Product List - CAD Pharmacadpharma.com/pdf/intermediates.pdf · 2016. 1. 4. · 2- (5 -Bromo-2-methylbenzyl)-5- (4 -fluorophenyl)thiophene 1030825- 20 -7 5-Bromo-2-chlorobenzoic acid

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Product List

Intermediates CAS No.

Abiraterone intermediates

-hydroxy-androst-5-ene-17-hydrazone 63015-10-1

17-Iodoandrosta-5,16-dien-3beta-ol 32138-69-5

diethyl-(pyridin-3-yl)-borane 89878-14-8

-hydroxy-17-iodo-androsta-5,16-diene 32138-69-5

Acitretin Intermediates

4-Methoxy-2,3,6-trimethyl-benzaldehyde 54344-92-2

(3E)-4-(4-methoxy-2,3,6-trimethylphenyl)but-3-en-2-one 62924-31-6

Acotiamide Intermediates

N-(2-(Diisopropylamino)ethyl)-2-((2-hydroxy-4,5-dimethoxybenzoyl)amino)-

1,3-thiazole-4-carboxyamide

185106-16-5

2-Hydroxy-4,5-dimethoxybenzoic acid 5722-93-0

2-Aminothiazole-4-carboxylic acid 40283-41-8

N1,N1-diisopropylethane-1,2-diamine 14165-22-1

N-Ethyl-N-isopropylpropan-2-amine 7087-68-5

Adefovir Dipivoxil Intermediates

PMEA 106941-25-7

Afatinib Intermediates

4-Quinazolinamine,N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro 162012-67-1

Acetic acid,2-(diethoxyphosphinyl) 3095-95-2

Ethanamine,2,2-diethoxy-N,N-dimethyl 3616-56-6

Agomelatine

7-Methoxy-1-naphthylacetonitrile 138113-08-3

mailto:[email protected]

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7-Methoxy-1-Tetralone 6836-19-7

Alogliptin Intermediates

(R)-3-Boc-aminopiperidine 309956-78-3

2- [(6-C hloro-3,4-dihydro-3-m ethyl-2,4-dioxo-1(2H)-

pyrimidinypmethyllbenzonitrile

865758-96-9

(R)-3-Piperidinamine dihydrochloride 334618-23-4

6-Chloro-3-methyluracil 4318-56-3

2-Cyanobenzyl bromide 22115-41-9

Alosetron Hydrochloride Intermediates

2,3,4,5-Tetrahydro-5-methyl-1H-pyrido[4,3-b]indol-1-one 122852-75-9

Almotriptan Intermediates

4-chlorobutyraldehyde diethy acetal 6139-83-9

1-((4-Aminobenzenemethane)sulfonyl)pyrrolidine 334981-10-1

4-(1-Pyrrolidinylsulforylmenthyl)phenylhydrazine hydrochloride 334981-11-2

Allopurinol Intermediate

3-Amino-Pyrazole-4-Carboxamide Hemisulfate 27511-79-1

Ambrisentan Intermediates

4,6-Dimethyl-2-methylsulfonylpyrimidine 35144-22-0

Amprenavir Intermediates

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-

Phenylbutane

98737-29-2

(3S)-3-(tert-Butoxycarbonyl)amino-1-

chloro-4-phenyl-2-butanone

102123-74-0

(1S,2S)-(1-Benzyl-3-chloro-2-

hydroxypropyl)carbamic acid tert-butyl

ester

165727-45-7

Anagliptin


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2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid 739364-95-5

2-Methyl-1,2-propanediamine 811-93-8

Apixaban Intermediates

Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate 27143-07-3

5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-

pyridinone

545445-44-1

1-(4-Methoxypheny1)-7-oxo-6-[4-(2-oxopiperid in-l-yOphenyl]-4,5,6,7-

tetrahydro-11-1-pyrazolo[3,4-c]pyridine-3-carboxylie acid ethyl ester

503614-91-3

Arobicin Intermediates

2-Amino-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenecarboxylic acid 99907-84-3

