Local Partner Organisations

Over the years we have established close working relation-

ships and are using synergistic effects with the following

partners

Trium Analysis Online GmbH

State-of-the-art IT solutions: eTrials, Data

Warehousing, Telemonitoring

Ludwig Maximilians University Munich

Contractual Academic Partner for Research

in Statistics, Biostatistics and Medicine

Technical University of Munich

Joint Academic Research in Medicine,

Mathematics and Informatics

Marianne Strauß Clinic MS Treatment Center

Clinical curricula for center staff and piloting

of research ideas with Germanys largest

MS clinic (1,800 pts/year)

The Sylvia Lawry Centre is a

German based non-for-profit

organisation. It was estab-

lished in February 2001 to

support research into the

causes of multiple sclerosis

and to accelerate the deve-

lopment of effective thera-

pies, by using innovative sta-

tistical methods and state-

of-the art computer techno-

logy combined with medical

expertise.

The Centre has been

supported by data donors –

pharmaceutical companies

and individual clinical

investigators – who have

already contributed 50

datasets from essentially

all clinical trials and natural

history studies that have

been done in MS over the

past 20 years.

The Centre is directed by

Dr. Martin Daumer.

INDEPENDENT

RESEARCH AND

I SERVICE N

CLINICAL

TRIALS

Imprint

Sylvia Lawry Centre for Multiple Sclerosis Research e.V.

Hohenlindener Str.1

D-81677 München

phone: +49 89 2060 269 50

fax: +49 89 2060 269 51

info@slcmsr.org

www.slcmsr.org

Sylvia Lawry

Local Partner OrganisationsOver the years we have established close working relationships and are using synergistic effects with the following partners

Trium Analysis Online GmbH State-of-the-art IT solutions: eTrials, Data Warehousing, Telemonitoring Ludwig Maximilians University Munich Contractual Academic Partner for Research in Statistics, Biostatistics and Medicine Technical University of Munich Joint Academic Research in Medicine, Mathematics and Informatics Marianne Strauß Clinic MS Treatment Center Clinical curricula for center staff and piloting of research ideas with Germanys largest MS clinic (1,800 pts/year)

The Sylvia Lawry Centre is a German based non-for-profit organisation. It was estab-lished in February 2001 to support research into the causes of multiple sclerosis and to accelerate the deve- lopment of effective thera-pies, by using innovative sta-tistical methods and state-of-the art computer techno- logy combined with medical expertise.

The Centre has beensupported by data donors – pharmaceutical companies and individual clinical investigators – who have already contributed 50 datasets from essentially all clinical trials and natural history studies that have been done in MS over the past 20 years. The Centre is directed by Dr. Martin Daumer.

INDEPENDENT RESEARCH ANDSERVICE IN CLINICAL TRIALS

The Sylvia Lawry Centre

ImprintSylvia Lawry Centre for Multiple Sclerosis e.V.Hohenlindener Str.1D-81677 München

phone: +49 89 2060 269 50fax: +49 89 2060 269 51info@slcmsr.orgwww.slcmsr.org

Clinical Trial Requirements

Trial Design

Sample Size Calculation

Statistical Analysis Plan

Statistical Programming

DSMB Participation

Data Management

Statistical Analysis & Report

Scientific Advice

Support in Regulatory Affairs

Project Management (with subcontractors)

International Monitoring (with subcontractors)

Electronic Data Capture (with Trium)

Electronic Management Tools (with Trium)

Beyond Clinical Trials

Webbased Online Analytical Processing Risk Assessment Tools Online Decision Support Database and Registry Design and Hosting Data Pooling and Warehousing Telemonitoring Collaborative Workspace Systems (Intranets/Portals)

Business Plan/Centre financing

The Centre’s operations are financed from a mixture of sources and the application of funds is overseen and controlled by a supervisory body Contract Research Joint Grant Proposals Unrestricted Grants Governmental Support Earmarked Donations