1
Nutritional assessment S85 107 of the 815 cases (13.1%) the diagnosis of malnutrition triggered additional revenues of 1,387€ per case, in total amounting to 148,465€. The cost of nutritional therapy was preliminarily estimated to be about 80€ per case. Number of cases with malnutrition diagnosed and coded Severe Moderate Mild Total 2012 (baseline) 21 168 10 199 2013 201 548 66 815 Conclusion: The 1-year evaluation of this project shows that targeted screening for malnutrition boosts the rate of detection and the patients may then be offered suitable nutritional support. Our data also suggest that nutrition therapy is a cost-effective measure to fight disease-related malnutrition. Disclosure of Interest: None Declared. PP174-SUN VALIDATION OF MULTIPLE 24-HOUR RECALLS IN DUTCH ELITE ATHLETES BY MULTIPLE 24-HOUR URINARY NITROGEN EXCRETIONS F. Wardenaar 1 , J. Steenis 2 , M. Mensink 3 , J. de Vries 3 . 1 Sports and Exercise Studies, HAN University of Applied Sciences, Nijmegen, 2 InnoSportLab Papendal, Arnhem, 3 Human Nutrition, Wagening University, Wageningen, Netherlands Rationale: Multiple dietary recalls are considered a good tool to estimate dietary intake. In the present study we aimed to validate the protein intake by multiple 24 hour recalls (24HR) with multiple 24 hour nitrogen in urine (24HN) in elite athletes. Methods: Forty-eight healthy disabled and non-disabled Dutch male and female elite athletes (aged 18 50 y) participated in the study. Subjects reported dietary intake on 3 independent days by a web-based 24HR, and collected 3 time 24HN during 3 week period, at least 3 days apart. Completeness of urine collection was checked with using PABA supplements. To examine whether nitrogen-balance was stable, body weight was measured on recall days and creatinine levels were analysed in the 24HN. Urine samples were analyzed on nitrogen content with the Kjeldahl-method. Repeated Measured ANOVA (using Mixed Models) was performed to examine changes in creatinine and body weight over the research period. Correlation analysis was performed to assess the association between reported protein intake from 24hR and protein calculated from 24HN levels. Results: Mean±SD protein intake estimated by the 24 h recall was 107±36 g/d and by the 24 h urine was 142±39 g/d. Thus, the 24 h recall method underestimated the mean actual protein intake with 35.5±32 g/d or 30%. Urinary creatinine levels and body weight did not differ between the recall days (p = 0.08 and p = 0.78, respectively). Crude correlation between the intake estimates was r = 0.61 (95% CI: 0.42 0.74), and after correction for energy intake and body weight it was r = 0.54 (95% CI: 0.33 0.70). Conclusion: Based on the stable bodyweight and urinary creatinine levels the assumption of nitrogen-balance appears to be correct. Therefore, the amount of urinary nitrogen most likely best reflects protein intake. We conclude that multiple 24HR underestimate protein intake in elite athletes with approximately one-third. Disclosure of Interest: None Declared. PP175-SUN EFFECT OF NUTRITIONAL STATUS ON FUNCTIONALITY: SCOUTING BODY COMPOSITION CONFOUNDING VARIABLES IN ELDERLY S. Perna 1 , S. Sacco 1 , G. Peroni 1 , M.A. Faliva 1 , D. Guido 1 , M. Rondanelli 1 . 1 University of Pavia, Pavia, Italy Rationale: The aim of the present study was to assess the potential confounding role of body fat distribution markers, measured by DEXA device, on the causal relationship between MNA levels and Barthel Index. Methods: A study was conducted on 164 elderly (65+ y) patients (120 females, 44 males, age = 82±6.62 y). Barthel Index (58.52±26.90 u), MNA levels (17.89±4.04 u) and body fat distribution markers, i.e. fat mass (19.898±8.889 kg), fat mass% (31.80±11.10), android% (34.63±12.20) and ginoid% (38.58±10.25), were measured. We used a multiple linear regression models adjusted for gender, age and BMI. We verified the crude relationship between MNA levels and Barthel Index and verified which body fat distribution markers were associated to the MNA levels and which of them could be classified as potential confounders. Finally, they assessed the confounding effect (D%) for each body fat distribution marker and also fitted the overall regression model. Results: The crude effect of MNA levels on Barthel Index resulted equal to +1.8843 (P < 0.001). According to gender, age and BMI, for a unit increase of MNA level, functionality increased of 1.8843 Barthel units: this effect was very strong. All fat distribution markers showed a positive and highly significant association (P < 0.001) with nutritional index. Finally, according to the last regression models adjusted for potential confounders, the percentage variations of MNA- Barthel causal effect resulted +3.2% for fat mass, +6.9% for fat mass%, +1.2% for android% and +4.5% for ginoid%. Conclusion: Results shows that the magnitude of MNA-Barthel causal relationship could be reduced by the presence of an excess of fat mass also in normal weight elderly subjects. Fat mass could mask the presence of a condition of hypercaloric malnutrition not revealed by MNA. Disclosure of Interest: None Declared. PP176-SUN RESTING ENERGY EXPENDITURE IN PATIENTS WITH MYOTONIC DYSTROPHY IN RELATION TO BODY COMPOSITION P.L.M. Reijven 1 . 1 Dietetics, University hospital Maastricht, Maastricht, Netherlands Rationale: Myotonic dystrophy (MD) is an inheritable multisys- tem disorder characterized by muscle weakness and multiple organ impairment. Patients are prone to develop malnutrition. True caloric needs are often not known. Aim: To compare measured resting energy expenditure (REE) in patients with MD with predicted values. Methods: In 61 patients (28 female, 33 male) REE was mea- sured by indirect calorimetry (ventilated hood system) and compared with Harris Benedict predictions. Body composition was measured with the skinfold technique.

