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Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab M I I P Center for Informatics Science Nile University, Egypt Abdallah G. Motaal Research Assistant, MSc. Candidate Nile University, Egypt

Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

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Page 1: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Special Topic In Cardiac MR Imaging

Medical Imaging & Image Processing Lab

M I I P

Center for Informatics ScienceNile University, Egypt

Abdallah G. MotaalResearch Assistant,

MSc. Candidate

Nile University, Egypt

Page 2: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

LayoutLayout

• Background

• Cardiac Magnetic Resonance Imaging

• Strain Encoded Imaging

Theory

Anatomy Image Enhancement

Strain values correction

Page 3: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Background• Magnetic resonance imaging (MRI) is a safe,

noninvasive imaging technique that creates detailed images of organs and tissues.

• MRI uses radio waves and magnets to create images of organs and tissues, unlike computed tomography or conventional x rays,

MRI imaging does not use ionizing radiations.

Page 4: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

MR Cardiac Imaging• Cardiac MR is used to image the heart while it is

beating, producing both still and moving pictures of the heart and major blood vessels.

• Cardiologists use cardiac MR to get images and to look at the structure and function of the different region of the heart. These images can help them decide how best to treat patients with heart problems.

Page 5: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal
Page 6: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Cardiac Imaging (2)• Cardiac MRI is a common test for diagnosing

and evaluating a number of diseases and conditions, including:

Coronary artery disease Heart valve problems Congenital heart defectsCardiomyopathiesCardiac Tumors

Image with a cardiac infarction

Page 7: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

What is SENCWhat is SENC• SENC is a technique that is used to quantify regional

function of heart by direct encoding of regional strain of the heart into the acquired image.

• The technique measure the strain in the direction orthogonal to the image plane.

• Therefore, in case of short-axis images, only the longitudinal compression of the myocardium from base to apex is measured. On the other hand, circumferential shortening of the myocardium can be measured in the long-axis views of the heart (such as the four-chamber view).

Page 8: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Short Axis

Page 9: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Theory• Tagging– Tags are temporary non-invasive markers

whose deformations follow the motion of underlying tissue.

Diastole Systole Diastole Systole

Cardiac image before and after applying SPAMM tagging

Page 10: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Theory (2)• Tagging is done in the direction parallel to the image plane.• During cardiac cycle, these tag lines follow the motion of the

heart.

• So by knowing the change in the tagging frequency we can get the change in length, so we can calculate the strain.

Before Contraction After Contraction

Page 11: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Theory (3) Because of stretching and contraction of the heart, the tagging

frequency ranges from wl and wh.

Page 12: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Because of the contraction of the heart, the tagging frequency will change.

-wl wl 0 wh -wh

S(w)

M(z)

MyocardiumStatic Tissue

Page 13: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Color Mapping

• The normal longitudinal strain ranges from 5 to -25.• For qualitative assessment, strain values are represented by

colors.

5

-25

Page 14: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Time

Page 15: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Simulator

Page 16: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Time

% Strain

Page 17: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

• By adding both the L.T and H.T we will get an informative anatomical Image. But the elevated noise leads to poor contrast to noise ratio(CNR).

Anatomy Image Enhancement

Page 18: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

• Bayes classifier was used to increase the CNR.Based on statistical model of both background and

tissue signal

A. Motaal, M. Al-Attar, N. Osman ,A. Fahmy

CIBEC ’ 08IEEE Proceedings

Page 19: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Interleaving Strain Error Correction

Page 20: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

T SecondsT Seconds

The Total Time Taken is 2*T Seconds

T Seconds

The Total Time Taken is only T Seconds

Non - InterleavedNon - Interleaved

InterleavedInterleaved

Page 21: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

One-heartbeat Interleaved SENC Sequence

trigger

Problem: interframes motion of the heart

Page 22: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

. . . . . . . . . . . . . . .

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Correction AlgorithmCorrection Algorithm

w1 w2 w3 W nWn-1

Estimate w

DerivativeDerivative

Diff < β

Compare Wn-1

Compare Wn-1

NO

Yes

STOP

Proposed Correction Algorithm

Page 23: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Phantom Experiment

• Numerical Computer Simulation was done to generate SENC images with different strain curves, and the proposed algorithms were tested on them

Page 24: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

After CorrectionBefore Correction`

Time FrameTime Frame

Stra

in

Stra

in

Results

Page 25: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Results (cont.)

Page 26: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

SummarySENC is a technique for measuring regional

function of the heart.We developed a Bayesian method to improve

the anatomical image reconstructed from SENC.

We propose an algorithm to correct strain measurements in interleaved acquisition.

The technique enables the reduction of the required timeframes; hence, faster and better quality imaging.

Page 27: Special Topic In Cardiac MR Imaging Medical Imaging & Image Processing Lab MIIP Center for Informatics Science Nile University, Egypt Abdallah G. Motaal

Thank You !

[email protected]