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Hamza Ali Babiker
Address: 87 Comsiton Rd, Edinburgh, EH10 6AG, UK
Current address: Biochemistry Department, College of Medicine & Health Sciences,
PO Box 35, Postal code 123, Al-Khod, Sultanate of Oman.
Qualifications: B.Pharm, M.Sc. (Biochemistry), PhD (Genetics)
Present posts:-
Professor, Biochemistry Department, Faculty of Medicine, Sultan Qaboos,
University, Oman
Senior Honorary Research Fellow, Institutes of Evolution, Immunology and
Infection Research, Edinburgh University, Edinburgh, United Kingdom, UK
AWARDS:
1. Best Researcher Award, Faculty of Medicine, Sultan Qaboos University, Oman,
May 2009.
2. VIP Award, Wellcome Trust/ Edinburgh University, October 2003 for 12
months to bridge research funds and retain senior researchers.
3. Research Development Award in Tropical Medicine. Wellcome Trust, October
1993.
4. British Council Training Award for PhD studies in UK, March 1989.
TEACHING
Graduate students.
(A) Sultan Qaboos University, Faculty of Medicine and Health Science
Advance Molecular Biology (BIOC 6003), 3 credits, 2007-2012, course coordinator,
The course emphasises the principles of; a) gene structure and function, gene cloning
b) analysis of genes and effect of mutations on function. c) different approaches to
detect mutations or polymorphism in genes and d) application of DNA technology
(B) Courses for graduate students outside SQU, 1999 to present
1. 7th -15th January 1995 “Application of molecular techniques for studies on
parasitic diseases”, Institute of Endemic Diseases, Faculty of Medicine, University of
Khartoum, Sudan.
2. 15th -24th January 1996 “Application of molecular techniques for studies on
parasitic diseases”, Institute of Endemic Diseases, Faculty of Medicine, and University
of Khartoum, Sudan.
3. 13th -November-1st December 2000 "Interregional Training Course on Molecular
Biology Techniques and Radionuclide Tracers in the Control of Infectious Diseases",
Institute of Molecular Biology and Genetics, Mahidol University, Bangkok, Thailand.
4. 10th April to 23rd April, 2002, Detection of drug-resistance in malaria and
Tuberculosis, Biotechnology Centre, University of Yaounde, Cameron.
5. 26st November to 7th December 2001, Use of Radionucide Tracers in the Control of
Drug Resistant Malaria". Malaria Research and Training Centre Faculte de Medicine,
de Pharmacie et d’Odoto-Stomatologie, Universite du Mali, Bamako, Mali
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6. 11th -18th January 2007, Evolution of drug resistance in malaria parasites. Tropical
Medicine Research Institute, Khartoum, Sudan.
Undergraduate students
(A). Sultan Qaboos University, Faculty of Medicine & Health Science 2004-present
Curriculum development. I developed course 1 & 2 in the below list, and
contributed significantly to restructuring of course 3, part of a new curriculum,
initiated in 2009 in the college of Medicine and Health Sciences, SQU.
1. Research Methodology (MED1 4202) 2 Credits
2. Student Project – (MEDI 5302) 3 Credits
These courses introduce students to biomedical research through research-
based learning activities. The course covers concept and fundamentals of
research methodology and analytical skills through lectures, tutorials and hands
on practice through the planning and implementation of a research project.
3. Molecular biology and principles of genetics (MEDI3101) 3 credits. This
course introduces fundamental aspects of molecular biology and genetics in
medicine, and their impact in health and disease. Current views and new
concepts relating to diagnosis, prognosis, prevention and treatment of diseases
are highlighted.
Course coordination.
1. Molecular biology and principles of genetics (MEDI3101) 3 credits, 2004-
present
2. Research Methodology (MED1 4202) 2 Credits - 2009- present
3. Student Project – (MEDI 5302) 3 Credits – 2010-present
Contribution to other courses
1. Biochemistry for Nursing (NURS2032) 3 Credits – 2013-present,
2. Respiratory System (SYST2154) 3 credits, 2004-2008
3. Urinary System (SYST2156) 3 credits, 2004-2008
4. Alimentary system (SYST2014) 3 credits, 2004-2007
5. Haemopoeitic and lymphoid vascular system (SYST2010) 3 credit, 2004-
2007
6. Applied Basic Medical Sciences (SYST3111) 3 credits, 2005-to-2006
Student advising
2010-2011: 9 students
2011-2012: 16 students
2012-2013: 26 students
2014-2014: 25 student
2015-2016: 25 students
2017-2018: 26 students
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Supervision of undergraduate research projects:
1. Saif Al Rahdi ID 115224. Mutations associated with resistance to the anti-
Tuberculosis (TB) drug rifampicin
2. Mohamed Al Ghaithi ID 115384. Mutations associated with resistance to the
anti-Tuberculosis (TB) drug rifampicin
3. Huriya Darwish Saleh Al-Balushi, ID:105309, Medical Students' Perceptions
of Undergraduate Research Module in Sultan Qaboos University
4. Fatema Said AL Habsi, ID# 106355. Impact of learning style on perception of
medical undergraduate research
5. Ameera Khlafan Al-Rahbi ID: 107452. Molecular characterization of drug
resistant Mycobacterium tuberculosis complex in Oman”
6. Kawther Abdullah Al-Jassasi ID 96958, project title “Comparison between
three molecular methods for detection of asymptomatic malaria in Oman”
7. Maymona Salim Alrubkhi ID: 90102, project title “Analysis of mutations in
k13- propeller and other genes implicated in artemisinin resistance among
Plasmodium falciparum isolates in Sudan”
8. Muna Ali Ahmed Alshahri ID 92250 , Project title “Evaluation of malaria
Loop mediated isothermal amplification (LAMP) assay for diagnosis of malaria
in asymptomatic carriers in the Sultanate of Oman?
9. Kawther Abdullah Humaid Al-Jassasi, ID 96958, Project title “Evaluation of
malaria Loop mediated isothermal amplification (LAMP) assay for diagnosis of
malaria in asymptomatic carriers in the boarder between Yemen and Oman?”
10. Huda Said AL.Rajhi, ID 93582, project title “Dynamics of mycobacterium
tuberculosis (MTB) haplotypes among Omanis and non- Omanis”
11. Wafa Abdullah AL.Belushi, ID 93522, project title “Distribution of multidrug-
resistant Mycobacterium tuberculosis genotypes among Omanis and non-
Omanis”
12. Ahmed Ashraf Abdel wahed Naiem: project title “Characterization of
chloroquine resistance genes of the malaria parasite Plasmodium falciparum”
13. Ahmed Mohamed Saif Al-Hosni ID 89020 project title “Characterization of
antifolate antimalarial drug resistant genes in Plasmodium falciparum in Al-
Buraimi & Al-Ain”
14. Manal Mohammed Hamed Al-Busaidi: ID 86185, project title “Polymorphism
of Adenosine A2A Receptor (ADORA2A) Gene among Omanis and its possible
association with Human Huntingtin (HTT) Gene and lymphoma”
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15. Fatma Mohammed Al-Hajri, ID:89210: Project title “Size polymorphism of
CAG repeats of Huntington’s gene among healthy Omanis”
16. Amani Khalifa Al-Dhuhli. ID:85429, project title: Characterization of
antifolate antimalarial drug resistant genes in Al-Jazirah in central Sudan
17. Manal Salim Al-Aufi. ID: 85976 , Project title “Characterization of antifolate
antimalarial drug resistant genes in Jazan in Saudi Arabia”
(B). University of Edinburgh 1994- 2004
Faculty of Science, BSc
Graduation research projects for final year students. This involves designing of
research projects, sessions of discussion on the theme of research and supervision of
laboratory work. In addition it involves marking of the project and evaluation of the
student’s performance. Between 1994 and 2004 I supervised 10 graduation research
projects.
Faculty of Medicine, elective BSc, Med Sci course
Supervision of graduation research projects for final year elective B.Sc., Med Sci
students.
This involves designing of projects, session of discussion on the theme of research and
supervision of laboratory work and writing up of a thesis. In addition it involves
marking of the project and evaluation of the student’s performance. Between 1998 and
2004 I supervised 3 graduation projects.
Supervision of graduate students:
PhD students
Current
1. Sara Al-mahruqi, Thesis title ”Molecular genomics of Mycobacterium
tuberculosis in Oman.2018
2. Hoyam Awad Mahgoub, Thesis title “Expression profile of gametocyte specific
protein genes of Theileria lestoquardi. (2014-current)
Completed PhD theses.
