PQCNC SIVB LS3 Labor Induction in Nulliparous Patients

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    Labor Induction in

    Nulliparous Patients

    PQCNC Spring Meeting

    April 9, 2013

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    Arthur Ollendorff, MDMedical Director

    MAHEC OB/GYN Specialists

    Asheville, NC

    Clinical Professor of OB/GYN

    University of North Carolina SOM

    [email protected]

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    Objectives

    Summarize the statistics andevidence behind induction of labor

    (IOL) Review the Community Care of North

    Carolina (CCNC) Pregnancy Medical

    Home pathway for induction of

    nulliparous patients

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    Induction of Labor

    Rates have been increasing over thepast 20 years

    Reasons are unclear but may includelPatient/Provider preferencel Increasing medical complications

    among pregnant womenlAccess to care in certain areas

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    0

    5

    10

    15

    20

    25

    30

    35

    1990 2000 2005 2008

    IOL

    C/S

    US Births: Rates of Cesarean

    Delivery and Induction of Labor

    U.S. National Center for Health Statistics

    Percent

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    U.S. Induction Rate Change by

    Gestational Age (1990-2005)

    National Vital Statistics Reports; Vol 56, no 6.

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    NC Births: Rates of Cesarean Delivery and

    Induction of Labor (2007-2011)

    0

    5

    10

    15

    20

    25

    30

    35

    2007 2008 2009 2011

    IOL

    C/S

    The Baby Book. NC State Center for Health Statistics

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    IOL Is Not a Bad Thing

    Critical to distinguish elective frommedically indicated induction

    lPatient counselinglPatient safetylData collection

    Elective IOL is necessary at times butshould be used judiciously

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    Obstetrics is a Balance

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    In order to review any IOL

    pathway

    1. What are the medical indications forIOL?

    2. What are the risks of IOL?3. What is a failed induction?4. How can we choose the patients

    most likely to have a successful IOL?

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    Medical Indications for IOL

    There is some consensus and far lessdata to support the best practice for

    induction of labor in certain clinicalsituations

    There are some guidelines that existbased primarily on expert opinion

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    Medical Indications for IOL

    Abruptio placentae Chorioamnionitis Fetal demise Gestational hypertension Preeclampsia, eclampsia Premature rupture of membranes Post-term pregnancy Maternal medical conditions (eg, diabetes mellitus, renal

    disease, chronic pulmonary disease, chronichypertension, antiphospholipid syndrome)

    Fetal compromise (severe fetal growth restriction,isoimmunization, oligohydramnios)

    Induction of Labor. ACOG Practice Bulletin No. 107. August 2009.

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    Non-medical Indications for

    IOL

    Labor also may be induced logisticreasons

    lrisk of rapid laborldistance from hospitallpsychosocial indications.

    Induction of Labor. ACOG Practice Bulletin No. 107. August 2009.

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    Indications and Timing for

    Late Preterm Delivery

    Spong et alObstetrics & Gynecology (2011) 118(2)

    Condition GA

    Chronic Hypertension 36-39 weeks

    Mild Pre-eclampsia 37 weeks

    Diabetes, well-controlled EIOL not advised

    Diabetes, poorly controlled 34-39 weeks

    Fetal congenital malformations 34-39 weeks

    Oligohydramnios, isolated and persistent 36-37 weeks

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    Latest ACOG Opinion (April 2013)

    Non-medically Indicated Early-Term Deliveries. ACOGCommittee Opinion 561. April 2013

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    What are the risks of IOL?

    Cesarean delivery Prolonged labor Increased risk of chorioamnionitis Postpartum hemorrhage Tachysystole Neonatal morbidity

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    Nullipara Rate of Cesarean Section:

    Spontaneous vs. Induced Labor

    0

    2

    4

    6

    8

    10

    12

    14

    16

    18

    20

    Seyb Maslow Cammu Dublin

    EIOL

    Spontanous Labor

    Frequen

    cyofCesarean

    Delivery(%)

    Adapted from WA Grobman. Semin Perinatol 36:344-347

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    What is a Failed Induction?

    A. Not able to get patient into activelabor

    B. Not achieving a vaginal deliveryC. Both

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    Failed Induction

    Defined as not able to achieve activelabor during the course of induction

    A latent phase of as long as 18 hoursduring induction of labor in nulliparous

    women allows the majority of these

    women to achieve a vaginal delivery

    Simon et al. Obstet Gynecol 2005; 105:7059

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    Defining Arrest of Labor

    Conventional Wisdom

    4 cm defines active laborArrest of dilation after 2

    hours of adequatecontractions in activephase

    Second stage should lastno more than 3 hours

    Newer Data Suggests

    6 cm defines active labor Arrest of dilation after 4

    hours of adequatecontractions in activephase

    Second stage may last upto 4 hours

    El-Sayed YY. Diagnosis and Management of Arrest Disorders:Duration to Wait. Semin Perinatol 2012; 36:374-378.

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    Practical Considerations

    Indication for InductionlProvider may rightfully be less patient

    in a patient with severe pre-eclampsiathan for another indication

    Method of InductionlFoley bulb will get a patient to 4-5 cm

    fairly quickly but are they actually in

    labor?

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    Can We Predict Successful

    IOL Candidates?

    Patients with an unfavorable cervixhave a higher chance of Cesarean

    delivery than those with a favorablecervix

    Cervical ripening does not lower therisk of Cesarean delivery

    lDecreases failed inductionlShortens time from induction to

    delivery

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    Bishop Score

    Score of < 6 isunfavorable

    Score of

    8confers same

    likelihood of

    vaginal delivery

    as spontaneouslabor

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    Why Did CCNC PMH Develop

    an Induction Guideline?

