Plasma Membrane Fix 2

8/17/2019 Plasma Membrane Fix 2

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Plasma

MembraneCreated by :

Dyah Candra PalupiSyarifatul LailiAnggun ArifkaDiah Ajeng S.


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Function Of Plasma

Membrane• Plasma membrane is a limit betweencell and its environment.

• Plasma membrane has receptor thatbond with extracellular matrix element

• Plasma membrane also containhormone receptor

• The cell surface also containenzymatic activity


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peci!c Function Of PlasmaMembrane

". The Function Of Cell #oundary Protect the food substances in cell ome of the elements bac$!lled throu%h metabolism

ener%y

The useful substrate been collected or synthesizedby cell As place to excrete the metabolism waste

&. 'nsulatin% Function

Cells react to chan%es (evelop the receptor to reco%nize cell )ormone start to wor$ on certain receptor in plasma

membrane


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Plasma Membrane tructure(ia%ram


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urface Membrane

• The outer surface of both layer is ,surface that faced cell and facedhydrophobic

• The inner surface of both layer has Psurface that faced protoplasm andhydrophobic


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Composition PlasmaMembrane

• Plasma Membrane consist of lipidsand proteins

• There are - $inds of lipids membrane Phospholipids/ Cholesterol and0lycoprotein

• Plasma Membrane structure andchemical composition are varies


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Phospholipids/ Cholesteroland 0lycoprotein

• Phospholipids are amphipathicmolecules/ thus directly formin% alayer of micelles in a li1uid

environment.

• Cholesterol in a form of amphiphaticand located between phospholipids on

membrane.• 0lycolipids is amphiphatic membrane

element.


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Types of MembraneProteins

". Cell2cell reco%nition proteins

&. 'nte%rins

-. 'ntercellular 3unction proteins

4. ,nzymes

5. i%nal transduction proteins A$a 2 6eceptor proteins

7. Transport proteins Passive and active


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• Cell2cell reco%nition proteins 2

identify type of cell and identify a cellas 8self9 versus forei%n

– Most are %lycoproteins

• Carbohydrate chains vary between species/individuals/ and even between cell types in a%iven individual.

• 0lycolipids also play a role in cell reco%nition


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• 'nte%rins are a type of inte%ralprotein

– The cytos$eleton attaches to inte%rins

on the cytoplasmic side of themembrane

– 'nte%rins stren%then the membrane

• 'ntercellular 3unction proteins 2 helpli$e cells stic$ to%ether to formtissues


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• i%nal transduction :receptor;proteins bind hormones and othersubstances on the outside of the cell.

– #indin% tri%%ers a chan%e inside the cell.

• Called signal transduction

• ,xample The bindin% of insulin to insulin

receptors causes the cell to put %lucosetransport proteins into the membrane.


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Messenger molecule

Activatedmolecule

Receptor


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Transport of ubstances Acrossthe Plasma Membrane :PM;

". Passive Transport

› imple (i


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Passive Transport

• In passive transport substancescross the membrane by difusion

– (i


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Factors A


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imple (i


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Facilitated (i


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Facilitated (i


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Osmosis

• Osmosis @ diout of the cellthrou%h a1uaporins 2 protein y%berupa pori9 u membantu 3alannyaair melewati membran


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Osmosis Terms

Consider two solutions separated by a plasma membrane.

Hypertonic› solution with a relatively hi%h concentration of

solute

Hypotonic› solution with a relatively low concentration of

solute

Isotonic› solutions with the same solute concentration


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Osmosis and Animal Cells


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Osmosis and Plant Cells


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Active Transport

• Active transport proteins movesubstances across the PM a%ainsttheir concentration %radient.

– 6e1uires ener%y :ATP;

– Active transport proteins are hi%hlyselective

– Active transport is needed for properfunctionin% of nerves and muscles


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Active Transport

ATP

ATP

P

ADP


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Vesicle

Fluid outside cell

Protein

ytoplasm

ExocytosisExocytosis


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E d t iE d t i


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Vesicle #orming

EndocytosisEndocytosis

,ndocytosis can occur in three ways,ndocytosis can occur in three ways

Pha%ocytosis :Dcell eatin%D;Pha%ocytosis :Dcell eatin%D;

Pinocytosis :Dcell drin$in%D;Pinocytosis :Dcell drin$in%D;


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,ndocytosis

• ,ndocytosis

– PM sin$s inward/ pinches o< and forms avesicle

– Besicle often mer%es with 0ol%i forprocessin% and sortin% of its contents


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,ndocytosis 2 terms

• Pha%ocytosis @ cell eatin%

– Membrane sin$s in and captures solidparticles for transport into the cell

– ,xamples

• olid particles often include bacteria/cell debris/ or food

• Pinocytosis @ cell drin$in% – Cell brin%s in a li1uid

http://academic.brooklyn.cuny.edu/biology/bio4fv/page/phago.htmhttp://academic.brooklyn.cuny.edu/biology/bio4fv/page/phago.htm


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T)A=G FO6

HOI6

ATTA=T'O=


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". Protein apa yan% masu$ pada prosesendositosis J Kida rL

&. Pada slide $e & pada proses e$sositosis

apa$ah ada fa$tor protein tertentu yan%mendoron% pen%eluaran tersebut J :nira;

-. Apa fun%si reseptor ion/ reseptor tirosin $inasedan protein 0 J :ridlo;

4. Apa$ah fun%si membran plasma selalu tetap /

$alau bisa rusa$/ $enapa J :nayla;5. Apa$ah stru$tur membran sama $eti$a

mela$u$an endositosis dan e$sositosis sepertidi$etahui terdapat sitos$eleton J :adini;

7. Fa$tor apa yan% menyebab$an salahpenerimaan sinyal di reseptor J :nina;

N. i$a plasma membran sudah rusa$ apa$ah adasistem pertahanan di dalam sel J :noya;

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Plasma Membrane Fix 2