1. Mohamed Hassan Abdelrahim, Thesis title “Genetic diversity, drug resistance and
transmission potential of imported Plasmodium vivax in Arab Gulf country and
areas of origin in eastern Africa and India. Jan 2019, College of Medicine and
Health Sciences, Sultan Qaboos University, Oman. Co-supervisor
2. Salama Salim Al-Hamidhi, Thesis title “Population genetic structure of Theileria
annulata and T. lestoquardi in Oman. Sep 2017, College of Medicine and Health
Sciences, Sultan Qaboos University, Oman. Main supervisor
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3. Amal Azhari Gadallah, Thesis title “Effect of season, parasite multiplicity and drug
resistance on gametocytogenesis among asymptomatic Plasmodium falciparum
carriers”. Feb 2015, College of Medicine and Health Sciences, Sultan Qaboos
University, Oman. Main supervisor
4. Amani Ahmed, PhD thesis title “Population genetics and drug resistance indices of
Plasmodium falciparum in geographically separated areas in Sudan, following a
decade of scale up of control measures. October 2014. Khartoum University,
Sudan, Main supervisor
5. Amany Kheir. PhD thesis title “Factors influencing evolution of anti-malarial drug
resistance in Plasmodium falciparum in Sudan and The Gambia". April 2011.
Uppsala University, Sweden. External supervisor
6. Safa Jamal-Eldin. PhD thesis title: The dry season Plasmodium falciparum
gametocytes In an area of seasonal transmission in eastern Sudan: implication fir
malaria control. April 2006. Faculty of Science, University of Khartoum, Sudan.
External supervisor
7. Eltayeb Ali, PhD Thesis title: The impact of antimalarial treatments on in vivo and
in vitro production of Plasmodium falciparum gametocytes in an area of seasonal
transmission in eastern Sudan. May 2005. Ph.D thesis, Postgraduate Medical
studies Board, University of Khartoum, Sudan. External supervisor
8. Abdel-Muhsin Abdel-Gadir Abdel-Muhsin. PhD Thesis title “Dynamics of
Plasmodium falciparum drug resistance genes in some areas of seasonal malaria
transmission in Sudan. February 2004. Postgraduate Medical studies Board,
University of Khartoum, Sudan. External supervisor
9. Amel Osman Abdel-Wahab Osman. PhD thesis title: Plasmodium falciparum
gametocyte persistence and within-host dynamics in an area of unstable
malaria in Eastern Sudan – Gedaref. Nov. 2004. Postgraduate Medical studies
Board, University of Khartoum, Sudan. External supervisor
MSc Students
Completed MSc theses
1. Abir Omar Al-Rumhi. ID 87142. Genetic diversity and transmissibility of
imported P. falciparum into the malaria-free state of Qatar. April 2018, College of
Medicine and Health Sciences, Sultan Qaboos University, Oman.
Role: Main supervisor
2. Detection of Plasmodium falciparum resistance genes associated with chloroquine
and Fansidar in south Khartoum and Eastern Sudan. 2017. Institute of Endemic
Diseases, University of Khartoum, Sudan,
Role: Co-supervisor
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3. Esra Mukhtar Awad Mohammed, ID 86824, thesis title “Genetic structure of
Plasmodium vivax in Sudan based on global mitochondrial genome”, June 2016,
College of Sciences, Sultan Qaboos University, Oman.
Role: Co-supervisor
4. Amira Al-Fahdi, ID 86824, thesis title “Phylogenetic analysis of Theileria
lestoquardi in Oman”, Aug 2015, College of Medicine and Health Sciences,
Sultan Qaboos University, Oman.
Role: Main supervisor
5. Sara Hamad Al-Mhrogi ID 25434 thesis title “Genetic structure of
Mycobacterium tuberculosis in Oman” Jan 2015, College of Medicine and Health
Sciences, Sultan Qaboos University, Oman.
Role: Main supervisor
6. Abeer AlZubaidi. Thesis title “Genetic structure of Mycobacterium tuberculosis in
Oman”. Sept 2014, College of Medicine and Health Sciences, Sultan Qaboos
University, Oman.
Role: Main supervisor
7. Salama Salim Al-Hamidhi. Thesis title “Genetic diversity of Plsmodium
falciparum in Yemen and distribution of antimalarial drug resistance genotypes”.
Dec 2012, College of Medicine and Health Sciences, Sultan Qaboos University,
Oman.
Role: Main supervisor
8. Najma Al-Kharousi, Thesis title "Effect of Elagic acid on cisplatin-induced
nephorotoxicity in rats". August 2011. College of Medicine and Health Sciences,
Sultan Qaboos University, Oman.
Role: Main supervisor
9. Muna Ali Masoud Al-Rubkhi, Thesis title "Molecular detection and identification
of Theileria species in sheep in Oman" June 2011, College of Medicine and Health
Sciences, Sultan Qaboos University, Oman.
Role: Main supervisor
10. Nasser Al-Araimi Thesis title: "A study on the genetic diversity of Omani goats
using microsatellites". July 2011, College of Agricultural and Veterinary Sciences,
Sultan Qaboos University, Oman
Role: Co-supervisor
11. Metab Al-Ghafri Thesis title: "The potential association of BRCA2 variation with
male breast cancer in Omani cases". July 2011, College of Science, Sultan Qaboos
University, Oman
Role: Co-supervisor
12. Aisha Al-Busaidi Thesis title: "Screening for p53 mutations using archival material
in an Omani cohort with diffuse large B-cell lymphoma". March 2011, College of
Medicine and Health Sciences, Sultan Qaboos University, Oman
Role: Co-supervisor
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13. Sheikha Al-Harthy Thesis title: "The putative regulation of K-Ras/B-Raf pathway
by Soc1/2 protein in colon cancer cell lines". September 2011, College of
Medicine and Health Sciences, Sultan Qaboos University, Oman
Role: Co-supervisor
14. Zainab Salam Al-Hashami, Thesis title "Population structure of Plasmodium
falciparum and spread of chloroquine resistance in Saudi Arabia" December 2010,
College of Medicine and Health Sciences, Sultan Qaboos University, Oman.
Role: Main supervisor
15. Hissa Al-Farsi, Thesis title: "Genetic diversity and origin of Sulfadoxine-
pyrimethamine resistant Plasmodium falciparum in Jazan area, Saudi Arabia".
October 2010, College of Medicine and Health Sciences, Sultan Qaboos
University, Oman
Role: Main supervisor
16. Badria Said Al-Sawai, Thesis title: Association of polymorphisms of cytokines
(IL10 and TNF) genes and MTHFR gene and DLBCL among patients in Oman.
August 2009, College of Medicine and Health Sciences, Sultan Qaboos University,
Oman.
Role: Main supervisor
17. Salma Mahmmed Farag Als-saai, Thesis title: Origin of pyrimethamine resistance
among Plamsodium falciparum in eastern Sudan. August 2007, College of
Medicine and Health Sciences, Sultan Qaboos University, Oman.
Role: Main supervisor
18. Khanssa Ali Nassir, Thesis title “Impact of genetic complexity on longevity and
gametocytogenesis of Plasmodium falciparum during the dry and transmission-free
season of eastern Sudan”. April 2003. Institute of Cell, Animal and Population
Biology, Edinburgh University, UK. (Supervisor)
19. Nadine Randle, Thesis title “Reverse transcription PCR (RT-PCR) for the
detection and monitoring longevity of gametocytes of the malaria parasites
Plasmodium chabaudi:” April 2002, Institute of Cell, Animal and Population
Biology, Edinburgh University, UK. (Co-supervisor)
20. Mona Hamid Mahmoud. Thesis title: Molecular typing of chloroquine resistance in
Khartoum area. 2002. Postgraduate Medical studies Board, University of
Khartoum. (Co-supervisor)
21. Amel Hamad. Thesis title: Epidemiology of malaria in eastern Sudan. 1999,
Postgraduate Medical studies Board, University of Khartoum. (Co-supervisor)
22. Amel Osman Abdel-Wahab. Thesis Title: Comparative diagnosis and antigenic
diversity of Plasmodium falciparum in Eastern Sudan. June 1999, Postgraduate
Medical studies Board, University of Khartoum. (Co-supervisor)
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23. Abdel-Muhsin Abdel-Gadir . Thesis title: Survival and genetic complexity of
Plasmodium falciparum during the dry season of eastern Sudan. 1996,
Postgraduate Medical studies Board, University of Khartoum. (Co-supervisor)
Thesis examination:
1. Chair examination committee, MSc student Noor Saeed Rahall ID 114104/15,
project title “Determination of LDL cholesterol score in patients with familial
hypercholesterolemia”. Department of Biochemistry, College of Medicine, 16th
July 2018
2. Chair examination committee, PhD student Ibtsam Mustafa Al-Lawati ID
271/12, project title “ ”. Department of Physiology, College of Medicine, 4th July
2017
3. Externa; examiner: PhD: Student Name Omar Abdullah Ali Bamaga
(MHA100059) Thesis Title “Molecular epidemiology of malaria and detection of
anti-malarial drug resistance- associated marker (pfcrt, pfmdr1, pfdhfr and
pfdhps) in Hadramout Governorate, Yemen. Faculty of Medicine, University of
Malaya, Kuala Lumpur, Malaysia. Dec 2016
4. Chair examination committee, MSc student Mawiyah Hassan AlJabri, project
title “The influence of TLR9 single nucleotide polymorphisms on systemic lupus
erythematosus among Omani population ”, Department of Microbiology and
Immunology, College of Medicine, 16th June 2016
5. Chair examination committee, MSc student Zainab Juma Al-Lawati, project
title “Epidemiology of human papilloma virus (HPV) infection and genotyping
distribution among women attending Sultan Qaboos University Hospital and
Royal Hospital ”, Department of Microbiology and Immunology, College of
Medicine, 29th Feb 2016
6. Chair examination committee, MSc student Maryam Belarab Suleiman Al-
Suleimania, project title “Studies on morphology and functional expression of
transient receptor potential vanlloid-4 channel in the mesenteric artery of
hypertensive rates ”, Department of Physiology, College of Medicine, 28th Jan
2016
7. Chair examination committee, MSc student Abdullah Jathlan AlAni, project
title “Assessment of adherence to antihypertensive drugs using pharmacy refill
rate and self-report questionnaire in hypertensive patients attending Sultan
Qaboos University Hospital”, Pharmacology Department, College of Medicine,
17th Jan 2016
8. External examiner, 1st year appraisal, PhD student Ms Amal AlSAbahi, project
title “Synthesis, structure and photophysical characterization of naphthyl-
substituted pyrazoline fluorogenic labels for pre-column derivatization and
optoelectronic applications”. College of Science, SQU, 7th Sep 2015.