Amrubicin 110267-81-7

Atazanavir Intermediates

(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-

epoxy-4- phenylbutane

98760-08-8

Moc-L-tert-Leucine 162537-11-3

L-tert-Leucine 20859-02-3

2-[[4-(2-Pyridinyl)phenyl]methyl]-

hydrazinecarboxylic acid 1,1-dimethylethyl

ester

198904-85-7

2-[[4-(2-Pyridinyl) phenyl] methyl]-

hydrazinecarboxylic acid 1, 1-dimethylethyl

ester

127406-56-8

Atorvastatin Calcium Intermediates

Ats-4 86728-85-0

Ats-5 141942-85-0

Ats-8 125971-94-0


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Ats-9 125995-13-3

M-3 125971-57-5

M-4 125971-96-2

Axitinib Intermediates

(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-

indazole

886230-77-9

(E)-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-

amine

886230-76-8

2-mercapto-N-methylbenzamide 20054-45-9

Azelnidipine Intermediates

2-(3-nitrobenzylidene)acetoacetate Isopropyl 39562-25-9

1-Diphenylmethyl-3-hydroxyazetidine 1862-17-5

1-benzhydrylazetidine-3-carbonitrile 36476-86-5

3-amino-3-iminopropanoic acid 1-(diphenylmethyl)-3-azetidinyl ester acetate 170749-59-4

Azilsartan Intermediates

1H-BenziMidazole-7-carboxylic acid, 1-[[2'-(2,5-dihydro-5-oxo-1,2,4-oxadiazol-

3-yl)[1,1'-biphenyl]-4-yl]Methyl] -2-ethoxy-, Methyl ester

147403-52-9

Bataxolol Intermediates

(Bromomethyl)cyclopropane 7051-34-5

Biapenem Intermediates

6,7-Dihydro-6-mercapto-5H-pyrazolo[1,2-a][1,2,4]triazolium chloride 153851-71-9

Bortezomib Intermediates

(aR)-(1S,2S,3R,5S)-Pinanedio1-1-amino-3-methylbutane-l-boronate

Trifluoroacetate

179324-87-9

Bortezomibpinanediol ester 205393-22-2

Bosutinib Intermediates

4-Chloro-3-cyano-7-hydroxy-6-methoxyquinoline 263149-10-6


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4-Chloro-7-fluoro-6-methoxy-3-quinolinecarbonitrile 622369-40-8

4-Chloro-7-(3-chloropropoxy)-3-cyano-6-methoxyquinoline 214470-68-5

3-Quinolinecarbonitrile,4-chloro-6-Methoxy-743-(4-Methyl-l-

piperazinyl)propoxy]

492444-39-0

Brinzolamide Internediates

3-Acetyl-2,5-dichlorothiophene 36157-40-1

3-(Bromoacetyl)-5-chloro-2-thiophenesulfonamide 160982-11-6

(S)-3,4-Dihydro-6-chloro-4-hydroxy-2H-thieno[3,2-e]-1,2-thiazine-1,1-dioxide 160982-16-1

(S)-3,4-Dihydro-4-hydroxy-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-

thiazine-6-sulfonamide 1,1-dioxide

154127-42-1

Candesartan Cilexetil Intermediates

Ethyl-2-t-butoxy-2-carboxylamino-3-nitrobenzoate 136285-65-9

Ethyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl)methyl] benzimidazole-7-

carboxylate

139481-41-7

Methyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl)methyl] benzimidazole-7-

carboxylate

139481-44-0

Ethyl-2-ethoxy-1-[[(2'-(1Htetrazol-5-yl)biphenyl-4-yl-)methyl]benzimidazole-

7-carboxylate

139481-58-6

2-ethoxy-1-[[(2'-(1Htetrazol-5-yl)biphenyl-4-yl-)methyl] benzimidazole-7-

carboxylic acid

139481-59-7

Trityl Candesartan 139481-72-4

Trityl Candesartan Cilexetil 170791-09-0

Cyclohexyl-(1-chloroethyl)-carbonate 99464-83-2

Canagliflozin Intermediates

2-(4-Fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 898566-17-1


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2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene 1030825-20-7

5-Bromo-2-chlorobenzoic acid 79669-49-1

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone 32384-65-9

2-(4-Fluorophenyl)thiophene 58861-48-6

(5-bromo-2-methylphenyl)[5-(4-fluorophenyl)-2-thienyl]- Methanone 1132832-75-7

Capecitabine Intermediates

1，2，3-triacetyl-5-deoxy- -D-Riboturanose 62211-93-2

2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine 161599-46-8

Carfilzomib Intermediates

Morpholin-4-ylacetic acid 3235-69-6

(alphaS)-alpha-Am inobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester

mono (trifluoroacetate)

