Scientific Commettee: Scientific Activity years 2008-2013

1. BIAVA Mariangela

G. POCE, G. ZAPPIA, G.C. PORRETTA, B. BOTTA, BIAVA M. (2008). New oxazolidinone derivatives as antibacterial agents with improved activity EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 18; p. 97-121, ISSN: 1354-3776, doi: 10.1517/13543776.18.2.97

CAPPELLI A, ANZINI M, BIAVA M., MAKOVEC F, GIORDANI A, CASELLI G, ROVATI LC (2008). Preparation of 3-substituted-1,5-diaryl-2-alkyl-pyrroles as highly selective and orally effective COX-2 inhibitors. WO 2006-EP65011. Rottapharm S.p.A.,

BIAVA M., CIRILLI R, FARES V, FERRETTI R, GALLINELLA B, LA TORRE F, POCE G, PORRETTA G.C., SUPINO S, VILLANI C. (2008). HPLC Enantioseparation and Absolute Configuration of Novel Antiinflammatory Pyrrole Derivatives. CHIRALITY, vol. 20; p. 775-780, ISSN: 0899-0042, doi: 10.1002/chir.20518

BIAVA M., PORRETTA GC, G. POCE, DE LOGU A, SADDI M, MELEDDU R, MANETTI F, DE ROSSI E, BOTTA M (2008). 1,5-Diphenyl Pyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 3644-3648, ISSN: 0022-2623, doi: 10.1021/jm701560p

ANZINI M, ROVINI M, CAPPELLI A, VOMERO S, MANETTI F, BOTTA M, SAUTEBIN L, ROSSI A, GHELARDINI C, NORCINI M, GIORDANI A, MAKOVEC F, ANZELLOTTI P, PATRIGNANI P, BIAVA M. (2008). Synthesis, Biological Evaluation, and Enzyme Docking Simulations of 1,5-Diarylpyrrole-3-Alkoxyethyl Ethers as Highly Selective COX-2 Inhibitors Endowed with Anti-inflammatory and Antinociceptive Activity. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 4476-4481, ISSN: 0022-2623, doi: 10.1021/jm800084s

BIAVA M., PORRETTA GC, POCE G, SUPINO S, MANETTI F, FORLI S, BOTTA M, SAUTEBIN L, ROSSI A, PERGOLA C, GHELARDINI C, NORCINI M, MAKOVEC F, ANZELLOTTI P, CIRILLI R, FERRETTI R, GALLINELLA B, LA TORRE F, ANZINI M, PATRIGNANI P (2008). Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16; p. 8072-8081, ISSN: 0968-0896, doi: 10.1016/j.bmc.2008.07.058

BIAVA M., PORRETTA GC, POCE G, DE LOGU A, SADDI M, MELEDDU R, MANETTI F, DE ROSSI E, BOTTA M (2009). 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 44; p. 4734-4738, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2009.06.005

BIAVA M., PORRETTA GC, POCE G, BATTILOCCHIO C, MANETTI F, BOTTA M, SAUTEBIN L, ROSSI A, PERGOLA C, GHELARDINI C, NORCINI M, MAKOVEC F, ANZELLOTTI P, CIRILLI R, FERRETTI R, PATRIGNANI P, ANZINI M (2010). Novel Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Anti-inflammatory and Analgesic Agents. Synthesis, in vitro and in vivo Biological Evaluation. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53; p. 723-733, ISSN: 0022-2623, doi: 10.1021/jm901269y

BIAVA M., PORRETTA GC, POCE G, BATTILOCCHIO C, ALFONSO S, DE LOGU A, SERRA N, MANETTI F, BOTTA M (2010). Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18; p. 8076-8084, ISSN: 0968-0896, doi: 10.1016/j.bmc.2010.09.006

BIAVA M., PORRETTA GC, POCE G, BATTILOCCHIO C, BOTTA M, MANETTI F, ROVINI M, CAPPELLI A, SAUTEBIN L, ROSSI A, PERGOLA C, GHELARDINI C, GALEOTTI N, MAKOVEC F, GIORDANI A, ANZELLOTTI P, TACCONELLI S, PATRIGNANI P, ANZINI M (2011). Enlarging the NSAIDs Family: Ether, Ester and Acid Derivatives of the 1,5-Diarylpyrrole Scaffold as Novel Anti-Inflammatory and Analgesic Agents. CURRENT MEDICINAL CHEMISTRY, vol. 18; p. 1540-1554, ISSN: 0929-8673

Maccari, G., Jaeger, T., Moraca, F, BIAVA M., Flohe, L, Botta, M. (2011). A fast virtual screening approach to identify structurally diverse inhibitors of trypanothione reductase. BIOORGANIC & MEDICINAL CHEMISTRY; p. 5255-5258, ISSN: 0968-0896

Schenone, S., Brullo, C., Musumeci, F., BIAVA M., Falchi, F., Botta, M. (2011). Fyn kinase in brain diseases and cancer: the search for inhibitors. . CURRENT MEDICINAL CHEMISTRY; p. 2921-2942, ISSN: 0929-8673

Radi, M., Brullo, C., Crespan, E., Tintori, C., Musumeci, F., BIAVA M., M., Schenone, S., Dreassi, E., Zamperini, C.., Maga, G., Pagano, D., Angelucci, A., Bologna, M., Botta, M. (2011). Identification of

potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; p. 5928-5933, ISSN: 0960-894X

BIAVA M., Porretta G. C., Poce G., Battilocchio, C., Alfonso, S., Rovini, M., Valenti, S., Giorgi, G., Calderone, V., Martelli, A., Testai, L., Sautebin, L., Rossi, A., Papa, G., Ghelardini, C., Di Cesare Mannelli, L., Giordani, A., Anzellotti, P., Bruno, A., Patrignani, P., Anzini (2011). Novel Analgesic/Anti-inflammatory Agents: Diarylpyrrole Acetic Esters Endowed with Nitric Oxide Releasing Properties,. JOURNAL OF MEDICINAL CHEMISTRY; p. 7750-7771, ISSN: 0022-2623, doi: 10.1021/jm200715n |

La Rosa, V., Poce, G., Ortiz Canseco, J., Buroni, S., Pasca, M.R., BIAVA M., M., Raju, R.M., Porretta, G.C., Alfonso, S., Battilocchio, C., Javid, B., Sorrentino, F., Ioerger, T.R., Sacchettini, J.C., Manetti, F., Botta, M., De Logu, A., Rubin, E.J. (2012). MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 56; p. 324-331, ISSN: 0066-4804, doi: 10.1128/AAC.05270-11

BIAVA M., PORRETTA GC, POCE G, BATTILOCCHIO C, ALFONSO S, DE LOGU A, MANETTI F, BOTTA M (2011). Developing Pyrrole-Derived Antimycobacterial Agents: a Rational Lead Optimization Approach. CHEMMEDCHEM, vol. 6(4); p. 593-599, ISSN: 1860-7179, doi: 10.1002/cmdc.201000526

Battilocchio, C., Baxendale, I.R., BIAVA M., M., Kitching, MO, Ley, S. V. (2012). Flow Based Synthesis of 2-aminoadamantane-2-carboxylic acid. ORGANIC PROCESS RESEARCH & DEVELOPMENT, vol. 16; p. 798-810, ISSN: 1083-6160, doi: 10.1021/op300084z

Battilocchio, Claudio, Baumann, Marcus, Baxendale, Ian R., BIAVA M., Kitching, Matthew O., Ley, Steven V., Martin, Rainer E., Ohnmacht, Stephan A., Tappin, Nicholas D. C. (2012). Scale-up of flow-assisted synthesis of C2-symmetric chiral PyBox ligands . SYNTHESIS; p. 635-647, ISSN: 0039-7881, doi: 10.1055/s-0031-1289676

Martelli A, Testai L, Anzini M, Cappelli A, Di Capua A, Biava M, Poce G, Consalvi S, Giordani A, Caselli G, Rovati L, Ghelardini C, Patrignani P, Sautebin L, Breschi MC, Calderone V. The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and endothelial dysfunction. Pharmacol Res. 2013 Sep 29;78C:1-9. doi: 10.1016/j.phrs.2013.09.008.

Fioravanti R, Desideri N, Biava M, Proietti Monaco L, Grammatica L, Yáñez M. Design, synthesis, and in vitro hMAO-B inhibitory evaluation of some 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazoles. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5128-30. doi: 10.1016/j.bmcl.2013.07.035.

Tintori C, Laurenzana I, La Rocca F, Falchi F, Carraro F, Ruiz A, Esté JA, Kissova M, Crespan E, Maga G, Biava M, Brullo C, Schenone S, Botta M. Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents. ChemMedChem. 2013 Aug;8(8):1353-60. doi: 10.1002/cmdc.201300204.

Baiocco P, Poce G, Alfonso S, Cocozza M, Porretta GC, Colotti G, Biava M, Moraca F, Botta M, Yardley V, Fiorillo A, Lantella A, Malatesta F, Ilari A. Inhibition of Leishmania infantum trypanothione reductase by azole-based compounds: a comparative analysis with its physiological substrate by X-ray crystallography. ChemMedChem. 2013 Jul;8(7):1175-83. doi: 10.1002/cmdc.201300176.

Battilocchio C, Poce G, Alfonso S, Porretta GC, Consalvi S, Sautebin L, Pace S, Rossi A, Ghelardini C, Di Cesare Mannelli L, Schenone S, Giordani A, Di Francesco L, Patrignani P, Biava M. A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity. Bioorg Med Chem. 2013 Jul 1;21(13):3695-701. doi: 10.1016/j.bmc.2013.04.031.

Friggeri L, Ballante F, Ragno R, Musmuca I, De Vita D, Manetti F, Biava M, Scipione L, Di Santo R, Costi R, Feroci M, Tortorella S. Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents. J Chem Inf Model. 2013 Jun 24;53(6):1463-74. doi: 10.1021/ci400132q.

Mazzarino M, Biava M, de la Torre X, Fiacco I, Botrè F.Characterization of the biotransformation pathways of clomiphene, tamoxifen and toremifene as assessed by LC-MS/(MS) following in vitro and excretion studies. Anal Bioanal Chem. 2013 Jun;405(16):5467-87. doi: 10.1007/s00216-013-6961-7.

Anzini M, Di Capua A, Valenti S, Brogi S, Rovini M, Giuliani G, Cappelli A, Vomero S, Chiasserini L, Sega A, Poce G, Giorgi G, Calderone V, Martelli A, Testai L, Sautebin L, Rossi A, Pace S, Ghelardini C, Di Cesare Mannelli L, Benetti V, Giordani A, Anzellotti P, Dovizio M, Patrignani P, Biava M. Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors. J Med Chem. 2013 Apr 25;56(8):3191-206. doi: 10.1021/jm301370e.

Sticozzi C, Belmonte G, Cervellati F, Di Capua A, Maioli E, Cappelli A, Giordani A, Biava M, Anzini M, Valacchi G. Antiproliferative effect of two novel COX-2 inhibitors on human keratinocytes. Eur J Pharm Sci. 2013 May 13;49(2):133-41. doi: 10.1016/j.ejps.2013.02.009.

Poce G, Bates RH, Alfonso S, Cocozza M, Porretta GC, Ballell L, Rullas J, Ortega F, De Logu A, Agus E, La Rosa V, Pasca MR, De Rossi E, Wae B, Franzblau SG, Manetti F, Botta M, Biava M. Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection. PLoS One. 2013;8(2):e56980. doi: 10.1371/journal.pone.0056980.

Desideri N, Fioravanti R, Proietti Monaco L, Biava M, Yáñez M, Ortuso F, Alcaro S. 1,5-Diphenylpenta-2,4-dien-1-ones as potent and selective monoamine oxidase-B inhibitors. Eur J Med Chem. 2013 Jan;59:91-100. doi: 10.1016/j.ejmech.2012.11.006.

2. BOLASCO Adriana

CHIMENTI F, FIORAVANTI R, BOLASCO A., MANNA F, CHIMENTI P, SECCI D, F. ROSSI, TURINI P, ORTUSO F, ALCARO S, CARDIA M.C (2008). Synthesis, molecular modeling studies and selective inhibitory activity against MAO of N1-propanoyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives. . EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 43; p. 2262-2267, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2007.12.026

FRANCO CHIMENTI, BRUNA BIZZARRI, ELIAS MACCIONI, DANIELA SECCI, BOLASCO A., PAOLA CHIMENTI, ROSSELLA FIORAVANTI, ARIANNA GRANESE, SIMONE CARRADORI, FEDERICA TOSI, PAOLA BALLARIO, S. VERNARECCI, PATRIZIA FILETICI (2009). A Novel Histone Acetyltransferase Inhibitor Modulating Gcn5 Network: Cyclopentylidene-[4-(4'-chlorophenyl)thiazol-2-yl)hydrazone. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52 (2); p. 530-536, ISSN: 0022-2623, doi: 10.1021/jm800885d

F.CHIMENTI, E.MACCIONI, D.SECCI, BOLASCO A., P.CHIMENTI, A.GRANESE, S.CARRADORI, S.ALCARO, F.ORTUSO, M.YANEZ, F.ORALLO, R.CIRILLI, R.FERRETTI, F.LA TORRE (2008). Synthesis, Stereochemical Identification, and Selective Inhibitory Activity against Human Monoamine Oxidase-B of 2-Methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51 (16); p. 4874-4880, ISSN: 0022-2623, doi: 10.1021/jm800132g

CHIMENTI, FRANCO, FIORAVANTI, ROSSELLA, BOLASCO A., ADRIANA, CHIMENTI, PAOLA, D. SECCI, DANIELA, ROSSI, FRANCESCA, YANEZ, MATILDE, ORALLO, FRANCISCO, ORTUSO, FRANCESCO, ALCARO, STEFANO, -. JMCMAR ISSN - (2009). Chalcones: A Valid Scaffold for Monoamine Oxidases Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52; p. 2818-2824, ISSN: 0022-2623, doi: 10.1021/jm801590u

CHIMENTI FRANCO, SECCI DANIELA, BOLASCO A., CHIMENTI PAOLA, BIZZARRI BRUNA, GRANESE ARIANNA, S. CARRADORI, YANEZ MATILDE, ORALLO FRANCISCO, ORTUSO FRANCESCO, ALCARO STEFANO (2009). Synthesis, Molecular Modeling, and Selective Inhibitory Activity against Human Monoamine Oxidases of 3-Carboxamido-7-Substituted Coumarins. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52 (7); p. 1935-1942, ISSN: 0022-2623, doi: 10.1021/jm801496u

F. CHIMENTI, B. BIZZARRI, BOLASCO A., D. SECCI, P. CHIMENTI, S. CARRADORI, A. GRANESE, D. RIVANERA, N. FRISHBERG, C. BORDÓN, L. JONES-BRANDO (2009). Synthesis and Evaluation of 4-Acyl-2- Thiazolylhydrazone Derivatives for anti-Toxoplasma Efficacy in Vitro. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52; p. 4574-4577, ISSN: 0022-2623, doi: 10.1021/jm9005862

F. CHIMENTI, S. CARRADORI, D. SECCI, BOLASCO A., P. CHIMENTI, A. GRANESE, B. BIZZARRI (2009). Synthesis and Biological Evaluation of Novel Conjugated Coumarin-Thiazole Systems. . JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 46; p. 575-578, ISSN: 0022-152X, doi: 10.1002/jhet.110

F. CHIMENTI, S. CARRADORI, D. SECCI, BOLASCO A., B. BIZZARRI, P. CHIMENTI, A. GRANESE, M. YANEZ, F. ORALLO (2010). Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 45; p. 800-804, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2009.11.003

CHIMENTI F, FIORAVANTI R, BOLASCO A., CHIMENTI P, SECCI D, F. ROSSI, YÁÑEZ M, ORALLO F, ORTUSO F, ALCARO S, CIRILLI R, FERRETTI R, SANNA M.L (2010). A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18; p. 1273-1279, ISSN: 0968-0896, doi: 10.1016/j.bmc.2009.12.029

CHIMENTI F, SECCI D, BOLASCO A., CHIMENTI P, GRANESE A, CARRADORI S, YANEZ M, ORALLO F, SANNA ML, GALLINELLA B, CIRILLI R (2010). SYNTHESIS, STEREOCHEMICAL SEPARATION, AND BIOLOGICAL EVALUATION OF SELECTIVE INHIBITORS OF HUMAN MAO-B: 1-(4-ARYLTHIAZOL-2-YL)-2-(3-METHYLCYCLOHEXYLIDENE)HYDRAZINES. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53; p. 6516-6520, ISSN: 0022-2623, doi: 10.1021/jm100120s

CHIMENTI F, SECCI D, BOLASCO A., CHIMENTI P, GRANESE A, CARRADORI S, D'ASCENZIO M, YANEZ M, ORALLO F (2010). Synthesis and selective inhibition of human monoamine oxidases of a large scaffold of (4,5-substituted-thiazol-2-yl)hydrazones From MedChemComm (2010), 1(1), 61-72. MEDCHEMCOMM, vol. 1; p. 61-72, ISSN: 2040-2503, doi: 10.1039/c0md00014k

CHIMENTI F, BOLASCO A., SECCI D, P. CHIMENTI, GRANESE A, CARRADORI S, YANEZ M, ORALLO F, ORTUSO F, ALCARO S (2010). Investigations on the 2-thiazolylhydrazyne scaffold: Synthesis and molecular modeling of selective human monoamine oxidase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 15; p. 5715-5723, ISSN: 0968-0896, doi: 10.1016/j.bmc.2010.06.007

F. CHIMENTI, SECCI D, BOLASCO A., CHIMENTI P, GRANESE A, CARRADORI S, MACCIONI E, CARDIA, MC, YANEZ M, ORALLO F, ALCARO S, ORTUSO F, CIRILLI R, FERRETTI R, DISTINTO S, KIRCHMAIR J, LANGER T (2010). Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY, vol. 18(14); p. 5063-5070, ISSN: 0968-0896, doi: 10.1016/j.bmc.2010.05.070

BOLASCO A., FIORAVANTI R, ROSSI, F, ROSSI P, VITALI A (2010). Use of cyclodextrins in biotransformation reactions with cell cultures of Morus nigra: biosynthesis of prenylated chalcone isocordoin From Biotechnology and Applied Biochemistry (2010), 56(2), 77-84. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, vol. 56; p. 77-84, ISSN: 0885-4513, doi: 10.1042/BA20100046

BOLASCO A., CARRADORI S, FIORAVANTI R (2010). Focusing on new monoamine oxidase inhibitors. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 20; p. 909-939, ISSN: 1354-3776, doi: 10.1517/13543776.2010.495716

N. DESIDERI, BOLASCO A., R. FIORAVANTI, L. PROIETTI MONACO, F. ORALLO, M. YANEZ, F. ORTUSO, S. ALCARO (2011). HOMOISOFLAVONOIDS: NATURAL SCAFFOLDS WITH POTENT AND SELECTIVE MONOAMINE OXIDASE-B INHIBITION PROPERTIES. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 2155-2164, ISSN: 0022-2623, doi: 10.1021/jm1013709

CHIMENTI F, BIZZARRI B, BOLASCO A., SECCI D, CHIMENTI P, GRANESE A, CARRADORI S, D'ASCENZIO M, D. LILLI, RIVANERA D (2011). Synthesis and biological evaluation of novel 2,4-disubstituted-1,3-thiazoles as anti-Candida spp. agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 46(1); p. 378-382, ISSN: 0223-5234

CHIMENTI F, BIZZARRI B, BOLASCO A., SECCI D, CHIMENTI P, GRANESE A, CARRADORI S, D'ASCENZIO M, SCALTRITO M M, SISTO F (2010). Synthesis and anti-Helicobacter pylori activity of 4-(coumarin-3-yl)thiazol-2-ylhydrazone derivatives. JOURNAL OF HETEROCYCLIC CHEMISTRY, vol. 47(6); p. 1269-1274, ISSN: 0022-152X, doi: 10.1002/jhet.464

R. FIORAVANTI, BOLASCO A., F.MANNA, F.ROSSI, F.ORALLO, M.YÁÑEZ, A.VITALI, F.ORTUSO, S.ALCARO, R.CIRILLI (2010). Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 45; p. 6135-6138, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2010.10.005

FIORAVANTI R, BOLASCO A., MANNA F, ROSSI F, ORALLO F, YANEZ M, VITALI A, ORTUSO F, ALCARO S (2010). Synthesis and molecular modelling studies of prenylated pyrazolines as MAO-B Inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20; p. 6479-6482, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2010.09.061

F. CHIMENTI, B. BIZZARRI, BOLASCO A., D. SECCI, P. CHIMENTI, A. GRANESE, S. CARRADORI, D. RIVANERA, A. ZICARI, M. M. SCALTRITO, F. SISTO (2010). Synthesis, selective anti-Helicobacter pylori activity, and cytotoxicity of novel N-substituted-2-oxo-2H-1-benzopyran-3-carboxamides. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. Aug (15) 20,16; p. 4922-4926, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2010.06.048

Daniela Secci, Simone Carradori, BOLASCO A., Paola Chimenti, Matilde Yáñez, Francesco Ortuso, Stefano Alcaro (2011). Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 46; p. 4846-4852, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2011.07.017

Roberto Cirilli, Stefano Alcaro, Rossella Fioravanti, Rosella Ferretti, BOLASCO A., Bruno Gallinella, Cristina Faggi (2011). A chromatographic study on the exceptional enantioselectivity of cellulose tris(4-methylbenzoate) towards C5-chiral 4,5-dihydro-(1H)-pyrazole derivatives. JOURNAL OF CHROMATOGRAPHY A, vol. 1218; p. 5653-5657, ISSN: 0021-9673, doi: 10.1016/j.chroma.2011.06.081

D. Secci, BOLASCO A., P. Chimenti and S. Carradori (2011). The State of the Art of Pyrazole Derivatives as Monoamine Oxidase Inhibitors and Antidepressant/Anticonvulsant Agents . CURRENT MEDICINAL CHEMISTRY, vol. 18; p. 5114-5144, ISSN: 0929-8673

F. Chimenti, B. Bizzarri, BOLASCO A., D. Secci, P. Chimenti, A. Granese, S. Carradori, M. D'Ascenzio, D. Lilli, D. Rivanera (2011). Synthesis and biological evaluation of novel 2,4-disubstituted-1,3-thiazoles as anti-Candida spp. agents. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 46; p. 378-382, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2010.10.027

D. Trisciuoglio, Y. Ragazzoni, A. Pelosi, M. Desideri, S. Carradori, C. Gabellini, G. Maresca, R. Nescatelli, D. Secci, BOLASCO A., B. Bizzarri, C. Cavaliere, I. D'Agnano, P. Filetici, L. Ricci-Vitiani, M.G. Rizzo, D. Del Bufalo (2012). CPTH6, a thiazole-derivative, induces histone hypoacetylation and apoptosis in human leukemia cells. CLINICAL CANCER RESEARCH, vol. 18; p. 475-486, ISSN: 1078-0432, doi: 10.1158/1078-0432.CCR-11-0579

Secci D., BOLASCO A., D’Ascenzio M., della Sala F., Yáñez M., Carradori S. (2012). Conventional and Microwave-Assisted Synthesis of Benzimidazole Derivatives and their in vitro Inhibition of human Cyclooxygenase. . JOURNAL OF HETEROCYCLIC CHEMISTRY, ISSN: 0022-152X, doi: 10.1002/jhet

Alcaro, Stefano, BOLASCO A., Adriana, Cirilli, Roberto, Ferretti, Rossella, Fioravanti, Rossella, Ortuso, Francesco (2012). Computer-aided molecular design of asymmetric pyrazole derivatives with exceptional enantioselective recognition towards the Chiralcel OJ-H stationary phase. . JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 52; p. 649-654, ISSN: 1549-9596, doi: 10.1021/ci200592h

Secci D., Bizzarri B., BOLASCO A., Carradori S., D'Ascenzio M, Rivanera D., Mari E., Polletta L., Zicari A. (2012). Synthesis, anti-Candida activity, and cytotoxicity of new (4-(4-iodophenyl)thiazol-2-yl)hydrazine derivatives . EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 53; p. 246-253, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2012.04.006

Distinto S, Yáñez M, Alcaro S, Cardia M.C, Gaspari M, Sanna M.L, Meleddu R, Ortuso F, Kirchmair J, Markt P, BOLASCO A., Wolber G, Secci D, Maccioni E. (2012). Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 48; p. 284-295, ISSN: 0223-5234

Carradori S., Secci D., BOLASCO A., Chimenti P., D'Ascenzio M. (2012). Patent-related survey on new monoamine oxidase inhibitors and their therapeutic potential. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 22; p. 759-801, ISSN: 1354-3776, doi: 10.1517/13543776.2012.698613

Carradori S, Secci D, Bolasco A, Rivanera D, Mari E, Zicari A, Lotti LV, Bizzarri B. Synthesis and cytotoxicity of novel (thiazol-2-yl)hydrazine derivatives as promising anti-Candida agents. Eur J Med Chem. 2013 Jul;65:102-11. doi: 10.1016/j.ejmech.2013.04.042.