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9. Chair examination committee, MSc student Thamina Khalfan Mohmmed Al-
Rahbi, project title “Usage of two non-steroidal anti-inflammatory drugs in adult
patients at Sultan Qaboos university Hospital”, College of Medicine, 6th Sep 2015.
10. Chair examination committee, MSc student, Naeema Soud AYarubi, project
title “Autozygosity mapping of uncharacterised autosomal recessive genetic
condition in Omani families”, College of Medicine, 3rd Sep 2015.
11. External examiners. MSc thesis
Student: Norah Al Musri . Thesis title: Study of vitamin D levels and vitamin D
binding protein (DBP) and vitamin D receptor (VDR) polymorphisms in relation
to adults’ obesity and dyslipidemia in Bahrain. College of Medicine and Medical
Sciences, Arabian Gulf University, Bahrain. Feb 2015.
12. External examiners. MSc thesis
Bauthaina Saif Al-Dhahli ID 81854 (MSc). Thesis title “Apoptosis induction in
cancer by Marine Coral extracts” 18th Sep 2014, College of Medicine and Health
Science, Sultan Qaboos University, Oman
13. External examiners. MSc thesis
Fawziya Ahmed Al-Yafei (MSc). Thesis title “SNPs in TLRs 4, 7 & 9 among
Omani patients with AIDS”. 10th June 2013, College of Medicine and Health
Science, Sultan Qaboos University, Oman.
14. External examiners. MSc thesis
Muna Mohammed Al-Habsi (MSc), thesis title “A study of the genetic causes of
progressive myoclonic epilepsy in six families in Oman”. 9th May 2013, College
of Science, Sultan Qaboos University, Oman.
15. External examiners. MSc thesis
Bushra Abdul Hussain Al-Lawatia (MSc). Thesis title “Studies on prevalence and
characterization of methicillin resistance Staphylococcus aureus (MRSA) at
Sultan Qaboos University Hospital”. 10th June 2013, College of Medicine and
Health Science, Sultan Qaboos University, Oman.
16. External examiners. PhD thesis
Maha Alhadi (PhD) Thesis title “Genotypes of drug resistance Plasmodium
falciparum in eastern Sudan” College of Medicine, Khartoum University, Sudan,
June 2007.
Sponsored post-doc fellows:
Dr Salama Salim Al-Hamidhi, 2017-presesnt
Dr Badar Al-Qamashoui (2014-2017), SQU, (part-time)
Dr Jane Kinnaird (April-July, 2014), working in the lab of Prof Brian Shiels,
Glasgow University, UK
Dr Fiona Kenyon (May 2001 to Oct. 2004), Edinburgh University, UK
“ Currently, Research Associate, Moredun Research Institute, Scotland”
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Dr Davis Nwakanma (Jan 2001 to Oct. 2004), Edinburgh University, UK
“Currently, Principle investigator, Medical Research Council Unit, The
Gambia”
C5. SERVICES:
1. Expert Advisor.
International Atomic Energy Agency.
External reviewer of a research project entitled “Isotopes for control of human
communicable diseases”. The project runs in 9 African countries and aims to validate
the use of molecular diagnosis of drug resistance of Plasmodium falciparum malaria
infection. My role involve conducting lectures on molecular basis of drug resistance
and establishing laboratory techniques for typing alleles of drug resistance genes in
natural P. falciparum infection.
Between 1999 and 2002 I undertook consultancy missions to many countries including
Sudan, Kenya, Mali and Thailand, Cameroon, to evaluate and help with
implementation of the above project.
World Health Organization, Medicine for Malaria Venture:
Consultation meeting on methods and techniques for clinical trials on antimalarial
drug efficacy, 29-31 May 2007, Amsterdam, the Netherlands
2. Academic Reviews.
I am a regular reviewer for major journals in tropical medicine and parasitology,
including:
Journal of Infectious Diseases
Antimicrobial and Chemotherapy
International Journal for Parasitology
Infection Genetics and Evolution
PLOS ONE
Transactions of the Royal Society of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene
Acta Tropica
Tropical Medicine and International Health
Parasitology Today currently “Trends in Parasitology”
Parasitology
Journal of Parasitology
(ii) Grant Reviewing:
I have acted as reviewer for project grants for the following funding organizations
The Institut Pasteur, France
Wellcome Trust, UK
Medical Research Council, UK
Netherlands Foundation for the Advancement of Tropical Research
(WOTRO), The Netherland.
Swiss National Science Foundation, Switzerland
Royal Veterinary College, University of London, UK, Internal grant scheme
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Sultan Qaboos University Research fund, Oman.
3. Editorial services
Guest Editor, Acta Tropica, Special Issue “Drug resistance in malaria: It
population biology and implications for control”, Volume 94, June 2005
4. University Committees
College committees
Chair, Undergraduate Research Management Committee, 2010- present
Member, Curriculum Committee, 2014 to present
Member, Research and Ethics Committee (2006-2012)
Member, Postgraduate students and Training Committee (2010-2012)
Department committees
Department of Biochemistry Promotion Committee (Chair), 2015
Department of genetics Promotion Committee, (2015)
Department of Physiology Promotion Committee (2015)
Department of Ophthalmology Promotion Committee (2015)
Department of Biochemistry Recruitment Committee (2010-2012)
Department of Biochemistry Postgraduate Committee (Chair) (2009-2011)
Department of Biochemistry Promotion Committee (2010-2013)
Department of Biochemistry Research Committee (Chair) (2013-present)
5. National committees
Member of Oman Animal and plant genetic resources centre scientific committee,
(2013-present)
6. Community services.
Since 2006, I have been working with the National Malaria Control
Department, Ministry of Health, and Oman, to establish advanced molecular
facilities for diagnosis of imported malaria parasites. Since 2006, I acquired
three research grants, one supported by SQU and two by the International
Atomic Energy Agency (IAEA) aim at using radionuclide-based molecular
methods for diagnosis of different species of malaria parasites. This has
allowed training of staff in the malaria control department on molecular
diagnosis, and establishment of PCR-Based diagnostic facilities.
In addition, I have recently acquired a project grant from Research Council,
Oman to work on Theileria parasites. The project is carried in close
collaboration with scientists in the Ministry of Agriculture and Fisheries. This
project will contribute to building capacity for Theileria control program, and
strengthen the national research capacity and skills for diagnosis of parasitic
diseases in Animals. Two staff members of Ministry of Agriculture and
Fisheries are involved as graduate students in the project.
Organized public lectures to staff of Ministry of Health, Sudan, to raise
awareness of rational use of antimalarial, 1999 & 2000
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7. Professional Affiliations
a) British Society for Parasitology
b) The Royal Society of Tropical Medicine and Hygiene, UK
c) The American Society of Tropical Medicine and Hygiene, USA
d) Sudanese Society of Tropical Medicine and Hygiene
C6. SCHOLARLY ACHIEVEMENTS.
Research interests:-
My research interest is in the field of molecular and population genetics of infectious
diseases. I have applied my expertise and knowledge to analysis of the human malaria
parasite Plasmodium falciparum. This includes work on genetic polymorphism within
populations of the parasite and its population genetic structure. This is especially in
relation to evolution of drug resistance, and how environmental and parasite genetic
factors influence the transmission of resistant parasites. I have recently initiated
parallel work on population genetics of Mycobacterium tuberculosis and Theileria sp.
Research grants
1. Co- principal Investigator. Imported malaria transmission-free setting:
importance of detection and characterisation of imported parasites. The
Swedish Foundation for International Cooperation in Research and Higher
Educating (STINT), 2019 to 2020 US10000
2. Principal investigator. Sexual stage specific protein genes of Theileria
lestoquardi: putative target for transmission blocking intervention and marker for
transmission dynamics. Gulf Cooperation Countries (GCC) Research Program
2017 to 2020 US150000
3. Principal investigator. Use of radionuclide-based molecular methods for
detection of drug resistant malaria in Oman Technical Cooperation programme,
International Atomic Energy Agency, Austria Oct 2016 to Oct 2017 US200:000
4. Faculty Mentored Undergraduate Research Award Program ( FURAP ).
Evaluation of malaria Loop mediated isothermal amplification (LAMP) assay for
malaria diagnosis in asymptomatic carriers in Oman.The Research Council, Oman
Sep 2014 to June 2015 RO 2400
5. Co-principal Investigator. PI: Yasmin El Tahir. A Novel molecular approach to
investigating Brucellosis His Majesty’s grant, Sultan Qaboos University, Oman.
