Radiation Technology for Industries, the Role of IAEA 01/IT1 Bumsoo Han... · - Sharing and Developing Protocols to Further Minimize Radioactive Gaseous Releases to the Environment

Presentation at NICSTAR 2018, 5-7 March 2018, Mumbai, India

Radiation Technology for Industries, the Role of IAEA

Bumsoo Han / Sunil Sabharwal

Radioisotope Products and Radiation Technology Section

Department of Nuclear Sciences and Applications

International Atomic Energy Agency



- Introduction to IAEA

- Radiation Technology Development at the

Division of Physical & Chemical Sciences

- Priorities

+ Education/Training/Qualification/Regulation

+ Research and Development (CRPs)

+ Implementation of Technologies (TC)

- Others


Set up as the world´s

"Atoms for Peace“

organization in 1957

In 1953, Dwight Eisenhower, the President of the United States, called for the establishment of an international atomic energy agency


169 Member States

promotes

safe, secure and peaceful

nuclear technologies.



• 2300 professional and support staff

• Headquarters in Vienna

• 2 scientific laboratories and research centres

• Liaison offices in New York and Geneva





http://www.un.org/sustainabledevelopment/energy/

http://www.un.org/sustainabledevelopment/climate-change-2/

http://www.un.org/sustainabledevelopment/hunger/

http://www.un.org/sustainabledevelopment/economic-growth/

http://www.un.org/sustainabledevelopment/oceans/

http://www.un.org/sustainabledevelopment/health/

http://www.un.org/sustainabledevelopment/infrastructure-industrialization/

http://www.un.org/sustainabledevelopment/biodiversity/

http://www.un.org/sustainabledevelopment/education/

http://www.un.org/sustainabledevelopment/inequality/

http://www.un.org/sustainabledevelopment/peace-justice/

http://www.un.org/sustainabledevelopment/gender-equality/

http://www.un.org/sustainabledevelopment/cities/

http://www.un.org/sustainabledevelopment/globalpartnerships/

http://www.un.org/sustainabledevelopment/poverty/

http://i1.wp.com/www.un.org/sustainabledevelopment/wp-content/uploads/2015/08/UNSustainableDevelopmentGoals_Brand-01.png?resize=2550,544

http://www.un.org/sustainabledevelopment/sustainable-consumption-production/

http://www.un.org/sustainabledevelopment/water-and-sanitation/


Three Pillars: Technology

Safety & Security

Safeguards & Verification

Six Departments: Nuclear Sciences & Applications (NA)

Nuclear Energy (NE),

Nuclear Safety (NS),

Safeguards (SG),

Management (MT),

Technical Cooperation (TC)

IAEA Organization


Nuclear Sciences and Applications contribute to…

Promoting food security and sustainable

agricultural development

(FOOD & AGRICULTURE,

NAFA)

Improving the diagnosis and treatment of diseases and nutrition (HUMAN HEALTH, NAHU))

Making more, and cleaner water available to

more people (WATER RESOURCES, NAPC)

Understanding and protecting the

environment (ENVIRONMENT LABORATORIES,

NAEL)

Providing knowledge & expertise for

science (NUCLEAR PHYSICS) & industry (RADIOISOTOPE

PRODUCTION & RADIATION TECHNOLOGY, NAPC)



- Joint FAO/IAEA Division of Nuclear

Techniques in Food and Agriculture

- Division of Human Health

- Division of Physical & Chemical Sciences

- IAEA Environment Laboratories (Monaco)



- Joint FAO/IAEA Division of Nuclear

Techniques in Food and Agriculture

+ Soil and Water Management and Crop Nutrition Section

+ Plant Breeding and Genetics Section

+ Animal Production and Health

+ Insect Pest Control Section

+ Food and Environmental Protection

Promoting food security and sustainable

agricultural development

(FOOD & AGRICULTURE,

NAFA)



- Division of Human Health

+ Nuclear Medicine and Diagnostic Imaging Section

+ Applied Radiation Biology and Radiotherapy Section

+ Dosimetry and Medical Radiation Physics Section

+ Nutritional and Health-Related

Environmental Studies Section

Improving the diagnosis and treatment of diseases and nutrition (HUMAN HEALTH, NAHU))



- IAEA Environment Laboratories

(Monaco)