3. BOTTA Bruno

G. POCE, G. ZAPPIA, G.C. PORRETTA, BOTTA B., M. BIAVA (2008). New oxazolidinone derivatives as antibacterial agents with improved activity EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 18; p. 97-121, ISSN: 1354-3776, doi: 10.1517/13543776.18.2.97

BOTTA B., M. PIERINI, G. DELLE MONACHE, D. SUBISSATI, F. SUBRIZI, G. ZAPPIA (2008). Synthesis of amino and ammonium resorcin[4]arenes as potential receptors. SYNTHESIS, vol. 13; p. 2110-2116, ISSN: 0039-7881, doi: 10.1055/s-2008-1067111

M. SPERANZA, F. GASPARRINI, BOTTA B., C. VILLANI, D. SUBISSATI, C. FRASCHETTI, F. SUBRIZI (2009). Gas-phase enantioselective reactions in noncovalent ion-molecule complexes . CHIRALITY, vol. 21; p. 69-86, ISSN: 0899-0042, doi: 10.1002/chir.20606

ILARI A, FRANCESCHINI S, A. BONAMORE, ARENGHI F, BOTTA B., MACONE A, PASQUO A, BELLUCCI L, BOFFI A (2009). Structural basis of enzymatic (S)-norcoclaurine biosynthesis. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 284(2); p. 897-904, ISSN: 0021-9258, doi: 10.1074/jbc.M803738200

BOTTA B., FRASCHETTI C, NOVARA F. R, TAFI A, SACCO F, MANNINA L, SOBOLEV A. P, MATTAY J, LETZEL M. C, M. SPERANZA (2009). Interactions of vinca alkaloid subunits with chiral amido[4]resorcinarenes: a dynamic, kinetic, and spectroscopic study. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 7; p. 1798-1806, ISSN: 1477-0520, doi: 10.1039/b900735k

M. SPERANZA, D'ACQUARICA I, FRASCHETTI C, BOTTA B., TAFI A, BELLUCCI L, ZAPPIA G (2010). Diastereoselective gas-phase ion/molecule reactions of ethanolamine neurotransmitter/amido[4]resorcinarene adducts. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, vol. 291; p. 84-89, ISSN: 1387-3806, doi: 10.1016/j.ijms.2010.01.017

BONAMORE A, BARBA M, BOTTA B., A. BOFFI, MACONE M (2010). Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme. MOLECULES, vol. 15; p. 2070-2078, ISSN: 1420-3049, doi: 10.3390/molecules15042070

A. MACONE, FONTANA M, BARBA M, BOTTA B., NARDINI M, GHIRGA F, CALCATERRA A, PECCI L, MATARESE RM (2011). Antioxidant Properties of Aminoethylcysteine Ketimine Decarboxylated Dimer: A Review. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 12(5); p. 3072-3084, ISSN: 1422-0067, doi: 10.3390/ijms12053072

BONAMORE A, ROVARDI I, GASPARRINI F, BAIOCCO P, BARBA M, MOLINARO C, BOTTA B., BOFFI A, A. MACONE (2010). An enzymatic, stereoselective synthesis of (S)-norcoclaurine. GREEN CHEMISTRY, vol. 12; p. 1623-1627, ISSN: 1463-9262, doi: 10.1039/c0gc00036a

BOTTA B., FRASCHETTI C, D'ACQUARICA I, SACCO F, MATTAY J, LETZEL M. C, M. SPERANZA (2011). Unprecedented gas-phase chiroselective logic gates. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9; p. 1717-1719, ISSN: 1477-0520, doi: 10.1039/C0OB00664E

I. D'ACQUARICA, A. CERRETO, G. DELLE MONACHE, F. SUBRIZI, A. BOFFI, A. TAFI, S. FORLI, BOTTA B. (2011). N-Linked peptidoresorc[4]arene-based receptors as noncompetitive inhibitors for a-chymotrypsin. JOURNAL OF ORGANIC CHEMISTRY, vol. 76; p. 4396-4407, ISSN: 0022-3263, doi: 10.1021/jo102592f

A. FILIPPI, C. FRASCHETTI, S. PICCIRILLO, F. RONDINO, BOTTA B., I. D’ACQUARICA, A. CALCATERRA, M. SPERANZA (2012). Chirality effects on the IRMPD spectra of basket resorcinarene/nucleoside complexed. CHEMISTRY-A EUROPEAN JOURNAL, vol. 18; p. 8320-8328, ISSN: 0947-6539, doi: 10.1002/chem.201200614

Mascarello A, Mori M, Chiaradia-Delatorre LD, Menegatti AC, Monache FD, Ferrari F, Yunes RA, Nunes RJ, Terenzi H, Botta B, Botta M. Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products. PLoS One. 2013 Oct 14;8(10):e77081. doi: 10.1371/journal.pone.0077081.

D'Acquarica I, Calcaterra A, Sacco F, Balzano F, Aiello F, Tafi A, Pesci N, Uccello-Barretta G, Botta B. Stereochemical Preference of 2'-Deoxycytidine for Chiral Bis(diamido)-bridged Basket Resorcin[4]arenes. Chirality. 2013 Aug 28. doi: 10.1002/chir.22224.

Ghirga F, D'Acquarica I, Delle Monache G, Mannina L, Molinaro C, Nevola L, Sobolev AP, Pierini M, Botta B. Reaction of nitrosonium cation with resorc[4]arenes activated by supramolecular control: covalent bond formation. J Org Chem. 2013 Jul 19;78(14):6935-46. doi: 10.1021/jo400489m.

4. CARAFA Maria

S. SENNATO, F. BORDI, C. CAMETTI, C. MARIANECCI, CARAFA M., M. CAMETTI (2008). Hybrid niosome complexation in the presence of oppositely charged polyions. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 112(12); p. 3720-3727, ISSN: 1520-6106, doi: 10.1021/jp0775449

G CARACCIOLO, D POZZI, R CAMINITI, C MARIANECCI, S MOGLIONI, CARAFA M., H AMENITSCH (2008). Effect of hydration on the structure of solid-supported Niosomal membranes investigated by in situ energy dispersive X-ray diffraction. CHEMICAL PHYSICS LETTERS, vol. 462; p. 307-312, ISSN: 0009-2614, doi: 10.1016/j.cplett.2008.07.094

DI MARZIO L, MARIANECCI C, CINQUE B, NAZZARRI M, CIMINI AM, CRISTIANO L, CIFONE MG, ALHAIQUE F, CARAFA M. (2008). pH-sensitive non-phospholipid vesicle and macrophage-like cells: Binding, uptake and endocytotic pathway. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, vol. 1778; p. 2749-2756, ISSN: 0005-2736, doi: 10.1016/j.bbamem.2008.07.029

CARAFA M., C. MARIANECCI, F. RINALDI, E. SANTUCCI, S. TAMPUCCI, D. MONTI (2009). Span® and Tween® neutral and pH-sensitive vesicles: characterization and in vitro skin permeation. JOURNAL OF LIPOSOME RESEARCH, vol. 19; p. 332-340, ISSN: 0898-2104, doi: 10.3109/08982100903014994

POZZI D, CAMINITI R, MARIANECCI C, CARAFA M., SANTUCCI E, M. CANDELORO, CARACCIOLO G (2010). Effect of Cholesterol on the Formation and Hydration Behaviour of Solid-Supported Niosomal Membranes . LANGMUIR, vol. 26 (4); p. 2268-2273, ISSN: 0743-7463, doi: 10.1021/la9026877

CARAFA M., C. MARIANECCI, L. DI MARZIO, V. DE CARO, G. GIANDALIA, L. I. GIANNOLA, E. SANTUCCI (2010). Potential dopamine prodrug-loaded liposomes: preparation, characterization, and in vitro stability studies. JOURNAL OF LIPOSOME RESEARCH, vol. 20; p. 250-257, ISSN: 0898-2104, doi: 10.3109/08982100903384129

MASOTTI A, VICENNATI P, ALISI A, MARIANECCI C, RINALDI F, CARAFA M., G. ORTAGGI (2010). Novel Tween (R) 20 derivatives enable the formation of efficient pH-sensitive drug delivery vehicles for human hepatoblastoma. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20; p. 3021-3025, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2010.04.010

D. POZZI, MARIANECCI C, CARAFA M., MARCHINI C, MONTANI M, AMICI A, CARACCIOLO G (2010). Programmed Packaging of Multicomponent Envelope-type Nanoparticle System for Gene Delivery. APPLIED PHYSICS LETTERS, vol. 96; p. 183702-1-183702-3, ISSN: 0003-6951, doi: 10.1063/1.3427354

CARAFA M., FRANCO ALHAIQUE, CARLOTTA MARIANECCI, DONATELLA PAOLINO, MASSIMO FRESTA (2010). Niosomi, polvere liofilizzata di essi e loro uso in terapia . RM2010A000002. Università di Roma "Sapienza" e Università di Catanzaro "Magna Grecia"

C. MARIANECCI, D. PAOLINO, C. CELIA, M. FRESTA, CARAFA M., F. ALHAIQUE (2010). Non-ionic surfactant Vesicles in Pulmonary Glucocorticoid Delivery: Characterization and Interaction with Human Lung Fibroblasts. JOURNAL OF CONTROLLED RELEASE, vol. 147; p. 127-135, ISSN: 0168-3659, doi: 10.1016/j.jconrel.2010.06.022

CHIARA AGRATI, CARLOTTA MARIANECCI, SIMONA SENNATO, CARAFA M., VERONICA BORDONI, ELEONORA CIMINI, MASSIMO TEMPESTILLI, LEOPOLDO P. PUPILLO, FEDERICA TURCHI, FEDERICO MARTINI, GIORGIO BORIONI, F. BORDI (2011). Multicompartment vectors as novel drug delivery systems: selective activation of T¿d lymphocytes after zoledronic acid delivery. NANOMEDICINE, vol. 7; p. 153-161, ISSN: 1549-9634, doi: 10.1016/j.nano.2010.10.003

Marianecci C, CARAFA M., Di Marzio L, Rinaldi F, Di Meo C, Matricardi P, Alhaique F, Coviello T (2011). A New Vesicle-loaded Hydrogel System Suitable for Topical Applications: Preparation and Characterization. JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES, vol. 14; p. 336-346, ISSN: 1482-1826

CARAFA M., C. MARIANECCI, SALVATORELLI M, DI MARZIO L, CERRETO F, LUCANIA G, SANTUCCI E (2008). FORMULATIONS OF RETINYL PALMITATE INCLUDED IN SOLID LIPID NANOPARTICLES: CHARACTERIZATION AND INFLUENCE ON LIGHT-INDUCED VITAMIN DEGRADATION. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, vol. 18; p. 119-124, ISSN: 1773-2247

CARAFA M., Carlotta Marianecci, Paolino Donatella, Luisa Di Marzio, Christian Celia, Massimo Fresta, Franco Alhaique (2012). Novel concept in pulmonary delivery. In: Kian-Chung Ong . Chronic Obstructive Pulmonary Disease - Current Concepts and Practice. p. 299-332, InTech - Open Access Publisher , ISBN/ISSN: 9799533070383

G. CARACCIOLO, D. POZZI, A.L. CAPRIOTTI, C. MARIANECCI, CARAFA M., C. MARCHINI, M. MONTANI, A. AMICI, H. AMENITSCH, M.A. DIGMAN, E. GRATTON, S.S. SANCHEZ, A. LAGANA' (2011). Factors Determining the Superior Performance of Lipid/DNA/Protammine Nanoparticles over Lipoplexes. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 4160-4171, ISSN: 0022-2623, doi: 10.1021/jm200237p

Carlotta Marianecci, Luisa Di Marzio, Federica Rinaldi, CARAFA M., Franco Alhaique (2011). Pulmonary delivery: innovative approaches and perspectives. JOURNAL OF BIOMATERIALS AND NANOBIOTECHNOLOGY, vol. 2; p. 567-575, ISSN: 2158-7027, doi: 10.4236/jbnb.2011.225068

D. POZZI, R. CAMINITI, G. CARACCIOLO, C. MARIANECCI, CARAFA M., E. SANTUCCI (2009). Effect of cholesterol on the structure of phospholipids and non-phospholipid membranes. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, vol. 38; p. S193-S193, ISSN: 0175-7571, doi: 10.1007/s00249-009-0478-1

DANIELA POZZI, CARLOTTA MARIANECCI, CARAFA M., CRISTINA MARCHINI, MAURA MONTANI, AUGUSTO AMICI, G. CARACCIOLO (2010). Programmed packaging of multicomponent envelope-type nanoparticle system (MENS). JOURNAL OF CONTROLLED RELEASE, vol. 148; p. 87-89, ISSN: 0168-3659, doi: 10.1016/j.jconrel.2010.07.063

CARAFA M., FRANCO ALHAIQUE, C. MARIANECCI, DONATELLA PAOLINO, MASSIMO FRESTA (2011). “NIOSOMES, LYOPHILIZED POWDER THEREOF AND THEIR USES IN THERAPY”. WO2011083428. Università di Roma Sapienza, Università Magna Grecia

Luisa Di Marzio, Carlotta Marianecci, Federica Rinaldi, Sara Esposito, CARAFA M. (2012). Deformable surfactant vesicles loading ammonium glycyrrhizinate: characterization and in vitro permeation studies. LETTERS IN DRUG DESIGN & DISCOVERY, vol. 5; p. 1-6, ISSN: 1570-1808, doi: 10.2174/157018012800389287

LUISA DI MARZIO, CARLOTTA MARIANECCI, MARIADEA PETRONE, FEDERICA RINALDI, CARAFA M. (2011). Novel pH-sensitive non-ionic surfactant vesicles: comparison between Tween 21 and Tween 20. COLLOIDS AND SURFACES. B, BIOINTERFACES, vol. 82; p. 18-24, ISSN: 0927-7765, doi: 10.1016/j.colsurfb.2010.08.004

Carlotta Marianecci, Federica Rinaldi, Marica Mastriota, Stefano Pieretti, Elena Trapasso, Donatella Paolino, CARAFA M. (in stampa). Anti-inflammatory activity of novel ammonium glycyrrhizinate/niosomes delivery system: human and murine models. JOURNAL OF CONTROLLED RELEASE, ISSN: 0168-3659, doi: 10.1016/j.jconrel.2012.09.018

Celia C, Trapasso E, Locatelli M, Navarra M, Ventura CA, Wolfram J, Carafa M, Morittu VM, Britti D, Di Marzio L, Paolino D. Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells. Colloids Surf B Biointerfaces. 2013 Dec 1;112:548-53. doi: 10.1016/j.colsurfb.2013.09.017.

Molinaro R, Wolfram J, Federico C, Cilurzo F, Di Marzio L, Ventura CA, Carafa M, Celia C, Fresta M. Polyethylenimine and chitosan carriers for the delivery of RNA interference effectors. Expert Opin Drug Deliv. 2013 Oct 4.

Ansari SA, Matricardi P, Cencetti C, Di Meo C, Carafa M, Mazzuca C, Palleschi A, Capitani D, Alhaique F, Coviello T. Sonication-based improvement of the physicochemical properties of Guar Gum as a potential substrate for modified drug delivery systems. Biomed Res Int. 2013;2013:985259. doi: 10.1155/2013/985259.

Marianecci C, Rinaldi F, Esposito S, Di Marzio L, Carafa M. Niosomes encapsulating Ibuprofen-cyclodextrin complexes: preparation and characterization. Curr Drug Targets. 2013 Aug;14(9):1070-8.

Di Marzio L, Esposito S, Rinaldi F, Marianecci C, Carafa M. Polysorbate 20 vesicles as oral delivery system: in vitro characterization. Colloids Surf B Biointerfaces. 2013 Apr 1;104:200-6. doi: 10.1016/j.colsurfb.2012.10.036. Epub 2012 Dec 20.

Marianecci C, Rinaldi F, Di Marzio L, Pozzi D, Caracciolo G, Manno D, Dini L, Paolino D, Celia C, Carafa M. Interaction of pH-sensitive non-phospholipid liposomes with cellular mimetic membranes. Biomed Microdevices. 2013 Apr;15(2):299-309. doi: 10.1007/s10544-012-9731-y.

5. CASADEI Maria Antonietta

CASADEI M., PITARRESI G., CALABRESE R., PAOLICELLI P., GIAMMONA G. (2008). Biodegradable and pH-sensitive hydrogels for potential colon-specific drug delivery: characterization and in vitro release studies. BIOMACROMOLECULES, vol. 9; p. 43-49, ISSN: 1525-7797, doi: 10.1021/bm700716c

PAOLICELLI P, CERRETO F, CESA S, FEENEY M, CORRENTE F, MARIANECCI C, CASADEI M. (2009). Influence of the formulation components on the properties of the system SLN-dextran hydrogel for the modified release of drugs. JOURNAL OF MICROENCAPSULATION, vol. 26; p. 355-364, ISSN: 0265-2048, doi: 10.1080/02652040802372899

MATRICARDI P, PONTORIERO M, COVIELLO T, CASADEI M., ALHAIQUE F (2008). In situ cross-linkable novel alginate-dextran methacrylate IPN hydrogels for biomedical applications. Mechanical characterization and drug delivery properties. BIOMACROMOLECULES, vol. 9; p. 2014-2020, ISSN: 1525-7797, doi: 10.1021/bm800252c

GIANNUZZO M, CORRENTE F, FEENEY M, PAOLETTI L, PAOLICELLI P, TITA B, VITALI F, CASADEI M. (2008). pH-sensitive hydrogels of dextran: synthesis, characterization and in vivo studies. JOURNAL OF DRUG TARGETING, vol. 16; p. 649-659, ISSN: 1061-186X, doi: 10.1080/10611860802201191

FEENEY M, CASADEI M., MATRICARDI P (2009). Carboxymethyl derivative of scleroglucan: a novel thermosensitive hydrogel forming polysaccharide for drug delivery applications. JOURNAL OF MATERIALS SCIENCE. MATERIALS IN MEDICINE, vol. 20; p. 1081-1087, ISSN: 0957-4530, doi: 10.1007/s10856-008-3665-1

SCALZO M, STRATI M, CASADEI M., CERRETO F, CESA S (2009). Colorimetric investigation of the reaction between p-phenylendiamine and meta-substituted derivatives of benzene on a model support . JOURNAL OF COSMETIC SCIENCE, vol. 60; p. 429-436, ISSN: 1525-7886

CORRENTE F, MATRICARDI P, PAOLICELLI P, TITA B, VITALI F, CASADEI M. (2009). Physical Carboxymethylscleroglucan/Calcium Ion Hydrogels as Modified Drug Delivery Systems in Topical Formulations. MOLECULES, vol. 14; p. 2684-2698, ISSN: 1420-3049, doi: 10.3390/molecules14082684

CORRENTE F, MATRICARDI P, PAOLICELLI P, CASADEI M. (2009). pH-sensitive hydrogels for the controlled release of anti-inflammatory drugs. In: Atti. Copenhagen, Denmark, 18-22 luglio 2009, vol. 1, p. 367-368

CORRENTE F, PAOLICELLI P, CASADEI M. (2009). The system SLN-hydrogel of dextran for the modified release of ketoconazole. In: Atti. Cagliari, 10-13 settembre 2009, p. 123-123

CASADEI M., CORRENTE F, PAOLICELLI P (2010). Preparation and characterization of hydrogel microparticles obtained in w/o emulsion. In: Atti. La Valletta, Malta, 8-11 Marzo 2010, p. 78-78

F. CORRENTE, P. PAOLICELLI, V. POCHINI, CASADEI M. (2010). Novel polysaccharidic hydrogels for tissue engineering: synthesis and characterization. In: Atti. La Valletta, Malta, 8-11 Marzo 2010, p. 44-44

CESA S, CASADEI M., CERRETO F, CORRENTE F (2008). Nanoparticelle solide lipidiche come sistema protettivo nei confronti dell’autossidazione lipidica. In: ATTI VI CONGRESSO NAZIONALE DI CHIMICA DEGLI ALIMENTI PERUGIA 2008. Perugia, 23-26 Giugno 2008, vol. Atti, p. 9-9

PITARRESI G, CASADEI M., MANDRACCHIA D, PAOLICELLI P, PALUMBO F.S, GIAMMONA G (2007). Photocrosslinking of dextran and polyaspartamide derivatives: a combination suitable for colon-specific drug delivery. JOURNAL OF CONTROLLED RELEASE, vol. 119; p. 328-338, ISSN: 0168-3659, doi: 10.1016/j.jconrel.2007.03.005

Cesa S., Paolicelli P., Cerreto F., CASADEI M. (2012). Comparison between third derivative spectrophotometric method and hplc-dad method in detection of malondialdehyde in infant formulae, human and cow milks. JOURNAL OF CHEMICAL AND PHARMACEUTICAL RESEARCH, vol. 4; p. 221-230, ISSN: 0975-7384

Paolicelli P., Corrente F., Serricchio D., Cerreto F., Cesa S., Tita B., Vitali F., D'Auria F.D., Simonetti G., CASADEI M. (2011). The system sln-dextran hydrogel: an application for the topical release of ketoconazole. JOURNAL OF CHEMICAL AND PHARMACEUTICAL RESEARCH, vol. 3; p. 410-421, ISSN: 0975-7384

Cerreto F., Scalzo M., Cesa S., Paolicelli P., CASADEI M. (2011). Solid lipid nanoparticles based on low melting lipids as protective system of retinyl palmitate. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, vol. 21; p. 479-483, ISSN: 1773-2247

CORRENTE F, PAOLICELLI P, MATRICARDI P, TITA B, VITALI F, CASADEI M. (2012). Novel pH-sensitive physical hydrogels of carboxymethyl scleroglucan. JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 101; p. 256-267, ISSN: 0022-3549

Paolicelli P., CASADEI M., Lopez Cebral R., Sejio Rei B., Sanchez Barreiro A. (2010). Hidrogeles elaborados a base de polimeros anionicos de origen natural. P 201030624

PAOLICELLI P, CESA S, CERRETO F, CORRENTE F, SERRICCHIO D, CASADEI M. (2010). Perspectives and challenges of the SLN technology: from drug to food. In: Collection of abstracts presented at 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. La Valletta, Malta, 8-11 March 2010, p. 78-78

S. Cacchi, E. Caponetti, CASADEI M., A. Di Giulio, G.Fabrizi, G. Forte, A. Goggiamani, S. Moreno, P. Paolicelli, F. Petrucci, A. Prastaro M. L. Saladino (2012). Suzuki-Miyaura cross-coupling of arenediazonium salts catalyzed by alginate/gellan-stabilized palladium nanoparticles under aerobic conditions in water. GREEN CHEMISTRY, vol. 14; p. 317-320, ISSN: 1463-9262, doi: 10.1039/c2gc15679b

Iodice G, Bocchino T, Casadei M, Baldi D, Robiony M. Evaluations of sagittal and vertical changes induced by surgically assisted rapid palatal expansion. J Craniofac Surg. 2013 Jul;24(4):1210-4. doi: 10.1097/SCS.0b013e3182997830.

López-Cebral R, Paolicelli P, Romero-Caamaño V, Seijo B, Casadei MA, Sanchez A. Spermidine-cross-linked hydrogels as novel potential platforms for pharmaceutical applications. J Pharm Sci. 2013 Aug;102(8):2632-43. doi: 10.1002/jps.23631.

