBD=1500 YHG=1466>moderate " XBD=1618 XHG=1368 YBD=1549 YHG=1513>conclusions " XBD=1705 XHG=1639 YBD=1548 YHG=1525>are " XBD=1767 XHG=1725 YBD=1549 YHG=1514>in " XBD=1907 XHG=1788 YBD=1560 YHG=1514>sharp " XBD=2109 XHG=1929 YBD=1549 YHG=1516>contrast " XBD=2227 XHG=2128 YBD=1548 YHG=1514>with " XBD=2321 XHG=2251 YBD=1548 YHG=1514>the " XBD=2531 XHG=2342 YBD=1560 YHG=1514>optimistic " XBD=1609 XHG=1368 YBD=1598 YHG=1566>statements " XBD=1738 XHG=1622 YBD=1598 YHG=1563>made " XBD=1878 XHG=1751 YBD=1598 YHG=1563>about " XBD=1961 XHG=1891 YBD=1597 YHG=1563>the " XBD=2139 XHG=1974 YBD=1608 YHG=1562>efficacy " XBD=2199 XHG=2154 YBD=1597 YHG=1562>of " XBD=2357 XHG=2210 YBD=1597 YHG=1563>insulin " XBD=2447 XHG=2370 YBD=1598 YHG=1564>and " XBD=2529 XHG=2460 YBD=1598 YHG=1575>con. " XBD=1528 XHG=1367 YBD=1647 YHG=1612>vulsion " XBD=1726 XHG=1541 YBD=1658 YHG=1612>therapy. " XBD=1831 XHG=1781 YBD=1647 YHG=1613>In " XBD=1926 XHG=1845 YBD=1657 YHG=1624>any " XBD=2029 XHG=1941 YBD=1646 YHG=1623>case " XBD=2081 XHG=2047 YBD=1647 YHG=1613>it " XBD=2212 XHG=2099 YBD=1647 YHG=1612>looks " XBD=2275 XHG=2232 YBD=1646 YHG=1623>as " XBD=2328 XHG=2293 YBD=1646 YHG=1611>if " XBD=2367 XHG=2344 YBD=1647 YHG=1625>a " XBD=2531 XHG=2384 YBD=1657 YHG=1612>planned " XBD=1621 XHG=1366 YBD=1707 YHG=1662>therapeutic " XBD=1885 XHG=1635 YBD=1707 YHG=1662>experiment " XBD=2031 XHG=1898 YBD=1696 YHG=1661>would " XBD=2153 XHG=2048 YBD=1696 YHG=1662>have " XBD=2283 XHG=2166 YBD=1697 YHG=1662>made " XBD=2322 XHG=2299 YBD=1697 YHG=1674>a " XBD=2463 XHG=2337 YBD=1697 YHG=1662>better " XBD=2529 XHG=2478 YBD=1706 YHG=1662>job " XBD=1413 XHG=1367 YBD=1745 YHG=1710>of " XBD=1482 XHG=1437 YBD=1745 YHG=1711>it. " XBD=1715 XHG=1537 YBD=1756 YHG=1711>Perhaps " XBD=1812 XHG=1742 YBD=1745 YHG=1711>the " XBD=2091 XHG=1839 YBD=1757 YHG=1712>therapeutic " XBD=2232 XHG=2118 YBD=1745 YHG=1711>trials " XBD=2479 XHG=2260 YBD=1746 YHG=1710>committee " XBD=2533 XHG=2501 YBD=1746 YHG=1711>of " XBD=1438 XHG=1366 YBD=1794 YHG=1760>the " XBD=1627 XHG=1456 YBD=1794 YHG=1759>Medical " XBD=1846 XHG=1645 YBD=1794 YHG=1760>Research " XBD=2030 XHG=1866 YBD=1795 YHG=1760>Council " XBD=2179 XHG=2048 YBD=1806 YHG=1760>might " XBD=2247 XHG=2197 YBD=1795 YHG=1760>be " XBD=2450 XHG=2269 YBD=1796 YHG=1760>invoked. " XBD=1474 XHG=1417 YBD=1844 YHG=1809>At " XBD=1565 XHG=1495 YBD=1844 YHG=1810>the " XBD=1719 XHG=1587 YBD=1855 YHG=1809>Royal " XBD=2214 XHG=1739 YBD=1856 YHG=1809>Medico-Psychological " XBD=2477 XHG=2235 YBD=1844 YHG=1808>Association " XBD=2530 XHG=2493 YBD=1844 YHG=1821>on " XBD=1505 XHG=1365 YBD=1893 YHG=1859>March " XBD=1576 XHG=1530 YBD=1894 YHG=1861>10 " XBD=1668 XHG=1598 YBD=1893 YHG=1859>the " XBD=1850 XHG=1689 YBD=1905 YHG=1863>present " XBD=2005 XHG=1873 YBD=1894 YHG=1862>status " XBD=2071 XHG=2026 YBD=1893 YHG=1858>of " XBD=2310 XHG=2089 YBD=1905 YHG=1858>prefrontal " XBD=2531 XHG=2331 YBD=1904 YHG=1858>leucotomy " XBD=1447 XHG=1365 YBD=1943 YHG=1919>was " XBD=1688 XHG=1472 YBD=1943 YHG=1908>discussed. " XBD=1901 XHG=1743 YBD=1954 YHG=1908>Among " XBD=1995 XHG=1924 YBD=1943 YHG=1909>the " XBD=2299 XHG=2018 YBD=1955 YHG=1909>psychiatrists " XBD=2431 XHG=2322 YBD=1943 YHG=1909>there " XBD=2530 XHG=2452 YBD=1942 YHG=1919>were " XBD=1600 XHG=1366 YBD=1992 YHG=1958>differences " XBD=1679 XHG=1634 YBD=1992 YHG=1957>of " XBD=1873 XHG=1708 YBD=2004 YHG=1958>opinion " XBD=2032 XHG=1905 YBD=1993 YHG=1958>about " XBD=2119 XHG=2064 YBD=1993 YHG=1959>its " XBD=2270 XHG=2151 YBD=1992 YHG=1957>value " XBD=2394 XHG=2303 YBD=1993 YHG=1958>and’ " XBD=2531 XHG=2414 YBD=1992 YHG=1957>modus " XBD=1586 XHG=1366 YBD=2053 YHG=2008>operandi ; " XBD=1773 XHG=1627 YBD=2053 YHG=2019>among " XBD=1867 XHG=1796 YBD=2042 YHG=2008>the " XBD=2079 XHG=1891 YBD=2053 YHG=2019>surgeons " XBD=2230 XHG=2104 YBD=2043 YHG=2008>about " XBD=2323 XHG=2252 YBD=2042 YHG=2007>the " XBD=2531 XHG=2345 YBD=2052 YHG=2007>technique " XBD=1449 XHG=1366 YBD=2091 YHG=2057>and " XBD=1539 XHG=1468 YBD=2091 YHG=2057>the " XBD=1673 XHG=1559 YBD=2091 YHG=2057>risks. " XBD=1812 XHG=1728 YBD=2092 YHG=2058>But " XBD=1945 XHG=1832 YBD=2092 YHG=2058>there " XBD=2046 XHG=1965 YBD=2092 YHG=2068>was " XBD=2311 XHG=2067 YBD=2092 YHG=2056>substantial " XBD=2531 XHG=2332 YBD=2102 YHG=2058>agreement " XBD=1459 XHG=1365 YBD=2142 YHG=2107>that " XBD=1554 XHG=1484 YBD=2140 YHG=2107>the " XBD=1745 XHG=1579 YBD=2142 YHG=2107>method " XBD=1803 XHG=1769 YBD=2141 YHG=2107>is " XBD=1909 XHG=1828 YBD=2141 YHG=2106>still " XBD=2236 XHG=1934 YBD=2153 YHG=2106>experimental, " XBD=2353 XHG=2260 YBD=2141 YHG=2107>that " XBD=2408 XHG=2376 YBD=2141 YHG=2106>it " XBD=2531 XHG=2431 YBD=2140 YHG=2117>some- " XBD=1484 XHG=1364 YBD=2191 YHG=2156>times " XBD=1707 XHG=1512 YBD=2202 YHG=2156>produces " XBD=1934 XHG=1736 YBD=2191 YHG=2156>dramatic " XBD=2270 XHG=1962 YBD=2202 YHG=2157>improvement, " XBD=2391 XHG=2299 YBD=2190 YHG=2156>that " XBD=2456 XHG=2417 YBD=2190 YHG=2155>in " XBD=2532 XHG=2479 YBD=2190 YHG=2155>the " XBD=1495 XHG=1364 YBD=2240 YHG=2206>hands " XBD=1552 XHG=1508 YBD=2240 YHG=2205>of " XBD=1582 XHG=1558 YBD=2240 YHG=2218>a " XBD=1733 XHG=1593 YBD=2240 YHG=2205>skilled " XBD=2010 XHG=1742 YBD=2251 YHG=2205>neurological " XBD=2191 XHG=2020 YBD=2251 YHG=2218>surgeon " XBD=2232 XHG=2199 YBD=2240 YHG=2206>it " XBD=2274 XHG=2241 YBD=2240 YHG=2206>is " XBD=2355 XHG=2283 YBD=2239 YHG=2208>not " XBD=2531 XHG=2364 YBD=2240 YHG=2202>attended " XBD=1463 XHG=1363 YBD=2289 YHG=2255>with " XBD=1602 XHG=1489 YBD=2300 YHG=2258>great " XBD=1709 XHG=1626 YBD=2289 YHG=2255>risk " XBD=1777 XHG=1733 YBD=2289 YHG=2257>to " XBD=1883 XHG=1803 YBD=2296 YHG=2254>life, " XBD=1992 XHG=1910 YBD=2291 YHG=2255>and " XBD=2109 XHG=2016 YBD=2289 YHG=2255>that " XBD=2168 XHG=2133 YBD=2289 YHG=2255>it " XBD=2271 XHG=2197 YBD=2290 YHG=2266>can " XBD=2397 XHG=2295 YBD=2288 YHG=2254>have " XBD=2471 XHG=2420 YBD=2300 YHG=2254>by " XBD=2529 XHG=2491 YBD=2288 YHG=2264>no " XBD=1503 XHG=1363 YBD=2339 YHG=2315>means " XBD=1738 XHG=1527 YBD=2349 YHG=2303>negligible " XBD=1798 XHG=1755 YBD=2338 YHG=2303>ill " XBD=1973 XHG=1823 YBD=2338 YHG=2304>effects. " XBD=2098 XHG=2027 YBD=2339 YHG=2304>Dr. " XBD=2237 XHG=2119 YBD=2338 YHG=2305>ROLF " XBD=2531 XHG=2259 YBD=2339 YHG=2302>STROM-OLSE1 " XBD=1466 XHG=1363 YBD=2399 YHG=2364>gave " XBD=1509 XHG=1485 YBD=2388 YHG=2365>a " XBD=1675 XHG=1529 YBD=2388 YHG=2354>candid " XBD=1866 XHG=1694 YBD=2388 YHG=2356>account " XBD=1930 XHG=1886 YBD=2388 YHG=2352>of " XBD=2103 XHG=1947 YBD=2388 YHG=2353>clinical " XBD=2294 XHG=2122 YBD=2399 YHG=2353>findings " XBD=2436 XHG=2313 YBD=2387 YHG=2352>which " XBD=2531 XHG=2452 YBD=2387 YHG=2361>were " XBD=1437 XHG=1362 YBD=2437 YHG=2406>not " XBD=1692 XHG=1468 YBD=2447 YHG=2403>reassuring " XBD=1768 XHG=1724 YBD=2437 YHG=2414>as " XBD=1843 XHG=1799 YBD=2437 YHG=2406>to " XBD=1945 XHG=1875 YBD=2437 YHG=2403>the " XBD=2078 XHG=1976 YBD=2437 YHG=2403>wide " XBD=2386 XHG=2109 YBD=2449 YHG=2401>applicability " XBD=2456 XHG=2416 YBD=2436 YHG=2401>of " XBD=2531 XHG=2479 YBD=2435 YHG=2401>the " XBD=1542 XHG=1362 YBD=2486 YHG=2452>method. " XBD=1670 XHG=1596 YBD=2485 YHG=2452>Mr. " XBD=1758 XHG=1713 YBD=2486 YHG=2452>F. " XBD=1863 XHG=1801 YBD=2486 YHG=2452>W. " XBD=2122 XHG=1906 YBD=2487 YHG=2452>WILLWAY " XBD=2247 XHG=2165 YBD=2486 YHG=2451>and " XBD=2365 XHG=2292 YBD=2485 YHG=2450>Mr. " XBD=2530 XHG=2406 YBD=2486 YHG=2451>WrYLIE " XBD=1621 XHG=1361 YBD=2535 YHG=2501>McKISSOCK " XBD=1855 XHG=1647 YBD=2535 YHG=2501>described " XBD=1984 XHG=1880 YBD=2535 YHG=2501>their " XBD=2232 XHG=2009 YBD=2546 YHG=2502>respective " XBD=2422 XHG=2258 YBD=2546 YHG=2500>surgical |>" XBD=2529 XHG=2444 YBD=2535 YHG=2499>tech. " XBD=1518 XHG=1362 YBD=2596 YHG=2551>niques, " XBD=1616 XHG=1535 YBD=2584 YHG=2550>and " XBD=1704 XHG=1630 YBD=2585 YHG=2550>Mr. " XBD=1978 XHG=1720 YBD=2585 YHG=2550>McKISSOCK " XBD=2161 XHG=1992 YBD=2595 YHG=2551>pointed " XBD=2247 XHG=2175 YBD=2585 YHG=2553>out " XBD=2353 XHG=2261 YBD=2584 YHG=2550>that " XBD=2528 XHG=2368 YBD=2595 YHG=2549>epilepsy, " XBD=1531 XHG=1362 YBD=2644 YHG=2600>aphasia " XBD=1631 XHG=1549 YBD=2633 YHG=2600>and " XBD=1927 XHG=1649 YBD=2633 YHG=2599>incontinence " XBD=1990 XHG=1947 YBD=2633 YHG=2599>of " XBD=2119 XHG=2005 YBD=2633 YHG=2600>urine " XBD=2240 XHG=2138 YBD=2633 YHG=2611>were " XBD=2529 XHG=2259 YBD=2644 YHG=2598>complications " XBD=1457 XHG=1362 YBD=2682 YHG=2649>that " XBD=1597 XHG=1479 YBD=2682 YHG=2647>could " XBD=1689 XHG=1617 YBD=2682 YHG=2651>not " XBD=1760 XHG=1711 YBD=2683 YHG=2649>be " XBD=1990 XHG=1781 YBD=2682 YHG=2648>dismissed " XBD=2055 XHG=2011 YBD=2682 YHG=2659>as " XBD=2228 XHG=2076 YBD=2693 YHG=2648>trifling " XBD=2290 XHG=2247 YBD=2681 YHG=2649>in " XBD=2529 XHG=2310 YBD=2693 YHG=2648>comparison " XBD=1462 XHG=1363 YBD=2731 YHG=2697>with " XBD=1560 XHG=1490 YBD=2731 YHG=2697>the " XBD=1740 XHG=1587 YBD=2732 YHG=2697>mental " XBD=1923 XHG=1776 YBD=2731 YHG=2697>illness. " XBD=2065 XHG=1994 YBD=2732 YHG=2697>Dr. " XBD=2150 XHG=2105 YBD=2731 YHG=2697>F. " XBD=2235 XHG=2190 YBD=2731 YHG=2698>L. " XBD=2414 XHG=2275 YBD=2732 YHG=2697>GOLLA " XBD=2528 XHG=2444 YBD=2731 YHG=2697>drev " XBD=1637 XHG=1364 YBD=2791 YHG=2746>comparisons " XBD=1837 XHG=1657 YBD=2781 YHG=2746>between " XBD=1931 XHG=1861 YBD=2781 YHG=2746>the " XBD=2080 XHG=1956 YBD=2780 YHG=2746>tissue " XBD=2272 XHG=2104 YBD=2791 YHG=2746>damage " XBD=2338 XHG=2295 YBD=2780 YHG=2746>in " XBD=2529 XHG=2363 YBD=2781 YHG=2742>electrical " XBD=1601 XHG=1364 YBD=2829 YHG=2783>convulsion " XBD=1813 XHG=1639 YBD=2840 YHG=2796>therapy " XBD=1925 XHG=1845 YBD=2830 YHG=2796>and " XBD=2058 XHG=1964 YBD=2829 YHG=2796>that " XBD=2139 XHG=2097 YBD=2829 YHG=2796>in " XBD=2393 XHG=2176 YBD=2840 YHG=2794>prefrontal |>" XBD=2526 XHG=2424 YBD=2830 YHG=2795>leuco. " XBD=1492 XHG=1362 YBD=2888 YHG=2847>tomy, " XBD=1602 XHG=1520 YBD=2878 YHG=2844>and " XBD=1686 XHG=1636 YBD=2878 YHG=2845>he " XBD=1959 XHG=1719 YBD=2889 YHG=2844>deprecated " XBD=2065 XHG=1994 YBD=2878 YHG=2845>the " XBD=2222 XHG=2102 YBD=2878 YHG=2845>static " XBD=2479 XHG=2259 YBD=2889 YHG=2845>conception " XBD=2530 XHG=2499 YBD=2879 YHG=2840>of " XBD=1541 XHG=1364 YBD=2927 YHG=2892>cerebral " XBD=1752 XHG=1567 YBD=2927 YHG=2892>function " XBD=1869 XHG=1775 YBD=2927 YHG=2894>that " XBD=1978 XHG=1895 YBD=2926 YHG=2903>sees " XBD=2045 XHG=2002 YBD=2926 YHG=2893>in " XBD=2144 XHG=2062 YBD=2927 YHG=2893>this " XBD=2371 XHG=2164 YBD=2938 YHG=2893>operation " XBD=2527 XHG=2388 YBD=2936 YHG=2893>nothing " XBD=1439 XHG=1363 YBD=2975 YHG=2941>but " XBD=1520 XHG=1467 YBD=2975 YHG=2953>an " XBD=1825 XHG=1550 YBD=2975 YHG=2941>irremediable " XBD=2030 XHG=1856 YBD=2976 YHG=2945>trauma. " XBD=2225 XHG=2100 YBD=2976 YHG=2941>Other " XBD=2436 XHG=2257 YBD=2986 YHG=2953>surgeons " XBD=2525 XHG=2463 YBD=2976 YHG=2940>and " XBD=1480 XHG=1363 YBD=3024 YHG=2990>other " XBD=1786 XHG=1505 YBD=3035 YHG=2990>psychiatrists " XBD=2065 XHG=1806 YBD=3024 YHG=2989>contributed " XBD=2127 XHG=2082 YBD=3025 YHG=2992>to " XBD=2173 XHG=2147 YBD=3024 YHG=3002>a " XBD=2406 XHG=2191 YBD=3025 YHG=2990>discussion " XBD=2560 XHG=2422 YBD=3025 YHG=2991>which " XBD=1593 XHG=1363 YBD=3073 YHG=3039>sometimes " XBD=1897 XHG=1611 YBD=3083 YHG=3038>intentionally " XBD=1988 XHG=1908 YBD=3072 YHG=3038>and " XBD=2230 XHG=2001 YBD=3073 YHG=3039>sometimes " XBD=2297 XHG=2242 YBD=3083 YHG=3039>by " XBD=2525 XHG=2310 YBD=3084 YHG=3039>implication " XBD=1601 XHG=1362 YBD=3121 YHG=3087>underlined " XBD=1694 XHG=1624 YBD=3121 YHG=3088>the " XBD=1938 XHG=1718 YBD=3131 YHG=3098>vagueness " XBD=2007 XHG=1963 YBD=3121 YHG=3086>of " XBD=2098 XHG=2027 YBD=3121 YHG=3088>the " XBD=2360 XHG=2121 YBD=3122 YHG=3087>indications " XBD=2455 XHG=2383 YBD=3122 YHG=3089>and " XBD=2525 XHG=2474 YBD=3123 YHG=3088>the " XBD=1535 XHG=1362 YBD=3179 YHG=3135>dubiety " XBD=1606 XHG=1560 YBD=3169 YHG=3135>of " XBD=1697 XHG=1627 YBD=3169 YHG=3136>the " XBD=1917 XHG=1722 YBD=3169 YHG=3135>rationale " XBD=2027 XHG=1945 YBD=3169 YHG=3135>and " XBD=2209 XHG=2051 YBD=3170 YHG=3135>results. " XBD=2524 XHG=2263 YBD=3181 YHG=3135>Psychological " XBD=1466 XHG=1362 YBD=3217 YHG=3185>tests " XBD=1586 XHG=1489 YBD=3227 YHG=3195>may " XBD=1658 XHG=1608 YBD=3218 YHG=3183>be " XBD=1779 XHG=1680 YBD=3217 YHG=3184>used " XBD=1845 XHG=1801 YBD=3217 YHG=3186>to " XBD=2006 XHG=1869 YBD=3217 YHG=3184>decide " XBD=2065 XHG=2030 YBD=3217 YHG=3182>if " XBD=2197 XHG=2083 YBD=3217 YHG=3185>there " XBD=2253 XHG=2219 YBD=3217 YHG=3183>is " XBD=2523 XHG=2276 YBD=3219 YHG=3183>deterioration " XBD=1470 XHG=1363 YBD=3265 YHG=3231>after " XBD=1562 XHG=1492 YBD=3266 YHG=3232>the " XBD=1807 XHG=1586 YBD=3276 YHG=3232>operation. " XBD=1467 XHG=1416 YBD=3314 YHG=3280>In " XBD=1552 XHG=1480 YBD=3314 YHG=3291>our " XBD=1645 XHG=1565 YBD=3314 YHG=3279>last " XBD=1762 XHG=1657 YBD=3314 YHG=3279>issue " XBD=1845 XHG=1776 YBD=3314 YHG=3280>Dr. " XBD=2043 XHG=1861 YBD=3314 YHG=3280>HUTTON " XBD=2245 XHG=2056 YBD=3325 YHG=3280>reported " XBD=2309 XHG=2258 YBD=3314 YHG=3291>on " XBD=2368 XHG=2322 YBD=3315 YHG=3282>50 " XBD=2522 XHG=2380 YBD=3326 YHG=3281>patients " XBD=1525 XHG=1364 YBD=3363 YHG=3328>treated " XBD=1598 XHG=1541 YBD=3371 YHG=3328>by " XBD=1682 XHG=1612 YBD=3363 YHG=3329>the " XBD=1867 XHG=1699 YBD=3363 YHG=3329>method " XBD=1964 XHG=1883 YBD=3363 YHG=3329>and " XBD=2061 XHG=1979 YBD=3363 YHG=3340>was " XBD=2168 XHG=2078 YBD=3362 YHG=3328>able " XBD=2229 XHG=2184 YBD=3363 YHG=3331>to " XBD=2357 XHG=2246 YBD=3371 YHG=3329>point " XBD=2412 XHG=2372 YBD=3364 YHG=3332>to " XBD=2521 XHG=2426 YBD=3371 YHG=3339>many 1. Further Report on the 1938-1941 Shock Treated Cases in the Ontario Hospitals. Prepared by the Division of Statistics, Ontario Department of Health, January, 1943.

