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Seminar Series – Week Commencing 11 November 2019
Name of Presenter Title of Presentation Date Time Venue Further Information
Seminar Series
A/Prof Chris Blyth
& Dan Norman
Flu-prevention developing research - informed prevention programs
11 November 2019 12noon – 1pm Telethon Kids Institute Seminar Room, Level 5, Perth Children’s Hospital
CLICK HERE
Telethon Kids Institute &
Wesfarmers Centre of Vaccines & Infectious Diseases
Florian Busch, ANU
Photorespiration in the context of metabolism and anatomy
11 November 2019 12 noon Bayliss Building Lecture Theatre G33 CLICK
HERE
The Bayliss Seminar Series
Accelerating Child Health Research Distinguished Speakers include: Prof Bob Hancock Prof Scott Tebbutt Prof Jianguo (Jeff) Xia Prof Peter Gething Prof Pinaki Panigrahi
11 – 13 November 2019 - A Systems Biology Symposium Save the Date
Symposium Themes: Precision Health - Multi-omics applications - Systems epidemiology - Data integration & visualization Mon – Tues: - Speakers presentations Wed: - Interactive data workshops (numbers are limited)
Enquiries: [email protected]
Abstract Submissions: [email protected] (limited numbers selected, 300 word limit)
CLICK HERE
Respiratory Research Centre &
Centre for Personalised Medicine for Children
Pawsey Training on Scientific Workflow Tools
Nextflow lead developers: Paolo Di Tommaso & Evan Floden
11 – 14 November 2019 Nextflow Workshop and Hackathon at Pawsey: Comprehensive Nextflow Training: from Basics to Real User Cases
Watch this video to know what to expect during this session: https://www.youtube.com/watch?v=LG8Bwc69c58&feature=youtu.be
• Two days of workshop introduce the basic concepts and syntax of Nextflow• Two days of hackathon enable participants to apply Nextflow to a pipeline of their choice• By the end of the event, participants can confidently develop and deploy their own workflows using NextFlow,seeing increases in portability, reproducibility and scalability
CLICK LINK
Nextflow Workshop
Pawsey
Pawsey Supercomputing Centre
Registration essential – places limited:
Nextflow Workshop Pawsey (Discounted early-birds rates are
available through October 18)
UPCOMING SEMINARS
9 Barossa Meeting - Cell Signalling in Cancer Medicine Various International & National Speakers
12 – 15 November 2019 Conference Themes: Angiogenesis, apoptosis, cancer therapeutics, carcinogenesis, epithelial-mesenchymal transition, cancer genomics, immunotherapy, lipid signaling, metabolism, signaling networks, stem cells, translational medicine, tumour microenvironment, cellular plasticity/heterogeneity, therapy resistance
CLICK HERE
Centre for Cancer Biology
Philip Wijesinghe, SUPA, School of Physics and Astronomy – Uni of St Andrews, UK
Imaging across scales with light shaping in space and time
12 November 2019 12 noon – 1pm Seminar Room 272, Harry Perkins Institute of Medical Research, North Building
CLICK HERE
(includes map)
Perkins Seminar Series
Prof Cathryn Lewis, King’s College London
Using polygenic risk scores to predict risk of disease: hype, hope and statistical reality
12 November 2019 6pm Biological Sciences Lecture Theatre (240.2.05) Building 240 Murdoch Univeristy
CLICK HERE
Statistical Society of Australia WA Branch
A/Prof Rabindra Tirouvanziam
Mechanisms of inflammatory airway disease in cystic fibrosis: from models to patients
13 November 2019 12pm – 1pm Telethon Kids Institute Seminar Room Level 5, Perth Children’s Hospital
CLICK HERE
Telethon Kids Research Seminars
Prof Paul McMenamin, Monash Uni
The eye as a complex immune environment: an immunological window into the brain and meninges
13 November 2019 12.30pm – 1.30pm
(12pm for light lunch)
Curtin University, Kent Street, Bentley 201:322:LT
CLICK HERE
CHIRI Seminar Series
Raine Prof Mary Wlodek
Critical periods and lifestyle interventions programming development disease risk
14 November 2019 12pm – 1pm Bayliss Building Lecture Theatre G33
CLICK HERE
The Bayliss Seminar Series
Dr Shirley McGough, Curtin Uni
Qualitative Research Methods 15 November 2019 12.30pm – 1.30pm Perth Children’s Hospital, Level 5, PCH Auditorium
CLICK LINK
Qualitative Research Methods
Research Skills Seminar Series Research Education Program
Contact: [email protected]
a.gov.au
Mr Michael Phillips Development and evaluation of an artificial intelligence (AI) algorithm to detect malignant melanoma in smartphone images
15 November 2019 3pm 4th Floor Seminar Room, MRF Building, Rear 50 Murray Street, Perth
CLICK HERE
RPH Medical Research Forum Seminar Series 2019
Dr Kirsty Short Influenza in chronic disease patients: understanding the fundamentals to improve patient care
20 November 2019 12pm – 1pm Telethon Kids Institute Seminar Room Level 5, Perth Children’s Hospital
CLICK HERE
Telethon Kids Research Seminars
Prof W. Murray Thomson Editor-in-Chief - Community Dentistry and Oral Epidemiology, Assoc Editor - European Journal of Oral Sciences
Poor oral health casts a long shadow: findings from the Dunedin Study
20 November 2019 6pm Kenneth JG Sutherland Lecture Theatre, UWA Dental School, 17 Monash Ave, Nedlands
CLICK HERE
AJ Herman Fellowship Lecture UWA Dental School
RSVP mandatory by 5pm Tuesday 12
November: [email protected]
Australian Society for Medical Research National Scientific Conference
20 - 21 November 2019 - ASMR NSC 2019 Ebbs and Flows - From Discovery to Practice
Featuring:- Firkin Orator, Prof Daniel Drucker, Lunenfeld-Tanenbaum Research Institute, Toronto Edwards Orator, Prof Christobel Saunders AO, UWA & Royal Perth Hospital
For more information about registration & abstracts please click below: ASMR NSC 2019 Registration & Abstract
(Abstract submission deadline extended until 6 October 2019)
CLICK HERE
WA Maritime Museum Victoria Quay, Peter Hughes Dr,
Fremantle WA 6160
Maritime Museum Website http://museum.wa.gov.au/museums/
maritime/
A/Prof Sue Skull (CAHS)
Ethics Processes for Clinical Research in WA
22 November 2019 12.30 – 1.30pm Perth Children’s Hospital, Level 5, PCH Auditorium
CLICK LINK Ethics
Processes
Research Skills Seminar Series Research Education Program
Contact: researcheducationprogram@health.