Cerreto F, Paolicelli P, Cesa S, Abu Amara HM, D'Auria FD, Simonetti G, Casadei MA. Solid lipid nanoparticles as effective reservoir systems for long-term preservation of multidose formulations. AAPS PharmSciTech. 2013 Jun;14(2):847-53. doi: 10.1208/s12249-013-9972-y

Corrente F, Abu Amara HM, Pacelli S, Paolicelli P, Casadei MA. Novel injectable and in situ cross-linkable hydrogels of dextran methacrylate and scleroglucan derivatives: preparation and characterization. Carbohydr Polym. 2013 Feb 15;92(2):1033-9. doi: 10.1016/j.carbpol.2012.10.018.

6. COVIELLO Tommasina

SANDOLO C, MATRICARDI P, F. ALHAIQUE, COVIELLO T. (2009). Effect of temperature and cross-linking density on rheology of chemical cross-linked guar gum at the gel point. FOOD HYDROCOLLOIDS, vol. 23; p. 210-220, ISSN: 0268-005X, doi: 10.1016/j.foodhyd.2008.01.001

MATRICARDI P, DI MEO C, COVIELLO T., F. ALHAIQUE (2008). Recent advances and perspectives on coated alginate microspheres for modified drug delivery. EXPERT OPINION ON DRUG DELIVERY, vol. 5; p. 417-425, ISSN: 1742-5247, doi: 10.1517/17425247.5.4.417

BOCCHINFUSO G, PALLESCHI A, MAZZUCA C, COVIELLO T., ALHAIQUE F, MARLETTA G (2008). Theoretical and experimental study on a self-assembling polysaccharide forming nanochannels: static and dynamic effects induced by a soft confinement. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 112; p. 6473-6483, ISSN: 1520-6106, doi: 10.1021/jp076074f

COVIELLO T., MATRICARDI P, SANDOLO C, DI MEO C, ALHAIQUE F (2008). Physical and chemical gels for modified drug delivery: a dynamo-mechanical and rheological characterization . In: 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. Barcelona, Spain, April 7-10, vol. 6, p. 37-

MATRICARDI P, MASCI G, COVIELLO T., PESCOSOLIDO L, DI MEO C, ALHAIQUE F (2008). NEW SURFACE-COATED ALGINATE MICROSPHERES SHOWING THERMO-SENSITIVE AND

LIPOPHYLIC PROPERTIES SUITABLE FOR MODIFIED DRUG DELIVERY. In: -. Barcellona, Spain, 7-10 aprile 2008, vol. 6, p. 18-

MATRICARDI P, MASCI G, COVIELLO T., ALHAIQUE F (2007). Thermo-sensitive Smart Alginate Microspheres: A Novel Hydrogel System Suitable For Modified Drug Release. In: -. Viareggio, 14-18 novembre 2007, p. 38-38

COVIELLO T., C. SANDOLO, G. BOCCHINFUSO, C. DI MEO, P. MATRICARDI, A. PALLESCHI, F. ALHAIQUE (2008). Polysaccharide hydrogels: modelling and mechanical characterization. In: 48° Simposio AFI. Rimini (Italy), June 11-13, vol. 48, p. 184-184

COVIELLO T., SANDOLO C, BOCCHINFUSO G, DI MEO C, MATRICARDI P, PALLESCHI A, ALHAIQUE F (2008). Mechanical and modelling characterization of polysaccharidic hydrogels for modified drug delivery. In: PNG2008, 19th Polymer Networks Group Meeting. Larnaca, Cyprus, June 22-26, vol. 19, p. 143-143

M. GRASSI, R. LAPASIN, COVIELLO T., P. MATRICARDI, F. ALHAIQUE (2008). Gel di scleroglucano-borace per il rilascio modificato di principi attivi. In: Convegno GR.I.C.U. 2008, Ingegneria Chimica: le nuove sfide. LE CASTELLA (KR) (Italy, September 14-17, vol. 1, p. 87-92

COVIELLO T., BERTOLO L, MATRICARDI P, PALLESCHI A, BOCCHINFUSO G, MARAS A, ALHAIQUE F (2009). Peculiar behavior of polysaccharide/borax hydrogel tablets: a dynamomechanical characterization . COLLOID AND POLYMER SCIENCE, vol. 287; p. 413-423, ISSN: 0303-402X, doi: 10.1007/s00396-008-1980-1

PESCOSOLIDO L, MIATTO S, DI MEO C, CENCETTI C, COVIELLO T., ALHAIQUE F, MATRICARDI P (2010). Injectable and in situ gelling hydrogels for modified protein release . EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, vol. 39; p. 903-909, ISSN: 0175-7571, doi: 10.1007/s00249-009-0440-2

GRASSI M, LAPASIN R, COVIELLO T., MATRICARDI P, DI MEO C, ALHAIQUE F (2009). Scleroglucan/borax/drug hydrogels: structure characterisation by means of rheological and diffusion experiments. CARBOHYDRATE POLYMERS, vol. 78; p. 377-383, ISSN: 0144-8617, doi: 10.1016/j.carbpol.2009.04.025

SANDOLO C, MARGHERITELLI S, ALHAIQUE F, MATRICARDI P, COVIELLO T. (2009). Preparation and Characterization of Physical and Chemical Polysaccharidic Hydrogels for Modified Drug Delivery. In: -. Nice (France), June 7-8, 2009

GRASSI M, SANDOLO C, PERIN D, COVIELLO T., LAPASIN R, GRASSI G (2009). Structural characterization of calcium alginate matrices by means of mechanical and release tests. MOLECULES, vol. 14; p. 3003-3017, ISSN: 1420-3049, doi: 10.3390/molecules14083003

COVIELLO T., MATRICARDI P, BALENA A, CHIAPPERINO B, ALHAIQUE F (2010). Hydrogels from scleroglucan and ionic crosslinkers: characterization and drug delivery. JOURNAL OF APPLIED POLYMER SCIENCE, vol. 115; p. 3610-3622, ISSN: 0021-8995, doi: 10.1002/app.31375

COVIELLO T., P. MATRICARDI, C. DI MEO, C. SANDOLO, S. MARGHERITELLI, F. ALHAIQUE (2009). Characterization and drug delivery studies on new hydrogels from Scleroglucan and ionic cross-linkers. In: 36th Annual Meeting & Exposition of the Controlled Release Society. Copenhagen, Denmark, July 18-22, vol. 36, p. 525-

MATRICARDI P, CENCETTI C, RIA R, ALHAIQUE F, COVIELLO T. (2009). Preparation and characterization of novel Gellan gum hydrogels suitable for modified drug release. MOLECULES, vol. 14; p. 3376-3391, ISSN: 1420-3049, doi: 10.3390/molecules14093376

ODDO L, MASCI G, DI MEO C, CAPITANI D, MANNINA L, LAMANNA R, DE SANTIS S, ALHAIQUE F, COVIELLO T., MATRICARDI P (2010). Novel thermo-sensitive calcium alginate microspheres: Physico-chemical characaterization and delivery properties. ACTA BIOMATERIALIA, vol. 6; p. 3657-3664, ISSN: 1742-7061, doi: 10.1016/j.actbio.2010.03.013

COVIELLO T., C. SANDOLO, P. MATRICARDI, C. DI MEO, F. ALHAIQUE (2010). Rheological characterization of hydrogel systems for biomedical applications. In: 7th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. Valletta, Malta, March 8-11, vol. VII, p. 115-116

PESCOSOLIDO L, CENCETTI C, MATRICARDI P, COVIELLO T., ALHAIQUE F, VERMONDEN T, HENNINK W E (2010). IPN hydrogels based on Ca(II)-alginate-DexHEMA for biomedical applications. In: -. La Valletta, Malta, 8-11-marzo 2010, vol. 1, p. 100-101

SANDOLO C, BULONE D, MANGIONE M, MARGHERITELLI S, DI MEO C, ALHAIQUE F, MATRICARDI P, COVIELLO T. (2010). Synergistic interaction of Locust Bean Gum and Xanthan investigated by rheology and light scattering. CARBOHYDRATE POLYMERS, vol. 82; p. 733-741, ISSN: 0144-8617, doi: 10.1016/j.carbpol.2010.05.044

COVIELLO T., GRASSI M, MATRICARDI P, ALHAIQUE F, MARGHERITELLI S, BEDIN P, DEREDITA' G (2010). Gel di Guar/borace: caratterizzazione e studi di rilascio. In: XI Convegno Nazionale della Società Italiana di Reologia. Trieste (Italy), May 23-26, vol. XI, p. 189-

D'ARRIGO G, PESCOSOLIDO L, DI MEO C, MATRICARDI P, ALHAIQUE F, COVIELLO T. (2010). Polysaccharidic Hydrogels for Biomedical Applications. In: -. Gargnano Lago di Garda - BS, May 30th - June 4th, 2010, vol. 1, p. 70-70

PESCOSOLIDO L, MATRICARDI P, COVIELLO T., MALDA J, VERMONDEN T, HENNINK W E, ALHAIQUE F (2010). Polysaccharidic IPN Systems Suitable for Biomedical Applications. In: -. Oregon Convention Center Portland, Oregon (U.S.A.), 10-14 luglio 2010, vol. 1, p. 727-

DI MEO C, MANNINA L, LAMANNA R, MATRICARDI P, COVIELLO T., ALHAIQUE F, DENTINI M, CAPITANI D (2010). Tecniche NMR a bassa ed alta risoluzione per lo studio strutturale di polisaccaridi e loro derivati. In: -. Roma, 27-28 maggio 2010, vol. 1, p. 16-16

BOCCHINFUSO G, MAZZUCA C, SANDOLO C, MARGHERITELLI S, ALHAIQUE F, COVIELLO T., PALLESCHI A (2010). Guar Gum and Scleroglucan interactions with borax: experimental and theoretical studies of an unexpected similarity. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 114; p. 13059-13068, ISSN: 1520-6106, doi: 10.1021/jp105838t

ALHAIQUE F, COVIELLO T., MATRICARDI P, DI MEO C, PESCOSOLIDO L, D'ARRIGO G (2010). Polysaccharidic hydrogels for modified drug delivery. In: 2nd Conference, Innovation in Drug Delivery: from preformulation to development through innovative evaluation process. Aix en Provence (France), October 3-6, vol. II, p. 47-47

MATRICARDI P, PONTORIERO M, COVIELLO T., CASADEI MA, ALHAIQUE F (2008). In situ cross-linkable novel alginate-dextran methacrylate IPN hydrogels for biomedical applications. Mechanical characterization and drug delivery properties. BIOMACROMOLECULES, vol. 9; p. 2014-2020, ISSN: 1525-7797, doi: 10.1021/bm800252c

DI MEO C, COVIELLO T., MATRICARDI P, ALHAIQUE F, CAPITANI D, LAMANNA R (2011). Anisotropic enhanced water diffusion in scleroglucan gel tablets. SOFT MATTER, vol. 7; p. 6068-6075, ISSN: 1744-683X, doi: 10.1039/C1SM05190C

PESCOSOLIDO L, SCHUURMAN W, MALDA J, MATRICARDI P, ALHAIQUE F, COVIELLO T., VAN WEEREN P R, DHERT W, HENNINK W E, VERMONDEN T (2011). Hyaluronic acid and Dextran based Semi-IPN Hydrogels as Biomaterials for Bioprinting. BIOMACROMOLECULES, vol. 12; p. 1831-1838, ISSN: 1525-7797, doi: 10.1021/bm200178w

PESCOSOLIDO L, PIRO T, VERMONDEN T, COVIELLO T., ALHAIQUE F, HENNINK W E, MATRICARDI P (2011). Biodegradable IPNs based on oxidized alginate and dextran-HEMA for controlled release of proteins. CARBOHYDRATE POLYMERS, vol. 86; p. 208-213, ISSN: 0144-8617, doi: 10.1016/j.carbpol.2011.04.033

Di Meo C, COVIELLO T., Matricardi P, Alhaique F, Capitani D, Lamanna R (2011). Anisotropic Enhanced Water Diffusion in Scleroglucan/Borax Swelled Tablets Studied by PGSE NMR". In: -. Parma, Italy, 26-28 September, 2011

Matricardi P, Pescosolido L, Di Meo C, COVIELLO T., Alhaique F, Hennink W E (2011). Interpenetrating Polymer Networks Based on Ca(II)-Alginate-DexHEMA Hydrogels Suitable for Biomedical Applications. In: -. Lyon, France, 29-31 May, 2011

PATACHIA S, DOBRITOIU R, COVIELLO T. (2011). Determination of the sorption efficiency of poly(vinyl alcohol)/scleroglucan cryogels, against Cu(2+) ions. ENVIRONMENTAL ENGINEERING AND MANAGEMENT JOURNAL, vol. 10; p. 193-198, ISSN: 1582-9596

Marianecci C, Carafa M, Di Marzio L, Rinaldi F, Di Meo C, Matricardi P, Alhaique F, COVIELLO T. (2011). A New Vesicle-loaded Hydrogel System Suitable for Topical Applications: Preparation and Characterization. JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES, vol. 14; p. 336-346, ISSN: 1482-1826

RUIZ-CARO R, VEIGA M D, DI MEO C, CENCETTI C, COVIELLO T., MATRICARDI P, ALHAIQUE F (2012). Mechanical and drug delivery properties of a chitosan-tartaric acid hydrogel suitable for biomedical applications. JOURNAL OF APPLIED POLYMER SCIENCE, vol. 123; p. 842-849, ISSN: 0021-8995, doi: 10.1002/app.34513

SANDOLO C, PÉCHINÉ S, LE MONNIER A, HOYS S, JANOIR C, COVIELLO T., ALHAIQUE F, COLLIGNON A, FATTAL E, TSAPIS N (2011). Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 79; p. 566-573, ISSN: 0939-6411, doi: 10.1016/j.ejpb.2011.05.011

MATRICARDI P, PITARRESI G, PALUMBO F S, DI MEO C, ALBANESE A, COVIELLO T., CENCETTI C, FIORICA C, GIAMMONA G (2011). Mechanical characterization of polysaccharide/polyaminoacid

hydrogels as potential scaffolds for tissue regeneration. MACROMOLECULAR RESEARCH, vol. 19; p. 1264-1271, ISSN: 1598-5032, doi: 10.1007/s13233-011-1208-y

Carlotta Marianecci, Maria Carafa, Luisa Di Marzio, Federica Rinaldi, Chiara Di Meo, Franco Alhaique, Pietro Matricardi, COVIELLO T. (2011). A New Vesicle-loaded Hydrogel System Suitable for Topical Applications: Preparation and Characterization. In: -. Florence, Italy, November 8-12

Giorgia D’Arrigo, Chiara Di Meo, Silvia Chichiarelli, Elisa Gaucci, COVIELLO T., Franco Alhaique, Pietro Matricardi (2011). Gellan-prednisolone Nanogels. A New Tool for Drug Delivery Applications. In: -. Florence, Italy, November 8-12

Laura Pescosolido, Luigi Feruglio, Rossella Farra, Simona Fiorentino, Italo Colombo, COVIELLO T., Pietro Matricardi, Wim E. Hennink, Tina Vermonden, Mario Grassi (2012). Mesh Size Distribution Determination of Interpenetrating Polymer Networks Hydrogels. SOFT MATTER, vol. 8; p. 7708-7715, ISSN: 1744-683X, doi: 10.1039/c2sm25677k

Giorgia D’Arrigo, Chiara Di Meo, Laura Pescosolido, COVIELLO T., Franco Alhaique, Pietro Matricardi (2012). Calcium Alginate -Dextran Methacrylate IPN Beads as Protecting Carriers for Protein Delivery. JOURNAL OF MATERIALS SCIENCE. MATERIALS IN MEDICINE, vol. 23; p. 1715-1722, ISSN: 0957-4530, doi: 10.1007/s10856-012-4644-0

Chiara Di Meo, Giorgia D’Arrigo, Silvia Chichiarelli, Elisa Gaucci, COVIELLO T., Franco Alhaique, Pietro Matricardi (2011). Gellan-prednisolone nanogels: a new tool for drug delivery applications. In: -. Rome, November 17-19, 2011

Giorgia D’Arrigo, Chiara Di Meo, Silvia Chichiarelli, Elisa Gaucci, COVIELLO T., Franco Alhaique, Pietro Matricardi (2012). Polysaccharide Nanogels as Drug Carriers. In: -. Istanbul, Turkey, 19th-22nd March 2012

Carlotta Marianecci, Maria Carafa, Luisa Di Marzio, Federica Rinaldi, Chiara Di Meo, Franco Alhaique, Pietro Matricardi, COVIELLO T. (2012). Preparation and Characterization of a Combined System Suitable for Topical Applications: Surfactant Vesicles Embedded in a Hydrogel Matrix. In: -. Istanbul, Turkey, 19th-22nd March 2012

Franco Alhaique, Carlotta Marianecci, Maria Carafa, Luisa Di Marzio, Federica Rinaldi, Chiara Di Meo, Pietro Matricardi, COVIELLO T. (2012). Preparazione e caratterizzazione di un nuovo idrogel polisaccaridico contenente strutture vescicolari. In: -. Rimini, Italy, 30 maggio-1 giugno 2012

COVIELLO T., Silvia Margheritelli, Pietro Matricardi, Chiara Di Meo, Franco Alhaique, Mario Grassi (2012). Scleroglucano/borace: studio del comportamento reologico al variare del rapporto reticolante/polimero. In: Atti del XII Convegno della Società Italiana di Reologia. Ustica, Italy, 3-6 luglio 2012

Giorgia D’Arrigo, Chiara Di Meo, Silvia Chichiarelli, Elisa Gaucci, COVIELLO T., Franco Alhaique, Pietro Matricardi (2012). Polysaccharide Nanohydrogels as Drug Carriers. In: -. Quebec City, Canada, July 15-18, 2012

Chiara Di Meo, COVIELLO T., Pietro Matricardi, Franco Alhaique, Donatella Capitani, Raffaele Lamanna (2012). Anomalous enhanced water diffusion in polysaccharide hydrogels studied by PGSE NMR. In: -. Pisa, 17-19 September 2012

Raffaele Lamanna, Chiara Di Meo, COVIELLO T., Pietro Matricardi, Franco Alhaique, Donatella Capitani (2012). Anisotropic enhanced water diffusion in scleroglucan/borax swelled tablets studied by PGSE NMR. In: -. Perugia, Italy, 23-26 September 2012

Giorgia D’Arrigo, Chiara Di Meo, Silvia Chichiarelli, Elisa Gaucci, COVIELLO T., Franco Alhaique, Pietro Matricardi (2012). Polysaccharide nanohydrogels as drug carriers. In: -. Firenze, Italy, 13–16 September 2012

Giorgia D’Arrigo, Chiara Di Meo, Erik Geissler, COVIELLO T., Franco Alhaique, Pietro Matricardi (2012). Hyaluronic acid methacrylate derivatives and calcium alginate interpenetrated hydrogel networks for biomedical applications: physico-chemical characterization and protein release. COLLOID AND POLYMER SCIENCE, vol. 15; p. 1575-1582, ISSN: 0303-402X, doi: 10.1007/s00396-012-2735-6

Montanari E, Capece S, Di Meo C, Meringolo M, Coviello T, Agostinelli E, Matricardi P. Macromol. Biosci. 9/2013. Macromol Biosci. 2013 Sep;13(9):1111. doi: 10.1002/mabi.201370029.

Ansari SA, Matricardi P, Cencetti C, Di Meo C, Carafa M, Mazzuca C, Palleschi A, Capitani D, Alhaique F, Coviello T. Sonication-based improvement of the physicochemical properties of Guar Gum as a potential substrate for modified drug delivery systems. Biomed Res Int. 2013;2013:985259. doi: 10.1155/2013/985259.

Montanari E, Capece S, Di Meo C, Meringolo M, Coviello T, Agostinelli E, Matricardi P. Hyaluronic Acid Nanohydrogels as a Useful Tool for BSAO Immobilization in the Treatment of Melanoma Cancer Cells. Macromol Biosci. 2013 Sep;13(9):1185-94. doi: 10.1002/mabi.201300114.

Matricardi P, Di Meo C, Coviello T, Hennink WE, Alhaique F. Interpenetrating Polymer Networks polysaccharide hydrogels for drug delivery and tissue engineering. Adv Drug Deliv Rev. 2013 Aug;65(9):1172-87. doi: 10.1016/j.addr.2013.04.002.

7. DE PETRIS GIULIA

G. de Petris, A. Troiani. Isotope Effects in Isotope-Exchange Reactions: Evidence for a Large 12C/13C

Kinetic Isotope Effect in the Gas Phase. J. Phys. Chem. A 112, 2507 (2008).

G. de Petris, A, Cartoni, M. Rosi, A. Troiani. The HSSS Radical and the HSSS- Anion. J. Phys. Chem.

A 112, 8471 (2008).

M. Bartolomei, D. Cappelletti, G. de Petris, M. Moix Teixidor, F. Pirani, M. Rosi, F. VecchiocattiviThe .

Intermolecular Potential in NO-N2 and (NO-N2)+ Systems: Implications for the Neutralization of Ionic

Aggregates. Phys. Chem. Chem. Phys. 10, 5993 (2008).

G. de Petris, A. Troiani, M. Rosi, G. Angelini, O. Ursini. Methane Activation by Metal-free

Radical Cations: Experimental Insight into the Reaction Intermediate. Chemistry- Eur. J. 15,

4248 (2009)

G.de Petris, M. R. Festa, L. Galantini, E. Giglio, C. Leggio, N. V. Pavel, A. Troiani. Sodium

Glycodeoxycholate and Glycocholate Mixed Aggregates in Gas and Solution Phases. J. Phys.

Chem. B 113, 7162 (2009)

G. de Petris, A, Cartoni, A. Troiani, G. Angelini, O. Ursini. Water Activation by SO2•+ Ions: An Effective

Source of OH• Radicals. Phys. Chem. Chem. Phys. 11, 9976 (2009)

G. de Petris, A, Cartoni, R. Cipollini, M. Rosi, A. Troiani. Experimental and Theoretical Evidence for

HS4. J. Phys. Chem. A 113, 14420 (2009)

G. de Petris, A. Cartoni, A. Troiani, V. Barone, P. Cimino, G. Angelini, O. Ursini. Double C-H

Activation of Ethane by Metal-Free SO2•+ Radical Cations. Chemistry- Eur. J. 16, 6234 (2010)

G. de Petris. Atmospheric Studies by Laboratory Mass Spectrometers, p. 696 in Beauchemin

D and Matthews DE editors, Elemental and Isotope Ratio Mass Spectrometry. Elsevier; 2010.

(Gross ML and Caprioli RM, editors. The Encyclopedia of Mass Spectrometry; vol. 5)

G. de Petris, A. Cartoni, M. Rosi, V. Barone, C. Puzzarini, A. Troiani. The Proton Affinity and

Gas-Phase Basicity of Sulfur Dioxide. ChemPhysChem 17, 112 (2011)

G. de Petris, G. Angelini, O. Ursini, M. Rosi, A. Troiani. Linking Ion and Neutral Chemistry in C-

H Bond Electrophilic Activation: Generation and Detection of HO2• Reactive Radicals. Angew.