PHYSICAL APPROACH TO THE BRAIN

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" XBD=328 XHG=100 YBD=236 YHG=201>difficulties " XBD=398 XHG=355 YBD=236 YHG=202>in " XBD=496 XHG=424 YBD=237 YHG=202>the " XBD=803 XHG=523 YBD=237 YHG=204>maintenance " XBD=876 XHG=831 YBD=236 YHG=202>of " XBD=953 XHG=900 YBD=236 YHG=213>an " XBD=1180 XHG=980 YBD=246 YHG=202>adequate " XBD=1300 XHG=1209 YBD=237 YHG=211>con-" XBD=342 XHG=103 YBD=292 YHG=250>centration, " XBD=440 XHG=364 YBD=285 YHG=251>but " XBD=575 XHG=460 YBD=286 YHG=252>these " XBD=697 XHG=595 YBD=286 YHG=262>were " XBD=867 XHG=715 YBD=295 YHG=250>largely " XBD=1107 XHG=886 YBD=291 YHG=261>overcome, " XBD=1212 XHG=1130 YBD=285 YHG=251>and " XBD=1302 XHG=1231 YBD=284 YHG=250>the" XBD=351 XHG=102 YBD=343 YHG=298>application " XBD=419 XHG=374 YBD=334 YHG=299>of " XBD=642 XHG=438 YBD=345 YHG=299>penicillin " XBD=710 XHG=665 YBD=333 YHG=310>as " XBD=905 XHG=733 YBD=343 YHG=298>powder, " XBD=1107 XHG=931 YBD=332 YHG=298>solution " XBD=1174 XHG=1129 YBD=333 YHG=309>or " XBD=1300 XHG=1197 YBD=333 YHG=299>oint-" XBD=215 XHG=103 YBD=382 YHG=350>ment " XBD=396 XHG=242 YBD=393 YHG=348>proved " XBD=466 XHG=422 YBD=382 YHG=360>as " XBD=708 XHG=494 YBD=392 YHG=347>strikingly " XBD=949 XHG=734 YBD=380 YHG=346>successful " XBD=1019 XHG=975 YBD=380 YHG=357>as " XBD=1117 XHG=1046 YBD=381 YHG=346>did " XBD=1303 XHG=1143 YBD=391 YHG=346>general" XBD=432 XHG=103 YBD=431 YHG=395>administration " XBD=493 XHG=449 YBD=430 YHG=397>in " XBD=700 XHG=511 YBD=440 YHG=395>systemic " XBD=943 XHG=718 YBD=429 YHG=394>infections." XBD=262 XHG=154 YBD=479 YHG=444>Here " XBD=339 XHG=279 YBD=479 YHG=456>we " XBD=461 XHG=355 YBD=479 YHG=446>have " XBD=504 XHG=479 YBD=478 YHG=455>a " XBD=738 XHG=523 YBD=478 YHG=444>substance " XBD=889 XHG=756 YBD=477 YHG=443>whose " XBD=1159 XHG=905 YBD=488 YHG=443>therapeutic " XBD=1302 XHG=1177 YBD=488 YHG=444>possi-" XBD=251 XHG=104 YBD=527 YHG=491>bilities " XBD=370 XHG=264 YBD=527 YHG=493>have " XBD=480 XHG=383 YBD=536 YHG=492>only " XBD=626 XHG=492 YBD=536 YHG=491>begun " XBD=682 XHG=638 YBD=524 YHG=494>to " XBD=747 XHG=696 YBD=524 YHG=491>be " XBD=962 XHG=760 YBD=536 YHG=490>explored, " XBD=1132 XHG=977 YBD=537 YHG=491>though " XBD=1304 XHG=1147 YBD=527 YHG=491>clinical" XBD=217 XHG=104 YBD=576 YHG=541>trials " XBD=413 XHG=256 YBD=575 YHG=540>started " XBD=564 XHG=449 YBD=574 YHG=540>three " XBD=717 XHG=602 YBD=584 YHG=549>years " XBD=843 XHG=756 YBD=584 YHG=550>ago. " XBD=1185 XHG=898 YBD=575 YHG=540>Practitioners " XBD=1304 XHG=1223 YBD=575 YHG=540>will" XBD=267 XHG=105 YBD=629 YHG=590>wonder " XBD=391 XHG=287 YBD=630 YHG=600>now, " XBD=449 XHG=414 YBD=622 YHG=587>if " XBD=566 XHG=465 YBD=632 YHG=588>they |>" XBD=785 XHG=586 YBD=622 YHG=588>have not " XBD=1018 XHG=806 YBD=623 YHG=589>wondered " XBD=1187 XHG=1039 YBD=630 YHG=589>before, " XBD=1304 XHG=1210 YBD=634 YHG=590>why" XBD=280 XHG=104 YBD=683 YHG=638>supplies " XBD=371 XHG=303 YBD=671 YHG=648>are " XBD=468 XHG=394 YBD=671 YHG=639>not " XBD=570 XHG=491 YBD=680 YHG=639>yet " XBD=787 XHG=585 YBD=681 YHG=636>generally " XBD=1020 XHG=810 YBD=678 YHG=636>available, " XBD=1127 XHG=1045 YBD=672 YHG=638>and " XBD=1230 XHG=1149 YBD=671 YHG=637>will " XBD=1303 XHG=1253 YBD=671 YHG=638>be" XBD=389 XHG=104 YBD=731 YHG=685>disappointed " XBD=459 XHG=414 YBD=719 YHG=687>to " XBD=584 XHG=486 YBD=719 YHG=685>read " XBD=676 XHG=606 YBD=719 YHG=684>the " XBD=905 XHG=697 YBD=721 YHG=685>FLOREYS’ " XBD=1115 XHG=930 YBD=730 YHG=685>tailpiece " XBD=1303 XHG=1137 YBD=731 YHG=685>holding" XBD=177 XHG=105 YBD=768 YHG=737>out " XBD=247 XHG=193 YBD=768 YHG=745>no " XBD=471 XHG=263 YBD=779 YHG=736>prospects " XBD=534 XHG=488 YBD=768 YHG=733>of " XBD=616 XHG=545 YBD=768 YHG=734>the " XBD=819 XHG=633 YBD=779 YHG=734>shortage " XBD=953 XHG=835 YBD=779 YHG=734>being " XBD=1068 XHG=970 YBD=769 YHG=745>soon " XBD=1300 XHG=1083 YBD=769 YHG=734>remedied." XBD=188 XHG=104 YBD=817 YHG=782>The " XBD=298 XHG=207 YBD=817 YHG=783>best " XBD=375 XHG=315 YBD=817 YHG=793>we " XBD=471 XHG=395 YBD=817 YHG=794>can " XBD=595 XHG=489 YBD=829 YHG=783>hope " XBD=676 XHG=613 YBD=818 YHG=782>for " XBD=728 XHG=695 YBD=818 YHG=784>is " XBD=905 XHG=748 YBD=829 YHG=783>enough " XBD=987 XHG=924 YBD=818 YHG=783>for " XBD=1107 XHG=1005 YBD=818 YHG=782>local " XBD=1301 XHG=1126 YBD=829 YHG=782>applica-" XBD=192 XHG=105 YBD=868 YHG=832>tion " XBD=284 XHG=211 YBD=867 YHG=835>not " XBD=374 XHG=303 YBD=867 YHG=835>too " XBD=488 XHG=393 YBD=878 YHG=832>long " XBD=650 XHG=508 YBD=874 YHG=833>ahead, " XBD=733 XHG=670 YBD=868 YHG=832>for " XBD=777 XHG=753 YBD=867 YHG=845>a " XBD=972 XHG=796 YBD=868 YHG=833>mastoid " XBD=1138 XHG=990 YBD=867 YHG=833>wound " XBD=1234 XHG=1157 YBD=866 YHG=843>can " XBD=1303 XHG=1253 YBD=867 YHG=831>be" XBD=254 XHG=106 YBD=926 YHG=880>locally " XBD=436 XHG=276 YBD=916 YHG=882>treated " XBD=560 XHG=460 YBD=916 YHG=883>with " XBD=725 XHG=588 YBD=924 YHG=884>15,000 " XBD=905 XHG=751 YBD=917 YHG=882>Oxford " XBD=1050 XHG=928 YBD=923 YHG=882>units, " XBD=1253 XHG=1078 YBD=916 YHG=882>whereas " XBD=1304 XHG=1279 YBD=916 YHG=893>a" XBD=430 XHG=105 YBD=976 YHG=930>staphylococcal " XBD=708 XHG=464 YBD=977 YHG=931>septicaemia " XBD=838 XHG=742 YBD=975 YHG=942>may " XBD=973 XHG=871 YBD=966 YHG=931>need " XBD=1099 XHG=1006 YBD=964 YHG=931>that " XBD=1304 XHG=1133 YBD=965 YHG=934>amount" XBD=292 XHG=106 YBD=1025 YHG=978>3-hourly " XBD=367 XHG=304 YBD=1014 YHG=978>for " XBD=522 XHG=379 YBD=1015 YHG=980>weeks. " XBD=660 XHG=577 YBD=1014 YHG=980>The " XBD=872 XHG=673 YBD=1014 YHG=979>technical " XBD=1111 XHG=884 YBD=1014 YHG=979>difficulties " XBD=1301 XHG=1124 YBD=1024 YHG=978>of large-" XBD=210 XHG=106 YBD=1063 YHG=1028>scale " XBD=510 XHG=228 YBD=1063 YHG=1027>manufacture " XBD=634 XHG=528 YBD=1063 YHG=1029>have " XBD=722 XHG=653 YBD=1074 YHG=1032>yet " XBD=785 XHG=741 YBD=1063 YHG=1032>to " XBD=854 XHG=804 YBD=1063 YHG=1028>be " XBD=1082 XHG=874 YBD=1063 YHG=1040>overcome " XBD=1183 XHG=1101 YBD=1063 YHG=1028>and " XBD=1305 XHG=1201 YBD=1063 YHG=1039>even" XBD=149 XHG=107 YBD=1112 YHG=1078>in " XBD=232 XHG=162 YBD=1112 YHG=1078>the " XBD=481 XHG=246 YBD=1122 YHG=1076>laboratory " XBD=616 XHG=495 YBD=1112 YHG=1078>much " XBD=772 XHG=632 YBD=1113 YHG=1077>skilled " XBD=896 XHG=786 YBD=1112 YHG=1078>work " XBD=1045 XHG=910 YBD=1124 YHG=1078>brings " XBD=1135 XHG=1059 YBD=1113 YHG=1078>but " XBD=1173 XHG=1149 YBD=1112 YHG=1090>a " XBD=1306 XHG=1188 YBD=1112 YHG=1077>small" XBD=255 XHG=104 YBD=1160 YHG=1129>return. " XBD=394 XHG=308 YBD=1161 YHG=1126>The " XBD=508 XHG=407 YBD=1172 YHG=1127>drug " XBD=555 XHG=521 YBD=1160 YHG=1127>is " XBD=707 XHG=567 YBD=1172 YHG=1127>highly " XBD=925 XHG=719 YBD=1162 YHG=1126>labile-it " XBD=971 XHG=937 YBD=1161 YHG=1127>is " XBD=1138 XHG=983 YBD=1172 YHG=1127>readily " XBD=1305 XHG=1151 YBD=1162 YHG=1127>broken" XBD=222 XHG=104 YBD=1210 YHG=1175>down " XBD=297 XHG=240 YBD=1220 YHG=1175>by " XBD=425 XHG=314 YBD=1210 YHG=1175>acids " XBD=527 XHG=444 YBD=1210 YHG=1176>and " XBD=701 XHG=545 YBD=1218 YHG=1176>alkalis, " XBD=778 XHG=721 YBD=1221 YHG=1176>by " XBD=903 XHG=795 YBD=1218 YHG=1176>heat, " XBD=980 XHG=924 YBD=1222 YHG=1176>by " XBD=1152 XHG=1000 YBD=1211 YHG=1177>certain " XBD=1305 XHG=1170 YBD=1221 YHG=1176>heavy" XBD=259 XHG=103 YBD=1266 YHG=1224>metals, " XBD=367 XHG=285 YBD=1259 YHG=1225>and " XBD=517 XHG=394 YBD=1268 YHG=1225>(most " XBD=691 XHG=541 YBD=1260 YHG=1226>serious " XBD=762 XHG=717 YBD=1260 YHG=1225>of |>" XBD=852 XHG=783 YBD=1274 YHG=1225>all) " XBD=937 XHG=881 YBD=1271 YHG=1226>by " XBD=1086 XHG=961 YBD=1271 YHG=1237>many " XBD=1304 XHG=1110 YBD=1260 YHG=1225>bacterial" XBD=289 XHG=102 YBD=1319 YHG=1284>enzymes " XBD=433 XHG=303 YBD=1309 YHG=1273>which " XBD=586 XHG=447 YBD=1309 YHG=1285>means " XBD=694 XHG=601 YBD=1310 YHG=1275>that " XBD=949 XHG=708 YBD=1321 YHG=1275>production " XBD=1072 XHG=962 YBD=1309 YHG=1277>must " XBD=1137 XHG=1087 YBD=1309 YHG=1274>be " XBD=1307 XHG=1152 YBD=1309 YHG=1275>carried" XBD=176 XHG=103 YBD=1358 YHG=1326>out " XBD=297 XHG=198 YBD=1358 YHG=1323>with " XBD=436 XHG=320 YBD=1358 YHG=1324>strict " XBD=623 XHG=459 YBD=1369 YHG=1325>asepsis. " XBD=815 XHG=676 YBD=1359 YHG=1324>Funds " XBD=899 XHG=837 YBD=1359 YHG=1323>for " XBD=1104 XHG=921 YBD=1359 YHG=1324>research " XBD=1194 XHG=1126 YBD=1359 YHG=1336>are " XBD=1306 XHG=1218 YBD=1358 YHG=1324>said" XBD=147 XHG=103 YBD=1407 YHG=1375>to " XBD=221 XHG=171 YBD=1407 YHG=1372>be " XBD=390 XHG=245 YBD=1418 YHG=1372>ample, " XBD=499 XHG=416 YBD=1408 YHG=1373>and " XBD=712 XHG=522 YBD=1419 YHG=1374>Imperial " XBD=937 XHG=736 YBD=1408 YHG=1373>Chemical " XBD=1185 XHG=960 YBD=1408 YHG=1373>Industries " XBD=1303 XHG=1208 YBD=1408 YHG=1373>Ltd." XBD=148 XHG=104 YBD=1456 YHG=1432>as " XBD=256 XHG=167 YBD=1456 YHG=1420>well " XBD=318 XHG=273 YBD=1456 YHG=1433>as " XBD=408 XHG=337 YBD=1456 YHG=1422>the " XBD=516 XHG=427 YBD=1457 YHG=1433>new " XBD=800 XHG=534 YBD=1468 YHG=1423>Therapeutic " XBD=1021 XHG=820 YBD=1457 YHG=1423>Research " XBD=1306 XHG=1040 YBD=1468 YHG=1422>Corporation" XBD=172 XHG=104 YBD=1505 YHG=1481>are " XBD=396 XHG=214 YBD=1516 YHG=1470>tackling " XBD=511 XHG=440 YBD=1505 YHG=1472>the " XBD=822 XHG=556 YBD=1517 YHG=1471>outstanding " XBD=1080 XHG=866 YBD=1517 YHG=1472>problems. " XBD=1191 XHG=1134 YBD=1506 YHG=1471>At " XBD=1305 XHG=1235 YBD=1506 YHG=1472>the" XBD=267 XHG=103 YBD=1565 YHG=1522>request " XBD=330 XHG=284 YBD=1555 YHG=1519>of " XBD=416 XHG=344 YBD=1555 YHG=1521>the " XBD=625 XHG=434 YBD=1565 YHG=1520>Ministry " XBD=689 XHG=643 YBD=1555 YHG=1520>of " XBD=872 XHG=704 YBD=1566 YHG=1520>Supply, " XBD=917 XHG=892 YBD=1554 YHG=1532>a " XBD=1178 XHG=935 YBD=1566 YHG=1520>production " XBD=1314 XHG=1198 YBD=1555 YHG=1532>com--" XBD=245 XHG=103 YBD=1604 YHG=1569>mittee " XBD=302 XHG=257 YBD=1604 YHG=1571>to " XBD=517 XHG=315 YBD=1615 YHG=1569>integrate " XBD=644 XHG=530 YBD=1604 YHG=1570>these " XBD=797 XHG=658 YBD=1604 YHG=1569>efforts " XBD=884 XHG=811 YBD=1604 YHG=1570>has " XBD=1000 XHG=898 YBD=1604 YHG=1569>been " XBD=1075 XHG=1014 YBD=1604 YHG=1572>set " XBD=1158 XHG=1089 YBD=1615 YHG=1581>up, " XBD=1304 XHG=1172 YBD=1615 YHG=1581>repre-" XBD=263 XHG=104 YBD=1665 YHG=1618>senting " XBD=357 XHG=285 YBD=1653 YHG=1618>the " XBD=534 XHG=380 YBD=1654 YHG=1618>British " XBD=668 XHG=558 YBD=1653 YHG=1618>firms " XBD=912 XHG=691 YBD=1653 YHG=1619>interested " XBD=1017 XHG=935 YBD=1653 YHG=1620>and " XBD=1111 XHG=1039 YBD=1653 YHG=1619>the " XBD=1305 XHG=1133 YBD=1654 YHG=1619>Medical" XBD=307 XHG=105 YBD=1703 YHG=1668>Research " XBD=507 XHG=329 YBD=1703 YHG=1667>Council. " XBD=769 XHG=556 YBD=1702 YHG=1668>American " XBD=899 XHG=789 YBD=1702 YHG=1667>firms " XBD=1099 XHG=920 YBD=1713 YHG=1668>working " XBD=1174 XHG=1121 YBD=1703 YHG=1680>on " XBD=1303 XHG=1194 YBD=1713 YHG=1669>peni-" XBD=213 XHG=107 YBD=1751 YHG=1717>cillin " XBD=340 XHG=233 YBD=1752 YHG=1717>have " XBD=460 XHG=360 YBD=1763 YHG=1717>kept " XBD=552 XHG=482 YBD=1752 YHG=1717>the " XBD=686 XHG=574 YBD=1752 YHG=1716>MRC " XBD=906 XHG=707 YBD=1751 YHG=1716>informed " XBD=972 XHG=927 YBD=1751 YHG=1716>of " XBD=1094 XHG=989 YBD=1752 YHG=1718>their " XBD=1302 XHG=1115 YBD=1762 YHG=1717>findings." XBD=155 XHG=105 YBD=1801 YHG=1767>In " XBD=243 XHG=172 YBD=1801 YHG=1767>the " XBD=397 XHG=263 YBD=1802 YHG=1766>States " XBD=470 XHG=416 YBD=1801 YHG=1766>all " XBD=559 XHG=489 YBD=1801 YHG=1767>the " XBD=782 XHG=578 YBD=1812 YHG=1766>penicillin " XBD=917 XHG=799 YBD=1801 YHG=1766>made " XBD=969 XHG=936 YBD=1801 YHG=1767>is " XBD=1131 XHG=987 YBD=1811 YHG=1766>pooled " XBD=1232 XHG=1150 YBD=1801 YHG=1767>and " XBD=1304 XHG=1250 YBD=1801 YHG=1767>its" XBD=173 XHG=103 YBD=1851 YHG=1828>use " XBD=223 XHG=189 YBD=1850 YHG=1816>is " XBD=463 XHG=242 YBD=1851 YHG=1816>controlled " XBD=537 XHG=480 YBD=1861 YHG=1816>by " XBD=577 XHG=553 YBD=1851 YHG=1828>a " XBD=852 XHG=596 YBD=1858 YHG=1816>committee ; " XBD=957 XHG=886 YBD=1850 YHG=1816>the " XBD=1085 XHG=973 YBD=1851 YHG=1816>MRC " XBD=1135 XHG=1102 YBD=1850 YHG=1816>is " XBD=1304 XHG=1154 YBD=1862 YHG=1817>setting" XBD=159 XHG=103 YBD=1912 YHG=1878>up " XBD=205 XHG=181 YBD=1900 YHG=1878>a " XBD=378 XHG=228 YBD=1900 YHG=1865>similar " XBD=641 XHG=402 YBD=1910 YHG=1865>controlling " XBD=895 XHG=665 YBD=1900 YHG=1865>committee " XBD=1023 XHG=918 YBD=1900 YHG=1865>here.|>" XBD=138 XHG=132 YBD=1933 YHG=1928>’ " XBD=283 XHG=154 YBD=1951 YHG=1915>While " XBD=388 XHG=305 YBD=1950 YHG=1915>this " XBD=598 XHG=412 YBD=1960 YHG=1916>shortage " XBD=737 XHG=621 YBD=1949 YHG=1914>holds " XBD=1018 XHG=759 YBD=1960 YHG=1926>upprogress " XBD=1099 XHG=1040 YBD=1948 YHG=1926>we " XBD=1198 XHG=1123 YBD=1949 YHG=1926>can " XBD=1304 XHG=1221 YBD=1950 YHG=1915>still" XBD=207 XHG=102 YBD=2011 YHG=1965>hope " XBD=290 XHG=228 YBD=2000 YHG=1964>for " XBD=338 XHG=313 YBD=1999 YHG=1977>a " XBD=562 XHG=361 YBD=2000 YHG=1965>short-cut " XBD=629 XHG=586 YBD=1999 YHG=1976>or " XBD=677 XHG=652 YBD=1999 YHG=1975>a " XBD=904 XHG=701 YBD=1998 YHG=1963>collateral " XBD=1174 XHG=927 YBD=1999 YHG=1964>circulation. " XBD=1303 XHG=1229 YBD=2000 YHG=1964>We" XBD=155 XHG=103 YBD=2049 YHG=2026>no " XBD=309 XHG=172 YBD=2060 YHG=2014>longer " XBD=432 XHG=326 YBD=2049 YHG=2015>have " XBD=494 XHG=448 YBD=2049 YHG=2017>to " XBD=671 XHG=512 YBD=2059 YHG=2014>depend " XBD=742 XHG=688 YBD=2048 YHG=2025>on " XBD=1022 XHG=758 YBD=2048 YHG=2013>willow-trees " XBD=1101 XHG=1038 YBD=2048 YHG=2012>for " XBD=1191 XHG=1118 YBD=2048 YHG=2026>our " XBD=1301 XHG=1209 YBD=2059 YHG=2026>sup-" XBD=201 XHG=102 YBD=2110 YHG=2063>plies " XBD=264 XHG=219 YBD=2099 YHG=2063>of " XBD=519 XHG=279 YBD=2109 YHG=2063>salicylates, " XBD=584 XHG=540 YBD=2098 YHG=2075>so " XBD=696 XHG=602 YBD=2108 YHG=2063>why " XBD=823 XHG=713 YBD=2098 YHG=2066>must " XBD=899 XHG=841 YBD=2097 YHG=2074>we " XBD=1003 XHG=916 YBD=2108 YHG=2062>rely " XBD=1073 XHG=1020 YBD=2098 YHG=2075>on " XBD=1161 XHG=1091 YBD=2097 YHG=2064>the " XBD=1301 XHG=1179 YBD=2098 YHG=2063>much" XBD=212 XHG=103 YBD=2149 YHG=2125>more " XBD=459 XHG=237 YBD=2159 YHG=2113>capricious " XBD=736 XHG=483 YBD=2147 YHG=2113>Penicillium |>" XBD=932 XHG=760 YBD=2148 YHG=2117>notatitm " XBD=1018 XHG=955 YBD=2147 YHG=2112>for " XBD=1115 XHG=1042 YBD=2147 YHG=2124>our " XBD=1299 XHG=1139 YBD=2158 YHG=2112>penicil-