868539-99-5

[(1S)-3-Methy1-1-[[(2R)-2-methyloxiranyl]carbonylibutyl]carbamicacid 1,1-

dim ethylethyl ester

247068-82-2

(2S)-2-Amino-4-methy1-1-[(2R)-2-methyloxirany1]-1-pentanone

trifluoroacetate

247068-85-5

875309-83-4

Cefditoren Pivoxil Intermediates

4-Methyl-5-fomylthiazole 82294-70-0

Ceritinib Intermediates

5-Methyl-2-(1-methylethoxy)-4-(4-piperidinyl)benzenamine hydrochloride 1380575-45-0

4-Pyrimidinamine, 2,5-dichloro-N-[2-[(1-methylethyl)sulfonyl]phenyl]- 761440-16-8

Crizotinib Intermediates

3-[(1R)-(2,6- dichloro -3-fluorophenyl) ethoxy]-2- amino -5- bromopyridin 877399-00-3

1-(N-Boc-piperidine-4-ly)-boronic acid pinacol ester 877399-74-1


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Dabigatran Etexilate Intermediates

3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-

PROPIONIC ACID ETHYL ESTER

212322-56-0

N-(4-Cyano-phenyl)-glycine 42288-26-6

Hexyl chloroformate 6092-54-2

3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-

yl]carbonyl] pyridin-2-ylamino]propionic acid ethyl ester

211915-84-3

Daclatasvir Intermediates

(1aR,12bS)-8-Cyclohexyl-11-fluoro-N-((1-methylcyclopropyl)sulfonyl)-1a-((3-

methyl-3,8-diazabicyclo[3.2.1]oct-8-yl)carbonyl)-1,1a,2,2b-

tetrahydrocyclopropa[d]indolo[2,1-a][2]benzazepine-5-carboxamide

1235403-62-9

(2S,2'S)-di-tert-butyl 2,2'-(4,4'-([1,1'-biphenyl]-4,4'-diyl)bis(1H-iMidazole-4,2-

diyl))bis(pyrrolidine-1-carboxylate)

1007882-23-6

Dapagliflozin Intermediates

5-bromo-2-chlorobenzoic acid 21739-92-4

5-bromo-2-chloro-4'-ethoxydiphenylmethane 461432-23-5

(5-Bromo-2-chlorophenyl)(4-ethoxyphenyl) methanone 461432-22-4

Darifenacin Intermediates

2,3-Dihydrobenzofuranyl-5-acetic acid 69999-16-2

5-(2-Bromoethyl)-2,3-dihydrobenzofuran 127264-14-6

(S)-3-Hydroxypyrrolidine hydrochloride 122536-94-1


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3-(S)-(+)-(1-Carbamoyl-1,1-diphenylmethyl)pyrroloidine-L-(+)-tartarate 134002-26-9

Darunavir Intermediates


Phenylbutane

98737-29-2



102123-74-0



ester

165727-45-7

Dasatinib Intermediates

2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide 302964-24-5

Deferasirox Intermediates

4-Hydrazinylbenzoic acid 619-67-0

2-Hydroxybenzamide 65-45-2

Delafloxacin intermediates

1-(6-amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-[3-( 2-

methyl-1-oxopropoxy)-1-azetidinyl]-4-oxo-, ethyl ester

875712-90-6

1-(6-amino-3,5-difluoro-2-pyridinyl)-6-fluoro-1,4-dihydro-7-[3-(2-methyl- 1-

oxopropoxy)-1-azetidinyl]-4-oxo-, ethyl ester

442526-91-2

Benzenepropanoic acid, -[[(6-amino-3,5-difluoro-2-pyridinyl)amino]

methylene]-2,4,5-trifluoro- -oxo-, ethyl ester

875712-88-2

2,6-Diamino-3,5-difluoropyridine 247069-27-8

Dolutegravir Intermediates

1-(2,2-DiMethoxyethyl)-5-Methoxy-6-(Methoxycarbonyl)- 1335210-23-5

4-Oxo-1,4-Dihydropyridine-3-Carboxylic Acid3-(Benzyloxy)-4-Oxo-4H-Pyran-

2-Carboxylic Acid

1206102-08-0


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Dimethyl 3-(Benzyloxy)-4-Oxo-4H-Pyran-2,5-Dicarboxylate 1246616-66-9