Chem. Int. Ed. Engl. 51, 1455 (2012)

G. de Petris, A. Troiani, M. Rosi, A. Sgamellotti, R. Cipollini. The Azido Oxide N3O. Chem. Phys.

398, 129 (2012)

G. de Petris, M. Rosi, O. Ursini, A. Troiani. The Oxidative Mechanism in Electrophilic C-H

Activation: the Case of CH2F2 and CH2Cl2. Chemistry- As. J. 8, 588 (2013)

N. Dietl, A. Troiani, M. Schlangen, O. Ursini, G. Angelini, Y. Apeloig, G. de Petris, H. Schwarz. Mechanistic Aspects of Gas-Phase Hydrogen-Atom Transfer from Methane to [CO]•+ and [SiO]•+: Why do They Differ? Chemistry- Eur. J. 19, 6662 (2013)

G. de Petris, A. Troiani, M. Rosi, G. Angelini, O. Ursini. Selective Activation of C-Cl and C-F Bonds by SO•+ Radical Cations: an Experimental and Computational Study. ChemPlusChem 78, 1065 (2013)

8.: DI SANTO Roberto

S. B. JENSEN, DI SANTO R., A. K. OLSEN, K. PEDERSEN, R. COSTI, R. CIRILLI, P. CUMMING (2008). Synthesis and cerebral uptake of 1-(1-[11C]methyl-1H-pyrrol-2-yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone a novel tracer for positron emission tomography studies of monoamine oxidase type A. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 1617-1622, ISSN: 0022-2623, doi: 10.1021/jm701378e

DI SANTO R. (2008). Recent patents in antifungal agent discovery. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 18; p. 275-292, ISSN: 1354-3776, doi: 10.1517/13543776.18.3.275

R. CIRILLI, R. COSTI, DI SANTO R., F. GASPARRINI, F. LA TORRE, M. PIERINI, G. SIANI (2009). A rational approach to predict and modulate stereolability of chiral alpha-substituted ketones. CHIRALITY, vol. 21; p. 24-34, ISSN: 0899-0042, doi: 10.1002/chir.20589

DI SANTO R., R. Costi, A. Roux, G. Miele, G. Cucuzzoli Crucitti, A. Iacovo, F. Rosi, A. Lavecchia, L. Marinelli, C. Di Giovanni, E. Novellino, L. Palmisano, M. Andreaotti, R. Amici, CM. Galluzzo, L. Nencioni, AT. Palamara, Y. Pommier, C. Marchand (2008). Novel quinolinonyl diketo acid derivatives as HIV-1

integrase inhibitors: Design, synthesis, and biological activities. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 4744-4750, ISSN: 0022-2623, doi: 10.1021/jm8001422

O. JEGEDE, J. BABU, DI SANTO R., D. J. MCCOLL, J. WEBER, M. E. QUIÑONES-MATEU (2008). HIV Type 1 Integrase Inhibitors: From Basic Research to Clinical Implications. AIDS REVIEWS, vol. 10; p. 172-189, ISSN: 1139-6121

TRAMONTANO E, DI SANTO R. (2010). HIV-1 RT-associated RNase H function inhibitors: recent advances in drug development. CURRENT MEDICINAL CHEMISTRY, vol. 17; p. 2837-2853, ISSN: 0929-8673, doi: 10.2174/092986710792065045

DI SANTO R. (2010). Natural Products as Antifungal Agents Against Clinically Relevant Pathogens. NATURAL PRODUCT REPORTS, vol. 27; p. 1084-1098, ISSN: 0265-0568, doi: 10.1039/b914961a

MAZZARINO M, DE LA TORRE X, DI SANTO R., FIACCO I, ROSI F, BOTRE F (2010). Mass spectrometric characterization of tamoxifene metabolites in human urine utilizing different scan parameters on liquid chromatography/tandem mass Spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 24; p. 749-760, ISSN: 0951-4198, doi: 10.1002/rcm.4432

ALISI, MARIA ALESSANDRA, CAZZOLLA, NICOLA, R. COSTI, ROBERTA, DI SANTO R., ROBERTO, FURLOTTI, GUIDO, GUGLIELMOTTI, ANGELO, POLENZANI, LORENZO (2010). Pyrroloquinolines with serotoninergic activity, process for preparing it and pharmaceutical composition comprising it . WO 2010012611. ACRAF

Cheng D, Valente S, Castellano S, Sbardella G, DI SANTO R., Costi R, Bedford MT, Mai A (2011). Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 4928-4932, ISSN: 0022-2623, doi: 10.1021/jm200453n

DI SANTO R. (2011). Diketo acids derivatives as dual inhibitors of human immunodeficiency virus type 1 integrase and the reverse transcriptase RNase H domain. CURRENT MEDICINAL CHEMISTRY, vol. 18; p. 3335-3342, ISSN: 0929-8673

D. STRANGES, P. O'KEEFFE, G. SCOTTI, DI SANTO R., P.L. HOUSTON. (2008). Competing sigmatropic shift rearrangements in excited allyl radicals. THE JOURNAL OF CHEMICAL PHYSICS, vol. 128; p. 151101-1-151101-4, ISSN: 0021-9606, doi: 10.1063/1.2907714

ZULEIKAMICHELINI, CLEMENTINAMARIAGALLUZZO, DONATELLAR.M. NEGRI, PASQUALINALEONE, ROBERTAAMICI, ROBERTABONA, VINCENZOSUMMA, DI SANTO R., R. COSTI, YVESPOMMIER, CHRISTOPHEMARCHAND, LUCIAPALMISANO, STEFANOVELLA, ANDREACARA (2010). EvaluationofHIV-1integraseinhibitorsonhumanprimarymacrophagesusinga luciferase-basedsingle-cyclephenotypicassay. JOURNAL OF VIROLOGICAL METHODS, vol. 168; p. 272-276, ISSN: 0166-0934

D. De Vita, L. Scipione, S. Tortorella, P. Mellini, B. Di Rienzo, G. Simonetti, FD. D’Auria, S. Panella, R. Cirilli, DI SANTO R., AT. Palamara (2012). Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 49; p. 334-342, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2012.01.034

R Fioravanti, I Celestino, R Costi, G Cuzzucoli Crucitti, L Pescatori, L Mattiello, E Novellino, P Checconi, A T Palamara, L Nencioni, DI SANTO R. (2012). Effects of polyphenol compounds on influenza A virus replication and definition of their mechanism of action. BIOORGANIC & MEDICINAL CHEMISTRY, ISSN: 0968-0896, doi: 10.1016/j.bmc.2012.05.062

Sergio Valente, Ilaria lepore, Carmela Dell'Aversa, Maria Tardugno, Sabrina Castellano, Gianluca Sbardella, Stefano Tomassi, Salvatore Di Maro, Ettore Novellino, DI SANTO R., Roberta Costi, Lucia Altucci, Antonello Mai (2012). Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells. BIOCHIMIE, vol. 94; p. 2308-2313, ISSN: 0300-9084, doi: 10.1016/j.biochi2012.06.003

VALENTI P, NATALIZI T, DI SANTO R., PESCATORI L, CUZZUCOLI CROCITTI G, ILARI A, CHIANCONE E (2012). PIRROLIL-IDROSSAMMATI PER USO NELLA PREVENZIONE E/O NEL TRATTAMENTO DI INFEZIONI BATTERICHE. N. MI2012A0009800980. SAPIENZA UNIVERSITA' DI ROMA E FONDAZIONE ROMA

Giuliana Cuzzucoli Crucitti, Maurizio Botta, DI SANTO R. (2012). Will integrase inhibitors be used as microbicides?. CURRENT HIV RESEARCH, vol. 10; p. 36-41, ISSN: 1570-162X

Costi R, Métifiot M, Esposito F, Cuzzucoli Crucitti G, Pescatori L, Messore A, Scipione L, Tortorella S, Zinzula L, Novellino E, Pommier Y, Tramontano E, Marchand C, Di Santo R. 6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic Acids as Dual Inhibitors of Recombinant HIV-1 Integrase and Ribonuclease H, Synthesized by a Parallel Synthesis Approach. J Med Chem. 2013 Nov 5.

Di Santo R. Inhibiting the HIV Integration Process: Past, Present, and the Future. J Med Chem. 2013 Sep 25.

Taliani S, Pugliesi I, Barresi E, Salerno S, Marchand C, Agama K, Simorini F, La Motta C, Marini AM, Di Leva FS, Marinelli L, Cosconati S, Novellino E, Pommier Y, Di Santo R, Da Settimo F. Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin topoisomerase I (Top1) inhibitors. J Med Chem. 2013 Sep 26;56(18):7458-62. doi: 10.1021/jm400932c.

Costi R, Crucitti GC, Pescatori L, Messore A, Scipione L, Tortorella S, Amoroso A, Crespan E, Campiglia P, Maresca B, Porta A, Granata I, Novellino E, Gouge J, Delarue M, Maga G, Di Santo R. New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J Med Chem. 2013 Sep 26;56(18):7431-41. doi: 10.1021/jm4010187.

Friggeri L, Ballante F, Ragno R, Musmuca I, De Vita D, Manetti F, Biava M, Scipione L, Di Santo R, Costi R, Feroci M, Tortorella S. Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents. J Chem Inf Model. 2013 Jun 24;53(6):1463-74. doi: 10.1021/ci400132q.

9. FABRIZI Giancarlo

BERNINI R, CACCHI S, FABRIZI G., FORTE G, NIEMBRO S, PETRUCCI F, PLEIXATS R, PRASTARO A, SEBASTIAN R M, SOLER R, TRISTANY M, VALLRIBERA A (2008). Phosphine-Free Perfluoro-Tagged Palladium Nanoparticles Supported on Fluorous Silica Gel: Application to the Heck Reaction. ORGANIC LETTERS, vol. 10; p. 561-564, ISSN: 1523-7060, doi: 10.1021/ol7024845

CASADEI M, MATRICARDI P, FABRIZI G., FEENEY M, PAOLICELLI P (2007). Physical gels of a carboxymethyl derivative of scleroglucan: synthesis and characterization. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 67; p. 682-689, ISSN: 0939-6411, doi: 10.1016/j.ejpb.2007.04.010

SGALLA S, FABRIZI G., CIRILLI R, MACONE A, A. BONAMORE, BOFFI A, CACCHI S (2007). Chiral (R)- and (S)-allylic alcohols via a one-pot chemoenzymatic synthesis. TETRAHEDRON-ASYMMETRY, vol. 18; p. 2791-2796, ISSN: 0957-4166, doi: 10.1016/j.tetasy.2007.10.043

R. BERNINI, E. MINCIONE, F. CRISANTE, M. BARONTINI, FABRIZI G., P. GENTILI (2007). Chemoselective and efficient carbomethoxylation of the alcoholic chain of phenols by dimethyl carbonate (DMC). TETRAHEDRON LETTERS, vol. 48; p. 7000-7003, ISSN: 0040-4039, doi: 10.1016/j.tetlet.2007.07.109

SOLER R, CACCHI S, FABRIZI G., FORTE G, MARTIN L, MARTINEZ S, MOLINS E, MORENO-MANAS M, PETRUCCI F, ROIG A, SEBASTIANR.M, VALLRIBERA A (2007). Sonogashira cross-coupling using carbon aerogel doped with palladium nanoparticles; a recoverable and reusable catalyst. SYNTHESIS, vol. 19; p. 3068-3072, ISSN: 0039-7881, doi: 10.1055/s-2007-983888

AMBROGIO I, S. CACCHI, FABRIZI G. (2007). 2-Alkylindoles via palladium-catalyzed reductive cyclization of ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonates. TETRAHEDRON LETTERS, vol. 48; p. 7721-7725, ISSN: 0040-4039, doi: 10.1016/j.tetlet.2007.07.213

AMBROGIO I, ARCADI A, S. CACCHI, FABRIZI G., MARINELLI F (2007). Gold-catalyzed synthesis of 2-substituted, 2,3-disubstituted and 1,2,3-trisubstituted indoles in [bmim]BF4. SYNLETT, vol. --; p. 1775-1779, ISSN: 0936-5214, doi: 10.1055/s-2007-982572

CACCHI S, FABRIZI G., GOGGIAMANI A, PERSIANI D (2008). Palladium-Catalyzed Hydroarylation of Alkynes with Arenediazonium Salts. ORGANIC LETTERS, vol. 10; p. 1597-1600, ISSN: 1523-7060, doi: 10.1021/ol800266e

S. CACCHI, FABRIZI G., E. FILISTI (2008). N-propargylyc-ß-enaminones: common intermediates for the synthesis of polysubstituted pyrroles and pyridines. ORGANIC LETTERS, vol. 10; p. 2629-2632, ISSN: 1523-7060, doi: 10.1021/ol800518j

I. AMBROGIO, FABRIZI G., S. CACCHI, S. T. HENRIKSEN, P. FRISTRUP, D. TANNER, PER-OLA NORRBY (2008). Unusual Selectivity-Determining Factors in the Phosphine-Free Heck Arylation of Allyl Ethers. ORGANOMETALLICS, vol. 27; p. 3187-3195, ISSN: 0276-7333, doi: 10.1021/om800114a

BERNINI R, S. CACCHI, FABRIZI G., SFERRAZZA A (2008). A simple general approach to phenanthridinones via palladium-catalyzed intramolecular direct arene arylation. SYNTHESIS, vol. 67; p. 729-738, ISSN: 0039-7881, doi: 10.1055/s-2008-1032169

R. BERNINI, E. MINCIONE, F. GRISANTE, M. MAURIZIO, FABRIZI G., P. GENTILI (2008). Obtaining new flavanones exhibiting antifungal activities by methyltrioxorhenium-catalyzed epoxidation-methanolysis of flavones. TETRAHEDRON, vol. 64; p. 7561-7566, ISSN: 0040-4020, doi: 10.1016/j.tet.2008.05.101

BARTOLI G, CACCHI S, FABRIZI G., GOGGIAMANI A (2008). Aryl norbornanes and analogues via palladium-catalyzed hydroarylation with arenediazonium tetrafluoroborates. SYNLETT, vol. 16; p. 2508-2512, ISSN: 0936-5214, doi: 10.1055/s-2008-1078051

BERNINI R, S. CACCHI, FABRIZI G., FILISTI E (2008). 2-Arylhydroxytyrosol Derivatives via Suzuki-Miyaura Cross-Coupling. ORGANIC LETTERS, vol. 10; p. 3457-3460, ISSN: 1523-7060, doi: 10.1021/ol8012292

I. AMBROGIO, S. CACCHI, FABRIZI G., A. GOGGIAMANI, S. SGALLA (2009). Regio- and Stereoselective Heck a-Arylation of Cinnamyl Alcohols. SYNLETT, vol. --; p. 620-624, ISSN: 0936-5214, doi: 10.1055/s-0028-1087912

R. BERNINI, S. CACCHI, FABRIZI G., A. SFERRAZZA (2009). 1,2-Disubstituted 4-Quinolones via Copper-Catalyzed Cyclization of 1-(2-Halophenyl)-3-enaminones. SYNTHESIS, vol. --; p. 1209-1219, ISSN: 0039-7881, doi: 10.1055/s-0028-1087990

R. BERNINI, S. CACCHI, FABRIZI G., E. FILISTI, A. SFERRAZZA (2009). Polysubstituted Quinolines from 2-Alkynylanilines and alfa,beta-Ynones through a Sequential Conjugate Addition/Cyclization Process. SYNLETT, vol. --; p. 1245-1250, ISSN: 0936-5214, doi: 10.1055/s-0029-1216734

R. BERNINI, S. CACCHI, FABRIZI G., E. FILISTI, A. SFERRAZZA (2009). 3-Aroylindoles via Copper-Catalyzed Cyclization of N-(2-Iodoaryl)enaminones. SYNLETT, vol. --; p. 1480-1484, ISSN:0936-5214, doi: 10.1055/s-0029-1216742

S. CACCHI, FABRIZI G., A. GOGGIAMANI, A. SFERRAZZA (2009). The Palladium-Catalyzed Reaction of Arenediazonium Tetrafluoroborates with Methyl 4-Hydroxy-2-butenoate. An Approach to 4-Aryl Butenolides and an Expeditious Synthesis of Rubrolide E. SYNLETT, vol. --; p. 1277-1280, ISSN: 0936-5214, doi: 10.1055/s-0028-1088132

R. BERNINI, S. CACCHI, FABRIZI G., G. FORTE, F. PETRUCCI, A. PRASTARO, S. NIEMBRO, A. SHAFIR, A. VALLRIBERA (2009). Alkynylation of Aryl Halides with Perfluoro-Tagged Palladium Nanoparticles Immobilized on Silica Gel under Aerobic, Copper-, and Phosphine-Free Conditions in Water. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 7; p. 2270-2273, ISSN: 1477-0520, doi: 10.1039/b903233a

S. CACCHI, FABRIZI G., A. GOGGIAMANI, A. SFERRAZZA (2009). Palladium-Catalyzed Arylation of the THP Derivative of (Z)-2-Butene-1,4-diol with Arenediazonium Salts and the Synthesis of ß-Aryl-¿-butyrolactones. SYNLETT, vol. --; p. 973-977, ISSN: 0936-5214, doi: 10.1055/s-0028-1087959

S. CACCHI, FABRIZI G., FILISTI E (2009). Palladium-Catalyzed Synthesis of Free-NH Indole 2-Acetamides and Derivatives from Ethyl 3-(o-Trifluoroacetamidoaryl)-1-propargylyc Carbonates. SYNLETT, vol. --; p. 1817-1821, ISSN: 0936-5214, doi: 10.1055/s-0029-1217377

BERNINI R, MINCIONE E, CRISANTE F, BARONTINI M, FABRIZI G. (2009). A new and efficient route for the production of naturally occurring catecholamines. SYNTHESIS, vol. 22; p. 3838-3842, ISSN: 0039-7881, doi: 10.1055/s-0029-1217027

AMBROGIO I, CACCHI S, FABRIZI G., PRASTARO A (2009). 3-(o-Trifluoroacetamidoaryl)-1-propargylic esters: common intermediates for the palladium-catalyzed synthesis of 2-aminomethyl-, 2-vinylic, and 2-alkylindoles. TETRAHEDRON, vol. 65; p. 8916-8929, ISSN: 0040-4020, doi: 10.1016/j.tet.2009.06.113

BERNINI R, FABRIZI G., SFERRAZZA A, S. CACCHI (2009). Copper-Catalyzed C-C Bond Formation via C-H Functionalization: Synthesis of Multisubstituted Indoles from N-(Aryl)enaminones. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 48; p. 8078-8081, ISSN: 1433-7851, doi: 10.1002/anie.200902440

A. PRASTARO, P. CECI, E. CHIANCONE, A. BOFFI, R. CIRILLI, M. COLONE, FABRIZI G., A. STRINGARO, S. CACCHI (2009). Suzuki-Miyaura cross-coupling catalyzed by protein-stabilized palladium nanoparticles under aerobic conditions in water: application to a one-pot chemoenzymatic enantioselective synthesis of chiral biaryl alcohols. GREEN CHEMISTRY, vol. 11; p. 1929-1932, ISSN: 1463-9262, doi: 10.1039/b915184b

S. CACCHI, CIRILLI R, FABRIZI G., SGALLA S, MACONE A, BONAMORE A, BOFFI A (2009). (R)-1-Arylethanols from aryl iodides through a two-step one-pot enantioselective chemoenzymatic process. JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, vol. 61; p. 184-187, ISSN: 1381-1177, doi: 10.1016/j.molcatb.2009.06.009

R. BERNINI, S. CACCHI, FABRIZI G., G. FORTE, F. PETRUCCI, A. PRASTARO, S. NIEMBRO, A. SHAFIR, A. VALLRIBERA (2010). Perfluoro-tagged phosphine-free palladium nanoparticles supported on silica gel: application to alkynylation of aryl halides, Suzuki–Miyaura cross-coupling, and Heck reactions under aerobic conditions. GREEN CHEMISTRY, vol. 12; p. 150-158, ISSN: 1463-9262, doi: 10.1039/b915465e

BERNINI R, MINCIONE E, CRISANTE F, BARONTINI M, FABRIZI G. (2009). A novel use of the recyclable polymer-supported IBX: an efficient chemoselective and regioselective oxidation of phenolic compounds. The case of hydroxytyrosol derivatives. TETRAHEDRON LETTERS, vol. 50; p. 1307-1310, ISSN: 0040-4039, doi: 10.1016/j.tetlet.2009.01.037

PRASTARO A, CECI P, CHIANCONE E, BOFFI A, FABRIZI G., S. CACCHI (2010). Homocoupling of arylboronic acids and potassium aryltrifluoroborates catalyzed by protein-stabilized palladium nanoparticles under air in water. TETRAHEDRON LETTERS, vol. 51; p. 2550-2552, ISSN: 0040-4039, doi: 10.1016/j.tetlet.2010.03.015

BAGNOLI L, S. CACCHI, FABRIZI G., GOGGIAMANI A, SCARPONI C, TIECCO M (2010). Diastereoselective Synthesis of Hexahydro-3H-pyrrolizidin-3-ones through Pd-Catalyzed Carboamination. JOURNAL OF ORGANIC CHEMISTRY, vol. 75; p. 2134-2137, ISSN: 0022-3263, doi: 10.1021/jo1002032

CACCHI S, FABRIZI G., GOGGIAMANI A, SFERRAZZA A (2010). Sonogashira Cross-Coupling of Arenediazonium Salts. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 49; p. 4067-4070, ISSN: 1433-7851, doi: 10.1002/anie.201000472

S. CACCHI, FABRIZI G., GOGGIAMANI A, PERBONI A, SFERRAZZA A, STABILE P (2010). 2,3-Disubstituted Indoles via Palladium-Catalyzed Reaction of 2-Alkynyltrifluoroacetanilides with Arenediazonium Tetrafluoroborates. ORGANIC LETTERS, vol. 12; p. 3279-3281, ISSN: 1523-7060, doi: 10.1021/ol101321g

BARONTINI M, BERNINI R, CRISANTE, FA, FABRIZI G. (2010). Selective and efficient oxidative modifications of flavonoids with 2-iodoxybenzoic acid (IBX). TETRAHEDRON, vol. 66; p. 6047-6053, ISSN: 0040-4020, doi: 10.1016/j.tet.2010.06.014

TORINO D, MOLLICA A, PINNEN F, FELICIANI F, LUCENTE G, FABRIZI G., G. PORTALONE, DAVIS P, LAI J, MA S.-W, PORRECA F, HRUBY V.J (2010). Synthesis and Evaluation of New Endomorphin-2 Analogues Containing (Z)-r,ß-Didehydrophenylalanine (¿ZPhe) Residues. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53; p. 4550-4554, ISSN: 0022-2623, doi: 10.1021/jm1001343

BERRINO R, CACCHI S, FABRIZI G., A. GOGGIAMANI, STABILE P (2010). Arenediazonium tetrafluoroborates in palladium-catalyzed C–P bond-forming reactions. Synthesis of arylphosphonates, -phosphine oxides, and –phosphines. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 8; p. 4518-4520, ISSN: 1477-0520, doi: 10.1039/c0ob00243g

ARCADI A., BLESI F., CACCHI S., FABRIZI G., GOGGIAMANI A. (2011). 2,5,7-Trisubstituted benzo[b]furans through a copper- and/or palladium-catalyzed assembly and functionalization process. TETRAHEDRON LETTERS; p. 5149-5152, ISSN: 0040-4039, doi: 10.1016/j.tetlet.2011.07.122

CACCHI S., FABRIZI G. (2011). Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions. CHEMICAL REVIEWS; p. 215-283, ISSN: 0009-2665, doi: 10.1021/cr100403z

S. Cacchi, E. Caponetti, M. A. Casadei, A. Di Giulio, FABRIZI G., G. Forte, A. Goggiamani, S. Moreno, P. Paolicelli, F. Petrucci, A. Prastaro M. L. Saladino (2012). Suzuki-Miyaura cross-coupling of arenediazonium salts catalyzed by alginate/gellan-stabilized palladium nanoparticles under aerobic conditions in water. GREEN CHEMISTRY, vol. 14; p. 317-320, ISSN: 1463-9262, doi: 10.1039/c2gc15679b

S. Cacchi, FABRIZI G., A. Goggiamani, A. Iazzetti, D. Madec, G. Poli and G. Prestat (2011). Functionalized 2,3-dihydrofurans via palladium-catalyzed oxyarylation of a-allyl-ß-ketoesters . ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9; p. 8233-8236, ISSN: 1477-0520, doi: 10.1039/C1OB06593A

CACCHI S, FABRIZI G., A. GOGGIAMANI (2011). Copper catalysis in the construction of indole and benzo[b]furan rings. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9; p. 641-652, ISSN: 1477-0520, doi: 10.1039/C0OB00501k

CACCHI S, FABRIZI G., A. GOGGIAMANI, SFERRAZZA A (2011). Heck reaction of arenediazonium salts with N,N-diprotected allylamines. Synthesis of cinnamylamines and indoles. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9; p. 1727-1730, ISSN: 1477-0520, doi: 10.1039/C0OB01052A

R. BERNINI, S. CACCHI, FABRIZI G., S. NIEMBRO, A. PRASTARO, A. SHAFIR, A. VALLRIBERA (2009). Perfluoro-Tagged Gold Nanoparticles Immobilized on Fluorous Silica Gel: A Reusable Catalyst for the Benign Oxidation and Oxidative Esterification of Alcohols. CHEMSUSCHEM, vol. 2; p. 1036-1040, ISSN: 1864-5631, doi: 10.1002/cssc.200900211

R. Bernini, F. Crisante, FABRIZI G., P. Gentili (2012). Convenient synthesis of 1-aryl-dihydroxyisochromans exhibiting antioxidant activity. CURRENT ORGANIC CHEMISTRY, vol. 16; p. 1051-1057, ISSN: 1385-2728, doi: 10.2174/138527212800194700

R. Berrino, S. Cacchi, FABRIZI G., A. Goggiamani (2012). 4-Aryl-2-quinolones from 3,3-diarylacrylamides through intramolecular copper-catalyzed C-H functionalization/C-N bond formation. JOURNAL OF ORGANIC CHEMISTRY, vol. 77; p. 2537-2542, ISSN: 0022-3263, doi: 10.1021/jo202427m

S. Cacchi, FABRIZI G., E. Filisti, Eleonora, A.Goggiamani, A. Iazzetti, L. Maurone (2012). Palladium-catalyzed synthesis of 2-amino ketones from propargylic carbonates and secondary amines. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 10; p. 4699-4703, ISSN: 1477-0520, doi: 10.1039/C2OB25670C

G. Cera, S. Piscitelli, M. Chiarucci, FABRIZI G., A. Goggiamani, R. S. Ramón, S.P. Nolan and P M. Bandini (2012). One-pot gold-catalyzed synthesis of azepino[1,2-a]indoles. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 124; p. 10029-10033, ISSN: 1433-7851, doi: 10.1002/anie.201205463

Chiarucci M, Matteucci E, Cera G, Fabrizi G, Bandini M. New entry to polycyclic fused indoles via gold(I)-catalyzed cascade reaction. Chem Asian J. 2013 Aug;8(8):1776-9. doi: 10.1002/asia.201201249.