wa.gov.au
Dr Christopher Minson Kenneth and Kenda Singer Professor
Heat therapy: An ancient practice to target modern diseases
27 November 2019 1pm John Bloomfield Lecture Theatre, UWA School of Human Sciences adjacent to Parkway Entrance 3.
Google Map Link Here
CLICK HERE
School of Human Sciences Seminar Series
Dr Riccardo Natoli, ANU
Blinded by the light: the role of miRNA in light induced retinal degenerations
28 November 2019 3pm Sarich Neuroscience Research Institute Building, Bryant Stokes Seminar Room, Ground Floor
CLICK HERE
The Bryant Stokes Neuroscience Seminar Series
Dr Daniel Green, UWA & Dr Louise Naylor, UWA
Exercise and Your Health Discover things you never knew about the health effects of exercise and learn how it benefits you across your lifespan at this FREE community health event
28 November 2019 1pm – 2pm The City of Perth Library’s Auditorium, 573 Hay St, Perth
CLICK HERE
RPH Research Foundation
The 6th Annual EMBL Australia Postgraduate Symposium (EAPS19)
27 – 29 November 2019 EAPS19 - From Models to Systems Deciphering Biological Complexity
Registrations Open – 10 June 2019 Registrations Close - 1 November 2019 Abstract Submissions Close – 6 September 2019
Meet interstate and international speakers and researches from various disciplines. Invited speakers:- Prof Christine Wells, (Uni Melbourne) Prof Nadia Rosenthal, (Jackson Laboratories USA) Dr Damien Bates, BioCurate Dr Chris Langmead, Monash Inst. of Pharmaceutical Sciences Dr Talitha Santini, UWA Dr Irene Gallego Romero, Uni Melbourne Prof Matt Sweet, Inst. of Molecular Bioscience, UQ Prof. Ricky W. Johnstone, Peter MacCallum Cancer Centre A/Prof Enzo Porrello, Murdoch Children’s Research Inst.
CLICK HERE
Victorian Comprehensive Cancer Centre, Melbourne
For more information & to register:
EAPS19
A/Prof Jasper Schipperijn
Changing the Built Environment changes children’s behavior
2 December 2019 3pm – 4pm Telethon Kids Institute Seminar Room Level 5, Perth Children’s Hospital
CLICK HERE
Telethon Kids Research Seminars
Nicole Sheers Airway clearance techniques: why, what, and when? A clinician-researcher’s approach
3 December 2019 12pm – 1pm The Conference Room, The Niche. 11 Aberdare Road, Nedlands
CLICK HERE
Telethon Kids Research Seminars
2020 SEMINARS
Mixomics Instructor: Dr Kim-Anh Lê Cao
3-5 February – Mixomics Beginner workshop for microbiome-omics data analysis More details on the attached flyer, we also have made a 50 min webinar available to present the different methods and their application: http://mixomics.org/2019/09/webinar-mixomics-in-50-minutes/
Four RHD student bursaries to cover 50% of the registration costs are generously supported by WAHTN. Register your interest here: Mixomics
CLICK HERE
WAHTN/WAHMCC
Human Genome Meeting 2020
5 – 8 April 2020 Perth Convention & Exhibition Centre Abstracts for the 24th Annual Human Genome Meeting in either Oral Presentation or Poster Presentation are invited - please submit to: HGM 2020 Abstracts Submission – Oral Abstract Submissions close Friday 10 January Midnight AWST Poster Abstract Submissions close Friday 7 February Midnight AWST
CLICK HERE
HUGO HGM 2020
Please click here for:
Registration
GAP 2020 - Global Academic Programs
11 -13 May 2020 MD Anderson Cancer Center Global Academic Programs is coming to Australia
Call for Abstracts is now open - Registration open 1 September 2019 - Sponsorship opportunities available
CLICK HERE
GAP 2020
To Register and for Abstract Submissions:
www.gap2020.com.au
MONDAY, 11 NOVEMBER 2019
12:00PM TO 1 :00PM
TELETHON KIDS INSTITUTE SEMINAR ROOM LEVEL 5, PERTH CHILDREN’S HOSPITAL
I N F E C T I O U S D I S E A S E S R E S E A R C H S E M I N A R
A / P R O F C H R I S B LY T HCo-Director, Wesfarmers Centre of Vaccines & Infectious Diseases
D A N N O R M A NPhD candidate, Infectious Diseases Epidemiology
Wesfarmers Centre HDR Scholarship Recipient
Flu-prevention: developing research- informed
prevent ion programs
THE BAYLISS SEMINAR SERIES
Presenter: Florian Busch – ANU
Title: Photorespiration in the context of metabolism and anatomy
Date: Monday 11 November 2019 @ 12 noon
Venue: Bayliss Building Lecture Theatre G33
If you have suggestions for speakers, please contact our seminar coordinators Nicole Smith [email protected] and Heng Chooi [email protected] with the details and to make arrangements for an invitation.