Donepezil HCL Intermediates

5,6-dimethoxy-1-indanone 2107-69-9

4-pyridine carboxaldehyde 872-85-5

1-Benzyl-4-Piperidine carboxaldehyde 22065-85-6

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)-piperidine 120014-07-5

2,3-dihydro-5,6-dimethoxy-2-((piperidin-4-yl)methyl)inden-1-one HCL 120013-39-0

5,6-dimethoxy-2-(4-pyridylmethylene)-1-Indanone 4803-74-1

Donepezil Base 120014-06-4

Doripenem Intermediates

ACS-PNZ-PYRROLIDYL-(BOC)-NSO2NH2 491878-06-9

Dorzolamide Intermediates

2-Mercaptothiophene 7774-74-5

(6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one 147086-79-1

6-Methyl-4-oxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 120279-88-1

(6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one 7,7-dioxide 148719-91-9

(4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran-7,7-dioxide 147128-77-6

N-[(4S,6S)-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-

b]thiopyran-4-yl]acetamide

147200-03-1

Efavirenz Intermediates

Cyclopropyl Acetylene 6746-94-7

Cyclopropyl Methyl Ketone 765-43-5

Eldecalcitol Intermediates


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[(2Z)-2-[(3R,4R,5R)-3,5-bis[[(1,1-diMethylethyl)diMethylsilyl]oxy]-4-[3-[[(1,1-

di Methylethyl)di Methylsilyl]oxy]propoxy]-2-

Methylenecyclohexylidene]ethyl]diphenyl-

200636-54-0

Empagliflozin Intermediates

(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran 915095-94-2

2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone 32384-65-9

(3S)-3-[4-[(5-bromo-2-chlorophenyl)methyl]phenoxy]tetrahydro-furan 915095-89-5

Entecavir Intermediates

(1R,2S)-2-[(Phenylmethoxy)methyl]-3-cyclopenten-1-ol 188399-48-6

(1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-

methoxyphenyl)diphenylmethyl)amino)-9H-purin-9-yl)-2-

((benzyloxy)methyl)cyclopentanol

142217-78-5

6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-

methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-

amine

142217-80-9

2-Amino-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-

methylenecyclopentyl)-1H-purin-6(9H)-one

142217-81-0

Erlotinib Intermediates

6,7-bis-(2-methoxyethoxy)-4(3H)-quinazolinone 179688-29-0

4,5-bis-(2-methoxyethoxy)-2-nitrobenzonitrile 236750-65-5

4-chloro-6,7-bis-(2-methoxyethoxy)-4(3H)-quinazolinone 183322-18-1

Febuxostat Intermediates

Ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 161797-99-5


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Ethyl 2-(3-formy1-4-hydroxypheny1)- 4-methylthiazole-5-carboxylate 161798-01-2

Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate 161798-03-4

Ethyl 2-(3-cyano-4-isobutoxypheny1)-4-methyl-5-thiazolecarboxylate 160844-75-7

Fosamprenavir Intermediates

(2S,3S)-1,2-Epoxy-3-(Boc-amino)-4- Phenylbutane 98737-29-2



102123-74-0



ester

165727-45-7

Fulvestrant Intermediates 7 ,17 -7-[9-(4,4,5,5,5-pentafluoropentyl)thio]nonyl]estra- 1,3,5(10)- triene-

3-diol -17oxyethyl

875573-69-6

4,4,5,5,5-Pentafluoro-1-pentanethiol 148757-88-4

Gefitinib Intermediates

6-acetoxy-4-(3'-chloro-4'-fluoroanilino)-7-methoxyquinazoline 788136-89-0

2-nitro-4-methoxy-5-(3-chloropropoxy)benzonitrile 1315512-61-8

3,4-dihydro-7-methoxy-4-oxo-quinazolin-6-yl acetate 179688-53-0

4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 184475-71-6

6-hydroxy-7-methoxy-3H-quinazolin-4-one 179688-52-9

7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 199327-61-2

Gemcitabine Intermediates

2-Deoxy-2,2-difluoro-D-erythro-pentafuranous-1-ulose-3,5-dibenzoate 122111-01-7


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Ethyl (3R,S)-2,2-difluoro-3hydorxy-3-(2,2-