+ Radiometric Laboratory

+ Radioecology Laboratory

+ Marine Environmental Studies Laboratory

+ Terrestrial Environment Laboratory

Understanding and protecting the

environment (ENVIRONMENT LABORATORIES,

NAEL)



- Div. of Physical & Chemical Sciences

+ Physics Section

+ Radioisotope Products and Radiation Technology Section

+ Isotope Hydrology Section

+ Nuclear Data Section

Providing knowledge & expertise for

science (NUCLEAR PHYSICS) & industry (RADIOISOTOPE

PRODUCTION & RADIATION TECHNOLOGY, NAPC)

Making more, and cleaner water available to

more people (WATER RESOURCES, NAPC)






Department of Nuclear Sciences and Applications - Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture + Soil and Water Management and Crop Nutrition Section

+ Plant Breeding and Genetics Section

+ Animal Production and Health Section

+ Insect Pest Control Section

+ Food and Environmental Protection Section

- Division of Human Health + Nuclear Medicine and Diagnostic Imaging Section

+ Applied Radiation Biology and Radiotherapy Section

+ Dosimetry and Medical Radiation Physics Section

+ Nutritional and Health-Related Environmental Studies Section

- Division of Physical and Chemical Sciences + Physics Section

+ Radioisotope Products and Radiation Technology Section

+ Nuclear Data Section

+ Isotope Hydrology Section

- IAEA Environment Laboratories (Monaco) + Radiometric Laboratory

+ Radioecology Laboratory

+ Marine Environmental Studies Laboratory

+ Terrestrial Environment Laboratory


Programme 2.5

Programme Description/Objectives

Programme 2.5

Radioisotope Production and

Radiation Technology

Sub-programme 2.5.1: Radioisotope Products for Cancer Management and non-Communicable

Diseases

2.5.1.001 Development and production of medical

radioisotopes

2.5.1.002 Development of diagnostic and therapeutic

radiopharmaceuticals

Sub-programme 2.5.2: Radiation Technology for Health Care and

Industrial Applications

2.5.2.001 Industrial applications of radioisotopes

and radiation techniques

2.5.2.002 Radiation technologies for health care

and environmental applications


Radioisotope

production

Radiopharmaceutical

production Diagnostic or

therapeutic

application

Nuclear Medicine Procedure


Cyclotrons Research reactor

Radionuclide

generator

Production of Radioisotopes

http://en.wikipedia.org/wiki/File:ThermalFissionYield.svg


• Radiopharmaceuticals for SPECT (Single Photon Emission Computed Tomography):Tc-99m, In-111, Ga-67…

• Radiopharmaceuticals for PET (Positron Emission Tomography): F-18, Ga-68, Cu-64….

• Radiopharmaceuticals for therapy: Lu-177, Y-90, I-131, alpha emitters

Radioisotopes and Radiopharmaceuticals for Diagnosis and Therapy

PET/CT SPECT/CT

Layout Hot cell

Synthesis

Module


Radiotracers - NDT


Radiation Technologies (NDT)


Materials Modification


Materials Modification

Presentation at NICSTAR 2018, 5-7 March 2018, Mumbai, India 28

Radiation Technologies (sterilization)


Radiation Technologies









- Priorities




- Others


Education / Training / Qualification / Regulation

Research and Development (CRPs)

Implementation of Technologies (TC)

Priorities


Education / Training / Qualification /

Regulation Three African students started

their Masters program on Radiopharmacy at the University of Stip, Macedonia.

E-learning modules are being develop for Radiopharmacy

education together with Macedonia

Regional (AFRA) Training Course on Cleaner and Safer Management of Industrial Processes - Column Scanning Applications

Supporting Sustainability and Networking of National Nuclear Institutions in Asia and the Pacific Region by training of Secondary School Students