PP174-SUN: Validation of Multiple 24-hour Recalls in Dutch Elite Athletes by Multiple 24-hour Urinary Nitrogen Excretions

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Page 1: PP174-SUN: Validation of Multiple 24-hour Recalls in Dutch Elite Athletes by Multiple 24-hour Urinary Nitrogen Excretions

Nutritional assessment S85

107 of the 815 cases (13.1%) the diagnosis of malnutritiontriggered additional revenues of 1,387€ per case, in totalamounting to 148,465€. The cost of nutritional therapy waspreliminarily estimated to be about 80€ per case.

Number of cases with malnutrition diagnosed and coded

Severe Moderate Mild Total

2012 (baseline) 21 168 10 1992013 201 548 66 815

Conclusion: The 1-year evaluation of this project showsthat targeted screening for malnutrition boosts the rate ofdetection and the patients may then be offered suitablenutritional support. Our data also suggest that nutritiontherapy is a cost-effective measure to fight disease-relatedmalnutrition.

Disclosure of Interest: None Declared.

PP174-SUNVALIDATION OF MULTIPLE 24-HOUR RECALLS IN DUTCHELITE ATHLETES BY MULTIPLE 24-HOUR URINARY NITROGENEXCRETIONSF. Wardenaar1, J. Steenis2, M. Mensink3, J. de Vries3. 1Sportsand Exercise Studies, HAN University of Applied Sciences,Nijmegen, 2InnoSportLab Papendal, Arnhem, 3HumanNutrition, Wagening University, Wageningen, Netherlands