lin . " XBD=571 XHG=250 YBD=2207 YHG=2162>Unfortunately " XBD=677 XHG=607 YBD=2196 YHG=2162>the " XBD=915 XHG=716 YBD=2207 YHG=2162>synthesis " XBD=998 XHG=953 YBD=2197 YHG=2161>of " XBD=1182 XHG=1031 YBD=2208 YHG=2162>aspirin " XBD=1301 XHG=1219 YBD=2198 YHG=2174>was" XBD=245 XHG=104 YBD=2259 YHG=2212>simple " XBD=478 XHG=263 YBD=2258 YHG=2212>compared " XBD=594 XHG=494 YBD=2246 YHG=2212>with " XBD=704 XHG=610 YBD=2246 YHG=2212>that " XBD=766 XHG=721 YBD=2246 YHG=2211>of " XBD=991 XHG=777 YBD=2257 YHG=2211>penicillin, " XBD=1080 XHG=1010 YBD=2246 YHG=2213>the " XBD=1300 XHG=1099 YBD=2246 YHG=2215>structure" XBD=149 XHG=104 YBD=2296 YHG=2260>of " XBD=305 XHG=176 YBD=2296 YHG=2261>which " XBD=371 XHG=337 YBD=2295 YHG=2262>is " XBD=501 XHG=404 YBD=2306 YHG=2260>only " XBD=622 XHG=531 YBD=2295 YHG=2272>now " XBD=869 XHG=652 YBD=2306 YHG=2261>beginning " XBD=944 XHG=899 YBD=2294 YHG=2264>to " XBD=1026 XHG=976 YBD=2295 YHG=2261>be " XBD=1297 XHG=1057 YBD=2295 YHG=2260>elucidated." XBD=259 XHG=103 YBD=2355 YHG=2309>Lately, " XBD=436 XHG=282 YBD=2345 YHG=2310>Oxford workers " XBD=781 XHG=644 YBD=2344 YHG=2310>1 have " XBD=993 XHG=801 YBD=2345 YHG=2310>obtained " XBD=1036 XHG=1013 YBD=2344 YHG=2322>a " XBD=1301 XHG=1057 YBD=2345 YHG=2310>substantial" XBD=196 XHG=102 YBD=2405 YHG=2363>part " XBD=273 XHG=227 YBD=2394 YHG=2359>of " XBD=370 XHG=299 YBD=2394 YHG=2360>the " XBD=605 XHG=402 YBD=2405 YHG=2359>penicillin " XBD=829 XHG=636 YBD=2394 YHG=2359>molecule " XBD=898 XHG=855 YBD=2393 YHG=2360>in " XBD=1154 XHG=925 YBD=2405 YHG=2359>crystalline " XBD=1298 XHG=1181 YBD=2395 YHG=2358>form." XBD=198 XHG=102 YBD=2443 YHG=2409>This " XBD=672 XHG=236 YBD=2454 YHG=2409>nitrogen-containing " XBD=953 XHG=712 YBD=2454 YHG=2409>compound, " XBD=1298 XHG=992 YBD=2454 YHG=2408>penicillamine," XBD=307 XHG=104 YBD=2503 YHG=2458>produced " XBD=380 XHG=324 YBD=2502 YHG=2458>by " XBD=624 XHG=396 YBD=2503 YHG=2457>hydrolysis " XBD=686 XHG=642 YBD=2492 YHG=2457>of " XBD=912 XHG=699 YBD=2503 YHG=2457>penicillin, " XBD=1101 XHG=931 YBD=2503 YHG=2468>appears " XBD=1161 XHG=1117 YBD=2492 YHG=2460>to " XBD=1229 XHG=1179 YBD=2492 YHG=2458>be " XBD=1300 XHG=1246 YBD=2492 YHG=2469>an" XBD=359 XHG=101 YBD=2548 YHG=2507>amino-acid, " XBD=463 XHG=388 YBD=2541 YHG=2507>but " XBD=588 XHG=489 YBD=2541 YHG=2507>with " XBD=834 XHG=613 YBD=2553 YHG=2508>properties " XBD=958 XHG=860 YBD=2553 YHG=2519>very " XBD=1169 XHG=983 YBD=2542 YHG=2506>different " XBD=1299 XHG=1195 YBD=2541 YHG=2506>from" XBD=173 XHG=103 YBD=2589 YHG=2555>the " XBD=346 XHG=198 YBD=2590 YHG=2556>known " XBD=648 XHG=372 YBD=2597 YHG=2556>amino-acids, " XBD=905 XHG=676 YBD=2602 YHG=2557>suggesting " XBD=955 XHG=931 YBD=2591 YHG=2569>a " XBD=1150 XHG=980 YBD=2591 YHG=2555>relation " XBD=1221 XHG=1175 YBD=2591 YHG=2559>to " XBD=1300 XHG=1247 YBD=2590 YHG=2568>an" XBD=375 XHG=101 YBD=2649 YHG=2604>amino-sugar " XBD=482 XHG=400 YBD=2639 YHG=2605>and " XBD=683 XHG=506 YBD=2639 YHG=2605>ascorbic " XBD=810 XHG=708 YBD=2639 YHG=2606>acid. " XBD=1045 XHG=864 YBD=2640 YHG=2605>Another " XBD=1300 XHG=1070 YBD=2650 YHG=2605>crystalline" XBD=488 XHG=104 YBD=2698 YHG=2653>product-penillic " XBD=727 XHG=512 YBD=2688 YHG=2654>acid-has " XBD=852 XHG=746 YBD=2688 YHG=2654>since " XBD=975 XHG=873 YBD=2688 YHG=2654>been produced " XBD=1301 XHG=1211 YBD=2698 YHG=2654>2 by" XBD=195 XHG=101 YBD=2736 YHG=2701>acid " XBD=483 XHG=215 YBD=2736 YHG=2702>inactivation " XBD=551 XHG=506 YBD=2736 YHG=2702>of " XBD=782 XHG=569 YBD=2747 YHG=2702>penicillin, " XBD=884 XHG=803 YBD=2737 YHG=2703>and " XBD=984 XHG=902 YBD=2737 YHG=2703>this " XBD=1082 XHG=1003 YBD=2736 YHG=2702>will " XBD=1301 XHG=1102 YBD=2748 YHG=2702>probably" XBD=227 XHG=103 YBD=2795 YHG=2761>prove " XBD=294 XHG=250 YBD=2784 YHG=2753>to " XBD=369 XHG=319 YBD=2784 YHG=2750>be " XBD=418 XHG=393 YBD=2785 YHG=2762>a " XBD=569 XHG=440 YBD=2796 YHG=2750>larger " XBD=685 XHG=592 YBD=2796 YHG=2754>part " XBD=754 XHG=710 YBD=2786 YHG=2751>of " XBD=844 XHG=774 YBD=2786 YHG=2752>the " XBD=1069 XHG=867 YBD=2797 YHG=2751>penicillin " XBD=1298 XHG=1093 YBD=2787 YHG=2751>molecule." XBD=229 XHG=99 YBD=2834 YHG=2800>These " XBD=328 XHG=261 YBD=2834 YHG=2810>are " XBD=547 XHG=359 YBD=2834 YHG=2798>valuable " XBD=688 XHG=579 YBD=2845 YHG=2803>steps " XBD=894 XHG=718 YBD=2836 YHG=2801>towards " XBD=994 XHG=924 YBD=2835 YHG=2801>the " XBD=1226 XHG=1025 YBD=2835 YHG=2801>short-cut " XBD=1303 XHG=1258 YBD=2834 YHG=2800>of" XBD=316 XHG=101 YBD=2893 YHG=2848>synthesis, " XBD=417 XHG=341 YBD=2882 YHG=2848>but " XBD=551 XHG=440 YBD=2893 YHG=2847>early " XBD=680 XHG=574 YBD=2884 YHG=2860>ones. " XBD=818 XHG=735 YBD=2883 YHG=2850>The " XBD=956 XHG=842 YBD=2884 YHG=2850>other " XBD=1128 XHG=980 YBD=2883 YHG=2850>chance " XBD=1184 XHG=1150 YBD=2883 YHG=2851>is " XBD=1300 XHG=1207 YBD=2884 YHG=2850>that" XBD=273 XHG=100 YBD=2931 YHG=2897>another " XBD=517 XHG=286 YBD=2942 YHG=2897>compound " XBD=608 XHG=529 YBD=2931 YHG=2897>will " XBD=670 XHG=620 YBD=2931 YHG=2898>be " XBD=810 XHG=682 YBD=2932 YHG=2898>found " XBD=950 XHG=821 YBD=2932 YHG=2899>which " XBD=1041 XHG=963 YBD=2932 YHG=2898>will " XBD=1101 XHG=1051 YBD=2932 YHG=2898>be " XBD=1154 XHG=1111 YBD=2932 YHG=2910>as " XBD=1298 XHG=1164 YBD=2942 YHG=2900>upset-" XBD=189 XHG=102 YBD=2991 YHG=2946>ting " XBD=254 XHG=208 YBD=2991 YHG=2948>to " XBD=469 XHG=274 YBD=2979 YHG=2945>bacterial " XBD=745 XHG=489 YBD=2981 YHG=2937>metabolism " XBD=809 XHG=765 YBD=2980 YHG=2958>as " XBD=1033 XHG=829 YBD=2992 YHG=2946>penicillin " XBD=1129 XHG=1054 YBD=2981 YHG=2947>but " XBD=1230 XHG=1149 YBD=2980 YHG=2946>will " XBD=1300 XHG=1250 YBD=2980 YHG=2946>be" XBD=229 XHG=100 YBD=3040 YHG=2994>.easily " XBD=380 XHG=249 YBD=3030 YHG=2994>made. " XBD=517 XHG=435 YBD=3028 YHG=2994>Yet " XBD=621 XHG=539 YBD=3031 YHG=2994>this " XBD=772 XHG=642 YBD=3040 YHG=2996>might " XBD=912 XHG=794 YBD=3030 YHG=3006>mean " XBD=1003 XHG=933 YBD=3029 YHG=2995>the " XBD=1104 XHG=1024 YBD=3030 YHG=2994>loss " XBD=1172 XHG=1127 YBD=3029 YHG=2994>of " XBD=1300 XHG=1189 YBD=3030 YHG=2996>what" XBD=233 XHG=104 YBD=3090 YHG=3044>might " XBD=302 XHG=253 YBD=3078 YHG=3044>be " XBD=347 XHG=322 YBD=3078 YHG=3055>a " XBD=547 XHG=365 YBD=3088 YHG=3043>triumph " XBD=628 XHG=565 YBD=3078 YHG=3042>for " XBD=798 XHG=647 YBD=3078 YHG=3044>British " XBD=1146 XHG=817 YBD=3090 YHG=3044>bacteriologists, " XBD=1298 XHG=1168 YBD=3078 YHG=3044>chem-" XBD=190 XHG=99 YBD=3134 YHG=3093>ists, " XBD=314 XHG=213 YBD=3138 YHG=3093>drug " XBD=656 XHG=335 YBD=3127 YHG=3092>manufacturers " XBD=760 XHG=678 YBD=3127 YHG=3092>and " XBD=996 XHG=781 YBD=3127 YHG=3092>clinicians. " XBD=1298 XHG=1050 YBD=3134 YHG=3092>Meanwhile," XBD=288 XHG=104 YBD=3176 YHG=3142>however " XBD=429 XHG=306 YBD=3175 YHG=3141>much " XBD=507 XHG=447 YBD=3175 YHG=3152>we " XBD=659 XHG=526 YBD=3175 YHG=3141>would " XBD=758 XHG=677 YBD=3175 YHG=3141>like " XBD=801 XHG=777 YBD=3174 YHG=3152>a " XBD=895 XHG=819 YBD=3187 YHG=3140>few " XBD=1111 XHG=913 YBD=3186 YHG=3152>grammes " XBD=1175 XHG=1130 YBD=3176 YHG=3141>of " XBD=1299 XHG=1189 YBD=3186 YHG=3141>peni-|>" XBD=212 XHG=101 YBD=3233 YHG=3190>cillin " XBD=286 XHG=223 YBD=3224 YHG=3189>for " XBD=352 XHG=298 YBD=3224 YHG=3201>an " XBD=591 XHG=364 YBD=3224 YHG=3188>individual " XBD=772 XHG=602 YBD=3234 YHG=3189>patient, " XBD=819 XHG=786 YBD=3222 YHG=3189>it " XBD=865 XHG=831 YBD=3223 YHG=3183>is " XBD=984 XHG=877 YBD=3234 YHG=3190>right " XBD=1089 XHG=996 YBD=3224 YHG=3191>that " XBD=1172 XHG=1102 YBD=3224 YHG=3190>the " XBD=1302 XHG=1185 YBD=3224 YHG=3188>small" XBD=274 XHG=100 YBD=3273 YHG=3242>amount " XBD=415 XHG=294 YBD=3273 YHG=3239>made " XBD=581 XHG=436 YBD=3273 YHG=3238>should " XBD=652 XHG=602 YBD=3282 YHG=3249>go " XBD=719 XHG=673 YBD=3271 YHG=3240>to " XBD=810 XHG=740 YBD=3272 YHG=3238>the " XBD=1022 XHG=834 YBD=3272 YHG=3238>chemists " XBD=1104 XHG=1042 YBD=3272 YHG=3237>for " XBD=1301 XHG=1126 YBD=3282 YHG=3238>analysis" XBD=149 XHG=99 YBD=3322 YHG=3299>or " XBD=224 XHG=174 YBD=3322 YHG=3287>be " XBD=395 XHG=250 YBD=3332 YHG=3287>pooled " XBD=503 XHG=421 YBD=3321 YHG=3287>and " XBD=628 XHG=528 YBD=3321 YHG=3286>used " XBD=696 XHG=652 YBD=3320 YHG=3286>in " XBD=914 XHG=722 YBD=3331 YHG=3284>carefully " XBD=1114 XHG=939 YBD=3331 YHG=3285>planned " XBD=1296 XHG=1141 YBD=3321 YHG=3286>clinical" XBD=215 XHG=98 YBD=3370 YHG=3335>trials " XBD=358 XHG=231 YBD=3370 YHG=3336>under " XBD=443 XHG=373 YBD=3370 YHG=3336>the " XBD=533 XHG=460 YBD=3380 YHG=3347>eye " XBD=594 XHG=549 YBD=3371 YHG=3335>of " XBD=631 XHG=606 YBD=3370 YHG=3347>a " XBD=759 XHG=646 YBD=3370 YHG=3334>MRC " XBD=1016 XHG=776 YBD=3369 YHG=3335>committee.

