Self-experimentation in

medicine

Notable examples of medical self-experimentation•ABO blood group•Cardiac catheterization•Thrombocytopenia•Helicobacter pylori•Cholera•Effects of forces on the body•Psychoactive drugs•Yellow fever•Alcohol•Heavy water•Neural implant•Skin transplant•Snake bite•Weight balance•Asthma•Bartonellosis

John Hunter

• one of the most distinguished scientists and surgeons of his day

• self-inoculation with gonorrhea and syphilis

• Jekyll & Hyde

1728-1793

Charles Byrne (8’ 1”)

1578-1657

William HarveyDiscoveries•Disproved Galen that blood not made from the liver•Heart is a pump not a suction device•Showed closed circuit circulation•Showed existence of valves in veins

drank choleric bacteria.

• miasma, noxious air associated with the air from rotting or fecal material

• Contagionists, disease caused by something that was catching, like smallpox or syphilis

Max von Pettenkofer1818-1901

Cardiac catheterization

Werner Forssmann 1930’s

• Won the Nobel Prize for medicine • Hospital administrators removed

him from his position owing to his unorthodox methods.

Barry Marshall

Helicobacter pyloriUlcer

Tim Friede

Snakebite & anti-venom

Black mambahttp://timfriede.com/

Craig VenterCelera Genomics

Disturbing Experiments

Disturbing Experiments

• Inter-species breeding (ape-man, Ilya Ivanovich Ivanov, Guinea, 1927)

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Disturbing Experiments

• Two-headed dog (Vladimir Petrovich Demikhov, 1950s, Russia)

http://www.youtube.com/watch?v=uvZThr3POlQ