Accelerating Child Health Research A Systems Biology Symposium
Co-hosted by The Respiratory Research Centre & The Centre for Personalised Medicine for Children
11-13 November 2019
Auditorium, Perth Children’s Hospital
Monday & Tuesday: Speaker Presentations
Wednesday: Interactive Data Workshops (numbers are limited)
ABSTRACT SUBMISSIONSA limited number of oral presentations will be selected from submitted abstracts.
We strongly encourage early and mid career researchers to apply. If you wish to be considered, please submit your abstract (300 word limit)
[email protected]. Please note there will be no poster presentations at the Symposium.
Prof. Bob Hancock Canada Research Chair in Health and Genomics; Director, Centre for Microbial Diseases and Immunity Research, University of British Columbia
Prof. Scott Tebbutt Division of Respiratory Medicine, University of British Columbia; Centre for Heart Lung Innovation, St. Paul’s Hospital, Vancouver
Prof. Jianguo (Jeff) Xia Canada Research Chair in Bioinformatics and Big Data Analytics, McGill University, Canada
Prof. Peter Gething Kerry M Stokes Chair of Child Health, Telethon Kids Institute & Curtin University; Professor of Epidemiology, The Big Data Institute, University of Oxford
Prof. Jaap GoudsmitChief Scientific Officer, Human Vaccines Project; Prof. of Epidemiology, Harvard T.H. Chan School of Public Health; University of Amsterdam.
SYMPOSIUM THEMES
DISTINGUISHED SPEAKERS INCLUDE
THE RESPIRATORY RESEARCH CENTRE
Precision health
Multi-omics applications
Data integration & visualisation
Systems epidemiology
Enquiries:
Alex Beesley [email protected] Manzur [email protected]
REGISTER NOW
Cell Signalling in Cancer Medicine
International Speakers
Organising Committee
Program Committee
Centre forCancer Biology
International Advisory Committee Vishva Dixit, Richard Flavell, Wanjin Hong, Tony Hunter, Joseph Schlessinger, John D Scott
Program updates www.centreforcancerbiology.org.au
Yeesim Khew-Goodall and Stuart Pitson (Co-Convenors), Claudine Bonder, Angel Lopez, Michael Samuel, Hamish Scott
Claudine Bonder, Cameron Bracken, Susan Branford, Anna Brown, Michael Brown, Richard D’Andrea, Loretta Dorstyn, Guillermo Gomez,Phillip Gregory, Chris Hahn, Natasha Harvey, Sharad Kumar, Angel Lopez, Stuart Pitson, Jason Powell, Paul Reynolds, Nirmal Robinson, David Ross, Michael Samuel, Andreas Schreiber, Quenten Schwarz, Hamish Scott, Vinay Tergaonkar, Damon Tumes
Ivan Dikic Goethe University School of Medicine, Frankfurt, Germany Lucy Godley University of Chicago, IL, USA
Ming Lei Shanghai Jiao Tong University School of Medicine, China Shiva Malek Genentech, CA, USA
Madelon Maurice University Medical Center, Utrecht, Netherlands Gerry Melino University of Cambridge, UK
Erik Sahai Francis Crick Institute, London, UKTuomas Tammela Memorial Sloan Kettering Cancer Center, NY, USA
Wee Wei Tee Institute of Molecular and Cell Biology, SingaporeKaren Vousden Francis Crick Institute, London, UK
Conference Themes Angiogenesis, apoptosis, cancer therapeutics, carcinogenesis, epithelial-mesenchymaltransition, cancer genomics, immunotherapy, lipid signalling, metabolism, signalling networks, stem cells,translational medicine, tumour microenvironment, cellular plasticity / heterogeneity, therapy resistance
Marie-Liesse Assalin-Labat Walter and Eliza Hall Institute, VICKate Burbury Peter MacCallum Cancer Centre,VIC
Lisa Butler University of Adelaide, SAHMRI, SAThomas Cox Garvan Institute of Medical Research, NSW
Sarah-Jane Dawson Peter MacCallum Cancer Centre,VICCharley de Bock Children’s Cancer Institute, NSW
Paul Ekert Children’s Cancer Institute, NSWDavid Komander Walter and Eliza Hall Institute, VIC
Steven Lane QIMR Berghofer, QLDFabienne Mackay University of Melbourne, VIC
Marina Pajic Garvan Institute of Medical Research, NSWBelinda Parker Peter MacCallum Cancer Centre,VIC
Clare Scott Walter and Eliza Hall Institute, VICDaniel Thomas SAHMRI, University of Adelaide, SAPaul Timpson Garvan Institute of Medical Research, NSW
Anne Voss Walter and Eliza Hall Institute, VICVi Wickramasinghe Peter MacCallum Cancer Centre,VIC
Alpha Yap Institute of Molecular Bioscience, UQ, QLD
National Speakers
Registration and Abstract submission deadline extended to 30 September 2019- slots still available for selected abstract talks
@Perkins seminar Biomedical Engineering
Philip spent over a decade at UWA, between engineering and biology. He finished his PhD in the Optical+Biomedical Engineering Laboratory and latterly at BRITElab, followed by a brief post-doc. His research interests lie in observing the dynamics and mechanics of living tissues and cells with optics through a variety of computational
and numerical methods. Recently, Philip moved to the University of St Andrews in the UK, to the Optical Manipulation Group, looking broadly into computational imaging – the concomitant design of physical imaging systems and computational image recovery.
