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Rapid Reader Technology, New Technological Approaches to Assessment of Alcohol Abuse
Alastair van Heerden HSRC
3 Slide /
Plan
01 Big Picture
03 Research Application (focusing on Alcohol)
02 Current Buzz
BIG PICTURE
Section 1 0f 4
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6 Slide /
Eras of computing technology
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Corporate
Personal
Ambient
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• 1890s – 1950s
• Massive growth in people
and things demanded
single-purpose systems
that could count
• Made possible: US Social
Security program
M
Tabular
• 1950s - Today
• Increasing complexity of
business and society
required multi-purpose
systems that could apply
logic.
• Made possible: land on
the moon
Z
Code
• Today - Future
• Continually changing
scale and complexity
required real-time
adjustments.
• Sense, learn and
understand to support
decision making.
• Made possible: ??
H
Cognitive
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PC, Internet and Mobile Eras
Tech product cycles are mutually reinforcing interactions between platforms and applications. New
platforms enable new applications, which in turn make the new platforms more valuable, creating a
positive feedback loop. Smaller, offshoot tech cycles happen all the time, but every once in a while —
historically, about every 10 to 15 years — major new cycles begin that completely reshape the
computing landscape. The PC enabled entrepreneurs to create word processors, spreadsheets, and
many other desktop applications. The internet enabled search engines, e-commerce, e-mail and
messaging, social networking, and many other services. Smartphones enabled mobile messaging,
mobile social networking, and on-demand services like ride sharing. Today, we are in the middle of the
mobile era. It is likely that many more mobile innovations are still to come.
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3 Waves
Ubiquitous
Personal
Mainframe
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Small, Cheap, Fast, Efficient, Everywhere
CURRENT BUZZ
Section 2 0f 4
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Buzzwords
IoT
Alternative Reality (VR / AR)
Block Chain
APPLICATION TO RESEARCH
Section 3 0f 4
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The Inspiration
Portable Diagnostic Inexpensive
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CCGs Informed Empowered Effective
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Data Collection Mode effect, quality improvement,
improved time to analysis
Digital Exhaust Activity, travel, social engagement, sleep
patterns, etc.
Interventions SMS, Messaging, unidirectional, bi-
directional, real-time, reminders
Enhancements Attachments, Wearables, Glasses,
AR/VR, imaging microscopy and sensing
diagnostics, rapid readers
Mobiles
Areas of Research
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Data Collection
Tourangeau R., Rips L., Rasinski K. (2000)
Self-administration
Computerisation
Auditory presentation
Privacy
Legitimacy
Cognitive burden
Level of Reporting
Accuracy
Reliability
Rate of Missing
Telephone
Face-to-Face
Paper Computer
OCR Fax
Web E-mail Disk by Mail
CATI TDE IVR/ACASI
CAPI
SAQ
Walkman
Text- CASI
Audio- CASI
Video- CASI
Groves, R. (2004)
Telephone
Face-to-Face
Paper Computer
OCR Fax
Web E-mail Disk by Mail
CATI TDE IVR/ACASI
CAPI
SAQ
Walkman
Text- CASI
Audio- CASI
Video- CASI
Pervasive Devices
MPAPI
MPASI
Adapted, Groves, R. (2004)
IoT
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Behavioural Functionality of Mobile Apps in Health Interventions
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Systematic Review n=24
Behavioral Component
2
Payne et al. (2015)
Retention & Acceptability
x
Intervention Efficacy
W
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Digital Exhaust
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Ginger.io
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Enhancements
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Moore’s Law
Greenbaum et al. (2015)
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Point of Care Diagnostics
Existing diagnostic instrumentation usually requires sophisticated infrastructure, stable
electrical power, expensive reagents,
long assay times, and highly trained personnel
which is not often available in limited resource settings.
Sharma, S. et al. (2015)
Ozcan, A. (2013)
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POC
$27.5 billion
Advantages
LMIC Challenge
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LUCAS
Lensfree x
Ultra wide field
u
Cell Monitoring Q
Ozcan, A. (2013)
Shadow imaging O
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Microfluidics
Can be paper based
x
Multiple assays
u
No specialized training
Q
Easy interpretation of results
O
Sharma, S. et al. (2015)
THANK YOU
End
