PUD Outline

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    UD

    A. PUD- lesion of GI mucosa characterized by erosion from HCL & pepsin

    1. Stomach protected by prostaglandins- increase stomachs resistance to ulceration

    B. ETIOLOGY

    1. Disruption mucosal barrierback diffusion HCL & pepsininflammation & cellular

    destruction-->histamine release more HCL & pepsin release

    2. Inflammatory agents- bile salts, NSAIDS, H. Pylori, acids, ischemia, & corticosteroids

    C. GASTRIC ULCER

    1. Decrease/N HCL & delayed gastric emptying

    2. Females 55-60

    3. Burning, gaseous pain high epigastrum, pain empty stomach, 1-2hrs after eating, aggravated

    by food

    D. DUODENAL ULCER

    1. High HCL and increased gastric emptying

    2. Males 34-45

    3. Muscularis layer, scar4. Burning, cramp like pain mid-epigastrum, 90min-3hrs after eating, mid-morning, afternoon,

    and @ nite (1-2a.m)

    5. Relief w/ antacids & H2 blockers

    E. DEFINITIVE DX: EGD

    F. RISK FACTORS

    1. NSAIDS

    2. Smoking

    3. Alcohol

    4. H. Pylori5. Caffeine

    6. Genetic predisposition

    7. Psychologic stress

    8. Altered gastric acid & serum gastric levels

    G. DIAGNOSTICS

    1. UPPER GI ENDOSCOPY-r/o gastric cancer

    2. H. Pylori testing blood, breath, urine, tissues-IgG, IgM

    3. CBC

    4. Serum amylase

    5. Urinalysis

    6. Barium swallow

    7. Liver enzymes: AST, ALT, bilirubin

    8. Serum e-lytes

    9. Gastric analysis- Zollinger-ellison syndrome

    10. Guaiac stool

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    H. S/S PUD

    1. Gastric/duodenal pain

    2. Melena

    3. Vomiting

    4. Orthostatic VS

    5. Deficient fluid volume

    6. Decreased HgB & HCT

    7. Dyspepsia

    8. Anorexia & weight loss

    I. COMPLICATIONS PUD

    1. Hemorrhage

    2. Obstruction-long hx ulcer pain, worsens as day progresses, relieved by vomiting/belching

    (foul odour), weight loss, thirst, unpleasant taste mouth, constipation, swelling upper

    abdomen, loud & visible peristalsis

    3. Perforation- rigid board like, guarding, absent bowel sounds, N&V

    4. Intractable dx

    J. MEDICAL/SURGICAL

    1. ADEQUATE REST

    2. DIETARY THERAPY

    i. Avoid foods cause pain including milk & creamsii. 6 meals daily, decrease roughageraw fruits & veggies

    iii. No aspirin or NSAIDS

    3. Smoking cessation 7 avoid alcohol consumption

    4. DRUG THERAPY

    i. Antacids

    ii. H2 blockers or PPIs

    iii. Antibiotic therapy

    1. Metronidazole (Flagyl)

    2. Tertracycline

    3. Amoxicillin

    iv. Cholinergics- Metoclopranamide (Reglan)

    v. Cytoprotective- Bismuth Subsalicylate (Pepto-bismol), Carafate (Sulcralfate)

    vi. Tricyclic antidepressants

    5. STRESS MANAGEMENT

    6. ACUTE INTERVENTIONS

    i. No complications

    1. NPO

    2. NG w/ sxn

    3. Adequate rest

    4. Smoking cessation

    5. IV fluids6. Drug therapy

    ii. w/ complications

    1. NPO

    2. NG sxn- cont aspiration obstruction

    3. Bed rest

    4. IV fluids: albumin, ringers lactate, PRBC- perforation & hemorrhage maintain

    or increase rate

    5. Gastric lavage (ice NS)

    6. Repair perforation

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    7. SURGERY

    i. Gastroenterostomy

    ii. Closure w/ omentum graft

    iii. Vagotomy w/without pyloroplasty

    iv. BilrothI/II

    1. Post-op

    a. Patency NG tube

    b. Fluid & e-lyte balancec. Assess acute gastric dilation

    d. Assess dumping syndrome

    e. Manage dumping syndrome

    i. Decrease amt food given

    ii. High protein & fat

    iii. Admin pectin powder

    iv. Admin semi-recumbant/recumbent

    v. Lay flat after eating

    vi. Admin sedative & antispasmotic

    f. Check alkaline reflux gastritis

    g. Assess delayed gastric emptying

    h. Assess afferent loop syndrome

    i. Admin vit B12, folic acid, Fe3+ supps

    K. POST-OP COMPLICATIONS

    1. Dumping syndrome

    2. Postpranadial hypoglycemia

    3. Bile reflux gastritis

    L. NURSING INTERVENTIONS

    1. HEALTH PROMOTION

    i. Id those at risk

    ii. Encourage pts take drug w// milk or foodiii. Teach report s/s gastric irretation

    2. Acute interventions

    i. Approach in calm manner

    ii. VSq15-30min

    iii. NPO (stop all oral when perforation/hemorrhage)

    iv. NG w/ sxn

    1. Hemorrhage & decompression- cont sxn & decompression

    2. Obstruction- cont aspiration, clamp

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    3. HOME CARE

    i. Explain dietary modification

    ii. Smoking cessation, avoidance alcohol

    iii. Avoid OTC substitutions of meds

    iv. Take all meds as prescribed

    v. Teach report: N&V, increased epigastric pain, bloody emesis or tarry stools