Abstract: Biophotonics, the use of optics in medicine and biology, is taking centre stage. In microscopy, especially, the capacity for super-resolution, rapid, non-destructive and relatively inexpensive imaging is behind this impetus. However, the limited imaging depth of optics and challenges in sample manipulation are prohibitive to many applications. Here, we explore how manipulating and shaping light (and sound) in both space and time can breach these limits across a breadth of imaging scales. We discuss how focussing in time and not just space in multiphoton microscopy can image deeper without correction; how acoustics can levitate living organisms and how freely accelerating Airy beams can image deeper in light-sheet microscopy; and, how multiple scattering, which is thought of as noise, can solely form and improve optical coherence tomography images. We make our advances facile, with scope for rapid, low-cost integration into commercial systems. Instead of complex hardware, we focus our efforts on computational solutions, such as deep learning and compressive sensing, offering super-resolution, fast imaging and low photodamage.
12:00noon till 1:00pm For more information, please contact Brendan Kennedy: [email protected]
SEMINAR ROOM 272, HARRY PERKINS INSTITUTE OF MEDICAL RESEARCH, NORTH CAMPUS
Philip Wijesinghe SUPA, School of Physics and Astronomy University of St Andrews, UK
"Imaging across scales with light shaping in space and time"
TUESDAY 12 NOVEMBER 2019
WESTERN AUSTRALIAN BRANCH
Announcing a meeting of the Statistical Society of Australia, W.A. Branch.
6:00 ᴘᴍ on Tuesday 12th November 2019
BIOLOGICAL SCIENCES LECTURE THEATRE (240.2.051)
BUILDING 240 MURDOCH UNIVERSITY
Using polygenic risk scores to predict risk of disease: hype, hope and statistical reality
Cathryn Lewis Professor of Genetic Epidemiology & Statistics
King’s College London ABSTRACT:
Most common disorders such as depression, breast cancer and coronary heart disease have a genetic component, which has long been observed from increased rates of disease in family members. Genetic studies have shown a polygenic component to these diseases, which is due to the cumulative effect of hundreds and thousands of genetic variants, each having a minor effect on disease risk. Individual-level polygenic risk scores can be constructed as a measure of genetic liability of disease, as a sum of the genetic loading, multiplied by the risk conferred by each variant. By the central limit theorem, polygenic risk scores have a normal distribution, and are often standardised to the population mean. However, polygenic risk scores differ by ethnicity, and principal components of genetic ancestry are necessary as covariates to control for this. Polygenic risk scores may be applied in two different settings:
(1) In research studies, to test whether disease cases have higher scores than controls, and as a tool to characterise heterogeneity within cases. Logistic regression is used as an analysis tool, with disease status (affected, unaffected) as outcome variable, polygenic risk scores as explanatory variable, and ancestry-informative principal components as covariates. Summary measures for this include the improved model fit, from change in Nagelkerke’s R2, and the AUC (Area under the curve) for predictive ability.
(2) The ultimate utility of polygenic risk scores would be to use individual polygenic risk scores, to identify those at high risk of disease, enabling them to enter relevant screening or intervention programmes.
In this seminar, I will discuss the current utility of using polygenic risk scores to predict disease risk (currently very low), and the potential for increasing their predictive ability.
ABOUT THE SPEAKER:
Cathryn Lewis is Professor of Genetic Epidemiology & Statistics at King’s College London, where she leads the Statistical Genetics Unit. Her academic training is in mathematics and statistics, and she has been involved in genetic studies since her PhD. She co-chairs the Psychiatric Genomics Consortium Major Depressive Disorder Working group, and leads the NIHR Maudsley BRC Biomarkers and Genomics theme. Her multi-disciplinary research group identifies and characterises genetic variants conferring risk of disease, including depression, schizophrenia, and stroke. A major focus is risk assessment, determining how the polygenic component of mental health disorders can be measured accurately and communicated effectively. Cathryn has a B.A. from St Hilda’s College, University of Oxford and a M.Sc. with distinction and a Ph.D. from The University of Sheffield. Cathryn Lewis is the SSA WA Branch Hansford-Miller Fellow for 2019. Members and guests are invited to mingle over wine and cheese from 5:30 ᴘᴍ onwards in the Biological Sciences Lecture Theatre. Following the meeting you are invited to dine with the speaker at Bateman Chinese Eating House & Take Away; please RSVP to Brenton Clarke [email protected] by 11 am Tuesday 12th November. Visitors are welcome. Parking is free on the Murdoch University campus after 5:00 ᴘᴍ. We suggest parking in Car Park 2 (searchable in Google Maps) that can be entered from campus entrance C on South St.
For further information please contact the Branch Secretary, Rick Tankard, Murdoch University. He can be reached by email at [email protected] or by phone at (08) 9360 2820.
