New drug authorized to administer by

DHS. BUT is limited to

use in a successfully intubated patient.

Description: Neuromuscular blocking (paralyzing) agent

Mechanism of action: Produces neuromuscular blockade by competing with acetylcholine for cholinergic receptors at the motor end plate.

Half-life: Rocuronium has a biphasic distribution. The rapid distribution half-life is 1 to 2 minutes, and the slower distribution half-life is 14 to 18 minutes.

Rocuronium has no effect on consciousness or pain threshold. Therefore, when rocuronium is used, adequate analgesia and sedation should be administered.

Description: Neuromuscular blocking (paralyzing) agent

Mechanism of action: Produces neuromuscular blockade by competing with acetylcholine for cholinergic receptors at the motor end plate.

Half-life: Rocuronium has a biphasic distribution. The rapid distribution half-life is 1 to 2 minutes, and the slower distribution half-life is 14 to 18 minutes.

Rocuronium has no effect on consciousness or pain threshold. Therefore, when rocuronium is used, adequate analgesia and sedation should be administered.

•No effects on HR or BP

•Reliable and controllable duration of action

•Fast onset

•Stable hemodynamics/no histamine release

•Supplied: Solution as 10mg/cc vials of 50mg. Stable for 60 days at room temperature.

It’s effects may be reversed by administering an anticholinesterase such as Prostigimine. Which increases the amount of acetylcholine at the receptors to compete with rocuronium.

But not in EMS scope of practice in AZ Reversal of blockade virtually is never indicated

following emergency airway management. Atropine 0.01mg per kg IV is given to block

excessive muscarinic stimulation (SLUDGE syndrome)

.

Midalzolam 5mg/PRN Morphine Same MS protocol for pain

2 mg initial dose 2-6 mg subsequent doses max. 20mg

Remember: None of the previously reviewed medications: Etomidate, Succinylcholine, Versed, and Rocuronium are analgesics. Treat your patients pain!

Short-acting sedative hypnotic Benzodiazepine Water-soluble CNS depressant and causes significant

amnesia following administration Has some muscle relaxant thus serves to

calm and sedate patients, relax skeletal muscles, and, in high doses, causes sleep.

Midazolam DOES NOT have analgesic properties.