    Judicious use of induction can helpmeet two of PMH goals

    lReduction in Cesarean SectionlEliminate elective IOL prior to 39

    weeks

    It dovetails well with several othernational initiatives

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    CherokeeGraham

    Swain

    Clay MaconJackson

    Haywood

    Madison

    Buncombe

    Henderson

    McDowellRutherford

    Polk

    Burke

    Cleveland

    Watauga

    CaldwellAlexander

    CatawbaLincolnGaston

    Ashe

    Wilkes

    AlleghanySurry

    Yadkin

    Iredell

    Mecklenburg

    Union

    StanlyCabarrus

    Rowan

    Davie

    Stokes

    Forsyth

    Davidson

    Anson

    Rockingham

    Guilford

    Randolph

    Montgomery

    Richmond

    Caswell

    Chatham

    Orange

    Person

    LeeMoore

    HokeScotland

    Robeson

    Cumberland

    Harnett

    Wake

    Va

    nce

    Franklin

    Warren

    Johnston

    Sampson

    Bladen

    ColumbusBrunswick

    Pender

    Duplin

    Wayne

    Wilson

    Nash

    HalifaxNorthhampton

    Edgecombe

    PittGreeneLenoir

    Jones

    Onslow Carteret

    CravenPamlico

    BeaufortHyde

    Martin

    Bertie

    HertfordGates

    WashingtonTyrrellDare

    Alamance DurhamGranville

    Ne

    wHanover

    Chowan

    ar

    Source:CCNCMarch2013

    Legend

    AccessCareNetworkSites CommunityCarePlanofEasternCarolina

    AccessCareNetworkCoun?es CommunityHealthPartners

    CommunityCareofWesternNorthCarolina NorthernPiedmontCommunityCare

    CommunityCareoftheLowerCapeFear NorthwestCommunityCare

    CarolinaCollabora?veCommunityCare PartnershipforCommunityCare

    CommunityCareofWakeandJohnstonCoun?es CommunityCareoftheSandhills

    CommunityCarePartnersofGreaterMecklenburg CommunityCareofSouthernPiedmont

    CarolinaCommunityHealthPartnership

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    CCNC Pregnancy Medical

    Home Program

    An outcome-driven initiative monitoredfor specific performance standards

    lParticipating practices receivefinancial incentives and support fromthe local CCNC network

    lPractices agree to work toward qualityimprovement goals

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    Pregnancy Medical Home

    Program Quality Goals

    Reducing elective deliveries prior to 39weeks

    Performing standardized initial riskscreening

    l Collaborating with pregnancy caremanagement programs to serve high-risk

    patients

    Using 17P to prevent recurrent preterm birth Reducing primary Cesarean Section rate

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    NC Pregnancy Medical

    Pathways

    Collaborative effort of the PregnancyMedical Home Physician Champions

    l to promote evidence-based, bestpractice care statewide

    Three pathways currently existlHypertensive Diseases in PregnancylScreening for Preterm Deliveryl Induction of Labor-Nullipara

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    Choosing Wisely

    An initiative by ABIM Foundation tohelp physicians and patients engage

    in conversations to reduce overuse oftests and procedures

    ACOG is a partner in this initiativel Identified Five Things Physicians and

    Patients Should Question

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    Disclaimer

    Pregnancy Medical Home Care Pathways are intended to assistproviders of obstetrical care in the clinical management of

    problems that can occur during pregnancy. They are intended tosupport the safest maternal and fetal outcomes for patients

    receiving care at North Carolina Pregnancy Medical Homepractices. This pathway was developed after reviewing the Society

    for Maternal-Fetal Medicine and the American College of

    Obstetricians and Gynecologists resources such as practicebulletins, committee opinions, and Guidelines for Perinatal Care as

    well as current obstetrical literature. PMH Care Pathways offer a

    framework for the provision of obstetrical care, rather than aninflexible set of mandates. Clinicians should use their professional

    knowledge and judgment when applying pathwayrecommendations to their management of individual patients.

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    Highlights of the CCNC

    Induction Pathway

    Intended for nulliparous patients only Do not induce labor before 39 weeks

    unless there is a medical indication Do not electively induce labor with an

    unfavorable cervix before 41 weeks

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    First Decision Point

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    Second Decision Point

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    Medical Indication Side

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    Elective Indication Side

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    ACOG Patient Safety

    Checklist No. 5

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    References used for CCNC IOL

    Pathway

    1. Induction of Labor. ACOG Practice Bulletin No. 107, August 20092. Fetal Lung Maturity. ACOG Practice Bulletin No. 97, September 2008.3. Spong CY, Mercer BM, DAlton M, et al. Timing of indicated late-

    preterm and early-term birth. Obstet Gynecol 2011;118:323-33.

    4.ACOG/ACP Guidelines for Perinatal Care, Sixth edition. WashingtonDC, November 2007.

    5. Scheduling induction of labor. Patient Safety Checklist No. 5. AmericanCollege of Obstetricians and Gynecologists. Obstet Gynecol

    2011;118:14734.

    6. Grobman WA. Predictors of Induction Success, Semin Perinatol 2012;36:344-347

    7. Swamy GK. Current Methods of Labor Induction. Semin Perinatol 2012;36:348-352.

    8. El-Sayed YY. Diagnosis and Management of Arrest Disorders: Durationto Wait. Semin Perinatol 2012; 36:374-378.