dimethlydioxolan-yl)propionate

95058-92-7

Glimepiride

3-ethyl-4-methyl-3-pyrroline-2-one 766-36-9

4-[2-(3-ethyl-4-methyl-2-oxo-pyrroline-1-carboxamido)-ethyl]] Benzene

sulfonamide

119018-29-0

Trans-4-methyl cyclohexyl amine 2523-55-9

Trans-4-methyl cyclohexyl isocyanate 32175-00-1

Glipizide Intermediates

5-Methylpyrazine-2-carboxylic acid 5521-55-1

Irbesartan Intermediates

2n-Butyl-1.3-Diazaspiro[4.4]non-1-en-4-one·HCl 151257-01-1

[1.1' -Biphenyl]-2-carbonitrile-4-[(2-butyl-4 -oxo-1.3- diazaspiro[4.4]non-1-en-

3-yl)methyl]

138401-24-8

Trityl Irbesartan 138402-10-5

Ibrutinib Intermediates

(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-

amine

1022150-12-4

4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine 330786-24-8

Imatinib Intermediates

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 152460-10-1

4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride 106261-49-8

Indacaterol Intermediates

5-(2R)-2-Oxiranyl-8-benzyloxy-2(1H)-quinolinone 173140-90-4

8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline 100331-89-3

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride 312753-53-0

Intedanib Intermediates(NEW)

Methyl 2-oxoindole-6-carboxylate 14192-26-8


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n-(4-aminopheny1)-n,4-dimethy1-1-piperazineacetamide 262368-30-9

Isavuconazole Intermediates

4-(2-Bromoacetyl)benzonitrile 20099-89-2

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-

yl)thiobutyraMide

368421-58-3

1-(2,5-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone 1157938-97-0

LCZ-696 Intermediates

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-

Methylpentanoic acid

1012341-50-2

AHU-377 149709-62-6

Levetiracetam Intermediates

(S)-2-Aminobutanamide hydrochloride 7682-20-4

Ledipasvir Intermediates

2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-(6-broMo-1H-benziMidazol-2-

yl)-, 1,1-diMethylethyl ester,(1R,3S,4S)-

1256387-74-2

(1R,3S,4S)-3-[6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-

benzimidazol-2-yl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid 1,1-

dimethylethyl ester

1256387-87-7

Lenalidomide Intermediates

Methyl 2-bromomethyl-3-nitrobenzoate 98475-07-1

2,6-Dioxopiperidine-3-ammonium chloride 24666-56-6

Lesinurad Intermediates

4-cyclopropylnaphthalen-1-aMine hydrochloride 1533519-92-4

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione 1533519-84-4


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5-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol 878671-96-6

Linagliptin Intermediates

1-Bromo-2-Butyne 3355-28-0

(R)-3-(Boc-Amino)piperidine 309956-78-3

(R)-3-Piperidinamine dihydrochloride 334618-23-4

3-Methylxanthine 1076-22-8

8-Bromo-3-methyl-xanthine 93703-24-3

2-(chloromethyl)-4-methylquinazoline 109113-72-6

8-bromo-7-(but-2-ynyl)-3-methyl-1H-purine-2,6(3H,7H)-dione 666816-98-4

8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-

quinazolinyl)methyl]-1H-purine-2,6-dione

853029-57-9

Lorcaserin Hydrochloride Intermediates

1-[ [ 2-(4-Chlorophenyl)ethyl] amino] -2-chlo

ropropane Hydrochloride

953789-37-2

Loxoprofen sodium Intermediates

Loxoprofen; 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoic acid 68767-14-6

Methyl 2-Cyclopentanone carboxylate 10472-24-9

2-(4-Bromomethyl)phenylpropionic acid 111128-12-2

Lurasidone Intermediates

(1R,2R)-1,2-Cyclohexanedicarboxylic acid 46022-05-3

(1R,2R)-1,2-Cyclohexanedimethanol 65376-05-8

3-(1-Piperazinyl)-1,2-benzisothiazole 87691-87-0

(1S,2S)-Cyclohexane-1,2-dimethanol 3205-34-3


APIs

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CAD Pharma Inc.