Sergi M, Montesano C, Odoardi S, Mainero Rocca L, Fabrizi G, Compagnone D, Curini R. Micro extraction by packed sorbent coupled to liquid chromatography tandem mass spectrometry for the rapid and sensitive determination of cannabinoids in oral fluids. J Chromatogr A. 2013 Aug 2;1301:139-46. doi: 10.1016/j.chroma.2013.05.072.

Arcadi A, Blesi F, Cacchi S, Fabrizi G, Goggiamani A, Marinelli F. Palladium-catalyzed cascade reactions of 1-(3-arylprop-2-ynyloxy)-2-bromo benzene derivatives with organoboron compounds. J Org Chem. 2013 May 3;78(9):4490-8. doi: 10.1021/jo400503f.

10. FILIPPI Antonello

C. FRASCHETTI, M. ASCHI, FILIPPI A., A. GIARDINI, M. SPERANZA (2008). Fast stereoselective reactions in electrosprayed Co(II)/neurotransmitter nanodroplets. CHEMICAL COMMUNICATIONS, vol. 22; p. 2544-2546, ISSN: 1359-7345, doi: 10.1039/b801201f

C. FRASCHETTI, NOVARA FR, FILIPPI A., SPERANZA M, TROUT NA, ADCOCK W, MARCANTONI E, RENZI G, ROSELLI G, MARCOLINI M (2009). Gas-phase facial diasteroselectivity of equatorial and axial 4-chloro-adamant-2-yl cations. JOURNAL OF ORGANIC CHEMISTRY, vol. 74; p. 5135-5144, ISSN: 0022-3263, doi: 10.1021/jo9004298

C. FRASCHETTI, SPERANZA M, FILIPPI A. (2010). Does a chiral alcohol really racemize when its OH group is protected with Boyer's reaction?. CHIRALITY, vol. 22; p. 88-91, ISSN: 0899-0042, doi: 10.1002/chir.20710

F. GASPARRINI, PIERINI M, VILLANI C, FILIPPI A., SPERANZA M (2008). Induced-fit in the gas phase: conformational effects on the enantioselectivity of chiral tetra-amido macrocycles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130; p. 522-534, ISSN: 0002-7863, doi: 10.1021/ja073287+

C. FRASCHETTI, M. PIERINI, C. VILLANI, F. GASPARRINI, S. LEVI MORTERA, FILIPPI A., M. SPERANZA (2011). The "Bridge" Game: Role of the Fourth Player in Chiral Recognition. CHEMISTRY-A EUROPEAN JOURNAL, vol. 17; p. 3078-3081, ISSN: 0947-6539, doi: 10.1002/chem.201002828

C. Fraschetti, M. C. Letzel, M. Paletta, J. Mattay, M. Speranza, FILIPPI A., M. Aschi, A.B. Rozhenko (2012). Cyclochiral resorcin[4]arenes as effective enantioselectors in the gas phase. JOURNAL OF MASS SPECTROMETRY, vol. 47; p. 1038-1046, ISSN: 1076-5174, doi: 10.1002/jms.2028

FILIPPI A., C. FRASCHETTI, S. PICCIRILLO, F. RONDINO, B. BOTTA, I. D’ACQUARICA, A. CALCATERRA, M. SPERANZA (2012). Chirality effects on the IRMPD spectra of basket resorcinarene/nucleoside complexed. CHEMISTRY-A EUROPEAN JOURNAL, vol. 18; p. 8320-8328, ISSN: 0947-6539, doi: 10.1002/chem.201200614

Caterina Fraschetti, FILIPPI A., Maria Elisa Crestoni, Claudio Villani, Graziella Roselli, Stefano Levi Mortera, Maurizio Speranza (2012). Enantioselective Supramolecular carriers for Nucleoside Drugs. A Thermodynamic and Kinetic Gas Phase Investigation . JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, ISSN: 1044-0305, doi: 10.1007/s13361-012-0432-9

Fraschetti C, Filippi A, Crestoni ME, Ema T, Speranza M. Unexpected behavior of diastereomeric ions in the GasPhase: a stimulus for pondering on ee measurements by ESI-MS. J Am Soc Mass Spectrom. 2013 Apr;24(4):573-8. doi: 10.1007/s13361-012-0575-8.

11. FORNARINI Simonetta

B.CHIAVARINO, M. E. CRESTONI, FORNARINI S., F. LANUCARA, J. LEMAIRE, P. MAITRE, D. SCUDERI (2008). Infrared Spectroscopy of Isolated Nucleotides. 1. The cyclic 3’,5’-Adenosine Monophosphate Anion. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, vol. 270; p. 111-117, ISSN: 1387-3806, doi: 10.1016/j.ijms.2007.11.011

B. CHIAVARINO, R. CIPOLLINI, M. E. CRESTONI, FORNARINI S., F. LANUCARA, A. LAPI (2008). Probing the Compound I-like Reactivity of a Bare High-Valent Oxo Iron Porphyrin Complex: The Oxidation of Tertiary Amines. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130; p. 3208-3217, ISSN: 0002-7863, doi: 10.1021/ja077286t

CHIAVARINO B, CRESTONI M. E, B. DI RIENZO, FORNARINI S., LANUCARA F (2008). Site-selectivity of protonation in gaseous toluene. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 10(36); p. 5507-5509, ISSN: 1463-9076, doi: 10.1039/b808710e

M. E. CRESTONI, FORNARINI S. (2007). Heme-peptide/protein ions and phosphorous ligands: search for site-specific addition reactions. JBIC, vol. 12; p. 22-35, ISSN: 0949-8257, doi: 10.1007/s00775-006-0159-9

B. CHIAVARINO, M. E. CRESTONI, FORNARINI S., F. LANUCARA, J. LEMAIRE, P. MAITRE, D. SCUDERI (2009). Molecular Complexes of Simple Anions with Electron-Deficient Arenes: Spectroscopic Evidence for Two Types of Structural Motifs for Anion-Arene Interactions. CHEMISTRY-A EUROPEAN JOURNAL, vol. 15; p. 8185-8195, ISSN: 0947-6539, doi: 10.1002/chem.200900822

M. E. CRESTONI, FORNARINI S., F. LANUCARA (2009). Oxygen-Atom Transfer by a Naked Manganese(V)-Oxo-Porphyrin Complex Reveals Axial Ligand Effect. CHEMISTRY-A EUROPEAN JOURNAL, vol. 15; p. 7863-7866, ISSN: 0947-6539, doi: 10.1002/chem.200901361

CRESTONI M. E, FORNARINI S., LANUCARA F, WARREN J, MAYER J. M (2010). Probing Spin-Forbidden Oxygen-Atom Transfer: Gas-Phase Reactions of Chromium-Porphyrin Complexes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132; p. 4336-4343, ISSN: 0002-7863, doi: 10.1021/ja9103638

SINHA R. K, MAÎTRE P, PICCIRILLO S, CHIAVARINO B, CRESTONI M. E, FORNARINI S. (2010). Cysteine radical cation: a distonic structure probed by gas phase IR spectroscopy. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 12; p. 9794-9800, ISSN: 1463-9076, doi: 10.1039/c003576a

R. K. SINHA, B. CHIAVARINO, FORNARINI S., J. LEMAIRE, P. MAITRE, M. E. CRESTONI (2010). Protonated Sulfuric Acid: Vibrational Signatures of the Naked Ion in the Near- and Mid-IR. THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS, vol. 1; p. 1721-1724, ISSN: 1948-7185, doi: 10.1021/jz100458q

C. COLETTI, N. RE, D. SCUDERI, P. MAÎTRE, B. CHIAVARINO, FORNARINI S., F. LANUCARA, R. K. SINHA, M. E. CRESTONI (2010). IRMPD spectroscopy of gaseous protonated S-nitrosocaptopril, a biologically active, synthetic amino acid. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, vol. 12; p. 13455-13467, ISSN: 1463-9076, doi: 10.1039/c0cp00671h

CHIAVARINO B, CRESTONI M. E, FORNARINI S., LANUCARA F, LEMAIRE J, MAÎTRE P, M. CRESTONI (2008). Direct probe of NO vibration in the naked ferric heme nitrosyl complex. CHEMPHYSCHEM, vol. 9; p. 826-828, ISSN: 1439-4235, doi: 10.1002/cphc.200800086

B. CHIAVARINO, M. E. CRESTONI, FORNARINI S., F. LANUCARA, J. LEMAIRE, P. MAITRE (2009). Mid-IR spectroscopy and structural features of protonated carbonic acid in the gas phase. CHEMPHYSCHEM, vol. 10; p. 520-522, ISSN: 1439-4235, doi: 10.1002/cphc.200800795

B. CHIAVARINO, M. E. CRESTONI, FORNARINI S., F. LANUCARA (2010). Probing bare high-valent transition oxo-metal complexes: an electrospray ionization Fourier transfrom ion cyclotron resonance study of reactive intermediates. EUROPEAN JOURNAL OF MASS SPECTROMETRY, vol. 16; p. 407-414, ISSN: 1469-0667, doi: 10.1255/ejms.1042

B. Chiavarino, M. E. Crestoni, FORNARINI S., C. Rovira (2008). Unravelling the Intrinsic Features of NO Binding to Iron(II)- and Iron(III)-Hemes. INORGANIC CHEMISTRY, vol. 47; p. 7792-7801, ISSN: 0020-1669, doi: 10.1021/ic800953w

F. Lanucara, B. Chiavarino, M. E. Crestoni, D. Scuderi, R. K. Sinha, P.Maitre, FORNARINI S. (2011). Naked Five-Coordinate FeIII(NO) Porphyrin Complexes: Vibrational and Reactivity Features. INORGANIC CHEMISTRY, vol. 50; p. 4445-4452, ISSN: 0020-1669, doi: 10.1021/ic200073v

LIN Y, CRESTONI M. E, FORNARINI S., MAYER P. M (2011). A neutralization-reionization and reactivity mass spectrometry study of the generation of neutral hydroxymethylene. JOURNAL OF MASS SPECTROMETRY, vol. 46; p. 546-552, ISSN: 1076-5174, doi: 10.1002/jms.1923

R. K. Sinha, B. Chiavarino, M. E. Crestoni, D. Scuderi, FORNARINI S. (2011). Tyrosine nitration as evidenced by IRMPD spectroscopy. INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, vol. 308; p. 209-216, ISSN: 1387-3806, doi: 10.1016/j.ijms.2011.07.012

Barbara Chiavarino, Maria Elisa Crestoni, Otto Dopfer, Philippe Maitre, FORNARINI S. (2012). Benzylium versus Tropylium Ion Dichotomy: Vibrational Spectroscopy of Gaseous C8H9+ Ions. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 51; p. 4947-4949, ISSN: 1433-7851, doi: 10.1002/anie.201200558

Maria Elisa Crestoni, Barbara Chiavarino, Joel Lemaire, Philippe Maitre, FORNARINI S. (2012). IR spectroscopy of gaseous fluorocarbon ions: the perfluoroethyl anion. CHEMICAL PHYSICS, vol. 398; p. 118-123, ISSN: 0301-0104, doi: 10.1016/j.chemphys.2011.03.005

Maria Elisa Crestoni, FORNARINI S. (2012). Jahn-Teller Distortion of Hydrocarbon Cations Probed by Infrared Photodissociation Spectroscopy. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, vol. 51; p. 7373-7375, ISSN: 1433-7851, doi: 10.1002/anie.201201650

Barbara Chiavarino, Maria Elisa Crestoni, FORNARINI S., Simone Taioli, Ines Mancini, Paolo Tosi (2012). Infrared spectroscopy of copper-resveratrol complexes: A joint experimental and theoretical study. THE JOURNAL OF CHEMICAL PHYSICS, vol. 137; p. 024307-1-024307-9, ISSN: 0021-9606, doi: 10.1063/1.4732583

Ciavardini A, Rondino F, Paladini A, Speranza M, Fornarini S, Satta M, Piccirillo S. The effect of fluorine substitution on chiral recognition: interplay of CHπ, OHπ and CHF interactions in gas-phase complexes of 1-aryl-1-ethanol with butan-2-ol. Phys Chem Chem Phys. 2013 Oct 23;15(44):19360-70. doi: 10.1039/c3cp53215a.

Chiavarino B, Crestoni ME, Lemaire J, Maitre P, Fornarini S. Communication: Infrared spectroscopy of protonated allyl-trimethylsilane: Evidence for the β-silyl effect. J Chem Phys. 2013 Aug 21;139(7):071102. doi: 10.1063/1.4818729.

Chiavarino B, Maitre P, Fornarini S, Crestoni ME. Cyanide-arene Meisenheimer complex generated in electrospray ionization mass spectrometry using acetonitrile as a solvent. J Am Soc Mass Spectrom. 2013 Oct;24(10):1603-7. doi: 10.1007/s13361-013-0703-0.

Chiavarino B, Crestoni ME, Fornarini S, Scuderi D, Salpin JY. Interaction of cisplatin with adenine and guanine: a combined IRMPD, MS/MS, and theoretical study. J Am Chem Soc. 2013 Jan 30;135(4):1445-55. doi: 10.1021/ja309857d.

12. MAI Antonello

RAGNO R, SIMEONI S, D. ROTILI, CAROLI A, BOTTA G, BROSCH G, MASSA S, MAI A. (2008). Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 43; p. 621-632, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2007.05.004

ILLI B, DELLO RUSSO C, COLUSSI C, ROSATI J, PALLAORO M, SPALLOTTA F, ROTILI D, VALENTE S, RAGONE G, MARTELLI F, BIGLIOLI P, STEINKUHLER C, GALLINARI P, MAI A., CAPOGROSSI M. C, GAETANO C (2008). Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling. CIRCULATION RESEARCH, vol. 102; p. 51-58, ISSN: 0009-7330, doi: 10.1161/CIRCRESAHA.107.157305

G. Simonetti, C. Passariello, D. Rotili, MAI A., E. Garaci, AT. Palamara (2007). Histone deacetylase inhibitors may reduce pathogenicity and virulence in Candida albicans. FEMS YEAST RESEARCH, vol. 7; p. 1371-1380, ISSN: 1567-1356, doi: 10.1111/j.1567-1364.2007.00276.x

MAI A., JELICIC K, D. ROTILI, DI NOIA A, ALFANI E, VALENTE S, ALTUCCI L, NEBBIOSO A, MASSA S, GALANELLO R, BROSCH G, MIGLIACCIO AR, MIGLIACCIO G (2007). Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia. MOLECULAR PHARMACOLOGY, vol. 72; p. 1111-1123, ISSN: 0026-895X, doi: 10.1124/mol.107.036772

CANCIO R, MAI A., D. ROTILI, ARTICO M, SBARDELLA G, CLOTET-CODINA I, ESTÉ JA, CRESPAN E, ZANOLI S, HUBSCHER U, SPADARI S, MAGA G (2007). Slow-, Tight-Binding HIV-1 Reverse Transcriptase Non-Nucleoside Inhibitors Highly Active against Drug-Resistant Mutants. CHEMMEDCHEM, vol. 2; p. 445-448, ISSN: 1860-7179, doi: 10.1002/cmdc.200600310

MAI A., ARTICO M, ROTILI D, TARANTINO D, CLOTET-CODINA I, ARMAND-UGÓN M, RAGNO R, SIMEONI S, SBARDELLA G, NAWROZKIJ M. B, SAMUELE A, MAGA G, ESTÉ J. A (2007). Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains. JOURNAL OF MEDICINAL CHEMISTRY, vol. 50; p. 5412-5424, ISSN: 0022-2623, doi: 10.1021/jm070811e

MAI A., VALENTE S, D. ROTILI, MASSA S, BOTTA G, BROSCH G, MICELI M, NEBBIOSO A, ALTUCCI L (2007). Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity. THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 39; p. 1510-1522, ISSN: 1357-2725, doi: 10.1016/j.biocel.2007.03.020

MAI A. (2007). The therapeutic uses of chromatin-modifying agents. EXPERT OPINION ON THERAPEUTIC TARGETS, vol. 11; p. 835-851, ISSN: 1472-8222, doi: 10.1517/14728222.11.6.835

MAI A., S. VALENTE, D. CHENG, A. PERRONE, R. RAGNO, S. SIMEONI, G. SBARDELLA, G. BROSCH, M.T. BEDFORD (2007). Synthesis and Biological Validation of Novel Synthetic Histone/Protein Methyltransferase Inhibitors. CHEMMEDCHEM, vol. 2; p. 987-991, ISSN: 1860-7179, doi: 10.1002/cmdc.200700023

R. RAGNO, SILVIA SIMEONI, SABRINA CASTELLANO, CATERINA VICIDOMINI, MAI A., ANNA TRAMONTANO, CLAUDIA BONACCINI, PATRICK TROJER, D INGO BAUER, GERALD BROSCH, GIANLUCA SBARDELLA (2007). Small Molecole Inhibitors of Histone Arginine Methyltransferases:

Homology Modeling, Molecular Docking, Binding Mode Analysis, and Biological Evaluation. JOURNAL OF MEDICINAL CHEMISTRY, vol. 50; p. 1241-1253, ISSN: 0022-2623, doi: 10.1021/jm061213n

BOTTA M, CORELLI F, PETRICCI E, RADI M, MAGA G, ESTÉ J. A, MAI A. (2007). Preparation of pyrimidine and pyrimidinone derivatives and their use for the treatment of HIV infections. WO 2007043094. Università di Siena

SINCLAIR D. A, MAI A. (2007). Sirtuin-inhibiting sirtinol analogs for cancer treatment. WO 2007084162. Harvard University

MAI A., MINUCCI S, THALER F, PAIN G, COLOMBO A, GAGLIARDI S (2007). Preparation of N-hydroxycinnamoylamides and related compounds as inhibitors of histone deacetylase. WO 2007113249. DAC SRL

SBARDELLA G, CASTELLANO S, VICIDOMINI C, ROTILI D, NEBBIOSO A, MICELI M, ALTUCCI L, MAI A. (2008). Identification of long chain alkylidenemalonates as novel small molecule modulators of histone acetyltransferases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18; p. 2788-2792, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2008.04.017

MAI A., PERRONE A, NEBBIOSO A, D. ROTILI, VALENTE S, TARDUGNO M, MASSA S, DE BELLIS F, ALTUCCI L (2008). Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18; p. 2530-2535, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2008.03.055

SAMUELE A, FACCHINI M, ROTILI D, MAI A., ARTICO M, ARMAND-UGÓN M, ESTÉ JA, MAGA G (2008). Substrate-induced stable enzyme-inhibitor complex formation allows tight binding of novel 2-aminopyrimidin-4(3H)-ones to drug-resistant HIV-1 reverse transcriptase mutants. CHEMMEDCHEM, vol. 3,9; p. 1412-1418, ISSN: 1860-7179, doi: 10.1002/cmdc.200800051

MIGLIACCIO AR, D. ROTILI, NEBBIOSO A, ATWEH G, MAI A. (2008). Histone deacetylase inhibitors and hemoglobin F induction in beta-thalassemia. THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 40; p. 2341-2347, ISSN: 1357-2725, doi: 10.1016/j.biocel.2008.04.024

NAWROZKIJ MB, D. ROTILI, TARANTINO D, BOTTA G, EREMIYCHUK AS, MUSMUCA I, RAGNO R, SAMUELE A, ZANOLI S, ARMAND-UGÓN M, CLOTET-CODINA I, NOVAKOV IA, ORLINSON BS, MAGA G, ESTÉ JA, ARTICO M, MAI A. (2008). 5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 4641-4652, ISSN: 0022-2623, doi: 10.1021/jm800340w

SCOGNAMIGLIO A, NEBBIOSO A, MANZO F, VALENTE S, MAI A., ALTUCCI L (2008). HDAC-class II specific inhibition involves HDAC proteasome-dependent degradation mediated by RANBP2. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, vol. 1783; p. 2030-2038, ISSN: 0304-4165, doi: 10.1016/j.bbamcr.2008.07.007

CIRILLI R, FERRETTI R, LA TORRE F, BORIONI A, FARES V, CAMALLI M, FAGGI C, ROTILI D, MAI A. (2009). Chiral HPLC separation and absolute configuration of novel S-DABO derivatives. CHIRALITY, vol. 21; p. 604-612, ISSN: 0899-0042, doi: 10.1002/chir.20654

MAI A., ALTUCCI L (2009). Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead. THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 41; p. 199-213, ISSN: 1357-2725, doi: 10.1016/j.biocel.2008.08.020

MAI A., VALENTE S, NEBBIOSO A, SIMEONI S, RAGNO R, MASSA S, BROSCH G, DE BELLIS F, MANZO F, ALTUCCI L (2009). New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations. THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 41; p. 235-247, ISSN: 1357-2725, doi: 10.1016/j.biocel.2008.09.002

COLUSSI C, MOZZETTA C, GURTNER A, ILLI B, ROSATI J, STRAINO S, RAGONE G, PESCATORI M, ZACCAGNINI G, ANTONINI A, MINETTI G, MARTELLI F, PIAGGIO G, GALLINARI P, STEINKULHER C, CLEMENTI E, DELL'AVERSANA C, ALTUCCI L, MAI A., CAPOGROSSI MC, PURI PL, GAETANO C (2008). HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 105; p. 19183-19187, ISSN: 0027-8424, doi: 10.1073/pnas.0805514105

LARA E, MAI A., CALVANESE V, ALTUCCI L, LOPEZ-NIEVA P, MARTINEZ-CHANTAR ML, VARELA-REY M, ROTILI D, NEBBIOSO A, ROPERO S, MONTOYA G, OYARZABAL J, VELASCO S, SERRANO M, WITT M, VILLAR-GAREA A, INHOF A, MATO JM, ESTELLER M, FRAGA MF (2009). Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. ONCOGENE, vol. 28; p. 781-791, ISSN: 0950-9232, doi: 10.1038/onc.2008.436