1. Abraham, E. P., Chain, E., Baker, W. and Robinson, R. Nature,Lond. Jan. 23, 1943; p. 107.

2. Duffin, W. M. and Smith, S. Ibid, Feb. 27, 1943, p. 251.

PHYSICAL APPROACH TO THE BRAIN " XBD=1469 XHG=1416 YBD=326 YHG=291>IN " XBD=1575 XHG=1504 YBD=326 YHG=291>the " XBD=1702 XHG=1608 YBD=326 YHG=290>field " XBD=1782 XHG=1740 YBD=326 YHG=291>of " XBD=1969 XHG=1817 YBD=325 YHG=290>mental " XBD=2182 XHG=2002 YBD=325 YHG=290>disorder " XBD=2356 XHG=2216 YBD=324 YHG=289>failure " XBD=2425 XHG=2384 YBD=324 YHG=293>to " XBD=2527 XHG=2455 YBD=335 YHG=290>plan" XBD=1619 XHG=1365 YBD=385 YHG=340>therapeutic " XBD=1905 XHG=1637 YBD=385 YHG=330>experiments " XBD=2000 XHG=1926 YBD=374 YHG=339>has " XBD=2090 XHG=2024 YBD=373 YHG=338>led " XBD=2163 XHG=2118 YBD=373 YHG=342>to " XBD=2312 XHG=2192 YBD=374 YHG=338>much " XBD=2526 XHG=2341 YBD=374 YHG=337>confusion." XBD=1534 XHG=1365 YBD=429 YHG=388>Insulin, " XBD=1753 XHG=1567 YBD=434 YHG=385>leptazol, " XBD=1985 XHG=1788 YBD=422 YHG=387>electrical " XBD=2285 XHG=2020 YBD=428 YHG=388>convulsions, " XBD=2398 XHG=2319 YBD=421 YHG=387>and " XBD=2526 XHG=2425 YBD=421 YHG=386>leuco." XBD=1483 XHG=1364 YBD=482 YHG=440>tomy " XBD=1602 XHG=1498 YBD=471 YHG=437>have " XBD=1730 XHG=1619 YBD=471 YHG=448>come " XBD=1799 XHG=1746 YBD=471 YHG=448>on " XBD=1884 XHG=1814 YBD=471 YHG=436>the " XBD=2012 XHG=1900 YBD=481 YHG=440>stage " XBD=2070 XHG=2028 YBD=470 YHG=437>in " XBD=2194 XHG=2085 YBD=477 YHG=440>turn, " XBD=2287 XHG=2213 YBD=470 YHG=436>but " XBD=2410 XHG=2302 YBD=469 YHG=436>there " XBD=2454 XHG=2424 YBD=468 YHG=435>is " XBD=2528 XHG=2467 YBD=470 YHG=435>still" XBD=1628 XHG=1366 YBD=530 YHG=488>controversy " XBD=1779 XHG=1652 YBD=520 YHG=486>about " XBD=1907 XHG=1803 YBD=519 YHG=486>their " XBD=2096 XHG=1932 YBD=529 YHG=485>efficacy " XBD=2202 XHG=2120 YBD=519 YHG=485>and " XBD=2295 XHG=2226 YBD=518 YHG=484>the " XBD=2527 XHG=2319 YBD=518 YHG=483>indications" XBD=1427 XHG=1364 YBD=569 YHG=533>for " XBD=1559 XHG=1454 YBD=569 YHG=534>their " XBD=1668 XHG=1587 YBD=569 YHG=546>use. " XBD=1821 XHG=1740 YBD=569 YHG=534>Yet " XBD=1907 XHG=1856 YBD=568 YHG=534>R. " XBD=1987 XHG=1940 YBD=568 YHG=533>A. |>" XBD=2209 XHG=2011 YBD=568 YHG=533>FisHER’s " XBD=2347 XHG=2242 YBD=567 YHG=533>book " XBD=2408 XHG=2376 YBD=566 YHG=532>is " XBD=2528 XHG=2435 YBD=578 YHG=531>fairly" XBD=1512 XHG=1365 YBD=628 YHG=583>widely " XBD=1635 XHG=1538 YBD=617 YHG=583>read " XBD=1809 XHG=1663 YBD=628 YHG=595>among " XBD=1997 XHG=1837 YBD=618 YHG=583>doctors " XBD=2108 XHG=2026 YBD=617 YHG=583>and " XBD=2357 XHG=2139 YBD=627 YHG=580>biologists, " XBD=2455 XHG=2382 YBD=615 YHG=580>and " XBD=2526 XHG=2479 YBD=616 YHG=570>ex." XBD=1547 XHG=1365 YBD=676 YHG=631>perience " XBD=1617 XHG=1572 YBD=666 YHG=634>at " XBD=1914 XHG=1643 YBD=666 YHG=632>Rothamsted " XBD=2082 XHG=1939 YBD=666 YHG=631>should " XBD=2219 XHG=2107 YBD=665 YHG=642>serve " XBD=2287 XHG=2244 YBD=664 YHG=642>as " XBD=2339 XHG=2315 YBD=664 YHG=642>a " XBD=2528 XHG=2361 YBD=665 YHG=629>reminder" XBD=1460 XHG=1365 YBD=714 YHG=680>that " XBD=1709 XHG=1499 YBD=724 YHG=679>biological " XBD=2021 XHG=1753 YBD=725 YHG=680>experiments " XBD=2166 XHG=2064 YBD=714 YHG=680>need " XBD=2253 XHG=2209 YBD=713 YHG=682>to " XBD=2338 XHG=2289 YBD=713 YHG=679>be " XBD=2526 XHG=2369 YBD=723 YHG=678>planned." XBD=1531 XHG=1366 YBD=762 YHG=728>LIONEL " XBD=1787 XHG=1557 YBD=770 YHG=729>PENROSE,1 " XBD=2028 XHG=1814 YBD=773 YHG=728>surveying " XBD=2151 XHG=2054 YBD=762 YHG=728>with " XBD=2204 XHG=2180 YBD=762 YHG=740>a " XBD=2399 XHG=2231 YBD=762 YHG=726>suitable " XBD=2527 XHG=2420 YBD=762 YHG=728>statis." XBD=1463 XHG=1365 YBD=811 YHG=776>tical " XBD=1714 XHG=1499 YBD=823 YHG=777>technique " XBD=1820 XHG=1750 YBD=812 YHG=778>the " XBD=1957 XHG=1860 YBD=812 YHG=778>1600 " XBD=2172 XHG=1993 YBD=822 YHG=777>patients " XBD=2297 XHG=2209 YBD=811 YHG=776>who " XBD=2417 XHG=2340 YBD=811 YHG=776>had " XBD=2528 XHG=2451 YBD=812 YHG=776>been" XBD=1682 XHG=1366 YBD=872 YHG=826>given &dquo;shock " XBD=1970 XHG=1709 YBD=861 YHG=825>treatment &dquo; " XBD=2051 XHG=2007 YBD=860 YHG=827>in " XBD=2157 XHG=2087 YBD=860 YHG=826>the " XBD=2337 XHG=2186 YBD=860 YHG=825>mental " XBD=2529 XHG=2364 YBD=871 YHG=825>hospitals" XBD=1412 XHG=1366 YBD=910 YHG=874>of " XBD=1778 XHG=1428 YBD=910 YHG=875>Ontario-which " XBD=1900 XHG=1796 YBD=909 YHG=876>have " XBD=1968 XHG=1915 YBD=909 YHG=887>an " XBD=2150 XHG=1982 YBD=920 YHG=886>average " XBD=2212 XHG=2166 YBD=909 YHG=874>of " XBD=2371 XHG=2229 YBD=916 YHG=876>16,000, " XBD=2528 XHG=2381 YBD=920 YHG=875>patients" XBD=1408 XHG=1365 YBD=958 YHG=924>in " XBD=1903 XHG=1437 YBD=964 YHG=924>residence-concludes " XBD=2086 XHG=1931 YBD=958 YHG=923>that &dquo; " XBD=2245 XHG=2104 YBD=971 YHG=924>taking " XBD=2331 XHG=2277 YBD=957 YHG=923>all " XBD=2423 XHG=2357 YBD=957 YHG=924>the " XBD=2545 XHG=2449 YBD=960 YHG=922>facts’" XBD=1564 XHG=1366 YBD=1018 YHG=973>together, " XBD=1779 XHG=1584 YBD=1014 YHG=973>however, " XBD=1847 XHG=1798 YBD=1007 YHG=961>it " XBD=1889 XHG=1855 YBD=1007 YHG=973>is " XBD=2121 XHG=1913 YBD=1019 YHG=960>probably " XBD=2214 XHG=2130 YBD=1007 YHG=972>safe " XBD=2275 XHG=2231 YBD=1007 YHG=976>to " XBD=2443 XHG=2294 YBD=1007 YHG=983>assume " XBD=2529 XHG=2458 YBD=1009 YHG=973>that" XBD=1408 XHG=1366 YBD=1056 YHG=1023>in " XBD=1709 XHG=1438 YBD=1067 YHG=1034>consequence " XBD=1782 XHG=1737 YBD=1057 YHG=1021>of " XBD=1879 XHG=1808 YBD=1056 YHG=1022>the " XBD=2034 XHG=1910 YBD=1057 YHG=1022>shock " XBD=2238 XHG=2064 YBD=1067 YHG=1022>therapy " XBD=2376 XHG=2269 YBD=1056 YHG=1022>work " XBD=2530 XHG=2407 YBD=1059 YHG=1022>carried" XBD=1441 XHG=1367 YBD=1107 YHG=1074>out " XBD=1605 XHG=1460 YBD=1117 YHG=1071>during " XBD=1694 XHG=1624 YBD=1105 YHG=1072>the " XBD=1830 XHG=1715 YBD=1116 YHG=1082>years " XBD=2024 XHG=1853 YBD=1106 YHG=1072>1938-41 " XBD=2160 XHG=2045 YBD=1105 YHG=1071>there " XBD=2281 XHG=2181 YBD=1105 YHG=1082>were " XBD=2344 XHG=2300 YBD=1105 YHG=1074>at " XBD=2456 XHG=2363 YBD=1106 YHG=1070>least " XBD=2529 XHG=2476 YBD=1108 YHG=1073>100" XBD=1547 XHG=1367 YBD=1166 YHG=1121>patients " XBD=1686 XHG=1568 YBD=1155 YHG=1120>fewer " XBD=1761 XHG=1708 YBD=1155 YHG=1132>on " XBD=1852 XHG=1781 YBD=1157 YHG=1121>the " XBD=1999 XHG=1873 YBD=1155 YHG=1120>books " XBD=2066 XHG=2022 YBD=1154 YHG=1119>of " XBD=2154 XHG=2084 YBD=1154 YHG=1120>the " XBD=2344 XHG=2177 YBD=1156 YHG=1120>Ontario " XBD=2529 XHG=2363 YBD=1167 YHG=1120>hospitals" XBD=1513 XHG=1367 YBD=1217 YHG=1170>during " XBD=1602 XHG=1532 YBD=1204 YHG=1169>the " XBD=1717 XHG=1622 YBD=1215 YHG=1181>year " XBD=1912 XHG=1739 YBD=1204 YHG=1170>1941-42 " XBD=2035 XHG=1932 YBD=1204 YHG=1169>than " XBD=2166 XHG=2052 YBD=1204 YHG=1169>there " XBD=2318 XHG=2186 YBD=1204 YHG=1170>would " XBD=2435 XHG=2336 YBD=1204 YHG=1170>have " XBD=2531 XHG=2453 YBD=1206 YHG=1170>been" XBD=1405 XHG=1366 YBD=1253 YHG=1214>if " XBD=1477 XHG=1423 YBD=1254 YHG=1230>no " XBD=1601 XHG=1503 YBD=1253 YHG=1219>such " XBD=1783 XHG=1626 YBD=1264 YHG=1218>specific " XBD=2029 XHG=1807 YBD=1253 YHG=1221>treatment " XBD=2135 XHG=2052 YBD=1254 YHG=1219>had " XBD=2260 XHG=2160 YBD=1253 YHG=1218>been " XBD=2438 XHG=2285 YBD=1265 YHG=1218>given.&dquo; " XBD=2530 XHG=2484 YBD=1255 YHG=1220>He" XBD=1454 XHG=1369 YBD=1303 YHG=1268>also " XBD=1598 XHG=1469 YBD=1303 YHG=1267>found " XBD=1705 XHG=1612 YBD=1302 YHG=1269>that " XBD=1907 XHG=1721 YBD=1302 YHG=1267>valuable " XBD=1967 XHG=1922 YBD=1302 YHG=1279>as " XBD=2052 XHG=1982 YBD=1302 YHG=1268>the " XBD=2235 XHG=2067 YBD=1302 YHG=1268>method " XBD=2283 XHG=2249 YBD=1301 YHG=1268>is " XBD=2362 XHG=2297 YBD=1303 YHG=1260>for " XBD=2530 XHG=2374 YBD=1304 YHG=1268>affective" XBD=1584 XHG=1368 YBD=1363 YHG=1318>psychoses " XBD=1646 XHG=1604 YBD=1352 YHG=1318>in " XBD=1830 XHG=1666 YBD=1363 YHG=1328>persons " XBD=1937 XHG=1850 YBD=1351 YHG=1317>first " XBD=2158 XHG=1958 YBD=1351 YHG=1317>admitted " XBD=2357 XHG=2179 YBD=1352 YHG=1318>between " XBD=2441 XHG=2376 YBD=1352 YHG=1318>the " XBD=2530 XHG=2459 YBD=1363 YHG=1312>ages" XBD=1414 XHG=1368 YBD=1401 YHG=1366>of " XBD=1483 XHG=1432 YBD=1401 YHG=1368>40 " XBD=1586 XHG=1506 YBD=1401 YHG=1367>and " XBD=1657 XHG=1609 YBD=1402 YHG=1368>59 " XBD=1807 XHG=1680 YBD=1412 YHG=1378>years, " XBD=1855 XHG=1833 YBD=1379 YHG=1365>&dquo; " XBD=1973 XHG=1874 YBD=1411 YHG=1377>very " XBD=2099 XHG=1992 YBD=1400 YHG=1365>little " XBD=2289 XHG=2121 YBD=1411 YHG=1369>support " XBD=2344 XHG=2311 YBD=1401 YHG=1367>is " XBD=2531 XHG=2365 YBD=1412 YHG=1367>provided" XBD=1430 XHG=1367 YBD=1451 YHG=1415>for " XBD=1522 XHG=1451 YBD=1450 YHG=1416>the " XBD=1656 XHG=1543 YBD=1457 YHG=1417>view, " XBD=1869 XHG=1678 YBD=1460 YHG=1415>formerly " XBD=2032 XHG=1888 YBD=1460 YHG=1415>widely " XBD=2157 XHG=2051 YBD=1455 YHG=1415>held, " XBD=2273 XHG=2180 YBD=1450 YHG=1415>that " XBD=2415 XHG=2294 YBD=1450 YHG=1416>shock " XBD=2529 XHG=2432 YBD=1452 YHG=1419>treat-" XBD=1482 XHG=1367 YBD=1500 YHG=1468>ment " XBD=1578 XHG=1506 YBD=1499 YHG=1466>has " XBD=1721 XHG=1603 YBD=1499 YHG=1464>value " XBD=1788 XHG=1744 YBD=1499 YHG=1466>in " XBD=2150 XHG=1812 YBD=1510 YHG=1464>schizophrenia.&dquo; " XBD=2331 XHG=2206 YBD=1499 YHG=1464>These " XBD=2531 XHG=2355 YBD=1500 YHG=1466>moderate" XBD=1618 XHG=1368 YBD=1549 YHG=1513>conclusions " XBD=1705 XHG=1639 YBD=1548 YHG=1525>are " XBD=1767 XHG=1725 YBD=1549 YHG=1514>in " XBD=1907 XHG=1788 YBD=1560 YHG=1514>sharp " XBD=2109 XHG=1929 YBD=1549 YHG=1516>contrast " XBD=2227 XHG=2128 YBD=1548 YHG=1514>with " XBD=2321 XHG=2251 YBD=1548 YHG=1514>the " XBD=2531 XHG=2342 YBD=1560 YHG=1514>optimistic" XBD=1609 XHG=1368 YBD=1598 YHG=1566>statements " XBD=1738 XHG=1622 YBD=1598 YHG=1563>made " XBD=1878 XHG=1751 YBD=1598 YHG=1563>about " XBD=1961 XHG=1891 YBD=1597 YHG=1563>the " XBD=2139 XHG=1974 YBD=1608 YHG=1562>efficacy " XBD=2199 XHG=2154 YBD=1597 YHG=1562>of " XBD=2357 XHG=2210 YBD=1597 YHG=1563>insulin " XBD=2447 XHG=2370 YBD=1598 YHG=1564>and " XBD=2529 XHG=2460 YBD=1598 YHG=1575>con." XBD=1528 XHG=1367 YBD=1647 YHG=1612>vulsion " XBD=1726 XHG=1541 YBD=1658 YHG=1612>therapy. " XBD=1831 XHG=1781 YBD=1647 YHG=1613>In " XBD=1926 XHG=1845 YBD=1657 YHG=1624>any " XBD=2029 XHG=1941 YBD=1646 YHG=1623>case " XBD=2081 XHG=2047 YBD=1647 YHG=1613>it " XBD=2212 XHG=2099 YBD=1647 YHG=1612>looks " XBD=2275 XHG=2232 YBD=1646 YHG=1623>as " XBD=2328 XHG=2293 YBD=1646 YHG=1611>if " XBD=2367 XHG=2344 YBD=1647 YHG=1625>a " XBD=2531 XHG=2384 YBD=1657 YHG=1612>planned" XBD=1621 XHG=1366 YBD=1707 YHG=1662>therapeutic " XBD=1885 XHG=1635 YBD=1707 YHG=1662>experiment " XBD=2031 XHG=1898 YBD=1696 YHG=1661>would " XBD=2153 XHG=2048 YBD=1696 YHG=1662>have " XBD=2283 XHG=2166 YBD=1697 YHG=1662>made " XBD=2322 XHG=2299 YBD=1697 YHG=1674>a " XBD=2463 XHG=2337 YBD=1697 YHG=1662>better " XBD=2529 XHG=2478 YBD=1706 YHG=1662>job" XBD=1413 XHG=1367 YBD=1745 YHG=1710>of " XBD=1482 XHG=1437 YBD=1745 YHG=1711>it. " XBD=1715 XHG=1537 YBD=1756 YHG=1711>Perhaps " XBD=1812 XHG=1742 YBD=1745 YHG=1711>the " XBD=2091 XHG=1839 YBD=1757 YHG=1712>therapeutic " XBD=2232 XHG=2118 YBD=1745 YHG=1711>trials " XBD=2479 XHG=2260 YBD=1746 YHG=1710>committee " XBD=2533 XHG=2501 YBD=1746 YHG=1711>of" XBD=1438 XHG=1366 YBD=1794 YHG=1760>the " XBD=1627 XHG=1456 YBD=1794 YHG=1759>Medical " XBD=1846 XHG=1645 YBD=1794 YHG=1760>Research " XBD=2030 XHG=1866 YBD=1795 YHG=1760>Council " XBD=2179 XHG=2048 YBD=1806 YHG=1760>might " XBD=2247 XHG=2197 YBD=1795 YHG=1760>be " XBD=2450 XHG=2269 YBD=1796 YHG=1760>invoked." XBD=1474 XHG=1417 YBD=1844 YHG=1809>At " XBD=1565 XHG=1495 YBD=1844 YHG=1810>the " XBD=1719 XHG=1587 YBD=1855 YHG=1809>Royal " XBD=2214 XHG=1739 YBD=1856 YHG=1809>Medico-Psychological " XBD=2477 XHG=2235 YBD=1844 YHG=1808>Association " XBD=2530 XHG=2493 YBD=1844 YHG=1821>on" XBD=1505 XHG=1365 YBD=1893 YHG=1859>March " XBD=1576 XHG=1530 YBD=1894 YHG=1861>10 " XBD=1668 XHG=1598 YBD=1893 YHG=1859>the " XBD=1850 XHG=1689 YBD=1905 YHG=1863>present " XBD=2005 XHG=1873 YBD=1894 YHG=1862>status " XBD=2071 XHG=2026 YBD=1893 YHG=1858>of " XBD=2310 XHG=2089 YBD=1905 YHG=1858>prefrontal " XBD=2531 XHG=2331 YBD=1904 YHG=1858>leucotomy" XBD=1447 XHG=1365 YBD=1943 YHG=1919>was " XBD=1688 XHG=1472 YBD=1943 YHG=1908>discussed. " XBD=1901 XHG=1743 YBD=1954 YHG=1908>Among " XBD=1995 XHG=1924 YBD=1943 YHG=1909>the " XBD=2299 XHG=2018 YBD=1955 YHG=1909>psychiatrists " XBD=2431 XHG=2322 YBD=1943 YHG=1909>there " XBD=2530 XHG=2452 YBD=1942 YHG=1919>were" XBD=1600 XHG=1366 YBD=1992 YHG=1958>differences " XBD=1679 XHG=1634 YBD=1992 YHG=1957>of " XBD=1873 XHG=1708 YBD=2004 YHG=1958>opinion " XBD=2032 XHG=1905 YBD=1993 YHG=1958>about " XBD=2119 XHG=2064 YBD=1993 YHG=1959>its " XBD=2270 XHG=2151 YBD=1992 YHG=1957>value " XBD=2394 XHG=2303 YBD=1993 YHG=1958>and’ " XBD=2531 XHG=2414 YBD=1992 YHG=1957>modus" XBD=1586 XHG=1366 YBD=2053 YHG=2008>operandi ; " XBD=1773 XHG=1627 YBD=2053 YHG=2019>among " XBD=1867 XHG=1796 YBD=2042 YHG=2008>the " XBD=2079 XHG=1891 YBD=2053 YHG=2019>surgeons " XBD=2230 XHG=2104 YBD=2043 YHG=2008>about " XBD=2323 XHG=2252 YBD=2042 YHG=2007>the " XBD=2531 XHG=2345 YBD=2052 YHG=2007>technique" XBD=1449 XHG=1366 YBD=2091 YHG=2057>and " XBD=1539 XHG=1468 YBD=2091 YHG=2057>the " XBD=1673 XHG=1559 YBD=2091 YHG=2057>risks. " XBD=1812 XHG=1728 YBD=2092 YHG=2058>But " XBD=1945 XHG=1832 YBD=2092 YHG=2058>there " XBD=2046 XHG=1965 YBD=2092 YHG=2068>was " XBD=2311 XHG=2067 YBD=2092 YHG=2056>substantial " XBD=2531 XHG=2332 YBD=2102 YHG=2058>agreement" XBD=1459 XHG=1365 YBD=2142 YHG=2107>that " XBD=1554 XHG=1484 YBD=2140 YHG=2107>the " XBD=1745 XHG=1579 YBD=2142 YHG=2107>method " XBD=1803 XHG=1769 YBD=2141 YHG=2107>is " XBD=1909 XHG=1828 YBD=2141 YHG=2106>still " XBD=2236 XHG=1934 YBD=2153 YHG=2106>experimental, " XBD=2353 XHG=2260 YBD=2141 YHG=2107>that " XBD=2408 XHG=2376 YBD=2141 YHG=2106>it " XBD=2531 XHG=2431 YBD=2140 YHG=2117>some-" XBD=1484 XHG=1364 YBD=2191 YHG=2156>times " XBD=1707 XHG=1512 YBD=2202 YHG=2156>produces " XBD=1934 XHG=1736 YBD=2191 YHG=2156>dramatic " XBD=2270 XHG=1962 YBD=2202 YHG=2157>improvement, " XBD=2391 XHG=2299 YBD=2190 YHG=2156>that " XBD=2456 XHG=2417 YBD=2190 YHG=2155>in " XBD=2532 XHG=2479 YBD=2190 YHG=2155>the" XBD=1495 XHG=1364 YBD=2240 YHG=2206>hands " XBD=1552 XHG=1508 YBD=2240 YHG=2205>of " XBD=1582 XHG=1558 YBD=2240 YHG=2218>a " XBD=1733 XHG=1593 YBD=2240 YHG=2205>skilled " XBD=2010 XHG=1742 YBD=2251 YHG=2205>neurological " XBD=2191 XHG=2020 YBD=2251 YHG=2218>surgeon " XBD=2232 XHG=2199 YBD=2240 YHG=2206>it " XBD=2274 XHG=2241 YBD=2240 YHG=2206>is " XBD=2355 XHG=2283 YBD=2239 YHG=2208>not " XBD=2531 XHG=2364 YBD=2240 YHG=2202>attended" XBD=1463 XHG=1363 YBD=2289 YHG=2255>with " XBD=1602 XHG=1489 YBD=2300 YHG=2258>great " XBD=1709 XHG=1626 YBD=2289 YHG=2255>risk " XBD=1777 XHG=1733 YBD=2289 YHG=2257>to " XBD=1883 XHG=1803 YBD=2296 YHG=2254>life, " XBD=1992 XHG=1910 YBD=2291 YHG=2255>and " XBD=2109 XHG=2016 YBD=2289 YHG=2255>that " XBD=2168 XHG=2133 YBD=2289 YHG=2255>it " XBD=2271 XHG=2197 YBD=2290 YHG=2266>can " XBD=2397 XHG=2295 YBD=2288 YHG=2254>have " XBD=2471 XHG=2420 YBD=2300 YHG=2254>by " XBD=2529 XHG=2491 YBD=2288 YHG=2264>no" XBD=1503 XHG=1363 YBD=2339 YHG=2315>means " XBD=1738 XHG=1527 YBD=2349 YHG=2303>negligible " XBD=1798 XHG=1755 YBD=2338 YHG=2303>ill " XBD=1973 XHG=1823 YBD=2338 YHG=2304>effects. " XBD=2098 XHG=2027 YBD=2339 YHG=2304>Dr. " XBD=2237 XHG=2119 YBD=2338 YHG=2305>ROLF " XBD=2531 XHG=2259 YBD=2339 YHG=2302>STROM-OLSE1" XBD=1466 XHG=1363 YBD=2399 YHG=2364>gave " XBD=1509 XHG=1485 YBD=2388 YHG=2365>a " XBD=1675 XHG=1529 YBD=2388 YHG=2354>candid " XBD=1866 XHG=1694 YBD=2388 YHG=2356>account " XBD=1930 XHG=1886 YBD=2388 YHG=2352>of " XBD=2103 XHG=1947 YBD=2388 YHG=2353>clinical " XBD=2294 XHG=2122 YBD=2399 YHG=2353>findings " XBD=2436 XHG=2313 YBD=2387 YHG=2352>which " XBD=2531 XHG=2452 YBD=2387 YHG=2361>were" XBD=1437 XHG=1362 YBD=2437 YHG=2406>not " XBD=1692 XHG=1468 YBD=2447 YHG=2403>reassuring " XBD=1768 XHG=1724 YBD=2437 YHG=2414>as " XBD=1843 XHG=1799 YBD=2437 YHG=2406>to " XBD=1945 XHG=1875 YBD=2437 YHG=2403>the " XBD=2078 XHG=1976 YBD=2437 YHG=2403>wide " XBD=2386 XHG=2109 YBD=2449 YHG=2401>applicability " XBD=2456 XHG=2416 YBD=2436 YHG=2401>of " XBD=2531 XHG=2479 YBD=2435 YHG=2401>the" XBD=1542 XHG=1362 YBD=2486 YHG=2452>method. " XBD=1670 XHG=1596 YBD=2485 YHG=2452>Mr. " XBD=1758 XHG=1713 YBD=2486 YHG=2452>F. " XBD=1863 XHG=1801 YBD=2486 YHG=2452>W. " XBD=2122 XHG=1906 YBD=2487 YHG=2452>WILLWAY " XBD=2247 XHG=2165 YBD=2486 YHG=2451>and " XBD=2365 XHG=2292 YBD=2485 YHG=2450>Mr. " XBD=2530 XHG=2406 YBD=2486 YHG=2451>WrYLIE" XBD=1621 XHG=1361 YBD=2535 YHG=2501>McKISSOCK " XBD=1855 XHG=1647 YBD=2535 YHG=2501>described " XBD=1984 XHG=1880 YBD=2535 YHG=2501>their " XBD=2232 XHG=2009 YBD=2546 YHG=2502>respective " XBD=2422 XHG=2258 YBD=2546 YHG=2500>surgical |>" XBD=2529 XHG=2444 YBD=2535 YHG=2499>tech." XBD=1518 XHG=1362 YBD=2596 YHG=2551>niques, " XBD=1616 XHG=1535 YBD=2584 YHG=2550>and " XBD=1704 XHG=1630 YBD=2585 YHG=2550>Mr. " XBD=1978 XHG=1720 YBD=2585 YHG=2550>McKISSOCK " XBD=2161 XHG=1992 YBD=2595 YHG=2551>pointed " XBD=2247 XHG=2175 YBD=2585 YHG=2553>out " XBD=2353 XHG=2261 YBD=2584 YHG=2550>that " XBD=2528 XHG=2368 YBD=2595 YHG=2549>epilepsy," XBD=1531 XHG=1362 YBD=2644 YHG=2600>aphasia " XBD=1631 XHG=1549 YBD=2633 YHG=2600>and " XBD=1927 XHG=1649 YBD=2633 YHG=2599>incontinence " XBD=1990 XHG=1947 YBD=2633 YHG=2599>of " XBD=2119 XHG=2005 YBD=2633 YHG=2600>urine " XBD=2240 XHG=2138 YBD=2633 YHG=2611>were " XBD=2529 XHG=2259 YBD=2644 YHG=2598>complications" XBD=1457 XHG=1362 YBD=2682 YHG=2649>that " XBD=1597 XHG=1479 YBD=2682 YHG=2647>could " XBD=1689 XHG=1617 YBD=2682 YHG=2651>not " XBD=1760 XHG=1711 YBD=2683 YHG=2649>be " XBD=1990 XHG=1781 YBD=2682 YHG=2648>dismissed " XBD=2055 XHG=2011 YBD=2682 YHG=2659>as " XBD=2228 XHG=2076 YBD=2693 YHG=2648>trifling " XBD=2290 XHG=2247 YBD=2681 YHG=2649>in " XBD=2529 XHG=2310 YBD=2693 YHG=2648>comparison" XBD=1462 XHG=1363 YBD=2731 YHG=2697>with " XBD=1560 XHG=1490 YBD=2731 YHG=2697>the " XBD=1740 XHG=1587 YBD=2732 YHG=2697>mental " XBD=1923 XHG=1776 YBD=2731 YHG=2697>illness. " XBD=2065 XHG=1994 YBD=2732 YHG=2697>Dr. " XBD=2150 XHG=2105 YBD=2731 YHG=2697>F. " XBD=2235 XHG=2190 YBD=2731 YHG=2698>L. " XBD=2414 XHG=2275 YBD=2732 YHG=2697>GOLLA " XBD=2528 XHG=2444 YBD=2731 YHG=2697>drev