PARK HERE
BSLT
Telethon Kids
Research Seminars
Wednesday 13 November 2019
12pm – 1pm
Telethon Kids Institute Seminar Room
Level 5, Perth Children’s Hospital
A light lunch will be provided at 11.45am
for those attending the seminar
Invited Guest Speaker
A/Prof Rabindra Tirouvanziam
Department of Pediatrics
Emory University School of Medicine
Center for CF and Airways Disease Research
Children’s Healthcare of Atlanta
Rabindra Tirouvanziam earned his engineering degree in Biotechnology at the Paris Institute of Technologyfor Life, Food and Environmental Sciences (Agro-Paris Tech, France) in 1994 and his PhD in DevelopmentalBiology, Lung Physiology and Immunology at the College de France and CNRS (Paris, France) in 1998. He thentrained as a Postdoctoral Fellow (1999-2004), Research Associate (2004-2008) and Instructor (2008-2011) atStanford University (CA, USA). He joined Emory University as faculty in the Department of Pediatrics andmember of the Immunology and Molecular Pathogenesis graduate program in 2011.
Research in his laboratory includes patient- and model-based studies of lung diseases such as cystic fibrosis(CF), chronic obstructive pulmonary disease (COPD), asthma, as well as other disease conditions, suchas malaria and bullous pemphigoid. The laboratory emphasizes sample analysis from patients and animalmodels using direct, high-content analyses by flow / image cytometry (for cells), proteomicsand metabolomics (for fluids) to study immunometabolic pathways and their relation to disease. Fundingsources include DARPA (PREPARE program), NIH/NHLBI, NHMRC, and the US CF Foundation.
A major contribution made by the laboratory is the discovery of a new fate of human neutrophils afterrecruitment to the airway lumen, with significant reopening of the chromatin, de novogene expression, regulatory functions toward epithelial cells, macrophages, and T-cells, and high avidity forextracellular particles (including viruses), opening critical avenues for therapeutic targeting. Following this invivo discovery, the Tirouvanziam laboratory developed an in vitro model of airway transmigration which fullyrecapitulates this new fate of human airway neutrophils and enables to mass-produce them and target them invitro.
Mechanisms of inflammatory airway disease in cystic fibrosis:
from models to patients
Streaming link : click herePassword telethonkids_seminar
CRICOS Provider Code 00301J
BIOGRAPHY Prof Paul McMenamin has been involved in teaching anatomical sciences to medical students, science students and a range of postgraduate surgical and medical specialists for around 35 years. After completing a degree in Zoology at Glasgow University, Scotland, he went on to do a PhD focussing on the anatomy of the eye and the pathology of glaucoma. In 1983 he undertook a professional training in medical anatomy (M.Sc. [Med. Sci]) also at Glasgow University (Anatomy Department) after which he migrated to Australia, where he took up a lectureship in anatomy at The University of Western Australia (1987). Paul was appointed to full Professor in 2003 and obtained his D.Sc. (Medicine) in 2010. His work focusses on the role of immune cells in a range of eye diseases including uveitis, macular degeneration and retinopathy of prematurity. He has published around 140 papers and one textbook. Paul is passionate about teaching and has been the recipient of numerous teaching accolades including the prestigious ‘Premier's Award for Excellence in Tertiary Teaching' (Western Australia) in 2007. He has pioneered new approaches to anatomy teaching such as body painting and in the last 2 years he has, along with his team at the Centre, pioneered a unique method of creating 3D prints of human anatomy, based on data obtained from laser scanning or CT scanning of dissected cadaveric specimens or from patient radiographic data. In that same year he took up the post of Director of ‘The Centre for Human Anatomy Education' in the Faculty of Medicine, Nursing and Health Sciences at Monash University, Melbourne. He continues to have an active research laboratory, funded by grants from the NH&MRC grants and other organisations. In this talk Paul will describe the current understanding of the distribution, phenotype and physiological role of ocular immune cells behind or inside the blood-retinal barriers and those in closely juxtaposed tissues outside the barrier as these factors can profoundly influence retinal homeostasis and lead to disordered immune function and vision loss. The lessons learned in parallel studies of the meninges and brain will be highlighted.
THE BAYLISS SEMINAR SERIES
Presenter: Raine Professor Mary Wlodek
Title: Critical periods and lifestyle interventions programming development disease risk
Date: Friday 14 November 2019 @ 12pm – 1pm
Venue: Bayliss Building Lecture Theatre G33
If you have suggestions for speakers, please contact our seminar coordinators Nicole Smith [email protected] and Heng Chooi [email protected] with the details and to make arrangements for an invitation.
LIGHT REFRESHMENTS WILL BE SERVED IMMEDIATELY FOLLOWING THE PRESENTATION
RPH MEDICAL RESEARCH
FORUM
Seminar Series 2019
4th Floor Seminar Room Medical Research Foundation Building Rear 50 Murray St, Perth WA 6000 Friday @ 3pm Enquiries: W/Prof Markus Schlaich Ph: 08 9224 0382 E: [email protected]
TIME: FRIDAY, 15 NOVEMBER 2019 @ 3pm VENUE: 4th Floor Seminar Room, MRF Building, Rear 50 Murray Street, Perth PRESENTER: Mr Michael Phillips TITLE: “Development and evaluation of an artificial intelligence (AI) algorithm
to detect malignant melanoma in smartphone images”
Born and grew up in old South Wales, Michael was educated at the University of London (B.Sc. Hons. I) and later the University of Nottingham Medical School (M.Med.Sci.). He became a political refugee when UK declared war on Argentina and moved to Western Australia. After too long teaching research methods and statistics to UG and PG students he became a biostatistician at WAIMR and later added RPH where he set up the MRF Biostatistics unit. With authorship of almost 600 publications and about 6,000 citations he has started to reduce his working time and increase holiday and gardening time.
