Saarland University, 7 – 9 March 2016 · 2016-03-04 · interests are the biopharmaceutical investigations of semisolid dosage forms for dermatological applications, the development

Saarland University, 7 – 9 March 2016

Welcome to BioBarriers 2016Dear Colleagues,

This year BioBarriers is taking place for the 11th time. What started in 1997 under the nickname Cell Course as a winter school for graduate students has meanwhile developed into a regular biennial scientific conference with international visibility. Still, however, it remains our intention to foster especially young scientists by bringing them into dialogue with some of the established Gurus in the field. In such spirit, we hope to provide a pleasant and creative atmosphere.

This year’s meeting also coincides with the Annual Meeting of the Controlled Release Society’s (CRS) Local Chapter Germany, which this year celebrates its 20th anniversary. The first day of BioBarriers 2016 (Monday) is therefore entirely dedicated to the topic of controlled release and advanced drug delivery technologies. As typical for the CRS Local Chapter meeting, there will also be plenty of opportunities for young scientists to present their work as a poster or short podium presentation.

We also appreciate the collaboration with and generous support from the Galenus Foundation and the Center for Alternatives to Animal Testing Europe (CAAT-EU), who each are sponsoring invited speakers from abroad on Tuesday, the second day of the conference. The nano-bio interface, cell-and tissue-based in vitro models and infectious diseases are the focus of the program on this day.

Wednesday features contributions from three EU projects: the ITN’s “PathChooser” and “NABBA”, as well as the IMI project “COMPACT”, all sharing Biological Barriers as a common theme. In the afternoon there will be two courses on topics most relevant to graduate education, namely good scientific practice and bibliometrics, the latter kindly sponsored by Elsevier BV.

For those interested in getting some hands-on experience with innovative quasi-vivo technologies, Kirkstall Ltd. has been kind enough to offer a two-day workshop on Thursday and Friday, as a satellite event immediately following the conference.

Last but not least, two evening events, generously contributed and arranged by Across Barriers and PHAST, will provide opportunities to continue discussions over some drinks, food and music.

By the time of the deadline, we had received an impressive number of 114 abstracts and approximately 200 registrations from five continents, in addition to a lineup of about 29 invited speakers. Therefore, BioBarriers 2016 promises to be more stimulating than ever.

Enjoy BioBarriers 2016 and have a pleasant stay in Saarbrücken!

Claus-Michael Lehr

On behalf of the Program Committee

Program CommitteeClaus-Michael Lehr is Professor at Saarland University, and also cofounder and head of the department “Drug Delivery” at the recently established Helmholtz Institute for Pharmaceutical Research Saarland (HIPS). Together with his long lasting colleague Ulrich Schäfer, he developed the BioBarriersconference series and acts as program chair since its beginning in 1997. He received numerous awards and memberships and serves as expert reviewer for research institutions, international corporations and journals. In 2015, the British Magazine „The Medicine Maker“ listed Prof. Lehr as one of the Top 100 drug researchers in the world.

Ulrich Schäfer studied Pharmacy at Kiel University and obtained his Ph.D. at Saarland University in 1980. In December 2010, he was appointed apl Professor by Saarland University. His main research interests are the biopharmaceutical investigations of semisolid dosage forms for dermatological applications, the development of in vitro models determining penetration and permeation of drugs into human skin, and in silico modeling of skin absorption. As second research area, he is involved in research of non-cellular barriers of the lung and pulmonary toxicological and drug delivery aspects of nano-sized systems. Although retired since April 2013, he is still closely connected to Saarland University.

Marc Schneider studied physics and graduated at the Free University Berlin in 1998. In 2002 he finished his PhD at the Max Planck Institute of Colloids and Interfaces, Potsdam. Three Post Doc positions in Potsdam, Genoa and Saarbrücken resulted in becoming professor for Pharmaceutical Nanotechnology and full professor for Pharmaceutics and Biopharmacy at Philipps University Marburg, Germany. Since February 2015 he is head of the institute of Biopharmaceutics and Pharmaceutical Technology at Saarland University. His main research focuses on synthesis and characterisation of novel nano / microparticulate drug delivery systems as well as their interaction with biological barriers.

Nicole Schneider-Daum studied Food Chemistry at the University of Kaiserslautern before doing her PhD at the German Cancer Research Center (DKFZ) in Heidelberg. She joined the institute of Biopharmaceutics and Pharmaceutical Technology at Saarland University in 2004 and started as senior scientist in the department “Drug Delivery” of the recently established Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) focusing on the establishment of new in vitro models of biological barriers.

Brigitta Loretz studied Microbiology at the University of Innsbruck. In April 2007 she received her PhD at the University of Innsbruck, Dep. of Pharmaceutical Technology for her work on novel strategies for oral gene delivery. As postdoc she joined Prof. Lehr’s group at the Saarland University in June 2007. After the foundation of the Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), shechanged to the new institute and is working there as senior scientist. Her research interests are nanocarriers for intracellular delivery of biopharmaceutics, with a special focus on biodegradable polymers.

Maike Windbergs studied Pharmacy in Düsseldorf. During her PhD in Pharmaceutics on novel biodegradable drug carriers, she spent research stays in Finland and the Netherlands. She performed a postdoctorate at Harvard University (USA) in the field of lab on a chip research, before joining Saarland University and the Helmholtz-Institute for Pharmaceutical Research Saarland as a senior scientist and habilitation candidate. Her research projects span from the design of innovative drug carriers and complex vitro models for skin absorption up to label-free Raman imaging.

Monday, 7 March 2016 – morning session

Non-Invasive Drug Delivery Across Epithelial Barriers

in cooperation with Controlled Release Society / CRS – Local Chapter Germany

Monday, 7 March 2016 – morning session

Non-Invasive Drug Delivery Across Epithelial Barriers

in cooperation with Controlled Release Society / CRS – Local Chapter Germany

Monday, 7 March 2016 – afternoon session

Advanced Nanocarriers for Overcoming Cellular Barriers (1)







Tuesday, 8 March 2016 – morning session

Probing and Shaping the Bio-Nano-Interface (1)

in cooperation with Galenus Foundation

Tuesday, 8 March 2016 – morning session

Probing and Shaping the Bio-Nano-Interface (2)

Tuesday, 8 March 2016 – afternoon session

Combating Infectious Diseases, Novel Approaches and in Vitro Models (1)

in cooperation with CAAT Europe


Combating Infectious Diseases, Novel Approaches and in vitro Models (2)

in cooperation with CAAT Europe

in vitro

in vitro

n vitro


Industry Session

Wednesday, 9 March 2016 – morning session

European Research Projects on Targeted Delivery to Biological Barriers (1)

ITN PathChooser – Innovative, Mechanistic-Based Strategies for Delivery of Therapeutic Macromolecules Across Cellular and Biological Barriers



ITN PathChooser – Innovative, Mechanistic-Based Strategies for Delivery of Therapeutic Macromolecules Across Cellular and Biological Barriers

ITN NABBA – Design and Development of Advanced NAnomedicines to Overcome Biological BArriersand to Treat Severe Diseases



IMI COMPACT – Collaboration on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets

Wednesday, 9 March 2016 – afternoon session

Workshop on GSP and Bibliometrics

We thank our partners and sponsors for providinginfrastructure, logistics, financial and professional support:

Documents

Saarland University, 7 – 9 March 2016 · 2016-03-04 · interests are the biopharmaceutical investigations of semisolid dosage forms for dermatological applications, the development