* Based on data provided by ASEBIO members. JUNE 2017.

Spanish Red Biotech Pipeline*

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SEB

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panish Bioindustry A

ssociation, encompasses over 270 firm

s, associations, foundations, universities, technology and research centers w

hich carry out activities directly or indirectly related to biotechnology.

The wide num

ber of associates makes A

SEB

IO the m

ost appropriate meeting platform

to face up the challenges of developing the biotechnolo-gy sector in S

pain.

Around 630 com

panies research and develop products in the Spanish biotechnology sector.

Visit the online version at http://pipelines.asebio.com

/red/index.php

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w.asebio.com

DRUGS: NATIONAL COMPANIES

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RESEARCH PLATFORMS

DRUGS: NATIONAL COMPANIESCOMPANY PRODUCT TYPE THERAPEUTIC AREAS INDICATION Regulatory

Preclinical Phase I Phase II Phase III Registration Studies location

Almirall LAS41010 Biodrugs / Drugs Dermatology Atopic Dermatitis <<<<<<<<<<<<<<<<<<<<<<<<<Almirall TIldrakizumab Biodrugs / Drugs Autoimmune & Inflammation / Dermatology Psoriasis <<<<<<<<<<<<<<<<<<<<<<<<<Almirall ADP18998 Biodrugs / Drugs Dermatology Actinic Keratosis <<<<<<<<<<<<<<<<<<<<<<<<<Almirall LAS 41008 Biodrugs / Drugs Autoimmune & Inflammation / Dermatology Psoriasis <<<<<<<<<<<<<<<<<<<<<<<<<Bionanoplus Propylene Glycol Free Minoxidil Topical Formulation Biodrugs / Drugs Dermatology Hair Loss <<<<<<<<<<<<<<<<<<<<<<<<< EuropeFERRER Ozenoxacin Biodrugs / Drugs Dermatology / Infections Dermal infections <<<<<<<<<<<<<<<<<<<<<<<<<Stem Center S.L.U. GID SVF-1 Gene / Cell Therapy Others Plastic and reconstructive surgery <<<<<<<<<<<<<<<<<<<<<<<<< EuropeVENTER PHARMA LacTEST Biodrugs / Drugs Digestive System Evaluation of hypolactasia <<<<<<<<<<<<<<<<<<<<<<<<<Almirall P3070 Biodrugs / Drugs Autoimmune & Inflammation / Dermatology Nail Psoriasis <<<<<<<<<<<<<<<<<<<<Almirall P3058 Biodrugs / Drugs Dermatology Onychomycosis <<<<<<<<<<<<<<<<<<<<NATAC Retriacyl Biodrugs / Drugs Ophthalmology and optometry Retinitis Pigmentosa <<<<<<<<<<<<<<<<<<<< EuropePharmaMar Lurbinectedin Biodrugs / Drugs Cancer Platinum-Resistant Ovarian Cancer <<<<<<<<<<<<<<<<<<<<PharmaMar Aplidin Biodrugs / Drugs Cancer Multiple Myeloma <<<<<<<<<<<<<<<<<<<<PharmaMar Lurbinectedin Biodrugs / Drugs Cancer Small Cell Lung Cancer <<<<<<<<<<<<<<<<<<<<PRAXIS BERENICE Biodrugs / Drugs Genetic Diseases and Dysmorphic syndromes Chagas <<<<<<<<<<<<<<<<<<<<PRAXIS EPIPROT Biodrugs / Drugs Dermatology Diabetic Foot <<<<<<<<<<<<<<<<<<<<REIG JOFRE/LABORATORIOS MEDEA Topical solution Biodrugs / Drugs Dermatology Skyn infection <<<<<<<<<<<<<<<<<<<<SOM Biotech SOM0226 Biodrugs / Drugs Central Nervous System / Genetic Diseases and Dysmorphic syndromes / Metabolic / Endocrinology All Types of Transthyretin Amyloidosis: Familial Amyloid Polyneuropathy, Familial Amyloid Cardiomyopathy, Senile Systemic Amyloidosis,

Ophthalmic and CNS forms <<<<<<<<<<<<<<<<<<<<Sylentis SYL1001 Biodrugs / Drugs Ophthalmology and optometry Dry Eye Syndrome <<<<<<<<<<<<<<<<<<<<Thrombotargets TT-173 Biodrugs / Drugs Blood and Lymphatic systems Haemorrhage <<<<<<<<<<<<<<<<<<<<Ability Pharmaceuticals ABTL0812 Biodrugs / Drugs Cancer Lung, Endometrial and Pancreatic Cancer <<<<<<<<<<<<<<<Araclon Biotech ABvac40 Biodrugs / Drugs Central Nervous System Alzheimer’s Disease <<<<<<<<<<<<<<<Archivel Farma RUTI® Vaccines Infections Active tuberculosis - Latent Tuberculosis <<<<<<<<<<<<<<< Europe and