DUONG V, BRET C, ALTUCCI L, MAI A., DURAFFOURD C, LOUBERSAC J, HARMAND PO, BONNET S, VALENTE S, MAUDELONDE T, CAVAILLES V, BOULLE N (2008). Specific activity of class II histone

deacetylases in human breast cancer cells. MOLECULAR CANCER RESEARCH, vol. 6; p. 1908-1919, ISSN: 1541-7786, doi: 10.1158/1541-7786.MCR-08-0299

MAI A., D. ROTILI, TARANTINO D, NEBBIOSO A, CASTELLANO S, SBARDELLA G, TINI M, ALTUCCI L (2009). Identification of 4-hydroxyquinolines inhibitors of p300/CBP histone acetyltransferases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19; p. 1132-1135, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2008.12.097

MAI A., CHENG D, BEDFORD M. T, VALENTE S, NEBBIOSO A, PERRONE A, BROSCH G, SBARDELLA G, DE BELLIS F, MICELI M, ALTUCCI L (2008). Epigenetric Multiple Ligands: Mixed Histone/Protein Methyltransferase, Acetyltransferase, and Class III Deacetylase (Sirtuin) Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 2279-2290, ISSN: 0022-2623, doi: 10.1021/jm701595q

D. Rotili, G. Simonetti, A. Savarino, A. Palamara, AR. Migliaccio, MAI A. (2009). Non-cancer uses of histone deacetylase inhibitors: effects on infectious diseases and ß-hemoglobinopathies. CURRENT TOPICS IN MEDICINAL CHEMISTRY, vol. 9; p. 272-291, ISSN: 1568-0266, doi: 10.2174/156802609788085296

A. Savarino, MAI A., S. Norelli, S. El Daker, S. Valente, D. Rotili, L. Altucci, A. Palamara, E. Garaci (2009). "Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence. RETROVIROLOGY, vol. 6; p. 52-52, ISSN: 1742-4690, doi: 10.1186/1742-4690-6-52

MARINA NALDI, NATALIA CALONGHI, LANFRANCO MASOTTI, CAROLA PAROLIN, SERGIO VALENTE, MAI A., VINCENZA ANDRISANO (2009). Histone post-translational modifications by HPLC-ESI-MS after HT29 cell treatment with HDAC inhibitors. PROTEOMICS, vol. 9; p. 5437-5445, ISSN: 1615-9853, doi: 10.1002/pmic.200800866

SERGIO VALENTE, MARIAROSARIA CONTE, MARIA TARDUGNO, SILVIO MASSA, ANGELA NEBBIOSO, LUCIA ALTUCCI, MAI A. (2009). Novel pyrrole-based hydroxamates and 2-aminoanilides: Histone deacetylase inhibition and in-cell activities. CHEMMEDCHEM, vol. 4; p. 1411-1415, ISSN: 1860-7179, doi: 10.1002/cmdc.200900082

MANZO, F, TAMBARO, F.P, MAI A., A, ALTUCCI, L (2009). Histone acetyltransferase inhibitors and preclinical studies. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 19; p. 761-774, ISSN: 1354-3776, doi: 10.1517/13543770902895727

MAI A., SERGIO VALENTE, SARAH MEADE, VINCENZO CARAFA, MARIA TARDUGNO, ANGELA NEBBIOSO, ANDREA GALMOZZI, NICO MITRO, EMMA DE FABIANI, LUCIA ALTUCCI AND ALEKSEY KAZANTSEV (2009). Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 52; p. 5496-5504, ISSN: 0022-2623, doi: 10.1021/jm9008289

E BORBONE, MT BERLINGIERI, F DE BELLIS, A NEBBIOSO, G CHIAPPETTA, MAI A., L ALTUCCI, AND A FUSCO (2010). Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation. ONCOGENE, vol. 29; p. 105-116, ISSN: 0950-9232, doi: 10.1038/onc.2009.306

LIU Z, MAI A., SUN J (2010). Lysine Acetylation Regulates Bruton’s Tyrosine Kinase in B Cell Activation. JOURNAL OF IMMUNOLOGY, vol. 184; p. 244-254, ISSN: 0022-1767, doi: 10.4049/jimmunol.0902324

FLORIAN THALER, ANDREA COLOMBO, MAI A., RAFFAELLA AMICI, CHIARA BIGOGNO, ROBERTO BOGGIO, ANNA CAPPA, SIMONE CARRARA, TIZIANA CATAUDELLA, FULVIA FUSAR, ELEONORA GIANTI, SAMUELE JOPPOLO DI VENTIMIGLIA, MAURIZIO MORONI, DAVIDE MUNARI, GILLES PAIN, NICKOLAS REGALIA, LUCA SARTORI, STEFANIA VULTAGGIO, GIULIO DONDIO, STEFANIA GAGLIARDI, SAVERIO MINUCCI, CIRO MERCURIO, MARIO VARASI (2010). Synthesis and Biological Evaluation of N-Hydroxyphenylacrylamides and N-Hydroxypyridin-2-ylacrylamides as Novel Histone Deacetylase Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53; p. 822-839, ISSN: 0022-2623, doi: 10.1021/jm901502p

FRANCESCO SPALLOTTA, JESSICA ROSATI, STEFANIA STRAINO, SIMONA NANNI, ANNALISA GRASSELLI, VALERIA AMBROSINO, DANTE ROTILI, SERGIO VALENTE, ANTONELLA FARSETTI, MAI A., MAURIZIO C. CAPOGROSSI, CARLO GAETANO, BARBARA ILLI (2010). Nitric Oxide Determines Mesodermic Differentiation of Mouse Embryonic Stem Cells by Activating Class IIa Histone Deacetylases: Potential Therapeutic Implications in a Mouse Model of Hindlimb Ischemia. STEM CELLS, vol. 28; p. 431-442, ISSN: 1066-5099

SABRINA CASTELLANO, CIRO MILITE, RINO RAGNO, SILVIA SIMEONI, MAI A., VITTORIO LIMONGELLI, ETTORE NOVELLINO, INGO BAUER, GERALD BROSCH, ASTRID SPANNHOFF, DONGHANG CHENG, MARK T. BEDFORD, GIANLUCA SBARDELLA (2010). Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1). CHEMMEDCHEM, vol. 5; p. 398-414, ISSN: 1860-7179, doi: 10.1002/cmdc.200900459

HUAQING ZHU, LIMEI SHAN, PETER W. SCHILLER, MAI A., TIANQING PENG (2010). Histone deacetylase-3 Activation Promotes TNF-a Expression in Cardiomyocytes During Lipopolysaccharide Stimulation. THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 285; p. 9429-9436, ISSN: 0021-9258, doi: 10.1074/jbc.M109.071274

BINDA C, S. VALENTE, ROMANENGHI M, PILOTTO S, CIRILLI R, KARYTINOS A, CIOSSANI G, BOTRUGNO OA, FORNERIS F, TARDUGNO M, EDMONDSON DE, MINUCCI S, MATTEVI A, MAI A. (2010). Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 132; p. 6827-6833, ISSN: 0002-7863, doi: 10.1021/ja101557k

COLUSSI C, ILLI B, ROSATI J, SPALLOTTA F, FARSETTI A, GRASSELLI A, MAI A., CAPOGROSSI MC, GAETANO C (2010). Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment. PHARMACOLOGICAL RESEARCH, vol. 62; p. 3-10, ISSN: 1043-6618, doi: 10.1016/j.phrs.2010.02.014

COLUSSI C, BERNI R, ROSATI J, STRAINO S, VITALE S, SPALLOTTA F, BARUFFI S, BOCCHI L, DELUCCHI F, ROSSI S, SAVI M, ROTILI D, QUAINI F, MACCHI E, STILLI D, MUSSO E, MAI A., GAETANO C, CAPOGROSSI MC (2010). The histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces cardiac arrhythmias in dystrophic mice. CARDIOVASCULAR RESEARCH, vol. 87; p. 73-82, ISSN: 0008-6363, doi: 10.1093/cvr/cvq035

SPALLOTTA F, ROSATI J, STRAINO S, NANNI S, GRASSELLI A, AMBROSINO V, ROTILI D, VALENTE S, FARSETTI A, MAI A., CAPOGROSSI MC, GAETANO C, ILLI B (2010). Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia. STEM CELLS, vol. 28; p. 431-442, ISSN: 1066-5099, doi: 10.1002/stem.300

THALER F, VARASI M, COLOMBO A, BOGGIO R, MUNARI D, REGALIA N, ROZIO MG, REALI V, RESCONI AE, MAI A., GAGLIARDI S, DONDIO G, MINUCCI S, MERCURIO C (2010). Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors. CHEMMEDCHEM, vol. 5; p. 1359-1372, ISSN: 1860-7179, doi: 10.1002/cmdc.201000166

RUOTOLO R, TOSI F, VERNARECCI S, P. BALLARIO, MAI A., FILETICI P, OTTONELLO S (2010). Chemogenomic profiling of the cellular effects associated with histone H3 acetylation impairment by a quinoline-derived compound. GENOMICS, vol. 96; p. 272-280, ISSN: 0888-7543, doi: 10.1016/j.ygeno.2010.08.005

COLUSSI C, BANFI C, BRIOSCHI M, TREMOLI E, STRAINO S, SPALLOTTA F, MAI A., ROTILI D, CAPOGROSSI MC, GAETANO C (2010). Proteomic profile of differentially expressed plasma proteins from dystrophic mice and following suberoylanilide hydroxamic acid treatment. PROTEOMICS. CLINICAL APPLICATIONS, vol. 4; p. 71-83, ISSN: 1862-8346, doi: 10.1002/prca.200900116

COLUSSI C, ROSATI J, STRAINO S, SPALLOTTA F, BERNI R, STILLI D, ROSSI S, MUSSO E, MACCHI E, MAI A., SBARDELLA G, CASTELLANO S, CHIMENTI C, FRUSTACI A, NEBBIOSO A, ALTUCCI L, CAPOGROSSI MC, GAETANO C (2011). N-epsilon-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 108; p. 2795-2800, ISSN: 0027-8424

MILITE C, CASTELLANO S, BENEDETTI R, TOSCO A, CILIBERTI C, VICIDOMINI C, BOULLY L, FRANCI G, ALTUCCI L, MAI A., SBARDELLA G (2011). Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs). BIOORGANIC & MEDICINAL CHEMISTRY, vol. 19; p. 3690-3701, ISSN: 0968-0896

VARASI M, THALER F, ABATE A, BIGOGNO C, BOGGIO R, CARENZI G, CATAUDELLA T, DAL ZUFFO R, FULCO MC, ROZIO MG, MAI A., DONDIO G, MINUCCI S, MERCURIO C (2011). Discovery, Synthesis, and Pharmacological Evaluation of Spiropiperidine Hydroxamic Acid Based Derivatives as Structurally Novel Histone Deacetylase (HDAC) Inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 3051-3064, ISSN: 0022-2623

ROTILI D, TARANTINO D, ARTICO M, NAWROZKIJ MB, GONZALEZ-ORTEGA E, CLOTET B, SAMUELE A, ESTE, JA, MAGA G, MAI A. (2011). Diarylpyrimidine-Dihydrobenzyloxopyrimidine Hybrids: New, Wide-Spectrum Anti-HIV-1 Agents Active at (Sub)-Nanomolar Level. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 3091-3096, ISSN: 0022-2623, doi: 10.1021/jm101626c

SAITO S, LASKY JA, GUO W, NGUYEN H, MAI A., DANCHUK S, SULLIVAN DE, SHAN B (2011). PHARMACOLOGICAL INHIBITION OF HDAC6 ATTENUATES ENDOTHELIAL BARRIER DYSFUNCTION INDUCED BY THROMBIN. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 408; p. 630-634, ISSN: 0006-291X

MG Lewis, S. Dafonseca, N. Chamont, A. Palamara, M. Tardugno, MAI A., M. Collins, WL. Wagner, J. Yalley-Ogunro, J. Greenhouse, B. Chirullo, S. Norelli, E. Garaci, A. Savarino (2011). Gold drug

auranofin restricts the viral reservoir in the monkey AIDS model and induces containment of viral load following ART suspension. AIDS, vol. 25(11); p. 1347-1356, ISSN: 0269-9370, doi: 10.1097/QAD.0b013e328347bd77

Angela Orecchia, Claudia Scarponi, Francesca Di Felice, Elisa Cesarini, Simona Avitabile, MAI A., Maria Luisa Mauro, Valentina Sirri, Giovanna Zambruno, Cristina Albanesi, Giorgio Camilloni, Cristina M. Failla (2011). Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells. PLOS ONE, vol. 6; p. e24307-, ISSN: 1932-6203, doi: 10.1371/journal.pone.0024307

L. MOSCA, ROTILI D, TEMPERA I, MASCI A, FONTANA M, CHIARALUCE R, MASTROMARINO P, D'ERME M, MAI A. (2011). Biological effects of MC2050, a quinazoline-based PARP-1 inhibitor, in human neuroblastoma and EBV-positive Burkitt's lymphoma cells. CHEMMEDCHEM, vol. 6; p. 606-611, ISSN: 1860-7179, doi: 10.1002/cmdc.201000536

VALENTE S, TARDUGNO M, CONTE M, CIRILLI R, PERRONE A, RAGNO R, SIMEONI S, A. TRAMONTANO, MASSA S, NEBBIOSO A, MICELI M, FRANCI G, BROSCH G, ALTUCCI L, MAI A. (2011). Novel Cinnamyl Hydroxyamides and 2-Aminoanilides as Histone Deacetylase Inhibitors: Apoptotic Induction and Cytodifferentiation Activity. CHEMMEDCHEM, vol. 6; p. 698-712, ISSN: 1860-7179, doi: 10.1002/cmdc.201000535

Cheng D, Valente S, Castellano S, Sbardella G, Di Santo R, Costi R, Bedford MT, MAI A. (2011). Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 4928-4932, ISSN: 0022-2623, doi: 10.1021/jm200453n

Ragno R, Gioia U, Laneve P, Bozzoni I, MAI A., Caffarelli E. (2011). Identification of Small-Molecule Inhibitors of the XendoU Endoribonucleases Family. CHEMMEDCHEM, vol. 6; p. 1797-1805, ISSN: 1860-7179, doi: 10.1002/cmdc.201100281

I. MUSMUCA, A. CAROLI, MAI A., N. KAUSHIK-BASU, P. ARORA, R. RAGNO (2010). Combining 3-D QSAR with Ligand Based and Structure Based Alignment Procedures for in Silico Screening of New Hepatitis C Virus NS5B Polymerase Inhibitors. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 50; p. 662-676, ISSN: 1549-9596, doi: 10.1021/ci9004749

Nebbioso A, Manzo F, Miceli M, Conte M, Manente L, Baldi A, De Luca A, Rotili D, Valente S, MAI A., Usiello A, Gronemeyer H, Altucci L (2009). Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC-MEF2 complexes. EMBO REPORTS, vol. 10; p. 776-782, ISSN: 1469-221X, doi: 10.1038/embor.2009.88

Valente S, Conte M, Tardugno M, Massa S, Nebbioso A, Altucci L, MAI A. (2009). Pyrrole-based hydroxamates and 2-aminoanilides: histone deacetylase inhibition and cellular activities. CHEMMEDCHEM, vol. 4, ISSN: 1860-7179, doi: 10.1002/cmdc.200900082

Palacios D, Mozzetta C, Consalvi S, Caretti G, Saccone V, Proserpio V, Marquez VE, Valente S, MAI A., Forcales SV, Sartorelli V, Puri PL (2010). TNF/p38a/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. CELL STEM CELL, vol. 7, ISSN: 1934-5909, doi: 10.1016/j.stem.2010.08.013

Nebbioso A, Dell'Aversana C, Bugge A, Sarno R, Valente S, Rotili D, Manzo F, Teti D, Mandrup S, Ciana P, Maggi A, MAI A., Gronemeyer H, Altucci L (2010). HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation. JOURNAL OF MOLECULAR ENDOCRINOLOGY, vol. 45, ISSN: 0952-5041, doi: 10.1677/JME-10-0043

Valente S, Tomassi S, Tempera G, Saccoccio S, Agostinelli E, MAI A. (2011). Novel reversible monoamine oxidase A inhibitors: highly potent and selective 3-(1H-pyrrol-3-yl)-2-oxazolidinones. . JOURNAL OF MEDICINAL CHEMISTRY, vol. 54; p. 8228-8232, ISSN: 0022-2623, doi: 10.1021/jm201011x

ROTILI D, ALTUN M, HAMED RB, LOENARZ C, THALHAMMER A, HOPKINSON RJ, TIAN YM, RATCLIFFE PJ, MAI A., KESSLER BM, SCHOFIELD CJ. (2011). Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions. CHEMICAL COMMUNICATIONS; p. 1488-1490, ISSN: 1359-7345, doi: 10.1039/c0cc04457a

PASCO MY, ROTILI D, ALTUCCI L, FARINA F, ROULEAU GA, MAI A., NÉRI C (2010). Characterization of sirtuin inhibitors in nematodes expressing a muscular dystrophy protein reveals muscle cell and behavioral protection by specific sirtinol analogues. JOURNAL OF MEDICINAL CHEMISTRY, vol. 53; p. 1407-1411, ISSN: 0022-2623, doi: 10.1021/jm9013345

MAI A., ROTILI D, VALENTE S, KAZANTSEV AG (2009). Histone deacetylase inhibitors and neurodegenerative disorders: holding the promise. . CURRENT PHARMACEUTICAL DESIGN, vol. 15; p. 3940-3957, ISSN: 1381-6128, doi: 10.2174/138161209789649349

Upadhyay AK, Rotili D, Han JW, Hu R, Chang Y, Labella D, Zhang X, Yoon YS, MAI A., Cheng X. (2012). An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji

demethylases. JOURNAL OF MOLECULAR BIOLOGY, vol. 416; p. 319-327, ISSN: 1089-8638, doi: 10.1016/j.jmb.2011.12.036

Sbardella G, MAI A., Bartolini S, Castellano S, Cirilli R, Rotili D, Milite C, Santoriello M, Orlando S, Sciamanna I, Serafino A, Lavia P, Spadafora C. (2011). Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. JOURNAL OF MEDICINAL CHEMISTRY, ISSN: 0022-2623, doi: 10.1021/jm200734j

ROTILI D., ALTUN M, KAWAMURA A, WOLF A, FISCHER R, LEUNG IK, MACKEEN MM, TIAN YM, RATCLIFFE PJ, MAI A., KESSLER BM, SCHOFIELD CJ (2011). A photoreactive small-molecule probe for 2-oxoglutarate oxygenases. CHEMISTRY & BIOLOGY; p. 642-654, ISSN: 1074-5521, doi: 10.1016/j.chembiol.2011.03.007

ROTILI D., CARAFA V, TARANTINO D, BOTTA G, NEBBIOSO A, ALTUCCI L, MAI A. (2011). Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile. BIOORGANIC & MEDICINAL CHEMISTRY; p. 3659-3668, ISSN: 0968-0896, doi: 10.1016/j.bmc.2011.01.025

MELI M, TOLOMEO M, GRIFANTINI M, MAI A., CAPPELLACCI L, PETRELLI R, ROTILI D, FERRO A, SAIKO P, SZEKERES T, DUSONCHET L (2011). Histone deacetylase inhibition modulates deoxyribonucleotide pools and enhances the antitumor effects of the ribonucleotide reductase inhibitor 3'-C-methyladenosine in leukaemia cells. INTERNATIONAL JOURNAL OF ONCOLOGY, ISSN: 1019-6439, doi: 10.3892/ijo.2011.943

ROTILI D, MAI A. (2011). Targeting Histone Demethylases: A New Avenue for the Fight against Cancer. . GENES & CANCER; p. 663-679, ISSN: 1947-6019, doi: 10.1177/1947601911417976

Ferretti R, MAI A., Gallinella B, Zanitti L, Valente S, Cirilli R (2011). Application of 3 µm particle-based amylose-derived chiral stationary phases for the enantioseparation of potential histone deacetylase inhibitors. JOURNAL OF CHROMATOGRAPHY, vol. 1218, ISSN: 0021-9673, doi: 10.1016/j.chroma.2011.09.052

Rotili D, Tarantino D, Carafa V, Lara E, Meade S, Botta G, Nebbioso A, Schemies J, Jung M, Kazantsev AG, Esteller M, Fraga MF, Altucci L, MAI A. (2010). Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors. CHEMMEDCHEM; p. 674-677, ISSN: 1860-7187, doi: 10.1002/cmdc.201000030

Spallotta F, Rosati J, Straino S, Nanni S, Grasselli A, Ambrosino V, Rotili D, Valente S, Farsetti A, MAI A., Capogrossi MC, Gaetano C, Illi B. (2010). Nitric oxide determines mesodermic differentiation of mouse embryonic stem cells by activating class IIa histone deacetylases: potential therapeutic implications in a mouse model of hindlimb ischemia. STEM CELLS, ISSN: 1066-5099, doi: 10.1002/stem.300

Novakov IA, Orlinson B, Nawrozkij MB, MAI A., Artico M, Rotili D, Eremiychuk AS, Gordeeva EA, Brunilina LL, Este JA. (2010). The specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides. . CHEMISTRY OF HETEROCYCLIC COMPOUNDS, ISSN: 0009-3122, doi: 10.1007/s10593-010-0492-3

MAI A., Artico M, Rotili D, Novakov IA, Orlinson BS, Navrotskii MB, Eremiichuk AS, Gordeeva EA. (2009). Stereoselective synthesis of 2-substituted 6-[1-(2,6-difluorophenyl)ethyl]-5-methylpyrimidin-4(3H)-ones. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY; p. 1531-1534, ISSN: 1070-4280, doi: 10.1134/S1070428009100194

Novakov IA, Orlinson BS, MAI A., Artico M, Rotili D, Navrotskii MB, Gordeeva EA, Savel'ev EN. (2009). Reactions of 6-benzyl-5-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-one with aliphatic and aliphatic-aromatic amines. . RUSSIAN JOURNAL OF ORGANIC CHEMISTRY; p. 773-776, ISSN: 1070-4280, doi: 10.1134/S1070428009050212

Rotili D, Samuele A, Tarantino D, Ragno R, Musmuca I, Ballante F, Botta G, Morera L, Pierini M, Cirilli R, Nawrozkij MB, Gonzalez E, Clotet B, Artico M, Esté JA, Maga G, MAI A. (2012). 2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55; p. 3558-3562, ISSN: 1520-4804, doi: 10.1021/jm201308v

CARRADORI S., SECCI D., MAI A. (2011). EPIGENETIC MODULATION OF PGC-1a ACTIVITY BY GCN5 INHIBITORS: WO2010007085. EXPERT OPINION ON THERAPEUTIC PATENTS, vol. 21; p. 1651-1656, ISSN: 1354-3776, doi: 10.1517/13543776 2011.602069

Sergio Valente, Ilaria lepore, Carmela Dell'Aversa, Maria Tardugno, Sabrina Castellano, Gianluca Sbardella, Stefano Tomassi, Salvatore Di Maro, Ettore Novellino, Roberto Di Santo, Roberta Costi, Lucia Altucci, MAI A. (2012). Identification of PR-SET7 and EZH2 selective inhibitors inducing cell death in human leukemia U937 cells. BIOCHIMIE, vol. 94; p. 2308-2313, ISSN: 0300-9084, doi: 10.1016/j.biochi2012.06.003

Laura Silvestri, Flavio Ballante, MAI A., Garland R. Marshall, Rino Ragno (2012). Histone Deacetylase Inhibitors: Structure-Based Modeling and Isoform-Selectivity Prediction. JOURNAL OF CHEMICAL INFORMATION AND MODELING, vol. 52; p. 2215-2235, ISSN: 1549-9596, doi: 10.1021/ci300160y

Rotili D, Tarantino D, Carafa V, Paolini C, Schemies J, Jung M, Botta G, Di Maro S, Novellino E, Steinkühler C, De Maria R, Gallinari P, Altucci L, MAI A. (2012). Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55; p. 8193-8197, ISSN: 0022-2623

Wei W, Coelho CM, Li X, Marek R, Yan S, Anderson S, Meyers D, Mukherjee C, Sbardella G, Castellano S, Milite C, Rotili D, MAI A., Cole PA, Sah P, Kobor MS, Bredy TW. (2012). p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear. THE JOURNAL OF NEUROSCIENCE, ISSN: 0270-6474