May 2014-June 2017
6. Principal investigator. Use of radionuclide-based molecular methods for
detection of imported malaria in Oman. Technical Cooperation programme,
International Atomic Energy Agency, Austria Oct 2014 to Oct 2016 US300:000
7. Principal investigator. Theileria in Oman: molecular epidemiology and disease.
The Research Council, OmanSep 2013 to Sep 2016 RO 193,200
8. Faculty Mentored Undergraduate Research Award Program ( FURAP).
Transmission dynamics of Mycobacterium tuberculosis in Oman. The Research
Council, Oman Sep 2013 RO 2400
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9. Co-principal Investigator. Transmission dynamics and spread of drug resistance
of Mycobacterium tuberculosis in Oman. Sultan Qaboos University, Oman. Dec
2012 to Dec 2014 OR 16.000
10. Principal investigator. Radionuclide based methods for monitoring imported
malaria into Oman.
11. Principal investigator. Technical Cooperation programme, International Atomic
Energy Agency, Austria. Jan 2012 to Dec. 2013 US500:000
12. Co- investigator Evolution of parasite reproductive strategy in the wild
Natural Environment Research Council (NERC), UK. Sep 2011 to May 2012
£60,000
13. Co-investigator. Population genetics of malaria parasites in relation to
geographical, transmission intensities. Swedish International Development
Cooperation Agency (SIDA), Sweden Jan 2010 to June 2013
SK1500,000
14. Co-investigator. Characterization, Evaluation and Conservation of Indigenous
Animal Genetic Resources in the Sultanate of Oman. Sultan Qaboos University,
Oman .May 2008 to May 2011 OR 79,000
15. Principal investigator. The brunt of mutations conferring drug resistance on the
fitness of malaria parasites. Sultan Qaboos University, Oman. 2008 to Dec. 2011
OR 18,500
16. Co- investigator. Genetic polymorphisms of nutrient and inflammatory Genes in
diffused large B cell lymphoma in Omani Arabs. Sultan Qaboos University, Oman.
June 2008 to June 2009 OR 1,800
17. Principal investigator. Molecular surveillance and genetic studies of endogenous
and imported malaria in Oman. Sultan Qaboos University, project grant. 2005 to
Dec 2008 OR 24,500
18. Co-investigator Evolution of drug resistant Plasmodium falciparum parasite in
eastern Sudan. Swedish International Development Cooperation Agency
(SIDA) Nov 2006 to Nov 2007. SK70,000
19. Principal investigator. (this project has been approved but not awarded)
Impact of environmental and parasite genetic factors on of Plasmodium
falciparum gametocytogenesis.BiamalPar & MIM/TDR Re-integration grant Aug
2007 to Oct 2009 EURO 370.000
20. Principal investigator. Dynamics of gametocyte production of Plasmodium
falciparum in nature. Medical Research Council, UK. Jan 2001 to 2004
£400,000
21. Principal investigator. Population genetics of Plasmodium falciparum in a village
in Sudan. Wellcome Trust Oct 1993 for 3 years £37,000
22. Supervisor. Impact of anti-malarial drugs on transmission of the human malaria
parasite Plasmodium falciparum. International Atomic Energy Agency (IAEA)
February 2002- March 2003 $ 20,000
23. Principal investigator Development of allele specific probes for detection of
drug resistance genes in Plasmodium falciparum. International Atomic Energy
Agency, Austria June 2000-June 2001 $3000
24. Principal investigator. Gametocyte production by Plasmodium falciparum clones.
Wellcome Trust, UK .Oct 1998 for 18 months. £68,282.
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25. Co-investigator. Strengthening research capacity for malaria in Sudan.
WHO/MIM, Swaziland. July 1998. $10,000
26. Supervisor .Spatial structure of Plasmodium falciparum in villages in eastern
Sudan. WHO/TDR. March 1999 to March 2000 $18,000
27. Supervisor. Plasmodium falciparum gametocyte persistence and dynamics in an
area of unstable malaria in eastern Sudan. WHO/TDR. March 1998 to March 1999
$18,000
28. Co-investigator. The effect of P. falciparum strain variation on clinical
presentation and immune status of malaria patients. WHO1990-1992
$120,000
Peer-reviewed publications
1. Petra Schneider P, Babiker HA, Gadalla A, and Reece SE (2019). Evolutionary
sex allocation theory explains sex ratios in natural Plasmodium falciparum
infections. Int J Parasitol (in press).
2. Amani M.A Bakhiet AM, Abdelraheem MH, Kheir A, Omer S, Gasmeseed L,
Abdel-Muhsin.A, Naiem A, Ahmed Al Hosni a, Al Dhuhli A, Al Rubkhi M, Al-
Hamidhi S, Gadalla A, Mukhtar M, Sultan A, Babiker HA (2019) Evolution of P.
falciparum drug resistance genes following artemisinin combination therapy (ACT)
in Sudan. Trans. Roy. Soc. Trop. Med. Hyg (in press)
3. Abdelraheem MH, Bansal D, Idris MA, Mukhtar MM, Hamid MMA, Imam ZS,
Getachew S, Sehgal R, Kaur H, Gadalla AH, Al-Hamidhi S, Al-Hashami Z, Al-
Jabri A, Sultan AA, Babiker HA (2018) Genetic diversity and transmissibility of
imported Plasmodium vivax in Qatar and three countries of origin. Sci Rep.
11;8(1):8870
4. Awad H, Al-Hamidhi S, El Hussein AM, Yousif YMZ, Taha KM, Salih DA,
Weir W, Babiker HA (2018) Theileria lestoquardi in Sudan is highly diverse and
genetically distinct from that in Oman. Infect Genet Evol. 62:46-52.
5. Bansal D, Acharya A, Bharti PK, Abdelraheem MH, Elmalik A, Abosalah S,
Khan FY, ElKhalifa M, Kaur H, Mohapatra PK, Sehgal R, Idris MA, Mahanta J,
Singh N, Babiker HA, Sultan AA (2017). Distribution of Mutations Associated
with Antifolate and Chloroquine Resistance among Imported Plasmodium vivax in
the State of Qatar.Am J Trop Med Hyg. 97(6):1797-1803.
6. Al-Fahdi A, Alqamashoui B, Al-Hamidhi S, Kose O, Tageldin MH, Bobade P,
Johnson EH, Hussain AR, Karagenc T, Tait A, Shiels B, Bilgic HB, Babiker H
(2017). Molecular surveillance of Theileria parasites of livestock in Oman.Ticks
Tick Borne Dis. 8(5):741-748.
7. Gadalla AA, Schneider P, Churcher TS, Nassir E, Abdel-Muhsin AA, Ranford-
Cartwright LC, Reece SE, Babiker HA (2016) Associations between Season and
Gametocyte Dynamics in Chronic Plasmodium falciparum Infections. PLoS One.