" XBD=1637 XHG=1364 YBD=2791 YHG=2746>comparisons " XBD=1837 XHG=1657 YBD=2781 YHG=2746>between " XBD=1931 XHG=1861 YBD=2781 YHG=2746>the " XBD=2080 XHG=1956 YBD=2780 YHG=2746>tissue " XBD=2272 XHG=2104 YBD=2791 YHG=2746>damage " XBD=2338 XHG=2295 YBD=2780 YHG=2746>in " XBD=2529 XHG=2363 YBD=2781 YHG=2742>electrical" XBD=1601 XHG=1364 YBD=2829 YHG=2783>convulsion " XBD=1813 XHG=1639 YBD=2840 YHG=2796>therapy " XBD=1925 XHG=1845 YBD=2830 YHG=2796>and " XBD=2058 XHG=1964 YBD=2829 YHG=2796>that " XBD=2139 XHG=2097 YBD=2829 YHG=2796>in " XBD=2393 XHG=2176 YBD=2840 YHG=2794>prefrontal |>" XBD=2526 XHG=2424 YBD=2830 YHG=2795>leuco." XBD=1492 XHG=1362 YBD=2888 YHG=2847>tomy, " XBD=1602 XHG=1520 YBD=2878 YHG=2844>and " XBD=1686 XHG=1636 YBD=2878 YHG=2845>he " XBD=1959 XHG=1719 YBD=2889 YHG=2844>deprecated " XBD=2065 XHG=1994 YBD=2878 YHG=2845>the " XBD=2222 XHG=2102 YBD=2878 YHG=2845>static " XBD=2479 XHG=2259 YBD=2889 YHG=2845>conception " XBD=2530 XHG=2499 YBD=2879 YHG=2840>of" XBD=1541 XHG=1364 YBD=2927 YHG=2892>cerebral " XBD=1752 XHG=1567 YBD=2927 YHG=2892>function " XBD=1869 XHG=1775 YBD=2927 YHG=2894>that " XBD=1978 XHG=1895 YBD=2926 YHG=2903>sees " XBD=2045 XHG=2002 YBD=2926 YHG=2893>in " XBD=2144 XHG=2062 YBD=2927 YHG=2893>this " XBD=2371 XHG=2164 YBD=2938 YHG=2893>operation " XBD=2527 XHG=2388 YBD=2936 YHG=2893>nothing" XBD=1439 XHG=1363 YBD=2975 YHG=2941>but " XBD=1520 XHG=1467 YBD=2975 YHG=2953>an " XBD=1825 XHG=1550 YBD=2975 YHG=2941>irremediable " XBD=2030 XHG=1856 YBD=2976 YHG=2945>trauma. " XBD=2225 XHG=2100 YBD=2976 YHG=2941>Other " XBD=2436 XHG=2257 YBD=2986 YHG=2953>surgeons " XBD=2525 XHG=2463 YBD=2976 YHG=2940>and" XBD=1480 XHG=1363 YBD=3024 YHG=2990>other " XBD=1786 XHG=1505 YBD=3035 YHG=2990>psychiatrists " XBD=2065 XHG=1806 YBD=3024 YHG=2989>contributed " XBD=2127 XHG=2082 YBD=3025 YHG=2992>to " XBD=2173 XHG=2147 YBD=3024 YHG=3002>a " XBD=2406 XHG=2191 YBD=3025 YHG=2990>discussion " XBD=2560 XHG=2422 YBD=3025 YHG=2991>which" XBD=1593 XHG=1363 YBD=3073 YHG=3039>sometimes " XBD=1897 XHG=1611 YBD=3083 YHG=3038>intentionally " XBD=1988 XHG=1908 YBD=3072 YHG=3038>and " XBD=2230 XHG=2001 YBD=3073 YHG=3039>sometimes " XBD=2297 XHG=2242 YBD=3083 YHG=3039>by " XBD=2525 XHG=2310 YBD=3084 YHG=3039>implication" XBD=1601 XHG=1362 YBD=3121 YHG=3087>underlined " XBD=1694 XHG=1624 YBD=3121 YHG=3088>the " XBD=1938 XHG=1718 YBD=3131 YHG=3098>vagueness " XBD=2007 XHG=1963 YBD=3121 YHG=3086>of " XBD=2098 XHG=2027 YBD=3121 YHG=3088>the " XBD=2360 XHG=2121 YBD=3122 YHG=3087>indications " XBD=2455 XHG=2383 YBD=3122 YHG=3089>and " XBD=2525 XHG=2474 YBD=3123 YHG=3088>the" XBD=1535 XHG=1362 YBD=3179 YHG=3135>dubiety " XBD=1606 XHG=1560 YBD=3169 YHG=3135>of " XBD=1697 XHG=1627 YBD=3169 YHG=3136>the " XBD=1917 XHG=1722 YBD=3169 YHG=3135>rationale " XBD=2027 XHG=1945 YBD=3169 YHG=3135>and " XBD=2209 XHG=2051 YBD=3170 YHG=3135>results. " XBD=2524 XHG=2263 YBD=3181 YHG=3135>Psychological" XBD=1466 XHG=1362 YBD=3217 YHG=3185>tests " XBD=1586 XHG=1489 YBD=3227 YHG=3195>may " XBD=1658 XHG=1608 YBD=3218 YHG=3183>be " XBD=1779 XHG=1680 YBD=3217 YHG=3184>used " XBD=1845 XHG=1801 YBD=3217 YHG=3186>to " XBD=2006 XHG=1869 YBD=3217 YHG=3184>decide " XBD=2065 XHG=2030 YBD=3217 YHG=3182>if " XBD=2197 XHG=2083 YBD=3217 YHG=3185>there " XBD=2253 XHG=2219 YBD=3217 YHG=3183>is " XBD=2523 XHG=2276 YBD=3219 YHG=3183>deterioration" XBD=1470 XHG=1363 YBD=3265 YHG=3231>after " XBD=1562 XHG=1492 YBD=3266 YHG=3232>the " XBD=1807 XHG=1586 YBD=3276 YHG=3232>operation." XBD=1467 XHG=1416 YBD=3314 YHG=3280>In " XBD=1552 XHG=1480 YBD=3314 YHG=3291>our " XBD=1645 XHG=1565 YBD=3314 YHG=3279>last " XBD=1762 XHG=1657 YBD=3314 YHG=3279>issue " XBD=1845 XHG=1776 YBD=3314 YHG=3280>Dr. " XBD=2043 XHG=1861 YBD=3314 YHG=3280>HUTTON " XBD=2245 XHG=2056 YBD=3325 YHG=3280>reported " XBD=2309 XHG=2258 YBD=3314 YHG=3291>on " XBD=2368 XHG=2322 YBD=3315 YHG=3282>50 " XBD=2522 XHG=2380 YBD=3326 YHG=3281>patients" XBD=1525 XHG=1364 YBD=3363 YHG=3328>treated " XBD=1598 XHG=1541 YBD=3371 YHG=3328>by " XBD=1682 XHG=1612 YBD=3363 YHG=3329>the " XBD=1867 XHG=1699 YBD=3363 YHG=3329>method " XBD=1964 XHG=1883 YBD=3363 YHG=3329>and " XBD=2061 XHG=1979 YBD=3363 YHG=3340>was " XBD=2168 XHG=2078 YBD=3362 YHG=3328>able " XBD=2229 XHG=2184 YBD=3363 YHG=3331>to " XBD=2357 XHG=2246 YBD=3371 YHG=3329>point " XBD=2412 XHG=2372 YBD=3364 YHG=3332>to " XBD=2521 XHG=2426 YBD=3371 YHG=3339>many

1. Further Report on the 1938-1941 Shock Treated Cases in theOntario Hospitals. Prepared by the Division of Statistics,Ontario Department of Health, January, 1943.

405

" XBD=388 XHG=156 YBD=259 YHG=212>- encouraging " XBD=611 XHG=411 YBD=253 YHG=211>features ; " XBD=723 XHG=652 YBD=246 YHG=212>the " XBD=925 XHG=747 YBD=257 YHG=212>patients " XBD=1049 XHG=949 YBD=246 YHG=223>were " XBD=1247 XHG=1075 YBD=247 YHG=212>selected " XBD=1315 XHG=1271 YBD=246 YHG=224>a,s" XBD=284 XHG=157 YBD=307 YHG=262>having " XBD=400 XHG=308 YBD=307 YHG=272>poor " XBD=644 XHG=427 YBD=307 YHG=262>prognosis, " XBD=746 XHG=675 YBD=305 YHG=263>yet " XBD=845 XHG=774 YBD=295 YHG=261>the " XBD=1060 XHG=874 YBD=295 YHG=263>outcome " XBD=1169 XHG=1089 YBD=296 YHG=273>was " XBD=1312 XHG=1199 YBD=295 YHG=261>satis-" XBD=290 XHG=155 YBD=355 YHG=311>factory " XBD=349 XHG=310 YBD=344 YHG=310>in " XBD=394 XHG=371 YBD=344 YHG=321>a " XBD=686 XHG=417 YBD=344 YHG=308>considerable " XBD=1096 XHG=710 YBD=354 YHG=309>proportion-they " XBD=1186 XHG=1119 YBD=343 YHG=320>are " XBD=1312 XHG=1210 YBD=343 YHG=309>back" XBD=315 XHG=154 YBD=400 YHG=359>at work, " XBD=372 XHG=330 YBD=394 YHG=370>or " XBD=493 XHG=391 YBD=393 YHG=358>their " XBD=679 XHG=514 YBD=393 YHG=358>distress " XBD=747 XHG=702 YBD=392 YHG=357>of " XBD=877 XHG=764 YBD=392 YHG=357>mind " XBD=963 XHG=890 YBD=392 YHG=358>has " XBD=1083 XHG=982 YBD=392 YHG=358>been " XBD=1312 XHG=1097 YBD=392 YHG=357>alleviated" XBD=222 XHG=152 YBD=445 YHG=409>and " XBD=334 XHG=240 YBD=443 YHG=407>their " XBD=523 XHG=355 YBD=449 YHG=407>conduct " XBD=743 XHG=546 YBD=441 YHG=407>bettered. " XBD=998 XHG=798 YBD=451 YHG=406>Similarly |>" XBD=1090 XHG=1020 YBD=441 YHG=393>Dr. " XBD=1311 XHG=1115 YBD=440 YHG=407>FLEMING" XBD=222 XHG=153 YBD=494 YHG=458>and " XBD=309 XHG=243 YBD=492 YHG=455>Mr. MKissocA " XBD=740 XHG=604 YBD=501 YHG=458>report " XBD=859 XHG=767 YBD=490 YHG=455>that " XBD=930 XHG=885 YBD=490 YHG=455>of " XBD=1002 XHG=958 YBD=489 YHG=456>12 " XBD=1311 XHG=1031 YBD=489 YHG=454>melancholies|>" XBD=234 XHG=152 YBD=549 YHG=507>with " XBD=277 XHG=256 YBD=540 YHG=517>a " XBD=398 XHG=300 YBD=550 YHG=506>good " XBD=626 XHG=420 YBD=551 YHG=505>prognosis " XBD=673 XHG=652 YBD=539 YHG=506>7 " XBD=806 XHG=702 YBD=538 YHG=505>have " XBD=1045 XHG=832 YBD=538 YHG=504>recovered " XBD=1312 XHG=1072 YBD=549 YHG=503>completely" XBD=242 XHG=151 YBD=591 YHG=557>since " XBD=321 XHG=257 YBD=588 YHG=553>the " XBD=554 XHG=339 YBD=599 YHG=554>operation, " XBD=658 XHG=575 YBD=587 YHG=553>and " XBD=846 XHG=677 YBD=587 YHG=554>another " XBD=938 XHG=864 YBD=587 YHG=553>has " XBD=1095 XHG=958 YBD=587 YHG=553>shown " XBD=1309 XHG=1114 YBD=587 YHG=552>consider-" XBD=226 XHG=150 YBD=640 YHG=604>able " XBD=539 XHG=249 YBD=648 YHG=604>improvement. " XBD=636 XHG=595 YBD=635 YHG=602>It " XBD=796 XHG=664 YBD=637 YHG=601>would " XBD=934 XHG=828 YBD=636 YHG=612>seem " XBD=1065 XHG=961 YBD=636 YHG=601>from " XBD=1203 XHG=1091 YBD=635 YHG=602>these " XBD=1312 XHG=1231 YBD=636 YHG=598>and" XBD=249 XHG=149 YBD=689 YHG=654>other " XBD=417 XHG=270 YBD=697 YHG=655>reports " XBD=536 XHG=443 YBD=686 YHG=651>that " XBD=751 XHG=564 YBD=685 YHG=650>affective " XBD=986 XHG=778 YBD=692 YHG=651>disorders, " XBD=1058 XHG=1015 YBD=684 YHG=651>in " XBD=1214 XHG=1086 YBD=684 YHG=650>which " XBD=1311 XHG=1241 YBD=685 YHG=651>the" XBD=329 XHG=151 YBD=750 YHG=700>prognosis |>" XBD=435 XHG=345 YBD=735 YHG=701>is-in " XBD=534 XHG=452 YBD=745 YHG=711>any " XBD=643 XHG=553 YBD=734 YHG=711>case " XBD=715 XHG=662 YBD=734 YHG=711>on " XBD=802 XHG=733 YBD=734 YHG=700>the " XBD=990 XHG=821 YBD=746 YHG=711>average " XBD=1125 XHG=1008 YBD=746 YHG=700>good, " XBD=1240 XHG=1145 YBD=744 YHG=711>may " XBD=1311 XHG=1258 YBD=734 YHG=700>do" XBD=232 XHG=150 YBD=792 YHG=750>well, " XBD=316 XHG=248 YBD=785 YHG=750>but " XBD=420 XHG=332 YBD=785 YHG=750>that " XBD=588 XHG=436 YBD=795 YHG=749>typical " XBD=936 XHG=606 YBD=795 YHG=749>schizophrenics, " XBD=1166 XHG=955 YBD=795 YHG=749>especially " XBD=1229 XHG=1183 YBD=784 YHG=748>of " XBD=1310 XHG=1241 YBD=784 YHG=750>the" XBD=174 XHG=156 YBD=815 YHG=801>&dquo; " XBD=370 XHG=188 YBD=834 YHG=798>nuclear &dquo; " XBD=498 XHG=389 YBD=844 YHG=802>type, " XBD=573 XHG=521 YBD=833 YHG=799>do " XBD=668 XHG=595 YBD=833 YHG=802>not " XBD=808 XHG=688 YBD=844 YHG=798>profit " XBD=884 XHG=829 YBD=844 YHG=799>by " XBD=937 XHG=903 YBD=833 YHG=800>it " XBD=1001 XHG=957 YBD=833 YHG=811>as " XBD=1046 XHG=1021 YBD=833 YHG=811>a " XBD=1160 XHG=1065 YBD=834 YHG=799>rule.

