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7/30/2019 PUD Outline
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UD
A. PUD- lesion of GI mucosa characterized by erosion from HCL & pepsin
1. Stomach protected by prostaglandins- increase stomachs resistance to ulceration
B. ETIOLOGY
1. Disruption mucosal barrierback diffusion HCL & pepsininflammation & cellular
destruction-->histamine release more HCL & pepsin release
2. Inflammatory agents- bile salts, NSAIDS, H. Pylori, acids, ischemia, & corticosteroids
C. GASTRIC ULCER
1. Decrease/N HCL & delayed gastric emptying
2. Females 55-60
3. Burning, gaseous pain high epigastrum, pain empty stomach, 1-2hrs after eating, aggravated
by food
D. DUODENAL ULCER
1. High HCL and increased gastric emptying
2. Males 34-45
3. Muscularis layer, scar4. Burning, cramp like pain mid-epigastrum, 90min-3hrs after eating, mid-morning, afternoon,
and @ nite (1-2a.m)
5. Relief w/ antacids & H2 blockers
E. DEFINITIVE DX: EGD
F. RISK FACTORS
1. NSAIDS
2. Smoking
3. Alcohol
4. H. Pylori5. Caffeine
6. Genetic predisposition
7. Psychologic stress
8. Altered gastric acid & serum gastric levels
G. DIAGNOSTICS
1. UPPER GI ENDOSCOPY-r/o gastric cancer
2. H. Pylori testing blood, breath, urine, tissues-IgG, IgM
3. CBC
4. Serum amylase
5. Urinalysis
6. Barium swallow
7. Liver enzymes: AST, ALT, bilirubin
8. Serum e-lytes
9. Gastric analysis- Zollinger-ellison syndrome
10. Guaiac stool
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H. S/S PUD
1. Gastric/duodenal pain
2. Melena
3. Vomiting
4. Orthostatic VS
5. Deficient fluid volume
6. Decreased HgB & HCT
7. Dyspepsia
8. Anorexia & weight loss
I. COMPLICATIONS PUD
1. Hemorrhage
2. Obstruction-long hx ulcer pain, worsens as day progresses, relieved by vomiting/belching
(foul odour), weight loss, thirst, unpleasant taste mouth, constipation, swelling upper
abdomen, loud & visible peristalsis
3. Perforation- rigid board like, guarding, absent bowel sounds, N&V
4. Intractable dx
J. MEDICAL/SURGICAL
1. ADEQUATE REST
2. DIETARY THERAPY
i. Avoid foods cause pain including milk & creamsii. 6 meals daily, decrease roughageraw fruits & veggies
iii. No aspirin or NSAIDS
3. Smoking cessation 7 avoid alcohol consumption
4. DRUG THERAPY
i. Antacids
ii. H2 blockers or PPIs
iii. Antibiotic therapy
1. Metronidazole (Flagyl)
2. Tertracycline
3. Amoxicillin
iv. Cholinergics- Metoclopranamide (Reglan)
v. Cytoprotective- Bismuth Subsalicylate (Pepto-bismol), Carafate (Sulcralfate)
vi. Tricyclic antidepressants
5. STRESS MANAGEMENT
6. ACUTE INTERVENTIONS
i. No complications
1. NPO
2. NG w/ sxn
3. Adequate rest
4. Smoking cessation
5. IV fluids6. Drug therapy
ii. w/ complications
1. NPO
2. NG sxn- cont aspiration obstruction
3. Bed rest
4. IV fluids: albumin, ringers lactate, PRBC- perforation & hemorrhage maintain
or increase rate
5. Gastric lavage (ice NS)
6. Repair perforation
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7. SURGERY
i. Gastroenterostomy
ii. Closure w/ omentum graft
iii. Vagotomy w/without pyloroplasty
iv. BilrothI/II
1. Post-op
a. Patency NG tube
b. Fluid & e-lyte balancec. Assess acute gastric dilation
d. Assess dumping syndrome
e. Manage dumping syndrome
i. Decrease amt food given
ii. High protein & fat
iii. Admin pectin powder
iv. Admin semi-recumbant/recumbent
v. Lay flat after eating
vi. Admin sedative & antispasmotic
f. Check alkaline reflux gastritis
g. Assess delayed gastric emptying
h. Assess afferent loop syndrome
i. Admin vit B12, folic acid, Fe3+ supps
K. POST-OP COMPLICATIONS
1. Dumping syndrome
2. Postpranadial hypoglycemia
3. Bile reflux gastritis
L. NURSING INTERVENTIONS
1. HEALTH PROMOTION
i. Id those at risk
ii. Encourage pts take drug w// milk or foodiii. Teach report s/s gastric irretation
2. Acute interventions
i. Approach in calm manner
ii. VSq15-30min
iii. NPO (stop all oral when perforation/hemorrhage)
iv. NG w/ sxn
1. Hemorrhage & decompression- cont sxn & decompression
2. Obstruction- cont aspiration, clamp
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3. HOME CARE
i. Explain dietary modification
ii. Smoking cessation, avoidance alcohol
iii. Avoid OTC substitutions of meds
iv. Take all meds as prescribed
v. Teach report: N&V, increased epigastric pain, bloody emesis or tarry stools