South AfricaESTEVE E-52862 Biodrugs / Drugs Analgesia & Pain Neuropathic Pain <<<<<<<<<<<<<<<ESTEVE E-58425 Biodrugs / Drugs Analgesia & Pain Acute and chronic, moderate to severe pain <<<<<<<<<<<<<<<FERRER Lorediplon Biodrugs / Drugs Central Nervous System Sleep disorders <<<<<<<<<<<<<<<FUND. PROGRESO Y SALUD / IATA (SAS) Engineered Corneas Gene / Cell Therapy Ophthalmology and optometry Corneal ulcers <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / IATA (SAS) Autologous Bone Marrow progenitors, Adipose and Bone Marrow Mesenchymal stem cells Gene / Cell Therapy Autoimmune & Inflammation / Central Nervous System Stroke, Multiple Sclerosis and ALS <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / IATA (SAS) Autologous Bone Marrow Mononuclear cells and Adipose Mesenchymal stem cells Gene / Cell Therapy Digestive System Extended Liver resection, Faecal Incontinence <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / IATA (SAS) Autologous Bone Marrow Mononuclear cells Gene / Cell Therapy Cardiovascular and circulatory systems / Metabolic / Endocrinology Acute Myocardial Infarction/Dilated Myocardiopathy/Chronic Ischemic Cardiopathy/Critical Limb Ischemia in diabetic & non patients <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / IATA (SAS) Allogeneic Adipose Mesenchymal stem cells / Allodepleted Bone Marrow Progenitors Biodrugs / Drugs Autoimmune & Inflammation / Blood and Lymphatic systems Chronic Graft versus Host Disease, Haematological Malignancies <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-14003 Biodrugs / Drugs Dermatology / Infections Treatment of mucocutaneous herpes infections <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-91 Melatonine Solution Biodrugs / Drugs Infections Sepsis <<<<<<<<<<<<<<<GP-PHARM Octeotride LAR Biodrugs / Drugs Metabolic / Endocrinology Acromegaly <<<<<<<<<<<<<<< WorldwideHistocell HC016 Biodrugs / Drugs Central Nervous System Acute Spinal Cord Injury <<<<<<<<<<<<<<<Histocell HR004 Biodrugs / Drugs Musculoskeletal Disorders Bone Regeneration <<<<<<<<<<<<<<<Lipopharma Therapeutics LP561A1 Biodrugs / Drugs Cancer Glioma and other solid tumours <<<<<<<<<<<<<<<PharmaMar PM184 Biodrugs / Drugs Cancer Advanced Breast cancer <<<<<<<<<<<<<<<PharmaMar Lurbinectedin Biodrugs / Drugs Cancer BRCA Associated Breast Cancer <<<<<<<<<<<<<<<PharmaMar Aplidin Biodrugs / Drugs Cancer Multiple Myeloma in combination with bortezomid <<<<<<<<<<<<<<<PharmaMar Aplidin Biodrugs / Drugs Blood and Lymphatic systems / Cancer T Cell Lymphoma <<<<<<<<<<<<<<<PharmaMar Lurbinectedin Biodrugs / Drugs Cancer Basket trial <<<<<<<<<<<<<<<PRAXIS LP561A1 Biodrugs / Drugs Cancer Glioma <<<<<<<<<<<<<<<PRAXIS BIOTCARM Biodrugs / Drugs Cancer Glioma <<<<<<<<<<<<<<<Sanifit SNF472 Biodrugs / Drugs Cardiovascular and circulatory systems / Metabolic / Endocrinology Cardiovascular disease (dialysis) <<<<<<<<<<<<<<<Sanifit SNF472 Biodrugs / Drugs Cardiovascular and circulatory systems / Metabolic / Endocrinology Calciphylaxis (dialysis) <<<<<<<<<<<<<<<SOM Biotech SOM3355 Biodrugs / Drugs Central Nervous System / Genetic Diseases and Dysmorphic syndromes Huntington’s disease, Tourette syndrome and Tardive Dyskinesia <<<<<<<<<<<<<<<SOM Biotech SOM1201 Biodrugs / Drugs Central Nervous System / Genetic Diseases and Dysmorphic syndromes Adrenoleukodystrophy <<<<<<<<<<<<<<<SPHERIUM BIOMED S.L SP12006 Biodrugs / Drugs Analgesia & Pain / Musculoskeletal Disorders Treatment of mild to moderate muscular pain (related to sportive practice DOMS and Temporomandibular Joint Disorder) <<<<<<<<<<<<<<<SPHERIUM BIOMED S.L SP14019 Biodrugs / Drugs Dermatology Topical spray of cyclosporine to treat Atopic Dermatitis & Psoriasis <<<<<<<<<<<<<<<SPHERIUM BIOMED S.L SP13004 Biodrugs / Drugs Cancer / Dermatology / Digestive System Prevention and treatment of radiochemotherapy-induced mucositis in head and neck cancer <<<<<<<<<<<<<<<Sylentis Bamosiran/SYL040012 Biodrugs / Drugs Ophthalmology and optometry Ocular Hypertension, Glaucoma <<<<<<<<<<<<<<<Bionure BN201 Biodrugs / Drugs Central Nervous System / Ophthalmology and optometry Acute Optic Neuritis, Neuromyelitis Optica, Multiple Sclerosis <<<<<<<<<<FERRER FAB-117 Gene / Cell Therapy Central Nervous System Spinal Cord Injury <<<<<<<<<<FUND. PROGRESO Y SALUD / IATA (SAS) Autologous Bone Marrow Mononuclear cells Gene / Cell Therapy Cardiovascular and circulatory systems / Metabolic / Endocrinology Critical Limb Ischemia in diabetic patients <<<<<<<<<< WorldwideFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13014 Combination of Ketamine and Meperidine Biodrugs / Drugs Autoimmune & Inflammation  Mucositis <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-116 Biodrugs / Drugs Analgesia & Pain Fibromyalgia <<<<<<<<<<Genmedica Therapeutics GMC-252 Biodrugs / Drugs Metabolic / Endocrinology Type 2 Diabetes <<<<<<<<<< EuropeGP-PHARM Pegylated Liposomes for Oncology Biodrugs / Drugs Cancer Advanced Ovarian Cancer, Advanced Breast Cancer <<<<<<<<<< WorldwideGP-PHARM TERIPERATIDE Biodrugs / Drugs Musculoskeletal Disorders Osteoporosis <<<<<<<<<<GP-PHARM depot form Biodrugs / Drugs Cancer Several <<<<<<<<<<GP-PHARM Triptorelina Depot 1-3 Biodrugs / Drugs Cancer Prostate Cancer <<<<<<<<<< Europe and LatinamericaGP-PHARM Octeotride MAR Biodrugs / Drugs Cancer / Digestive System Acute diarrhoea post chemotherapy <<<<<<<<<< WorldwideGP-PHARM Lutrate Depot 45 mg Biodrugs / Drugs Cancer Prostate Cancer <<<<<<<<<< WorldwideMinoryx MIN-102 Biodrugs / Drugs Central Nervous System / Metabolic / Endocrinology X-linked Adrenoleukodystrophy <<<<<<<<<<Oryzon ORY-2001 Biodrugs / Drugs Central Nervous System Alzheimer’s disease, Multiple Sclerosis, Huntington’s disease, other dementias, <<<<<<<<<<Oryzon ORY-1001 Biodrugs / Drugs Blood and Lymphatic systems / Cancer Acute Myeloid Leukaemia, Solid tumors, Other oncohaematology indications <<<<<<<<<<PaloBiofarma PBF-509 Biodrugs / Drugs Cancer / Central Nervous System Attention-Deficit, Hyperactivity Disorder (ADHD), Lung Cancer <<<<<<<<<<PaloBiofarma PBF680 Biodrugs / Drugs Respiratory and Pulmonary system Asthma <<<<<<<<<<PharmaMar Lurbinectedin Biodrugs / Drugs Cancer Combination trials <<<<<<<<<<PharmaMar PM184 Biodrugs / Drugs Cancer Combination trials <<<<<<<<<<VCN Biosciences VCN-01 Gene / Cell Therapy Cancer Pancreatic cancer <<<<<<<<<< EuropeAbility Pharmaceuticals ABTL1014 Biodrugs / Drugs Blood and Lymphatic systems / Cancer Leukaemia and Lymphomas <<<<<Bioibérica BIS014 Biodrugs / Drugs Analgesia & Pain / Central Nervous System Neuropathic pain <<<<< EuropeBionanoplus Psorio-Plus spray and gel Biodrugs / Drugs Dermatology Help improving and soothing the manifestations of hyperkeratinized skins <<<<<Bioncotech Therapeutics BO-110 Biodrugs / Drugs Cancer Solid tumors <<<<< EuropeDIOMUNE SL IV1303 Biodrugs / Drugs Autoimmune & Inflammation / Cardiovascular and circulatory systems / Genetic Diseases and

Dysmorphic syndromes / Infections Sepsis treatment, Stroke, Rare diseases (CDH), Leishmania, ZIKV <<<<<ENTRECHEM EC-70124 po for prostate cancer Biodrugs / Drugs Cancer Castration resistant prostate cancer <<<<<ENTRECHEM EC-8042 iv for liposarcoma Biodrugs / Drugs Cancer Liposarcoma myxoide <<<<<ENTRECHEM EC-70124 po for AML Biodrugs / Drugs Cancer Acute myeloid leukemia <<<<<ENTRECHEM EC-8042 iv for Ewing sarcoma Biodrugs / Drugs Cancer Solid tumours <<<<<ENTRECHEM EC-8042 iv for Triple negative breast cancer Biodrugs / Drugs Cancer Triple negative breast cancer <<<<<ENTRECHEM EC-70124 po for TNBC Biodrugs / Drugs Cancer Triple negative breast cancer <<<<<ESTEVE EGT-101 Gene / Cell Therapy Genetic Diseases and Dysmorphic syndromes Sanfilippo A syndrome:Lysosomal storage rare disease <<<<<ESTEVE MUMO1 Biodrugs / Drugs Analgesia & Pain Acute and chronic, moderate to severe pain <<<<<FECYT Pylori Biodrugs / Drugs Infections H. pylori <<<<<FECYT p300 Biodrugs / Drugs Cancer Cancer <<<<<FECYT p38 Biodrugs / Drugs Analgesia & Pain / Central Nervous System Neuropathic Pain <<<<<FERRER FAB-120 Biodrugs / Drugs Ophthalmology and optometry Diabetic Retinopathy <<<<<FERRER FAB-112 Gene / Cell Therapy Ophthalmology and optometry Corneal Diseases <<<<<FIBROSTATIN FSSME12 Biodrugs / Drugs Cancer Lung and Breast Cancer <<<<< EuropeFUND. PROGRESO Y SALUD / IATA (SAS) FIBAO-13007 Gene / Cell Therapy Cancer Cancer cells <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-13002 Biodrugs / Drugs Cancer Multiple myeloma <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-121 Gene / Cell Therapy Autoimmune & Inflammation Transplant <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-99 Biodrugs / Drugs Metabolic / Endocrinology Nanoemulsions for the treatment of obesity <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-77 Biodrugs / Drugs Central Nervous System Hydroxytyrosol ethers <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-13007 Biodrugs / Drugs Cardiovascular and circulatory systems / Metabolic / Endocrinology Treatment and/or Prevention of cardiovascular and metabolic diseases <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-13001 Biodrugs / Drugs Metabolic / Endocrinology Treatment and/or Prevention of Non-alcoholic fatty liver disease (NAFLD) <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-13007 Gene / Cell Therapy Cancer Hepatocarcinoma <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FRM-5 Gene / Cell Therapy Others Transplant <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-13007 Biodrugs / Drugs Cardiovascular and circulatory systems / Metabolic / Endocrinology Treatment and/or prevention of metabolic and cardiovascular diseases <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-13020 Biodrugs / Drugs Central Nervous System Alzheimer’s disease <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-14012 Biodrugs / Drugs Infections Multirresistant infections <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI 141 Biodrugs / Drugs Infections Sepsis, Acute lung injury <<<<< EuropeFUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) Mutli-target siRNA approach Gene / Cell Therapy Autoimmune & Inflammation / Kidney and Genitourinary system Chronic Kidney Disease (CKD)/ Akute Kidney Injury (AKI) <<<<<FUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) New generation of peptides Biodrugs / Drugs Autoimmune & Inflammation / Blood and Lymphatic systems / Cardiovascular and circulatory systems /