2016 Nov 21;11(11):e0166699.
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8. Al-Hamidhi S, Weir W, Kinnaird J, Tageledin M, Beja-Pereira A, Morrison I,
Thompson J, Tait A, Shiels B, Babiker HA. Theileria lestoquardi displays reduced
genetic diversity relative to sympatric Theileria annulata in Oman. Infect Genet
Evol. 2016 Sep;43:297-306
9. Al-Hamidhi S, H Tageldin M, Weir W, Al-Fahdi A, Johnson EH, Bobade P,
Alqamashoui B, Beja-Pereira A, Thompson J, Kinnaird J, Shiels B, Tait A,
Babiker H. (2015) Genetic diversity and population structure of Theileria annulata
in Oman. PLoS One. 2015 Oct 15;10(10):e0139581
10. Bakhiet AM, Abdel-Muhsin AM, Elzaki SE, Al-Hashami Z, Albarwani HS,
AlQamashoui BA, Al-Hamidhi S, Idris MA, Elagib AA, Beja-Pereira A, Babiker
HA (2015).The effect of a decade of artemisinin-based combination therapy and
intense control measures on Plasmodium falciparum population genetic structure in
Sudan. Acta Tropica, 148:97-104
11. Schneider P, Reece SE, van Schaijk BC, Meaden CS, Ranford-Cartwright L,
Gadalla A and Babiker HA (2015) Quantification of male and female Plasmodium
falciparum gametocytes by real-time PCR. Mol Biochem Parasitol, 199(1-2), 29-33
12. Lazaridis I, Patterson N, Mittnik A, Renaud G, Mallick S, Kirsanow K,
Sudmant PH, Schraiber JG, Castellano S, Lipson M, Berger B, Economou C,
Bollongino R, Fu Q, Bos KI, Nordenfelt S, Li H, de Filippo C, Prüfer K, Sawyer S,
Posth C, Haak W, Hallgren F, Fornander E, Rohland N, Delsate D, Francken M,
Guinet JM, Wahl J, Ayodo G, Babiker HA, Bailliet G, Balanovska E, Balanovsky
O, Barrantes R, Bedoya G, Ben-Ami H, Bene J, Berrada F, Bravi CM, Brisighelli F,
Busby GB, Cali F, Churnosov M, Cole DE, Corach D, Damba L, van Driem G,
Dryomov S, Dugoujon JM, Fedorova SA, Gallego Romero I, Gubina M, Hammer
M, Henn BM, Hervig T, Hodoglugil U, Jha AR, Karachanak-Yankova S,
Khusainova R, Khusnutdinova E, Kittles R, Kivisild T, Klitz W, Kučinskas V,
Kushniarevich A, Laredj L, Litvinov S, Loukidis T, Mahley RW, Melegh B,
Metspalu E, Molina J, Mountain J, Näkkäläjärvi K, Nesheva D, Nyambo T,
Osipova L, Parik J, Platonov F, Posukh O, Romano V, Rothhammer F, Rudan I,
Ruizbakiev R, Sahakyan H, Sajantila A, Salas A, Starikovskaya EB, Tarekegn A,
Toncheva D, Turdikulova S, Uktveryte I, Utevska O, Vasquez R, Villena M,
Voevoda M, Winkler CA, Yepiskoposyan L, Zalloua P, Zemunik T, Cooper A,
Capelli C, Thomas MG, Ruiz-Linares A, Tishkoff SA, Singh L, Thangaraj K,
Villems R, Comas D, Sukernik R, Metspalu M, Meyer M, Eichler EE, Burger J,
Slatkin M, Pääbo S, Kelso J, Reich D, Krause J (2014). Ancient human genomes
suggest three ancestral populations for present-day Europeans. Nature, 513, 409-
413
13. Al-Hamidhi S, Mahdy MA, Idris MA, Bin Dajem SM, Al-Sheikh AA, Al-
Qahtani A, Al-Hashami Z, Al-Farsi H, Al-Mekhlafi AM, Saif-Ali R, Beja-Pereira
A, Babiker HA* (2014). The prospect of malaria elimination in the Arabian
Peninsula: A population genetic approach. Infect Genet Evol. 27C:25-31
14. Tamimi Y, Al-Harthy S, Al-Haddabi I, Al-Kindi M, Babiker H, Al-Moundhri
M, Burney I (2014). The p53 Mutation/Deletion Profile in a Small Cohort of the
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Omani Population with Diffuse Large B-Cell Lymphoma. Sultan Qaboos Univ Med
J. 14(1):e50-8.
15. Al-Hamidhi S, Mahdy MA, Al-Hashami Z, Al-Farsi H, Al-Mekhlafi AM, Idris
MA, Beja-Pereira A, Babiker HA* (2013).Genetic diversity of Plasmodium
falciparum and distribution of drug resistance haplotypes in Yemen. Malar J. 2013,
15;12(1):244
16. Babiker HA*, Gadalla AA, Ranford-Cartwright L (2013). The role of
asymptomatic P. falciparum parasitaemia in the evolution of antimalarial drug
resistance in areas of seasonal transmission. Drug Resist Updat;16(1-2):1-9
17. Al-Kharusi N, Babiker HA, Al-Salam S, Waly MI, Nemmar A, Al-Lawati I,
Yasin J, Beegam S, Ali BH (2013) Ellagic acid protects against cisplatin-induced
nephrotoxicity in rats: a dose-dependent study. Eur Rev Med Pharmacol Sci,
17(3):299-310.
18. Mahgoub O, Babiker HA, Kadim IT, Al-Kindi M, Hassan S, Al-Marzooqi W,
Eltahir YE, Al-Abri MA, Al-Khayat A, Al-Sinani KR, Hilal Al-Khanjari H, Costa
V, Chen S, Beja-Pereira A (2013). Disclosing the origin and diversity of Omani
cattle. Animal Genetics. 44(3):336-9.
19. Al-Farsi HM, Al-Hasham ZS, Bin Dajem SM, Al-Sheikh AH, Al-Qahtani A ,
Beja-Pereira A, Idris MA, Babiker HA* (2012) Source of drug resistant
Plasmodium falciparum in a potential malaria elimination site in Saudi Arabia.
Infection, Genetics and Evolution 12, 1253–1259.
20. Bin Dajem S.M, Al-Farsi H.M, Al-Hashami Z.S, Al-Sheikh A.A, Al-Qahtani
A, Babiker H.A* (2012). Distribution of drug resistance genotypes in Plasmodium
falciparum in an area of limited parasite diversity in Saudi Arabia. Am. J. Trop.
Med. Hyg 86(5), 782–788
21. Sutherland C., Babiker, H.A., Mackinnon, M.J. Ranford-Cartwright, L., El
Sayed, B. (2011) Rational deployment of antimalarial drugs in Africa: should first-
line combination drugs be reserved for paediatric malaria cases? Parasitology
138(12):1459-68
22. Babiker H.A* (2011) The role of crossing and recombination in dissemination
of drug resistance in Plamodium falciparum: filed observation. Revista CENIC.
Lencias Biologicas, Vol 41, INF001 (ISSN:0253-5688)
23. Reece S, Ali E, Schneider P and Babiker HA (2010). Stress, drugs and
evolution of reproductive restraint in malaria parasites. Proc Roy Soc Lond B
22;277(1697):3123-9.
24. Kheir A., Nwakanma, D., Akbarov, Y., Al-Saai, S., Al-Gazali, A., Swedberg,
G., Babiker HA* (2010). Transmission and cross-mating of high-level resistance
Plasmodium falciparum dhfr haplotypes in the Gambia. Am. J. Trop. Med. Hyg. 82,
535-541.
17
25. Burney IA, Al Sawai BS, Dawood AA, Babiker H, Al Moundhri MS. (2009)
Association of polymorphisms in cytokine genes with Diffuse Large B cell
lymphoma and its outcomes in Omani Arabs. Eur J Cancer 7: 566, (abs9222)
26. Babiker HA* (2009) Seasonal fluctuation of drug resistant malaria parasites: a
sign of fitness cost. Trends Parasitol, 25(8), 351-352.
27. Babiker HA*., Hastings IM, Svedberg G (2009) Impaired fitness of drug-
resistant malaria parasites: evidence and implication on drug deployment policies.
Expert Review of Anti-infective Therapy, 7(5), 581-593.
28. Al-Saai, S., Kheir, A., Abdel-Muhsin A, Al-Ghazali, A., Nwakanma, D.,
Swedberg, G., Babiker H.A* (2009) Distinct haplotypes of dhfr and dhps among
Plasmodium falciparum isolates in an area of high level of sulfadoxine-
pyrimethamine (SP) resistance in eastern Sudan. Infection, Genetics and Evolution
9, 778–783.
29. Babiker, H.A*., Schneider, P., Reece S.E. (2008) Gametocytes: Insights
gained during a decade of molecular monitoring. Trends Parasitol, 24(11), 525-
530.
30. Babiker H.A*. and Schneider P (2008) Application of reverse transcription
PCR (RT-PCR) for monitoring transmission stages of mlaria parasites. IOP
Biochemical Material. 3, 034007(12pp).
31. Nwakanma, D., Kheir, A., Sowa, M., Dunyo, S., Jawara, M., Pinder, M.,
Milligan, P., Walliker, D., Babiker H.A* (2008) High gametocyte complexity and
mosquito infectivity of Plasmodium falciparum in The Gambia. Int J Parasitol 38,
219-227.
32. El-Sayed B., El-Zaki S., Babiker H.A, Gadalla N, Ageep T, Mansour F,
Baraka O, Milligan P, Babiker A (2007) A Randomized Open-Label Trial of
Artesunate-Sulfadoxine-Pyrimethamine with or without Primaquine for Elimination
of Sub- Microscopic P. falciparum Parasitaemia and Gametocyte Carriage in
Eastern Sudan. PLoS Clin Trials 12: e1311.
33. Tanabe K, Sakihama N, Walliker D, Babiker H.A, Abdel-Muhsin AM,
Bakote'e B, Ohmae H, Arisue N, Horii T, Rooth I, Farnert A, Bjorkman A,
Ranford-Cartwright L. (2007) Allelic dimorphism-associated restriction of
recombination in Plasmodium falciparum msp1. Gene. 397, 153-60
34. A-Elbasit E.E, ElGhazali, G., A-Elgadir, T.M.E., Hamad, A., Babiker H.A.,
El-Bashir M.I., Giha, H.A. (2007) Allelic polymorphism of MSP2 gene in severe P.
falciparum malaria in an area of low and seasonal transmission. Parasitol. Res.
102(1):29-34.
35. Ali, E., Mackinnon, M., Abdel-Muhsin A, Ahmed, S., Walliker, D., Babiker,
H.A.* (2006) Increased density but not prevalence of gametocytes following drug
treatment of Plasmodium falciparum. Trans. Roy. Soc. Trop. Med. Hyg. 100, 176-
183.
