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    Colorectal Polyp Detection using

    CAD-CTC System Integration

    Under the guidence of

    Prof. P.Tamije Selvy,

    Presented ByM.VANITHA

    II M.E CSE 08

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    ABSTRACT

    Computed Tomography Colonography(CTC) is a rapidly evolving noninvasive

    medical investigation that is viewed by

    radiologists as a potential screening

    technique for the detection of colorectalpolyps. The aim of this paper is to detail the

    implementation of a fully integrated CAD-

    CTC system that is able to robustly identifythe clinically significant polyps in the CT

    data.

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    Contd. The CAD-CTC system described in this paper is a

    multistage implementation whose main system

    components are:1.automatic colon segmentation,2.candidate surface extraction,

    3.feature extraction and 4.classification. The

    developed system has been evaluated on synthetic

    and real patient CT data acquired with standard

    and low-dose data.

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    Literature Review

    Paper : G.Iordanescu, P.J. Pickhardt, J.R. Choi, andR.M. Summers, Automated seed placement for colon

    segmentation in CT colonogrphy, Acad. Rad., vol. 12, pp.

    182-190, 2005.

    Abstract : Present an algorithm to automatically locateseeds for colon segmentation in computed tomography

    colonography (CTC).

    The information inferred from this :

    Fully automatic seed placement for colonic segmentation

    is feasible in the majority of cases without seeding of

    undesired extracolonic air was analyzed.

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    Contd Paper : O.Ghita and P.F.Whelan,A bin picking system

    based on depth from defocus,Mach. Vis. Appl., vol. 13,

    no. 2, pp. 234-244, 2003.

    Abstract : Develop versatile bin-picking systemscapable of grasping and manipulation operations, accurate

    3-D information is required

    The information inferred from this :the attitude of the recognized object is evaluated using an

    eigenimage approach augmented with range data analysis.

    The full bin-picking system will be outlined, and a number

    of experimental results will be examined.

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    Contd Paper : G.Kiss,J.Van Cleynenbreugel, M. Thomeer, P.Suetens,

    and G. Marchalc, Computer diagnosis for CT Colonography via

    combination of surface normal and sphere fitting methods,Eur. Rad.,Vol. 12, no. 1,pp.77-81, 2002.

    Abstract :finding an enhanced version of the techniquefor the extraction of the polyp candidate surfaces.

    The information inferred from this : methodsfor the extraction of the polyp candidate surfaces are

    analyzed.

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    Existing System The existing CAD-CTC system can robustly

    identify the clinically significant polyps in

    the CT data. But it generates more false

    positives from the small convex surfaces .In

    that situation the application of these

    systems to clinical studies impractical. Sothe reduction of false positives is very

    important.

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    Proposed System

    The fully integrated CAD-CTC system is able to robustlyidentify the clinically significant in the CT data.

    The proposed system will returns the highest sensitivity in

    Polyp detection.

    The application of this system will be useful in the clinical

    examinations.

    The proposed system will achieve robust polyp detection at alow level of false positives.

    This system has been evaluated on synthetic and real patient

    CT data acquired with standard and low-dose radiation levels.

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    Development Tools

    Hardware requirementsProcessor : Intel Pentium IV

    Processor Speed : 1.4 GHz

    Memory (RAM) : 512 MBHard disk : 40 GB

    Monitor : 15 Color Monitor

    Key board : 104 keys Standard Keyboard

    Mouse : Standard Three button Mouse

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    Development Tools Contd.

    Software requirements

    Operating System : Windows XP

    Language : MAT

    LAB

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    Block Diagram

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    Key Features of MATLAB

    High-level language for technical computing

    Development environment for managing code, files, and data

    Interactive tools for iterative exploration, design, and problemsolving

    Mathematical functions for linear algebra, statistics, Fourieranalysis, filtering, optimization, and numerical integration

    2-D and 3-D graphics functions for visualizing data

    Tools for building custom graphical user interfaces

    Functions for integrating MATLAB based algorithms with

    external applications and languages, such as C, C++, Fortran,Java, COM, and Microsoft Excel

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    Modules

    Automatic colon segmentation

    Candidate surface extraction Feature extraction

    Classification

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    Goal:

    To identify the colons in the CT data

    Steps:

    Surrounding air voxel removal

    Lung detection

    Labelling

    V/L analysis Colon reconstruction

    Algorithm:

    Seeded Region Growing Algorithm

    Automatic colon Segmentaion

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    Candidate Surface ExtractionGoal:

    Extraction of polyp candidate surfaces

    Step:Finding intersection of the normal vectors for a

    number of normal concentration points.

    Algorithms:

    Gaussian weighted averaging operationNon maxima suppression algorithm

    Surface convexity test

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    Data Classification

    Goal: Robustly identify the clinically significant polyps in the

    CT data.

    Steps:

    Training database is created using the featuresdetailed in features extraction for each polyps and

    folds.

    Features of each class is normalized.

    Algorithms:

    Feature Normalized Nearest Neighbor Classifier(FNNN)

    Probabilistic Neural Network (PNN)

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    Comparision of Existing and proposed systen

    with any one of the metrics

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    References

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    Conclusion

    we conclude that robust polyp detection is

    possible even at radiation does as low as 13m

    as / rotation. The required by this system to

    process completely is lower than the time

    required to analyze the data manually. CAD-

    CTC system is fully integrated so its

    performance makes it suitable to be applied in

    clinical examinations.

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    Thank YOU