Kidney and Genitourinary system / Metabolic / Endocrinology / Ophthalmology and optometry Chronic complications of Diabetes <<<<<GP-PHARM Risperidona Depot Biodrugs / Drugs Central Nervous System Schizophrenia <<<<< WorldwideHistocell HR016 Biodrugs / Drugs Respiratory and Pulmonary system Acute Lung Injury <<<<<Lipopharma Therapeutics LP226A1 Biodrugs / Drugs Central Nervous System Alzheimer’s Disease <<<<< EuropeNeuron Bio NST0037 Biodrugs / Drugs Central Nervous System Mild Cognitive Impairment / Epilepsy <<<<< EuropenLife Therapeutics, S.L. NLF-PD-1233 Biodrugs / Drugs Central Nervous System Parkinson Disease <<<<< Europe and USAOryzon ORY-3001 Biodrugs / Drugs Others Non-oncological disease <<<<<PaloBiofarma PBF-695 Biodrugs / Drugs Ophthalmology and optometry Glaucoma <<<<<PaloBiofarma PBF-999 Biodrugs / Drugs Central Nervous System Huntington Disease <<<<<Pevesa PEV pept. 01-02 Biodrugs / Drugs Metabolic / Endocrinology Metabolic Syndrome <<<<< EuropePRAXIS OLEA Biodrugs / Drugs Dermatology Antiaging drugs and nutraceutics <<<<<PRAXIS ANTIAGE Biodrugs / Drugs Dermatology Antiaging drugs and nutraceutics <<<<<SPHERIUM BIOMED S.L SP15016 Biodrugs / Drugs Cardiovascular and circulatory systems / Kidney and Genitourinary system Prevention of Acute Kidney Injury in Angioplasty patients receiving high dose contrast agent <<<<<Sylentis siRNA Biodrugs / Drugs Autoimmune & Inflammation / Digestive System Crohn’s disease and ulcerative colitis <<<<<Sylentis siRNA Biodrugs / Drugs Ophthalmology and optometry Ocular Allergy <<<<<TERACLON IDF V-32-R Biodrugs / Drugs Ophthalmology and optometry Glaucoma <<<<<TERACLON IDF V32R Biodrugs / Drugs Ophthalmology and optometry Diabetic Retinopathy <<<<<VIVEBIOTECH GMP-grade viral vectors Gene / Cell Therapy Genetic Diseases and Dysmorphic syndromes Development of gene therapy products in strict compliance with requirements established under current legislation and in accordance with best

practice guidelines in a cleanroom for the production of medicines for Stage I/II clinical trials <<<<<Vivia Biotech Vivia 009 Biodrugs / Drugs Blood and Lymphatic systems / Central Nervous System Non Hodgkin Lymphoma, CNS <<<<< Europe