Telethon Kids
Research Seminars
Wednesday 20 November 2019
12pm – 1pm
Telethon Kids Institute Seminar Room
Level 5, Perth Children’s Hospital
A light lunch will be provided at 11.45am
for those attending the seminar
Invited Guest Speaker
Dr Kirsty Short
ARC DECRA Research Fellow
School of Chemistry and Molecular Biosciences
The University of Queensland
Dr. Kirsty Short is an ARC DECRA research fellow at the School of Chemistry andMolecular Biosciences, The University of Queensland. She completed a PhD in 2013 atthe Department of Microbiology and Immunology at the University of Melbourne. In2013 she was also awarded an NHMRC CJ Martin Early Career Fellowship to go to theNetherlands to work in the Department of Virosciences at Erasmus Medical Centre.She returned to Australia at the end of 2015 to work at the University of Queensland.In 2017 she established her own independent research group studying influenza viruspathogenesis. Her group works on many different aspects of the influenza includinghow the influenza virus affects different animal species, the role of the immune systemin severe influenza virus infections and the interactions between severe influenza andchronic medical conditions such as diabetes and obesity.
Influenza in chronic disease patients: understanding the fundamentals to improve patient care
Streaming link : click herePassword telethonkids_seminar
PROFESSOR W. MURRAY THOMSON
AJ HERMAN FELLOWSHIP LECTURE
The UWA Dental School is delighted to host Professor W. Murray Thomson as the 2019 AJ Herman Fellowship Lecturer. Professor Thomson is an experienced dental researcher and specialist in dental public health. He is Editor-in-Chief of Community Dentistry and Oral Epidemiology,
and Associate Editor for the European Journal of Oral Sciences. Professor Thomson conducts research in the broad fields of dental epidemiology, dental public health and dental health services. His work over the years has had considerable impact in socio-dental epidemiology, health services research and understanding of the oral health of older people. His influential life-course work in the renowned Dunedin Study has been complemented by his pivotal role in the development and testing of a number of important self-report measures now in wide use in oral health care. His contribution to new knowledge is best evidenced by his inclusion as one of the top contributors to dental public health research in the last half century in a published bibliometric analysis (doi: 10.1111/cdoe.12249).
To date, Professor Thomson has published 351 research papers and 5 book chapters in the scientific literature; his Scopus h index is 48, and his Google Scholar h index is 70. Professor Thomson was a co-recipient of the Prime Minister’s Science Prize in 2016 and has been honoured with two IADR Distinguished Scientist Awards (the 2010 H. Trendley Dean Memorial Award and the 2014 Geriatric Oral Research Award).
Professor Thomson will be speaking on the topic: “Poor oral health casts a long shadow: findings from the Dunedin Study”
Overview of the topic: Imagine what we could find out about oral health if we followed an entire birth cohort from the cradle to the grave. The Dunedin Multidisciplinary Health and Development Study is one such study, having followed 1037 individuals born in Dunedin in 1972-3, with the most recent assessments undertaken at age 45. It has produced unprecedented and important information on the natural history of oral health and disease through the life course. In this presentation, Professor Thomson will share some findings from that study.
Please register your attendance with the event coordinator: Jane Burnell, RSVP mandatory at [email protected] by 5.00pm Tuesday 12 November 2019. Light refreshments will be served from 6.00pm with the lecture to commence at 6.30pm. This is an excellent, complimentary continuing education event brought to you by the UWA Dental School.
“Poor oral health casts a long shadow: findings from the Dunedin Study”
School of Human Sciences Seminar Series
Title: Heat Therapy: An ancient practice to target modern diseases
Presenter: Christopher T. Minson, Phd Kenneth and Kenda Singer Professor
When: Wednesday 27 November 2019 @ 1pm
Venue: John Bloomfield Lecture Theatre, UWA, School of Human Sciences (Exercise and Sport
Science) adjacent to Parkway Entrance 3. Parking on Parkway and in UWA carpark entrances 3 & 4.
https://goo.gl/maps/D1RQGxN5wGNUZfdRA
Presentation Summary: Chronic heat exposure, in the form of saunas, hot water baths, and sweat lodges have been utilized in many cultures for thousands of years. While repetitive bouts of heat exposure is generally believed to be healthy, it is only recently that we are beginning to understand the full benefits of ‘heat therapy’ across the spectrum of human health. Passive heating results in a rise in body temperature and changes in cardiovascular hemodynamics, including altered shear patterns of blood flow. There is growing evidence that these responses to acute heat stress combine over repetitive sessions to provide a stress-resistant profile to counter inflammation and oxidative
stress, as occurs with aging and chronic disease, as well as from acute damaging events such as ischemia-reperfusion injury. There is also growing evidence heat therapy can be used to target metabolic dysfunction in obesity and diabetes through improvements in insulin signaling in fat and muscle cells. This ancient therapy needs broader application to treat modern diseases, particularly in those not able to obtain the full benefits of exercise.
Speaker Biography: Dr. Christopher Minson is the Kenneth and Kenda Singer Professor of Human Physiology. His research focuses on topics related to integrative cardiovascular physiology in humans. His lab investigates how we can use exposures to extreme environments to gain a healthy and resilient physiology. He is also involved in projects related to endocrine function in women, biomarkers of aging and the risk of cardiovascular and metabolic diseases, and finding novel ways to improve thermal comfort and safely in work environments. He also works with elite athletes in the use of environmental stressors to improve performance.