Rotili D, Tarantino D, Carafa V, Paolini C, Schemies J, Jung M, Botta G, Di Maro S, Novellino E, Steinkühler C, De Maria R, Gallinari P, Altucci L, MAI A. (2012). Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells. JOURNAL OF MEDICINAL CHEMISTRY, vol. 55; p. 8193-8197, ISSN: 0022-2623, doi: 10.1021/jm301115r

Wei W, Coelho CM, Li X, Marek R, Yan S, Anderson S, Meyers D, Mukherjee C, Sbardella G, Castellano S, Milite C, Rotili D, MAI A., Cole PA, Sah P, Kobor MS, Bredy TW (2012). p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear. THE JOURNAL OF NEUROSCIENCE, vol. 32; p. 11930-11941, ISSN: 0270-6474, doi: 10.1523/JNEUROSCI.0178-12.2012

Galmozzi A, Mitro N, Ferrari A, Gers E, Gilardi F, Godio C, Cermenati G, Gualerzi A, Donetti E, Rotili D, Valente S, Guerrini U, Caruso D, MAI A., Saez E, De Fabiani E, Crestani M (2012). Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue. DIABETES, ISSN: 0012-1797, doi: 10.2337/db12-0548

Colussi C, Scopece A, Vitale S, Spallotta F, Mattiussi S, Rosati J, Illi B, MAI A., Castellano S, Sbardella G, Farsetti A, Capogrossi MC, Gaetano C (2012). P300/CBP Associated Factor Regulates Nitroglycerin-Dependent Arterial Relaxation by N{varepsilon}-Lysine Acetylation of Contractile Proteins. ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY, vol. 32; p. 2435-2443, ISSN: 1079-5642, doi: 10.1161/ATVBAHA.112.254011

Palmisano I, Della Chiara G, D'Ambrosio RL, Huichalaf C, Brambilla P, Corbetta S, Riba M, Piccirillo R, Valente S, Casari G, MAI A., Martinelli Boneschi F, Gabellini D, Poli G, Schiaffino MV (2012). Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 109; p. E2284-E2293, ISSN: 0027-8424, doi: 10.1073/pnas.1202174109

Michele M. Maxwell, Julien Francisco Zaldivar-Jolissaint, MAI A., Tiago F. Outeiro, Aleksey G. Kazanstev (2012). Highlights of the Keystone Symposium: sirtuins in metabolism, aging and disease. EMBO MOLECULAR MEDICINE, vol. 4; p. 557-560, ISSN: 1757-4676, doi: 10.1002/emmm.201201452

David Adams, Lucia Altucci, Stylianos E Antonarakis, Juan Ballesteros, Stephan Beck, Adrian Bird, Christoph Bock, Bernhard Boehm, Elias Campo, Andrea Caricasole, Fredrik Dahl, Emmanouil T Dermitzakis, Tariq Enver, Manel Esteller, Xavier Estivill, Anne Ferguson-Smith, Jude Fitzgibbon, Paul Flicek, Claudia Giehl, Thomas Graf, Frank Grosveld, Roderic Guigo, Ivo Gut, Kristian Helin, Jonas Jarvius, Ralf Küppers, Hans Lehrach, Thomas Lengauer, Åke Lernmark, David Leslie, Markus Loeffler, Elizabeth Macintyre, MAI A., Joost HA Martens, Saverio Minucci, Willem H Ouwehand, Pier Giuseppe Pelicci, Hèléne Pendeville, Bo Porse, Vardhman Rakyan, Wolf Reik, Martin Schrappe, Dirk Schübeler, Martin Seifert, Reiner Siebert, David Simmons, Nicole Soranzo, Salvatore Spicuglia, Michael Stratton, Hendrik G Stunnenberg, Amos Tanay, David Torrents, Alfonso Valencia, Edo Vellenga, Martin Vingron, Jörn Walter, Spike Willcocks (2012). BLUEPRINT to decode the epigenetic signature written in blood. NATURE BIOTECHNOLOGY, vol. 30; p. 224-226, ISSN: 1087-0156, doi: 10.1038/nbt.2153

Cencioni, C.; Spallotta, F.; Martelli, F.; Valente, S.; Mai, A.; Zeiher, A. M.; Gaetano, C. Oxidative stress and epigenetic regulation in ageing and age-related diseases. Int J Mol Sci 2013, 14, 17643-63.

Mellini, P.; Kokkola, T.; Suuronen, T.; Salo, H. S.; Tolvanen, L.; Mai, A.; Lahtela-Kakkonen, M.; Jarho, E. M. Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells. J Med Chem 2013, 56, 6681-95.

Crea, F.; Clermont, P. L.; Mai, A.; Helgason, C. D. Histone modifications, stem cells and prostate cancer. Curr Pharm Des 2013 Jul 19. [Epub ahead of print]

Spallotta, F.; Tardivo, S.; Nanni, S.; Rosati, J. D.; Straino, S.; Mai, A.; Vecellio, M.; Valente, S.; Capogrossi, M. C.; Farsetti, A.; Martone, J.; Bozzoni, I.; Pontecorvi, A.; Gaetano, C.; Colussi, C. Detrimental effect of class-selective histone deacetylase inhibitors during tissue regeneration following hindlimb ischemia. J Biol Chem 2013, 288, 22915-29.

Tortorici, M.; Borrello, M. T.; Tardugno, M.; Chiarelli, L. R.; Pilotto, S.; Ciossani, G.; Vellore, N. A.; Bailey, S. G.; Cowan, J.; O'Connell, M.; Crabb, S. J.; Packham, G.; Mai, A.; Baron, R.; Ganesan, A.; Mattevi, A. Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase. ACS Chem Biol 2013, 8, 1677-1682.

Valente, S.; Trisciuoglio, D.; Tardugno, M.; Benedetti, R.; Labella, D.; Secci, D.; Mercurio, C.; Boggio, R.; Tomassi, S.; Di Maro, S.; Novellino, E.; Altucci, L.; Del Bufalo, D.; Mai, A.; Cosconati, S. tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells. ChemMedChem 2013, 8, 800-811.

Spallotta, F.; Cencioni, C.; Straino, S.; Nanni, S.; Rosati, J.; Artuso, S.; Manni, I., Colussi, C.; Piaggio G.; Martelli, F.; Valente, S.; Mai, A.; Capogrossi, M. C.; Farsetti, A.; Gaetano, C. A Nitric Oxide-dependent Crosstalk Between Class I and III Histone Deacetylases Accelerates Skin Repair. J. Biol. Chem. 2013, 288, 11004-11012.

Mannaerts, I.; Eysackers, N.; Onyema, O. O.; Van Beneden, K.; Valente, S.; Mai, A.; Odenthal, M.; van Grunsven, L. A. Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29. PLoS One 2013, 8,e55786.

Galmozzi, A.; Mitro, N.; Ferrari, A.; Gers, E.; Gilardi, F.; Godio, C.; Cermenati, G.; Gualerzi, A.; Donetti, E.; Rotili, D.; Valente, S.; Guerrini, U.; Caruso, D.; Mai, A.; Saez, E.; De Fabiani, E.; Crestani, M. Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue. Diabetes 2013, 62, 732-742.

13.: MARIANECCI CARLOTTA

Simona Sennato, Federico Bordi, Cesare Cametti, Carlotta Marianecci, Maria Carafa, Massimo Cametti. “Hybrid niosome complexation in the presence of oppositely charged polyions”. Journal of Physical Chemistry B (2008), 112 (12), 3720, ISSN 1520-6106

M. Carafa, C. Marianecci, M. Salvatorelli, L. Di Marzio, F. Cerreto, G. Lucania, E. Santucci. “ Formulation of retinyl palmitate included in solid lipid nanoparticles: characterization and influence on light-induced vitamin degradation”. Journal of Drug Delivery Science and Technology, (2008), 18 (2), 119, ISSN1773-2247

Ruggero Caminiti, Giulio Caracciolo, Daniela Pozzi, Carlotta Marianecci, Simone Moglioni, Maria Carafa and Heinz Amenitsch. ”Effect of hydration on the structure of solid-supported Niosomal membranes investigated by in situ Energy Dispersive X-ray Diffraction”. Chemical Physics Letters, (2008), 462 (4-6), 307, ISSN 0009-2614

Di Marzio Luisa, Marianecci Carlotta, Cinque Benedetta, Nazzarri Maria, Cimini Anna Maria, Cristiano Loredana, Cifone Maria Grazia, Alhaique Franco, Carafa Maria “pH-sensitive non-phospholipid vesicle and macrophagic cells: binding, uptake and endocytotic pathway” Biochimica et Biophysica Acta Biomembranes (2008) Volume 1778, Issue 12, Pages 2749-2756, ISSN 0005-2736

Patrizia Paolicelli, Felice Cerreto, Stefania Cesa, Michelle Feeney, Federica Corrente, Carlotta Marianecci & Maria Antonietta Casadei “Influence of the formulation components on the properties of the system SLN-dextran hydrogel for the modified release of drugs” Journal of Microencapsulation (2008), ISSN0265-2048, DOI 0.1080/02652040802372899

Cristina Marchini, Maura Montani, Augusto Amici, Heinz Amenitsch, Carlotta Marianecci, Daniela Pozzi, and Giulio Caracciolo “Structural Stability and Increase in Size rationalize the efficiency of lipoplexes in serum” Langmuir, (2009), 25 (5), 3013-3021 ISSN 0743-7463

Carafa M, Marianecci C, Rinaldi F, Santucci E, Tampucci S, Monti D “Span and Tween neutral and pH-sensitive vesicles: characterization and in vitro skin permeation”. J Liposome Res. (2009);19(4):332-40.PMID: 19863168

D. Pozzi, R. Caminiti, G. Caracciolo, C. Marianecci, M. Carafa, E. Santucci “Effect of cholesterol on the structure of phospholipids and non-phospholipid membranes” Eur Biophys J (2009) 38 (Suppl 1): S193

Carafa M, Marianecci C, Marzio LD, Caro VD, Giandalia G, Giannola LI, Santucci E. “Potential dopamine prodrug-loaded liposomes: preparation, characterization, and in vitro stability studies”. J Liposome Res. (2010) 20 (3), pp. 250-257 DOI: 10.3109/08982100903014994

Pozzi D, Caminiti R, Marianecci C, Carafa M, Santucci E, De Sanctis SC, Caracciolo G. Effect of cholesterol on the formation and hydration behavior of solid-supported niosomal membranes. Langmuir. (2010) 26(4):2268-73.PMID: 19761205 ISSN 0743-7463

Carlotta Marianecci; Donatella Paolino; Christian Celia ; Massimo Fresta; Maria Carafa; Franco Alhaique “Non-ionic Surfactant Vesicles, Beclomethasone Dipropionate, Pulmonary Drug Carrier, Primary Human Lung Fibroblasts, Carrier-cell interaction, Anti-inflammatory activity” Journal of Controlled Release (2010) 147 pp.127-135

Daniela Pozzi, Carlotta Marianecci, Maria Carafa, Cristina Marchini, Maura Montani, Augusto Amici, Giulio Caracciolo “Programmed packaging of multicomponent envelopetype nanoparticle system for gene delivery” APPLIED PHYSICS LETTERS (2010) 96, 183702

Andrea Masotti, Paola Vicennati, Anna Alisi, Carlotta Marianecci, Federica Rinaldi, Maria Carafa, Giancarlo Ortaggi “Novel Tween® 20 derivatives enable the formation of efficient pH-sensitive drug delivery vehicles for human hepatoblastoma” Bioorganic & Medicinal Chemistry Letters (2010) Volume 20, Issue 10, Pages 3021-3025

Luisa Di Marzio, Carlotta Marianecci, Mariadea Petrone, Federica Rinaldi, Maria Carafa "Novel pH-sensitive non-ionic surfactant vesicles: comparison between Tween 21 and Tween 20" Colloids and Surface B: Biointerfaces, (2011), 82, 1824

Amenitsch, H., Caracciolo, G., Foglia, P., Fuscoletti, V., Giansanti, P. , Marianecci C., Pozzi, D.,Laganà, A. "Existence of hybrid structures in cationic liposome/DNA complexes revealed by their interaction with plasma proteins" Colloids and Surface B: Biointerfaces (2011), 82 (1), 141-146

Agrati, C. , Marianecci, C. , Sennato, S. , Carafa M., Bordoni, V. , Cimini, E. , Tempestilli, M. , Pucillo, L.P. , Turchi, F. , Martini, F. , Borioni, G. , Bordi, F. "Multicompartment vectors as novel drug delivery systems: Selective activation of Tγδ lymphocytes after zoledronic acid delivery". Nanomedicine: Nanotechnology, Biology, and Medicine, (2011), 7, 153-161

Giulio Caracciolo,Daniela Pozzi,Anna Laura Capriotti,Carlotta Marianecci, Maria Carafa, Cristina Marchini, Maura Montani, Augusto Amici, Heinz Amenitsch, Michelle A. Digman, Enrico Gratton, Susana S. Sanchez, and Aldo Laganà. "Factors Determining the Superior Performance of Lipid/DNA/Protammine Nanoparticles over Lipoplexes" Journal of Medicinal Chemistry, (2011), 54 (12), 4160-4171

Carlotta Marianecci, Maria Carafa, Luisa Di Marzio, Federica Rinaldi, Chiara Di Meo, Franco Alhaique, Pietro Matricardi, Tommasina Coviello. "A New Vesicle-loaded Hydrogel System Suitable for Topical Applications: Preparation and Characterization" J Pharm Pharmaceut Sci (www.cspsCanada.org), (2011), 14(3), 336 - 346

Carlotta Marianecci, Luisa Di Marzio, Federica Rinaldi , Maria Carafa, Franco Alhaique "Pulmonary delivery: innovative approaches and perspectives" Journal of Biomaterials and Nanobiotechnology (www.scirp.org/journal/jbnb) 2011, 2, 567-575 ISSN Print: 2158-7027 ISSN Online: 2158-7043 doi:10.4236/jbnb.2011.225068

Luisa Di Marzio, Carlotta Marianecci, Federica Rinaldi, Sara Esposito and Maria Carafa "Deformable Surfactant Vesicles Loading Ammonium Glycyrrhizinate: Characterization and In Vitro Permeation Studies" Letters in Drug Design & Discovery, 2012, 9, 1-6

Carlotta Marianecci; Federica Rinaldi; Marica Mastriota; Stefano Pieretti; Elena Trapasso; Donatella Paolino; Maria Carafa "Anti-inflammatory activity of novel ammonium glycyrrhizinate/niosomes delivery system: human and murine models" J. Control. Release 2012, 164 (1) 17-25

C. Marianecci, F. Rinaldi, C. Ingallina, D. Passeri, A. Sorbo, M. Rossi and M. Carafa “Smart magnetic nanovesicles for theranostic application: preparation and characterization” IL NUOVO CIMENTO 2013, Vol. 36 C (2), 103-110

Carlotta Marianecci, Federica Rinaldi, Luisa Di Marzio, Daniela Pozzi, Giulio Caracciolo, Daniela Manno, Luciana Dini, Donatella Paolino, Christian Celia, Maria Carafa” Interaction of pH-sensitive non-phospholipid liposomes with cellular mimetic membranes” Biomed Microdevices (2013) 15:299–309 DOI 10.1007/s10544-012-9731-y

Stefano Coppola, Francesco Cardarelli, Daniela Pozzi, Laura C Estrada, Michelle A Digman, Enrico Gratton, Angelo Bifone, Carlotta Marianecci & Giulio Caracciolo “The role of cytoskeleton networks on lipid-mediated delivery of DNA” Therapeutic Delivery (2013) 4(2), 191–202

Carlotta Marianecci, Federica Rinaldi, Luisa Di Marzio, Alessia Ciogli, Sara Esposito and Maria Carafa “Polysorbate 20 vesicles as multi-drug carriers: in vitro preliminary evaluations” Letters in Drug Design & Discovery (2013) 10, 212-218

Carlotta Marianecci, Federica Rinaldi, Sara Esposito, Luisa Di Marzio and Maria Carafa “Niosomes Encapsulating Ibuprofen–Cyclodextrin Complexes: Preparation and Characterization” Current Drug Targets (2013), 14, 1070-1078

Passeri D, Dong C, Angeloni L, Pantanella F, Natalizi T, Berlutti F, Marianecci C, Ciccarello F, Rossi M. “Thickness measurement of soft thin films on periodically patterned magnetic substrates by phase difference magnetic force microscopy” Ultramicroscopy (2013); 136C:96106. doi:10.1016/j.ultramic.2013.08.001.

14.: MAZZEI Franco

DELLE NOCI S, FRASCONI M, FAVERO G, TOSI M, T. FERRI, MAZZEI F. (2008). Electrochemical kinetic characterization of redox mediated Glucose Oxidase reactions: a simplified approach. ELECTROANALYSIS, vol. 20; p. 163-169, ISSN: 1040-0397, doi: 10.1002/elan.200704030

ROMAGNOLI E, MASCIA ML, CIPRIANI C, FASSINO V, MAZZEI F., E. D'ERASMO, CARNEVALE V, SCILLITANI A, MINISOLA S (2008). Short and Long Term Variations in Serum Calciotrophic Hormones after a Single Very Large Dose of Ergocalciferol (Vitamin D2) or Cholecalciferol (Vitamin D3) in the Elderly. THE JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, vol. 93; p. 3015-3020, ISSN: 0021-972X, doi: 10.1210/jc.2008-0350

MAZZEI F., G. FAVERO, FRASCONI M, TATA A, TUCCITTO N, LICCIARDELLO A, PEPI F (2008). Soft-landed Protein Voltammetry: a new tool for redox protein characterization. ANALYTICAL CHEMISTRY, vol. 80; p. 5937-5944, ISSN: 0003-2700, doi: 10.1021/ac8005389

FRASCONI M, G. FAVERO, DI FUSCO M, MAZZEI F. (2009). Polyazetidine-based Immobilization of Redox Proteins for Electron Transfer Based Biosensors. BIOSENSORS & BIOELECTRONICS, vol. 24; p. 1424-1430, ISSN: 0956-5663, doi: 10.1016/j.bios.2008.08.017

DERIU D, FAVERO G, D'ANNIBALE A, MAZZEI F. (2008). Study of Ferrocene-modified G4-PAMAM Dendrimer for Reagentless Biosensor Development. ECS TRANSACTIONS, vol. 16(11); p. 105-113, ISSN: 1938-5862, doi: 10.1149/1.2981110

MAZZEI F., BOTRÈ F, PODESTÀ E, G. FAVERO, BOTRÈ C (2009). Partially Disposable Biosensors for the Quick Assessment of Damage in Foodstuff after Thermal Treatment. MICROCHEMICAL JOURNAL, vol. 91; p. 209-213, ISSN: 0026-265X, doi: 10.1016/j.microc.2008.11.003

MAZZEI F., FAVERO G, FRASCONI M, TATA A, PEPI F (2009). Electron-Transfer Kinetics of Microperoxidase-11 Covalently Immobilised onto the Surface of Multi-Walled Carbon Nanotubes by Reactive Landing of Mass-Selected Ions. CHEMISTRY-A EUROPEAN JOURNAL, vol. 15; p. 7359-7367, ISSN: 0947-6539, doi: 10.1002/chem.200900887

FRASCONI M, MAZZEI F. (2009). Electrochemical and Surface Plasmon Resonance characterization of beta-cyclodextrin based self assembled monolayers and evaluation of their inclusion complexes with glucorticoids. NANOTECHNOLOGY, vol. 20; p. 285502-285509, ISSN: 0957-4484, doi: 10.1088/0957-4484/20/28/285502

FRASCONI M, REA S, MATRICARDI P, FAVERO G, MAZZEI F. (2009). Scleroglucan-Borax Hydrogel: a Flexible Tool for Redox Protein Immobilization. LANGMUIR, vol. 25 (18); p. 11097-11104, ISSN: 0743-7463, doi: 10.1021/la901245z

MAZZARINO M, DE LA TORRE X, MAZZEI F., BOTRÈ F (2009). Rapid screening of beta-adrenergic agents and related compounds in human urine for anti-doping purpose using capillary electrophoresis with dynamic coating. JOURNAL OF SEPARATION SCIENCE, vol. 32; p. 3562-3570, ISSN: 1615-9306, doi: 10.1002/jssc.200900450

FRASCONI M, FAVERO G, TORTOLINI C, MAZZEI F. (2009). Bioelectrochemical Characterization of Horseradish and Soybean peroxidases. ELECTROANALYSIS, vol. 21; p. 2378-2386, ISSN: 1040-0397, doi: 10.1002/elan.200900208

PETRUCCIOLI M, FRASCONI M, QUARATINO D, COVINO S, G. FAVERO, MAZZEI F., FEDERICI F, DANNIBALE A (2009). Kinetic and redox properties of MnP II, a major manganese peroxidase isoenzyme from Panus tigrinus CBS 577.79. JBIC, vol. 14; p. 1153-1163, ISSN: 0949-8257, doi: 10.1007/s00775-009-0559-8

FRASCONI M, D'ANNIBALE A, G. FAVERO, MAZZEI F., SANTUCCI R, FERRI T (2009). Ferrocenyl Alkanethiols-Thio beta-Cyclodextrin Mixed Self-Assembled Monolayers: Evidence of Ferrocene Electron Shuttling Through the beta-Cyclodextrin Cavity. LANGMUIR, vol. 25 ; p. 12937-12944, ISSN: 0743-7463, doi: 10.1021/la9018597

MARCO FRASCONI, MONICA MAZZARINO, FRANCESCO BOTRÈ, MAZZEI F. (2009). Surface plasmon resonance immunosensor for cortisol and cortisone determination. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 394; p. 2151-2159, ISSN: 1618-2642, doi: 10.1007/s00216-009-2914-6

A. D'ANNIBALE, DERIU D, FRASCONI M, MAZZEI F. (2009). Nanostructured materials based on the Integration of ferrocenyl-tethered dendrimer and redox proteins on self-assembled monolayers: An efficient biosensor interface. NANOTECHNOLOGY, vol. 20; p. 505501-505508, ISSN: 0957-4484, doi: 10.1088/0957-4484/20/50/505501

DI FUSCO M, TORTOLINI C, DERIU D, MAZZEI F. (2010). Laccase-Based Biosensor for the Determination of Polyphenol Index in Wine. TALANTA, vol. 81; p. 235-240, ISSN: 0039-9140, doi: 10.1016/j.talanta.2009.11.063

FRASCONI M, FAVERO G, BOER H, KOIVULA A, MAZZEI F. (2010). Kinetic and biochemical properties of high and low redox potential laccases from fungal and plant origin. BIOCHIMICA ET

BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, vol. 1804; p. 899-908, ISSN: 1570-9639, doi: 10.1016/j.bbapap.2009.12.018

FRASCONI M, MAZZEI F., T. FERRI (2010). Protein immobilisation at gold-thiol surfaces and potential for biosensing. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 398; p. 1545-1564, ISSN: 1618-2642, doi: 10.1007/s00216-010-3708-6

TORTOLINI C, DI FUSCO M, FRASCONI M, G. FAVERO, MAZZEI F. (2010). Laccase-Polyazetidine Prepolymer-MWCNT integrated system: Biochemical properties and application to analytical determinations in real samples. MICROCHEMICAL JOURNAL, vol. 96; p. 301-307, ISSN: 0026-265X, doi: 10.1016/j.microc.2010.05.004

MARCO FRASCONI, CRISTINA TORTOLINI, FRANCESCO BOTRE, MAZZEI F. (2010). Multifunctional Au Nanoparticle Dendrimer-Based Surface Plasmon Resonance Biosensor and Its Application for Improved Insulin Detection. ANALYTICAL CHEMISTRY, vol. 82; p. 7335-7342, ISSN: 0003-2700, doi: 10.1021/ac101319k

MARCO FRASCONI, HARRY BOER, ANU KOIVULA, MAZZEI F. (2010). Electrochemical evaluation of electron transfer kinetics of high and low redox potential laccases on gold electrode surface. ELECTROCHIMICA ACTA, vol. 56; p. 817-827, ISSN: 0013-4686, doi: 10.1016/j.electacta.2010.09.056