COMPANY TYPE DESCRIPTION R+D Preliminary Validation

Clinical Validation Register Ready To

Market3P BIOPHARMACEUTICALS CRO / CMO Scale up and No GMP production for Preclinical studies <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Analytics development and validation platform (API, IMP, IPC) for Biosimilars <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Analytics development and validation platform (API, IMP, IPC) for New biological entities <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Bioprocess Development/Optimization Platform (USP/DSP) <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Freedom-to-operate platform in Bacteria, yeast and mammalian <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Production of advanced Therapy Medicinal Products <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO API/ IMP process development and GMP manufacturing <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Biologics production: New Biological Entities (mAbs, vaccines, fusion proteins) and Biosimilars/Biobetters from microbial fermentation and mammalian cell culture <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Development of API formulation <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO Stability Studies (API/ IMP/Cell banks) <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO GMP Cell Bank Manufacturing (MCB/WCB/EPCB) and storage <<<<<<<<<<<<<<<<<<<<<<<<<3P BIOPHARMACEUTICALS CRO / CMO GMP production (fermenters up to 1000L and Bioreactors up to 400L) for Clinical trials and Commercial stage <<<<<<<<<<<<<<<<<<<<<<<<<AC-Gen Reading Life Screening Phatogenomics <<<<<<<<<<<<<<<<<<<<<<<<<AC-Gen Reading Life Screening NGS, Sequence Capture; Genetic Diseases and Dysmorphic syndromes; Exome Analysis, Genomics, infections <<<<<<<<<<<<<<<<<<<<<<<<<APTUS Biotech Drug Delivery / Enabling Technologies Aptamer selection and characterization <<<<<<<<<<<<<<<<<<<<<<<<<Bionaturis CRO / CMO / Screening Biobide’s platfom for Toxicity and Efficacy Assays of active compounds in Zebra Fish (validated and included in international regulations). Long track record of services to pharmas, agro-food, and cosmetic companies <<<<<<<<<<<<<<<<<<<<<<<<<BIOPOLIS CRO / CMO Contract manufacturing: upstream and downstream development, analytical development, scale-up <<<<<<<<<<<<<<<<<<<<<<<<<BIOPOLIS CRO / CMO Metagenomics and metabolomic analysis <<<<<<<<<<<<<<<<<<<<<<<<<BIOPOLIS CRO / CMO / Screening Preclinical validation platforms: C.elegans model for functional food, ingredients and drug trials <<<<<<<<<<<<<<<<<<<<<<<<<Bioraw CRO / CMO Industrial fermentation and downstream <<<<<<<<<<<<<<<<<<<<<<<<<CIBER/CIBER-BBN CRO / CMO / Enabling Technologies / Others Production of Customized Biomaterials, Nanomaterials & Nanoconjugates <<<<<<<<<<<<<<<<<<<<<<<<<CIBER/CIBER-BBN CRO / CMO / Enabling Technologies / Others Production of Customized Biomolecules (Antibodies, Proteins and Peptides) <<<<<<<<<<<<<<<<<<<<<<<<<FUND. PROGRESO Y SALUD (BIONAND) CRO / CMO / Screening Genomics and Bioinformatic Platform of Andalusia / Nanoimaging & Metabolomic platform / Biobank <<<<<<<<<<<<<<<<<<<<<<<<<Health in Code Screening Next Generation Sequencing by HiSeq 1500 <<<<<<<<<<<<<<<<<<<<<<<<<Histocell CRO / CMO Cell shipping medium. To develop ready-to-use cell based models for research <<<<<<<<<<<<<<<<<<<<<<<<<Ingeniatrics Drug Delivery Process and technologies for customized Drug Delivery Formulations <<<<<<<<<<<<<<<<<<<<<<<<<Iproteos Enabling Technologies / Screening IPRO Technology is a platform for the discovery and development of peptidomimetics able to disrupt and/or modulate protein-protein or protein-ligand interactions <<<<<<<<<<<<<<<<<<<<<<<<<Leitat CRO / CMO / Drug Delivery / Enabling Technologies / Screening Polyclonal & Monoclonal Antibody Generation and Production Platform. Recombinant proteins, Immunization, Serum title, Mouse polyclonals, Fusion, Screening, Cloning, Hybridomas, Isotyping, Production & Purification, F(ab’)2, Fab, scFv, Conjugation, ELIS <<<<<<<<<<<<<<<<<<<<<<<<<Leitat CRO / CMO / Enabling Technologies / Screening Antibody & Protein Engineering Platform: Cloning, Chimeric mAbs, Humanized mAbs, scFv fragments, Fusion proteins Modeling, Transient expression, Stable clones, Nanobodies, Bispecifics, ADCs, Production, Biosimilars <<<<<<<<<<<<<<<<<<<<<<<<<Leitat CRO / CMO / Enabling Technologies / Screening In vivo animal model platform (Oncology, Angiogenesis, Efficacy, pre-Tox, Biodistribution, pre-Pk, Drug Reprofiling) Syngenic & xenogenic, Subcutaneous & orthotopic, Experimental & spontaneous metastasis, Patient Derived Orthotopic Xenografts (PDX, avata…) <<<<<<<<<<<<<<<<<<<<<<<<<Plebiotic Screening Molecular Dynamics product v2 (PleMD v2.0) <<<<<<<<<<<<<<<<<<<<<<<<<SISTEMAS GENÓMICOS Screening Whole exome resequencing in humans permits the identification of the new genes associated with both rare and common diseases <<<<<<<<<<<<<<<<<<<<<<<<<SISTEMAS GENÓMICOS Screening Pharmacogenomics. Markers of drug response <<<<<<<<<<<<<<<<<<<<<<<<< Therapeutics Screening Drug screening / Discovery / validation on cancer stem cells, phenotypic HTS screening, secondary validation to in vivo efficacy testing <<<<<<<<<<<<<<<<<<<<<<<<<Vivia Biotech CRO / CMO / Enabling Technologies / Screening Cytometry Analysis for Personalized Medicine/Diagnosis/Pharma Profiling. Drug profiling and biomarker discovery collaborations <<<<<<<<<<<<<<<<<<<<<<<<<ZeClinics CRO / CMO / Screening Discovery-preclinical safety services for drug discovery using zebrafish. ZeTox: acute, chronic, general and organ-specific toxicology tests <<<<<<<<<<<<<<<<<<<<<<<<<ZeClinics CRO / CMO / Enabling Technologies / Screening Discovery-preclinical disease modeling services using zebrafish. ZeGenesis: generation of knock-out, knock-in, transgenics zebrafish or cell lines through CRISPR/Cas9 <<<<<<<<<<<<<<<<<<<<<<<<<ZeClinics CRO / CMO / Enabling Technologies / Screening Discovery-preclinical services for drug efficacy using zebrafish. ZeEfficacy: early bioactivity evaluation of compound libraries with high-content phenotypical screenings <<<<<<<<<<<<<<<<<<<<<<<<<Bionanoplus Drug Delivery NANO-GES: drug delivery using polymeric encapsulation with esters of poly (methyl vinyl ether-co-maleic anhydride) PCT/EP2012/056900 <<<<<<<<<<<<<<<<<<<<Bionaturis CRO / CMO Development/manufacturing of active principles in a universally scalable technology in eukaryotes (FLYLIFE) <<<<<<<<<<<<<<<<<<<<ASCIL Biopharm Drug Delivery / Enabling Technologies ASRET Platform: Biomedical devices for implantable systems administration <<<<<<<<<<<<<<<ASCIL Biopharm Drug Delivery / Enabling Technologies ASMEX Platform: Safety syringes alternatives-prefilled ready to use medical devices for parenteral administration/syringes or cartridge <<<<<<<<<<<<<<<Bionanoplus Drug Delivery SANP: drug delivery using polimeric encapsulation with a vegetable hydrophobic protein PCT/EP2013/052795 <<<<<<<<<<<<<<<Bionanoplus Drug Delivery MUCO-LAST Technology: Compositions for mucosal adhesion and uses thereof. Intelectual property rights until 2036 (PATENT: EP16382136) <<<<<<<<<<<<<<<Bionaturis Drug Delivery Zip’s Zera platform for normalization of the immune response raised by recombinant vaccines, DNA/RNA vaccines. Elimination of cold-chain for storage by formation of metastable nanostructures comprising the antigen before delivery <<<<<<<<<<<<<<<FUND. PROGRESO Y SALUD (IATA) CRO / CMO Maturing technological platform in advanced therapies: setting up and monitoring of clinical trials <<<<<<<<<<<<<<<Fundacion MEDINA CRO / CMO Chemical Isolation & Structural Elucidation <<<<<<<<<<<<<<<Fundacion MEDINA CRO / CMO Microbial and Mammalian cell culturing <<<<<<<<<<<<<<<Fundacion MEDINA Screening Microbial Natural Product Libraries <<<<<<<<<<<<<<<Fundacion MEDINA CRO / CMO Preclinical Safety Platform <<<<<<<<<<<<<<<Fundacion MEDINA CRO / CMO Bioanalytical Platform <<<<<<<<<<<<<<<Fundacion MEDINA Screening High throughput screening platform for drug discovery <<<<<<<<<<<<<<<IRYCIS Others / Screening miRNA platform to collaborate in the development and commercialization of new biomarkers for diagnosis, prognosis and drug response <<<<<<<<<<<<<<<Leitat CRO / CMO / Drug Delivery / Enabling Technologies / Screening Oncology & Angiogenesis: Target discovery, Drug Efficacy, Drug development <<<<<<<<<<<<<<<Leitat CRO / CMO / Enabling Technologies / Screening Skin health & Cosmetics: Safety Beauty Dermatology <<<<<<<<<<<<<<<Leitat CRO / CMO / Drug Delivery / Enabling Technologies / Screening Diagnosis & Biosensors: Biomarkers, Theragnostics, Remote sensing <<<<<<<<<<<<<<<Leitat CRO / CMO / Drug Delivery / Enabling Technologies Metabolomics & Bioanalytics: Mass spectrometry, Chromatography, Bioinformatics <<<<<<<<<<<<<<<Leitat CRO / CMO / Drug Delivery / Enabling Technologies / Screening Regenerative medicine: Pharmacology, In vivo imaging, Stem cell therapy, Sports medicine, Muscle and tendon in vivo models <<<<<<<<<<<<<<<Leitat CRO / CMO / Drug Delivery / Enabling Technologies / Screening Nutrition & Food Sciences: Body barriers (skin, digestive,,,), ADMEtox, Energetic metabolism, Microbiota <<<<<<<<<<<<<<<Lipopharma Therapeutics Enabling Technologies A novel therapeutic approach: Membrane Lipid Therapy (MLT) <<<<<<<<<<<<<<<OPERON Screening Opegen S.pneumoniae: Molecular test for the genotyping of Streptococcus pneumoniae infections <<<<<<<<<<<<<<<ASCIL Biopharm Enabling Technologies ASTECH Platform: Optimized presentation and technologies for freeze-dried drug product and formulation-prefilled system. Improvement of FD for injectables products <<<<<<<<<<ASCIL Biopharm Drug Delivery / Enabling Technologies ASTIC Platform: Implantable biodegradable systems and medical devices for administration. From daily to semi-annual delivery of biologics or pharma drugs. Micro/nanoimplantable solid system <<<<<<<<<<ASCIL Biopharm Drug Delivery ASMAT Platform: New semisolid Biodegradable biomaterials for controlled release applications <<<<<<<<<<Bionanoplus Drug Delivery Polymeric nanoemulsion technology for topical application <<<<<<<<<<Bionanoplus Drug Delivery Antigen delivery for vaccines. Encapsulation of antigens with a polymer to increases the vaccination efficacy <<<<<<<<<<Bionos Biotech SL CRO / CMO / Screening In vitro Cellular Models (HaCaT, NHDF, NHEK, NHEM, HFDPC, RHE, Eleutheroembryos, etc.). Efficacy and Toxicity Tests. Antioxidant and Detoxification (Lipid Peroxidation, Glycation, Carbonylation..), UV/IR/HEV Protection, DNA Repair, Cell Proliferation <<<<<<<<<<CIBER/CIBER-BBN CRO / CMO / Enabling Technologies / Screening Preclinical Validation-Bioimaging. Integrated Infrastructure on Production and characterization of Nanomaterials, Biomaterials and systems in Biomedicine <<<<<<<<<<CIBER/CIBER-BBN CRO / CMO / Enabling Technologies Preclinical Validation-Tissue, Biomaterial and Surface Characterization <<<<<<<<<<ENTRECHEM Others Synthetic Biology for Human Health. Opening up the chemical space of complex bacterial natural products for oncology and immunosuppression applications <<<<<<<<<<FUND. PROGRESO Y SALUD (OTT-SSPA-FISEVI/ IBIS)(SAS) Screening Cell lines & Animal Models <<<<<<<<<<Fundacion MEDINA Screening High throughput screening platform for drug discovery <<<<<<<<<<IMMUNOSTEP Enabling Technologies Reagents, columns and devices for Cell separation in Blood and Lymphatic systems <<<<<<<<<<Ingeniatrics Drug Delivery Pneumo: New European research project aims to tackle antibiotic resistance issue raised by WHO via inhalable nanotherapeutics <<<<<<<<<<Ingeniatrics Screening Platform for highthroughput analysis of microorganisms. Accelerated diagnosis of bacterial diseases. Several <<<<<<<<<<Ingeniatrics Drug Delivery Platform for coating of Medical Devices. Odontology <<<<<<<<<<Minoryx Enabling Technologies SEE-Tx: Site-directed Enzyme Enhancement Therapy <<<<<<<<<<Neuron Bio Screening Drug discovery and development activities focused on neurodegenerative diseases, inflammatory processes and hypercholesterolemic conditions (HTS preclinical platform) <<<<<<<<<<Plebiotic Enabling Technologies Novel software for molecular design of antibodies, based on molecular dynamics <<<<<<<<<<AC-Gen Reading Life Screening Phatogenomis <<<<<ASCIL Biopharm Drug Delivery ASLINX Platform: Parenteral controlled release liquid technology based on Inherent characteristics of the API <<<<<ASCIL Biopharm Drug Delivery ASEM Platform: Parenteral controlled release technology built specifically around inherent characteristics of the API to get an optimal PK/PD with or without excipients <<<<<BIOPOLIS CRO / CMO / Screening Novel functional probiotics screening, validation and production <<<<<BIOPOLIS CRO / CMO Recombinant protein expression systems <<<<<CIBER/CIBER-BBN Enabling Technologies / Others High Performance Computing. Integrated Infrastructure on Production and characterization of Nanomaterials, Biomaterials and systems in Biomedicine <<<<<Enzymlogic CRO / CMO / Screening Development of an assay platform to perform binding kinetic profiling of KINASE inhibitors in a HTS format <<<<<Enzymlogic CRO / CMO / Screening Development of an assay platform to perform binding kinetic profiling of GPCR agonist and antagonist in a HTS format <<<<<FUND. PROGRESO Y SALUD (BIONAND) Drug Delivery Liposome delivery System (Prostate Cancer) <<<<<FUND. PROGRESO Y SALUD (CABIMER) CRO / CMO / Screening Cancer Screening Cell lines & Animal Models <<<<<FUND. PROGRESO Y SALUD (CABIMER) Enabling Technologies Hybridome/Antibody Production Platform <<<<<Fundacion MEDINA Enabling Technologies / Screening Mass spectrometry metabolomics <<<<<IMEGEN Screening Whole exome sequencing <<<<<Ingeniatrics Drug Delivery Method for producing elongatedd structures such as fibers from polymer solutions by straining flow spinning <<<<<InKemia IUCT group CRO / CMO Drug development platform: GMP Manufacturing of investigational drugs; Production of solid, semisolid and liquid (non-sterile) pharmaceutical products, Production of medicinal products under research and veterinary medicinal products <<<<<InKemia IUCT group CRO / CMO Drug development platform: Stability studies under ICH conditions (Product storage according to ICH regulations, Product testing, Development of study protocol, Preparation for the study report) <<<<<InKemia IUCT group CRO / CMO Drug development platform: Galenic development (Pre-formulation studies , Formulations development, Formulations Optimization, Stability Formulations, Comparison of dissolution profiles, Batch Productions at pilot levels, Support in technological transfer <<<<<Integromics Screening Genomics Analysis for Personalized Medicine/Diagnosis <<<<<Intelligent Pharma CRO / CMO / Enabling Technologies Software development. Tailor-made solutions applied to the life sciences sector <<<<<Intelligent Pharma CRO / CMO / Enabling Technologies / Screening Computational chemistry applied to in silico drug discovery (hit identification, drug reprofiling, mechanism of action, lead optimization). High Performance Computing <<<<<Plebiotic Enabling Technologies Novel reverse docking software, for repositioning purposes <<<<<VIVEBIOTECH CRO / CMO Production of viral vectors deriving from lentivirus, adenovirus, and adeno-associated virus (UNE-EN ISO 9001:2008) providing services to academic researchers and industry for in vitro and in vivo research studies <<<<<Vytrus Biotech CRO / CMO Development and manufacturing of recombinant proteins through the technology of plant cell cultures <<<<<

* Based on data provided by ASEBIO members. JUNE 2017.