Annotations

SIR JOHN LEDINGHAM’S RETIREMENT

" XBD=234 XHG=185 YBD=1075 YHG=1044>AT " XBD=309 XHG=248 YBD=1075 YHG=1044>the " XBD=403 XHG=332 YBD=1075 YHG=1045>end " XBD=468 XHG=429 YBD=1075 YHG=1044>of " XBD=560 XHG=483 YBD=1076 YHG=1045>this " XBD=712 XHG=576 YBD=1076 YHG=1045>month " XBD=786 XHG=729 YBD=1076 YHG=1045>Sir " XBD=912 XHG=809 YBD=1077 YHG=1045>John " XBD=1181 XHG=936 YBD=1085 YHG=1045>Ledingham, " XBD=1304 XHG=1199 YBD=1080 YHG=1046>FRS," XBD=209 XHG=148 YBD=1120 YHG=1089>will " XBD=319 XHG=223 YBD=1119 YHG=1088>hand " XBD=421 XHG=335 YBD=1120 YHG=1097>over " XBD=503 XHG=438 YBD=1120 YHG=1088>the " XBD=768 XHG=521 YBD=1129 YHG=1089>directorship " XBD=827 XHG=787 YBD=1120 YHG=1089>of " XBD=908 XHG=843 YBD=1121 YHG=1090>the " XBD=1048 XHG=925 YBD=1121 YHG=1089>Lister " XBD=1247 XHG=1066 YBD=1121 YHG=1090>Institute " XBD=1305 XHG=1264 YBD=1121 YHG=1092>to" XBD=200 XHG=146 YBD=1165 YHG=1134>Dr. " XBD=265 XHG=223 YBD=1164 YHG=1132>A. " XBD=334 XHG=289 YBD=1164 YHG=1132>N. " XBD=497 XHG=360 YBD=1173 YHG=1133>Drury, " XBD=645 XHG=523 YBD=1165 YHG=1133>FRS. " XBD=749 XHG=691 YBD=1164 YHG=1134>He " XBD=867 XHG=777 YBD=1165 YHG=1134>thus " XBD=1091 XHG=892 YBD=1165 YHG=1133>concludes " XBD=1168 XHG=1120 YBD=1165 YHG=1144>an " XBD=1304 XHG=1197 YBD=1165 YHG=1135>unin-" XBD=317 XHG=143 YBD=1217 YHG=1177>terrupted " XBD=459 XHG=331 YBD=1217 YHG=1177>period " XBD=514 XHG=475 YBD=1208 YHG=1178>of " XBD=671 XHG=530 YBD=1209 YHG=1179>service " XBD=808 XHG=687 YBD=1210 YHG=1178>which " XBD=947 XHG=825 YBD=1219 YHG=1178>began " XBD=1002 XHG=962 YBD=1209 YHG=1179>in " XBD=1179 XHG=1018 YBD=1219 YHG=1179>August, " XBD=1303 XHG=1201 YBD=1215 YHG=1180>1905," XBD=221 XHG=144 YBD=1253 YHG=1221>with " XBD=288 XHG=235 YBD=1252 YHG=1221>his " XBD=564 XHG=304 YBD=1261 YHG=1222>appointment " XBD=702 XHG=581 YBD=1253 YHG=1223>under " XBD=783 XHG=718 YBD=1253 YHG=1223>the " XBD=876 XHG=799 YBD=1254 YHG=1222>late " XBD=959 XHG=892 YBD=1254 YHG=1224>Dr. " XBD=1121 XHG=979 YBD=1264 YHG=1223>George " XBD=1245 XHG=1138 YBD=1254 YHG=1224>Dean " XBD=1303 XHG=1262 YBD=1254 YHG=1225>to" XBD=198 XHG=142 YBD=1296 YHG=1266>the " XBD=303 XHG=221 YBD=1296 YHG=1265>staff " XBD=365 XHG=327 YBD=1296 YHG=1266>of " XBD=454 XHG=389 YBD=1297 YHG=1266>the " XBD=605 XHG=480 YBD=1297 YHG=1275>serum " XBD=874 XHG=633 YBD=1306 YHG=1267>department " XBD=941 XHG=902 YBD=1297 YHG=1268>of " XBD=1032 XHG=966 YBD=1298 YHG=1267>the " XBD=1235 XHG=1058 YBD=1298 YHG=1268>institute " XBD=1302 XHG=1262 YBD=1298 YHG=1269>at" XBD=280 XHG=144 YBD=1341 YHG=1309>Elstree. " XBD=373 XHG=329 YBD=1340 YHG=1310>In " XBD=479 XHG=390 YBD=1341 YHG=1311>1906 " XBD=602 XHG=494 YBD=1341 YHG=1311>Dean " XBD=695 XHG=617 YBD=1341 YHG=1319>was " XBD=938 XHG=709 YBD=1342 YHG=1311>transferred " XBD=992 XHG=952 YBD=1342 YHG=1320>as " XBD=1104 XHG=1006 YBD=1342 YHG=1311>chief " XBD=1301 XHG=1119 YBD=1342 YHG=1311>bacterio-" XBD=237 XHG=142 YBD=1394 YHG=1353>logist " XBD=287 XHG=249 YBD=1384 YHG=1355>to " XBD=363 XHG=301 YBD=1385 YHG=1354>the " XBD=477 XHG=377 YBD=1385 YHG=1354>main " XBD=668 XHG=491 YBD=1385 YHG=1354>institute " XBD=731 XHG=682 YBD=1385 YHG=1365>on " XBD=897 XHG=747 YBD=1386 YHG=1355>Chelsea " XBD=1196 XHG=913 YBD=1386 YHG=1355>Embankment " XBD=1302 XHG=1209 YBD=1387 YHG=1353>with" XBD=352 XHG=142 YBD=1438 YHG=1397>Ledingham " XBD=421 XHG=381 YBD=1430 YHG=1407>as " XBD=508 XHG=450 YBD=1430 YHG=1390>his " XBD=732 XHG=538 YBD=1430 YHG=1399>assistant. " XBD=901 XHG=783 YBD=1430 YHG=1399>Three " XBD=1040 XHG=931 YBD=1439 YHG=1409>years " XBD=1165 XHG=1069 YBD=1430 YHG=1399>later " XBD=1302 XHG=1193 YBD=1431 YHG=1400>Dean" XBD=276 XHG=142 YBD=1474 YHG=1443>became " XBD=489 XHG=305 YBD=1483 YHG=1442>professor " XBD=562 XHG=523 YBD=1474 YHG=1444>of " XBD=804 XHG=595 YBD=1483 YHG=1444>pathology " XBD=876 XHG=838 YBD=1474 YHG=1443>in " XBD=975 XHG=910 YBD=1475 YHG=1444>the " XBD=1230 XHG=1009 YBD=1483 YHG=1442>University " XBD=1303 XHG=1263 YBD=1474 YHG=1443>of" XBD=326 XHG=140 YBD=1523 YHG=1486>Aberdeen, " XBD=428 XHG=354 YBD=1518 YHG=1488>and " XBD=689 XHG=454 YBD=1528 YHG=1488>Ledingham " XBD=809 XHG=716 YBD=1518 YHG=1488>took " XBD=894 XHG=835 YBD=1518 YHG=1488>his " XBD=1027 XHG=920 YBD=1528 YHG=1488>place " XBD=1131 XHG=1055 YBD=1519 YHG=1488>and " XBD=1244 XHG=1156 YBD=1519 YHG=1488>held " XBD=1301 XHG=1270 YBD=1518 YHG=1488>it" XBD=225 XHG=140 YBD=1562 YHG=1530>until " XBD=298 XHG=244 YBD=1563 YHG=1530>his " XBD=583 XHG=320 YBD=1571 YHG=1532>appointment " XBD=651 XHG=610 YBD=1563 YHG=1542>as " XBD=836 XHG=674 YBD=1563 YHG=1532>director " XBD=896 XHG=858 YBD=1562 YHG=1532>in " XBD=1105 XHG=922 YBD=1572 YHG=1532>January, " XBD=1235 XHG=1134 YBD=1568 YHG=1533>1931, " XBD=1301 XHG=1261 YBD=1563 YHG=1532>in" XBD=331 XHG=142 YBD=1607 YHG=1576>succession " XBD=394 XHG=355 YBD=1607 YHG=1578>to " XBD=477 XHG=422 YBD=1607 YHG=1576>Sir " XBD=653 XHG=504 YBD=1608 YHG=1576>Charles " XBD=831 XHG=679 YBD=1613 YHG=1576>Martin, " XBD=964 XHG=858 YBD=1608 YHG=1576>FRS." XBD=312 XHG=178 YBD=1661 YHG=1620>During " XBD=398 XHG=340 YBD=1651 YHG=1621>his " XBD=563 XHG=417 YBD=1652 YHG=1622>’tenure " XBD=635 XHG=596 YBD=1652 YHG=1621>of " XBD=739 XHG=667 YBD=1652 YHG=1631>one " XBD=809 XHG=770 YBD=1652 YHG=1621>of " XBD=906 XHG=841 YBD=1651 YHG=1621>the " XBD=1038 XHG=940 YBD=1651 YHG=1622>most " XBD=1301 XHG=1071 YBD=1660 YHG=1621>responsible" XBD=288 XHG=138 YBD=1696 YHG=1664>research " XBD=410 XHG=307 YBD=1704 YHG=1666>posts " XBD=470 XHG=431 YBD=1695 YHG=1664>in " XBD=558 XHG=491 YBD=1696 YHG=1665>the " XBD=735 XHG=580 YBD=1696 YHG=1664>domain " XBD=795 XHG=756 YBD=1695 YHG=1665>of " XBD=1036 XHG=815 YBD=1705 YHG=1664>preventive " XBD=1241 XHG=1058 YBD=1696 YHG=1665>medicine " XBD=1301 XHG=1260 YBD=1695 YHG=1665>in" XBD=202 XHG=138 YBD=1739 YHG=1708>this " XBD=390 XHG=225 YBD=1748 YHG=1710>country, " XBD=475 XHG=419 YBD=1740 YHG=1708>Sir " XBD=603 XHG=501 YBD=1740 YHG=1709>John " XBD=699 XHG=628 YBD=1740 YHG=1710>has " XBD=868 XHG=724 YBD=1749 YHG=1708>proved " XBD=1043 XHG=892 YBD=1739 YHG=1708>himself " XBD=1137 XHG=1068 YBD=1740 YHG=1710>not " XBD=1252 XHG=1162 YBD=1748 YHG=1708>only " XBD=1300 XHG=1277 YBD=1739 YHG=1718>a" XBD=275 XHG=138 YBD=1792 YHG=1752>capable " XBD=577 XHG=295 YBD=1784 YHG=1753>administrator " XBD=675 XHG=598 YBD=1784 YHG=1753>and " XBD=910 XHG=697 YBD=1793 YHG=1753>supervisor " XBD=971 XHG=932 YBD=1784 YHG=1753>of " XBD=1160 XHG=991 YBD=1784 YHG=1753>research " XBD=1221 XHG=1182 YBD=1783 YHG=1753>in " XBD=1300 XHG=1242 YBD=1784 YHG=1752>his" XBD=258 XHG=138 YBD=1828 YHG=1797>chosen " XBD=394 XHG=291 YBD=1828 YHG=1797>fields " XBD=500 XHG=429 YBD=1828 YHG=1797>but " XBD=616 XHG=537 YBD=1828 YHG=1797>also " XBD=703 XHG=653 YBD=1828 YHG=1807>an " XBD=864 XHG=740 YBD=1828 YHG=1797>active " XBD=1224 XHG=899 YBD=1836 YHG=1797>experimentalist " XBD=1300 XHG=1260 YBD=1827 YHG=1797>in" XBD=395 XHG=137 YBD=1881 YHG=1841>microbiology. " XBD=582 XHG=447 YBD=1872 YHG=1841>Before " XBD=690 XHG=624 YBD=1872 YHG=1842>the " XBD=808 XHG=730 YBD=1872 YHG=1851>war " XBD=888 XHG=850 YBD=1871 YHG=1841>of " XBD=1094 XHG=933 YBD=1872 YHG=1843>1914-18 " XBD=1182 XHG=1136 YBD=1871 YHG=1841>he " XBD=1300 XHG=1223 YBD=1872 YHG=1850>was" XBD=254 XHG=136 YBD=1925 YHG=1885>chiefly " XBD=441 XHG=266 YBD=1925 YHG=1885>occupied " XBD=491 XHG=452 YBD=1915 YHG=1885>in " XBD=722 XHG=504 YBD=1925 YHG=1885>serological " XBD=1032 XHG=735 YBD=1921 YHG=1885>studies-such, " XBD=1102 XHG=1044 YBD=1916 YHG=1885>for " XBD=1299 XHG=1114 YBD=1924 YHG=1885>example," XBD=170 XHG=136 YBD=1960 YHG=1939>as " XBD=297 XHG=197 YBD=1961 YHG=1929>those " XBD=375 XHG=328 YBD=1960 YHG=1939>on " XBD=471 XHG=406 YBD=1961 YHG=1930>the " XBD=736 XHG=503 YBD=1961 YHG=1929>mechanism " XBD=806 XHG=768 YBD=1960 YHG=1930>of " XBD=1231 XHG=836 YBD=1969 YHG=1929>phagocytosis-and " XBD=1301 XHG=1261 YBD=1960 YHG=1929>in" XBD=401 XHG=135 YBD=2014 YHG=1973>investigations " XBD=467 XHG=418 YBD=2004 YHG=1984>on " XBD=550 XHG=484 YBD=2005 YHG=1973>the " XBD=871 XHG=567 YBD=2013 YHG=1973>bacteriological " XBD=963 XHG=887 YBD=2004 YHG=1974>and " XBD=1301 XHG=981 YBD=2013 YHG=1973>epidemiological" XBD=266 XHG=136 YBD=2058 YHG=2019>aspects " XBD=320 XHG=282 YBD=2049 YHG=2018>of " XBD=399 XHG=335 YBD=2048 YHG=2018>the " XBD=578 XHG=416 YBD=2057 YHG=2018>typhoid " XBD=744 XHG=596 YBD=2053 YHG=2018>carrier, " XBD=784 XHG=763 YBD=2048 YHG=2027>a " XBD=949 XHG=801 YBD=2057 YHG=2017>subject " XBD=1006 XHG=966 YBD=2048 YHG=2019>to " XBD=1145 XHG=1023 YBD=2049 YHG=2017>which " XBD=1209 XHG=1161 YBD=2047 YHG=2017>he " XBD=1301 XHG=1224 YBD=2047 YHG=2026>was" XBD=196 XHG=136 YBD=2093 YHG=2071>one " XBD=257 XHG=221 YBD=2093 YHG=2063>of " XBD=345 XHG=280 YBD=2093 YHG=2061>the " XBD=451 XHG=370 YBD=2093 YHG=2061>first " XBD=622 XHG=479 YBD=2092 YHG=2061>British " XBD=917 XHG=651 YBD=2092 YHG=2061>contributors. " XBD=1028 XHG=971 YBD=2092 YHG=2061>He " XBD=1129 XHG=1060 YBD=2092 YHG=2060>has " XBD=1300 XHG=1160 YBD=2100 YHG=2060>always" XBD=216 XHG=136 YBD=2138 YHG=2106>been " XBD=360 XHG=232 YBD=2146 YHG=2106>keenly " XBD=580 XHG=376 YBD=2137 YHG=2106>interested " XBD=635 XHG=596 YBD=2136 YHG=2105>in " XBD=926 XHG=653 YBD=2145 YHG=2105>experimental " XBD=1206 XHG=940 YBD=2146 YHG=2105>haematology, " XBD=1301 XHG=1224 YBD=2135 YHG=2104>and" XBD=167 XHG=135 YBD=2181 YHG=2151>in " XBD=270 XHG=188 YBD=2181 YHG=2152>1914 " XBD=333 XHG=286 YBD=2181 YHG=2150>he " XBD=496 XHG=352 YBD=2190 YHG=2150>opened " XBD=537 XHG=516 YBD=2181 YHG=2160>a " XBD=640 XHG=556 YBD=2181 YHG=2159>new " XBD=732 XHG=657 YBD=2180 YHG=2150>line " XBD=790 XHG=751 YBD=2180 YHG=2150>of " XBD=960 XHG=807 YBD=2189 YHG=2150>inquiry " XBD=1031 XHG=978 YBD=2189 YHG=2150>by " XBD=1195 XHG=1049 YBD=2189 YHG=2149>finding " XBD=1300 XHG=1213 YBD=2179 YHG=2149>that" XBD=153 XHG=135 YBD=2224 YHG=2204>a " XBD=289 XHG=176 YBD=2226 YHG=2204>serum " XBD=497 XHG=314 YBD=2234 YHG=2194>prepared " XBD=578 XHG=524 YBD=2233 YHG=2195>by " XBD=847 XHG=602 YBD=2233 YHG=2194>immunising " XBD=965 XHG=872 YBD=2225 YHG=2194>with " XBD=1300 XHG=992 YBD=2233 YHG=2192>blood-platelets" XBD=199 XHG=133 YBD=2270 YHG=2248>was " XBD=382 XHG=222 YBD=2277 YHG=2238>capable, " XBD=456 XHG=408 YBD=2268 YHG=2248>on " XBD=663 XHG=481 YBD=2277 YHG=2238>injection " XBD=769 XHG=687 YBD=2268 YHG=2238>into " XBD=860 XHG=793 YBD=2268 YHG=2238>the " XBD=1026 XHG=884 YBD=2268 YHG=2237>animal " XBD=1192 XHG=1051 YBD=2276 YHG=2237>species " XBD=1299 XHG=1214 YBD=2277 YHG=2246>pro-" XBD=249 XHG=134 YBD=2323 YHG=2282>viding " XBD=376 XHG=262 YBD=2318 YHG=2282>them, " XBD=430 XHG=391 YBD=2312 YHG=2282>of " XBD=655 XHG=445 YBD=2321 YHG=2281>producing " XBD=695 XHG=673 YBD=2312 YHG=2291>a " XBD=905 XHG=712 YBD=2312 YHG=2281>condition " XBD=1060 XHG=922 YBD=2320 YHG=2280>closely " XBD=1301 XHG=1077 YBD=2320 YHG=2281>resembling" XBD=283 XHG=134 YBD=2366 YHG=2336>purpura " XBD=588 XHG=296 YBD=2366 YHG=2325>haemorrhagica " XBD=642 XHG=603 YBD=2356 YHG=2326>in " XBD=760 XHG=658 YBD=2356 YHG=2335>man. " XBD=858 XHG=812 YBD=2356 YHG=2325>In " XBD=938 XHG=872 YBD=2356 YHG=2325>the " XBD=1115 XHG=952 YBD=2356 YHG=2325>interval " XBD=1300 XHG=1130 YBD=2356 YHG=2325>between" XBD=190 XHG=134 YBD=2402 YHG=2371>the " XBD=277 XHG=207 YBD=2402 YHG=2373>two " XBD=390 XHG=296 YBD=2401 YHG=2380>wars " XBD=677 XHG=411 YBD=2401 YHG=2369>fundamental " XBD=841 XHG=699 YBD=2401 YHG=2369>studies " XBD=912 XHG=863 YBD=2400 YHG=2379>on " XBD=1077 XHG=933 YBD=2400 YHG=2369>viruses " XBD=1175 XHG=1098 YBD=2400 YHG=2369>and " XBD=1300 XHG=1195 YBD=2400 YHG=2369>virus" XBD=276 XHG=134 YBD=2446 YHG=2415>diseases " XBD=470 XHG=305 YBD=2454 YHG=2414>engaged " XBD=558 XHG=499 YBD=2444 YHG=2414>his " XBD=790 XHG=587 YBD=2445 YHG=2414>attention. " XBD=948 XHG=842 YBD=2445 YHG=2414>With " XBD=1043 XHG=977 YBD=2444 YHG=2413>the " XBD=1136 XHG=1074 YBD=2444 YHG=2414>aid " XBD=1205 XHG=1166 YBD=2444 YHG=2414>of " XBD=1300 XHG=1234 YBD=2445 YHG=2414>the" XBD=333 XHG=133 YBD=2499 YHG=2458>high-speed " XBD=587 XHG=362 YBD=2498 YHG=2458>centrifuges " XBD=714 XHG=621 YBD=2488 YHG=2458>then " XBD=934 XHG=748 YBD=2489 YHG=2457>available " XBD=1010 XHG=962 YBD=2488 YHG=2457>he " XBD=1114 XHG=1037 YBD=2488 YHG=2467>was " XBD=1229 XHG=1144 YBD=2489 YHG=2458>able " XBD=1298 XHG=1257 YBD=2488 YHG=2459>to" XBD=249 XHG=134 YBD=2533 YHG=2502>obtain " XBD=360 XHG=269 YBD=2541 YHG=2511>pure " XBD=622 XHG=383 YBD=2541 YHG=2502>suspensions " XBD=679 XHG=641 YBD=2532 YHG=2502>of " XBD=768 XHG=702 YBD=2532 YHG=2501>the " XBD=893 XHG=790 YBD=2533 YHG=2501>virus " XBD=1049 XHG=917 YBD=2532 YHG=2501>bodies " XBD=1106 XHG=1066 YBD=2532 YHG=2501>of " XBD=1299 XHG=1129 YBD=2533 YHG=2502>vaccinia" XBD=197 XHG=134 YBD=2576 YHG=2543>and " XBD=387 XHG=214 YBD=2585 YHG=2543>fowl-pox " XBD=488 XHG=413 YBD=2576 YHG=2546>and " XBD=549 XHG=508 YBD=2577 YHG=2547>to " XBD=688 XHG=570 YBD=2585 YHG=2555>prove " XBD=795 XHG=708 YBD=2576 YHG=2546>that " XBD=921 XHG=815 YBD=2576 YHG=2545>these " XBD=1093 XHG=947 YBD=2576 YHG=2545>minute " XBD=1299 XHG=1117 YBD=2577 YHG=2545>elements" XBD=214 XHG=133 YBD=2620 YHG=2598>were " XBD=269 XHG=232 YBD=2620 YHG=2590>in " XBD=395 XHG=288 YBD=2620 YHG=2589>truth " XBD=481 XHG=416 YBD=2620 YHG=2589>the " XBD=728 XHG=504 YBD=2629 YHG=2589>aetiological " XBD=892 XHG=748 YBD=2628 YHG=2591>agents. " XBD=1058 XHG=943 YBD=2621 YHG=2590>Later " XBD=1125 XHG=1078 YBD=2620 YHG=2590>he " XBD=1299 XHG=1147 YBD=2621 YHG=2589>studied" XBD=188 XHG=133 YBD=2664 YHG=2633>the " XBD=452 XHG=213 YBD=2673 YHG=2632>morphology " XBD=558 XHG=480 YBD=2664 YHG=2634>and " XBD=652 XHG=586 YBD=2663 YHG=2634>the " XBD=894 XHG=681 YBD=2664 YHG=2632>conditions " XBD=963 XHG=924 YBD=2664 YHG=2634>of " XBD=1137 XHG=989 YBD=2674 YHG=2634>growth " XBD=1205 XHG=1166 YBD=2664 YHG=2634>of " XBD=1299 XHG=1233 YBD=2664 YHG=2634>the" XBD=301 XHG=134 YBD=2716 YHG=2677>curiously " XBD=468 XHG=324 YBD=2708 YHG=2677>diverse " XBD=608 XHG=489 YBD=2708 YHG=2678>forms " XBD=671 XHG=632 YBD=2707 YHG=2677>of " XBD=716 XHG=693 YBD=2707 YHG=2686>a " XBD=857 XHG=739 YBD=2717 YHG=2686>group " XBD=921 XHG=881 YBD=2708 YHG=2678>of " XBD=1151 XHG=944 YBD=2717 YHG=2678>organisms " XBD=1299 XHG=1173 YBD=2709 YHG=2678>whose" XBD=227 XHG=133 YBD=2751 YHG=2722>exact " XBD=483 XHG=242 YBD=2760 YHG=2720>relationship " XBD=533 XHG=502 YBD=2751 YHG=2721>is " XBD=647 XHG=550 YBD=2752 YHG=2721>hard " XBD=705 XHG=664 YBD=2751 YHG=2723>to " XBD=846 XHG=725 YBD=2752 YHG=2720>define " XBD=940 XHG=864 YBD=2752 YHG=2722>and " XBD=1079 XHG=956 YBD=2753 YHG=2722>which " XBD=1159 XHG=1097 YBD=2752 YHG=2731>are " XBD=1298 XHG=1176 YBD=2761 YHG=2731>repre-" XBD=247 XHG=134 YBD=2795 YHG=2763>sented " XBD=312 XHG=262 YBD=2803 YHG=2764>by " XBD=392 XHG=327 YBD=2795 YHG=2764>the " XBD=536 XHG=408 YBD=2795 YHG=2765>causal " XBD=666 XHG=552 YBD=2805 YHG=2766>agent " XBD=722 XHG=683 YBD=2795 YHG=2765>of " XBD=1098 XHG=737 YBD=2805 YHG=2765>pleuropneumonia " XBD=1153 XHG=1115 YBD=2796 YHG=2765>of " XBD=1297 XHG=1169 YBD=2796 YHG=2765>cattle." XBD=217 XHG=171 YBD=2838 YHG=2808>As " XBD=324 XHG=230 YBD=2838 YHG=2808>chief " XBD=616 XHG=336 YBD=2849 YHG=2808>bacteriologist " XBD=708 XHG=631 YBD=2840 YHG=2809>and " XBD=895 XHG=722 YBD=2846 YHG=2809>director, " XBD=969 XHG=910 YBD=2843 YHG=2809>Sir " XBD=1085 XHG=983 YBD=2841 YHG=2809>John " XBD=1167 XHG=1098 YBD=2841 YHG=2810>has " XBD=1298 XHG=1181 YBD=2840 YHG=2810>taken" XBD=205 XHG=131 YBD=2890 YHG=2852>part " XBD=266 XHG=230 YBD=2882 YHG=2852>in " XBD=538 XHG=293 YBD=2892 YHG=2852>establishing " XBD=643 XHG=566 YBD=2883 YHG=2853>and " XBD=710 XHG=670 YBD=2884 YHG=2853>in " XBD=920 XHG=737 YBD=2893 YHG=2854>fostering " XBD=1013 XHG=947 YBD=2884 YHG=2854>the " XBD=1231 XHG=1040 YBD=2885 YHG=2853>activities " XBD=1299 XHG=1259 YBD=2884 YHG=2853>of" XBD=185 XHG=132 YBD=2925 YHG=2895>the " XBD=373 XHG=201 YBD=2925 YHG=2895>National " XBD=594 XHG=390 YBD=2926 YHG=2895>Collection " XBD=652 XHG=612 YBD=2927 YHG=2897>of " XBD=774 XHG=668 YBD=2936 YHG=2896>Type " XBD=989 XHG=792 YBD=2934 YHG=2897>Cultures ; " XBD=1069 XHG=1020 YBD=2927 YHG=2897>he " XBD=1178 XHG=1085 YBD=2927 YHG=2897>took " XBD=1298 XHG=1195 YBD=2936 YHG=2899>steps" XBD=164 XHG=132 YBD=2968 YHG=2940>to " XBD=303 XHG=188 YBD=2968 YHG=2940>create " XBD=353 XHG=330 YBD=2969 YHG=2948>a " XBD=622 XHG=380 YBD=2978 YHG=2939>department " XBD=690 XHG=651 YBD=2970 YHG=2940>of " XBD=934 XHG=717 YBD=2980 YHG=2937>biophysics " XBD=999 XHG=961 YBD=2970 YHG=2941>in " XBD=1093 XHG=1026 YBD=2970 YHG=2940>the " XBD=1297 XHG=1120 YBD=2971 YHG=2940>institute" XBD=276 XHG=131 YBD=3021 YHG=2981>through " XBD=360 XHG=296 YBD=3012 YHG=2981>the " XBD=572 XHG=379 YBD=3021 YHG=2983>provision " XBD=646 XHG=592 YBD=3022 YHG=2983>by " XBD=729 XHG=663 YBD=3014 YHG=2983>the " XBD=981 XHG=749 YBD=3016 YHG=2984>Rockefeller " XBD=1245 XHG=1001 YBD=3014 YHG=2984>Foundation " XBD=1299 XHG=1259 YBD=3013 YHG=2983>of" XBD=184 XHG=131 YBD=3054 YHG=3024>the " XBD=389 XHG=207 YBD=3065 YHG=3024>Svedberg " XBD=634 XHG=411 YBD=3066 YHG=3026>high-speed " XBD=866 XHG=658 YBD=3067 YHG=3028>centrifuge " XBD=966 XHG=889 YBD=3057 YHG=3027>and " XBD=1297 XHG=990 YBD=3066 YHG=3027>electrophoresis" XBD=354 XHG=132 YBD=3107 YHG=3068>equipment ; " XBD=464 XHG=388 YBD=3100 YHG=3069>and " XBD=530 XHG=482 YBD=3100 YHG=3070>he " XBD=617 XHG=547 YBD=3101 YHG=3070>has " XBD=837 XHG=635 YBD=3101 YHG=3071>witnessed " XBD=920 XHG=855 YBD=3101 YHG=3071>the " XBD=1074 XHG=939 YBD=3108 YHG=3070>steady " XBD=1239 XHG=1092 YBD=3110 YHG=3071>growth " XBD=1297 XHG=1258 YBD=3100 YHG=3070>of" XBD=184 XHG=130 YBD=3141 YHG=3110>the " XBD=350 XHG=206 YBD=3143 YHG=3111>various " XBD=543 XHG=373 YBD=3144 YHG=3114>research " XBD=763 XHG=570 YBD=3150 YHG=3109>divisions, " XBD=866 XHG=788 YBD=3145 YHG=3114>and " XBD=955 XHG=889 YBD=3144 YHG=3114>the " XBD=1083 XHG=980 YBD=3152 YHG=3113>early " XBD=1233 XHG=1108 YBD=3153 YHG=3116>stages " XBD=1297 XHG=1258 YBD=3144 YHG=3113>of" XBD=199 XHG=131 YBD=3185 YHG=3162>new " XBD=288 XHG=217 YBD=3185 YHG=3155>and " XBD=517 XHG=308 YBD=3194 YHG=3155>important " XBD=733 XHG=539 YBD=3188 YHG=3157>additions " XBD=793 XHG=753 YBD=3187 YHG=3159>to " XBD=1034 XHG=816 YBD=3196 YHG=3156>knowledge " XBD=1094 XHG=1055 YBD=3187 YHG=3157>in " XBD=1298 XHG=1115 YBD=3188 YHG=3157>bacterial" XBD=325 XHG=131 YBD=3237 YHG=3197>chemistry, " XBD=507 XHG=358 YBD=3238 YHG=3200>protein " XBD=748 XHG=542 YBD=3239 YHG=3200>chemistry " XBD=859 XHG=782 YBD=3231 YHG=3201>and " XBD=957 XHG=891 YBD=3230 YHG=3200>the " XBD=1223 XHG=991 YBD=3239 YHG=3200>application " XBD=1297 XHG=1257 YBD=3230 YHG=3200>of|>" XBD=271 XHG=130 YBD=3272 YHG=3240>efikeient " XBD=472 XHG=292 YBD=3273 YHG=3241>bacterial " XBD=667 XHG=494 YBD=3283 YHG=3244>antigens " XBD=732 XHG=690 YBD=3273 YHG=3253>as " XBD=1016 XHG=753 YBD=3282 YHG=3244>prophylactic " XBD=1183 XHG=1039 YBD=3282 YHG=3245>agents. " XBD=1296 XHG=1237 YBD=3273 YHG=3243>He" XBD=186 XHG=130 YBD=3314 YHG=3282>has " XBD=308 XHG=199 YBD=3315 YHG=3284>taken " XBD=379 XHG=322 YBD=3315 YHG=3285>his " XBD=464 XHG=393 YBD=3316 YHG=3285>full " XBD=587 XHG=478 YBD=3316 YHG=3286>share " XBD=643 XHG=603 YBD=3317 YHG=3286>of " XBD=723 XHG=657 YBD=3316 YHG=3286>the " XBD=841 XHG=737 YBD=3316 YHG=3286>work " XBD=895 XHG=857 YBD=3316 YHG=3286>of " XBD=1042 XHG=910 YBD=3325 YHG=3287>expert " XBD=1295 XHG=1059 YBD=3316 YHG=3286>committees" XBD=232 XHG=130 YBD=3357 YHG=3327>under " XBD=308 XHG=245 YBD=3358 YHG=3328>the " XBD=460 XHG=322 YBD=3358 YHG=3328>former " XBD=591 XHG=475 YBD=3360 YHG=3329>Local " XBD=865 XHG=608 YBD=3359 YHG=3329>Government " XBD=1020 XHG=881 YBD=3363 YHG=3329>Board, " XBD=1103 XHG=1037 YBD=3359 YHG=3328>the " XBD=1295 XHG=1119 YBD=3366 YHG=3328>Ministry" XBD=161 XHG=130 YBD=3400 YHG=3370>of " XBD=319 XHG=177 YBD=3406 YHG=3370>Health, " XBD=403 XHG=338 YBD=3402 YHG=3371>the " XBD=581 XHG=421 YBD=3402 YHG=3372>London " XBD=752 XHG=600 YBD=3410 YHG=3372>County " XBD=936 XHG=771 YBD=3407 YHG=3371>Council, " XBD=1032 XHG=955 YBD=3402 YHG=3371>and " XBD=1116 XHG=1050 YBD=3401 YHG=3372>the " XBD=1295 XHG=1135 YBD=3401 YHG=3371>Medical" XBD=295 XHG=131 YBD=3445 YHG=3412>Research " XBD=472 XHG=309 YBD=3446 YHG=3414>Council. " XBD=603 XHG=524 YBD=3445 YHG=3415>The " XBD=891 XHG=617 YBD=3453 YHG=3414>encyclopaedic " XBD=1045 XHG=905 YBD=3453 YHG=3415>System " XBD=1099 XHG=1059 YBD=3453 YHG=3414>of " XBD=1292 XHG=1111 YBD=3444 YHG=3414>Bacterio-" XBD=193 XHG=129 YBD=3498 YHG=3456>logy " XBD=404 XHG=209 YBD=3497 YHG=3458>sponsored " XBD=472 XHG=420 YBD=3498 YHG=3459>by " XBD=551 XHG=486 YBD=3488 YHG=3458>the " XBD=682 XHG=567 YBD=3488 YHG=3457>latter " XBD=801 XHG=698 YBD=3495 YHG=3457>body " XBD=915 XHG=818 YBD=3487 YHG=3466>owes " XBD=1043 XHG=932 YBD=3487 YHG=3457>much " XBD=1100 XHG=1062 YBD=3486 YHG=3456>of " XBD=1165 XHG=1115 YBD=3487 YHG=3457>its " XBD=1293 XHG=1180 YBD=3487 YHG=3457>value

