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WHAT IS IT?WHAT IS IT?
It is a virus that has RNA (ribonucleic acid) as its genetic mateterialIt is a virus that has RNA (ribonucleic acid) as its genetic mateterial
It is usually single-stranded buy may be double strandedIt is usually single-stranded buy may be double stranded
SINGLE-STRANDED RNA VIRUSESSINGLE-STRANDED RNA VIRUSES
Can be further classified into positive-sense and negative-senseCan be further classified into positive-sense and negative-sense
Positive-sense viral RNA is similar to mRNA and can be translated immePositive-sense viral RNA is similar to mRNA and can be translated immediately by host celldiately by host cell
Negative-sense viral RNA must be converted to positive-sense RNA befoNegative-sense viral RNA must be converted to positive-sense RNA before translationre translation
MUTATION RATEMUTATION RATE
RNA viruses generally have higher mutation rates than DNA viruses becRNA viruses generally have higher mutation rates than DNA viruses because the RNA polymerase is likely to commit errors, unlike the DNA polyause the RNA polymerase is likely to commit errors, unlike the DNA polymerase that has the ability to proofread.merase that has the ability to proofread.
DNA VIRUS VS. RNA VIRUSDNA VIRUS VS. RNA VIRUS
DNA virusDNA virus
- Mostly double-stranded- Mostly double-stranded- Higher mutation rate- Higher mutation rate- DNA replication usually t- DNA replication usually takes place in the nucleusakes place in the nucleus- stable- stable- injects genetic code in th- injects genetic code in the host DNA for duplication e host DNA for duplication and decodingand decoding
RNA VirusRNA Virus
- Mostly single-stranded- Mostly single-stranded- RNA replication usually t- RNA replication usually takes place in the cytoplasakes place in the cytoplasmm- unstable- unstable- skips duplication and de- skips duplication and decodingcoding
VIRAL REPRODUCTIVE CYCLEVIRAL REPRODUCTIVE CYCLE
- Virus enters a host cell and injec- Virus enters a host cell and injects its RNA strand and capsidsts its RNA strand and capsids
- The virus uses the host cell's re- The virus uses the host cell's resources to generate a new RNA by sources to generate a new RNA by replicating a template RNA. mRNA replicating a template RNA. mRNA generates new capsids through Rgenerates new capsids through R
NA translationNA translation- Newly formed RNAs and capsids - Newly formed RNAs and capsids fuse together to form a new RNA vfuse together to form a new RNA v
irus.irus.