Spanish Red Biotech Pipeline*

w w w . a s e b i o . c o m

Sp

an

ish

Red

Bio

tech

Pip

elin

e 2

01

7

Sp

an

ish B

ioin

du

stry Asso

ciatio

n A

SEB

IO, the S

panish Bioindustry A

ssociation, encompasses over 270 firm

s, associations, foundations, universities, technology and research centers w

hich carry out activities directly or indirectly related to biotechnology.

The wide num

ber of associates makes A

SEB

IO the m

ost appropriate meeting platform

to face up the challenges of developing the biotechnolo-gy sector in S

pain.

Around 630 com

panies research and develop products in the Spanish biotechnology sector.

Visit the online version at http://pipelines.asebio.com

/red/index.php

ww

w.asebio.com

OTHER TECHNOLOGIES

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DIAGNOSTICS AND PERSONALIZED MEDICINE

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DIAGNOSTICS AND PERSONALISED MEDICINE

COMPANY PRODUCT TYPE THERAPEUTIC AREA INDICATION R+D Preclinical Validation

Clinical Validation Register Ready to

market Studies location

BTI Biotechnology Institute PRGF-Endoret Technology Biomaterials & Tissue Therapy Dental / Dermatology / Musculoskeletal Disorders / Ophthalmology and optometry Biomedical technology focused on stimulating tissue healing and regeneration through the application of growth factors and other proteins that are present in plasma <<<<<<<<<<<<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) GENYO-13002 Lentiviral Systems Others Others Insulator for improve gene expression <<<<<<<<<<<<<<<<<<<<<<<<<IRYCIS App for Antibiotic prescription Others Infections / Others New App to support antibody prescription in ER <<<<<<<<<<<<<<<<<<<<<<<<< SpainIRYCIS Medical Device for alopecia monitoring Medical devices Dermatology Medical device for a standarized monitoring of alopecia <<<<<<<<<<<<<<<<<<<<<<<<< SpainIRYCIS/UC3M Biopsypunch Medical devices Dermatology New device for dermatological biopsies <<<<<<<<<<<<<<<<<<<<<<<<< SpainREIG JOFRE/LABORATORIOS MEDEA Gynec Medical devices Cancer Endometrial cancer <<<<<<<<<<<<<<<<<<<<<<<<< SpainStem Center S.L.U. GID System Medical devices Others Plastic and reconstructive surgery <<<<<<<<<<<<<<<<<<<<<<<<< SpainZeClinics ZeCardio Others Cardiovascular and circulatory systems In vivo imaging software for cardiovascular analysis. ZeCardio: HD video microscope software for the in vivo quantification of heart and vascular parameters in zebrafish larvae <<<<<<<<<<<<<<<<<<<<<<<<< SpainHistocell HR007 Medical devices Dermatology Tissular Regeneration <<<<<<<<<<<<<<<<<<<< EuropeHistocell Reoxcare Gel® Medical devices Dermatology Wound healing <<<<<<<<<<<<<<<<<<<< EuropeIRYCIS Telereha: platform for monitoring cardiac rehabilitation Others Cardiovascular and circulatory systems eHealth platform based on mhealth tecnologies for the development of custom cardiac rehabilitaion programs <<<<<<<<<<<<<<< SpainIRYCIS Smartphone-based platform for teledermatology Others Dermatology Communication channel between primary care physicians and dermatologists <<<<<<<<<<<<<<< SpainIRYCIS Virtual reality and cognitive rehabitlitation Others Central Nervous System Virtual reality for rehabilitation of patitients with heminegligencies <<<<<<<<<<<<<<< SpainPRAXIS POLYHEAL Medical devices Dermatology Bioactive wound dressings (Diabetic / vascular) <<<<<<<<<<<<<<< EuropePRAXIS Kit-Chagas Medical devices Others Chagas <<<<<<<<<<<<<<< EU /USA /LAFUND. PROGRESO Y SALUD / OTT (SAS) GENYO-13007 MSCs Biomarker Others Others Surface marker for MSCs <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) GENYO-13006 Others Others Multipotent Mesenchimal Stroma Cells Subpopulation <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-140 Biomaterials & Tissue Therapy Dental Resorbable membrane for guided bone regeneration <<<<<<<<<<FUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) Osteoblast-enriched bone allograft Biomaterials & Tissue Therapy Analgesia & Pain Spinal fusion <<<<<<<<<< SpainFUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) Titanium materials anodised with fluorine Biomaterials & Tissue Therapy Analgesia & Pain New material with antibacterial properties <<<<<<<<<< SpainHistocell HR018 Medical devices Dental Soft tissues regeneration. Oral mucose <<<<<<<<<< EuropeIRYCIS Telemedicine platfroms Others Cancer / Others Comprehensive management of upper lymphedema after breast cancer, including its early detection, a practical-theoretical training and the possibility of contact with the specialist <<<<<<<<<< SpainALGENEX (Alternative Gene Expression S.L.) CrisBio Others Autoimmune & Inflammation / Others Technology platform to produce recombinant proteins for use in diagnostics or vaccine development using insect pupae as a host with BEVS <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO 14014 Biomaterials & Tissue Therapy Ophthalmology and optometry Blepharitis, dry eye syndrom, various opthtalmologic diseases <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO 13003 Biomaterials & Tissue Therapy Cardiovascular and circulatory systems Angiogenesis <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13024 Medical devices Infections Sterility three-way stopcoks and tube connectors. <<<<< SpainFUND. PROGRESO Y SALUD / OTT (SAS) GENYO-13008 Others Blood and Lymphatic systems Method for obtaining megakaryocytes and platelets <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) LARCEL-14001 Others Others Method for generating Induced Pluripotent Stem Cells (iPSC) <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) CABIMER-13005 Culture Medium and Biomaterial Biomaterials & Tissue Therapy Others Mesothelial cells in Tissue Bioengineering <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) CABIMER-13004 Culture Medium Others Central Nervous System Xeno-free culture and differentiation medium to convert hPSC to neural progenitors <<<<<FUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) Osteostatin-based biomaterial Biomaterials & Tissue Therapy Autoimmune & Inflammation / Others Bone regeneration and Tissue engineering <<<<< SpainFUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) Materials with controlled-release of bioactive agents Biomaterials & Tissue Therapy Autoimmune & Inflammation/ Musculoeskeletal disorders Osteomyelitis (Bone implants) <<<<< SpainIRYCIS New software for interpretation of renal ultrasound images Others Kidney and Genitourinary system Software for interpretate ultrasound renal images by a non specialist in ultrasound <<<<< Spain