(R,R)-1,2-Bis(methanesulfonylloxy methyl) cyclohexane 186204-35-3

(3AR,4S,7R,7AS)4,7-Methano-1H-isoindole-1,3-(2H)-dione 14805-29-9

1-(1,2-Benzisothiazol-3-yl)piperazine hydrochloride 87691-88-1

Macitentan Intermediates

N-Propylsulfamide 147962-41-2

4,6-Dichloro-5-(4-bromophenyl)pyrimidine 146533-41-7

Memantine HCL

1-Bromo-3,5-dimethyladamantane 941-37-7

1 ,3-dimethyl adamantane 702-79-4

Methylphenidate HCl Intermediates

2-Phenyl-2-(2-piperidyl)acetic acid 19395-41-6

Moxifloxacin Intermediates

(4aS,7aS)-Octahydro-1H-pyrrolo[3,4-

b]pyridine

151213-40-0

Netupitant Intermediates

N-Methy1-4-(2-methylpheny1)-6-(4-methyl-1-piperaziny1)-3-pyridinamine 290297-25-5

2-(3,5-Bis(trifluoromethyl)pheny1)-2-methylpropionic acid 289686-70-0

Nintedanib Intermediates

Methyl oxindole-6-carboxylate 14192-26-8

N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide 262368-30-9

Obeticholic Acid Intermediates

6-Ethylchenodeoxycholic acid 459789-99-2

7-ketolithocholic Methyl ester 10538-59-7

(E)- -hydroxy-6-ethylidene-7-keto- -cholan-24-oic acid 1516887-33-4

3-alpha-Hydroxy-7-oxo-5-beta-cholanic acid 4651-67-6

Olaparib Intermediates


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CAD Pharma Inc.

4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-

fluorobenzyl)phthalazin-1(2H)-one

763113-22-0

2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid 763114-26-7

1-(Cyclopropylcarbonyl)piperazine hydrochloride 1021298-67-8

Olmesartan Medoxomil Intermediates

4-chloromethyl-5-methyl-1 ,3-dioxol-2-one 80841-78-7

Ethyl-4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-Carboxylate 144689-93-0

Trityl Olmesartan Ethyl Ester 189400-21-3

Trityl Olmesartan 761404-85-7

Trityl Olmesartan Medoxomil 144690-92-6

Olopatadine Intermediates

Isoxepac 55453-87-7

Oxybutynin HCl Intermediates

Oxybutynin Base 5633-20-5

a-Cyclohexyl-Mandelic acid Methyl ester 10399-13-0

4-(diethylamino)but-2-ynyl Aceate 22396-77-6

Palbociclib Intermediates

6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one 1016636-76-2

4-(6-aminopyridin-3-yl)piperazine-1-carboxylic 571188-59-5

Paliperidone Intermediates

6,7,8,9-Tetrahydro-3-(2-(4-(6-fluro-1,2-benzisoxazol-3-yl)-1-

piperidinyl)ethyl)-9-hydroxy-2-methyl-4H-pyrido[2,1-a]pyrimidin-4-one

144598-75-4

6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole hydrochloride 84163-13-3


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CAD Pharma Inc.

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-

a]pyrimidin-4-one

130049-82-0

Palonosetron Hydrochloride Intermediates

(S)-(-)-1,2,3,4-Tetrahedro-naphthoic acid 85977-52-2

(S)-3-Aminoquinuclidine dihydrochloride 119904-90-4

Pantoprazole Intermediates

2-Chloromethyl-3,4-Dimethoxy Pyridine HCl 72830-09-2

5-Difluoromethoxy-2-Mercapto-1H-Benzimidazole 97963-62-7

5-Difluoromethoxy-2-{[(3,4-Dimethoxy-2-Pyridinyl)Methyl]thio}-1H-

Benzimidazole

102625-64-9

Phenylephrine Intermediates

3-Hydroxy Acetophenone 121-71-1

-(N-Benzyl-N-Methylamino)-m-Hydroxy-Acetophenone HCl 71786-67-9

Pimobendan Intermediates

6-(3,4-Diaminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone 74150-02-0

Benzamide,N-[2-amino-4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-

pyridazinyl)phenyl]-4-methoxy-

74149-74-9

Pitavastatin Calcium

Methyl (3R)-3-(tert-butyldimethylsilyloxy)-

5-oxo-6-triphenylphosphoranylidene

hexanate

147118-35-2

Prasugrel

1-Cyclopropyl-2-(2-fluorophenyl)ethanone 150322-73-9

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4

Thie[3,2-c]pyridin-2(4H)-one,5,6,7,7a-tetrahydro hydrochloride 115473-15-9

Posaconazole Intermediates


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5-(2,4-Difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-

ylmethyl ester

149809-43-8

2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-

1-piperazinyl]phenyl]- 3H-1,2,4-triazol-3-one

184177-83-1

Raloxifene Intermediates

2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol 63676-22-2

Rasagiline Intermediates

Propargyl benzenesulfonate 6165-75-9

Rebamipide Intermediates

2-Amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propanoic acid(H2O.HCL) 5162-90-3