Rationale: Multiple dietary recalls are considered a good toolto estimate dietary intake. In the present study we aimedto validate the protein intake by multiple 24 hour recalls(24HR) with multiple 24 hour nitrogen in urine (24HN) in eliteathletes.Methods: Forty-eight healthy disabled and non-disabled Dutchmale and female elite athletes (aged 18 50 y) participated inthe study. Subjects reported dietary intake on 3 independentdays by a web-based 24HR, and collected 3 time 24HNduring 3 week period, at least 3 days apart. Completeness ofurine collection was checked with using PABA supplements.To examine whether nitrogen-balance was stable, bodyweight was measured on recall days and creatinine levelswere analysed in the 24HN. Urine samples were analyzedon nitrogen content with the Kjeldahl-method. RepeatedMeasured ANOVA (using Mixed Models) was performed toexamine changes in creatinine and body weight over theresearch period. Correlation analysis was performed to assessthe association between reported protein intake from 24hRand protein calculated from 24HN levels.Results: Mean±SD protein intake estimated by the 24 h recallwas 107±36 g/d and by the 24 h urine was 142±39 g/d. Thus,the 24 h recall method underestimated the mean actualprotein intake with 35.5±32 g/d or 30%. Urinary creatininelevels and body weight did not differ between the recalldays (p = 0.08 and p = 0.78, respectively). Crude correlationbetween the intake estimates was r = 0.61 (95% CI: 0.42 0.74),and after correction for energy intake and body weight it wasr = 0.54 (95% CI: 0.33 0.70).Conclusion: Based on the stable bodyweight and urinarycreatinine levels the assumption of nitrogen-balance appearsto be correct. Therefore, the amount of urinary nitrogenmost likely best reflects protein intake. We conclude that

multiple 24HR underestimate protein intake in elite athleteswith approximately one-third.

Disclosure of Interest: None Declared.

PP175-SUNEFFECT OF NUTRITIONAL STATUS ON FUNCTIONALITY:SCOUTING BODY COMPOSITION CONFOUNDING VARIABLESIN ELDERLYS. Perna1, S. Sacco1, G. Peroni1, M.A. Faliva1, D. Guido1,M. Rondanelli1. 1University of Pavia, Pavia, Italy

Rationale: The aim of the present study was to assess thepotential confounding role of body fat distribution markers,measured by DEXA device, on the causal relationship betweenMNA levels and Barthel Index.Methods: A study was conducted on 164 elderly (65+ y)patients (120 females, 44 males, age = 82±6.62 y). BarthelIndex (58.52±26.90 u), MNA levels (17.89±4.04 u) and bodyfat distribution markers, i.e. fat mass (19.898±8.889 kg), fatmass% (31.80±11.10), android% (34.63±12.20) and ginoid%(38.58±10.25), were measured. We used a multiple linearregression models adjusted for gender, age and BMI. Weverified the crude relationship between MNA levels and BarthelIndex and verified which body fat distribution markers wereassociated to the MNA levels and which of them could beclassified as potential confounders. Finally, they assessed theconfounding effect (D%) for each body fat distribution markerand also fitted the overall regression model.Results: The crude effect of MNA levels on Barthel Indexresulted equal to +1.8843 (P< 0.001). According to gender,age and BMI, for a unit increase of MNA level, functionalityincreased of 1.8843 Barthel units: this effect was verystrong. All fat distribution markers showed a positive andhighly significant association (P< 0.001) with nutritional index.Finally, according to the last regression models adjusted forpotential confounders, the percentage variations of MNA-Barthel causal effect resulted +3.2% for fat mass, +6.9% forfat mass%, +1.2% for android% and +4.5% for ginoid%.Conclusion: Results shows that the magnitude of MNA-Barthelcausal relationship could be reduced by the presence of anexcess of fat mass also in normal weight elderly subjects. Fatmass could mask the presence of a condition of hypercaloricmalnutrition not revealed by MNA.

Disclosure of Interest: None Declared.

PP176-SUNRESTING ENERGY EXPENDITURE IN PATIENTS WITHMYOTONIC DYSTROPHY IN RELATION TO BODY COMPOSITIONP.L.M. Reijven1. 1Dietetics, University hospital Maastricht,Maastricht, Netherlands

Rationale: Myotonic dystrophy (MD) is an inheritable multisys-tem disorder characterized by muscle weakness and multipleorgan impairment. Patients are prone to develop malnutrition.True caloric needs are often not known.Aim: To compare measured resting energy expenditure (REE)in patients with MD with predicted values.Methods: In 61 patients (28 female, 33 male) REE was mea-sured by indirect calorimetry (ventilated hood system) andcompared with Harris Benedict predictions. Body compositionwas measured with the skinfold technique.