OTHER TECHNOLOGIES

COMPANY PRODUCT TYPE THERAPEUTIC AREA INDICATION R +D Preliminary Validation

Clinical Validation Register Ready to

marketStudies location

AB-Biotics Neuropharmagen Biomarkers Central Nervous System Pharmacogenetic test to identify the most suitable medication for each neuropsychiatric patient <<<<<<<<<<<<<<<<<<<<<<<<<AC-Gen Reading Life OvaSeq Biomarkers / Diagnostic Cancer Ovarian and Breast Cancer NGS genetic test <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life ColonSeq Biomarkers / Diagnostic Cancer Colon Cancer NGS genetic test <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life BreastSeq Biomarkers / Diagnostic Cancer Breast Cancer NGS genetic test <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life HC-Gen Test Biomarkers / Diagnostic Cancer Hereditary Cancer NGS genetic test <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life HD-Gen test Biomarkers / Diagnostic Cancer NGS targeted panel for Hereditary Diseases Test <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life MitoSeq Biomarkers / Diagnostic Genetic Diseases and Dysmorphic syndromes Whole Mitochondrial Sequencing <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life WMicroSeq Others Infections Whole Bacterial and Viral Genome Sequencing <<<<<<<<<<<<<<<<<<<<<<<<< SpainAC-Gen Reading Life PancSeq Biomarkers / Diagnostic Cancer Pancreatic cancer NGS genetic test <<<<<<<<<<<<<<<<<<<<<<<<< SpainAraclon Biotech Kit ABtest40 / 17 / 42 Biomarkers Central Nervous System Alzheimer´s disease diagnostic kit in the early stages <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideBTI Biotechnology Institute Ophthalmology kit - KMU11 Others Ophthalmology and optometry Indicated for the treatment of ocular surface pathologies <<<<<<<<<<<<<<<<<<<<<<<<< ESPAÑABTI Biotechnology Institute BTI APNiA Diagnostic Respiratory and Pulmonary system Respiratory polygraphy of 5 channels for the diagnosis of obstructive sleep apnea <<<<<<<<<<<<<<<<<<<<<<<<< EspañaBTI Biotechnology Institute Surgery kit - KMU18 Others Ophthalmology and optometry Indicated for surgeries of the ocular surface <<<<<<<<<<<<<<<<<<<<<<<<< SPAINCYTOGNOS Act-t4 Cell Kit Biomarkers Autoimmune & Inflammation / Infections / Others Antibody kit for the identification and quantification by flow cytometry of activated CD4 T-cells <<<<<<<<<<<<<<<<<<<<<<<<< SpainFERRER EPICUP (FAB-115) Diagnostic Cancer Cancer of Unkown Primary <<<<<<<<<<<<<<<<<<<<<<<<< EuropeFundacion MEDINA In vitro tests for toxicity, safety, ADME and plasma efficacy Diagnostic/ Imaging Others Cytotoxicity, Neurotoxicity, Mitochondrial Toxicity, Cardiotoxicity, ADME tox <<<<<<<<<<<<<<<<<<<<<<<<< Spain

Health in Code Genetic diagnosis of inherited cardiovascular diseases Diagnostic Cardiovascular and circulatory systems / Genetic Diseases and Dysmorphic syndromes Cardiovascular Diseases <<<<<<<<<<<<<<<<<<<<<<<<<