" XBD=1414 XHG=1374 YBD=244 YHG=214>to " XBD=1486 XHG=1428 YBD=244 YHG=213>his " XBD=1676 XHG=1500 YBD=244 YHG=213>editorial " XBD=1772 XHG=1689 YBD=243 YHG=222>care " XBD=1862 XHG=1786 YBD=243 YHG=212>and " XBD=1961 XHG=1876 YBD=243 YHG=211>skill " XBD=2051 XHG=1975 YBD=242 YHG=211>and " XBD=2104 XHG=2064 YBD=242 YHG=212>to " XBD=2175 XHG=2118 YBD=242 YHG=211>his " XBD=2273 XHG=2190 YBD=243 YHG=221>own " XBD=2569 XHG=2287 YBD=244 YHG=211>contributions" XBD=1452 XHG=1376 YBD=287 YHG=257>and " XBD=1579 XHG=1470 YBD=288 YHG=257>those " XBD=1638 XHG=1598 YBD=287 YHG=257>of " XBD=1720 XHG=1655 YBD=287 YHG=257>the " XBD=1924 XHG=1739 YBD=287 YHG=256>members " XBD=1983 XHG=1943 YBD=286 YHG=256>of " XBD=2057 XHG=1999 YBD=286 YHG=255>his " XBD=2176 XHG=2075 YBD=286 YHG=255>staff." XBD=1482 XHG=1425 YBD=331 YHG=300>Sir " XBD=1610 XHG=1506 YBD=331 YHG=301>John " XBD=1902 XHG=1635 YBD=340 YHG=300>Ledingham’s " XBD=2069 XHG=1926 YBD=330 YHG=299>friends " XBD=2169 XHG=2093 YBD=330 YHG=299>and " XBD=2333 XHG=2194 YBD=330 YHG=299>former " XBD=2569 XHG=2358 YBD=340 YHG=300>colleagues" XBD=1500 XHG=1374 YBD=375 YHG=344>whose " XBD=1617 XHG=1512 YBD=376 YHG=345>work " XBD=1699 XHG=1630 YBD=375 YHG=344>has " XBD=1901 XHG=1713 YBD=375 YHG=344>benefited " XBD=1967 XHG=1915 YBD=384 YHG=344>by " XBD=2037 XHG=1979 YBD=374 YHG=343>his " XBD=2173 XHG=2052 YBD=374 YHG=342>sound " XBD=2319 XHG=2186 YBD=374 YHG=343>advice " XBD=2409 XHG=2333 YBD=374 YHG=344>and " XBD=2569 XHG=2422 YBD=384 YHG=343>helpful" XBD=1610 XHG=1374 YBD=428 YHG=388>suggestions " XBD=1714 XHG=1638 YBD=420 YHG=388>will " XBD=1834 XHG=1741 YBD=420 YHG=388>wish " XBD=1942 XHG=1863 YBD=419 YHG=388>him " XBD=1994 XHG=1971 YBD=419 YHG=398>a " XBD=2196 XHG=2021 YBD=428 YHG=388>pleasant " XBD=2444 XHG=2224 YBD=418 YHG=387>retirement " XBD=2568 XHG=2473 YBD=419 YHG=388>with" XBD=1653 XHG=1375 YBD=471 YHG=433>opportunities " XBD=1732 XHG=1674 YBD=463 YHG=433>for " XBD=1975 XHG=1753 YBD=473 YHG=433>continuing " XBD=2061 XHG=1995 YBD=464 YHG=433>the " XBD=2292 XHG=2080 YBD=463 YHG=432>researches " XBD=2354 XHG=2313 YBD=462 YHG=433>to " XBD=2498 XHG=2375 YBD=463 YHG=431>which " XBD=2568 XHG=2519 YBD=463 YHG=432>he" XBD=1443 XHG=1374 YBD=507 YHG=475>has " XBD=1715 XHG=1467 YBD=516 YHG=477>unsparingly " XBD=1904 XHG=1739 YBD=508 YHG=477>devoted " XBD=1988 XHG=1928 YBD=509 YHG=477>his " XBD=2138 XHG=2013 YBD=509 YHG=477>active " XBD=2238 XHG=2161 YBD=507 YHG=476>life.

CANCER TREATMENT IN SOUTH WALES

|>|>" XBD=1587 XHG=1424 YBD=636 YHG=605>BEFORE " XBD=1694 XHG=1627 YBD=636 YHG=605>the " XBD=1807 XHG=1729 YBD=636 YHG=615>war " XBD=1867 XHG=1844 YBD=636 YHG=615>a " XBD=2054 XHG=1904 YBD=637 YHG=606>scheme " XBD=2167 XHG=2089 YBD=637 YHG=606>had " XBD=2375 XHG=2204 YBD=638 YHG=606>received " XBD=2567 XHG=2412 YBD=646 YHG=606>general" XBD=1559 XHG=1375 YBD=689 YHG=649>approval " XBD=1616 XHG=1574 YBD=680 YHG=650>to |>" XBD=1790 XHG=1632 YBD=689 YHG=649>provide " XBD=1864 XHG=1805 YBD=680 YHG=650>for " XBD=1945 XHG=1879 YBD=681 YHG=650>the " XBD=2167 XHG=1960 YBD=682 YHG=652>treatment " XBD=2224 XHG=2184 YBD=681 YHG=650>of " XBD=2371 XHG=2238 YBD=682 YHG=660>cancer " XBD=2426 XHG=2386 YBD=681 YHG=650>in " XBD=2566 XHG=2442 YBD=681 YHG=650>South" XBD=1499 XHG=1374 YBD=724 YHG=693>Wales " XBD=1601 XHG=1525 YBD=724 YHG=693>and " XBD=1852 XHG=1627 YBD=725 YHG=693>Monmouth " XBD=1916 XHG=1878 YBD=724 YHG=693>in " XBD=2144 XHG=1941 YBD=726 YHG=694>fulfilment " XBD=2209 XHG=2170 YBD=726 YHG=695>of " XBD=2299 XHG=2233 YBD=726 YHG=695>the " XBD=2467 XHG=2324 YBD=726 YHG=695>Cancer " XBD=2565 XHG=2490 YBD=725 YHG=694>Act" XBD=1480 XHG=1377 YBD=769 YHG=738>1939. " XBD=1653 XHG=1532 YBD=769 YHG=737>There " XBD=1751 XHG=1674 YBD=769 YHG=747>was " XBD=1815 XHG=1774 YBD=769 YHG=740>to " XBD=1886 XHG=1839 YBD=768 YHG=738>be " XBD=1931 XHG=1909 YBD=769 YHG=747>a " XBD=2299 XHG=1953 YBD=779 YHG=738>radiotherapeutic " XBD=2499 XHG=2321 YBD=770 YHG=739>institute " XBD=2565 XHG=2522 YBD=770 YHG=740>at|>" XBD=1515 XHG=1373 YBD=812 YHG=781>Sardiff " XBD=1660 XHG=1537 YBD=821 YHG=781>Royal " XBD=1894 XHG=1682 YBD=821 YHG=782>Infirmary, " XBD=2008 XHG=1914 YBD=813 YHG=782>with " XBD=2074 XHG=2030 YBD=813 YHG=783>52 " XBD=2187 XHG=2095 YBD=814 YHG=782>beds " XBD=2285 XHG=2208 YBD=814 YHG=784>and " XBD=2355 XHG=2305 YBD=814 YHG=783>all " XBD=2563 XHG=2375 YBD=821 YHG=783>services ;" XBD=1431 XHG=1372 YBD=857 YHG=825>for " XBD=1536 XHG=1459 YBD=857 YHG=825>this " XBD=1631 XHG=1565 YBD=857 YHG=826>the " XBD=1876 XHG=1659 YBD=857 YHG=826>architect’s " XBD=2012 XHG=1903 YBD=866 YHG=825>plans " XBD=2117 XHG=2033 YBD=857 YHG=819>had " XBD=2240 XHG=2145 YBD=858 YHG=827>been " XBD=2465 XHG=2267 YBD=867 YHG=828>prepared, " XBD=2564 XHG=2496 YBD=858 YHG=827>the" XBD=1570 XHG=1372 YBD=910 YHG=879>necessary " XBD=1680 XHG=1588 YBD=901 YHG=870>staff " XBD=1853 XHG=1698 YBD=901 YHG=870>decided " XBD=1921 XHG=1872 YBD=901 YHG=879>on " XBD=2016 XHG=1939 YBD=901 YHG=871>and " XBD=2099 XHG=2033 YBD=901 YHG=871>the " XBD=2198 XHG=2117 YBD=902 YHG=872>cost " XBD=2431 XHG=2217 YBD=902 YHG=871>estimated. " XBD=2563 XHG=2483 YBD=902 YHG=871>The" XBD=1448 XHG=1369 YBD=946 YHG=924>war " XBD=1662 XHG=1469 YBD=954 YHG=914>naturally " XBD=1821 XHG=1684 YBD=946 YHG=912>caused " XBD=1966 XHG=1844 YBD=954 YHG=914>delay, " XBD=2066 XHG=1989 YBD=946 YHG=915>and " XBD=2197 XHG=2086 YBD=946 YHG=915>the &dquo; " XBD=2422 XHG=2214 YBD=955 YHG=916>appointed " XBD=2560 XHG=2444 YBD=956 YHG=916>day &dquo;" XBD=1491 XHG=1369 YBD=991 YHG=959>under " XBD=1570 XHG=1505 YBD=990 YHG=959>the " XBD=1649 XHG=1586 YBD=990 YHG=961>act " XBD=1741 XHG=1664 YBD=990 YHG=968>was " XBD=1828 XHG=1756 YBD=999 YHG=960>put " XBD=1896 XHG=1843 YBD=990 YHG=959>off " XBD=2007 XHG=1909 YBD=990 YHG=959>from " XBD=2112 XHG=2021 YBD=999 YHG=969>year " XBD=2167 XHG=2127 YBD=990 YHG=961>to " XBD=2285 XHG=2182 YBD=999 YHG=969>year. " XBD=2444 XHG=2336 YBD=997 YHG=960>Now, " XBD=2561 XHG=2460 YBD=992 YHG=960>how-" XBD=1468 XHG=1369 YBD=1040 YHG=1013>ever, " XBD=1536 XHG=1488 YBD=1034 YHG=1013>an " XBD=1723 XHG=1554 YBD=1043 YHG=1005>attempt " XBD=1771 XHG=1740 YBD=1034 YHG=1004>is " XBD=1900 XHG=1788 YBD=1043 YHG=1003>being " XBD=2027 XHG=1916 YBD=1034 YHG=1004>made " XBD=2085 XHG=2044 YBD=1034 YHG=1005>to " XBD=2212 XHG=2103 YBD=1043 YHG=1004>bring " XBD=2294 XHG=2228 YBD=1035 YHG=1004>the " XBD=2460 XHG=2311 YBD=1035 YHG=1004>scheme " XBD=2560 XHG=2477 YBD=1035 YHG=1005>into" XBD=1492 XHG=1369 YBD=1088 YHG=1048>being, " XBD=1555 XHG=1532 YBD=1078 YHG=1057>a " XBD=1812 XHG=1592 YBD=1088 YHG=1050>temporary " XBD=2020 XHG=1849 YBD=1088 YHG=1047>building " XBD=2125 XHG=2056 YBD=1079 YHG=1047>has " XBD=2257 XHG=2162 YBD=1079 YHG=1048>been " XBD=2480 XHG=2294 YBD=1088 YHG=1048>provided " XBD=2560 XHG=2518 YBD=1080 YHG=1052>at|>" XBD=1617 XHG=1368 YBD=1124 YHG=1091>Whitchurch " XBD=1733 XHG=1635 YBD=1123 YHG=1092>EMS " XBD=1942 XHG=1754 YBD=1131 YHG=1091>Hospital, " XBD=2051 XHG=1960 YBD=1123 YHG=1102>near " XBD=2219 XHG=2068 YBD=1128 YHG=1091>Cardiff, " XBD=2315 XHG=2238 YBD=1123 YHG=1092>and " XBD=2381 XHG=2330 YBD=1123 YHG=1093>its " XBD=2562 XHG=2398 YBD=1132 YHG=1092>therapy" XBD=1577 XHG=1368 YBD=1176 YHG=1138>apparatus " XBD=1637 XHG=1606 YBD=1167 YHG=1136>is " XBD=1752 XHG=1668 YBD=1167 YHG=1136>due. " XBD=1990 XHG=1804 YBD=1167 YHG=1136>Members " XBD=2059 XHG=2019 YBD=1167 YHG=1136>of " XBD=2152 XHG=2085 YBD=1167 YHG=1137>the " XBD=2363 XHG=2181 YBD=1167 YHG=1136>National " XBD=2561 XHG=2393 YBD=1168 YHG=1137>Radium" XBD=1616 XHG=1368 YBD=1212 YHG=1180>Commission " XBD=1763 XHG=1644 YBD=1220 YHG=1180>lately " XBD=1928 XHG=1789 YBD=1213 YHG=1180>visited " XBD=2033 XHG=1956 YBD=1211 YHG=1180>this " XBD=2232 XHG=2061 YBD=1220 YHG=1180>building " XBD=2337 XHG=2259 YBD=1211 YHG=1180>and " XBD=2561 XHG=2364 YBD=1212 YHG=1181>conferred" XBD=1458 XHG=1365 YBD=1256 YHG=1225>with " XBD=1541 XHG=1474 YBD=1256 YHG=1225>the " XBD=1776 XHG=1557 YBD=1256 YHG=1224>committee " XBD=1831 XHG=1793 YBD=1255 YHG=1224>of " XBD=1913 XHG=1847 YBD=1255 YHG=1224>the " XBD=2079 XHG=1930 YBD=1255 YHG=1224>radium " XBD=2236 XHG=2097 YBD=1260 YHG=1226>centre, " XBD=2332 XHG=2255 YBD=1255 YHG=1224>and " XBD=2447 XHG=2349 YBD=1256 YHG=1224>later " XBD=2561 XHG=2465 YBD=1255 YHG=1225>with" XBD=1684 XHG=1365 YBD=1308 YHG=1269>representatives " XBD=1749 XHG=1710 YBD=1298 YHG=1268>of " XBD=1871 XHG=1774 YBD=1299 YHG=1268>local " XBD=2120 XHG=1896 YBD=1299 YHG=1268>authorities " XBD=2223 XHG=2146 YBD=1298 YHG=1268>and " XBD=2388 XHG=2248 YBD=1299 YHG=1268>others. " XBD=2561 XHG=2440 YBD=1299 YHG=1267>There" XBD=1440 XHG=1363 YBD=1343 YHG=1322>was " XBD=1675 XHG=1457 YBD=1352 YHG=1313>unanimity " XBD=1810 XHG=1692 YBD=1345 YHG=1313>about " XBD=1892 XHG=1827 YBD=1342 YHG=1312>the " XBD=2073 XHG=1908 YBD=1351 YHG=1321>urgency " XBD=2129 XHG=2090 YBD=1342 YHG=1311>of " XBD=2370 XHG=2143 YBD=1351 YHG=1311>proceeding " XBD=2478 XHG=2383 YBD=1341 YHG=1311>with " XBD=2561 XHG=2494 YBD=1342 YHG=1311>the" XBD=1514 XHG=1365 YBD=1387 YHG=1357>scheme " XBD=1572 XHG=1531 YBD=1387 YHG=1365>as " XBD=1648 XHG=1587 YBD=1387 YHG=1356>far " XBD=1705 XHG=1664 YBD=1387 YHG=1365>as " XBD=1788 XHG=1721 YBD=1386 YHG=1356>the " XBD=1880 XHG=1802 YBD=1386 YHG=1365>war " XBD=2036 XHG=1897 YBD=1391 YHG=1355>allows, " XBD=2130 XHG=2055 YBD=1385 YHG=1355>and " XBD=2213 XHG=2146 YBD=1385 YHG=1355>the " XBD=2335 XHG=2228 YBD=1386 YHG=1355>three " XBD=2560 XHG=2351 YBD=1395 YHG=1354>voluntary" XBD=1548 XHG=1363 YBD=1440 YHG=1400>hospitals " XBD=1655 XHG=1578 YBD=1431 YHG=1400>and " XBD=1815 XHG=1685 YBD=1430 YHG=1400>eleven local " XBD=2191 XHG=1968 YBD=1430 YHG=1399>authorities " XBD=2561 XHG=2219 YBD=1430 YHG=1399>involved-those" XBD=1403 XHG=1364 YBD=1476 YHG=1445>of " XBD=1612 XHG=1418 YBD=1484 YHG=1445>Newport, " XBD=1784 XHG=1632 YBD=1480 YHG=1444>Cardiff, " XBD=1988 XHG=1803 YBD=1480 YHG=1443>Swansea, " XBD=2177 XHG=2006 YBD=1483 YHG=1443>Merthyr " XBD=2268 XHG=2193 YBD=1474 YHG=1443>and " XBD=2399 XHG=2285 YBD=1475 YHG=1452>seven " XBD=2560 XHG=2415 YBD=1484 YHG=1445>county" XBD=1642 XHG=1362 YBD=1520 YHG=1489>councils-are " XBD=1900 XHG=1664 YBD=1528 YHG=1488>considering " XBD=2067 XHG=1920 YBD=1519 YHG=1488>details. " XBD=2197 XHG=2118 YBD=1519 YHG=1488>The " XBD=2314 XHG=2217 YBD=1518 YHG=1488>local " XBD=2561 XHG=2334 YBD=1522 YHG=1487>authorities" XBD=1461 XHG=1362 YBD=1564 YHG=1534>have " XBD=1624 XHG=1488 YBD=1573 YHG=1533>agreed " XBD=1691 XHG=1650 YBD=1563 YHG=1534>to " XBD=1844 XHG=1717 YBD=1572 YHG=1534>report " XBD=2024 XHG=1871 YBD=1573 YHG=1532>quickly " XBD=2090 XHG=2050 YBD=1563 YHG=1534>to " XBD=2182 XHG=2116 YBD=1563 YHG=1532>the " XBD=2336 XHG=2207 YBD=1564 YHG=1532>Welsh " XBD=2490 XHG=2361 YBD=1563 YHG=1531>Board " XBD=2560 XHG=2520 YBD=1563 YHG=1533>of" XBD=1519 XHG=1365 YBD=1614 YHG=1577>Health, and " XBD=1712 XHG=1646 YBD=1608 YHG=1577>the " XBD=1956 XHG=1736 YBD=1617 YHG=1579>temporary " XBD=2151 XHG=1980 YBD=1617 YHG=1576>building " XBD=2205 XHG=2174 YBD=1608 YHG=1577>is " XBD=2270 XHG=2229 YBD=1607 YHG=1578>to " XBD=2343 XHG=2296 YBD=1607 YHG=1576>be " XBD=2558 XHG=2368 YBD=1617 YHG=1576>enlarged." XBD=1441 XHG=1362 YBD=1652 YHG=1622>The " XBD=1546 XHG=1464 YBD=1652 YHG=1622>first " XBD=1838 XHG=1569 YBD=1661 YHG=1622>appointment " XBD=1973 XHG=1862 YBD=1652 YHG=1622>made " XBD=2070 XHG=1993 YBD=1652 YHG=1621>will " XBD=2139 XHG=2090 YBD=1652 YHG=1620>be " XBD=2247 XHG=2160 YBD=1652 YHG=1621>that " XBD=2311 XHG=2271 YBD=1651 YHG=1621>of " XBD=2355 XHG=2332 YBD=1651 YHG=1630>a " XBD=2560 XHG=2377 YBD=1652 YHG=1620>full-time" XBD=1658 XHG=1360 YBD=1705 YHG=1665>radiotherapist " XBD=1722 XHG=1684 YBD=1696 YHG=1666>of " XBD=1836 XHG=1745 YBD=1704 YHG=1665>high " XBD=2107 XHG=1859 YBD=1705 YHG=1664>professional " XBD=2268 XHG=2131 YBD=1696 YHG=1666>status.