Christine Page (Mon - Wed) Academic Services Officer School of Human Sciences, Faculty of Science Service • M309, 35 Stirling Hwy, Perth WA 6009 Australia T +61 8 6488 7126 • E [email protected]
CRICOS Code: 00126G
Blinded by the light: the role of miRNA in light induced retinal degenerations
Summary of the Presentation: Age-Related Macular Degeneration (AMD) is the leading cause of blindness in the western world, affecting ~200 million people globally with an expected prevalence of ~288 million by 2040. Unless treatments are found to slow the progression of these diseases, 1 in 7 of us over the age of 50 will be affected by degeneration of our central vision, leading in many cases to irreparable blindness. In this seminar Dr. Riccardo Natoli (The Australian National University, Canberra) will discuss his laboratory's work on retinal microRNA (miRNA), the master regulators of gene transcription, and how by understanding their role in retinal degenerations we might develop novel therapeutics and diagnostics for treating retinal diseases such as AMD.
Short Bio I am interested in novel strategies that reduce the severity and progression of Age-related Macular Degeneration (AMD). I aim to understand the factors that cause photoreceptors to die, and identify novel ways to protect them from degeneration. My recent work focuses on the role of microRNA (miRNA) in the degenerating retina, and examines their potential use as therapeutics. My ground-breaking work into understanding and treating this disease is funded by competitive funding agencies (such as Ophthalmic Research Institute of Australia, Retina Australia and the National Health and Medical Research Council), industry partnerships (such as EyeCo, BetaTherapeutics and Thermo Fisher Scientific), through innovation investment funding (Discovery Translational Fund) and in 2018 was awarded the prestigious ANU Translational Fellowship, all contributing to achieving my aim to address this major global health issue. I have also developed a non-invasive treatment strategy to revolutionise the management of premature infants at risk of developing Retinopathy of Prematurity (ROP) and increasing survivability, currently and ongoing collaboration with members of the ANU Medical School and Canberra Hospital. I have contributed to 50 publications, as well as presented at international and national conferences including the Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, International Society for Eye Research (ISER) the International Symposium on Retinal Degeneration (RD). I consider research-led education as an integral part of a researcher’s career. I am a lecturer in genetics and cell biology in the ANU Medical School, supervise/co-supervise 6 PhD students. I helped to establish, and convene the JCSMR HDR Mentoring Program, as well as am 2nd Year Coordinator for the ANU Medical School. In 2017, I established Clear Vision Research to support the next generation of vision researchers (www.clearvisionresearch.com).
Dr Louise Naylor is a researcher and senior lecturer at The University of Western Australia’s School of Human Sciences and an Exercise and Sports Science Australia Accredited Exercise Physiologist. She believes exercise is medicine and can be used to treat, prevent or reduce the impact of chronic disease. Her research explores how exercise training can contribute to rehabilitating and improving health outcomes in individuals with, or at risk of, cardiovascular disease. Childhood obesity and adolescents with Type 2 diabetes are another focus of her work.
After completing her undergraduate degree and PhD at UWA, Dr Naylor commenced her research career working with both elite athletes and chronically ill individuals with conditions such as heart failure and obesity. Her research investigated how exercise can improve health and wellbeing, quality of life, depression and anxiety.
In a growing and research-led field, her projects have spanned topics such as understanding how to optimise prescriptions for survivors of cancer, patients with heart failure, ageing men, and patients with diabetes.
Her research further investigates the need for exercise programs to be personalised to be effective, and the difference between different individual responses to exercise programs and why some people don’t respond at all.As an ESSA Accredited Exercise Physiologist, Dr Naylor works as a Senior Exercise Physiologist in the Cardiac Rehabilitation Service at Fiona
Stanley Hospital and is a member of UWA’s Cardiovascular Research Group.
Dr Daniel Green is a Winthrop Professor at The University of Western Australia and a Principal Research Fellow of the National Health and Medical Research Council of Australia. His 25-year career as a scientist started at Royal Perth Hospital where, with Roger Taylor and Gerry O’Driscoll, he established the first research-intensive cardiac rehabilitation service for heart failure and heart transplant patients in Australia.
After stints at the Mayo Clinic and St George’s Hospital in London, Danny returned to The University of Western Australia where he established a centre for clinical trials of exercise and lifestyle interventions in humans. He returned to the UK in the mid 2000s to accept the Chair of Cardiovascular Physiology in Liverpool, where he replicated his RPH and UWA experience by establishing clinical exercise physiology as an allied health profession in the NHS and in the higher education system.
In the late 2000s Danny, once again, returned to Perth where he now holds an NHMRC Fellowship and leads a team of 20 staff and graduate students whose
research encompasses the lifespan; from exercise training and physical activity in the prevention atherosclerosis in obese children and adolescents, to research on the best combination of exercise and medications in the management of
patients with hypercholesterolemia, diabetes, coronary disease and heart failure patients awaiting transplantation.
Event InformationWHEN: Thursday, 28 November 2019, from 1pm to 2pm
(please arrive by 12.50pm to secure your seat in advance of the talk commencing at 1pm)
WHERE: The City of Perth Library’s Auditorium, 573 Hay St, Perth WA (note: this is not the State Library)
COST: FREESIGN-UP: Via Eventbrite by visiting http://bit.ly/exerciseandyourhealth PHONE ON 08 9224 035 OR EMAIL [email protected]
Our Speakers
Exercise andYour Health
Discover things you never knew about the health effects of exercise and learn how it benefits you across your lifespan at this FREE community health event.A Q&A session will follow.