Europe, Middle East, North America

and LatinamericaIMEGEN Clinical exome Diagnostic Genetic Diseases and Dysmorphic syndromes Exome sequencing clinically customized <<<<<<<<<<<<<<<<<<<<<<<<<IRYCIS Biomarkers toidentify IFN-BETA drug response in multiple sclerosis Biomarkers / Diagnostic Autoimmune & Inflammation / Central Nervous System New patented method to identify good responders to Interferon beta (INF-beta) therapy in multiple sclerosis before treatment initiation <<<<<<<<<<<<<<<<<<<<<<<<< SpainLeitat Ready-to-use transport kits for xenobiotic interaction studies Others Others To identify xenobiotic interactions for regulatory purposes <<<<<<<<<<<<<<<<<<<<<<<<< EuropeLife Length Telomere Analysis Technology (TAT Test) Biomarkers / Diagnostic Cancer / Cardiovascular and circulatory systems Age related diseases, Cancer, Cardiovascular, Degenerative diseases <<<<<<<<<<<<<<<<<<<<<<<<< EuropeMyriad Genetics Vectra® DA Biomarkers Autoimmune & Inflammation / Musculoskeletal Disorders Multi-biomarker blood test validated to measure Rheumatoid Arthritis <<<<<<<<<<<<<<<<<<<<<<<<<Neuron Bio Alz Test Biomarkers / Diagnostic Central Nervous System Discriminatory diagnostic tool between Alzheimer´s disease and Mild cognitive impairment <<<<<<<<<<<<<<<<<<<<<<<<< SpainOPERON Simple GDH Biomarkers / Diagnostic Digestive System / Infections One-step immunochromatographic test for the qualitative detection of GDH from C. difficile in human faeces <<<<<<<<<<<<<<<<<<<<<<<<<OWL Metabolomics Owl Liver ® Care Biomarkers / Diagnostic Digestive System Non-alcoholic fatty liver disease (NAFLD) <<<<<<<<<<<<<<<<<<<<<<<<< Europe and AmericaOWL Metabolomics OWLSkin Biomarkers Dermatology Dermatitis and other skin diseases <<<<<<<<<<<<<<<<<<<<<<<<< EuropeOWL Metabolomics OWLiver Biomarkers / Diagnostic Digestive System Non-alcoholic steatohepatitis (NASH) <<<<<<<<<<<<<<<<<<<<<<<<< Europe and AmericaSECUGEN GENOTYPING Diagnostic/ Imaging Ophthalmology and optometry Genetic risk for Age related Macular Degeneration <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSECUGEN DNA SEQUENCING Diagnostic/ Imaging Genetic Diseases and Dysmorphic syndromes Genetic Diagnosis <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSECUGEN Service for the detection and quantification of autoantibodies against CFH and CFI Biomarkers Autoimmune & Inflammation / Genetic Diseases and Dysmorphic syndromes Complement system related disorders <<<<<<<<<<<<<<<<<<<<<<<<< SpainSISTEMAS GENÓMICOS OTOGeneProfile® Biomarkers Ophthalmology and optometry Hearing Impairment <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS ONCOGeneProfile® Biomarkers Cancer Oncology <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS Inmutest® Biomarkers Autoimmune & Inflammation Food intolerance <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS Nuevo CardioGeneProfile® Biomarkers Cardiovascular and circulatory systems Cardiovascular Risk <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS MamaGeneProfile® Biomarkers Cancer Breast Ovarian cancer <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS Oncopharma GeneProfile Biomarkers / Diagnostic Cancer 136 genes established as biomarkers for the toxicity and response to the most common drugs in Oncology <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS GeneSGKits Diagnostic Kit for capture and sequencing of genes from DNA with CE <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS BabyTest Plus Diagnostic Genetic Diseases and Dysmorphic syndromes For pregnants <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS DI GeneProfile Biomarkers / Diagnostic Central Nervous System Paediatrics <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS Onco-GeneSGKits Biomarkers / Diagnostic Cancer Hereditary cancer <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS OSTEOGeneProfile® Biomarkers Musculoskeletal Disorders Osteodisplasias and collagenopathies <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS MRisk® Biomarkers Cancer Melanoma <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideSISTEMAS GENÓMICOS NeuroGeneProfile® Biomarkers Central Nervous System Neurological diseases <<<<<<<<<<<<<<<<<<<<<<<<< WorldwideVENTER PHARMA LacTEST 2,7 powder for oral solution Diagnostic Autoimmune & Inflammation / Digestive System Subject with lactose intolerance <<<<<<<<<<<<<<<<<<<<<<<<<Vivia Biotech Personalized Medicine Test in Haematological Malignancies Diagnostic Blood and Lymphatic systems / Cancer Acute Myeloid Leukaemia <<<<<<<<<<<<<<<<<<<<<<<<< EuropeBiomedal iVYLISA GIP Others Autoimmune & Inflammation / Digestive System Monitoring of the gluten free diet in celiac patients <<<<<<<<<<<<<<<<<<<< SpainIMMUNOSTEP Infiltration in CNS Diagnostic Cancer Detection of Leptomeningeal disease <<<<<<<<<<<<<<<<<<<< WorldwidePANGAEA ONCOLOGY EGFR serum mutation test Biomarkers Cancer Lung cancer, EGFR mutated <<<<<<<<<<<<<<<<<<<< WorldwideProgenika Biopharma ID XT Diagnostic Blood and Lymphatic systems Blood group genotyping <<<<<<<<<<<<<<<<<<<<AMADIX (Advanced marker discovery) Personalized Medicine Biomarkers Cancer Lung Cancer prognostic and predictive test <<<<<<<<<<<<<<< SpainAMADIX (Advanced marker discovery) Colofast Biomarkers / Diagnostic Cancer Colon Cancer: diagnostic test <<<<<<<<<<<<<<< Spain and EuropeATRYS HEALTH Personalized Medicine Patient monitoring equipment Cancer Expert system for breast and colon cancer patient management <<<<<<<<<<<<<<< SpainATRYS HEALTH Personalized Medicine Biomarkers Cancer Patient stratification in glioma <<<<<<<<<<<<<<< SpainATRYS HEALTH Personalized Medicine Biomarkers / Diagnostic Cancer Patient stratification for difuse large b-cell lymphoma therapy <<<<<<<<<<<<<<< SpainBiocross Multiparametric test Biomarkers Central Nervous System Alzheimer's disease <<<<<<<<<<<<<<< EuropeBiokit S.A BIO-FLASH® HBe Ag Diagnostic Infections Hepatitis B <<<<<<<<<<<<<<<Biokit S.A BIO-FLASH® VZV IgG and IgM Diagnostic Infections Varicella <<<<<<<<<<<<<<<Biokit S.A BIO-FLASH® Mumps IgG Diagnostic Infections Mumps <<<<<<<<<<<<<<<Biokit S.A BIO-FLASH® Measles IgG Diagnostic Infections Measles <<<<<<<<<<<<<<<Biokit S.A BIO-FLASH® HSV 1+2 IgM Diagnostic Infections Herpes 1 and Herpes 2 <<<<<<<<<<<<<<<Biokit S.A BIO-FLASH® HIV-1+2 Ag/Ab Diagnostic Infections HIV <<<<<<<<<<<<<<<Biokit S.A BIO-FLASH® anti-HBe Diagnostic Infections Hepatitis B <<<<<<<<<<<<<<<CYTOGNOS Diagnosis and MRD Euroflow tubes Biomarkers / Diagnostic Blood and Lymphatic systems / Cancer Multiple Myeloma patients by flow cytometry <<<<<<<<<<<<<<< SpainFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13039 Biomarkers Infections Hepatitis C <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-120 Diagnostic/ Imaging Genetic Diseases and Dysmorphic syndromes / Musculoskeletal Disorders Duchenne muscular dystrophy (DMD) and others <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-13004/13005 Biomarkers Infections Hepatitis C <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-62 Diagnotic Image Analisis tool Diagnostic/ Imaging Digestive System Fibrosis / NASH (non-alcoholic steatohepatitis) <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) GENYO-1 Circultaing Biomarkers Biomarkers Cancer Metastasis <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-80 Multiple Sclerosis Diagnostic Kit Biomarkers Autoimmune & Inflammation / Central Nervous System Multiple sclerosis <<<<<<<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-14017 Diagnostic/ Imaging Central Nervous System Parkinson's disease and other parkinsonims <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-14001 Biomarkers Cancer Endometrial carcinoma <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-13008 Biomarkers Cancer Colorectal cancer <<<<<<<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-133 Biomarkers Cancer Chronis obstructive respiratory disease / Lung cancer (adenocarcinoma) <<<<<<<<<<<<<<< EuropeFundacion MEDINA Biomarkers Platform Biomarkers / Diagnostic Cancer Lung Colon Breast Pancreas <<<<<<<<<<<<<<< SpainFundacion MEDINA Metabolomics Biomarkers Identification Platform Biomarkers / Diagnostic Cancer / Infections / Metabolic / Endocrinology Cancer Infectious Metabolism and Infectious Biomarkers <<<<<<<<<<<<<<< SpainGendiag Cardio inCode in Cardiovascular Kidney Disease Biomarkers / Diagnostic Cardiovascular and circulatory systems Clinical-genetic approach to assessing cardiovascular risk in patients with chronic kidney disease <<<<<<<<<<<<<<< SpainGendiag Cardio inCode in Cardiovascular Kidney Disease Biomarkers / Diagnostic Cardiovascular and circulatory systems Evaluate the association between genetic risk and coronary calcification in coronary arteries in patients with renal failure <<<<<<<<<<<<<<< SpainGendiag Thrombosis in cancer Biomarkers / Diagnostic Cardiovascular and circulatory systems Evaluate the capability of new clinical-genetic algorithms (Thrombo inCode) for the identification of cancer patients at risk of developing VTE in comparison to the standard risk assessment method, <<<<<<<<<<<<<<< Spain and AustriaGendiag Thrombosis in recurrent pregnancy loss Biomarkers / Diagnostic Women´s health Evaluate the capability of new clinical-genetic algorithms (Thrombo inCode) for the identification recurrent pregnancy loss patients related with thrombophilia in comparison to the standard risk assessment method <<<<<<<<<<<<<<< SpainIMMUNOSTEP Hemodilución (Bmplex) Diagnostic Blood and Lymphatic systems Detection of hemodilution in bone marrow samples <<<<<<<<<<<<<<< WorldwideIRYCIS miRNA 127 agents for use in the treatment of renal fibrosis Biomarkers / Diagnostic Kidney and Genitourinary system a method of prophylactically or therapeutically treating Chronic kidney disease (CKD) or of reducing the risk of CKD disease progression in a patient comprising expressing miR-127 in the renal cells <<<<<<<<<<<<<<< SpainIRYCIS Noverl biomarkers of acute kidney injury based on miRNAs Biomarkers / Diagnostic Kidney and Genitourinary system The identified panel of miRNAs can detect acute kidney injury (AKI) development before serum creatinine increases <<<<<<<<<<<<<<< SpainIRYCIS Biomarkers immunotherapy treatment Biomarkers / Diagnostic Autoimmune & Inflammation / Others Biomarkers based on IgE profile for determining oral immunotherapy treatment response in children with cow’s milk protein allergy <<<<<<<<<<<<<<< SpainMyriad Genetics myPath™ Melanoma Biomarkers / Diagnostic Cancer Genetic profile to test pathogenic status of Melanoma biopsy <<<<<<<<<<<<<<< WorldwideMyriad Genetics myPlan™ Lung Cancer Diagnostic Cancer Lung Cancer prognostic test based on Cell Cycle Progression Genes <<<<<<<<<<<<<<< WorldwideMyriad Genetics myPlan™ Renal Cancer Biomarkers / Diagnostic Cancer Test Prognostics for renal cancer <<<<<<<<<<<<<<<Myriad Genetics myChoice™ HRD Biomarkers / Diagnostic Cancer Companion diagnostic test to identify metastatic breast cancer, ovarian and other tumor types that may be sensitive to iPAPR and/or platinum <<<<<<<<<<<<<<< WorldwideOWL Metabolomics OWLfat Biomarkers / Diagnostic Digestive System Non-alcoholic fatty liver disease <<<<<<<<<<<<<<< EuropeOWL Metabolomics OWLfiber Biomarkers / Diagnostic Digestive System Liver Fibrosis <<<<<<<<<<<<<<< Europe and AmericaOWL Metabolomics OWLiver ® ASH Biomarkers / Diagnostic Digestive System Alcoholic esteatohepatitis <<<<<<<<<<<<<<< EuropePANGAEA ONCOLOGY BRCA1 RNA test Biomarkers Cancer Solid tumours <<<<<<<<<<<<<<< WorldwidePANGAEA ONCOLOGY EGFR enrichment test Biomarkers Cancer Lung cancer, EGFR mutated <<<<<<<<<<<<<<< WorldwideProgenika Biopharma Promonitor Patient monitoring equipment Autoimmune & Inflammation Monitoring of biologics <<<<<<<<<<<<<<<SISTEMAS GENÓMICOS EPILEPSY-GeneProfile Biomarkers / Diagnostic Central Nervous System Next-Generation Sequencing panel of 352 genes associated with epilepsy of family origin <<<<<<<<<<<<<<< WorldwideVivia Biotech Personalized Medicine Test in Haematological Malignancies Biomarkers / Diagnostic Blood and Lymphatic systems / Cancer Acute Lymphocytic Leukaemia <<<<<<<<<<<<<<< EuropeVivia Biotech Personalized Medicine Test in Haematological Malignancies Biomarkers / Diagnostic Blood and Lymphatic systems / Cancer Chronic Lymphocytic Leukaemia <<<<<<<<<<<<<<< EuropeVivia Biotech Personalized Medicine Test in Haematological Malignancies Biomarkers / Diagnostic Cancer Multiple Myeloma <<<<<<<<<<<<<<< EuropeAMADIX (Advanced marker discovery) PancreaDix Biomarkers / Diagnostic Cancer Early diagnosis of pancreatic cancer and precursor lesions <<<<<<<<<< SpainAMADIX (Advanced marker discovery) DiagnoLung Biomarkers / Diagnostic Cancer Early diagnosis of lung cancer <<<<<<<<<< SpainAPTUS Biotech AptaDetect-HCV Diagnostic Infections Hepatitis C Virus (HCV) <<<<<<<<<< SpainAPTUS Biotech Apta-Leish Diagnostic Infections Leishmaniasis <<<<<<<<<< SpainAPTUS Biotech ChikTest Biomarkers / Diagnostic Infections Chikungunya <<<<<<<<<< SpainATRYS HEALTH ProstatePredict Biomarkers / Diagnostic Cancer Diagnostic and Prognostic biomarkers for prostate cancer <<<<<<<<<< SpainBIOEF - H. Univ. Donostia/BIODONOSTIA Predictor of PML Biomarkers Autoimmune & Inflammation / Central Nervous System Predictor of the risk of developing progressive multifocal leucoencephalopathy in natalizumab-treated multiple sclerosis patients <<<<<<<<<<BIOEF - H. Univ. Cruces/BIOCRUCESUPV/EHU Diagnosis and prognosis of melanoma Biomarkers Cancer Diagnosis and Prognosis of melanoma <<<<<<<<<<BIOEF - Hospital Universitario Araba/BIOARABA Predictor of good response in FEP Biomarkers Central Nervous System Future good response to antipsychotic drugs in first-episode psychosis (FEP) disorders <<<<<<<<<<Biokit S.A BIO-FLASH ® EBV Diagnostic Infections Epstein-Barr Virus Infection <<<<<<<<<<Biokit S.A HTLV Ab Diagnostic Infections Human T-lymphotropic virus infection <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FISEVI-121 Others Autoimmune & Inflammation Transplant <<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) GENYO-13001 / FIMABIS-13009 Biomarkers Autoimmune & Inflammation Lupus erythematosus / Allergy <<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-45 Biomarkers Cardiovascular and circulatory systems Vascular Calcification <<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-85 Acute Kidney Injury Diagnostic Kit Biomarkers Kidney and Genitourinary system Acute Renal Failure <<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-92-93-122-130-141/FISEVI-124-125-133 Biomarkers / Diagnostic Cancer Adenocarcinome, Breast, Lung, Colorectal, Cervix tumours and Pancreas cancer / 5-FU treatment Prognosis <<<<<<<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-14007 Diagnostic/ Imaging Autoimmune & Inflammation Allergic rhinitis <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-14005 Biomarkers Cancer Breast cancer <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-94 Biomarkers Blood and Lymphatic systems / Cancer Acute Lymphoblastic Laeukemia (ALL) <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-14008 Biomarkers Cancer Lung cancer screening <<<<<<<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-14007 Biomarkers Cancer Circulating stem cells <<<<<<<<<< EuropeFUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) New kit for detection and quantification of Sin a1 (Yellow mustard) Diagnostic Metabolic / Endocrinology Food Mustard Allergy <<<<<<<<<< SpainGENOMICA NEDXA Diagnostic/ Imaging Others Point of Care instrument/ Lab on a Chip <<<<<<<<<< Spain,IMMUNOSTEP Disposable device for leukocyte separation Diagnostic Autoimmune & Inflammation / Blood and Lymphatic systems Hematological malignancies <<<<<<<<<< SpainLeitat ELISA kit to detect biomarker levels (S100A7) Biomarkers / Diagnostic Autoimmune & Inflammation / Cancer Diagnosis and prognosis of several cancers <<<<<<<<<< SpainLeitat ELISA kit to detect biomarker levels (S100P) Biomarkers / Diagnostic Autoimmune & Inflammation / Cancer Diagnosis and prognosis of Pancreatic cancer, colon cancer, others <<<<<<<<<< SpainLeitat ELISA kit to detect biomarker levels (S100A4) Biomarkers / Diagnostic Autoimmune & Inflammation / Cancer Diagnosis and prognosis of Pancreatic cancer, colon cancer, others <<<<<<<<<< SpainLife Length qPCR Biomarkers / Diagnostic Cancer / Cardiovascular and circulatory systems Age related diseases, Cancer, Cardiovascular, Degenerative diseases <<<<<<<<<<PRAXIS THERAGLIO Diagnostic Cancer Glioma <<<<<<<<<< EUROPEThrombotargets Diagnosis sensor Diagnostic Central Nervous System Alzheimer Disease <<<<<<<<<< EuropeATRYS HEALTH Personalized Medicine Biomarkers Cancer / Digestive System Biomarker for Gastric cancer <<<<< SpainATRYS HEALTH mAb for diagnosis and prognosis of brain tumors and lesions Biomarkers / Diagnostic Cancer / Central Nervous System Glioblastoma, neurodegenerative disease <<<<< SpainBIOEF - Hospital Universitario Donostia/BIODONOSTIA Genetic diagnostic based on pooled DNA Diagnostic Genetic Diseases and Dysmorphic syndromes Genetic diagnostic based on pooled DNA <<<<<BIOHOPE Immunosuppresors/ Immunomodulators in vitro bioassay Biomarkers / Diagnostic Autoimmune & Inflammation Renal Transplant: immunomodulation, immunosuppresion, tolerance induction. This bioassay helps define the best treatment combination possible for a certain patient to control rejection and