2-Amino-3-(1,2-dihydro-2-oxoquinoline-4-yl)propanoic acid(2H20.2HCL) 5162-90-3

4-Bromomethyl-1,2-Dihydroquinoline-2-One 4876-10-2

Diethyl [(4-Chlorobenzoyl)Amino]Propanedioate 81918-01-6

Diethyl2-(4-Chlorobenzamido)-2-[(2-Oxo-1,2-Dihydroquinolin-4-

yl)Methyl]malonate

1028268-32-7

Regorafenib Intermediates

4-Amino-3-fluorophenol 399-95-1

4-Chloro-3-(trifluoromethyl)phenyl isocyanate 327-78-6

N-methyl-4-chloropicolinamide 220000-87-3

Rimonabant Intermediates

2-Bromo-2',4'-dichloroacetophenone 2631-72-3

Rivastigmine tartrate

N-Ethyl-N-Methyl Carbamoyl Chloride 42252-34-6


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Intermediates

Regulatory Affairs




CAD Pharma Inc.

(S)-3-1(- Dimethylamino)ethylphenol 139306-10-8

Rivaroxaban Intermediates

5-Chlorothiophene-2-carboxylic acid 24065-33-6

4-(4-Aminophenyl)morpholin-3-one 438056-69-0

(S)-(+)-N-(2,3-Epoxypropyl)phthalimide 161596-47-0

1H-Isoindole-1,3(2H)-dione,2-[[(5S)-2-oxo

-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxaz olidinyl]methyl

446292-08-6

(4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl

)amino)phenyl]morpholin-3-one )

1252018-10-2

4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazo lidinyl]phenyl]-3-morpholinone

hydrochloride

898543-06-1

1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-hydr oxy-3-[[4-(3-oxo-4-

morpholinyl)phenyl]ami

no]propyl]-

446292-07-5

Rizatriptan Intermediates

4-Dimethylamino butyaldehyde dimethylacetal 19718-92-4

1-(4-HYDRAZINOBENZYL)-1H-1,2,4-TRIAZOLE 144035-22-3

Rocuronium Intermediates

(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol 119302-20-4

2a,3a-Epoxy-16b-(1-pyrrolidinyl)-5a-androstan-17b-ol 119302-19-1

2a,3a,16a,17a-Diepoxy-17b-acetoxy-5a-androstane 50588-22-2

Rosuvastatin Calcium Intermediates


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CAD Pharma Inc.

Rosuvastatin Calcium C-4 1540426-95-6



Rosuvastatin Calcium Z-7 147118-36-3

4-(4-Fluorophenyl)-6-Isopropyl-2- [(N-

Methyl-N-Methylsulfonyl) amino]-5-

Formylpirimidine

147118-37-4

Methyl(3R)-(tert-butyldimethylsilyloxy)-5-

oxo-6-

triphenylphosphoranylidenehexanoate

147118-39-6

Rosuvastatin Methyl Ester 147118-40-9

tert-Butyl rosuvastatin 355806-00-7

Methyl (3R)-3-(tert-butyldimethylsilyloxy)-

5-oxo-6-triphenylphosphoranylidene

hexanate

147118-35-2

Saquinavir Intermediates


Phenylbutane

98737-29-2



102123-74-0



ester

165727-45-7

Saxaliptin Intermediates

(1S,3S,5S)-3-(Aminocarbonyl)-2-

azabicyclo[3.1.0]hexane-2-carboxylic acid

tert-butyl ester

361440-67-7

(alphaS)-alpha-Amino-3-

hydroxytricyclo[3.3.1.13,7]decane-1-acetic

acid

709031-29-8

/361442-00-4(HCl)


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CAD Pharma Inc.