Coordinated Research Activities




CRPs (RI and Radiopharmaceuticals) Concluded CRP

- Development of Agents for Imaging Central Neural Systems (CNS) receptors Based on Tc-99m (1995~2001) - Tc-99m Labelled Peptides for Imaging of Peripheral Receptors (1995~1999) - Development of Kits for Radio-immunometric Assays of Tumour Markers (1997~2001) - Development of Radioactively labelled Cancer Seeking Biomolecules for Targeted Radiotherapy (1997~2001) - Development of Kits for TC-99m Radiopharmaceuticals for Infection Imaging (2000~2003) - Development of Radio-immunometric Assays and Kits for Non Clinical Applications (2001~2005) - Comparative laboratory Evaluation of Therapeutic Radiopharmaceuticals (2002~2005) - Development of Tc-99m based Small Bio-molecules Using Novel Tc-99m Cores (2002~2006) - Development of Generator Technology for Therapeutic Radionuclides (2004~2008) - Development of Therapeutic Radiopharmaceuticals Based on 177Lu for Radionuclide Therapy (2006~2010) - Development and Preclinical Evaluations of Therapeutic Radiopharmaceuticals Based on Lu-177 and Y-90 labelled monoclonal antibodies and peptides (2011~2015) - Accelerator-based Alternatives to Non-HEU production of Mo-99/Tc-99m (2012~2015)

Active CRP

- Therapeutic Radiopharmaceuticals (67Cu, 186Re, 47Sc) (2016~) - Cu-64 radiopharmaceuticals for Theragnostic Applications (2016~) - New Ways of producing Tc-99m and Tc-99m generators (Beyond fission and cyclotron methods) (2017~) - Nano-sized Delivery Systems for Radiopharmaceuticals (2014~2019)

New (2018 ~)

- Development of a gamma CT System with high field applicability (2018~) - Radiation Inactivation of Bio-hazards Using High Powered Electron Beam Accelerators (2018~)


CRPs (Environmental Applications) Concluded

- Nuclear Techniques for the Evaluation of healing Pathway of Pollutant Damage in the Environment (1992~1996) - Irradiation Treatment of Water, Wastewater and Sludge (1995~2000) - Nuclear Analytical techniques in Archaeological Investigations (1996~2000) - Remediation of Polluted Waters & Wastewaters by Radiation Processing (2002~2006) - Radiation Treatment of Wastewater for Reuse with Particular Focus on Wastewaters containing Organic Pollutants. (2011~2015) - Application of Two and Three Dimensional neutron Imaging with Focus on Cultural Heritage research (2012~2018)

Active

- Developing radiation treatment methodologies and new Resin Formulation for Consolidation and Preservation of Archived Materials and Cultural Heritage Artefacts (2015~)

New (2018 ~)

- Radiation Inactivation of Bio-hazards Using High Powered Electron Beam Accelerators (2018~)

Planned (2018 ~)

- Radiation Treatment of Emerging Pollutants (2019~)


CRPs (Radiotracer, NDT) Concluded

- Validation of Nuclear Techniques for Analysis of Precious and Rare metals in Mineral Concentrates (1997~2000) - Development and Validation of Speciation Analysis Using nuclear Techniques (2000~2004) - New Applications of Prompt Gamma Neutron Activation Analysis (PGNAA) (2001~2005) - Evaluation and Validation of Radioisotopes Generators-Based Radiotracer for Industrial Applications (2007~2011) - Radiometric Methods for Measuring and Modelling Multiphase Systems (2012~2016)

Active - Radiometric Methods for Exploration and Process Optimization in Mining and Mineral Industries (2014~2018) - Sharing and Developing Protocols to Further Minimize Radioactive Gaseous Releases to the Environment in the Manufacture of Medical Radioisotopes, as Good Manufacturing Practice (2015~ - Radiometric Methods and Modelling for Sediment Transport and Dispersion of Particles and Pollutants from Outfalls (2016~


Concluded

- Radiation Modification of Polymers for Industrial and Medical Use. (1984~1989) M

- Radiation Damage to Organic materials in Nuclear and Radiation Environments (1985~1989) M

- Radiation Processing Technology Applications in Bioengineering (1988~1994) M

- Stability and Stabilization of Polymers under Irradiation (1993~1997) G

- The Use of Radiation Processing to prepare Biomaterials for Applications in Medicine (1995~2000) G

- Improvement of Physical Properties of Radiation Vulcanized Rubber Latex (RVNRL) –(RCA) (1997~2000) G

- Radiation Processing of Indigenous Natural Polymer (RCA) (1997~2000) G

- The Use of Radiation Processing for Sterilization or decontamination of Pharmaceuticals and pharmaceutical raw material (1998~2001) G

- Development of Radiation-Processed products of natural Polymers for Application in Agriculture, Healthcare, Industry and Environment (2008~2012) A

- Radiation Curing of Composites for Enhancing their Features and Utility in Healthcare and Industry (2010-2014) A

- Development of Novel Adsorbents and Membranes by Radiation Grafting for Selective Separation Purposes (2007~2010)S

