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Subcutaneous Mycoses Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Dr. Abd El Raouf Al Manaama Manaama

Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

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Page 1: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Subcutaneous MycosesSubcutaneous Mycoses

Prepared By:

khaled A Elmoghrabykhaled A Elmoghraby

Supervised By:

Dr. Abd El Raouf Al ManaamaDr. Abd El Raouf Al Manaama

Page 2: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Subcutaneous MycosesSubcutaneous Mycoses

These are caused by fungi that grow in soil and on vegetation and are introduced into subcutaneous tissue through trauma.

Page 3: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

sporotrichosis

Sporothrix schenckii is a dimorphic fungus that live on vegetation. When introduced into the skin, typically by a thorn, it cause a local pustule or ulcer with nodules along the draining lymphatics .

Page 4: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

sporotrichosis

There is little systemic illness. Lesion may be chronic . Sporotrichosis occure most often in gardeners, especially those who prune roses, because they may be stuck by a rose thorn.

Page 5: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

sporotrichosis

In the clinical laboratory, round or cigar-shaped budding yeasts are seen in tissue specimen. In culture, hyphae occure bearing oval conidia in clusters at the tip of slender conidiophores (resembling a daisy). The drug of choice for skin lesions is itraconazole. It can be prevented by protecting skin when touching plants, moss, and wood.

Page 6: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

sprotrichosis

Sporotrichosis, infection with the fungus Sporothrix schenckii.

Page 7: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

sprotrichosis

Sporotrichosis ulcer.

Page 8: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Chromoycosis

This is a slowly progressive granulomatous infection that is caused by several soil fungi (Fonsecaea, phialophora, cladosprium, etc) when introduced into the skin through the trauma. These fungi are collectively called dematiaceous fungi, so named because their conidia or hyphae are dark-colored, either gray or black.

Page 9: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Chromoycosis

Wartlike lesion with crusting abscesses extend along the lymphatics. The disease occure mainly in the tropics and is found on bare feet and legs. In the clinical laboratory, dark brown, round fungal cell are seen in leukocytes or giant cells. The disease is treated with oral flucytosine or thiabendazole, plus local surgery.

Page 10: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Chromoycosis

Chromoblastomycosis.

Page 11: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Chromoycosis

"Chromoblastomycosis, syn. chromomycosis; hyperkeratotic lesions foot; Fonsacaea (Phialophora) infection,

Page 12: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

mycetoma Soil organisms (petriellidium,

madurella) enter through wounds in the feet, hands, or back and cause abscesses, with pus discharge through sinuses. The pus contain compact colored granules.

Page 13: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

mycetoma Actinomycete such as nocardia can

cause similar lesions (Actinomycotic mycetoma). Sulfonamide may help the actinomycotic form. There is no effective drug againest the fungal form; surgical excision is recommended.

Page 14: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

mycetoma

Mycetoma of the arm.

Page 15: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

mycetoma

Mycetoma of the shoulder and back.

Page 16: Subcutaneous Mycoses Prepared By: khaled A Elmoghraby khaled A Elmoghraby Supervised By: Dr. Abd El Raouf Al Manaama

Khaled Moghraby