18
36. Wargo, A.R, Randle, N., Chan, B., Thompson, J., Read, A.F., Babiker. H.A.
(2006) Plasmodium chabaudi: reverse transcription PCR (RT-PCR) for the
detection and quantification of transmission stage malaria parasites. Exp Parasitol.
112, 13-20.
37. Giha, H., Elbashir, M.I, A-Elbasit, I.E, A-Elgadir, T.M, ElGhazali, G.,
Mackinnon, M.J., Babiker, H.A (2006) Drug resistance-virulence relationship in
Plasmodium falciparum causing severe malaria in an area of seasonal and unstable
transmission. Acta Tropica. 97, 181-7.
38. Paganotti, G.M, Palladino, C., Modiano, D., Sirima, B.S, Råberg, L., Diarra,
A., Konaté, A., Coluzzi, M., Walliker D. and Babiker H.A* (2006) Genetic
complexity and gametocyte production of Plasmodium falciparum in Fulani and
Mossi communities in Burkina Faso. Parasitology 132, 607-14.
39. Ferguson, H.M, Gouagna L.C., Obare, P., Read, A.F., Babiker, H.A., Githure,
J., Beier, J.C. (2005) The presence of Plasmodium falciparum in human blood
increases the gravidity of Anopheles gambiae mosquitoes. Am. J. Trop. Med. Hyg.
73, 312-320.
40. Nassir E, Abdel-Muhsin AM, Suliaman S, Kenyon F, Kheir A, Geha H,
Ferguson HM, Walliker D, Babiker H.A* (2005) Impact of genetic complexity on
longevity and gametocytogenesis of Plasmodium falciparum during the dry and
transmission-free season of eastern Sudan. Int J Parasitol. 35, 49-55.
41. Walliker, D., Hunt, P., Babiker H.A* (2005) Fitness of drug-resistant malaria
parasites. Acta Tropica 94, 251-259.
42. Babiker, H.A.*, Satti, G., Ferguson, H.M., Bayoumi, R., Walliker, D. (2005)
Drug resistant Plasmodium falciparum in an area of seasonal transmission. Acta
Tropica 94, 260-268.
43. Babiker H.A*. and Mackinnon M (2005) Drug resistance in malaria: its
population biology and implications for control. Acta Tropica, 94, 161-162.
44. Adam, M.E., A/Karim, E.I., Elkadaru, A.Y., Ibrahim, K.E.E., Berger, B.J.,
Wise, M., Babiker, H.A.* (2004) Imipramine induced complete reversal of
chloroquine resistance in Plasmodium falcipareum infections in Sudan. Saud
Pharmaceut J. 12, 130-35.
45. Abdel-Muhsin A. A, Mackinnon, M., Ali, E., Nassir, E. Suleiman, S., Ahmed,
S., Walliker, D. & Babiker, H.A.* (2004) Evolution of drug resistance genes in
Plasmodium falciparum in an area of seasonal transmission in eastern Sudan:
implication for control. J Infect Dis. 189, 1239-1244.
46. Paganotti G., Babiker H.A, Modiano D., Sirima BS, Verra F, Konate A,
Ouédraogo AL, Amidou Diarra A, Mackinnon MJ, Coluzzi M, and Walliker D
(2004) Genetic Complexity of Plasmodium falciparum in two ethnic groups of
19
Burkina Faso (West Africa) with marked differences in susceptibility to malaria.
Am. J. Trop. Med. Hyg. 71, 173-178.
47. Abdel-Muhsin A., Mackinnon, M., Awadalla, P., Ali, E., Suleiman, S.,
Ahmed, S., Walliker, D., Babiker, H.A.* (2003) Local differentiation in
Plasmodium falciparum drug resistance genes in Sudan. Parasitology 126, 391-
400.
48. Magesa SM, Mdira KY, Babiker HA, Alifrangis M, Farnert A, Simonsen PE,
Bygbjerg IC, Walliker D, Jakobsen PH (2002) Diversity of Plasmodium falciparum
clones infecting children living in a holoendemic area in north-eastern Tanzania.
Acta Tropica, 84, 83-92
49. Hamad A, Nugud AD, Arnot D, Abdel-Muhsin AA, Giha H, Satti G, Theander
T, Creasey A, Babiker H.A, Elnaiem D (2002) Marked seasonality of malaria
transmission in two rural sites in eastern Sudan. Acta Tropica 83, 71-82.
50. Adbel-Muhsin, A.A., Ranford-Cartwright, L.C., Khan, B., Medane, A., Salah
Ahmed Suad Suleiman; Paul Hunt; Walliker, D. & Babiker, H.A.* (2002)
Detection of mutations in Plasmodium falciparum dihydrofolate reductase (dhfr) by
dot-blot hybridisation. Am. J. Trop. Med. Hyg. 67, 24-27.
51. Ranford-Cartwright, L.C, Johnston, K, Abdel-Muhsin, A., Khan, B, &
Babiker H.A (2002) Critical comparison of molecular genotyping methods for
detection of drug resistant Plasmodium falciparum. Trans. Roy. Soc. Trop. Med.
Hyg . 96, 568-72.
52. Abdel-Wahab A, Abdel-Muhsin A, Ali E, Suleiman S, Ahmed S, Walliker D.
& Babiker H.A* (2002) Dynamics of gametocytes among Plasmodium falciparum
clones in natural infections in an area of highly seasonal transmission. J Infect
Dis.185, 1838-42.
53. Rowe A.J, Kyes S.A., Rogerson S.J., Babiker H.A and Ahmed Raza (2002)
Identification of a conserved Plasmodium falciparum var gene implicated in
malaria in pregnancy. J Infect Dis.185, 1207-1211.
54. Babiker H.A* & Walliker, D (2002) Is Plasmodium falciparum chloroquine
resistance a multi-locus phenotype? J Infect Dis. 185, 406-7.
55. Elkheir, H., Elkarim, E.I, Eltayeb, I.B., Elkadaru, A.E., Babiker, H.A. and
Ibrahim, A.M. (2001) Efficacy of Sulphadoxine and pyrimethamine in the treatment
of chloroquine resistant falciparum malaria. Saud.i Med. J. 22, 690-693.
56. Awadalla P, Walliker D, Babiker H.A & Mackinnon M (2001) The Question
of Plasmodium falciparum Population Structure. Trends Parasitol. 17, 351-353.
57. Binks , R.H, Baum , J., Oduola , A.M.J., Arnot , D.E., Babiker , H.A.,
Kremsner , P.G., Roper , C., Greenwood , B.M., Conway D.J. (2001) Population
genetic analysis of the Plasmodium falciparum erythrocyte binding antigen-17 (eba-
175) gene. Mol Biochem Parasitol. 114, 63-70
20
58. Farnert A, Arez AP, Babiker H.A, Beck HP , Benito A , Björkman A, Bruce
M, Conway D, Day K, Mercereau-Puijalon O, Ranford-Cartwright LC, do Rosário
VE, Rubio J, Snounou G, Walliker D, Zwetyenga J.(2001) Genotyping of
Plasmodium falciparum infections: A comparative multi-centre study. Trans. Roy.
Soc. Trop. Med. Hyg. 95, 225-232.
59. Babiker H.A*, S. Pringle, A. Abdel-Muhsin, M Mackinnon, P. Hunt & D.
Walliker (2001) High level chloroquine resistance in Plasmodium falciparum is
associated with mutations in the chloroquine resistance transporter gene Pfcrt and
the multi-drug resistance gene Pfmdr1. J. Infect Dis, 183, 1535-8.
60. Menegon, M., Severini, C., Sannella, A., Paglia, M.G., Abdel-Wahab, A.,
Abdel-Muhsin A., Babiker, H.A., Walliker, D. and Alano, P. (2000) Genotyping of
Plasmodium falciparum gametocytes by RT-PCR. Mol Biochem Parasitol, 111,
153-161.
61. Babiker H. A*., Abdel-Muhsin A.A, Hamad, A., Mackinnon, M., Hill, W.G.
& Walliker, D (2000) Population dynamics of Plasmodium falciparum in an
unstable malaria area of eastern Sudan. Parasitology. 120, 105-111.
62. Babiker H.A*., Abdel-Wahab A.O, Ahmed S., Suleiman S., Ranford-
Cartwright, L, Carter R. & Walliker, D (1999) Detection of low level Plasmodium
falciparum gametocytes using reverse transcriptase polymerase chain reaction (RT-
PCR). Mol. Biochem Parasitol. 99, 143-148.
63. Babiker H. A*., Ranford-Cartwright, L. & Walliker, D (1999) Genetic
structure and dynamics of Plasmodium falciparum infection in the Kilombero
region in Tanzania. Trans. Roy. Soc. Trop. Med. Hyg. 93(suppl) S1/11-S1/14.
