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Porcine Xenograft PowerPoint presentation
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Porcine Heterografts
Types of Grafts
Heterografts: tissues transferred from one species to an unrelated species (xenografts / zoografts)
Homografts: tissues transferred from one individual to another of the same species
Autografts: tissue trasnferred from one area to another of the same individual
What is a Porcine Graft?
Xenograft From domestic pig sacrificed at 6
months of age Split-thickness skin – 0.01 inches Preparation types:
Antibiotic & bleach soak then electron beam
Saturated with antiseptic solution or aldehyde starches
Biological Advantages
Augment host immune defence & decreased bacterial count
Re-establishes vapor barrierDecreased water & protein loss
Increased rate of epithelialization No apparent immune response
Clinical Advantages
Alleviates pain Protects cartilage, tendons, bone,
nerves Facilitates motion and mobility Avoidance of harvesting STSG Inexpensive and unlimited supply
Indications
Large wounds Areas difficult to close Partial closure and granulation
before delayed repair (avascular areas)
Flap or graft contraindicated
Contraindications
Known sensitivity to porcine products
History of multiple or serum allergies
Wounds with large amounts of eschar
Types of Porcine Grafts
PerforatedPromotes drainage
Non-perforatedCartilage or bone areasMinimizes air exposure and
deceases pain
Porcine Xenograft
E•Z Derm™Nonperforated
Porcine Biosynthetic Wound Dressing
Porcine Heterografts in Dermatologic Surgery and Reconstruction
Davis, DA and Arpey, CJDermatol Surg 2000;26:76–80
The End