THIS FREE COMMUNITY EVENT IS PROUDLY BROUGHT TO YOU BY
RPH RESEARCH FOUNDATION IN COLLABORATION WITH THE UNIVERSITY
OF WESTERN AUSTRALIA’S SCHOOL OF HUMAN SCIENCES AND WESTERN
AUSTRALIAN CARDIOVASCULAR RESEARCH ALLIANCE (WACRA).7
First 25 registrants
for early bird deal!
Friday 6th September
Abstract submissions
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Join us in Melbourne for EAPS19 to present your research to your peers and
hear from world-class researchers! We welcome and
encourage all Honours,Masters & PhD Students to
attend and submit an abstract.
Invited speakersProf. Christine Wells, The University of Melbourne
Prof. Nadia Rosenthal, The Jackson Laboratories (USA)Dr. Damien Bates, BioCurate
Dr. Chris Langmead, Monash Institute of Pharmaceutical SciencesDr. Talitha Santini, The University of Western Australia
Dr. Irene Gallego Romero, The University of MelbourneProf. Matt Sweet, Institute of Molecular Bioscience, UQ
Prof. Ricky W. Johnstone, Peter MacCallum Cancer CentreA/Prof. Enzo Porrello, Murdoch Children’s Research Institute
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Monday 10th June
Registration Open
Friday 1st November
Registration close
Meet interstate and international
speakers and researchers from
various disciplines!
The 6th Annual EMBL Australia Postgraduate Symposium
From Models to SystemsDeciphering Biological Complexity
27-29 November 2019Victorian Comprehensive Cancer Centre, Melbourne
Telethon Kids
Research Seminars
Monday 2 December 2019
3.00pm – 4.00pm
Telethon Kids Institute Seminar Room
Level 5, Perth Children’s Hospital
Invited Guest Speaker
Assoc Professor Jasper SchipperijnResearch Unit, Active Living
University of Southern Denmark
Jasper Schipperijn is an Associate Professor with the Research Unit for Active Living atthe University of Southern Denmark. His research focuses on studying the relationbetween the built and natural environment and human behavior, and in particularevaluating the effect of changes to the environment on behavior. One of his interestlies in developing methods to objectively describe behavior and the environment thatbehavior takes place in. Much of his work builds on intervention studies or naturalexperiments that involved changes to the built environment, e.g. creating orrenovating schoolyards, urban green spaces, public open space, and bicycling facilities.Jasper has published over 85 peer-reviewed articles and numerous reports andpopular publications.Jasper has an extensive international network and he is president-elect for theInternational Society of Physical Activity and Health (ISPAH).
“Changing the Built Environment changes children’s behaviour”
Streaming link : click herePassword telethonkids_seminar
Tuesday 3 December 2019
12pm – 1pm
Conference Room; The Niche
11 Aberdare Road, Nedlands
A light lunch will be provided at 11.30am
RSVP: [email protected] 9380 3400
Telethon Kids
Research Seminars
Nicole SheersPhD Candidate, Institute for Breathing and SleepSenior Respiratory Physiotherapist, Victorian Respiratory Support Service, Austin Health
Airway clearance techniques: why, what, and when?
A clinician-researcher’s approach
Nicole is a senior physiotherapist with extensive clinicalexperience in implementing non-invasive ventilationand providing acute and long-term respiratoryphysiotherapy management for adults with chronicventilatory failure.
She has completed a randomised controlled trialinvestigating the effects of Lung Volume Recruitment(“breath-stacking”) on respiratory function, symptomsand quality of life of people living with NeuromuscularDisease, and will shortly submit her PhD on this topic.She was a member of the 228th EuropeanNeuromuscular Centre (ENMC) International Workshopon Airway Clearance Techniques in NeuromuscularDisorders which produced two “State of the Art”publications in this field, and has presented at nationaland international conferences and workshops.
Beginner workshop for microbiome-omics data analysis 3-5 Feb 2020, Perth (AUS)
Complex microbial networks have a central role in the provision and regulation ofecosystems. Multiple microbial biotechnology applications are contributing to globalefforts to achieve sustainability - through purification of wastewater, waste valorisation,bioenergy production, or to understand the role of microbiome in human disease andhealthy states.
Statistical analysis of microbiome data is challenging due to the inherent characteristicsof the data, such as high sparsity and compositional structure. Our workshop will discussthese challenges, and introduce major concepts of multivariate dimension methodsdeveloped in mixOmics. Methods in mixOmics make no distributional assumptions, arehighly flexible for unsupervised (exploratory), supervised (classification) and integrationanalyses. Various analytical frameworks will be presented ranging from dataexploration, selection of markers, integration with other omics datasets andintroduction to time-course analysis. Each methodology will be illustrated on realbiological studies. The third day is ‘BYO data’ day where you can reinforce yourlearnings on your own study! Note that the workshop is not limited to microbiome dataonly, as we will cover general omics data integration concepts. More information on ourwebsite.
Pre-requisite: a good working knowledge in R programming (e.g. handling data frame, perform simple calculations and display simple graphical outputs) to fully benefit from the course.
Instructor: Dr Kim-Anh Lê Cao
Four RHD students bursaries to cover 50% of the registration costs are generously sponsored by WAHTN. Register your interest here. EOI closes: 4 Nov 5pm AEST. Bursary recipients and registration link will be sent after this date.
Hosted by West Australian Heath Translational Network (WAHTN) and WA Human Microbiome Collaborating Centre (WAHMCC), Curtin University.