BLOOD OXYGEN LEVELS AFTER BIRTH

" XBD=1454 XHG=1411 YBD=1818 YHG=1788>IT " XBD=1506 XHG=1475 YBD=1818 YHG=1788>is " XBD=1718 XHG=1526 YBD=1828 YHG=1788>generally " XBD=1873 XHG=1738 YBD=1827 YHG=1788>agreed " XBD=1980 XHG=1892 YBD=1819 YHG=1788>that " XBD=2041 XHG=1999 YBD=1819 YHG=1790>at " XBD=2164 XHG=2061 YBD=1818 YHG=1787>birth " XBD=2250 XHG=2184 YBD=1819 YHG=1788>the " XBD=2424 XHG=2271 YBD=1819 YHG=1787>arterial " XBD=2558 XHG=2442 YBD=1819 YHG=1788>blood" XBD=1401 XHG=1362 YBD=1863 YHG=1832>of " XBD=1488 XHG=1421 YBD=1862 YHG=1831>the " XBD=1624 XHG=1508 YBD=1871 YHG=1831>baby, " XBD=1681 XHG=1639 YBD=1862 YHG=1841>as " XBD=1898 XHG=1702 YBD=1862 YHG=1832>measured " XBD=1958 XHG=1918 YBD=1862 YHG=1832>in " XBD=2044 XHG=1977 YBD=1863 YHG=1832>the " XBD=2257 XHG=2064 YBD=1863 YHG=1831>umbilical " XBD=2356 XHG=2269 YBD=1863 YHG=1832>vein " XBD=2503 XHG=2377 YBD=1869 YHG=1831>blood, " XBD=2557 XHG=2525 YBD=1863 YHG=1833>is" XBD=1560 XHG=1361 YBD=1907 YHG=1875>saturated " XBD=1680 XHG=1587 YBD=1915 YHG=1876>only " XBD=1746 XHG=1706 YBD=1906 YHG=1877>to " XBD=1894 XHG=1775 YBD=1907 YHG=1876>about " XBD=2012 XHG=1923 YBD=1918 YHG=1878>50% " XBD=2091 XHG=2052 YBD=1907 YHG=1876>of " XBD=2176 XHG=2126 YBD=1908 YHG=1876>its " XBD=2558 XHG=2215 YBD=1917 YHG=1876>oxygen-carrying" XBD=1551 XHG=1362 YBD=1960 YHG=1920>capacity, " XBD=1736 XHG=1568 YBD=1951 YHG=1920>whereas " XBD=1798 XHG=1758 YBD=1951 YHG=1919>in " XBD=1888 XHG=1821 YBD=1951 YHG=1920>the " XBD=2018 XHG=1911 YBD=1952 YHG=1920>adult " XBD=2108 XHG=2041 YBD=1952 YHG=1921>the " XBD=2423 XHG=2131 YBD=1961 YHG=1920>corresponding " XBD=2557 XHG=2439 YBD=1961 YHG=1920>figure" XBD=1393 XHG=1361 YBD=1995 YHG=1964>is " XBD=1531 XHG=1411 YBD=1994 YHG=1964>about " XBD=1662 XHG=1556 YBD=2006 YHG=1965>95%. " XBD=1833 XHG=1713 YBD=1995 YHG=1964>There " XBD=1927 XHG=1858 YBD=1996 YHG=1965>has " XBD=2048 XHG=1953 YBD=1996 YHG=1965>been " XBD=2171 XHG=2073 YBD=1996 YHG=1965>little " XBD=2375 XHG=2197 YBD=1996 YHG=1965>evidence " XBD=2442 XHG=2402 YBD=1997 YHG=1965>of " XBD=2554 XHG=2466 YBD=1996 YHG=1965>how" XBD=1518 XHG=1363 YBD=2048 YHG=2007>quickly " XBD=1621 XHG=1541 YBD=2039 YHG=1996>the " XBD=1810 XHG=1632 YBD=2039 YHG=2008>newborn " XBD=1937 XHG=1834 YBD=2048 YHG=2009>baby " XBD=2133 XHG=1961 YBD=2040 YHG=2009>achieves " XBD=2271 XHG=2157 YBD=2040 YHG=2009>the &dquo; " XBD=2435 XHG=2287 YBD=2040 YHG=2009>adult &dquo; " XBD=2558 XHG=2460 YBD=2040 YHG=2009>level" XBD=1438 XHG=1361 YBD=2083 YHG=2051>and " XBD=1524 XHG=1458 YBD=2091 YHG=2053>yet " XBD=1622 XHG=1544 YBD=2083 YHG=2052>this " XBD=1785 XHG=1643 YBD=2093 YHG=2052>change " XBD=1836 XHG=1805 YBD=2084 YHG=2053>is " XBD=1927 XHG=1857 YBD=2084 YHG=2062>one " XBD=1987 XHG=1948 YBD=2084 YHG=2053>of " XBD=2072 XHG=2005 YBD=2085 YHG=2053>the " XBD=2192 XHG=2093 YBD=2085 YHG=2055>most " XBD=2389 XHG=2212 YBD=2085 YHG=2053>essential " XBD=2554 XHG=2408 YBD=2093 YHG=2053>adjust-" XBD=1487 XHG=1362 YBD=2127 YHG=2097>ments " XBD=1563 XHG=1523 YBD=2127 YHG=2097>of " XBD=1663 XHG=1597 YBD=2128 YHG=2097>the " XBD=1877 XHG=1697 YBD=2128 YHG=2097>neonatal " XBD=2043 XHG=1900 YBD=2138 YHG=2097>period. " XBD=2152 XHG=2113 YBD=2129 YHG=2097>C. " XBD=2224 XHG=2178 YBD=2129 YHG=2097>A. " XBD=2376 XHG=2252 YBD=2129 YHG=2098>Smith " XBD=2478 XHG=2402 YBD=2129 YHG=2098>and " XBD=2552 XHG=2505 YBD=2132 YHG=2097>E." XBD=1518 XHG=1364 YBD=2180 YHG=2140>Kaplan " XBD=1651 XHG=1552 YBD=2172 YHG=2141>have " XBD=1951 XHG=1686 YBD=2173 YHG=2142>endeavoured " XBD=2025 XHG=1985 YBD=2173 YHG=2144>to " XBD=2200 XHG=2061 YBD=2182 YHG=2142>supply " XBD=2311 XHG=2233 YBD=2173 YHG=2142>this " XBD=2556 XHG=2345 YBD=2173 YHG=2142>evidence " XBD=2556 XHG=2542 YBD=2163 YHG=2146>1." XBD=1531 XHG=1360 YBD=2225 YHG=2184>working " XBD=1645 XHG=1551 YBD=2216 YHG=2185>with " XBD=1691 XHG=1668 YBD=2216 YHG=2195>a " XBD=1870 XHG=1713 YBD=2217 YHG=2186>method " XBD=2068 XHG=1890 YBD=2226 YHG=2186>whereby " XBD=2203 XHG=2088 YBD=2217 YHG=2186>blood " XBD=2341 XHG=2224 YBD=2217 YHG=2185>taken " XBD=2484 XHG=2362 YBD=2217 YHG=2186>under " XBD=2557 XHG=2506 YBD=2216 YHG=2185>oil" XBD=1460 XHG=1360 YBD=2259 YHG=2228>from " XBD=1543 XHG=1477 YBD=2260 YHG=2229>the " XBD=1718 XHG=1561 YBD=2261 YHG=2229>infant’s " XBD=1819 XHG=1735 YBD=2261 YHG=2230>heel " XBD=1911 XHG=1834 YBD=2262 YHG=2240>was " XBD=2032 XHG=1927 YBD=2266 YHG=2230>used, " XBD=2073 XHG=2051 YBD=2260 YHG=2239>a " XBD=2246 XHG=2090 YBD=2260 YHG=2230>method " XBD=2394 XHG=2263 YBD=2261 YHG=2229>shown " XBD=2452 XHG=2411 YBD=2260 YHG=2232>to " XBD=2556 XHG=2469 YBD=2269 YHG=2229>give" XBD=1498 XHG=1360 YBD=2304 YHG=2273>results " XBD=1748 XHG=1523 YBD=2313 YHG=2273>practically " XBD=1948 XHG=1764 YBD=2307 YHG=2274>identical " XBD=2061 XHG=1967 YBD=2305 YHG=2274>with " XBD=2239 XHG=2086 YBD=2305 YHG=2273>arterial " XBD=2451 XHG=2262 YBD=2313 YHG=2275>puncture " XBD=2554 XHG=2476 YBD=2315 YHG=2273>and" XBD=1553 XHG=1360 YBD=2357 YHG=2317>requiring " XBD=1660 XHG=1570 YBD=2357 YHG=2316>only |>" XBD=1736 XHG=1678 YBD=2349 YHG=2318>0.2 " XBD=1860 XHG=1754 YBD=2349 YHG=2328>c.cm. " XBD=1918 XHG=1879 YBD=2349 YHG=2318>of " XBD=2060 XHG=1933 YBD=2352 YHG=2317>blood. " XBD=2144 XHG=2109 YBD=2348 YHG=2317>A " XBD=2271 XHG=2160 YBD=2349 YHG=2317>series " XBD=2328 XHG=2289 YBD=2348 YHG=2316>of " XBD=2391 XHG=2345 YBD=2347 YHG=2318>36 " XBD=2557 XHG=2408 YBD=2349 YHG=2309>normal" XBD=1506 XHG=1360 YBD=2393 YHG=2361>infants " XBD=1556 XHG=1516 YBD=2392 YHG=2361>in " XBD=1634 XHG=1568 YBD=2393 YHG=2361>the " XBD=1796 XHG=1650 YBD=2394 YHG=2362>Boston " XBD=2181 XHG=1806 YBD=2403 YHG=2361>Lying-in-Hospital " XBD=2286 XHG=2190 YBD=2393 YHG=2371>were " XBD=2555 XHG=2298 YBD=2402 YHG=2361>investigated" XBD=1402 XHG=1361 YBD=2436 YHG=2407>at " XBD=1605 XHG=1422 YBD=2437 YHG=2406>intervals " XBD=1666 XHG=1626 YBD=2437 YHG=2407>of " XBD=1707 XHG=1688 YBD=2437 YHG=2409>8 " XBD=1841 XHG=1727 YBD=2437 YHG=2407>hours " XBD=1902 XHG=1862 YBD=2437 YHG=2408>to " XBD=1970 XHG=1927 YBD=2437 YHG=2408>14 " XBD=2109 XHG=1990 YBD=2445 YHG=2406>days ; " XBD=2183 XHG=2144 YBD=2436 YHG=2406>in " XBD=2364 XHG=2204 YBD=2437 YHG=2405>another " XBD=2495 XHG=2383 YBD=2437 YHG=2406>series " XBD=2557 XHG=2516 YBD=2437 YHG=2406>of" XBD=1404 XHG=1362 YBD=2480 YHG=2451>31 " XBD=1562 XHG=1417 YBD=2481 YHG=2450>infants " XBD=1642 XHG=1575 YBD=2481 YHG=2450>the " XBD=1803 XHG=1656 YBD=2490 YHG=2460>oxygen " XBD=1970 XHG=1815 YBD=2481 YHG=2451>content " XBD=2021 XHG=1982 YBD=2480 YHG=2449>of " XBD=2100 XHG=2034 YBD=2480 YHG=2449>the " XBD=2224 XHG=2110 YBD=2480 YHG=2450>blood " XBD=2274 XHG=2234 YBD=2480 YHG=2450>in " XBD=2350 XHG=2284 YBD=2480 YHG=2449>the " XBD=2556 XHG=2361 YBD=2481 YHG=2449>umbilical" XBD=1517 XHG=1360 YBD=2525 YHG=2494>arteries " XBD=1620 XHG=1543 YBD=2524 YHG=2494>and " XBD=1732 XHG=1645 YBD=2525 YHG=2495>vein " XBD=1799 XHG=1758 YBD=2524 YHG=2495>at " XBD=1928 XHG=1824 YBD=2524 YHG=2493>birth " XBD=2020 XHG=1944 YBD=2525 YHG=2502>was " XBD=2257 XHG=2047 YBD=2530 YHG=2493>measured, " XBD=2351 XHG=2275 YBD=2524 YHG=2493>and " XBD=2419 XHG=2377 YBD=2524 YHG=2495>at " XBD=2553 XHG=2445 YBD=2525 YHG=2490>short" XBD=1542 XHG=1359 YBD=2569 YHG=2538>intervals " XBD=1791 XHG=1570 YBD=2569 YHG=2537>afterwards " XBD=1853 XHG=1820 YBD=2573 YHG=2538>2, " XBD=1904 XHG=1883 YBD=2567 YHG=2538>3 " XBD=1973 XHG=1931 YBD=2567 YHG=2546>or " XBD=2022 XHG=1999 YBD=2567 YHG=2538>4 " XBD=2196 XHG=2048 YBD=2568 YHG=2536>further " XBD=2429 XHG=2222 YBD=2576 YHG=2537>specimens " XBD=2554 XHG=2456 YBD=2569 YHG=2547>were" XBD=1541 XHG=1360 YBD=2612 YHG=2581>obtained " XBD=1674 XHG=1573 YBD=2612 YHG=2581>from " XBD=1776 XHG=1709 YBD=2612 YHG=2581>the " XBD=2011 XHG=1812 YBD=2611 YHG=2580>heel-the " XBD=2129 XHG=2047 YBD=2611 YHG=2580>first " XBD=2316 XHG=2165 YBD=2620 YHG=2581>usually " XBD=2394 XHG=2353 YBD=2612 YHG=2582>at " XBD=2553 XHG=2432 YBD=2612 YHG=2581>about" XBD=1405 XHG=1360 YBD=2657 YHG=2626>30 " XBD=1595 XHG=1430 YBD=2656 YHG=2626>minutes " XBD=1690 XHG=1618 YBD=2655 YHG=2625>but " XBD=1753 XHG=1713 YBD=2655 YHG=2625>in " XBD=1881 XHG=1778 YBD=2655 YHG=2633>some " XBD=1947 XHG=1906 YBD=2654 YHG=2625>at " XBD=2017 XHG=1976 YBD=2654 YHG=2626>15 " XBD=2207 XHG=2043 YBD=2655 YHG=2624>minutes " XBD=2274 XHG=2231 YBD=2655 YHG=2634>or " XBD=2432 XHG=2297 YBD=2656 YHG=2633>sooner " XBD=2555 XHG=2455 YBD=2656 YHG=2626>after" XBD=1474 XHG=1358 YBD=2700 YHG=2669>birth. " XBD=1572 XHG=1527 YBD=2699 YHG=2669>In " XBD=1715 XHG=1611 YBD=2699 YHG=2677>some " XBD=1954 XHG=1752 YBD=2703 YHG=2667>instances, " XBD=2070 XHG=1991 YBD=2703 YHG=2668>too, " XBD=2234 XHG=2110 YBD=2707 YHG=2668>X-ray " XBD=2551 XHG=2271 YBD=2700 YHG=2668>examinations" XBD=1455 XHG=1357 YBD=2743 YHG=2720>were " XBD=1582 XHG=1470 YBD=2743 YHG=2712>made " XBD=1638 XHG=1597 YBD=2742 YHG=2713>to " XBD=1772 XHG=1655 YBD=2742 YHG=2711>check " XBD=1853 XHG=1786 YBD=2741 YHG=2711>the " XBD=2000 XHG=1869 YBD=2750 YHG=2710>degree " XBD=2056 XHG=2016 YBD=2741 YHG=2711>of " XBD=2278 XHG=2070 YBD=2750 YHG=2712>expansion " XBD=2333 XHG=2294 YBD=2743 YHG=2713>of " XBD=2414 XHG=2347 YBD=2743 YHG=2712>the " XBD=2552 XHG=2429 YBD=2752 YHG=2712>lungs." XBD=1438 XHG=1359 YBD=2787 YHG=2756>The " XBD=1533 XHG=1451 YBD=2787 YHG=2756>first " XBD=1663 XHG=1553 YBD=2795 YHG=2755>point " XBD=1770 XHG=1684 YBD=2785 YHG=2755>that " XBD=1955 XHG=1791 YBD=2793 YHG=2763>emerges " XBD=2067 XHG=1968 YBD=2785 YHG=2754>from " XBD=2162 XHG=2086 YBD=2786 YHG=2755>this " XBD=2279 XHG=2174 YBD=2787 YHG=2755>work " XBD=2330 XHG=2299 YBD=2787 YHG=2756>is " XBD=2438 XHG=2350 YBD=2786 YHG=2756>that " XBD=2553 XHG=2458 YBD=2788 YHG=2756>with" XBD=1424 XHG=1358 YBD=2831 YHG=2800>the " XBD=1572 XHG=1453 YBD=2839 YHG=2809>group " XBD=1643 XHG=1603 YBD=2830 YHG=2799>of " XBD=1815 XHG=1672 YBD=2829 YHG=2799>infants " XBD=1884 XHG=1844 YBD=2828 YHG=2798>in " XBD=1979 XHG=1913 YBD=2829 YHG=2797>the " XBD=2089 XHG=2007 YBD=2830 YHG=2798>first " XBD=2140 XHG=2120 YBD=2828 YHG=2799>2 " XBD=2293 XHG=2169 YBD=2831 YHG=2799>weeks " XBD=2362 XHG=2322 YBD=2831 YHG=2800>of " XBD=2456 XHG=2390 YBD=2831 YHG=2800>life " XBD=2552 XHG=2485 YBD=2830 YHG=2800>the" XBD=1539 XHG=1358 YBD=2874 YHG=2843>neonatal " XBD=1671 XHG=1556 YBD=2874 YHG=2842>blood " XBD=1765 XHG=1688 YBD=2873 YHG=2852>was " XBD=1895 XHG=1783 YBD=2881 YHG=2841>fairly " XBD=1991 XHG=1908 YBD=2873 YHG=2843>well " XBD=2255 XHG=2004 YBD=2882 YHG=2844>oxygenated. " XBD=2371 XHG=2292 YBD=2875 YHG=2844>The " XBD=2551 XHG=2390 YBD=2883 YHG=2852>average" XBD=1416 XHG=1356 YBD=2917 YHG=2887>for " XBD=1506 XHG=1440 YBD=2917 YHG=2887>the " XBD=1644 XHG=1523 YBD=2917 YHG=2886>whole " XBD=1715 XHG=1671 YBD=2916 YHG=2887>36 " XBD=1809 XHG=1732 YBD=2916 YHG=2895>was " XBD=1940 XHG=1836 YBD=2926 YHG=2887>93%, " XBD=2042 XHG=1966 YBD=2917 YHG=2886>and " XBD=2132 XHG=2066 YBD=2918 YHG=2887>the " XBD=2270 XHG=2155 YBD=2927 YHG=2896>range " XBD=2339 XHG=2296 YBD=2918 YHG=2889>82 " XBD=2398 XHG=2357 YBD=2917 YHG=2889>to " XBD=2549 XHG=2421 YBD=2928 YHG=2888>100%." XBD=1408 XHG=1360 YBD=2961 YHG=2930>Of " XBD=1622 XHG=1424 YBD=2960 YHG=2930>the whole " XBD=1750 XHG=1639 YBD=2959 YHG=2929>series " XBD=1814 XHG=1770 YBD=2959 YHG=2929>23 " XBD=1959 XHG=1834 YBD=2971 YHG=2930>(64%) " XBD=2053 XHG=1976 YBD=2960 YHG=2930>had " XBD=2223 XHG=2071 YBD=2962 YHG=2930>arterial " XBD=2311 XHG=2237 YBD=2970 YHG=2931>(i.e. " XBD=2550 XHG=2326 YBD=2968 YHG=2931>cutaneous)" XBD=1472 XHG=1357 YBD=3004 YHG=2973>blood " XBD=1589 XHG=1495 YBD=3003 YHG=2972>with " XBD=1669 XHG=1619 YBD=3002 YHG=2981>an " XBD=1842 XHG=1694 YBD=3011 YHG=2981>oxygen " XBD=1963 XHG=1865 YBD=3008 YHG=2972>level " XBD=2026 XHG=1985 YBD=3005 YHG=2982>as " XBD=2140 XHG=2050 YBD=3013 YHG=2974>high " XBD=2206 XHG=2164 YBD=3005 YHG=2983>as " XBD=2272 XHG=2230 YBD=3004 YHG=2984>or " XBD=2428 XHG=2294 YBD=3013 YHG=2974>higher " XBD=2550 XHG=2453 YBD=3003 YHG=2973>than

the " XBD=1590 XHG=1440 YBD=3046 YHG=3015>lowest " XBD=1744 XHG=1635 YBD=3046 YHG=3015>adult " XBD=1891 XHG=1783 YBD=3046 YHG=3015>level. " XBD=2004 XHG=1960 YBD=3048 YHG=3017>In " XBD=2100 XHG=2035 YBD=3048 YHG=3017>the " XBD=2270 XHG=2132 YBD=3048 YHG=3017>second " XBD=2425 XHG=2300 YBD=3051 YHG=3017>series, " XBD=2550 XHG=2455 YBD=3046 YHG=3015>with" XBD=1672 XHG=1358 YBD=3090 YHG=3059>determinations " XBD=1815 XHG=1704 YBD=3090 YHG=3059>made " XBD=1981 XHG=1845 YBD=3101 YHG=3059>during " XBD=2075 XHG=2010 YBD=3091 YHG=3060>the " XBD=2182 XHG=2100 YBD=3090 YHG=3060>first " XBD=2320 XHG=2212 YBD=3095 YHG=3061>hour, |>" XBD=2477 XHG=2352 YBD=3099 YHG=3059>12-8% " XBD=2552 XHG=2511 YBD=3088 YHG=3058>of" XBD=1520 XHG=1356 YBD=3142 YHG=3103>samples " XBD=1643 XHG=1545 YBD=3133 YHG=3111>were " XBD=1803 XHG=1669 YBD=3133 YHG=3102>within " XBD=1896 XHG=1828 YBD=3134 YHG=3104>the " XBD=2071 XHG=1922 YBD=3134 YHG=3104>normal " XBD=2204 XHG=2096 YBD=3134 YHG=3103>adult " XBD=2357 XHG=2231 YBD=3142 YHG=3112>range. " XBD=2457 XHG=2410 YBD=3132 YHG=3102>In " XBD=2551 XHG=2483 YBD=3132 YHG=3101>the" XBD=1496 XHG=1328 YBD=3177 YHG=3146>second " XBD=1612 XHG=1514 YBD=3176 YHG=3146>hour " XBD=1697 XHG=1630 YBD=3176 YHG=3145>the " XBD=1941 XHG=1716 YBD=3186 YHG=3148>percentage " XBD=2036 XHG=1960 YBD=3178 YHG=3148>had " XBD=2154 XHG=2056 YBD=3177 YHG=3147>risen " XBD=2214 XHG=2172 YBD=3176 YHG=3147>to " XBD=2293 XHG=2236 YBD=3181 YHG=3147>35, " XBD=2391 XHG=2314 YBD=3176 YHG=3145>and " XBD=2464 XHG=2411 YBD=3183 YHG=3145>by " XBD=2550 XHG=2483 YBD=3175 YHG=3144>the" XBD=1460 XHG=1355 YBD=3219 YHG=3189>third " XBD=1569 XHG=1472 YBD=3219 YHG=3189>hour " XBD=1673 XHG=1584 YBD=3230 YHG=3190>75% " XBD=1736 XHG=1697 YBD=3220 YHG=3189>of " XBD=1820 XHG=1754 YBD=3221 YHG=3189>the " XBD=2000 XHG=1838 YBD=3229 YHG=3190>samples " XBD=2095 XHG=2018 YBD=3221 YHG=3189>had " XBD=2274 XHG=2113 YBD=3219 YHG=3189>reached " XBD=2402 XHG=2293 YBD=3219 YHG=3188>adult " XBD=2548 XHG=2421 YBD=3219 YHG=3188>levels." XBD=1394 XHG=1356 YBD=3262 YHG=3233>It " XBD=1459 XHG=1428 YBD=3262 YHG=3232>is " XBD=1680 XHG=1495 YBD=3262 YHG=3232>observed " XBD=1800 XHG=1713 YBD=3263 YHG=3233>that " XBD=2050 XHG=1834 YBD=3264 YHG=3234>sometimes " XBD=2149 XHG=2083 YBD=3262 YHG=3233>the " XBD=2297 XHG=2183 YBD=3270 YHG=3231>speed " XBD=2371 XHG=2331 YBD=3261 YHG=3231>of " XBD=2550 XHG=2405 YBD=3271 YHG=3231>change" XBD=1490 XHG=1355 YBD=3313 YHG=3274>taking " XBD=1624 XHG=1516 YBD=3313 YHG=3274>place " XBD=1730 XHG=1651 YBD=3307 YHG=3285>was " XBD=1852 XHG=1758 YBD=3307 YHG=3286>even " XBD=2014 XHG=1881 YBD=3307 YHG=3276>visible " XBD=2081 XHG=2042 YBD=3305 YHG=3275>in " XBD=2175 XHG=2108 YBD=3305 YHG=3275>the " XBD=2454 XHG=2203 YBD=3314 YHG=3274>increasingly " XBD=2550 XHG=2481 YBD=3305 YHG=3275>red" XBD=1484 XHG=1355 YBD=3348 YHG=3316>colour " XBD=1546 XHG=1506 YBD=3348 YHG=3318>of " XBD=1634 XHG=1567 YBD=3349 YHG=3318>the " XBD=1762 XHG=1647 YBD=3349 YHG=3319>blood " XBD=1821 XHG=1780 YBD=3350 YHG=3328>as " XBD=1868 XHG=1837 YBD=3350 YHG=3320>it " XBD=2014 XHG=1881 YBD=3349 YHG=3318>flowed " XBD=2163 XHG=2028 YBD=3356 YHG=3317>during " XBD=2199 XHG=2176 YBD=3347 YHG=3326>a " XBD=2328 XHG=2212 YBD=3357 YHG=3317>single " XBD=2543 XHG=2341 YBD=3357 YHG=3318>sampling." XBD=1414 XHG=1354 YBD=3390 YHG=3360>No " XBD=1646 XHG=1436 YBD=3392 YHG=3361>consistent " XBD=1913 XHG=1667 YBD=3400 YHG=3362>relationship " XBD=2012 XHG=1934 YBD=3391 YHG=3370>was " XBD=2153 XHG=2032 YBD=3391 YHG=3361>found " XBD=2344 XHG=2173 YBD=3391 YHG=3360>between " XBD=2432 XHG=2365 YBD=3391 YHG=3361>the " XBD=2551 XHG=2452 YBD=3391 YHG=3361>level" XBD=1392 XHG=1353 YBD=3433 YHG=3403>of " XBD=1477 XHG=1410 YBD=3434 YHG=3403>the " XBD=1586 XHG=1496 YBD=3434 YHG=3405>cord " XBD=1721 XHG=1606 YBD=3435 YHG=3405>blood " XBD=1781 XHG=1740 YBD=3435 YHG=3407>at " XBD=1904 XHG=1800 YBD=3435 YHG=3404>birth " XBD=1998 XHG=1923 YBD=3433 YHG=3403>and " XBD=2083 XHG=2016 YBD=3433 YHG=3403>the " XBD=2184 XHG=2101 YBD=3434 YHG=3405>rate " XBD=2243 XHG=2203 YBD=3433 YHG=3403>of " XBD=2405 XHG=2261 YBD=3443 YHG=3404>change " XBD=2463 XHG=2424 YBD=3434 YHG=3404>in " XBD=2550 XHG=2481 YBD=3434 YHG=3404>the

1. Amer. J. Dis. Child. 1942, 64, 843.