Boc-3-Hydroxy-1-adamantyl-D-glycine 361442-00-4

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide monomethanesulfonate 709031-45-8

(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide hydrochloride 709031-39-0

(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid

tert-butyl ester

361440-67-7

Silodosin Intermediates

1-[3-(benzyloxy)propy1]-5-formylindoline-7-carbonitrile 1375180-30-5

5-[(2R)-2-Aminopropy1]-1[3-(benzoyloxy)propy1]-2,3-dihydro-1H-indole-7-

carbonitrile (2R,3R)-2,3 -dihydroxybutanedioate

239463-85-5

2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate 160969-03-9

Sofosbuvir Intermediates

L-Alanine isopropyl ester hydrochloride 62062-65-1

GS-7977 1190307-88-0

2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 863329-66-2

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-

Methylethyl ester

1334513-02-8

Solifenacin Intermediates

(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline 118864-75-8

(R)-(-)-3-Quinuclidinol 25333-42-0

3-Quinuclidinone hydrochloride 1193-65-3


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CAD Pharma Inc.

Sumatriptan Succinate Intermediates

4-chlorobutyraldehyde dimethyl acetal 29882-07-3

4-Hydrazino-N-Methylbenzenemethanesulfonamide Monohydrochloride 88933-16-8

Sunitinib Intermediates

5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 253870-02-9

Telmisartan Intermediates Methyl ’-bromomethyl biphenyl-2-carboxylate 114772-38-2

2-n-Propyl-4-methyl-6-(1-methylbenzi midazole-2-ly) benzimidazole 152628-02-9

Teneligliptin Intermediates

(2S)-4-oxo-2-(3-thiazolidinylcarbonyl)-1-pyrrolidine carboxylicacid tert-butyl

ester

401564-36-1

1-(3-methyl-1-phenyl-1H-pyrazole-5-yl) piprazine 401566-79-8

Ticagrelor Intermediates

(1R,2S)-2-(3,4-

Difluorophenyl)cyclopropanamine

220352-38-5

(1R,2S)-2-(3,4-

Difluorophenyl)cyclopropanaminium (2R)-

hydroxy(phenyl)ethanoate

376608-71-8

2-((3aR,4S,6R,6aS)-6-amino-2,2-

dimethyltetrahydro-3aH-

cyclopenta[d][1,3]dioxol-4-yloxy)ethanol L-

tataric acid

376608-65-02

4,6-Dichloro-2-(propylthio)pyrimidin-5-amine 145783-15-9

Torasemide

4-Hydroxypyridien 626-64-2

4-(3-methylphenyl) amino-3-pyridine sulfonamide 72811-73-5

Trelagliptin Intermediates


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CAD Pharma Inc.

2-Cyano-5-Fluorobenzyl Bromide 421552-12-7

6-chlorouracil-3-Methyl 4318-56-3

Valsartan Intermediates

N-[[(2' -cyano(1.1' -biphenyl)-4-yl)methyl] methyl ester]-L -valine·HCl 482577-59-3

Trityl Valsartan 195435-23-5

Valsartan Methyl ester 137863-17-3

Vilazodone Intermediates

Ethyl 5-nitrobenzofuran-2-carboxylate 69604-00-8

5-aminobenzofuran-2-carboxylic acid 42933-44-8

3-(4-Chlorbutyl)-1H-indol-5-carbonitril 143612-79-7

5-(1-piperazinyl)benzofuran-2-carboxamide 183288-46-2

5-Cyanoindole 15861-24-2

Vildagliptin Intermediates

L-Prolinamide 7531-52-4

3-Amino-1-adamantanol 702-82-9

(2S)-1-chloroacetyl-2-pyrrolidine carbonitrile 207557-35-5

Vonoprazan fumarate Intermediates

TAK-438 1260141-27-2

5-(2-Fluorophenyl)-1H-pyrrole-3-carbaldehyde 881674-56-2

1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester 881674-06-2

Vortioxetine Intermediates

4-(2-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 494773-35-2

1-BOC-PIPERAZINE 57260-72-7


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CAD Pharma Inc.

Zolmitriptan Intermediates

4-Dimethylamino butyaldehyde diethyl acetal 1116-77-4

(4R)-4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one 139264-17-8

(S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone 152305-23-2

Zopiclone Intermediates

4-methyl-1-piperazinecarbonyl chloride

hydrochloride

55112-42-0


Documents

Product List - CAD Pharmacadpharma.com/pdf/intermediates.pdf · 2016. 1. 4. · 2- (5 -Bromo-2-methylbenzyl)-5- (4 -fluorophenyl)thiophene 1030825- 20 -7 5-Bromo-2-chlorobenzoic acid