Two Types of Sleep Non-rapid eye movement (NREM) sleep Four
different stages (1 [lightest] 4 [deepest]) Mixed-frequency EEG low
amplitude, high frequency or high amplitude, low frequency
Relatively little muscle movements Rapid eye movement (REM) sleep
Low-amplitude, high frequency EEG Synchronous eye movements
http://www.youtube.com/watch?v=AZ6I9N7t7Vc Paralysis Narcolepsy:
http://www.youtube.com/watch?v=nvMyuZKGKAYhttp://www.youtube.com/watch?v=nvMyuZKGKAY
Slide 9
Slide 10
Time Course of Sleep
Slide 11
Ontogeny of Sleep
Slide 12
Neural Control of Sleep
Slide 13
Neural Control of (NREM) Sleep Bottom-Up Processing
Slide 14
Flip-Flop Circuit Cliff Saper, Bob McCarley, Jerome Siegel
Slide 15
Neural Control of (REM) Sleep PGO waves
pons-geniculate-occipital areas OR Brainstem-Thalamus-Occipital
Cortex
Slide 16
Brain-Spinal Cord Induction of Paralysis During REM sleep
Slide 17
Slide 18
Neural Control of Spindles
Slide 19
Really Cool Probing of Sleep- Regulatory Areas With
Optogenetics
Slide 20
Circadian Rhythms
Slide 21
Basic Criteria of Circadian Rhythms Any physiological or
behavioral process that oscillates predictably across 24 hrs This
rhythm can be shifted by environmental factors (light, drugs,
mating) Persist even with the removal of environmental factors
(light, seasons)
Slide 22
Some Out-of-Phase Physiological Rhythms
Slide 23
Rhythms in Humans Nathaniel Kleitman and Eugene Aserinsky
Slide 24
Neural (SCN) Control of Rhythms SCN: Suprachiasmatic
Nucleus
Slide 25
Beyond the SCN: Molecular Control of Rhythms
Slide 26
Real-Time Recording of Molecular Feedback in the SCN
Slide 27
Working in Tandem Interaction between sleep and circadian brain
systems characterized as the two- process model