64. Babiker H. A. (1998) Unstable malaria: the influence of the dry season:
Plasmodium falciparum population in the unstable malaria area in eastern Sudan:
Stable and genetically complex. Trans. Roy. Soc. Trop. Med. Hyg. 92, 585-589
65. Babiker H. A*., Abdel-Muhsin A.A, Ranford-Cartwright, L, Satti, G. &
Walliker, D (1998) Characteristics of Plasmodium falciparum parasites that
survive the lengthy dry season in eastern Sudan where malaria transmission is
markedly seasonal. Am J Trop Med Hyg. 59, 582-590.
66. Ranford-Cartwright, L., Taylor, J., Umasunthar, T. Taylor, L.H, N., Babiker,
H. A., Lell, B., Schmidt-Ott, J.R. Lehman, L.G., Walliker, D., Kremsner, P.G.
(1997) Molecular analysis of recrudescent parasites in a Plasmodium falciparum
drug efficacy trial in Gabon. . Trans. Roy. Soc. Trop. Med. Hyg. 91, 719-724.
67. Babiker, H.A*.and Walliker, D. (1997) Current views on the population
genetic structure of Plasmodium falciparum: implications for control. Parasitology
Today 13, 262-267.
68. Babiker, H.A*., Lines, J., Hill, W.G. and Walliker, D. (1997) Population
structure of Plasmodium falciparum in villages with different malaria endemicity in
21
east Africa. Am J Trop Med Hyg 56, 141-147.
69. Ranford-Cartwright, L., Taylor, R., Asgri-Jirhandeh, N., Smith, D. B., Roberts,
P. E., Robinson, J., Babiker, H. A., Riley, E. M., Walliker, D., & McBride J.
(1996) Differential antibody recognition of FC27-like Plasmodium falciparum
merozoite surface protein MSP2 antigens which lack 12 amino acid repeats.
Parasit. Immunol. 18, 411-420.
70. Roper, C., Elhassan, I. M., Hviid, L., Giha, H., Richardson, W., Babiker, H.A,
Satti, G., Theander, T., Arnot, D. (1996) Detection of very low level Plasmodium
falciparum infection using nested polymerase chain reaction, and assessment of the
epidemiology of unstable malaria in Sudan. Am. J. Trop. Med. Hyg. 54, 325-331.
71. Hill, G.W, & Babiker, H.A. (1995) Estimation of numbers of malaria clones
in blood samples. Proc Roy Soc Lond B 262, 249-257.
72. Babiker, H.A., Charlwood, D., Smith T. and Walliker, D.(1995) Gene flow
and cross-mating in Plasmodium falciparum in households in a Tanzanian village.
Parasitology . 111, 433-442.
73. Roper, C., Elhassan, I.M., Sultan, A., A., Satti, G, Babiker, H.A. & Arnot,
D.E. (1995) Malaria transmission and R0 value question. A PCR based approach.
Sud Med J. 33, 33-39.
74. Babiker, H.A*., Bayoumi, R. and Walliker D. (1995) Genetic diversity of
Plasmodium falciparum in Sudan: implications for control. Sud Med J. 33, 67-79.
75. Babiker, H.A*., Satti, G. and Walliker, D. (1995) Genetic changes in the
population of Plasmodium falciparum population in a Sudanese village over three
year period. Am J Trop Med Hyg 53, 7-15.
76. Hill, G.W, Babiker, H.A., Randford-Cartwright, L. and Walliker, D. (1995)
Estimation of inbreeding coefficient from genotypic data on multiple alleles, and
application to estimation of clonality in malaria parasites. Genet Res. 65: 53-61.
77. Bayoumi, R.A., Babiker, H.A. & Arnot, D.E. (1994) Uptake and efflux of
chloroquine by chloroquine-resistant Plasmodium falciparum clones recently
isolated in Africa. Acta Tropica.58, 141-149.
78. Babiker, H.A., Ranford-Cartwright, L., Currie, D., Charlwood, D.,
Billingsley, P., Teuscher, T., Walliker, D. (1994) Random mating in natural
populations of the malaria parasite Plasmodium falciparum. Parasitology 109,
413-421.
79. Babiker, H.A*., Randford-Cartwright, L., Sultan, A., Satti, G. and Walliker,
D. (1994) Genetic evidence for the occurrence of R1 chloroquine resistant
Plasmodium falciparum parasites in patients with relapses of clinical malaria, in a
village in Sudan. Trans. Roy. Soc. Trop. Med. Hyg. 88, 328-331.
80. Bayoumi, R.A., Creasey, A.M., Babiker, H.A., Carlton, J., Sultan, A., Satti,
22
G., Sohal, A., Walliker, D. & Arnot, D.E. (1993) Drug response and genetic
characterisation of Plasmodium.falciparum clones recently isolated from a
Sudanese village. Trans. Roy. Soc. Trop. Med. Hyg. 87, 454-458.
81. Babiker, H.A*. and Ranford-Cartwright, L. (1993) Diversity of two antigen
genes of malaria parasite detected by PCR and ECL3'-oligolabelling system. ECL
Highlights. S550/6505/93/1
82. Foley, M. Ranford-Cartwright, L. C. and Babiker, H.A. (1992) Rapid and
simple method for isolating malaria DNA from fingerprick samples of blood. Mol.
Biochem. Parasitol. 53, 241-244.
83. Babiker, H.A*., Creasey, A.M., Bayoumi, R.A., Walliker, D. & Arnot, D.E.
(1991). Genetic diversity of the human malaria parasite Plasmodium falciparum in
a village in Eastern Sudan. II. Drug resistance, molecular karyotypes and the mdr-1
genotype in recent field isolates. Trans. Roy. Soc. Trop. Med. Hyg. 85, 578-583.
84. Babiker, H.A*., Creasey, A.M., Fenton, B., Bayoumi, R.A., Arnot, D.E &
Walliker, D. (1991). Genetic diversity of the human malaria parasite Plasmodium
falciparum in a village in Eastern Sudan. I . Diversity in enzymes, 2D-PAGE
proteins and antigens. Trans. Roy. Soc. Trop. Med. Hyg. 85, 572-577.
85. Bayoumi, R.A., Babiker, H.A., Ibrahim, S.M., Galib, H.W., Saeed, B.O.,
Khider, S. & Karim, E.A. (1989). Spread of chloroquine resistant Plasmodium
falciparum in Sudan. Acta Tropica 46, 157-165.
Research Published in Proceedings of Scientific Meetings.
86. Walliker, D., Ranford-Cartwright, L. C. & Babiker, H.A.(1993) Genetic
recombination in field populations of Plasmodium falciparum. In "Genome analysis
of protozoan parasites" (ed) Morzaria, S.P. Proceedings of a workshop held at Ilrad
Nirobi, Kenya, 11-13th November 1992.
Book review
87. Babiker H.A (2003) Book review “PCR Mutation Detection Protocols, ed.
Dimal M. Theophilus and Ralph Rapley, Human Press”, Mol Biotech 24, 309.
88. Babiker H. A (1999) Malaria in the Solomon Islands “book review”.
Parasitology Today 15, 349.
Book Chapter
1. Walliker D., Babiker, H.A., Ranford-Cartwright L. “The genetic structure of
malaria parasite populations” in Malaria: Parasite biology, pathogenesis and
protection” I. W. Sherman (ed). American Society for Microbiology.
Technical Reports:
Standard Operating Procedures for Regional Project 6025, Detection of drug-resistant
malaria.Compiler/editor Lisa Ranford-Cartwright and Hamza Babiker. International
Atomic Energy Agency, Vienna July 2003. (Available in print or CD format)
23
Contribution in scientific meetings
Invited speaker.
Malaria elimination in the GCC countries, impact of imported malaria. 5th Science
and Technology Exchange Program (STEP)meeting Karachi., Pakistan, 27 Feb to
2nd March 2019.
The prospect of malaria elimination in the Arabian Peninsula: a population
genetic approach. The Middle East and South Asia Conference on
Epigenetics and Genomics of Infectious Diseases” in Amman, Jordan, 7-9th March
2016.
The role of cross-mating in evolution of drug resistant malaria parasites. 15th
International conference. CNIC, 28 June – 1st July 2010, Havana, Cuba
The brunt of mutations conferring drug resistance on the fitness of malaria
parasites. The 1st Africa Health Research Organization (AHRO) International
Malaria Symposium on Clinical Pharmacology of Antimalarial Drugs , Accra,
Ghana, 12-13 August 2008.
Fitness cost of drug resistance in malaria parasites "The 1st International Congress
on Tropical Diseases in Sudan”, Sudan University of Science and Technology 24-
26 Nov 2007, Khartoum, Sudan
Babiker H.A. et al. Plasmodium falciparum is highly infectious and genetically
complex in mosquitoes. Second Annual BioMalPar Conference on the Biology and
Pathology of the Malaria Parasite, Heidelberg, Germany, 5-8th April 2006.