- Nanoscale Radiation Engineering of Advanced Materials for Potential Biomedical Applications (2008-2012) A

- Application of Radiation Technology in the Development of Advanced Packaging Materials for Food Products (2013~2016)H

Active CRP

- Nano-sized Delivery Systems for Radiopharmaceuticals (2014~2019)

- Instructive Surfaces and Scaffolds for Tissue Engineering by Radiation (2014~2019)

Planned (2018~)

- Nano-science and Technology in Industrial Applications (2018~2022)

- Grafted Membrane for Cleaner and Sustainable Energy (2019~2023)

- Recycling of Polymeric Materials (2020~2024)

CRPs (Material Sciences)



IAEA TC Programme

• The technical cooperation (TC) programme is the IAEA’s main vehicle

for delivering services from across the house to Member States

• The Department of Technical Cooperation is responsible for managing

the TC programme.

• The technical Departments are responsible for the technical integrity of

the programme

TC programme is guided by:

• IAEA Statute (1956)

• TC Strategy (est. 1997, rev. 2002)

• Agency’s Medium Term Strategy (2012-2017)

• Decisions of Governing Bodies

• Revised Supplementary Agreement

• INF/CIRC 267 (Guiding Principles & General Operating Rules)



IAEA TC Programme TC Programme - Quick Facts

• Recipients: all IAEA Member States are eligible for TC assistance

• 169 Member States

• 146 recipient countries

• ~ 80% of recipients are non-nuclear power countries

• 37 Member States are Least Developed Countries (LDCs)

• Total Budget in 2016: € 113.2 million (€ 82 million TCF)

TC Programme Funding Sources

• TCF (Technical Co-operation Fund)

• Voluntary contributions from all Member States

• National Participation Costs (NPCs)

• Funds are used for approved TC programme activities in all Member

States

• Extrabudgetary + Peaceful Uses Initiative (PUI)

• Donor funding from Member States, other international organizations,

NGOs and the recipient government itself (Government Cost Sharing).


IAEA TC Programme

TC Programme Activities – 2016

Support provided to 146 countries and territories

- 914 Active Projects

- 3777 Expert and lecturer assignments

- 5820 meeting participants

- 3114 training course participants

- 1701 fellows and scientific visitors

- Field procurement:

o 1714 Purchase Orders

o € 30.2 million

TC areas of work

• Human Health

• Food and Agriculture

• Water and Environment

• Nuclear Energy

• Safety and Security






- Priorities




- Others



IAEA Collaborating Centres

Collaborating Centre concept is to add value to and to leverage synergies by:

o Sharing research advances, scientific information, knowledge and experience with Member States

o Increasing stakeholder participation in efforts to implement norms and standards

o Improving project and programme identification, design, delivery and management

With this in view , in the area of radiation processing the following five

organizations have been designated as IAEA Collaborating Centres:

1. Malaysian Nuclear Agency (MNA) for radiation processing of natural polymers and nano-materials

(2006)

2. Institute of Nuclear Chemistry and Technology (INCT), Poland, for radiation technology and

technological dosimetry ( 2010)

3. The Advanced Radiation Technology Institute (ARTI) of Korea Atomic Energy Research Institute

(KAERI), for environment remediation, advanced materials and food irradiation (2012).

4. The National Centre for Electron Beam Research (NCEBR), USA, for food, health and

environmental applications (2014).

5. National Institute of Nuclear Research (ININ), Mexico, for safe operation, maintenance and

upgradation of gamma irradiation facilities (2017).


IAEA Collaborating Centres

IAEA

Malaysian Nuclear Agency (MNA) on : "Radiation Processing of Natural Polymers and Nano-materials"

Institute of Nuclear Chemistry and

Technology (INCT) on “Radiation

Technology and Technological

Dosimetry”

Advanced Radiation Technology Institute (ARTI) of KAERI, in

the three areas: environment remediation,

advanced materials and food irradiation.

National Institute of Nuclear Research

(ININ), Mexico in the field: Safe Operation,

Maintenance and Upgradation of

Gamma Irradiation Facilities

National Center for Electron Beam

Research (NCEBR) on 2014


https://www.iaea.org/publications

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Documents

Radiation Technology for Industries, the Role of IAEA 01/IT1 Bumsoo Han... · - Sharing and Developing Protocols to Further Minimize Radioactive Gaseous Releases to the Environment