FABIO DOMENICI, MARCO FRASCONI, MAZZEI F., GABRIELLA DORAZI, ANNA RITA BIZZARRI AND SALVATORE CANNISTRARO (2011). Azurin modulates the association of Mdm2 with p53: an SPR evidence from interaction of the full-length proteins. JOURNAL OF MOLECULAR RECOGNITION, vol. 24; p. 707-714, ISSN: 0952-3499, doi: 10.1002/jmr.1105

FEDERICO PEPI, ALESSANDRA TATA, STEFANIA GARZOLI, PIERLUIGI GIACOMELLO, RINO RAGNO, ALEXANDROS PATSILINAKOS, MASSIMO DI FUSCO, ANDREA DANNIBALE, SALVATORE CANNISTRARO, CHIARA BALDACCHINI, GABRIELE FAVERO, MARCO FRASCONI, MAZZEI F. (2011). Chemically Modified Multiwalled Carbon Nanotubes Electrodes with Ferrocene Derivatives through Reactive Landing. JOURNAL OF PHYSICAL CHEMISTRY. C, NANOMATERIALS AND INTERFACES, vol. 115; p. 4863-4871, ISSN: 1932-7447, doi: 10.1021/jp1100472

CRISTINA TORTOLINI, MARCO FRASCONI, MASSIMO DI FUSCO, MAZZEI F. (2010). Surface plasmon resonance biosensors for environmental analysis: general aspects and applications. INTERNATIONAL JOURNAL OF ENVIRONMENT AND HEALTH, vol. 4; p. 305-322, ISSN: 1743-4955, doi: 10.1504/IJENVH.2010.037496

Marco Frasconi, Arnon Heyman, Izhar Medalsy, Danny Porath, MAZZEI F., Oded Shoseyov (2011). Wiring of Redox Enzymes on Three Dimensional Self-Assembled Molecular Scaffold. LANGMUIR, vol. 20; p. 12606-12613, ISSN: 0743-7463, doi: 10.1021/la2020435

Cristina Tortolini, Sara Rea, Eleonora Carota, Salvatore Cannistraro, MAZZEI F. (2012). Influence of the immobilization procedures on the electroanalytical performances of Trametes versicolor laccase based bioelectrode. MICROCHEMICAL JOURNAL, vol. 100; p. 8-13, ISSN: 0026-265X, doi: 10.1016/j.microc.2011.08.001

Marco Frasconi, Silvia Chichiarelli, Elisa Gaucci, MAZZEI F., Caterina Grillo, Alessandro Chinazzi, Fabio Altieri (2012). Interaction of ERp57 with calreticulin: Analysis of complex formation and effects of vancomycin. BIOPHYSICAL CHEMISTRY, vol. 1; p. 46-53, ISSN: 0301-4622, doi: 10.1016/j.bpc.2011.09.003

MASSIMO DI FUSCO, GABRIELE FAVERO, MAZZEI F. (2011). Polyazetidine-Coated Microelectrode: Electrochemical and Diffusion Characterization of Different Redox Substrates. JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL, vol. 115; p. 972-979, ISSN: 1520-6106, doi: 10.1021/jp107153c

MASSIMO DI FUSCO, RODOLFO FEDERICO, ALBERTO BOFFI, ALBERTO MACONE, GABRIELE FAVERO, MAZZEI F. (2011). Characterization and application of a Diamine Oxidase from Lathyrus sativus as Component of an Electrochemical Biosensor for the Determination of Biogenic Amines in wine and beer. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 401; p. 707-716, ISSN: 1618-2642, doi: 10.1007/s00216-011-5131-z

M. Frasconi, MAZZEI F. (2012). Electrochemically Controlled Assembly and Logic Gates Operations of Gold Nanoparticle Arrays via Supramolecular Coupling . LANGMUIR, vol. 6; p. 3322-3331, ISSN: 0743-7463, doi: 10.1021/la203985n

ANNARITA FIORILLO, RODOLFO FEDERICO, FABIO POLTICELLI, ALBERTO BOFFI, MAZZEI F., MASSIMO DI FUSCO, ANDREA ILARI, PARASKEVI TAVLODORAKI (2011). The structure of maize Polyamine Oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation. THE FEBS JOURNAL, vol. 278; p. 809-821, ISSN: 1742-464X, doi: 10.1111/j.1742-4658.2010.08000.x

Carlucci L., Favero G., Tortolini C., Di Fusco M., Romagnoli E., Minisola S., MAZZEI F. (in stampa). Several Approaches for Vitamin D Determination by Surface Plasmon Resonance and Electrochemical

Affinity Biosensors. BIOSENSORS & BIOELECTRONICS, ISSN: 0956-5663, doi: 10.1016/j.bios.2012.07.077

Carlucci L, Favero G, Tortolini C, Di Fusco M, Romagnoli E, Minisola S, Mazzei F.Several approaches for vitamin D determination by surface plasmon resonance and electrochemical affinity biosensors. Biosens Bioelectron. 2013 Feb 15;40(1):350-5. doi: 10.1016/j.bios.2012.07.077.

Tomassetti M, Martini E, Campanella L, Favero G, Carlucci L, Mazzei F. Comparison of three immunosensor methods (surface plasmon resonance, screen-printed and classical amperometric immunosensors) for immunoglobulin G determination in human serum and animal or powdered milks. J Pharm Biomed Anal. 2013 Jan 25;73:90-8. doi: 10.1016/j.jpba.2012.03.020.

15. MORERA Enrico

ORTAR GIORGIO, CASCIO MARIA GRAZIA, DE PETROCELLIS LUCIANO, MORERA E., ROSSI FRANCESCA, SCHIANO-MORIELLO ANIELLO, M. NALLI, DE NOVELLIS VITO, WOODWARD DAVID F, MAIONE SABATINO, DI MARZO VINCENZO (2007). New N-Arachidonoylserotonin Analogues with Potential 'Dual' Mechanism Action against Pain. JOURNAL OF MEDICINAL CHEMISTRY, vol. 50; p. 6554-6569, ISSN: 0022-2623, doi: 10.1021/jm070678q

G. ORTAR, CASCIO M.G, SCHIANO MORIELLO A, CAMALLI M, MORERA E., NALLI M, DI MARZO V (2008). Carbamoyl Tetrazoles as Inhibitors of Endocannabinoid Inactivation. A Critical Revisitation. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 43; p. 62-72, ISSN: 0223-5234, doi: 10.1016/j.ejmech.2007.02.023

G. ORTAR, A. SCHIANO MORIELLO, M. G. CASCIO, L. DE PETROCELLIS, A. LIGRESTI, MORERA E., M. NALLI, V. DI MARZO (2008). New tetrazole-based selective anandamide uptake inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 18; p. 2820-2824, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2008.04.003

G. ORTAR, T. BISOGNO, A. LIGRESTI, MORERA E., M. NALLI, V. DI MARZO (2008). Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism. JOURNAL OF MEDICINAL CHEMISTRY, vol. 51; p. 6970-6979, ISSN: 0022-2623, doi: 10.1021/jm800978m

S. MAIONE, MORERA E., I. MARABESE, A. LIGRESTI, L. LUONGO, G. ORTAR, V. DI MARZO (2008). Antinociceptive Effects of Tetrazole Inhibitors of Endocannabinoid Inactivation: Cannabinoid and Non-cannabinoid Receptor-mediated Mechanisms. BRITISH JOURNAL OF PHARMACOLOGY, vol. 155; p. 775-782, ISSN: 0007-1188, doi: 10.1038/bjp.2008.308

BISOGNO T, G. ORTAR, PETROSINO S, MORERA E., PALAZZO E, NALLI M, MAIONE S, DI MARZO V (2009). Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, vol. 1791; p. 53-60, ISSN: 1388-1981, doi: 10.1016/j.bbalip.2008.10.007

ULF-PETER APFEL, CHRISTIAN R. KOWOL, YVONNE HALPIN, FLORIAN KLOSS, JOACHIM KÜBEL, HELMAR GÖRLS, JOHANNES G. VOS, BERNHARD K. KEPPLER, MORERA E., GINO LUCENTE, WOLFGANG WEIGAND (2009). Investigation of amino acid containing [FeFe] hydrogenase models concerning pendant base effects. JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 103; p. 1236-1244., ISSN: 0162-0134, doi: 10.1016/j.jinorgbio.2009.07.005

MORERA E., LUCIANO DE PETROCELLIS, L. MORERA, ANIELLO SCHIANO MORIELLO, ALESSIA LIGRESTI, MARIANNA NALLI, DAVID F. WOODWARD, VINCENZO DI MARZO, GIORGIO ORTAR (2009). Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 19; p. 6806-6809, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2009.09.033

GIORGIO ORTAR, LUCIANO DE PETROCELLIS, L. MORERA, ANIELLO SCHIANO MORIELLO, PIERANGELO ORLANDO, MORERA E., MARIANNA NALLI, VINCENZO DI MARZO (2010). (-)Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20; p. 2729-2732, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2010.03.076

ULF-PETER APFEL, CHRISTIAN R. KOWOL, MORERA E., HELMAR GÖRLS, GINO LUCENTE, BERNHARD K. KEPPLER, WOLFGANG WEIGAND (2010). Synthetic and Electrochemical Studies of [2Fe2S] Complexes Containing a 4-Amino-1,2-dithiolane-4-carboxylic Acid Moiety. EUROPEAN JOURNAL OF INORGANIC CHEMISTRY; p. 5079-5086, ISSN: 1434-1948, doi: 10.1002/ejic.201000619

CACCHI S, MORERA E., G. ORTAR (2011). Discussion Addendum for Palladium-Catalyzed Reduction of Vinyl Trifluoromethanesulfonates to Alkenes: Cholesta-3,5-diene. ORGANIC SYNTHESES, vol. 88; p. 260-290, ISSN: 0078-6209

MORERA E., L. De Petrocellis, L. Morera, A. Schiano Moriello, M. Nalli, V. Di Marzo, G. Ortar (2012). Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22; p. 1674-1677, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2011.12.113

G. Ortar, L. Morera, A. Schiano Moriello, MORERA E., M. Nalli, V. Di Marzo, L. De Petrocellis (2012). Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22; p. 3535-3539, ISSN: 0960-894X, doi: 10.1016/j.bmcl.2012.03.055

Ortar G, Schiano Moriello A, Morera E, Nalli M, Di Marzo V, De Petrocellis L. 3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5614-8. doi: 10.1016/j.bmcl.2013.08.039.

Maione S, Costa B, Piscitelli F, Morera E, De Chiaro M, Comelli F, Boccella S, Guida F, Verde R, Ortar G, Di Marzo V. Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics. Pharmacol Res. 2013 Oct;76:98-105. doi: 10.1016/j.phrs.2013.07.003.

Ortar G, Morera E, De Petrocellis L, Ligresti A, Schiano Moriello A, Morera L, Nalli M, Ragno R, Pirolli A, Di Marzo V. Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: modulation at the N-portion and distal phenyl ring. Eur J Med Chem. 2013 May;63:118-32. doi: 10.1016/j.ejmech.2013.02.005.

Ortar G, De Petrocellis L, Moriello AS, Allarà M, Morera E, Nalli M, Di Marzo V. Tetrahydro-β-carboline derivatives targeting fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channels. Bioorg Med Chem Lett. 2013 Jan 1;23(1):138-42. doi: 10.1016/j.bmcl.2012.10.137.

16. PIERINI Marco

F. GASPARRINI, PIERINI M., VILLANI C, FILIPPI A, SPERANZA M (2008). Induced-fit in the gas phase: conformational effects on the enantioselectivity of chiral tetra-amido macrocycles. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 130; p. 522-534, ISSN: 0002-7863, doi: 10.1021/ja073287+

W. CABRI, A. CIOGLI, I. D'ACQUARICA, M. DI MATTIA, B. GALLETTI, F. GASPARRINI, F. GIORGI, S. LALLI, PIERINI M., P. SIMONE (2008). On-column epimerization of dihydroartemisinin: An effective analytical approach to overcome the shortcomings of the International Pharmacopoeia monograph. JOURNAL OF CHROMATOGRAPHY. B, vol. 875; p. 180-191, ISSN: 1570-0232, doi: 10.1016/j.jchromb.2008.06.037

A. CIOGLI, A. DALLA CORT, F. GASPARRINI, L. LUNAZZI, L. MANDOLINI, A. MAZZANTI, C. PASQUINI, PIERINI M., L. SCHIAFFINO, F. YAFTEH MIHAN (2008). Enantiomerization of Chiral Uranyl-Salophen Complexes via Unprecedented Ligand Hemilability: Toward Configurationally Stable Derivatives. JOURNAL OF ORGANIC CHEMISTRY, vol. 73; p. 6108-6118, ISSN: 0022-3263, doi: 10.1021/jo800610f

G. SIANI, G. ANGELINI, P. DE MARIA, A. FONTANA, PIERINI M. (2008). Solvent effects on the rate of keto/enol interconversion of 2-nitrocyclohexanone. ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 6; p. 4236-4241, ISSN: 1477-0520, doi: 10.1039/b813011f

B. BOTTA, PIERINI M., G. DELLE MONACHE, D. SUBISSATI, F. SUBRIZI, G. ZAPPIA (2008). Synthesis of amino and ammonium resorcin[4]arenes as potential receptors. SYNTHESIS, vol. 13; p. 2110-2116, ISSN: 0039-7881, doi: 10.1055/s-2008-1067111

R. CIRILLI, R. COSTI, R. DI SANTO, F. GASPARRINI, F. LA TORRE, PIERINI M., G. SIANI (2009). A rational approach to predict and modulate stereolability of chiral alpha-substituted ketones. CHIRALITY, vol. 21; p. 24-34, ISSN: 0899-0042, doi: 10.1002/chir.20589

C. VILLANI, F. GASPARRINI, PIERINI M., S. LEVI MORTERA, I. D'ACQUARICA, A. CIOGLI, G. ZAPPIA (2009). Dynamic HPLC of stereolabile iron(II) complexes on chiral stationary phases. CHIRALITY, vol. 21; p. 97-103, ISSN: 0899-0042, doi: 10.1002/chir.20612

C. FRASCHETTI, PIERINI M., C. VILLANI, F. GASPARRINI, A. FILIPPI, M. SPERANZA (2009). Gas-phase structure and relative stability of proton-bound homo- and heterochiral clusters of tetra-amide macrocycles with amines. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, vol. 74; p. 275-297, ISSN: 0010-0765, doi: 10.1135/cccc2008155

R. CIRILLI, R. COSTI, R. DI SANTO, F. LA TORRE, PIERINI M., G. SIANI (2009). Perturbing Effects of Chiral Stationary Phase on Enantiomerization Second-Order Rate Constants Determined by Enantioselective Dynamic High-Performance Liquid Chromatography: A Practical Tool to Quantify the Accessible Acid and Basic Catalytic Sites Bonded on Chromatographic Supports. ANALYTICAL CHEMISTRY, vol. 81; p. 3560-3570, ISSN: 0003-2700, doi: 10.1021/ac802212s

G. CANCELLIERE, A. CIOGLI, I. D'ACQUARICA, F. GASPARRINI, J. KOCERGIN, D. MISITI, PIERINI M., H. RITCHIE, P. SIMONE, C. VILLANI (2010). Transition from enantioselective high performance to ultra-high performance liquid chromatography: A case study of a brush-type chiral stationary phase based on sub-5-micron to sub-2-micron silica particles. JOURNAL OF CHROMATOGRAPHY A, vol. 1217; p. 990-999, ISSN: 0021-9673, doi: 10.1016/j.chroma.2009.10.021

I. D'ACQUARICA, F. GASPARRINI, D. KOTONI, PIERINI M., C. VILLANI, W. CABRI, M. DI MATTIA, F. GIORGI (2010). Stereodynamic Investigation of Labile Stereogenic Centres in Dihydroartemisinin. MOLECULES, vol. 15; p. 1309-1323, ISSN: 1420-3049, doi: 10.3390/molecules15031309

G. ANGELINI, P. DE MARIA, C. CHIAPPE, A. FONTANA, PIERINI M., G. SIANI (2010). Basicity of Pyridine and Some Substituted Pyridines in Ionic Liquids. JOURNAL OF ORGANIC CHEMISTRY, vol. 75; p. 3912-3915, ISSN: 0022-3263, doi: 10.1021/jo100570x

F. SANNICOLÒ, S. RIZZO, T. BENINCORI, W. KUTNER, K. NOWORYTA, J. W. SOBCZAK, V. BONOMETTI, L. FALCIOLA, P. R. MUSSINI, PIERINI M. (2010). An effective multipurpose building block for 3D electropolymerisation: 2,2’-bis(2,2’-bithiophene-5-yl)-3,3’-bithianaphthene. ELECTROCHIMICA ACTA, vol. 55; p. 8352-8364, ISSN: 0013-4686, doi: 10.1016/j.electacta.2010.04.070

C. FRASCHETTI, PIERINI M., C. VILLANI, F. GASPARRINI, S. LEVI MORTERA, M. SPERANZA (2009). Towards enzyme-like enantioselectivity in the gas phase: conformational control of selectivity in chiral macrocylic dimers. CHEMICAL COMMUNICATIONS, vol. 36; p. 5430-5432, ISSN: 1359-7345, doi: 10.1039/b909017g

Cirilli R., Ferretti R., La Regina G, Morelli G., PIERINI M., Piscitelli F., Silvestri R. (2010). Enantioselective HPLC combined with spectroscopic methods: a valid strategy to determine the absolute configuration of potential beta-secretase inhibitors. TALANTA, vol. 82; p. 1306-1312, ISSN: 0039-9140, doi: 10.1016/j.talanta.2010.06.060

L. LUNAZZI, M. MANCINELLI, A. MAZZANTI, PIERINI M. (2010). Stereomutation of Axially Chiral Aryl Coumarines. JOURNAL OF ORGANIC CHEMISTRY, vol. 75; p. 5927-5933, ISSN: 0022-3263, doi: 10.1021/jo101261k

G. Uccello-Barretta, F. Balzano, J. Martinelli, F. Gasparrini, PIERINI M., C. Villani (2011). NMR and Computational Investigations of the Chiral Discrimination Processes Involving a Cyclic Tetraamidic Chiral Selector. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; p. 3738-3747, ISSN: 1434-193X, doi: 10.1002/ejoc.201100408

A. Ciogli, A. Fontana, F. Gasparrini, M. Maggini, M. Giovannoli, PIERINI M., F. Busolo, G. Siani, C. Villani (2012). Inductive and mesomeric effects of the [60]fulleropyrrolidine fragment and [60]fullerene sphere: a quantitative evaluation based on theory and experiments. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; p. 193-202, ISSN: 1434-193X, doi: 10.1002/ejoc.201100997

C. FRASCHETTI, PIERINI M., C. VILLANI, F. GASPARRINI, S. LEVI MORTERA, A. FILIPPI, M. SPERANZA (2011). The "Bridge" Game: Role of the Fourth Player in Chiral Recognition. CHEMISTRY-A EUROPEAN JOURNAL, vol. 17; p. 3078-3081, ISSN: 0947-6539, doi: 10.1002/chem.201002828

W. Cabri, I. D'Acquarica, P. Simone, M. Di Iorio, M. Di Mattia, F. Gasparrini, F. Giorgi, A. Mazzanti, PIERINI M., M. Quaglia, C Villani (2011). Stereolability of Dihydroartemisinin, an Antimalarial Drug: A Comprehensive Kinetic Investigation. Part 2. JOURNAL OF ORGANIC CHEMISTRY, vol. 76; p. 4831-4840, ISSN: 0022-3263, doi: 10.1021/jo102392p

W. CABRI, I. D'ACQUARICA, P. SIMONE, M. DI IORIO, M. DI MATTIA, F. GASPARRINI, F. GIORGI, A. MAZZANTI, PIERINI M., M. QUAGLIA, C. VILLANI (2011). Stereolability of dihydroartemisinin, an antimalarial drug: a comprehensive thermodynamic investigation – Part 1. JOURNAL OF ORGANIC CHEMISTRY, vol. 76; p. 1751-1758, ISSN: 0022-3263, doi: 10.1021/jo102391s

E. BADALONI, M. BARBARINO, W. CABRI W, I. D'ACQUARICA, M. FORTE, F. GASPARRINI, F. GIORGI, PIERINI M., P. SIMONE, O. URSINI, C. VILLANI (2011). Efficient organic monoliths prepared by gamma-radiation induced polymerization in the evaluation of histone deacetylase inhibitors by capillary(nano)-high performance liquid chromatography and ion trap mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, vol. 1218; p. 3862-3875, ISSN: 0021-9673, doi: 10.1016/j.chroma.2011.04.048

R. BERNINI, F. CRISANTE, P. GENTILI, F. MORANA, PIERINI M., M. PIRAS (2011). Chemoselective C-4 Aerobic Oxidation of Catechin Derivatives Catalyzed by the Trametes villosa Laccase/1-Hydroxybenzotriazole System: Synthetic and Mechanistic Aspects. JOURNAL OF ORGANIC CHEMISTRY, vol. 76; p. 820-832, ISSN: 0022-3263, doi: 10.1021/jo101886s

G. Angelini, C. Coletti, P. De Maria, R. Ballini, C. Gasbarri, A. Fontana, PIERINI M., G. Siani (2012). Effect of Ring Size on the Tautomerization and Ionization Reaction of Cyclic 2- Nitroalkanones: An

Experimental and Theoretical Study. JOURNAL OF ORGANIC CHEMISTRY, vol. 77; p. 899-907, ISSN: 0022-3263, doi: 10.1021/jo202065h

S. Levi Mortera, R. Sabia, PIERINI M., F. Gasparrini, C. Villani (2012). The dynamic chromatographic behavior of tri-O-thymotide on HPLC chiral stationary phases. CHEMICAL COMMUNICATIONS; p. 3167-3169, ISSN: 1359-7345, doi: 10.1039/C2CC00021K

Rotili D, Samuele A, Tarantino D, Ragno R, Musmuca I, Ballante F, Botta G, Morera L, PIERINI M., Cirilli R, Nawrozkij MB, Gonzalez E, Clotet B, Artico M, Esté JA, Maga G, Mai A. (2012). 2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies. JOURNAL OF MEDICINAL CHEMISTRY; p. 3558-3562, ISSN: 1520-4804, doi: 10.1021/jm201308v

Domenico Misiti, Francesco Gasparrini, Ilaria D'Acquarica, Claudio Villani, PIERINI M. (2008). HPLC chiral stationary phases containing macrocyclic antibiotics: practical aspects and recognition mechanism . ADVANCES IN CHROMATOGRAPHY, vol. 46; p. 108-173, ISSN: 0065-2415

Ghirga F, D'Acquarica I, Delle Monache G, Mannina L, Molinaro C, Nevola L, Sobolev AP,Pierini M, Botta B.Reaction of nitrosonium cation with resorc[4]arenes activated by supramolecular control: covalent bond formation. 2013 Jul 19;78(14):6935-46. doi: 10.1021/jo400489m.

Ciogli A, Kotoni D, Gasparrini F, Pierini M, Villani C. Chiral Supramolecular Selectors for Enantiomer Differentiation in Liquid Chromatography. Top Curr Chem. 2013 Jun 14.

Rizzo S, Benincori T, Bonometti V, Cirilli R, Mussini PR, Pierini M, Pilati T, Sannicolò F. Steric and electronic effects on the configurational stability of residual chiral phosphorus-centered three-bladed propellers: tris-aryl phosphanes. Chemistry. 2013 Jan 2;19(1):182-94. doi: 10.1002/chem.201201182. Epub 2012 Nov 20. Erratum in: Chemistry. 2013 Jan 2;19(1):21.

Benincori T, Bonometti V, Cirilli R, Mussini PR, Marchesi A, Pierini M, Pilati T, Rizzo S, Sannicolò F.Steric and electronic effects on the configurational stability of residual chiral phosphorus-centered three-bladed propellers: tris-aryl phosphane oxides. Chemistry. 2013 Jan 2;19(1):165-81. doi: 10.1002/chem.201201180.