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Recombination
Early Experiments:
1947 Alfred Hershey and Max Delbrück
1961 Matthew Meselson and Jean Weigle
*Homologous Genetic Recombination
*Site Specific Recombination
*Transposition
Homologous Recombination
*Two broad categories (pathways):
Homologous Recombination
Homologous Recombination
RecBCD Pathway
http://www.esrf.eu/news/spotlight/spotlight13dnarepair/spotlight_dna_repair_fig1s
RecBCD Pathway
RecA filament
RecA at work
RuvAB facilitate branch migration
RuvAB facilitate branch migration
Gene Targeting
in Embryonic Stem Cells
www.nobelprize.org
Gene Targeting in Embryonic Stem Cells
www.nobelprize.org
www.nobelprize.org
![Studium 1566 in Freiburg Studium 1582 in Orléans · 52 WEIGLE, Matrikel der deutschen Nation in Siena S. 55: [1575] Johannes Laurentius Faust Moguntinus ½ sc. 53 WEIGLE, Matrikel](https://img.pdfslide.net/doc/110x75/5fe7d7cfc877ba11c1196a09/studium-1566-in-freiburg-studium-1582-in-orlans-52-weigle-matrikel-der-deutschen.jpg)