Unstable malaria: the influence of the dry season: Plasmodium falciparum
population is stable and genetically complex. Royal Society of Tropical Medicine
and Hygiene, London, March, 1998
Oral presentation
Hamza Babiker, Amal Gadalla, Petra Schneider, Elkhansaa Nassir, Abdel-Muhsin
A Abdel-Muhsin, Thomas Churcher & Sarah Reece. Seasonality of gametocytes
density among asymptomatic Plasmodium falciparum carriers. American Society
for Tropical Medicine and Hygiene, Philadelphia,USA, 30 Oct-3rd Nov 2015
Salama Al-Hamidhi, Mohammed. H. Tageldin, William Weir, Amira Al-Fahdi,
Eugene Johnson, Patrick Bobade, Mohamed Idris, Badar Alqamashoui, Albano
Beja-Pereira, Jane Kinnaird, Brian Shiels, Andy Tait, Hamza Babiker ·
population genetic analysis of Theileria annulata in Oman . Conference:
Apicomplexa in Farm animals 3rd international meeting. Edinburgh, UK, June
2015.
Amal Gadalla, Petra Schneider, Elkhansaa Nassir, Abdel-Muhsin A Abdel-
Muhsin, Thomas Churcher & Sarah Reece and Hamza Babiker. Gametocytes and
multiple-clone carriage among long lasting asymptomatic Plasmodium falciparum
24
carriers in absence of transmission. British Society for Parasitology meeting 2014,
Cambridge, UK 6th-9th April 2014
Babiker HA. et al. Genetic diversity and distribution of drug resistance markers
among Plasmodium falciparum in sites in the Arabian Peninsula. British Society
for Parasitology meeting 2013, Bristol 8th-11th April 2013
Babiker HA. et al. Source of drug resistant Plasmodium falciparum in a potential
malaria elimination site in Saudi Arabia. Singapore Malaria Network Meeting
2012, Singapore 16-17 Feb 2012.
Babiker HA. et al. Genetic diversity of gametocytes of Plasmodium falciparum
and their infectiousness to Anopheles gambiae. 3rd Annual BioMalPar Conference
on the Biology and Pathology of the Malaria Parasite, Heidelberg, Germany, 10-
13th April 2007.
Babiker HA. et al. Fitness cost of drug resistance in malaria parasites.
International congress on infectious & tropical diseases, Muscat 4-7th December
2006
Babiker H.A. et al. Plasmodium falciparum is highly infectious and genetically
complex in mosquitoes” ICOPA XI Conference. 6-11 August 2006.
Babiker H.A. et al. Increased prevalence of drug-sensitive P. falciparum in
absence of drug pressure in the dry and transmission-free season of eastern Sudan”
. Multilateral Initiative for Malaria in Africa, 4th international meeting, Yaoundé,
Cameroon, 12-18th November 2005.
Babiker H.A. et al. Plasmodium falciparum in The Gambia: persistence in the dry
season and increased complexity in mosquitoes in the wet season. British Society
for Parasitology, Nottingham, 5th to 8th April 2005
Babiker HA. et al. Characterisation of P. falciparum gametocytes that persist
during the lengthy dry season of eastern Sudanese. Scottish University Molecular
Parasitology Group, Kindrogen, 11th to 13th May 2001.
Babiker HA. et al. Characterisation of P. falciparum gametocytes that persist
during the lengthy dry season of eastern Sudanese”. British Society for
Parasitology, Glasgow, 10th to 21th September 2001.
Babiker HA. et al. Detection of sub-patent P. falciparum gametocytes production
during the dry season of eastern Sudan. London Molecular Parasitology Club, One
day symposium of the Royal Society of Tropical Medicine and Hygiene, London,
8th July 1999.
Babiker HA. et al. Genetic characterization of dry season P. falciparum in a
Sudanese village with marked seasonal transmission. British Society for
Parasitology, Glasgow, 9th to 11th September1996.
25
Babiker HA. et al. Population structure of P. falciparum in villages with different
malaria endemicity in Africa. British Society for Parasitology, London, 19th to 21st
September 1995.
Babiker HA. et al. Crossing between strains of the malaria parasite P.
falciparum.National Institute for Medical Research Tanzania, 11th Annual Joint
Scientific Conference, 22nd to 25th February 1993, Arusha, Tanzania
Babiker HA. et al. Prevalence of cross-fertilization in P. falciparum in Tanzania.
British Society for Parasitology, London, 13th to 14th February 1992.
Babiker HA. et al. Genetics of P. falciparum in a small village in Sudan.
European Network of Laboratories, Molecular genetics of parasite and vector,
Montpellier, France, 4th to 7th February 1991.
Babiker HA. et al. Genetic diversity of Plasmodium falciparum in a Sudanese
village. British Society for Parasitology, Edinburgh, 13th to 16th February 1991.
Poster presentation.
Amal A.H. Gadalla, Thomas Churcher, and Hamza Babiker. Growth advantage
of wild-type over drug resistant Plasmodium falciparum genotypes among
asymptomatic carriers in absence of therapy. American Society for Tropical
Medicine and Hygiene, Atlanta, USA, 13th-17th Nov 2016.
Amira Al-Fahdi, Salama Al-Hamidhi, Mohammed. H. Tageldin, Patrick Bobade,
Eugene Johnson, Badar Alqamashoui, Abdel-Rahim Hussain, Hamza Babiker.
Host and breed variation in susceptibility of livestock to natural Theileria sp
infection in Oman. Regional Confrence for Animal genetic resources
conservation. Muscat, 23-24 Feb 2016.
Hamza Babiker, Amal Gadalla, Petra Schneider, Elkhansaa Nassir, Abdel-
Muhsin A Abdel-Muhsin, Thomas Churcher & Sarah Reece. Seasonality of
gametocytes density among asymptomatic Plasmodium falciparum carriers.
American Society for Tropical Medicine and Hygiene, Philadelphia, USA, 30
Oct-3rd Nov 2015
Salama Al-Hamidhi, Mohammed. H. Tageldin, William Weir, Amira Al-Fahdi,
Eugene Johnson, Patrick Bobade, Mohamed Idris, Badar Alqamashoui, Albano
Beja-Pereira, Jane Kinnaird, Brian Shiels, Andy Tait, Hamza Babiker ·
population genetic analysis of Theileria annulata in Oman . Conference:
Apicomplexa in Farm animals 3rd international meeting. Edinburgh, UK, June
2015.
Amal Gadalla, Petra Schneider, Elkhansaa Nassir, Abdel-Muhsin A Abdel-
Muhsin, Thomas Churcher & Sarah Reece and Hamza Babiker. Gametocytes
and multiple-clone carriage among long lasting asymptomatic Plasmodium
falciparum carriers in absence of transmission. British Society for Parasitology
meeting 2014, Cambridge, UK 6th-9th April 2014
26
Mohammed H. Tageldin1 and Huda K.N. Al-Weheibi, Muna Al-Rubkhi, Salama
Al-Hamidhi, Mohamed Idris, Andy Tait, Hamza Babiker. Theileria parasites in
Oman. Apicomplexan in farm animals, Kuşadası, Turkey, October 31-
November 2, 2013
Amal Gadalla, Khansaa Nasser, Petra Schnieder, Sarah Reece, Hamza A.
Babiker. Gametocytes and multiple-clone carriage among long lasting
asymptomatic Plasmodium falciparum carriers in absence of therapy. Biology
and Pathology of the malaria parasites. 9th BioMal Par/EVIMalaR conference,
Heidelberg, Germany, 13-15 May 2013.
Salama Al-Hamidhi, Mohammed A.K. Mahdy, Saad M. Bin Dajem, Adel Ali H.
Al-Sheikh, Zainab Al-Hashami, Hissa Al-Farsi, Abdulsalam M. Al-mekhlafi,
Mohamed Ahmed Idris, Albano Beja-Pereira and Hamza A. Babiker. Genetic
diversity of Plasmodium falciparum and distribution of drug resistance genes in
the Arabian Peninsula. Biology and Pathology of the malaria parasites. 9th
BioMal Par/EVIMalaR conference, Heidelberg Germany, 13-15 May 2013.
Babiker HA. Transmission and cross-mating of high-level resistance
Plasmodium falciparum dhfr haplotypes in the Gambia. British Society for
Parasitology, Edinburgh, 11th to 13th April 2009.
Babiker H.A. et al. Plasmodium falciparum in The Gambia: persistence in the
dry season and increased complexity in mosquitoes in the wet season”
Multilateral Initiative for Malaria in Africa, 4th international meeting, Yaoundé,
Cameroon, 12-18th November 2005.
Workshop attendance
1. Computational Biology workshop, SQU, College of Medicine and Health
Sciences, SQU, Muscat, Oman, 24-28 January 2008.
2.Certificate Course in Health Professions Education, College of Medicine and
Health Sciences, SQU, Muscat, Oman, 13th-15th February 2007.
3. Workshop on Student Assessment, College of Medicine and Health Sciences,
SQU, Muscat, Oman, 13th-15th February 2007.
4. MMV/WHO Informal consultation on Methods and Techniques for Clinical Trails
on Antimalarial Dug Efficacy: Genotyping to identify Parasite Populations ,
Amsterdam, The Netherland, May, 29-30th ,2007,
5. Postgraduate supervision in Sciences and Engineering. College of Science and
Engineering, University of Edinburgh, August, 30th, 2006.
6 Advanced regional training program in bioinformatics, SQU, WHO, College of
Medicine and Health Sciences, SQU, Muscat, Oman, 10-14 December 2005.