avoid over immunosuppresion <<<<< SpainBIOHOPE Diagnostic software rejection/tolerance Biomarkers / Diagnostic Autoimmune & Inflammation / Kidney and Genitourinary system Renal Transplant. Stratification of transplanted patients according to their immunological response <<<<< SpainBiokit S.A BIO-FLASH ® HAV Diagnostic Infections Hepatitis A <<<<<Biokit S.A BIO-FLASH ® Parvovirus Diagnostic Infections Parvovirus infection <<<<<CYTOGNOS Euroflow PID tubes Biomarkers / Diagnostic Autoimmune & Inflammation Antibody kit for the diagnosis of immunodeficiencies by flow cytometry <<<<< SpainCYTOGNOS Diagnosis flow cytometry kit Diagnostic Cancer Multiple Myeloma, Non-Hodgkin Lymphoma and Glioma <<<<< EuropeCYTOGNOS Diagnosis flow cytometry kit Diagnostic/ Imaging Infections Diagnosis and follow-up of influenza, tuberculosis, hepatitis C and HIV <<<<< Australia and EuropeCYTOGNOS Diagnosis flow cytometry kit Diagnostic Autoimmune & Inflammation Diagnosis and follow-up of allergies (Type I Hypersensitivity) <<<<< EuropeFECYT Diagnosis Diagnostic/ Imaging Infections Malaria <<<<<FERRER EPIBREAST (FAB-118) Diagnostic Cancer Breast Cancer <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13005 Biomarkers Cancer Colon Cancer <<<<< SpainFUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-14001 Diagnostic Cancer Hepatocarcinoma diagnosis <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIMABIS-15003 Biomarkers Metabolic / Endocrinology Diabetes / metabolic diseases <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) CABIMER-15004 Biomarkers Central Nervous System Amyotrophic Lateral Sclerosis <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-14010 Biomarkers Central Nervous System Meniere Disease <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13004 Biomarkers Cancer Colon Cancer <<<<< EuropeFUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-14025 Diagnostic Infections Hepatitis C <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-144/ 13019 Biomarkers Central Nervous System Meniere Disease <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO 14008 Diagnostic Cancer Lung cancer <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13004 Biomarkers Cancer Colon Cancer <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-15015 Biomarkers Cancer lung cancer <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13038 / FIBICO-13007 Biomarkers Cancer Cancer / Treatment of angiogenesis <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-15013 Diagnostic Infections Systemic infection <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) CABIMER-13001 Trombosis risk biomarker Biomarkers Cardiovascular and circulatory systems Mesenchymal Stem Cells (MSCs) <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-15012 Biomarkers Cancer Prostate <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-15004/ FIBAO14021 Diagnostic Infections Diagnostic Kit Hepatitis C <<<<< SpainFUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-13040 Others Digestive System Anastomosis <<<<< SpainFUND. PROGRESO Y SALUD / OTT (SAS) CABIMER-13002 Kit for hepatic fibrosis and cirrhosis diagnosis Biomarkers Digestive System Hepatic Fibrosis and Cirrhosis <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-14020 Diagnostic Infections Hepatitis C <<<<< SpainFUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-14009 Biomarkers Autoimmune & Inflammation  Rheumatoid arthritis <<<<<FUND. PROGRESO Y SALUD / OTT (SAS) FIBAO-15012 Biomarkers Central Nervous System Meniere Disease <<<<< europeFUND. PROGRESO Y SALUD / OTT (SAS) FIBICO-14025 Diagnostic Infections Hepatitis C <<<<<FUNDACIÓN JIMÉNEZ DÍAZ (Instituto de Investigación Sanitaria) Kit for Diagnosis and Prognosis Biomarkers / Diagnostic Kidney and Genitourinary system Chronic Kidney Disease (CKD) <<<<< SpainIMEGEN NGS diagnostic Kits Diagnostic Genetic Diseases and Dysmorphic syndromes Ready to use customized kits for using in NGS platforms <<<<<INBIOMOTION OSTEOMET Biomarkers Cancer Breast and Prostate cancer <<<<<Leitat Tailored-made formulations with nanoencapsulated active compounds Others Autoimmune & Inflammation  Atopic dermatitis, psoriasis <<<<< SpainLeitat Metabolic profile Biomarkers Infections Helicobacter pylori infection, oxidative stress <<<<< SpainLeitat In vitro cellular model for diagnosis Biomarkers Infections Helicobacter pylori virulence <<<<< SpainMerck / Sysmex Inostics Liquid Biopsy RAS Biomarker Testing Biomarkers / Diagnostic Cancer Metastatic colorectal cancer <<<<< SpainOPERON Simple Calprotectin Diagnostic Digestive System One-step immunochromatographic test for the qualitative detection of Calprotectin in human faeces <<<<<OPERON CT Oligogen Biomarkers / Diagnostic Infections Genetic test designed for the detection of Chlamydia trachomatis <<<<<OPERON MG Oligogen Biomarkers / Diagnostic Infections Test designed for the detection of Mycoplasma genitalium <<<<<OPERON NG Oligogen Biomarkers / Diagnostic Infections Test designed for the detection of Neisseria goorrhoeae <<<<<PANGAEA ONCOLOGY DX multiplex Non invasive Diagnostic/ Imaging Cancer Various tumours <<<<< EuropeStemTek Therapeutics Treatment prediction system for advanced tumors Diagnostic Cancer Multiple cancers <<<<< SpainStemTek Therapeutics POC system based on detection of circulating biomarkers Biomarkers / Diagnostic Cancer Colon cancer <<<<< Spain and GermanyZeClinics ZeOncoTest Diagnostic/ Imaging Cancer ZeOncoTest: a cheap, fast and reliable personalized oncological test to determine cancer treatments using zebrafish embryos as xeno-hosts for human cancer cells <<<<< Spain